LOCUS       c00109_gnlPro..         9920 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|ADJPAMPF_109.
ACCESSION   c00109_gnlPro..
VERSION     c00109_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-07 19:21:26
            Original ID  :: gnl|Prokka|ADJPAMPF_109
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 9920
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..9920
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[248:4810]"
                     /cutoff="10000"
                     /detection_rule="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /neighbourhood="10000"
                     /product="succinate2propionate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      249..4810
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /neighbourhood="10000"
                     /product="succinate2propionate"
                     /protocluster_number="1"
     cand_cluster    1..9920
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /kind="single"
                     /product="succinate2propionate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..9920
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="succinate2propionate"
                     /region_number="1"
                     /rules="(minimum(4, [AcetylCoA_hyd_C, AcetylCoA_hydro,
                     B12-binding, Biotin_lipoyl, Glyoxalase_4, HMGL-like,
                     MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma, PYC_OADA]) and
                     minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /tool="gutsmash"
     CDS             complement(249..1409)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: OAD_beta"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg109_1"
                     /sec_met_domain="OAD_beta (E-value: 9.6e-154, bitscore:
                     500.7, seeds: 229, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGDFINFLGNNLADFWTYTGFANATGGHIAMIIIGLGFIYLAVAK
                     EFEPMLLIPIGFGILIGNIPFNMDAGLKVGIYEEGSVLNILYQGVTSGWYPPLIFLGIG
                     AMTDFSALISNPKLMLIGAAAQFGIFGAYMIALEMGFDPMQAGAIGIIGGADGPTAIFL
                     SSKLAPNLMGAIAVSAYSYMALVPVIQPPIMRLLTTKHERVIRMKPPRAVSHTEKVIFP
                     IIGLLLTCFLVPSGLPLLGMLFFGNLLKESGVTRRLANTASGPLIDVITILLGLTVGAS
                     TQASEFLTLDSIKIFALGALSFIIATASGVIFVKIFNLFLKKGNKINPLIGNAGVSAVP
                     DSARISQVVGLEYDPTNYLLMHAMGPNVAGVIGSAVAAGILLGFLM"
     CDS             complement(1411..1845)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: Biotin_lipoyl"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1024:Biotin-requiring enzyme (Score: 66.7; E-value:
                     4e-21)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg109_2"
                     /sec_met_domain="Biotin_lipoyl (E-value: 5.9e-22, bitscore:
                     66.7, seeds: 40, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKEYKYKINGNSYKVTIGDIEDNIAHVEVNGTHYKVEMEKQPKAT
