LOCUS       c00049_gnlPro..        15527 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|CDJGHMFE_49.
ACCESSION   c00049_gnlPro..
VERSION     c00049_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-05 13:05:21
            Original ID  :: gnl|Prokka|CDJGHMFE_49
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 15527
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             1..786
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_S11"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg49_1"
                     /sec_met_domain="Peptidase_S11 (E-value: 2e-56, bitscore:
                     180.6, seeds: 11, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LPRPANFPTRPVAIPSSAPRTPRCASACVMDALTGNVLFSHNGLQ
                     RRQVASTQKLVTAMVVMEHGSLDKKVVIQPSDTKADPTKLGFRAGEVYSRRELLNAMMI
                     RSFNDVALALARDTAGSVPRFAQLMNAKARQMGMYNSRFANPNGLPADQYSTAIDMARC
                     AYYVYRNPELRNIICKRQYAFTRANGRTLLLRNTNKLLTQNPWVTGMKTGYTNAAGRCL
                     VSSAGVNGRHVIVVVLGCHPSRIWTESENLIRWALGSAA"
     protocluster    1..15527
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[2041:6520]"
                     /cutoff="10000"
                     /detection_rule="(minimum(2, [Aminotran_5, GCV_H, GCV_T,
                     GDC-P, SoxG]) and GCV_H and GCV_T_C)"
                     /neighbourhood="10000"
                     /product="Glycine_cleavage"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      2042..6520
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(2, [Aminotran_5, GCV_H, GCV_T,
                     GDC-P, SoxG]) and GCV_H and GCV_T_C)"
                     /neighbourhood="10000"
                     /product="Glycine_cleavage"
                     /protocluster_number="1"
     cand_cluster    1..15527
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(minimum(2, [Aminotran_5, GCV_H, GCV_T,
                     GDC-P, SoxG]) and GCV_H and GCV_T_C)"
                     /kind="single"
                     /product="Glycine_cleavage"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..15527
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Glycine_cleavage"
                     /region_number="1"
                     /rules="(minimum(2, [Aminotran_5, GCV_H, GCV_T, GDC-P,
                     SoxG]) and GCV_H and GCV_T_C)"
                     /tool="gutsmash"
     CDS             845..1966
                     /locus_tag="ctg49_2"
                     /transl_table=11
                     /translation="MLQAGIVGLPNVGKSTLFNAVTRTRKAQAANYPFCTIDPNVGMVT
                     VPDPRLQVLSDMSGSEKIIPTLIEFVDIAGLVKGASEGAGLGNQFLANIREVDAIVQVV
                     RCFDNDDIIHELGSVDPLRDIDIINSELILADIATMEKRLSSRERKARSGDKEAKAEVA
                     LITKLLPHLNEGNPALTLEPQLDDDERKLLHSFQLLSDKKSIFACNVNEDELADAISNP
                     DAHPYVSQVKKYVAEHHNAEAIVISARIEEELIDVSEEESREFLESLGVKDSGVSDLIR
                     AVYHLLGLRTYLTTGIKETRAWTIPSGAKAPQAAGVIHTDFERGFIAAEVVHYDDLVSC
                     GGKAGAREHGKLRIEGKEYVVKDGDVIEFRFNV"
     CDS             2042..3127
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Glycine_cleavage: GCV_T_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Glycine_cleavage: GCV_T"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg49_3"
                     /sec_met_domain="GCV_T (E-value: 2.8e-88, bitscore: 285.1,
                     seeds: 72, tool: rule-based-clusters)"
                     /sec_met_domain="GCV_T_C (E-value: 3.5e-24, bitscore: 74.2,
                     seeds: 348, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTDTDVKSTPLAAKHVELGARMVPFAGWNMPVQYTGILDEHKAVR
                     ETCGIFDISHMGQFTVAGGSAAAWLNSMLTNDINKLNVGQGQYSVMLNDRAGVIDDLIL
                     YRMEPETFFVVVNASKIDEDFAWLSAHQPAGVTLENHSDEYVGLAVQGPECGEVFSRVI
                     PGVELPPRNGISRITAEGTDLIICRTGYTGEDGFEFFCPAKEGVKWFEAFLGAGAKPCG
