LOCUS       c00020_gnlPro..        17275 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|AEKFAAGK_20.
ACCESSION   c00020_gnlPro..
VERSION     c00020_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-05 12:13:44
            Original ID  :: gnl|Prokka|AEKFAAGK_20
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 27752
            Orig. end    :: 45027
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..17275
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[37752:41266]"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..13514
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
     cand_cluster    1..17275
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /kind="single"
                     /product="Fumarate2succinate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..17275
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Fumarate2succinate"
                     /region_number="1"
                     /rules="(Succ_DH_flav_C and FAD_binding_2 and (Fer2_3 or
                     Fer4_7 or SucD_FumR))"
                     /tool="gutsmash"
     CDS             1301..5431
                     /locus_tag="ctg20_20"
                     /transl_table=11
                     /translation="MKTYIAAFFLLLSATFVAAHPYLIQRLGIEQGLSNNYVLSITQDK
                     QGFLWFATEEGLNKFDGTRFITYYKEEQSSSVRSITGNELNEVYADPVQPVIWIATQRA
                     GLNAYNYETQSFSVYQYNPEDPQSLITNDVTHITSSVQAGKGLWVCTYYRGIEYLDIAT
                     GKFTHYNKGTVPALPSEQTWTATEAEDGKLYIGHVEGGLSILSLNDKSVKHFVHDPQNP
                     NSLPGNDVRCIYKDTNGNIWIGTSKGLALFNANTETFTNFHNNPGNIHGALSSYIFSIK
                     QLKDNKLWIATELNGIMILDLQQNQFLLPEQIRFEFIREGDNNYSLSNASARYIFQDSF
                     NNIWIGTWGGGINFISNAPPAFHTWSYSPTQMNESSLSNKVVSSVCDDGQGKLWIGTDG
                     GGINVFENGKRVAIYNKENRELLSNSVLCSLKDSEGNLWFGTYLGNISYYNTRLKKFQI
                     IELEKNELLDVRVFYEDKNKKIWIGTHAGVFVVDLASKKVIHHYDTSNSQLLENFVRSI
                     AQDSEGRFWIGTFGGGVGIYTPDMQLVRKFNQYEGFCSNTINQIYRSSKGQMWLATGEG
                     LVCFPSARNFDYQVFQRKEGLPNTHIRAISEDKNGNIWASTNTGISCYITSKKCFYTYD
                     HSNNIPQGSFISGCVTKDHNGLIYFGSINGLCFFNPDIAINSPQIPPVVITKVRIPGRL
                     TSREKNETAIPISEGEIELTHEQNSFNLTFNVQDYSLANQVEYAYMLKGLENSWYTINE
                     QNSVTFRNIPPGKYEFLVKARLHNQDWSEDTTSLRIHINPPLWLTWWAKLIYILITISI
                     IYTIIHAYKKKIDLESLYTLEKKNHEQEQELNQERLRFYTNITHELRTPLTLILGPLED
                     MQKDTSLPTRQAQKLSVIHQSALRLLNLINQILEFRKTETQNKKLCVCKGNITPLIHEI
                     GLKYKELNQKKAIDFQIQIEKEEMPLFFDKEIITIILDNLISNAIKYTEQGKITLSLYP
                     TTRNGVTYTEIKVSDTGYGISAEALPHVFDRYYQESGKHQASGTGIGLALVRNLVELHE
                     GEIRVESIQNEGSTFYISLLTDNIYPNALHGDSTKQTEEEMISEAVPEDSQNTEPETSK
                     PILLIVEDNEDIQKYIAESFSDSFEVITGSNGEEGKQQALNRIPDIIVSDIMMPVMDGI
                     TLCRQLKEDVRTSHIPVILLTAKDSLQDKEEGYEVGADSYLTKPFSASLLRSRINNLLD
                     SRKKLIAQFQQTGTSHNPNSHLDEKRSIITEALSKLDNEFIEKITQLVEDNLSSEKIDI
                     TYLSDKMCMSGSTLYRKMKALTGLSTNEYIRKVKMQNAERLLLEGKYNISEIAYKIGMN
                     STGYFRQCFKDEFGVSPSDYLKQFTSPTPPPSS"
     CDS             complement(5400..6365)
                     /locus_tag="ctg20_21"
                     /transl_table=11
                     /translation="MLLPRKIVFFLLLFVGLSLYAQQNCFISSYVRGNFYNRGRISAES