                     PKPAVVRPMPNSPAAPTTPVVKPAAPSTGKSGVKSPLPGVILDIKVNVGDTVKRGQTII
                     ILEAMKMENNINADKDGKVTAINVNKGDSVLEGNDLVIIE"
     CDS             complement(1870..2790)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: OAD_gamma"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg109_3"
                     /sec_met_domain="OAD_gamma (E-value: 2.5e-15, bitscore:
                     46.2, seeds: 234, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNKTKIGIFLSLLLLIGLTSCGEQKSNNKLLLNEVLIDNQNNFQD
                     DYGLHSAWIEIFNKSYGSADLAACLLKVSSQPGDTVTYFIPKGDILTLVKPRQHALFWA
                     DGEPNRGTFHTSFKLNPETANWVGLFDSGRKLLDQVVIPAGTLGPNQSYARISDGAADW
                     EVKGGSKDKYVTPSTNNKTLDSNAKMEKFEEHDSVGIGMSISAMSVVFCGLILLFIAFK
                     VVGKVAVNLSKRNAMKAKGIDKVEAKELSQAPGEVYAAISMALHEMQDEVHDVEETVLT
                     ITRVKRSYSPWSSKIYTLRENPNRK"
     CDS             complement(2822..4375)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: CT_Btheta"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg109_4"
                     /sec_met_domain="CT_Btheta (E-value: 3e-291, bitscore:
                     955.2, seeds: 72, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSNQLEKIKELIERRAVARIGGGEKAIAKQHEKGKYTARERIAML
                     LDEGSFEEMDMFVEHRCTNFGMEKKHYPGDGVVTGCGTIEGRLVYLFAQDFTVTAGSLS
                     ETMSLKICKIMDQAMKMGAPCIGINDSGGARIQEGINALAGYAEIFQRNILASGVIPQI
                     SGIFGPCAGGAVYSPALTDFTLMMEGTSYMFLTGPKVVKTVTGEDVSQENLGGASVHST
                     KSGVTHFTAKTEEEGLALIRTLLSYIPQNNLEEAPYVDCTDPIDRLEDSLNDIIPDSPN
                     KPYDMYEVISAIVDNGEFLEIQKDYAKNIIIGFARFNGQSVGIVANQPKFLAGVLDSNA
                     SRKGARFVRFCDAFNIPIVSLVDVPGFLPGTGQEYNGVILHGAKLLYAYGEATVPKVTI
                     TLRKSYGGSHIVMSCKQLRGDMNYAWPTAEIAVMGGAGAVEVLYAREAKDQENPAQFLA
                     EKEAEYTKLFANPYNAAKYGYIDDVIEPRNTRFRVIRALQQLQTKKLSNPAKKHGNIPL
                     "
     CDS             complement(4406..4810)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: Glyoxalase_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg109_5"
                     /sec_met_domain="Glyoxalase_4 (E-value: 9.5e-25, bitscore:
                     76.4, seeds: 51, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKISHIEHLGIAVKSIEEALPYYENVLGLKCYNIETVEDQKVRTA
                     FLKVGETKIELLEPTCPESTIAKFIENKGAGVHHVAFAVEDGVANALAEAESKEIRLID
                     KAPRKGAEGLNIAFLHPKSTLGVLTELCEH"
     CDS             complement(4984..5982)
                     /locus_tag="ctg109_6"
                     /transl_table=11
                     /translation="MPLKLTTYYRGKDIPDLPGTNTFHSKELFQIYESTPGYTPLLIVA
                     TEEGRPVARLLAAIRKTKKWLPSSLVKQCVVYGAGEFLDTSLPASKEKEEEIFGEMLEH
                     LTQEASRTCILIEFRNLDNSMFGYRFFRKNDFFPVNWLRVRNSLHSTQKAEDRFSPSRI
                     RQIRKGLKNGAKVVEAHTVEEIKEFSRMLHKVYSSRIRRYFPANDFFRHMNSMLIRGKQ
                     AKIFIVKYKEKIIGGSVCIYSGENAFIWFSGGMRKTYALQSPGILAVWKALEDAHERGF
