LOCUS       c00027_gnlPro..        13573 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|LNNOMEEI_27.
ACCESSION   c00027_gnlPro..
VERSION     c00027_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-05 13:25:07
            Original ID  :: gnl|Prokka|LNNOMEEI_27
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 42194
            Orig. end    :: 55767
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..13573
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[52194:55708]"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..13514
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
     cand_cluster    1..13573
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /kind="single"
                     /product="Fumarate2succinate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..13573
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Fumarate2succinate"
                     /region_number="1"
                     /rules="(Succ_DH_flav_C and FAD_binding_2 and (Fer2_3 or
                     Fer4_7 or SucD_FumR))"
                     /tool="gutsmash"
     CDS             198..1481
                     /locus_tag="ctg27_27"
                     /transl_table=11
                     /translation="MAITIKKVSTKRELKKFIRFNYRMYKGNPYSVPDLYDDMLNTFNK
                     KKNAAFEFCEADYFLAYRDDKIVGRVAAIINNQANEKWECKNVRFGWIDFIDDPEVSSA
                     LIKTVEEWGKERGMTHIAGPLGFTDFDAEGMLVEGFDQLSTMATIYNHPYYPVHMEKLG
                     FEKDADWVEYKIYIPDAIPDKHKRISELIQRKYNLKIKKYTSGRKIAKDYGQKIFELMN
                     EAYSPLYGYSPLTQRQIDQYVKMYLPILDLRMVTLITDANDELVCVGISMPSLAEALQK
                     SHGRLLPLGWFYLLKALFMKRRAKMLDLLLVAVKPEYQNKGVNALLFSDLIPVYQKLGF
                     IFAESNPELELNGKVQAQWDYFETQQHKRRRAFXXXXXXXXXXXXXXXXXXXXXXXXXX
                     XXXXXXXXNSYGRERIDTCRQQQCSRVH"
     CDS             1426..3303
                     /locus_tag="ctg27_28"
                     /transl_table=11
                     /translation="MEENELIPVDNNNAVEYTDDNIRHLSDMEHVRTRPGMYIGRLGDG
                     AHAEDGIYVLLKEVIDNSIDEFKMQAGKKIEITVEENLRVSVRDYGRGIPQGKLIEAVS
                     MLNTGGKYDSKAFKKSVGLNGVGVKAVNALSSRFEVRSYRDGKVRTAIFSKGNLLSDNT
                     QDTEEENGTYIFFEPDNTLFLNYCFKPEFIETMLRNYTYLNTGLAIIYNGHRILSRNGL
                     VDLLNDNMTATGLYPIIHLKGEDIEIAFTHTGQYGEEYYSFVNGQHTTQGGTHQSAFKE
                     HIARTIKEFFNKNMDYTDIRNGLVAAIAVNVEEPIFESQTKTKLGSTNMVPGGVTVNKY
                     VGDFIKQEVDNFLHKNADVAEAIQQKIQESEKERKAIAGVTKLARERAKKANLHNRKLR
                     DCRIHLNDPKGKGLEEDSCIFITEGDSASGSITKSRDVNTQAVFSLRGKPLNSFGLTKK
                     VVYENEEFNLLQAALNIEDGLDGLRYNKVIVATDADVDGMHIRLLLITFFLQFFPDLIK
                     KGHVYILQTPLFRVRNKKKTIYCYSEEERVNAINELSPNPEITRFKGLGEISPDEFKHF
                     IGKDMRLEQVSLRKTDAVKELLEFYMGKNTMERQNFIIDNLVIEEDLAS"
     CDS             3300..3755
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) CTP_transf_like"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg27_29"
                     /sec_met_domain="CTP_transf_like (E-value: 5.1e-21,
                     bitscore: 66.7, seeds: 65, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRKAIFPGTFDPFTIGHYSVVERALTFMDEIVIGIGINENKNTYF
                     PIEKREEMIRELYKDEPRIKVMSYDCLTIDFAQEVGARFIVRGIRTVKDFEYEETIADI
                     NRKLAGIETILLFTEPELTCVSSTIVRELLTYNKDISQFIPKGMRIS"