                     LRASDDLIFLNVRPNKDGSLSFENPRIFENGKGVTSWEELIKSVRADVKGTKTKLRLGA
                     ASGEWKAMVADEAARVAFAKNIKKILEKNKLDGIDLDFEWAETEKEYEDYSLAILKMRE
                     VLGDKYVFSVSLHPVCYKISKEAIAAVDFISYQCYGPSPVRFPMEKYCSDIQMALAYGI
                     PKEKLVAGVPFYGVTKDGSKKTEAYFSFVQDGLITGPAQNEVTYKGDVYVFDGQNNIRA
                     KTRYAMDQQLKGMMSWDLATDMPLNDSRSLFKTMVEELGR"
     CDS             7332..8246
                     /locus_tag="ctg20_22"
                     /transl_table=11
                     /translation="MEHLYDGVTFPEPENLLDWGPETNGRSFKGQTLEELERRWRIASQ
                     DPDKWWCRYPGLPFSTEGMQRTAARRASYQKFIRDYLRCGATVDDNIGKLLNALDEMNI
                     ADNTIVIYVSDQGYFLGEHGFFDKRMFYEESARMPFVIRYPKKVPAGKRLDDLILNVDF
                     APTLAEFAGVKMENVQGDSFVSNLEGNTPTDWRKEIYYRYWTNHAIRPAHFAIRSDRYK
                     LIFYYARNLDMTDTENFDFTPSWDFYDLQNDPHENHNAYNDPKYAPVIKQMKKDLLRLR
                     KETGDTDGKYPEMQELLEKYYNK"
     CDS             9062..9880
                     /locus_tag="ctg20_23"
                     /transl_table=11
                     /translation="MESTLIHRNLLRGQHIPKDKCTQNCMLFMIEGELLINSDEHPGTT
                     LHEKQFILQAIGSKYEILALTDVSYILFWFNELPLLCENRYREIIDQAEGPLTYTPMVM
                     NPRLFYLINDVAAYLDESTPACGKYIDLKCQEMVYMITNYYPLPQLRAFFYPISTYTES
                     FQYFVMQNYSKAKNVEEFAHLGGYNTTTFRRLFRNLYGVPVYEWMLEKKREGILEDLQH
                     SNMRITEICNRYGFDSLSHLAHFCKDSFGDTPRALRKKAANGEKIGKITD"
     CDS             10001..10705
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: SucD_FumR"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg20_24"
                     /sec_met_domain="SucD_FumR (E-value: 3.9e-131, bitscore:
                     425.5, seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MWLSNSSVGRKVVMSVTGIALVLFLTFHMAMNLVAIISADGYNMI
                     CEFLGANWYALVATAALAALFIIHIIYAFWLTMQNRTARGSERYAVVDKPKTVEWASQN
                     MLVLGIIVIVGLGLHLFNFWAKMQLPELMHNLDMHADTLTLAYAANGAYHIQQTFSCPV
                     YVVLYLIWLFALWFHLTHGFWSSMQSLGWNNKVWINRWKCISNIYSTIVVLGFALVVVV
                     FFVKSLLCGGAC"
     CDS             10743..12722
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: FAD_binding_2"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Succ_DH_flav_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1027:FAD binding domain (Score: 200.6; E-value:
                     1.5e-61)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg20_25"
                     /sec_met_domain="FAD_binding_2 (E-value: 7.4e-62, bitscore:
                     200.6, seeds: 62, tool: rule-based-clusters)"
                     /sec_met_domain="Succ_DH_flav_C (E-value: 1.6e-36,
                     bitscore: 116.1, seeds: 739, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIKIDSKIPEGPVAEKWTNYKAHQKLVNPANKRRLDIIVVGTGLA
                     GASAAASLGEMGFRVFNFCIQDSPRRAHSIAAQGGINAAKNYQNDGDSVYRLFYDTVKG
                     GDYRAREANVYRLAEVSNAIIDQCVAQGVPFAREYGGTLDNRSFGGAQVSRTFYAKGQT
                     GQQLLLGAYSALSRQVNVGTVKLFTRYEMQDVVIIDGRARGIIAKNLITGELERFAAHA
                     VVIATGGYGNAYFLSTNAMGCNCTAAISCYRKGAVFANPAYVQIHPTCIPVHGDKQSKL
                     TLMSESLRNDGRIWVPKKKEDAIKLQKGEIKGSDIPEEDRDYYLERRYPAFGNLVPRDV
                     ASRAAKERCDAGFGVNNTGLAVFLDFSEAINRLGIDVVLQRYGNLFDMYEEITDVNPGE