                     LGARDSLRLEMCYPLNGSDLSPDKTPLEAGLGFFCALDTDFIGSDILREQKANGLSRRL
                     AAIEYTGKGAPPRAHYAVHVPGGEAIGELTSGVLSPSLMKGIALAYLPAAHAKVGTELE
                     IDVRGRKFPAVVVKKPFYKKG"
     CDS             3198..3578
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Glycine_cleavage: GCV_H"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg49_4"
                     /sec_met_domain="GCV_H (E-value: 1.9e-48, bitscore: 153.0,
                     seeds: 13, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MHDVPENLLYSKDHEWIEIDGDIGTIGISDHAQAELSDVVFVDLP
                     EVGATVAAGDPVAVVESVKAASDVYTPVSGEILEVNEELSNDPSLINSDPYGAGWLYKI
                     RLDVPTETEDMMNATDYEEYCS"
     CDS             3674..6520
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Glycine_cleavage: GDC-P"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Beta_elim_lyase"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg49_5"
                     /sec_met_domain="Beta_elim_lyase (E-value: 1.4e-10,
                     bitscore: 30.4, seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="GDC-P (E-value: 2.2e-179, bitscore: 586.2,
                     seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNTHSDFASRHIGPQGEERREMLDSLGYRTLDELIADIVPADIRM
                     KAPLDLPAAKSETEALEELRSILRKNKLLKTFIGQGYYGTITPSVILRNVLENPGWYTA
                     YTPYQPEIAQGRLEMLMNFQTMVSSLTGLPVANASLLDEGTAAAEAVTMCRNARPKANT
                     FFVADTCHPQTISVIRTRAAFQGVNIIVGDCSSFDPASIGADLAGVLVQYPDTLGRICD
                     YTDFFSRVHATGALCVVAADLMALTVIREPGAFGADICIGNTQRFGIPMGFGGPHAAYM
                     SCTDALKRRMPGRLIGMSIDTLGRPAYRLALQTREQHIRRDKATSNICTAQVLLAVLAA
                     FYAVYHGQEGLKRIGTEIHLKTKNLYKALTEAGIAIENKNFFDTLLLSVPGQADAMVQK
                     ALEAGYNIRRVDADHAAISLDETATCADIAALASALAGAETSATCDCDAPAWDPVHTRQ
                     TPFCTEKAFNSYHSETEMMRYIRRLESRDLALNEAMIPLGSCTMKLNAASEMIPITWPE
                     ANSLHPFVPADQSEGIREMLSVLSDRLAKITGFAAVSLQPNAGAAGEYAGLLAIRRYQK
                     HAGEGHRNVCLIPTSAHGTNPASSAMAGLKVVPVKCDERGNIDMADLKFQAEAHKDNLS
                     CIMVTYPSTHGVYEQTIKELCDIVHANGGQVYMDGANMNAQVGLTCPGCIGADVCHLNL
                     HKTFAMPHGGGGPGIGPIGVAEHLVPFLPGHLTLGHEEGAVASAAWGSASIAAICWMYL
                     SMMGPDGLREATEMAILNANYIAKKLGHLFPVLYSGNKGLVAHECILDPRQLTHDAGLT
                     VDDIAKRLMDYGFHGPTMSFPVPGTLMVEPTESEPKKELDRFIEAMERIHAEITAIING
                     TADKEDNVLKNSPHTAEMVSADEWRHPYSRSEAAYPVSGLLIHKFWPYVGRVDNVYGDR
                     NLVCTCDTVEEFSKAVEL"
     CDS             6776..7840
                     /locus_tag="ctg49_6"
                     /transl_table=11
                     /translation="MSFFSALTVPGFQQHLSFSREDSAILKGYGILFMIFHHVFGLYAL
                     PAGVDTAWIAPQLTKAAPIFKICVPIFIFITGYAMGWKTNSSPTFGSLIKTGFSHYFKF
                     WKIYFLCLLLAILVSWAFPLPILPSVADMDWKNGLLVVTGLRPCYPDWWYMALFAAATM
                     ALYPICAWITHHIAPVPSMAALLGVSLLLQSTAHIPSLPGIASSFPPFLPCFILGYMCA
                     FLASRLSALSISHSLGAILLLALEILSIHLFSFSKAKTLTVIFLFTLWCLPWITRKLRL
                     TPLLTLLGTYSALMWLNHRFIFGYHFSWDLYGAQSISVVFIVTLVSSLLLAMAMQKLFN
                     RMIPSNPQTQSKTL"
     CDS             complement(7872..8504)
                     /locus_tag="ctg49_7"
                     /transl_table=11
                     /translation="MSDLYEYQAIDGSSKGPVDLVLLLRARNLGRLSNRTLVRKVPGGD
                     WRPLASFIPAMTVMDDDGEPSVLPDLGSESGGADSGWSRKKYWMRVIKAWCRFEGRAGK
                     GELHEVFSRVGVAWLAVAGVPSFAECGFFPSLVPWVELVSPLLYVVLAVLSIPLAATMV
                     RRLHDVGRSGLFLVFLAVPFIGWLLLWYLSHGESRIGENKYGDPPWN"
     CDS             complement(8513..10672)
                     /locus_tag="ctg49_8"
                     /transl_table=11
                     /translation="MKLVSLLSVLLTSLVPCMGASGQATKPAARSVKTSKPNVIFILVD