     CDS             3825..5408
                     /locus_tag="ctg27_30"
                     /transl_table=11
                     /translation="MNKIKIYVLLACLWAVPALQAQNFGSEAMRKLQMAEFAISHFYVD
                     KVDEDKLVEEAIIKMLAQLDPHSTYSDAEEVKKMNEPLQGNFEGIGVQFQMIEDTLLVV
                     QPVSNGPSEKVGILAGDRIVAVNDSAIAGVKMSTEDIMKRLRGPKGSKVNLTIVRRGVQ
                     DPLLFTVKRDKIPILSLDASYMIQPKTGYIRINRFGATTAEEFKKAMTSLQKQGMKDLI
                     LDLQGNGGGYLNAAIDLANEFLGQKELIVYTEGRTAKRSDFYAKGNGDFRNGRLIILVD
                     EYTASASEIVSGAVQDWDRGIIVGRRSFGKGLVQRPIDLPDGSMIRLTIARYYTPSGRS
                     IQKPYDSTVDYNKDLIERFNHGELMNADSIHFPDSLKAQTKKLGRTVYGGGGIMPDYFV
                     PIDTTLYTDYHRNLVAKGAVIKFTMQFIEGHRKELKNKYKKFESFDEKFVVDDDMLAIL
                     KEIGEKEGVKFNEEQYQKSLPLIKTQLKALIARDLWDMNEYFRVMNTTNESIQKALEIL
                     NSDEYQKKLK"
     CDS             6099..6737
                     /locus_tag="ctg27_31"
                     /transl_table=11
                     /translation="MAIQFELYKTPRPKDEEDKEVYHARVVNFQHIDTEYLAKEIQIAT
                     SLTEGDVKSVLESLSHFMGDRLREGQSVHLDGIGYFQIKLNSQEPITSPKLKANQIKLK
                     ANISFKADVKLKKSVSVVHVERSKLKPHSAVLSNDEIDKLLTNYFKSNPVLTRRDFQGL
                     CGFTPTTAARQIKRLKEEEKKLKNINTYYNPIYVPIPGYYGKAEMKTDE"
     CDS             6765..7553
                     /locus_tag="ctg27_32"
                     /transl_table=11
                     /translation="MKSEEIKELFKQFESIVCEYNKVECWSARELYPLLGYSQWRNFLS
                     ITEKAKDACKNAGENIAYHFADVSKMVILGSGAEREVDNIFLTRYACYLVAQNGDSRKQ
                     EIAFAQNYFAIQTRRAELVEQRLIEYERVQARTKLAETEKLLSGVLYERGVDNQGFAII
                     RSKGDKALFHMDTKMLKRKLGVPDSRPLADFLPTISIKAKDFAAEMTSVNVQQKDLYGQ
                     TAIENEHVDNNVAVRDMLVGRGIFPEQIPANEDIAARVFL"
     CDS             complement(7681..8646)
                     /locus_tag="ctg27_33"
                     /transl_table=11
                     /translation="MLMLRKIVFFFFFLFVGLSLFAQQDYMVSSYVRGNFYNRGRISTE
                     SLRASDDLIFLNVHPNKDGSLSFENPRVFQGKGVTTWEDLIKSVRAKVKGTKVKIRLGA
                     SSGEWKAMVADKAARTTFAKNIKTVLEKNKLDGIDLDFEWAENEKEYKDYSLAILKMRE
                     VLGDKYLFSVSLHPVCYKISKEAIEAVDFISLQCYGPSPVRFPIEKYCSDIQMVLEYGI
                     PKEKLVAGVPFYGVTKDNSKKTEAYFNFVQNGLVTSPAQNEVIYQGDTYVFDGQDNIRI
                     KTRYAKEQKLKGMMSWDLATDLPLSDSRSLLKTMTEELRE"
     CDS             8920..9789
                     /locus_tag="ctg27_34"
                     /transl_table=11
                     /translation="MPRDSFCIQYTNCTGCPKNVENILVYRNLPKGEHIPKDKCTQNCM
                     LFMIKGELLINSEEHPGITLRERQIVLQAIGSKVEILALTDVEYVIYWFNELPLLCEDR
                     YKEMMEQAEAPLTYTPLIMSERLYHLVTSMPEFLAEENPCSKYIDLKCKELVFLITNFY
                     PLPQLGSFFYPISTYTESFHYFVMQNYSKVKNVEEFAHLGGYTTTTFRRLFKNLYGVPV
                     YEWILEKKREGILEDLQHTKMRITEICNRYGFDSLSHFAHFCKDSFGDTPRALRKKAAG
                     GEKIGKVQ"
     CDS             10001..10705
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: SucD_FumR"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg27_35"
                     /sec_met_domain="SucD_FumR (E-value: 2.1e-131, bitscore:
                     426.6, seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MWLSNSSVGRKVVMSVTGIALVLFLTFHMAMNLVAIISADGYNMI