                     LAKEISGVKYYNPMMIYPAIHYTMGGIWVDYELQTTIKGLFAIGECNFSDHGANRLGAS
                     ALMQGLADGYFVLPYTIQNYLADQITVPRFSTDLPEFAEAEKAVQAKIDKFMSIQGKES
                     VDSIHKKLGHIMWEYVGMGRTAEGLKKGIAELKAVRKEFETNLFIPGSKEGMNVELDKA
                     IRLYDFITMGELVAYDALNRNESCGGHFREEYQTEEGEAKRDDENFFYVACWEYQGDDE
                     KAPVLIKEPLVYEAIKVQTRNYKS"
     CDS             12759..13514
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Fer2_3"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Fer4_7"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg20_26"
                     /sec_met_domain="Fer4_7 (E-value: 2.2e-12, bitscore: 38.5,
                     seeds: 208, tool: rule-based-clusters)"
                     /sec_met_domain="Fer2_3 (E-value: 1.6e-25, bitscore: 80.3,
                     seeds: 38, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 9.7e-07, bitscore: 20.2,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDKNISFTLKVWRQAGPKAKGAFETYQMKDIPGDTSFLEMLDILN
                     EQLISERKEPVVFDHDCREGICGMCSLYINGHPHGPATGATTCQIYMRRFNDGDTITVE
                     PWRSAGFPVIKDLMVDRTAYDKIMQAGGYVSVRTGAPQDANAILIPKPIADEAMDAASC
                     IGCGACVAACKNGSAMLFVSAKVSQLNLLPQGKPEALRRAKAMLSKMDELGFGNCTNTR
                     ACEAECPKNISISNIARLNRDFIIAKLKD"
     CDS             complement(13622..14014)
                     /locus_tag="ctg20_27"
                     /transl_table=11
                     /translation="MDTLNLHSNFDNLLYIGRSVLNNTSSHIQKLFFKKEMCIYEYLYK
                     EEVSKGIEIKIDDVVLVCALEHDKCNKSILYFNDVANIARYIHYCNSNFEYKEELNGWI
                     MSDSYLALSISEDDYEKRFAFIQTLL"
     CDS             14140..14364
                     /locus_tag="ctg20_28"
                     /transl_table=11
                     /translation="MTEIMLDKQETLNEIGTKIRKLRESKNLSIQEFADKLEMEYNNVI
                     RIEKGRTNFTIGTLVKIANSLEVNLKDIV"
     CDS             complement(14542..15948)
                     /locus_tag="ctg20_29"
                     /transl_table=11
                     /translation="MDTSVPFIADESGQPVRHPLNDWYHTPNMERLAKQGICFSTFYAQ
                     SVSSPSRASIMTGQNATRHGVTNWINAESNNRNPFGPPQWNWKGLRKDMPTMPRVLQQA
                     GYKTIHVGKAHFGCMGSEGENPLNIGFDVNIAGSGIGHPGSYYGEWGYGHIKGQKIRAV
                     PDLEKYHGTDTFLSEALTIEANREITKAVEEKRPFYLNMAHYAVHSPFQADKRFLSRYT
                     DPDKNEQARAFATLIEGMDKSLGDIMDQLEKLEIAENTLILFLGDNGGDAPLGDERGYG
                     SSAPLRGKKGTEFEGGMRVPFIAAWAKPEKKSKVQKNLPIEVGSMQTQLGTIMDIYPTV
                     LSVAGCEVPQNYVIDGFDLKKQLSGKVDKKRPESFLMHFPHAHRGSYFTTYRMGDWKLI
                     YYYLPETPKQPKALLYNLKDDPEERNELSSAHPDKCREMIQEMSAQLEKEGALYPVDKQ
                     GNELKPFVYF"
     CDS             complement(16416..17273)
                     /locus_tag="ctg20_30"
                     /transl_table=11
                     /translation="RQHKYMSSICQGTWDCQNCPKAVDNAIIHTTHTRGYHQPARKCED
                     NFILFLIKGELLVNSQEYAGTMLKAGEFILQAIGSKYEMLAMTECECIYYRFIQPELFC
                     DFRFNHIMKDVPSPLIYSPLKIIPELKYFLDGSKSYLSESKVCRDLLSLKRKELAFVLS
                     YYYSDYDLASLVHPLSKYTTTFEYFILQNYKKVKTVEELAQLGGYTVSTLRRIFNNVFH
                     EPVYEWMQARRKEGILDDLNNSEYSISEICYKYGFESLPHFSNFCKKFFGASPRMLRTS
                     KKNV"
ORIGIN
        1 ggcaaggagc atggaagaac gcggcatcac ataacaaaaa cgctcgcata acgtttcccc