                     RHMEFMDVGLPFRKHGYRDFVLRFGGKQSSTRRWFRISWPWLNNLLVKFYV"
     CDS             6231..8354
                     /locus_tag="ctg109_7"
                     /transl_table=11
                     /translation="MRENAFVEAWKTQHRRVSMILGLTLLCAPSAISVYAENGVNDITV
                     QAVMQTKTVKGTVLDENGEPLIGVSIVVKGTSTGTITDFDGKFSINLPAGSKELVVSYI
                     GYKEQAIIVSGNAPLNIKMVPDTQALDEVVVIGYGTVKKRDLTGAVASVKSEDITMNPG
                     VNPMDALQGKIAGLDITNSSGQAGSSPTVQLRGTRSLQLDEDGNISSDAFKPTYIIDGM
                     PGDIATLNPNDIESIEVLKDASSTAIYGSSGANGVIIVTTKGSKSGKPVINFNAYAGTT
                     MGARVPKMRTGDSYINYIKDSYKPVGTTNEEEIFGERYDAIKNNQWVNWGDEVLHSGLK
                     QNYSISVAGGTEKTKAYFSLNYTDEKSMYENDDYKVYSTRVRIDQEINKWMNAGINVQA
                     SFSNKNSRNAVLERALFATPLGTPYNEDGSITEFPILGSSSDPNPLADEQDGVYKNNTK
                     AGRAYVDAYLEWKPVKGLSVKSQLGGSYSQSRAGKFMGEGSYNVLKGSTVAYGEATNKT
                     GYNYKWENIVTYHNTFNKDHDLTVTGVTSWNYNQSEEYYVYGENPATNDMLWYALQNAD
                     NKKLNSKYLMSKGMGFIGRVNYSYKGKYLFSASSRYEADSRLSKDNRWNLFPAVSVGWR
                     ISDEAFMAGTKSWLDNLKLRVGYGVAGTTAGIAEYSSMASLENVTTSLGGMTVPSAKFT
                     XXXXLRSISLTVI"
     CDS             8375..9442
                     /locus_tag="ctg109_8"
                     /transl_table=11
                     /translation="LNIGIDASFLNNRIDLTVDLYRTKTTDVILSQALPTSIMGNYTGS
                     TTYKMNKNAAETENRGIELALNTRNIVKKDFTWSSTVTFTANKEKIKSLIEGQDMMFNA
                     KKGDMVFKVGEGVGSFYRYKVLGIWQYSEKETAALFGCEPGDIKLDLPSVKKDGNGYYY
                     MNPEGERVDITAENPYGVRADYDRQVIGRNTPDWTLGFKNNFRYKDFDLSVFLYARWGQ
                     MMNYGSVIGKYSPNPDYNIPTYFTYYDKTIEADQDVLFYAIDKSKDRSAYEGYDSMYYV
                     DGSFFKLKNVTLGYTLPGKLTKRFGISNLRVYATMTNLFTYSPNKYVKNYDPEMNGSIN
                     FPLSRDCIFGLNLTF"
     CDS             9454..9918
                     /locus_tag="ctg109_9"
                     /transl_table=11
                     /translation="MKKIYSLVLLVAGVFSWGSCSLDEVNPNNSGQFSDGSYTLETYKA
                     FTNSCYTALINNIYQSSDYLVCTEAGTDIWEEPKSGSSYQRYHSYNGMKTDDSYYYKVW
                     QYSYLCINSCNIVIDGAENVTGDENEINECVAQARCLRAYYYMNLVEQFGN"
ORIGIN
        1 gtacaaagga aggcgaggag aataatccgt ttcataaata tttattttag tgtgtcgtaa
       61 caaagacgca agatgctaaa aaatatcgta tttacgaatt attcgtagcc tttttggaat
      121 agattaacgg aatgataaga gaagataaca taatgataag tgcggatatt gcatctaaaa
      181 cagcaatatc cgcacctaat attttgtccc ggcattccga atggaagcct gacaggggca
      241 ccttgtccct acattaagaa tcctaacagg ataccggcag caacagccga accgattaca
      301 cctgctacgt tcggacccat agcgtgcatc agcaagtagt tggttggatc atattccaga
      361 ccgacaactt gtgagatacg tgcagagtcg ggaacggcag atacacctgc attaccgatc
      421 aacggattga tcttattgcc cttcttgagg aagaggttga agatcttaac gaagatcaca
      481 cctgatgcgg tagcaatgat aaatgacagt gcaccgaggg caaagatctt gatggagtcg
      541 agtgtcagga actcggaagc ctgagtagag gcacctactg tcaaacctaa caggatagtg