                     CEFLGANWYALVATAGLAALFVIHIIYAFWLTMQNRKARGSERYAVVDKPKTVEWASQN
                     MLVLGLIVIVGLGLHLFNFWAKMQLPELMHNMGMHADTLTLAYAANGAYHIQQTFSSPV
                     YVVLYLVWLFALWFHLTHGFWSSMQSLGWNNKVWINRWKCISNIYSTIVVLGFALVVVV
                     FFVKTLICGGAC"
     CDS             10743..12722
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: FAD_binding_2"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Succ_DH_flav_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1027:FAD binding domain (Score: 202.3; E-value:
                     4.6e-62)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg27_36"
                     /sec_met_domain="FAD_binding_2 (E-value: 2.7e-62, bitscore:
                     202.3, seeds: 62, tool: rule-based-clusters)"
                     /sec_met_domain="Succ_DH_flav_C (E-value: 3.1e-37,
                     bitscore: 118.8, seeds: 739, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIKIDSKIPEGPVAEKWTNYKAHQKLVNPANKRRLDIIVVGTGLA
                     GASAAASLGEMGFRVFNFCIQDSPRRAHSIAAQGGINAAKNYQNDGDSVYRLFYDTVKG
                     GDYRAREANVYRLAEVSNAIIDQCVAQGVPFAREYGGTLDNRSFGGAQVSRTFYAKGQT
                     GQQLLLGAYSALSRQVNVGTVKLYTRYEMQDVVIVDGRARGIIAKNLVTGELERFAAHA
                     VVIATGGYGNAYFLSTNAMGCNCTAAISCYRKGAVFANPAYVQIHPTCIPVHGDKQSKL
                     TLMSESLRNDGRIWVPKKKEDAVKLQKGEIKGSDIPEEDRDYYLERRYPAFGNLVPRDV
                     ASRAAKERCDAGFGVNNTGLAVFLDFSEAINRLGIDVVLQRYGNLFDMYEEITDVNPGE
                     LAKEISGVKYYNPMMIYPAIHYTMGGIWVDYELQTTIKGLFAIGECNFSDHGANRLGAS
                     ALMQGLADGYFVLPYTIQNYLADQITVPRFSTDLPEFAEAEKAVQAKIDKFMSIQGKES
                     VDSIHKKLGHVMWEYVGMGRTAEGLKKGIAELKEIRKEFETNLFIPGSKEGMNVELDKA
                     IRLYDFITMGELVAYDALNRNESCGGHFREEYQTEEGEAKRDDENFFYVACWEYQGDDE
                     KAPVLHKEPLVYEAIKVQTRNYKS"
     CDS             12759..13514
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Fer4_7"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Fer2_3"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg27_37"
                     /sec_met_domain="Fer4_7 (E-value: 2.7e-12, bitscore: 38.5,
                     seeds: 208, tool: rule-based-clusters)"
                     /sec_met_domain="Fer2_3 (E-value: 1.9e-25, bitscore: 80.3,
                     seeds: 38, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 1.2e-06, bitscore: 20.2,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDKNISFTLKVWRQAGPKAKGAFETYQMKDIPGDTSFLEMLDILN
                     EQLISERKEPVVFDHDCREGICGMCSLYINGHPHGPATGATTCQIYMRRFNDGDTITVE
                     PWRSAGFPVIKDLMVDRTAYDKIMQAGGYVSVRTGAPQDANAILIAKPIADEAMDAASC
                     IGCGACVAACKNGSAMLFVSAKVSQLNLLPQGKPEALRRAKAMLSKMDELGFGNCTNTR
                     ACEAECPKNISISNIARLNRDFIIAKLKD"
ORIGIN
        1 ataagatgat tgtttgtggt tttgcgggta atgtttattg cttttcatcg aagtaaactc
       61 cctcttcact atcataatgc ataaactcaa atggtacata agcactaaaa ttatatagat
      121 acagtttttg ccaccccaca cgttgtaatt taaagattat cacgtatctt tgcctgctca
      181 aatcataaat acgagatatg gctattacaa tcaagaaagt ctccacaaag agagaactta
      241 agaaatttat ccgtttcaat tacagaatgt acaagggtaa cccttactct gtgcctgacc
      301 tctatgacga catgctcaac accttcaaca agaagaaaaa cgcagcattc gaattctgtg
      361 aagcagatta tttcctcgca taccgggacg ataaaatagt aggacgtgta gctgcaatca