       61 tttcagattg accagagata tctgttgcac tccgggcggt agttctttag tcgaaatccg
      121 gaattggcag ttcaattcat cttcaaagtc cagtgtcata catttgtaag gtcgcccctg
      181 agaagataca aaaacagcca gtgtgtcttt cattgcctgt gaactgcggg ctacagtgat
      241 atccaacatt tcccgccggt tatcgattcg gagtacatat ccttgtggaa gagcttccgg
      301 aaggtcaaac tgataagtgg agccttcata atcaattttt gccacacccg ccttttcttc
      361 gggcttatac tcaaagtaac ccatcccgtc atgcaatgaa cggatatgcg ccagttcttc
      421 accactcggc aaaaccactg ttccctctac atcagcagct cctttgtcac ggctggtggc
      481 ttcaaaagct acaatcgaag atatgccttt aaccagttgt ccaccctccg gaaaaaagcg
      541 gactgtaaac ttcttctctt tatccttcgg cctctgtttc atcgaagcgt ccatacgata
      601 ggtagctata ctccgaggag tctcttcatc gctcagccgt ttccgataga cgggtaatac
      661 acgggaaaaa caggaagggt tatcaaaagc aagcatccac tttgtatagg cacgcatttc
      721 ataataaccg gtaaagaagg tattgttcaa aatgatttgt cccgttccct ccccatccgt
      781 aagctgaata atttgccgct ctacgacatt tcccaactgg tccagtaatt ctacatacaa
      841 aggtttgctg atcgtcgtcg gtaagttttg ttcagccgtc actacatacg ctttgaacca
      901 aatcgtatca ccaaggtaat aacttgcatt atccaaatga agactcactt tctcgcgagg
      961 gtacgcatct gcgaagttct gcgcataacg gaaatatcgg gaaaagattg tatcggatga
     1021 ctgcgcataa acgttcgctg tacacaagat gaacagagtg gtaataaaaa atgccttcca
     1081 gcttttatca tgttcgtgta aagaatcaga ttccattttc tgcaagtatt agattcggtt
     1141 atttgattga ttgcaaaatt acagttgttt tattttattc gctgtaaaaa tcatgcagaa
     1201 agggtagaaa atcatgcaat gaatcatttg tctatactaa atacaagatt tatttgtact
     1261 tttgagagtg aatatcaagg aatacataat atctgaaacg atgaaaacat acattgcggc
     1321 tttcttcctc ctgctatccg ccacatttgt ggcagcccac ccttacctca tccaaagatt
     1381 gggaatagaa caaggcttat ccaacaatta tgtattgagt atcacgcagg acaagcaggg
     1441 atttctgtgg ttcgccaccg aagaagggct gaataagttt gacggaaccc gctttatcac
     1501 ctactataaa gaggagcaat cttcttctgt ccggagcatt accggcaacg aactcaatga
     1561 agtgtacgcc gatcccgtgc agcctgtaat ctggatagcc acccagcggg cagggctcaa
     1621 tgcttataat tacgagacgc aaagcttcag cgtctaccaa tataatccgg aagacccgca
     1681 aagtctgatt acgaacgacg tcactcacat tacctcatcc gtacaagccg gtaaagggtt
     1741 atgggtatgt acttattaca gaggtataga gtatctggac atcgctaccg ggaaattcac
     1801 tcattataac aaaggtacag tacccgccct tccctctgag cagacctgga cagccacgga
     1861 ggctgaggat ggcaaactat acatcggaca cgtagaaggc gggttgagca tcctctccct
     1921 gaatgacaaa tccgtgaagc acttcgtcca tgatcctcaa aacccgaaca gtcttccggg
     1981 gaacgatgtg cgttgtatct ataaagatac caacggaaat atatggatcg gaaccagcaa
     2041 aggtctggcc ctgttcaatg ccaatacaga aacatttacc aactttcata acaatccggg
     2101 gaatattcac ggagcattgt caagctatat cttctccatc aagcagctca aagacaacaa
     2161 actctggatt gcaacagaac tgaacggaat catgatactg gacttacagc aaaatcagtt
     2221 tctgctgccc gaacaaatac gctttgagtt tatccgcgaa ggggacaata actacagttt
     2281 gtccaacgcc agcgcacggt atatctttca ggactctttt aataatatct ggatagggac
     2341 ttggggagga ggaatcaatt ttatcagcaa tgctcctccc gcattccata catggagtta
     2401 ttcacccacc caaatgaatg aaagttcact gagcaacaaa gtcgttagca gcgtctgcga
     2461 tgacggacaa ggaaagttgt ggataggaac tgacggagga ggtattaacg tattcgaaaa
     2521 cggaaaacgg gtggccattt acaataaaga aaacagagaa ctcctgtcca actcggtgct
     2581 ttgttcgctg aaagactcgg aaggcaacct atggttcggc acctatctgg gcaacatcag
     2641 ctattacaat acaagactga agaagtttca gatcatcgaa ctggaaaaga atgagcttct