      601 ataacgtcaa tcagcggacc gctggctgtg ttagccagac gacgggttac accactttct
      661 ttcaacaggt taccgaagaa cagcataccc agcagaggca gaccggaagg aaccaggaag
      721 caggtcagca acagaccgat aatcgggaaa atcactttct ctgtatgaga aacggcacgt
      781 ggcggtttca tacggataac gcgttcgtgt ttggtggtga gcagacgcat gataggcggc
      841 tgtatcaccg gaactaacgc catataggag taggcggata ccgcaatggc tcccattaag
      901 ttaggtgcca gcttggacga aaggaagata gccgtcggac catctgctcc accgatgata
      961 ccgatagcac cggcctgcat cgggtcaaat cccatttcca atgcgatcat gtatgcaccg
     1021 aagataccaa actgggcagc cgcaccgatc agcatcagct tcggattgga gattagcgcc
     1081 gagaagtctg tcatggcacc gatacctaag aagatgagcg gtggatacca gccggacgtt
     1141 actccctgat acaatatgtt caatacagaa ccttcttcat atataccgac ttttagtccg
     1201 gcgtccatat tgaaaggtat attaccgatc agaataccga atccgatagg aattaacaac
     1261 atcggctcga actctttggc tacagctaag taaataaagc ctaaaccgat aatgatcata
     1321 gcaatatgtc cacctgtcgc gttggcaaat cccgtgtagg tccagaaatc ggcaaggtta
     1381 tttcctaaaa agttaataaa atctcccata ttattcaata attacgaggt cattaccttc
     1441 aagaacagaa tctcccttgt tgacattgat ggcagtcact ttaccgtctt tgtctgcatt
     1501 gatattgttt tccatcttca tggcttccaa tataatgata gtctgtcctc ttttcactgt
     1561 atcacctaca tttactttga tgtcaaggat aacgcctggc agtggggact taacgcctga
     1621 tttgccggta gaaggagcag ccggttttac taccggtgtg gtaggagcag ccggtgagtt
     1681 aggcataggg cgtactactg ccggtttggg agtagctttc ggttgtttct ccatttctac
     1741 tttgtaatgc gtaccgttca cttctacatg agcgatatta tcttcaatat ctccgatggt
     1801 tactttgtat gagttaccgt tgattttata tttatattct ttcatcgttt tatcttttta
     1861 gggaatgatt tactttctgt taggattttc acgcaaggtg taaatcttcg aactccacgg
     1921 tgaataactg cgcttcacac gagtgatggt cagcaccgtt tcttctacgt cgtgtacctc
     1981 atcctgcatt tcgtgtaatg ccattgaaat agcagcataa acttcacccg gagcctgtga
     2041 aagctctttc gcttcgactt tatcgatgcc tttagccttc atcgcattgc gtttgctcag
     2101 gttgacagca actttaccta ccaccttgaa ggcaatgaag agaagaatca atccgcagaa
     2161 tactacgctc atggctgaaa tagacatacc gataccgact gagtcatgtt cttcgaactt
     2221 ttccatcttg gcattactgt caagggtttt gttgttcgtg ctcggggtta cgtatttgtc
     2281 tttgcttccg ccttttactt cccagtctgc tgctccgtcg cttatgcgtg cataagactg
     2341 gttgggacct aaagttcctg ctggtatgac aacttgatca agtagctttc tgcctgaatc
     2401 aaaaagaccg acccaattgg ctgtttcggg attcagtttg aagctggtat ggaaggttcc
     2461 acgattaggt tcgccatctg cccaaaataa cgcatgttgg cgtggcttta ctaatgtaag
     2521 tatgtcacct tttgggataa aataggttac tgtatcgccc ggctggctgc ttactttcaa
     2581 taaacaagct gctaagtctg cgctaccgta tgatttgttg aatatttcaa tccatgcact
     2641 gtgcaagccg tagtcatcct gaaagttgtt ttgattgtct atcaggactt cattcagcaa
     2701 tagcttattg ttcgactttt gctctccgca ggaagtcaat ccaatcagca acagcagaga
     2761 aaggaatatt ccgattttgg ttttgttcat aatcgttctt gttttaatgt gaaaagttgg
     2821 attacaacgg aatattacca tgtttcttcg ccggattaga cagtttctta gtctgcaact
     2881 gctgcaaagc acggatcacg cggaaacgtg tgttacgggg ttcgatgaca tcatcgatgt