                     DMGWGDLDSNWSQQKLNGRTVERKNEFKTPALSALAREGIQLRRHYSAAPVCAPARASL
                     LLGVHQGNSRVVRNNRFDQPIEDSHTLGTVMRDAGYDTAAIGKWGVGGGGQSHVPMTAG
                     PHQRGFNYFYGILDHLAGHFHYPSESRDVFEYNGYASNPEWKNIKDQVPQTAYSTDLFA
                     ARAKQWIVDQRKSARKTGKPFFLYLAFPAPHGNLVVPGVPYPSGGGLKGGLQWVKKEGT
                     ESVNTAFDAKAEKNKDTYIHPDNSRFPNDVAKRHSTMIRRVDDAVADLIRLLKDLKIDD
                     NTMIVFTSDNGPHNEGGSDSRHWHGAQNPQFFKSYGMMDGIKRDCWEGGMRVPTLVRWP
                     ARIPKGQISLHPGQFHDWLATLADVAGVPVPARSDGVSLLPTLTGHADQQKPGIVYAEY
                     NFAGKTPEYKDFLGEHKGAQRGQQQIVFVDGLKGLRMGVKDADKDFMIFDTLNDPQESK
                     DLASSKPELQARMKAAALSNRRASLPSKTVFDSALVPAVDVKGTVSPGLRWALYEGDFP
                     WVPDFRQWKKPASAHGVTPSPSVKMNGSDKRGVELTGYVKIPEDGAYTFYLTTDENKGS
                     KAFVRLHGMELIDADKTYEPGAEVSSDLGDRKNPVYLKAGLHPIRIGYVGNSGTASKLV
                     LKWEGPGLPKQEIPASAFSHGKESR"
     CDS             complement(11091..12905)
                     /locus_tag="ctg49_9"
                     /transl_table=11
                     /translation="MTQTSSFSALGISPEILEAIEVLGFDTPSSIQEQAIPAAIGGADI
                     VGLSHTGSGKTLAFAIPALECIDPEERCVQVLALCPTRELAVQICREVDKLALFMDGVS
                     AVPIYGGSSFRPQLDALRRGVQFVVGTPGRVMDLMESGALRLDGLRMLILDEADEMLDM
                     GFLEDIEHIADAMPEAKQTLFFSATMSLEISRLVSRFMKEPVQISIERPTLTVPTIEQV
                     YYEVVFSSRIEVLSRLLDTGKIKMGLVFANTKKVVDDVVDGLTARGYPVDRLHGDMPQM
                     MRERVMDSFRKGSLRLLVATDIAARGLDVDDVDAVVNFELPRDPEDYVHRIGRTARAGR
                     KGKAITFVGRRDFSLMSRIERFIGVKLTPEPVLTAVQVDQLRTESLVDDILERLKPDAV
                     LPEELKEVEAEPEAMAAALFDLLRERTHREVQPIPEDKPARRARRMPQTGEEAESPQKG
                     DSWQHKGDTVTLFMNGGRMIGLRPKDIAGLFYNTVEMEKGAVGDIRIFPKHSLIEVDAS
                     VAPLLLEALATATVCGYEVNVREDKGAPEYSGTPRSSRRNGGFRNSYRGERDRSDRSGF
                     RGNRGGFRSDRGERWGERSRRDDRKKRF"
     CDS             13125..13901
                     /locus_tag="ctg49_10"
                     /transl_table=11
                     /translation="MDKTPNKSQSSLLGIFINILLPVLILDYCSAGPANPLERPEGESF
                     WHIGPVWSLVIALSLPLVYGIRSLAVSRKFDLMSGVGMAGVLLTGVISIFVIGPEGRIH
                     SATPWLFAGKEALIPLILAAAVVVSRSTGTPLLNMFIYTPELFDVRRIEQTVAANGEEQ
                     AYQSLLANSSWILAGTLVASSVGNFFLSLSFMSSVIRQPEAEQQVAYNAAIGSITWWGF
                     LIIGIPILAALVFIMTRLIKQLGRLTGLSRNELLLK"
     CDS             13912..15450
                     /locus_tag="ctg49_11"
                     /transl_table=11
                     /translation="MRLHTSCILAAAIALNAAWADAPRFDRIFGSHMVLPHGKNIPVSG
                     TAAPNREITVTFGNTALKTKTDSKGKWSVTLPPMPPCGTGQTLAAVQNGDSAKLEDVLV
                     GEVWLASGQSNMLFRLNQTTTAKEDIAASGDDQLRLLNNIPQAHTNNAPYSGKDFDAVT
                     TDNFYKGQWAASSPSTSGPMTAVGYYFGKKLREGLGIPVGIIHSSLGGSEIAAWLPRQV
                     INTNNSFRTLRGNHWLDSPLISDWVRGRARKNISPRLNQGSPDHPYKPAFLYESGIAWT
                     TPLPITGVIWYQGESDAEIIDNAQNGMLLKTMISSWRKAFRNPEMPFVMIQLPRINDPS
                     KIRAGWPEFREMQDTVAKTVPQVYSVNTIDLGSTNADVHPPFKRPVGERAGNTALNKVY
                     GKKVPCEGPAFKAFKTSGSSILVQMEQAAGLTTTDGKKPAQFEIAGTDGIYHPATAEIT
                     NRKGGTAVIRLSSPEVKSPKNARYCWNRFVTPNLVNGNQLPARPFRTDTPVLKK"
ORIGIN
        1 ctcccccgac cggccaattt ccccacacgt cccgtagcca tcccctcaag cgccccgcgc
       61 acgccccgct gcgccagcgc ctgcgtcatg gacgccctta ccggcaacgt gctcttttcc
      121 cacaacggcc tccagcgccg ccaggtagcc agcacgcaga aactcgtgac ggccatggtc
      181 gtgatggaac acggcagcct ggacaaaaaa gtggtcatcc agccttccga taccaaggcg
      241 gaccccacca aactgggatt ccgggcgggg gaagtctatt cacgccgcga actgctcaat
      301 gccatgatga tccgcagttt caacgacgta gccctggctc tggcccgcga tacggcgggt
      361 tccgttcccc gtttcgccca gttgatgaat gccaaagccc ggcagatggg catgtacaac