      421 tcaacaatca ggcgaacgag aagtgggaat gtaaaaacgt tcgtttcgga tggatagact
      481 tcatcgacga tcccgaagta tcatccgcac tcatcaaaac ggtggaagaa tggggaaaag
      541 aacgaggcat gactcacatt gccggtcctc tcggatttac tgatttcgat gcggaaggta
      601 tgttagttga aggattcgac cagcttagta ccatggctac tatctacaac cacccatact
      661 atcctgtaca catggaaaag ttaggcttcg agaaagacgc cgactgggtg gaatacaaaa
      721 tctacatacc ggatgccatt cccgacaagc ataaacgtat ctccgaactg atccaacgaa
      781 aatataacct caagataaag aaatatactt ccggaagaaa aatagccaaa gactacggac
      841 agaagatttt cgagctgatg aatgaagcat acagtcctct ttatggctat tctccgttga
      901 cacagcggca aatcgaccaa tacgtgaaaa tgtatctgcc gatccttgac ttacggatgg
      961 ttacactgat tactgatgcc aatgacgaac tggtctgtgt aggtatctcc atgccatctc
     1021 tcgccgaagc tttacagaaa tcacacgggc gtctgttgcc actcggatgg ttctatctgt
     1081 taaaggcact atttatgaaa cgccgtgcca aaatgcttga tctgctactc gttgcagtga
     1141 aaccggaata tcaaaacaaa ggtgttaacg ctttgttatt ttccgattta attccagttt
     1201 atcaaaaatt aggttttatc tttgcggaaa gcaaccccga actggaactg aacggaaaag
     1261 ttcaggcaca atgggattac tttgagactc aacaacataa gcgccgccgt gcgttcatnn
     1321 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     1381 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnaa cagctatgga agagaacgaa
     1441 ttgatacctg tagacaacaa caatgcagta gagtacactg acgacaacat ccgtcaccta
     1501 agtgacatgg aacatgtacg cacacgcccc ggtatgtata tcggaaggct gggcgacggt
     1561 gcacatgccg aagacggaat ctatgtcctc ctgaaagaag taattgacaa cagtattgac
     1621 gagttcaaaa tgcaagccgg taagaaaatc gagattaccg ttgaagaaaa cctccgtgtc
     1681 agcgtacgcg actacggacg aggcatcccg cagggaaaac tcatcgaagc cgtcagcatg
     1741 ctgaacaccg gtggtaagta cgacagcaag gcatttaaga aaagtgtcgg actaaacggt
     1801 gtcggtgtga aagccgtcaa tgccttgagc tcccgttttg aggtacgcag ttaccgtgac
     1861 ggtaaagtac gtaccgctat tttctcgaaa ggaaacctgc tgagtgacaa tacgcaagat
     1921 accgaagagg aaaacggaac ttacatcttc ttcgaaccgg acaatacatt attcctgaat
     1981 tactgtttca agcctgaatt tattgagaca atgctacgta attacacgta cctcaatacc
     2041 gggcttgcca ttatctataa cggacaccgt atcctgtcgc gtaatggtct ggtagacctt
     2101 ttgaacgaca atatgacggc aaccggactt tacccgatca tccacctgaa aggggaagac
     2161 atcgaaatcg ccttcacgca taccggacaa tacggagaag aatattactc cttcgtcaac
     2221 ggtcagcata ccacccaagg aggtacacat cagagtgctt tcaaggaaca catcgcccgc
     2281 actatcaagg agttcttcaa caagaatatg gactataccg acattcgtaa cggactggtt
     2341 gctgccattg ccgtcaatgt ggaagagcct atctttgaga gtcagacgaa aacgaagctg
     2401 ggttctacca atatggttcc cggcggagtg acagtcaata aatatgtagg cgactttatc
     2461 aaacaggaag tggacaactt cttgcacaaa aatgcggatg tagccgaagc gatacaacaa
     2521 aagatccaag aatccgagaa agagcgtaaa gccattgcag gtgtaaccaa acttgcccgt
     2581 gaacgtgcaa agaaggcaaa cctgcacaac cgcaaattgc gcgactgccg tattcacctc
     2641 aacgacccga aaggaaaagg actggaagaa gactcctgca tctttatcac cgagggggac
     2701 tctgcaagtg gttccatcac caaaagccgt gatgtgaaca cgcaagcagt gttcagtcta
     2761 cgtggtaaac cgctgaattc tttcgggtta accaagaaag tggtctacga gaacgaagaa
     2821 tttaatctgc ttcaggcagc cctgaatata gaagatggct tggacggact acgctacaac
     2881 aaagtcatcg tagcaaccga tgccgatgtg gacggtatgc atatccgcct gctgctaatt
     2941 actttcttcc tgcaattctt ccctgacctt ataaaaaaag gccacgtata tattctgcaa
     3001 acgcctttgt tccgtgtacg caataagaaa aaaacaatct attgttatag tgaagaagag