     2701 cgacgtacgc gtcttctatg aagacaagaa taaaaagata tggataggga ctcacgcagg
     2761 ggtgttcgtt gtagaccttg ccagcaagaa ggtgattcat cattatgaca cctccaacag
     2821 ccagttgctg gaaaactttg tacgcagcat tgcccaagac agtgaaggac gtttctggat
     2881 aggaactttc ggaggaggag tcgggatata tacgccggat atgcaactgg tcaggaagtt
     2941 caaccaatac gaaggttttt gttccaatac gattaatcag atataccgga gcagcaaagg
     3001 tcagatgtgg cttgccaccg gtgaggggct ggtatgtttt ccttcggccc gtaattttga
     3061 ctatcaggtt tttcaaagaa aagaaggact gcccaataca cacataagag ctatcagtga
     3121 agataagaac ggcaacatct gggcaagtac caataccggc atcagttgct atatcacctc
     3181 taaaaaatgt ttctatacct acgatcactc caacaacatc ccacaaggaa gtttcatcag
     3241 cggatgcgtt accaaagatc ataacgggct catctatttc ggctctatca acggattgtg
     3301 tttcttcaac cccgatattg ccataaacag tccgcagatt cctcctgtgg ttatcactaa
     3361 agtgagaatt cccggacgac tcacaagtcg ggagaagaac gaaaccgcta ttcccatctc
     3421 cgaaggagaa atagaattga ctcatgaaca aaatagtttt aatcttactt tcaacgtaca
     3481 ggactattca ctggccaacc aggtggaata tgcctatatg ctgaaaggac ttgaaaactc
     3541 atggtatacg atcaacgagc aaaacagcgt caccttccgc aatattcctc ccggcaagta
     3601 tgagtttctg gtaaaagccc gtctgcacaa tcaggactgg tcggaggaca cgacctctct
     3661 caggatacat atcaaccctc ctctctggct gacatggtgg gcaaaactta tttatattct
     3721 gatcactatc agcattattt atactattat tcatgcctat aagaagaaaa tagacctcga
     3781 aagtctctac acgctggaaa agaaaaacca cgaacaagag caagaattga atcaggagcg
     3841 tttacgattc tataccaaca tcactcatga gctgcgcaca ccactcactc tgattctcgg
     3901 tccgctggaa gatatgcaga aagacacgtc actgccgacc agacaggcgc agaaactttc
     3961 tgtcatccac cagagtgccc tccggctgct caacctgatc aatcagattc ttgagttccg
     4021 gaaaacggaa acgcagaaca aaaagctatg tgtttgcaaa ggcaacatta cgcccctgat
     4081 tcatgaaatc ggactcaaat acaaagaact caaccaaaag aaagcgatcg actttcagat
     4141 tcaaatagaa aaagaagaga tgcctctgtt ctttgacaaa gaaatcatca ccattatcct
     4201 cgataatctg atttccaatg ccatcaaata tacggaacag ggaaaaataa ccttgagctt
     4261 gtatcccacc acacgaaacg gggtcactta tacggagatt aaagtcagtg atacgggata
     4321 cggaatctct gcggaagcct tgcctcatgt tttcgaccgt tactatcagg aaagcggcaa
     4381 gcatcaggca tccggcacag gtatcggact ggctttagtc cgaaatcttg tagaactgca
     4441 cgaaggcgaa atccgggtgg aaagcataca gaacgaagga agtactttct atatcagctt
     4501 attaacagac aatatctacc ccaacgcttt gcatggagac tctacgaagc aaacagagga
     4561 ggaaatgata tcagaagctg ttccggaaga ttctcaaaat acggaaccgg aaacgagcaa
     4621 acctatcctg ctgattgtag aagacaatga agatatacag aaatacatcg ccgaatcttt
     4681 ctccgactct ttcgaagtaa tcacaggcag caacggtgag gaagggaaac agcaggctct
     4741 caaccgtatt cccgatatta tagtaagcga tatcatgatg ccggtaatgg atggcatcac
     4801 gctatgccgt caactaaaag aggatgtgcg taccagccac atccctgtca tcctgctaac
     4861 ggccaaagat tcattgcagg ataaagaaga aggatacgaa gtgggagcgg attcttatct
     4921 gaccaagcct ttcagtgctt cactgctgcg aagccgcatc aacaatctgc tcgattcgag
     4981 aaagaaactg attgctcaat tccagcagac cggaacgagt cataacccca attctcattt
     5041 ggatgaaaag cgttccataa tcaccgaggc gctcagcaaa ctggataacg aattcattga
     5101 gaaaatcaca caactggttg aggataacct ttcttcggaa aagatcgata tcacttacct
     5161 gtccgacaag atgtgtatga gcggctctac gctctaccgg aagatgaaag cgctgaccgg
     5221 actttctacg aacgaataca tccggaaagt aaaaatgcag aatgcggaac ggttactcct
     5281 cgaaggaaaa tataatatct cggaaatagc ctataaaata ggaatgaaca gtacaggcta