      421 tcacgcttcg ccaatcccaa cggcctcccg gcggatcaat attccactgc cattgacatg
      481 gcccgctgcg cctattacgt gtaccgcaac ccggaactgc gcaatattat ctgcaaacgc
      541 caatatgcct ttacccgcgc caacggcaga acgcttctgc tgagaaacac caacaagctg
      601 ctcacccaga acccctgggt taccggaatg aaaaccggat acacgaacgc cgccggacgc
      661 tgcctggttt cctcagccgg cgtcaacggg cgccatgtca tcgtcgtcgt cctcggctgc
      721 catccgtccc gtatctggac ggaatcggaa aacctgatca gatgggctct gggatccgcc
      781 gcataaatgc ccgtcggcaa ttggtatttg actttcacgg cgtgacccgc tatcagtcct
      841 gcctatgtta caggcaggta ttgtaggtct ccccaacgtc ggcaaatcca ctttattcaa
      901 tgcggtcacc cggacgcgca aggcccaggc ggccaactat cccttctgca ccattgaccc
      961 gaacgtgggt atggtaacag tcccggatcc ccgcctgcag gttctttccg acatgtccgg
     1021 ttctgaaaaa atcatcccca cgcttattga attcgtggat attgccggtc tggtcaaggg
     1081 agcctcggaa ggagccggcc tgggcaacca gtttctggcg aacatccgtg aagtggacgc
     1141 catcgtgcag gtagtccgct gctttgacaa tgatgatatt atccatgaac tcggttccgt
     1201 ggatcctctg cgcgacattg acatcatcaa ctcggaactc attctggcgg atatcgccac
     1261 catggaaaag agactctctt cccgcgaacg caaggcacgc agcggcgaca aggaagccaa
     1321 ggccgaagtg gccctcatca ccaaactcct gccccacctg aacgaaggca atcccgccct
     1381 cacccttgaa ccgcagctgg acgacgacga acgcaagctg ctccattcct tccagctgct
     1441 ttcggataaa aaaagcattt tcgcctgcaa tgtcaatgaa gacgaactgg cggacgccat
     1501 ctccaacccg gacgcccatc cctacgtctc ccaggtgaaa aaatacgtag cggaacacca
     1561 taacgcggaa gccattgtca tctccgcccg gattgaagag gaactcatcg acgtctcgga
     1621 ggaagaatcc cgcgaattcc tggaatccct gggtgtgaag gattccggcg tttccgacct
     1681 tatccgcgcc gtgtaccacc ttctgggcct gcgcacctac ctcaccacgg gaatcaagga
     1741 aacgcgggcc tggaccattc cgtccggggc aaaagcacct caggcggccg gcgttatcca
     1801 cacggacttt gaacgcggtt ttatcgccgc agaggtagtg cactacgacg acctggtttc
     1861 ctgtggcggc aaggccggag cgagggaaca cggcaagctg cgcatcgaag gaaaagaata
     1921 tgtcgtcaaa gacggggacg tcatcgaatt ccgcttcaat gtctagacgg aagcgttacc
     1981 ggaattccat tgacttttac tgatataagg ggcagattgc tcacaacctt cacatcgcct
     2041 catgactgat acagacgtca aatccacccc cctggcagct aaacacgttg aactgggagc
     2101 cagaatggtt cctttcgccg gctggaatat gccggtgcag tacaccggca ttctggacga
     2161 acacaaagca gtgcgcgaaa cctgcggcat ctttgacatc tcccacatgg ggcagttcac
     2221 ggtagccggc ggttccgctg cggcatggct gaactccatg ctgaccaatg acattaacaa
     2281 actgaatgta gggcaggggc aatactccgt catgctcaat gacagggccg gagtcattga
     2341 cgacctcatc ctgtaccgga tggaaccgga aaccttcttc gtagtggtga acgcctccaa
     2401 gattgatgaa gacttcgcat ggctttccgc ccatcaacct gcaggcgtaa ccctggaaaa
     2461 ccactccgac gaatacgtgg ggctggctgt tcaaggtccc gaatgcggag aagtattctc
     2521 ccgcgtcatc cccggcgtgg aactcccacc ccgcaatgga atctcccgca tcacggcgga
     2581 agggacggat ctcattatct gccgcaccgg ctataccggg gaagatggtt ttgaattctt
     2641 ctgcccggct aaggaaggcg tcaaatggtt tgaagccttt cttggagcag gagccaaacc
     2701 ctgcggcctg ggcgcccggg acagcctgcg tctggaaatg tgctatcctc tgaacggctc
     2761 cgatctctct ccggacaaaa cgcctctgga agccgggctc ggattcttct gcgcgctgga
     2821 tacggacttc atcggttccg atattctccg ggaacaaaaa gccaacggcc tcagccgtcg
     2881 gctggccgct attgaataca ccggcaaggg agctcctccc cgcgcccact atgccgtgca
     2941 cgtccccggc ggagaagcca tcggagaact taccagcggc gtgctctctc cttcgctgat
     3001 gaagggcatt gccctggcct acctgcctgc cgcccatgcc aaggtcggca cggagctgga
     3061 aattgacgta aggggaagga aattcccagc cgtggtcgta aaaaaaccct tttataaaaa
     3121 aggctgacac tacggcgcaa aaataaactg acaaacacct cattttacta cactctcact
     3181 tcaaacaatt acatcttatg cacgacgtac cagaaaatct gctgtattcc aaagatcacg
     3241 aatggattga aattgacggg gacatcggca ccatcggcat ttccgaccat gcccaggccg
     3301 aactctccga tgtcgtcttt gtagaccttc ccgaagtagg cgccaccgtc gcagccggcg
     3361 accctgtcgc tgtcgtggaa tctgtcaaag ccgccagcga cgtgtacacc cccgtttcag