     3061 cgtgtcaatg caattaacga actaagcccg aatccggaga tcacgcgatt taaaggttta
     3121 ggagagattt caccggacga gttcaagcat ttcatcggta aagacatgcg tctggagcaa
     3181 gtttctttac gaaagacgga cgcagtgaaa gaactacttg aattctacat gggtaaaaat
     3241 accatggaac gacagaactt tattatagat aatctggtta tagaagaaga tttggcatca
     3301 tgagaaaagc aatattcccg ggtacttttg accccttcac catcggacat tattcggtag
     3361 tggaacgtgc actcaccttt atggacgaaa tcgtgatagg aatcggtatc aatgagaaca
     3421 agaatacata ctttcccatt gagaaaagag aggaaatgat tcgggaactt tacaaggatg
     3481 agcctcgtat aaaagtgatg tcctacgact gtctgaccat tgattttgcg caggaagtag
     3541 gagccaggtt tattgtccgc ggtatccgta cagtgaaaga tttcgagtat gaagaaacga
     3601 ttgcggacat caaccgcaaa ctggcaggca ttgaaaccat cctgctcttc acagaaccgg
     3661 aactgacttg cgtcagctcg acgattgtac gcgaattatt gacttataat aaagatatca
     3721 gccagtttat tcccaaagga atgaggataa gttgagagtt gagaaggatg caggcgtatc
     3781 tgtgcccggt tgttaatact cggctattaa tataaagtaa gattatgaat aagattaaaa
     3841 tatacgtcct tttggcttgc ctgtgggcag taccagcctt acaagcccaa aatttcggtt
     3901 ctgaagccat gcgcaagcta cagatggcag agttcgcaat ctcccatttc tatgtagaca
     3961 aagtagatga agacaagttg gtggaagaag ccatcatcaa gatgctggca caactcgacc
     4021 cgcactctac ttactcggac gcagaagaag tgaagaaaat gaacgaacct cttcaaggta
     4081 acttcgaagg tattggagtt cagtttcaga tgattgaaga taccctgtta gtagtgcaac
     4141 ccgtcagcaa cggaccttcc gaaaaagtcg gcatccttgc cggtgaccgt attgttgcgg
     4201 tcaatgacag cgccattgcc ggagtgaaaa tgagtacgga agatattatg aagcgtctgc
     4261 gtggtccgaa aggctctaaa gtcaacctga ctatcgttcg tcgtggcgtg caggatcctt
     4321 tattgttcac agtgaaaaga gataaaatac ctatccttag cctcgatgct tcttacatga
     4381 ttcagcctaa aacaggttat attcgcatca accgcttcgg agcaaccact gccgaagaat
     4441 tcaagaaagc aatgacaagc cttcagaaac aaggtatgaa ggacctgatt ctcgacctgc
     4501 aaggaaacgg aggaggttac ctgaatgcag ctatcgacct tgccaacgaa ttcctggggc
     4561 aaaaagaatt gattgtctac acggaaggac ggactgccaa acgcagtgat ttctacgcca
     4621 aaggaaacgg agatttccgt aatggacgtc ttatcatcct ggtagatgaa tatacggctt
     4681 ccgccagcga aattgtcagc ggtgcagtgc aggattggga cagaggaatt atcgtaggac
     4741 gccgttcttt cggcaaagga ttggtgcaac gccctatcga cttgccggac ggctccatga
     4801 ttcgtttgac tattgcacgc tattatactc catcgggacg ttccatccag aaaccgtacg
     4861 acagtactgt cgattacaac aaggacctga tagaacgttt caaccacggt gaactgatga
     4921 atgctgacag tattcacttc ccggattcac tgaaagcaca aaccaagaag ctaggacgca
     4981 ctgtttatgg cggagggggt atcatgccgg actatttcgt acctattgac actactcttt
     5041 atacggatta tcaccgtaat ctggtagcta aaggagccgt gattaaattc accatgcagt
     5101 ttatcgaagg acaccggaaa gagttgaaaa acaaatacaa gaaattcgaa tcgtttgatg
     5161 aaaagttcgt agtcgatgat gatatgctcg ccattttaaa ggaaatagga gagaaagaag
     5221 gagtgaaatt caatgaagaa caatatcaga agtcgctccc tctcatcaaa acacagctca
     5281 aagcactgat agcccgtgac ctttgggata tgaacgaata tttccgggta atgaatacca
     5341 ccaatgagag tatacaaaag gcgctggaga tactgaattc ggatgagtat cagaagaagc
     5401 tgaaataagg tattcagtaa acaatcataa gacatcattt ttcagttcgg tggacatata
     5461 tactcactat agtgaaaaaa tatctatcat aagtatcatt cattttgata ctcttctcat
     5521 tatcaaagaa ataagtatga cagatagctt ttaaaaaagg tatctatcat acttttacca
     5581 gcaaaaacag gttatctatc atctacaaaa tagccgaata aaggccctat atgcataaga
     5641 tagcttgttt ttgttgaata gtttaattct cccctgccct atatctatca gatagaacaa