     5341 cttccgtcaa tgttttaagg atgagtttgg tgtctctcct tcagattatc tgaagcagtt
     5401 cacctcccca actcctccac catcgtctta aacaacgatc tgctgtcatt cagcggcata
     5461 tccgtagcca agtcccagct catcattcct ttgagctgct ggtccatcgc ataacgtgtc
     5521 ttggcacgga tattattttg cccgtcaaag acatacacgt ctcccttata ggttacttcg
     5581 ttttgtgccg gccccgtaat cagcccgtcc tgcacaaaac tgaagtaagc ctcagtcttc
     5641 tttgagccat cttttgtcac gccatagaaa ggaacgcctg ccaccagctt ttcctttgga
     5701 atgccataag ccaacgccat ctgtatatcc gaacagtatt tctccatcgg gaagcgaacc
     5761 ggcgaaggac cgtaacactg ataagaaatg aaatcgaccg cagcaatcgc ctctttacta
     5821 atcttataac acacaggatg cagggatacg ctgaacacat atttatctcc caatacctct
     5881 ctcatcttca gaatagccag actgtaatct tcatactctt tttcagtctc cgcccattca
     5941 aaatccagat cgatgccatc gagcttattc ttttccagta tcttctttat gtttttggca
     6001 aatgcaacac gggccgcctc atctgcaacc atcgctttcc actcgccact ggcagcgccc
     6061 agacgaagtt ttgtctttgt tcctttcaca tccgcacgga cagactttat caattcctcc
     6121 caactagtca ctcctttccc attctcaaag atacggggat tctcaaacga aagcgacccg
     6181 tctttattgg gacggacgtt cagaaaaatc agatcatcac tcgcccttaa actctcggca
     6241 gaaatacgtc cgcgattgta gaaattaccc cgtacatacg aactaatgaa gcagttttgt
     6301 tgcgcataca acgataatcc gacaaacaag agaaggaaaa atacaatttt tcttggtagt
     6361 agcataataa ttgataatta atgggttttg atcgcaaaag taggtacagg caaagaaaac
     6421 aaatgttcaa aaatcactat aatacttcca aaaatcaaca taaagtttct tattgagaga
     6481 tgtaaaacaa aaacatcctt ttaaaaaggg aattaagtgt tttaccggaa tcaattacat
     6541 taaatcgcaa aagttttccg gattataata caaagtgaat aacaatcact atctttaggc
     6601 ataaaatcag ttcatatgat catttatcta catgaaagca accgtctaac ttagactgac
     6661 ttttgaagaa atgcaacatc tatacgtata tgaataaact cgtacttacc ggtctgctgg
     6721 cagccggaac catgacgcac ctgcaaggcg ctcaacctgc cggacaacgc cccaacatcc
     6781 tttttatcct gagtgacgac cacacctccc aagcctgggg catctatggc ggagtactgg
     6841 cagaatatgc ccacaacgcc aacatccgcc ggctggcaaa agaaggggta gtgctcgaca
     6901 actgtttctg caccaactct atctcagcac ccagccgtgc cagtatcctc accggtctat
     6961 acagtcaccg gaacagactg tacacccttg cggactcact ggacacctcc atccccaccc
     7021 ttgccaccct gctacaagcc aacggatacc acaccggact cgtcggcaaa tggcatatcc
     7081 agtcgcaacc gcaaggattc gactactact ccatcttcta cgatcaaggc gaataccgtg
     7141 acccgacttt catagagagc accgacccgt ggcccggcaa ccgccggttc ggcgaacggg
     7201 tgctcggctt ctccaccgac ctcgtcaccg agaaagccat ccgatggatg aaagagcagg
     7261 acggcaacca gcccttcctg atgtgctgcc atttcaaagc aacgcacgaa ccctacgact
     7321 acccgatacg catggagcat ctctacgacg gcgtcacctt ccccgaaccc gaaaacctgc
     7381 tggactgggg accggaaacc aacggccgtt ctttcaaagg acagacactg gaagagctgg
     7441 aacgtcgctg gcgcatcgca tcacaggacc ccgacaagtg gtggtgtcgc taccccggac
     7501 tgccgttcag caccgaaggg atgcaacgga cggccgccag acgtgcttcc taccaaaagt
     7561 ttatccgtga ctacctccgt tgcggcgcta ccgtcgacga caacatcggc aaactcctaa
     7621 acgctctgga cgaaatgaat atcgccgaca ataccatcgt catctacgtc tccgaccaag
     7681 gctatttcct aggcgaacac ggcttcttcg acaaacggat gttttatgaa gaatcggctc
     7741 gtatgccttt cgttatccgt tatccgaaga aggtacccgc aggaaaacgt ctggacgatc
     7801 tgatactgaa tgtcgatttc gcaccgacgc tggcagaatt tgccggagta aagatggaga
     7861 atgtgcaagg agacagcttc gtcagcaacc tggaaggcaa cacgccgacc gactggcgaa
     7921 aagaaatcta ctatcgctac tggaccaatc atgctattcg tcccgcgcac ttcgccatcc