     3421 gagaaatcct ggaagtgaac gaagagcttt ccaatgatcc gtccctcatt aactccgacc
     3481 cttacggcgc aggctggctg tacaaaatcc gcctggacgt tcccacggaa acggaagata
     3541 tgatgaacgc cacggattac gaggaatact gctcctgaac cattcttccc tcccccgccc
     3601 cggtgattcc atcccggggc attttgtttg gcccgttccg cggccggacg ctattaccag
     3661 ccagagatac cacatgaata cccactcaga ttttgccagc cggcacatcg gcccccaggg
     3721 ggaagaacgc cgggaaatgc ttgacagcct cggctaccgg acgcttgacg aactcattgc
     3781 ggacatcgtc cccgcagata tccgcatgaa ggccccgctg gacctgcccg cagccaaatc
     3841 ggaaacggaa gccctggagg aactccgttc catcctgcgg aaaaacaagc tcctgaaaac
     3901 cttcattggc cagggctatt acggcaccat cactccctcc gtcatcctcc gcaatgtact
     3961 ggagaacccc ggctggtaca cggcctacac cccttatcaa ccggaaatcg cccagggacg
     4021 gctggaaatg ctcatgaatt tccagaccat ggtctcttcc ctgacagggc tgccggtagc
     4081 gaacgcctcc ctgctggatg aaggcaccgc agcagcagaa gccgtcacca tgtgccggaa
     4141 tgcgcgcccc aaagcaaaca ccttctttgt ggcggacacc tgccacccac agaccatcag
     4201 cgtcatccgt acccgcgccg ccttccaggg cgttaacatc atcgtgggag attgctcctc
     4261 ctttgacccc gcatccatcg gtgcggatct ggccggagtg cttgtccaat atccggacac
     4321 gctcggccgc atctgcgact acacggactt cttttcccgc gtgcatgcca cgggcgcgct
     4381 ctgcgtcgtg gcggcggatc tcatggccct taccgtcatc cgggaacccg gcgccttcgg
     4441 agccgatatc tgcatcggca acacgcagcg cttcggcatc ccaatgggct tcggcggccc
     4501 ccatgccgcc tacatgtcct gcacggacgc tctcaaacgc cgcatgcccg gccgccttat
     4561 cggcatgtcc atagataccc tgggccgccc ggcctaccgc ctggccctgc aaacgaggga
     4621 acagcatatt cgccgcgaca aggcgacctc caacatctgc accgcccagg tgctcctggc
     4681 cgtgcttgcc gccttttacg ccgtatacca cggccaggaa ggcctcaaac gcatcggcac
     4741 ggaaatccac ttgaaaacca aaaacctgta caaggcgctc acggaagccg gcattgccat
     4801 tgaaaacaaa aacttctttg acaccctgct gctgtccgtt cccggacaag cggacgccat
     4861 ggtgcaaaaa gccctggaag ccgggtataa catccgcagg gtggatgccg accacgcagc
     4921 tatctctctg gatgaaaccg caacctgtgc ggatatagcg gcactggcct ccgcccttgc
     4981 aggtgcggaa acatccgcca cctgcgattg cgacgctcct gcctgggatc ccgtccacac
     5041 gcgccagacg cctttctgca cggaaaaggc tttcaactcc taccattccg aaacggaaat
     5101 gatgcgctac atccgccgcc tggaatcccg ggacctggct ctaaatgaag ccatgatccc
     5161 tctgggctcc tgcacgatga agctgaacgc cgcctctgaa atgattccca tcacgtggcc
     5221 ggaagccaac tccctgcatc cctttgttcc ggcggaccag tcggaaggca tccgggaaat
     5281 gctctccgtc ctgtccgacc gtctggcgaa aatcaccggc tttgccgccg tatccctcca
     5341 gcccaacgcg ggcgccgcag gggaatatgc cgggctactg gccatccgcc gctaccagaa
     5401 gcacgccgga gaaggccacc gcaatgtctg cctcattccc acctccgccc acggaacaaa
     5461 tcccgcatcc tccgccatgg ccggcctcaa ggtggtgccc gtcaaatgcg acgaaagagg
     5521 caacatcgac atggcagacc tgaaattcca ggcggaagcc cataaggaca atctttcctg
     5581 catcatggtc acgtacccct ccacgcacgg ggtatatgaa cagacaatca aggaactctg
     5641 cgacatcgtc catgccaatg gcggccaggt gtacatggat ggagccaaca tgaatgccca
     5701 ggtaggtctg acttgccccg gctgcattgg cgcggacgtc tgccacctga acctgcataa
     5761 aacctttgcc atgccgcacg gcggcggcgg tcccggcatc gggcccatcg gcgtagcgga
     5821 acacctcgta cccttcctgc ccgggcacct cacgctgggc catgaagaag gggccgtagc
     5881 gtctgcggcg tggggaagcg cctccatcgc cgccatctgc tggatgtacc tctccatgat
     5941 ggggccggac ggcctcaggg aagccacgga aatggccatc cttaacgcca actacattgc
     6001 caagaaactc ggacatctct tcccggttct ctactccggc aacaaggggc tggtggcgca
     6061 tgaatgcatt ctggatccgc gccagctcac tcatgacgcc ggcctcacgg tggatgacat
     6121 tgccaaaagg ctcatggact acggcttcca cggccccacc atgtccttcc ccgttccggg
     6181 caccctgatg gtggagccga cggaatcgga acccaaaaaa gaactggacc gcttcattga
     6241 agccatggaa cgcattcatg cggaaatcac ggccattatc aacggtacgg cagacaagga
     6301 agacaacgtc ctgaaaaact cgccccatac cgcagaaatg gtctctgccg acgaatggcg
     6361 gcatccctac tcccgcagtg aagcggctta tccggtctct ggtctcctta ttcacaaatt
     6421 ctggccgtat gtaggccggg tggataatgt gtacggagac cgcaatctgg tctgcacctg