     5701 ggcgtataaa tacctcaaac aagcagagat agtttgcttt tctccctgat atagtttatc
     5761 tttgttaccg atatagttca ttcttcatgg ccgtggcgaa ttcctaccac ggccgtggaa
     5821 agatactacc acagccatga agagatctct ccacggccgt gggaaactaa tgataaaggc
     5881 accggaagac aactatccct atgccttagt ccaagaataa aggcaggata acttataaaa
     5941 gccgcttgat aacaaacaaa caacagctat ataacaccct ccccctaagt ccgaagatga
     6001 tcgattagct ttgcaacaac agaaaacaat gtccttatag gcttgcaacg gtaaattaaa
     6061 ggtacgtagt aatgtataag gcaaaaaaca aataaataat ggcaatacaa tttgaattgt
     6121 acaagactcc ccgtcccaag gatgaggaag acaaagaagt gtatcacgca cgtgtagtca
     6181 acttccaaca cattgacaca gaatatttgg caaaagaaat ccagatagca acttctctaa
     6241 ctgaagggga tgtaaagtca gttctcgaat ccctaagtca ttttatgggg gatcgtcttc
     6301 gggaaggaca aagcgtccat ctggatggca tcggttattt ccagataaag ctgaatagtc
     6361 aagaacctat cacttcgccc aaactaaaag cgaatcagat aaaactcaaa gccaacatca
     6421 gctttaaagc ggacgtcaaa ctgaaaaagt ctgtcagtgt tgttcatgtg gagcgaagta
     6481 aactgaaacc ccattcggct gtcctttcaa atgacgagat agacaaattg ctgacaaact
     6541 acttcaagag caaccctgta ttaacccgtc gcgactttca aggattgtgc ggctttaccc
     6601 ctaccactgc cgcacggcaa atcaaacggc tgaaagagga ggagaagaag ttgaagaata
     6661 tcaatactta ttataatccg atttatgtgc cgataccagg atattatggc aaggcggaga
     6721 tgaagacaga tgaataaaag gaacaaacat aatacagaaa taaaatgaaa tcagaagaaa
     6781 taaaagagct atttaagcag tttgagagca ttgtttgcga atacaacaaa gtggaatgtt
     6841 ggagtgcgag agaactttat ccattgttag gatattctca atggcgtaac ttcctgtcta
     6901 tcacagagaa agcaaaagat gcatgtaaaa atgccggaga aaatattgca taccattttg
     6961 ctgacgtcag caaaatggtt atattaggtt caggcgctga aagagaagta gataacatct
     7021 ttctgacccg ttatgcctgc tatctggtag cacaaaatgg agattctcga aagcaagaaa
     7081 ttgcctttgc tcaaaactac tttgcaatac aaacgcgccg tgcagaatta gtagagcaac
     7141 gtttaataga atatgaacgt gtccaagcac gtaccaaact agccgagaca gagaaacttc
     7201 tctcgggtgt tttatatgaa agaggagttg acaatcaagg attcgccatt atacgttcca
     7261 aaggagataa agcactgttt cacatggaca ccaaaatgct aaaacgtaaa cttggcgtac
     7321 ctgatagccg accattggct gattttcttc cgaccatcag cataaaagcc aaagactttg
     7381 ccgcagaaat gacctctgtg aatgttcagc aaaaagacct atacggacaa actgccattg
     7441 aaaatgaaca tgttgacaat aatgtcgcag tcagagatat gcttgttggt agaggcatat
     7501 ttcctgaaca aattcctgca aatgaagata ttgcggcaag ggtatttctc taaagaaaaa
     7561 cgttttaaca cattctttat aaatctgatt tataatcaag gaggggagga acctattaaa
     7621 aagagcctgt tagacagcat ctacaaaaag aatctacaag cagcagtcgt gcgaactaag
     7681 tcattccctc aattcttcag tcattgtttt tagtaatgac ctgctgtcac ttaacggcaa
     7741 atccgtagct aaatcccaac tcatcatacc tttcagcttc tgttcctttg cataacgggt
     7801 tttgatacga atgttatcct gaccgtcaaa cacataagta tctccctgat agatcacttc
     7861 attctgtgca ggactcgtaa ccaatccatt ctgtacaaaa ttgaaataag cctctgtctt
     7921 ctttgaatta tctttggtca ccccataaaa aggaactcct gccaccagtt tttccttcgg
     7981 aataccatac tccaatacca tctgtatatc cgaacaatat ttctctatcg gaaaacgaac
     8041 cggtgaagga ccatagcact gaagtgaaat aaaatcaact gcttcaatag cttccttact
     8101 aatcttataa caaacaggat gcagagatac actgaaaaga tacttgtctc ccaacacttc
     8161 ccgcatcttc aggatagcca aactataatc tttatattct ttctcatttt ctgcccactc
     8221 aaaatcaaga tcaatgccat ccagtttatt cttttccagt acagtcttta tgttctttgc
     8281 aaacgtcgta cgagcggcct tatcggccac catcgctttc cattcgccac tggaagctcc