     2941 aaccatactt agctgcatta taagggttgg caaacagttt tgtatattct gcttcttttt
     3001 cggcaaggaa ctgagccgga ttttcctggt ctttggcttc acgcgcgtac aatacttcta
     3061 ctgcacctgc accacccatt acagcgattt cagctgttgg ccaagcatag ttcatgtcac
     3121 cacgaagttg tttacaactc atcacgatgt gagaaccacc gtaagattta cgcaatgtga
     3181 ttgttacttt aggtacagta gcttcaccgt aagcatacag cagtttggca ccatgaagga
     3241 tgacgccatt gtattcctga cctgttcccg gaaggaatcc cggtacgtct accaacgaca
     3301 cgatagggat attgaaagca tcgcagaaac gaacgaaacg tgcgcctttg cgagatgcgt
     3361 tgctgtcgag tacaccggca aggaatttag gctgattggc tacaatacct acagactgac
     3421 cgttgaaacg ggcaaaaccg ataatgatat tcttggcata gtctttctgg atttccagga
     3481 attcgccgtt gtctacgata gcgctgataa cctcgtacat atcatacggt ttgttggggc
     3541 tgtcggggat aatatcgttc agagaatctt ccagacggtc gatcggatct gtgcaatcca
     3601 cgtatggagc ttcttcgagg ttgttttgag gaatatagct cagaagtgtg cggatcaatg
     3661 ccagaccttc ttcttctgtt ttggcagtga aatgagtaac acccgatttg gtagagtgaa
     3721 cgcttgctcc gccgaggttt tcctggctta cgtcttcacc ggttacagtt ttcactactt
     3781 tcggacctgt aaggaacata taagaagtac cttccatcat cagtgtgaag tctgtcagtg
     3841 ccggagaata aacagcaccg ccggcacaag gcccgaagat accggaaatc tgcggaatga
     3901 cacccgaagc gaggatattg cgctggaaga tttctgcgta acctgccaaa gcgttaatac
     3961 cttcctggat acgtgcaccg cccgagtcat tgataccgat acaaggagca cccatcttca
     4021 ttgcctgatc cataatctta cagatcttca gtgacattgt ttccgacagt gaacctgcag
     4081 taacggtaaa gtcctgtgca aaaagatata cgagacgacc ttcgatagta ccgcaaccgg
     4141 ttactacacc atcacccgga tagtgctttt tctccatgcc gaagttcgtg catctgtgct
     4201 caacgaacat gtccatttct tcgaagctac cttcatccaa cagcatggct atacgctcac
     4261 gcgctgtgta tttccctttt tcatgttgct tcgcaattgc tttttcgccg cctccgatgc
     4321 gtgcaacggc acggcgttca ataagctctt taattttttc aagttgatta ctcatgagtt
     4381 cttgttgttt ttttagagtt tatgattagt gttcgcagag ttctgtcagc acacccagtg
     4441 ttgatttcgg gtgaaggaaa gcgatgttca gaccttcggc acctttgcgg ggagccttgt
     4501 caatcagacg gatttctttg ctttctgctt ctgccaaagc attagctacg ccatcttcta
     4561 cggcaaatgc tacgtgatga acacctgcac ctttgttttc aataaattta gcaatggtgc
     4621 tttcggggca agtcggctcc aacaattcga tttttgtttc acctaccttt aaaaaagcgg
     4681 ttcttacttt ttgatcttct actgtttcga tgttgtaaca tttcagaccc aatacgtttt
     4741 cgtagtaagg aagggcttct tcgatgcttt ttacagcaat gcccagatgc tcaatgtgtg
     4801 aaatcttcat aactatattt ttttatatgg tttaattatg tgcttatatg gcataaaaca
     4861 gcacaaagaa agacatttct tgtctaataa agaaatattt ctgcatttaa ttattgggga
     4921 ataaagcata aaaaatgctc cggatgggtg acaaagacgg gttttgtaat cttgagatta
     4981 catttagaca taaaacttga ccagaagatt attcagccat ggccagctga tacggaacca
     5041 gcggcgggta ctgctttgtt tgcctccgaa acggagtacg aaatcacgat aaccatgctt
     5101 gcggaaggga agtcctacat ccatgaactc catgtgacgg aatccccgtt catgggcatc
     5161 ttcaagtgct ttccatactg ccagtatgcc gggtgactgc agtgcatagg tctttcgcat
     5221 tcctcctgaa aaccagataa aagcattttc gccggaatag atgcagacgg agccgccgat