     6481 cgacacggtg gaggaattct ccaaggccgt agagttataa aaatctcatc cttcctttca
     6541 aaaaggctgt tccattcatt tggagcagcc tttttcttat gttcaagaat cggatttcta
     6601 atccgaagtc aacactctat tttgagaata aatgggtcat caaaatgaaa ggggaggaaa
     6661 agcagagtag gagaaatgtg cctttttctt ttttaataca tactgctttt atgcttaatt
     6721 gttttctgga tgcgtttgtt tcttcggatt agaaatccgt tgagctaggt ttcagatgag
     6781 ctttttctct gcccttactg ttcctggctt tcaacagcat ctttcttttt ccagggaaga
     6841 ttccgctatc ctcaaagggt atggaattct cttcatgatc tttcatcatg tcttcggctt
     6901 atacgctctg cccgcaggtg tggatacggc atggattgct ccccagctta ccaaagccgc
     6961 tcccatcttt aaaatttgcg tgcccatttt tattttcatc acggggtacg ctatgggatg
     7021 gaaaacaaat tcatccccaa ccttcggttc cctcattaaa acaggctttt cccattactt
     7081 taaattctgg aaaatttatt tcttatgcct ccttctggct attctggttt cctgggcatt
     7141 ccccttgccc attttgccat ccgttgccga catggattgg aaaaatggcc tgcttgtagt
     7201 aacaggattg aggccctgtt atcccgactg gtggtacatg gctcttttcg cggcagccac
     7261 catggccctt tatccaatct gtgcgtggat cacgcatcac attgcgcctg tcccgtccat
     7321 ggcagctctg ctgggagtgt cccttttact tcaaagtacg gcccacattc ccagcctgcc
     7381 gggaatcgcc tcatccttcc ctcctttcct gccctgcttc attctcggct acatgtgcgc
     7441 ctttctggct tcacgcctct ctgctctttc aatttcccac agcttggggg caatcctgtt
     7501 gctggctctt gaaatactat ccatccatct cttcagtttt tcaaaagcca aaaccctgac
     7561 ggttatcttt ctcttcaccc tctggtgtct gccttggata acccggaaac tccgcctcac
     7621 accgctcttg acgctgctgg gaacttattc cgcacttatg tggctgaatc acagattcat
     7681 tttcggctac cacttcagct gggacctcta tggggcccaa agcatcagtg tagtattcat
     7741 cgtgacgctg gtctcctccc ttctgctggc catggccatg caaaaacttt ttaaccggat
     7801 gattccctca aatccgcaaa cgcagtcaaa aactttgtag caactttaca aggtccgaat
     7861 tccaacacct cttaattcca agggggatct ccgtacttat tctctccaat ccggctttcc
     7921 ccatgggata aataccacaa cagcagccac cctatgaagg gaacggccag aaaaaccagg
     7981 aaaaggccgc tcctcccgac atcatgcaga cgccggacca tggtagccgc cagcggaata
     8041 gacagcacgg caagcaccac gtacagcaga ggggaaacca gctcaaccca cggaaccagg
     8101 gacgggaaaa aaccgcattc cgcaaaagag gggactcccg ccacggccag ccacgcaacc
     8161 cccactctgg aaaaaacctc gtgcagctcc cctttcccgg cacggccctc aaaacggcac
     8221 catgccttga tgacgcgcat ccagtacttc ttcctgctcc agccggagtc ggcgcctcca
     8281 gactccgaac cgaggtccgg cagaacggag ggctccccat catcatccat gacagtcatg
     8341 gcggggataa aagaggccag aggcctccag tctccgccgg gaaccttccg gaccaaagtc
     8401 cggttggaca ggcggccgag gttacgggcc cgcagcaaaa gcaccaggtc aaccgggcct
     8461 ttggaagaac cgtcaattgc ctgatactcg tacagatcgc tcatagggac gcttacctgg
     8521 attccttccc gtggctgaag gcggaggcgg gaatctcctg cttgggcaaa ccgggacctt
     8581 cccacttcaa aaccagtttg gaggcagtac cggagttccc cacatagcca atgcggatgg
     8641 gatgaagccc ggctttcaaa taaacgggat tcttccggtc acccagatcg gaggagacct
     8701 cggcccccgg ctcataagtt ttgtccgcgt caatcaattc catgccgtgc agacggacaa
     8761 aagccttgct gcccttattt tcatccgtgg tcagataaaa cgtatatgct ccgtcctctg
     8821 gaatcttcac atatcccgtc agctccacac cgcgcttgtc cgaaccgttc attttcacgg
     8881 atggggaagg cgtcacgcca tgggcggaag caggcttctt ccactggcgg aaatccggta
     8941 cccagggaaa atccccctca tacaaggccc atcgcaaccc gggagaaacg gttcccttca
     9001 catccacggc aggcactagc gcagaatcaa acactgtttt ggaaggaagg gaagcccggc
     9061 gattggacaa agcggcggct ttcatgcggg cctgaagttc cggcttggag gatgcgagat
     9121 ctttgctttc ctgcggatca ttcaaagtat caaaaatcat gaaatccttg tccgcatcct
     9181 tcacccccat gcgcaagcct ttcaatccat ccacaaaaac aatctgctgc tggcctcgct
     9241 gcgctccctt gtgttcgccc aggaaatcct tatactccgg cgttttgccg gcgaaattat
     9301 attcggcata aacaatgccg ggcttctgct ggtccgcatg accggtcagc gtcggcagca
     9361 gggaaacgcc gtcactgcgg gctggaaccg gcaccccggc gacatccgcc agcgtagcca
     9421 gccagtcatg gaactgtcca ggatgcaggc tgatctgccc tttgggaatg cgggcgggcc