     7981 ggtcagaccg ttacaagctg atcttctatt atgcccgaaa tctagacatg actgatacgg
     8041 agaactttga ctttactccg tcatgggact tctatgactt acagaatgat ccgcacgaga
     8101 atcataatgc atacaacgat ccgaaatatg cacctgtcat caaacagatg aagaaagact
     8161 tattgagact tcgcaaagaa accggagata cggacgggaa atatccggaa atgcaggaac
     8221 tgcttgaaaa atactataat aagtaagtga ctggtacgga aactgaactg tcgcatttat
     8281 aacttgaact taggcagctg ctacaagtga aaaagatagc agttttgccc taacgctctc
     8341 attattcgcg tgtatccctt tattcatcgg catttcaagc attacagcaa gtatggtggc
     8401 agagtgagag caagggtttg ctctcactct gccaccacgg catataggtc gtttatccta
     8461 cattatactt tgatttactg ggtattaaca tctgacgcgt cagctattaa cgattgtcat
     8521 gtcagctatt aataattgag aaatcaggta ttaacagctg agaagtcatc cattattgac
     8581 tgaaaaatga aataatacct ttcgaacgga caggtcaatc agagcaactt atgcggtcaa
     8641 gtgagttgaa tcgagctgtc atatgaacga aatcgacagt tgttccaaga agtttcatta
     8701 cttgaaacag tttgtttcat gccttgaaac acttggtttc aacaggtgga actaatgatg
     8761 aaactacttg ttctgaatat atcatgtaaa gggatgaaga aaatgctgca gatggcagat
     8821 aaaaatgtat taatgtatta aagaacgcca ttcaggagtc cgtgaaactt caaagttgtg
     8881 caaacaaaac caataaagac aatcatatcc ccgtttctgc taaaacataa tggaagaaag
     8941 aattttattt tcacaaaaaa cgactatctt tgtccctgta gacaacgatt cacggataaa
     9001 acccatgtca aaagactcac tttgtgctca acatacagat tgctcaggat gccccaaagc
     9061 gatggaaagt actcttattc acagaaatct gctcagaggg cagcatattc cgaaggataa
     9121 gtgcacgcaa aactgcatgc tctttatgat cgagggcgaa ttgctgatca acagtgacga
     9181 acatcccgga acgacactac acgagaaaca gtttatcctg caagccatcg gctcaaaata
     9241 cgagatactg gcactgacgg acgtatcata catccttttc tggttcaacg aactgccgtt
     9301 gctatgcgaa aaccgctacc gtgaaatcat cgaccaggca gaaggcccgc tgacctacac
     9361 cccaatggtg atgaacccgc gcctgttcta tctcatcaac gacgtagccg cataccttga
     9421 cgaatcgaca cccgcctgcg gcaaatatat cgacctgaaa tgtcaggaga tggtgtatat
     9481 gatcaccaat tactatcccc tgccccagtt gagggctttc ttctacccga tcagcaccta
     9541 tacggaaagt ttccaatact ttgtcatgca gaattacagc aaagcgaaga acgtcgaaga
     9601 attcgcacat ctgggaggct ataacaccac caccttccgc cgtctcttcc gaaacttata
     9661 cggcgtgccc gtctacgaat ggatgctgga gaaaaaacgg gaaggcatcc tcgaagacct
     9721 acagcactct aatatgcgga ttacagagat ttgcaaccgg tatggtttcg actcgctgtc
     9781 ccaccttgca cacttctgca aagactcctt cggagacacc ccgcgcgcct tgcgcaagaa
     9841 agcggccaat ggcgaaaaaa tcggaaagat caccgattaa ggaattattt ctttaattct
     9901 ttggtcaatc aatctatttc ccctattttt gcagtctgta agaggtgtaa aacgtcgaaa
     9961 ttttagttct aacaattaaa taatttaaat tcaatcattt atgtggttaa gtaattcatc
    10021 tgtaggaagg aaagtggtga tgagcgttac cggtatcgcc cttgtcctgt ttctaacatt
    10081 tcacatggcg atgaacttag ttgcaatcat ctcggctgat ggttacaaca tgatttgtga
    10141 gtttttggga gcaaactggt atgcgctggt agctaccgca gcactggctg ctcttttcat
    10201 tattcacatc atctacgcgt tctggctgac aatgcagaat cgcacagcgc gcggtagcga
    10261 acgctatgca gtagtcgaca aaccgaaaac tgtagagtgg gcttctcaaa acatgttggt
    10321 gttaggcatt atcgttatcg taggcctcgg tttgcacctc ttcaacttct gggcaaaaat
    10381 gcagttgccg gaactgatgc acaacctgga catgcacgct gatacactga cgctggctta
    10441 tgcggcaaac ggtgcatatc acatccagca gacattctct tgtccggttt atgtagtgct
    10501 ctacctcatt tggctgtttg ctctgtggtt ccacctgact cacggtttct ggagctccat