     8341 caaacgtatt ttcacttttg taccttttac ttttgcacga accgatttaa tcaaatcttc
     8401 ccaagtggtc accccttttc cctgaaatac acgtggattc tcaaatgaca atgatccgtc
     8461 tttattagga tgaacattca agaaaataag gtcgtcactt gcccgcaagc tttctgtaga
     8521 aatacgacca cggttgtaaa aattaccccg cacataagaa ctgaccatat agtcttgctg
     8581 tgcaaacaat gataatccaa caaacaaaaa aaagaagaag aatacaattt ttcttagcat
     8641 tagcataatg attgataatt aaaacgttta gattgcaaaa atacgcatat caaagggaaa
     8701 cagatgttca aaaacaacta taatacttcc aaaaatcaac ataaagtttt ctattcagaa
     8761 atttacaaca gataaatatt gaattctcta acatcatcca aagggataag aataatattt
     8821 gcaggtttct actaaaacat aaataaaaga aagagttcca ttttccgcaa aaaaagccta
     8881 tctttgttcc gttaagataa taaatcacgc ataaaactca tgccaagaga ttcattttgc
     8941 atacaatata ccaactgtac gggatgtcca aaaaatgttg aaaatatcct tgtatataga
     9001 aacttaccta aaggagagca tatccccaag gataagtgta cgcagaattg tatgcttttt
     9061 atgataaagg gcgaattact tatcaatagc gaagagcatc ccggaataac gttacgcgag
     9121 agacaaattg ttttgcaagc tattggctcc aaggtcgaaa tactggcact gacagatgtg
     9181 gaatacgtta tctactggtt caacgaactg cctttgcttt gcgaagaccg atataaggaa
     9241 atgatggaac aggcggaagc tcctttgacc tacactccac tgattatgag tgaaaggctt
     9301 taccaccttg tcaccagtat gcccgaattc ctcgctgaag aaaacccttg cagcaagtat
     9361 atcgacttaa aatgcaaaga actggttttc ttgattacca acttctatcc gctgccccaa
     9421 ctgggttcat tcttctatcc gatcagcact tatacggaaa gtttccacta tttcgtcatg
     9481 cagaattaca gcaaggtgaa gaacgtggaa gaatttgcgc atctgggagg atatacgacc
     9541 actactttcc gccgactatt caaaaacctc tatggtgtgc ccgtatacga atggatactg
     9601 gaaaagaaac gggaaggaat cctggaagac ctacagcaca ccaaaatgcg aatcactgaa
     9661 atctgtaaca gatacggatt cgactctctg tctcatttcg cacacttctg taaagactct
     9721 tttggcgata ccccacgcgc tctacgcaaa aaagcagccg gcggtgagaa aatcgggaaa
     9781 gtacaataaa cagcctcatc ctactaatgt gccaatcagt tgcaccatgc gtacatactg
     9841 gctggcatat tgacacattg gcgcattgat ccattattaa agaattattt ctttaattcc
     9901 ttgctcaatc aatctatttc ccctattttt gcagtctgta agaggtgtaa aacgtcgaaa
     9961 ttttagttct aacaattaaa taatttaaat tcaatcattt atgtggttaa gtaattcatc
    10021 tgtaggaagg aaagtggtga tgagcgttac cggtatcgcc cttgtcctgt ttctaacatt
    10081 tcacatggcg atgaacttgg ttgcaatcat ctcggctgat ggttacaaca tgatttgtga
    10141 gttcctggga gcaaactggt atgcgttagt ggctaccgca ggactagccg ctctttttgt
    10201 gattcacatc atctacgcat tctggctgac aatgcagaat cgcaaagcgc gtggtagcga
    10261 acgctatgca gtggttgaca aaccaaaaac tgtagaatgg gcatctcaaa acatgttggt
    10321 gctgggtctg atcgttatcg taggtcttgg tttgcacctc ttcaacttct gggcaaaaat
    10381 gcagttgccg gaactgatgc acaacatggg catgcacgct gatacactga cgctggctta
    10441 tgccgctaac ggtgcttatc acatccagca gactttctct agcccggttt acgtagttct
    10501 ttacctcgtt tggctgtttg ctttgtggtt ccacctgact cacggtttct ggagctctat
    10561 gcaatcactg ggatggaaca acaaagtatg gatcaatcgt tggaaatgta tttctaacat
    10621 ctattctacg attgttgtac tcggtttcgc actggtagta gtggtattct tcgtgaaaac
    10681 actgatttgt ggcggtgctt gctaaatagt aaattgtaaa tgattaaatt gtaaataata
    10741 ttatgatcaa gatagattca aaaattccag aaggcccggt ggctgagaaa tggaccaact
    10801 ataaagctca ccagaaattg gtgaaccccg ctaataaacg tcgtttggac atcatcgttg
    10861 tgggtacggg tctggcaggt gcttctgccg ctgcttcact tggtgaaatg ggtttcagag
    10921 tattcaattt ctgtattcag gattcccccc gtcgtgcaca ctctatcgct gcacagggtg