     9481 agcgtaccag cgtaggcacg cgcatacctc cttcccagca gtcgcgctta ataccgtcca
     9541 tcatgccata actcttgaaa aactgcggat tttgcgctcc gtgccagtgc ctggagtcgg
     9601 agccaccctc attgtggggg ccattgtcgg acgtgaaaac gatcatcgta ttatcgtcaa
     9661 tcttcaaatc tttcagcaga cggatcaaat cagccacggc atcgtccacg cggcgaatca
     9721 tggtggaatg acgtttggcc acatcattcg ggaaacggga attgtccgga tgaatatagg
     9781 tatccttatt cttttccgcc ttggcgtcaa aagccgtatt cacggattcc gtgccttcct
     9841 tctttaccca ttgcaggcct cctttcaatc cgccgccgga aggataggga acccccggaa
     9901 ccaccagatt gccgtggggc gccggaaaag ccaggtacag gaaaaacggc tttccggtct
     9961 tgcgggcgga cttgcgctgg tccacaatcc actgcttggc gcgggcggca aataaatccg
    10021 tggaataagc cgtctggggc acctggtcct tgatattttt ccactcggga ttggaagcgt
    10081 aaccgttgta ttcgaaaacg tcacgggatt cggaaggata gtgaaaatgc cctgccaaat
    10141 ggtccaggat accgtaaaaa taattgaatc cccgctgatg ggggccggcg gtcatgggca
    10201 catggctctg gcctccgccg cctacacccc atttgccaat ggcagcagta tcatacccgg
    10261 catcacgcat cacggtacca agcgtatggg aatcttcaat aggctggtcg aaacggttgt
    10321 ttctcaccac gcgggaattc ccctggtgca cccccagcag cagggaggcg cgcgccggag
    10381 cgcaaaccgg agcggcggaa taatgacggc gcagctgaat cccctcccga gccagagcgg
    10441 acagggcagg agtcttgaac tcgttctttc tctccaccgt ccggccattc agcttctgct
    10501 ggctccagtt ggaatccaga tcaccccagc ccatgtcgtc caccagaatg aaaataacat
    10561 tgggttttga agttttgaca gaccgggcag ccggcttcgt tgcctgcccg gaagcaccca
    10621 tgcacggaac cagggaagtc agaagaacgg atagtaaaga taccagcttc atgattcaaa
    10681 gaaaatagac tctaaaaaag acgttaaaat aaagcgttat cttacatgaa ttttctcatc
    10741 cctcaagaaa attacgagga aagggcacag aggattgaat cgccagtatt atcggcaaaa
    10801 aacatcaggg aaccagcctt cacagccgga acaactacaa cccgccatac tgcaccaatg
    10861 agcggctttt ctggctgaag ccatgaatgg gagaaaattc ctcctgcatt cccggcgccc
    10921 cggccaccag ccccgcccgg ccatgcttta tcctgaataa aacggcagtc cccccgccgg
    10981 gcagaaaata cagaaaccgg cggaaacagc aatcatgaac cggaacgttc caaaatgtcc
    11041 gcgccaattc cggaacagcg ttaataaccc tgtccggaat agcgaaggca tcagaaacgc
    11101 ttcttcctgt cgtccctgcg ggaacgttcg ccccagcgtt cgccgcggtc actgcggaag
    11161 cccccgcggt ttcccctgaa tccgctccgg tcactgcggt cccgctctcc gcggtaactg
    11221 ttgcggaatc ctccattgcg gcgggaagag cgcggagttc cggaatattc cggagccccc
    11281 ttgtcttcac ggacattaac ttcatagccg cagacggtag ccgtcgccag ggcctccaga
    11341 agcaggggcg ccacggaagc gtccacttct atcagggaat gcttggggaa aatccggata
    11401 tcgcccacgg ctcccttttc catttccacc gtattgtaaa ataacccggc tatgtctttg
    11461 ggccgcaagc caatcatccg gcctccattc ataaacagcg taaccgtatc ccccttatgc
    11521 tgccaggaat cacccttctg cgggctctcc gcctcctccc cggtctgcgg catacgccgc
    11581 gccctgcggg cgggcttgtc ttccggaatg ggctgcactt cccggtgcgt acgttcccgg
    11641 agcaagtcaa acagggccgc agccatggcc tccggctcag cctccacttc cttcaattcc
    11701 tccggcagca cggcatccgg cttgagacgt tccaggatat catccaccag ggactctgtc
    11761 cggagctggt ccacctgaac ggcagtcaac acaggttccg gagtcaactt aacgccgatg
    11821 aaacgttcaa tgcggctcat cagggaaaaa tcacggcgcc ccacaaaagt gatggccttc
    11881 cccttgcggc cggcgcgtgc cgtgcggccg atgcggtgca cgtaatcctc cggatcacgc
    11941 ggcaattcaa aattcaccac ggcatccaca tcgtccacat ccaggccgcg ggcggcaata
    12001 tccgtcgcca ccagaaggcg caggctcccc ttgcggaagg aatccatcac gcgctccctc
    12061 atcatctggg gcatatcccc atgaaggcga tccaccggat aaccgcgggc cgtcagaccg
    12121 tccaccacgt catccaccac ctttttggta ttggcgaaca ccagccccat tttaatcttt
    12181 ccggtgtcaa gcagccggct gagtacctca atccgggagg aaaacaccac ttcgtaataa
    12241 acctgttcaa tggtaggcac cgtcagcgta ggccgttcaa tggaaatctg gacgggctcc
    12301 ttcatgaacc tgctcaccag gcggctgatt tccagagaca tggtagcgga gaaaaacagg
    12361 gtctgcttcg cttccggcat agcgtccgcg atatgttcga tatcttccag aaaccccata
    12421 tccagcatct cgtccgcttc atccagaatc aacatgcgga gaccatccag ccttagcgcc
    12481 ccggactcca tcaggtccat gacgcgtccg ggcgttccca ccacaaactg taccccgcgc