     5281 aatcttttcc ttgtatttta cgatgaatat ttttgcctgt tttcctctga taagcatgct
     5341 gttcatgtgg cggaaaaagt cattggcagg gaaatatctc cgtattcgtg aagaataaac
     5401 tttgtgcagc atccgcgaga attccttaat ctcttccacc gtatgggctt ctactacttt
     5461 ggctccgttt ttgagccctt tccggatctg acggatacgt gatgggctga aacggtcttc
     5521 cgctttctgc gtactatgca gagagttacg gacacgcagc cagttgaccg gaaaaaagtc
     5581 gttctttcgg aagaaacggt aaccgaacat ggaattatcc agattgcgga attcaataag
     5641 aatgcaggtg cgtgatgctt cttgtgtgag atgctccagc atttcaccga aaatttcttc
     5701 ctccttctct ttacttgccg gtagagaagt gtccagaaat tcacctgcac catataccac
     5761 acattgtttg acaagagagg agggaagcca ctttttggtc ttgcgtatgg cggcaagcag
     5821 gcgtgctaca ggtctgcctt cttctgttgc cactatcagt agcggggtat atcccggagt
     5881 cgattcatag atctgaaaca actccttgga atgaaaagta ttggttcccg gtaaatcagg
     5941 aatgtctttt ccgcgataat atgttgttag tttaagtggc atccaaatac aaatttacac
     6001 tttttattct tcattcaaca ataaaaaaga gaatttgttg gcttagccta aaatttgtct
     6061 ttttatcctt tgcatatatt tgaggaaaaa aaggcttgga aaagcgaatt tttgtattat
     6121 tgtcgtcctt tgtgagtaca gaagtaaaat ggaaacgtct atataaaaga ttatgctaat
     6181 tgtattttac taaacaaagg aaaattaata ttaactttaa attaaaacga atgagagaga
     6241 atgcatttgt tgaagcgtgg aagacacagc atagacgcgt ttccatgatt ttagggctga
     6301 ctttattgtg tgccccttct gccatatctg tttatgcaga aaatggtgtg aatgatatta
     6361 ctgtgcaagc cgtcatgcag acaaagacag tgaaaggaac tgttttagat gaaaatggag
     6421 aaccgttgat cggtgtttct attgtggtga aaggtacaag tacaggtacg ataactgatt
     6481 ttgacggtaa gttctccatt aatcttccgg ccggaagtaa agaactggtt gtttcttata
     6541 tcggatataa agaacaggct atcattgtga gcggaaatgc cccgctgaat ataaagatgg
     6601 ttccggatac acaggctttg gatgaggtag tggtcatcgg ttacggtacg gtaaagaaac
     6661 gtgatttgac aggtgcggtt gcttctgtga aatcagagga tatcaccatg aatccgggcg
     6721 tgaatccgat ggatgcgctg caaggtaaaa ttgcaggtct ggatatcact aattcttcag
     6781 gtcaggcagg ttcgtcaccg acagttcagt tgcgtggtac ccgctcttta cagttggatg
     6841 aggatggtaa tatctcttca gatgcattta agccgactta tattatcgat ggtatgccgg
     6901 gtgatattgc taccttgaat cccaatgata ttgaatctat cgaagtactg aaagatgcat
     6961 cttctacagc tatctacggt tcaagtggtg cgaatggtgt tattatcgtg actacgaaag
     7021 gatccaagag tggaaaaccg gtcatcaatt ttaatgctta tgccggaacg actatgggtg
     7081 cccgagttcc taagatgcgt acgggtgact catacattaa ttatataaaa gattcttata
     7141 agcctgtcgg tactactaat gaggaggaaa ttttcggtga aagatacgat gccatcaaaa
     7201 acaaccaatg ggtaaactgg ggagatgaag tattacactc aggtttgaag cagaattata
     7261 gtatttccgt tgccggaggt actgagaaga cgaaagccta tttctcgttg aactatactg
     7321 atgagaagag tatgtatgag aatgatgact ataaagtgta ctctacccgt gtccgtatag
     7381 atcaggaaat caataaatgg atgaatgccg gtattaatgt tcaggcatct ttctccaaca
     7441 agaattcacg taatgccgtt ttggaaagag cattgtttgc caccccgtta ggtactcctt
     7501 ataatgaaga cggctctatc acggaattcc cgattctagg ttcatcatca gacccgaatc
     7561 cgttagcaga cgaacaggat ggagtatata agaataatac taaagcagga agggcttatg