    10981 gtatcaatgc tgcgaagaat tatcaaaatg atggtgactc cgtttaccgt ctgttctacg
    11041 atactgtaaa aggtggcgac tatcgtgccc gtgaagctaa cgtatatcgt ctggctgaag
    11101 tgtctaacgc tatcatcgac caatgtgtag cgcaaggtgt tcctttcgct cgcgaatatg
    11161 gcggtacact ggataaccgt tctttcggtg gcgcacaggt atcccgtact ttctacgcta
    11221 aaggccagac tggtcagcag ttgctgctgg gtgcttactc tgcattgagc cgtcaggtaa
    11281 acgtaggtac tgttaaactg tatacccgct acgaaatgca ggatgttgtc atcgttgacg
    11341 gacgtgcccg cggtatcatc gcaaaaaatc ttgtaacagg cgaattggaa cgtttcgccg
    11401 ctcacgctgt agtaatcgct actggtggtt atggtaacgc ttacttcctg tctactaacg
    11461 ctatgggttg taactgtaca gctgctatct cttgctaccg caagggtgct gtattcgcaa
    11521 atcctgcata cgttcagatt cacccgactt gtattccggt acatggcgac aagcagtcta
    11581 agctgacttt gatgtctgaa tctctccgta acgacggtcg tatctgggtt ccgaagaaga
    11641 aagaagatgc tgtaaaactc cagaaaggcg aaatcaaagg aagtgatatt ccggaagaag
    11701 accgcgacta ttatttggaa cgccgctatc cggcattcgg taacctggtt ccgcgtgacg
    11761 ttgccagccg tgccgctaaa gaacgttgcg acgctggttt cggtgtaaac aacacaggtt
    11821 tggccgtatt cctcgacttc tctgaagcta tcaaccgttt gggtatcgac gttgttcttc
    11881 aacgttatgg taacctcttc gatatgtacg aagaaatcac tgacgttaat ccgggcgaac
    11941 tggctaaaga aatcagtggt gtgaaatatt ataacccgat gatgatttat ccggctatcc
    12001 actatacaat gggtggtatc tgggtagact acgaactgca aaccactatc aagggtctgt
    12061 tcgctatcgg tgaatgtaac ttctccgacc acggtgcaaa ccgcctcggt gcttctgcat
    12121 tgatgcaagg tttggctgac ggttacttcg tattgcctta cactatccag aactatctgg
    12181 cagaccagat cactgttcct cgtttctcta ccgatcttcc tgaattcgct gaagctgaaa
    12241 aagctgttca agctaagatc gacaagttca tgagcatcca gggtaaagaa tctgttgatt
    12301 ctatccacaa gaaactgggt catgtcatgt gggaatatgt aggtatggga cgtacggcag
    12361 aaggcctgaa gaaaggtatc gccgaactga aagaaatccg caaggaattc gaaacgaact
    12421 tgtttatccc cggttctaag gaaggtatga acgtagagct tgacaaagca atccgtctgt
    12481 acgacttcat cactatgggt gagcttgttg cttacgacgc attgaaccgt aacgaaagtt
    12541 gtggtggtca cttccgtgaa gaataccaga ctgaagaagg agaagcaaaa cgtgatgacg
    12601 aaaacttctt ctatgtagca tgctgggaat atcaaggtga tgatgaaaag gctccggtat
    12661 tgcacaaaga accgctggta tacgaagcta tcaaggttca gactcgtaac tacaagagct
    12721 aatcggtgaa gttaaacatt taaaagaatt agaagaaaat ggataaaaat atatcattta
    12781 cactgaaggt atggcgccaa gctggtccga aagctaaagg tgcttttgaa acctaccaaa
    12841 tgaaagatat ccccggtgat acttccttcc tcgaaatgct ggatattctg aacgaacagc
    12901 tcatcagcga aagaaaagaa ccggtagtat tcgatcatga ctgccgcgaa ggtatctgcg
    12961 gtatgtgttc tctttacatc aacggacacc cgcacggtcc tgcaacaggt gctactactt
    13021 gccagatcta tatgcgtcgt ttcaacgacg gtgacaccat cactgttgaa ccttggcgct
    13081 cggctggttt ccctgtcatc aaagacttga tggtagaccg tactgcatac gacaagatta
    13141 tgcaagctgg tggttatgta agcgtacgca caggtgctcc gcaggatgct aacgctatcc
    13201 tgatcgcgaa acctatcgct gacgaagcta tggatgctgc ttcttgtatc ggttgcggtg
    13261 cttgtgtagc tgcatgtaag aatggttctg ctatgttgtt cgtttctgcc aaagtcagcc
    13321 agttgaactt gctgccgcaa ggtaaaccag aagctttgcg tcgtgcaaaa gctatgttgt
    13381 caaagatgga tgaactggga ttcggtaact gtacaaacac tcgtgcttgt gaagctgaat
    13441 gtccgaagaa tatttctatc agcaacatcg ctcgcttgaa ccgcgacttc atcatcgcaa
    13501 aattaaaaga ctagaaattg ctagatttca atagcgagag cttaatttga ttaatgacag
    13561 aatcccctgc cgg
//