    12541 ctcagggcgt ccagttgcgg gcggaaagaa gagcctccgt aaatggggac ggcggaaaca
    12601 ccgtccatga acaaagccag cttgtccacc tcccggcaaa tctgaacggc cagttcccga
    12661 gtaggacaga gggccagcac ctgaacgcag cgttcctcag gatcaatgca ctccagggcc
    12721 ggaatggcaa aggcaagcgt cttcccggag cccgtatggg acaaccccac aatatcggcc
    12781 cctccgatcg cggcgggaat cgcctgctcc tgaatggagg aaggagtatc gaagccgagc
    12841 acttcgatag cctccagaat ctccggtgaa ataccaagag ccgaaaaaga agatgtttga
    12901 gtcatggggg aaaaatgatc tgtcagagtc acgggagaag ctgaacatta ttccctcccg
    12961 tgtccagcca aaagaacgga agataccgta gatgccacga tttccgcaaa gccgcctgcg
    13021 aataaaaaaa cggctctccc cgcttctggt ctttactgtc acacacgggg ttgcaacttg
    13081 caggggcgca ttcgcatatg gtacaaatat ttccctccga attcatggat aaaacgccaa
    13141 acaaatcaca gtcctccctg ctgggaattt tcatcaacat cctcctcccg gtactgattc
    13201 tggactactg cagcgcaggc cccgccaatc ccctggaacg tccggaggga gaaagtttct
    13261 ggcatatcgg cccggtatgg tctctcgtca tcgccctttc cctcccactc gtctatggca
    13321 tccgttccct ggccgtctcc aggaaatttg acctgatgtc cggcgtaggc atggccggcg
    13381 tgctgctgac gggcgtcatc agcatcttcg tcatcgggcc ggaagggcgc atccacagcg
    13441 ccacaccctg gctgttcgcc ggaaaagaag ccctgatccc cctcatcctg gcggcagccg
    13501 tcgtcgtctc ccgctccacc ggcacccccc tcctcaacat gttcatctac acgccggagt
    13561 tattcgatgt gcgcaggata gaacaaacgg tggccgccaa cggcgaggaa caggcttacc
    13621 agagcctgct ggcaaactcg tcatggattc tggcgggcac attggtcgca tcctccgtcg
    13681 gcaatttctt cctgagcctc tctttcatgt cctccgtcat acgccagccg gaagcggaac
    13741 agcaagtggc ctacaatgcc gctatcggca gcatcacctg gtggggcttc ctgatcatcg
    13801 ggatccccat tctggcagct cttgtcttca tcatgacccg cctgattaaa cagctcggca
    13861 ggctgaccgg gctctcacgg aacgaactcc ttctcaaata atcctcaaac catgcgcctc
    13921 catacttcat gcatcctggc tgccgccatc gcccttaacg cagcgtgggc ggacgccccc
    13981 cggttcgacc ggattttcgg ttcccatatg gtacttcccc acgggaaaaa cattcccgtt
    14041 tccggcacgg ccgcccccaa cagggaaata accgtcactt ttggaaacac tgcactgaaa
    14101 acaaaaaccg attccaaagg aaaatggagc gtcacgctgc ctcccatgcc tccctgcggc
    14161 acaggccaga cgctggcggc cgtgcaaaac ggagactccg ccaaattgga agatgtgctc
    14221 gtgggagaag tgtggctggc ttccggccaa tccaacatgc tgttccgcct gaaccagacc
    14281 acgacggcca aagaagacat agcggcttcc ggagatgacc agctccgcct gctcaacaat
    14341 attccgcaag cccacaccaa caacgccccc tactccggga aagattttga cgccgtcacc
    14401 acggacaact tctataaagg gcaatgggcc gccagctcac cctccacttc aggccccatg
    14461 actgccgtgg gctactattt cgggaaaaaa ctccgcgaag ggctgggcat tccggtaggc
    14521 atcatccact cctccctggg gggctcggaa atcgcagcgt ggctcccccg gcaggtcatt
    14581 aatacaaaca acagtttccg caccctgcgc ggcaaccact ggctggactc cccccttatc
    14641 tccgactggg taaggggacg ggccagaaaa aatatctctc cgcgtctgaa tcagggatct
    14701 ccggaccatc cctacaagcc ggcgttcctt tacgaatccg gcattgcctg gacaacacca
    14761 ctccccatca caggcgtgat ctggtatcag ggcgaatccg atgcggagat cattgacaac
    14821 gcccaaaacg gcatgttgct gaaaactatg atctcctcct ggagaaaagc tttccgtaac
    14881 ccggaaatgc ccttcgtcat gatccagctc ccccgcatta acgatccgtc aaaaatccgt
    14941 gccggatggc cggaattccg cgaaatgcag gacacagtgg ccaaaaccgt cccgcaggtt
    15001 tacagcgtca acaccattga tcttggctcc accaatgccg acgttcatcc tccgttcaag
    15061 cgccctgttg gggaacgtgc aggaaatact gccctgaaca aggtttacgg taaaaaggtc
    15121 ccctgtgaag gccctgcctt caaggccttc aagacctccg gttccagcat cctggtccag
    15181 atggaacaag ctgccggact gaccaccacg gacggcaaga aaccggccca gtttgaaatt
    15241 gccgggacgg acggaattta ccatcccgcc acggcggaaa tcacaaacag gaaaggcggc
    15301 acagccgtta tccgcctctc ctccccggaa gtaaaatccc ccaaaaacgc ccggtattgc
    15361 tggaaccgtt tcgtgacccc caacctggtc aacggcaacc aactccccgc ccgtcccttc
    15421 cggacggaca cacccgttct gaaaaaataa ctcttaccac gccatcattc catgaacctt
    15481 catcttttcc ttgcttccct ggcagccacg ctctcactgg gcattgc
//