     7621 ttgacgctta tcttgaatgg aaaccggtaa aaggattgtc tgtcaagtca cagcttggag
     7681 gcagttattc tcaatctcgt gccggtaaat ttatgggaga aggctcctat aatgtgttga
     7741 aaggcagtac ggtggcatat ggcgaagcta ccaataagac gggatataat tacaaatggg
     7801 aaaacatagt aacttatcac aatacattta ataaggatca tgacctgacg gttacagggg
     7861 ttacttcctg gaattacaat cagagtgaag aatattatgt ctatggtgaa aacccggcga
     7921 ccaatgatat gttgtggtat gcattgcaga atgctgataa taagaaactg aacagcaaat
     7981 atctgatgtc gaaagggatg ggctttatcg gtcgtgtcaa ctactcatac aaaggtaaat
     8041 acctgttttc tgcttccagt cgttatgaag cggattcccg tttgtcgaaa gacaatagat
     8101 ggaatttatt cccggcagtt tctgtaggct ggagaatctc ggatgaagca tttatggctg
     8161 gtacaaaaag ctggttggat aacttgaaac tgcgtgtagg ctatggtgtt gccggaacta
     8221 ctgccggtat tgctgaatac agttctatgg catctttgga aaatgtgaca acctctttgg
     8281 gaggaatgac tgttccgtca gccaagttta cggnnnnnnn nnntttacgg agtatatcac
     8341 taaccgtaat ctgacatggg aaaagactca tgacttgaat attggtattg acgccagctt
     8401 cctcaataat cgtattgatc tgacggtgga tttgtatcgg acaaaaacaa cggatgtaat
     8461 tctttctcag gcattgccga catctattat gggtaattac acaggtagca ctacttataa
     8521 aatgaacaag aatgctgctg aaacagaaaa tcgcggtatt gaacttgctc ttaatactcg
     8581 taatattgtg aagaaagatt ttacttggag ctcaacagtg acatttaccg ccaacaaaga
     8641 aaaaattaaa tctttgatcg aagggcagga tatgatgttc aatgcaaaaa agggtgatat
     8701 ggtgttcaaa gtcggcgaag gagtcggttc tttctataga tataaagtgt tgggtatctg
     8761 gcaatatagc gaaaaggaaa ctgctgcttt gttcggatgc gaaccgggcg atattaagct
     8821 ggatttacct agtgtgaaga aggacggaaa tggttattat tatatgaatc ctgaaggaga
     8881 gcgcgttgat attacggcag aaaatcctta tggtgtacgt gcggattatg atcgtcaggt
     8941 aataggtcgt aatactccgg actggacatt gggctttaag aataatttca gatacaaaga
     9001 ttttgatttg tctgtcttcc tttatgcacg ttgggggcaa atgatgaact atggtagtgt
     9061 gataggtaaa tattcgccta atccggatta caatattcct acttatttta cttactatga
     9121 caagacgatc gaagcagatc aggatgtctt gttctatgct atcgataaat ccaaggatag
     9181 aagtgcttat gaaggatatg attcgatgta ttatgtggat ggatcattct ttaaacttaa
     9241 aaacgtaaca ttgggttata cgttacccgg taaacttaca aaacgttttg gtatcagtaa
     9301 tctgagagtt tatgcgacaa tgaccaacct gtttacttat tcgccaaaca aatatgtgaa
     9361 gaattacgat ccggaaatga acggaagcat caacttccca ttgtctcgtg attgcatatt
     9421 tggtcttaat ttaactttct aaaaaatagc aatatgaaaa agatatatag tttagttcta
     9481 cttgttgccg gtgttttttc ttggggctct tgcagtcttg atgaagtgaa ccccaacaac
     9541 tcgggtcagt tctccgatgg ttcttataca ttggaaactt ataaggcatt caccaactcg
     9601 tgctatacag ccttgatcaa caacatctat cagagtagtg actatctggt ttgtacggaa
     9661 gcgggtactg atatttggga agaacctaaa tcgggctcca gctatcagcg ttatcatagt
     9721 tataacggta tgaaaaccga tgatagctat tattataaag tgtggcaata ttcttatctg
     9781 tgtatcaaca gctgtaatat tgtgattgac ggagctgaga atgtgacagg ggatgagaat
     9841 gaaatcaatg aatgtgtggc acaggccaga tgtctgcgtg cttactatta tatgaatctg
     9901 gtggagcagt ttggcaatgt
//