    10561 gcaatcactg ggatggaaca acaaggtatg gatcaatcgt tggaaatgta tttctaacat
    10621 ctattctacg attgtagtac tcggtttcgc actcgtagta gtggtattct tcgtgaaatc
    10681 actcctttgt ggcggtgctt gctaaatagt aaattgtaaa tgattaaatt gtaaataata
    10741 ttatgatcaa gatagattca aaaattccag aaggcccggt ggctgagaaa tggaccaact
    10801 ataaagctca ccagaaattg gtgaaccccg ctaataaacg ccgtttggat atcatcgttg
    10861 tgggtacggg tctggcaggt gcttctgctg ctgcatccct cggtgaaatg ggtttcagag
    10921 tattcaactt ctgtattcag gactctccgc gccgtgcaca ctctatcgct gcacagggtg
    10981 gtatcaatgc tgcaaagaat tatcagaatg atggtgactc cgtttaccgt ctgttttacg
    11041 atacagtaaa aggtggtgac tatcgtgcac gtgaagccaa cgtttaccgt ctggccgaag
    11101 tgtccaacgc tatcatcgac caatgcgtgg cacaaggtgt tcctttcgca cgcgaatacg
    11161 gcggtacact ggacaaccgt tctttcggtg gcgcacaggt atcacgtaca ttctacgcta
    11221 aaggccagac cggtcagcaa ctcttgctgg gtgcttactc cgcactgagc cgtcaggtaa
    11281 acgtaggtac ggtgaagttg ttcacccgtt atgaaatgca ggacgttgtg atcatcgacg
    11341 gacgtgcacg cggtatcatc gccaagaact taatcaccgg cgaactggaa cgtttcgctg
    11401 ctcacgccgt agtaatcgct accggtggtt acggtaacgc ttacttcctg tctaccaacg
    11461 ctatgggttg taactgtaca gctgctatct cttgctaccg caagggtgct gtattcgcta
    11521 accccgcata cgttcagatt cacccgactt gtatcccggt acacggtgac aagcagtcca
    11581 aactgactct gatgtccgaa tctctgcgta acgacggtcg tatctgggtt ccgaagaaga
    11641 aagaagacgc tatcaaattg cagaaaggcg aaatcaaggg aagcgatatt cctgaagaag
    11701 accgcgacta ttatctggaa cgccgttatc cggcattcgg taacctggtt ccacgtgacg
    11761 ttgccagccg tgcagctaaa gaacgttgcg acgcaggttt cggtgtgaac aacacaggtc
    11821 tggccgtatt cctcgatttc tctgaagcta tcaaccgcct gggcatcgat gtagtgcttc
    11881 agcgttatgg taacctcttc gatatgtatg aagaaatcac tgacgttaat ccgggcgaac
    11941 tggcaaaaga aatcagtggt gtgaaatatt ataatccgat gatgatttat ccggctatcc
    12001 actacacaat gggtggtatc tgggtagact acgaactgca gactaccatc aagggtctgt
    12061 tcgctatcgg tgaatgtaac ttctccgacc acggtgcaaa ccgcctcggt gcttccgcat
    12121 tgatgcaagg tctggccgac ggttacttcg tattgcctta cactatccag aactatctgg
    12181 cagatcagat tactgttcct cgtttctcta ctgaccttcc ggaatttgcc gaagcagaaa
    12241 aggcagttca ggctaagatc gacaagttca tgagcatcca gggtaaagaa tcagttgatt
    12301 ctatccacaa gaaactgggt cacatcatgt gggaatacgt aggtatggga cgtacggcag
    12361 aaggcctgaa gaaaggtatc gccgaactga aagcagtccg caaggaattc gaaaccaatc
    12421 tgtttatccc cggttctaag gaaggtatga acgttgagct cgacaaggct atccgtctgt
    12481 atgacttcat cactatgggc gagctcgttg cttacgacgc attgaaccgt aacgaaagtt
    12541 gtggtggtca cttccgtgaa gaataccaga ctgaagaagg agaagcaaaa cgtgatgacg
    12601 aaaacttctt ctacgtagct tgctgggaat atcagggtga cgatgaaaag gctcctgtat
    12661 tgatcaaaga accgctggta tacgaagcta tcaaggttca gacccgtaac tacaagagct
    12721 aatcggtgaa gttaaacatt taaaagaatt agacgaaaat ggataaaaat atatcattta
    12781 cactgaaggt atggcgtcaa gcaggcccga aggctaaagg cgcttttgaa acctaccaaa
    12841 tgaaagatat ccccggtgat acttccttcc tcgaaatgct ggatattctg aacgaacagc
    12901 tgatcagcga aagaaaagaa ccggttgtat tcgaccacga ctgccgcgaa ggtatctgcg
    12961 gtatgtgttc tctttacatc aacggacatc cgcacggtcc tgcaacaggt gctactactt
    13021 gccagattta catgcgtcgt ttcaacgatg gtgacaccat cactgttgag ccttggcgtt
    13081 cggccggttt ccctgtcatc aaggacttga tggtagaccg tactgcttat gacaagatca
    13141 tgcaggccgg tggttatgta agcgttcgta caggcgctcc gcaggatgcc aacgctatcc
    13201 tgatcccgaa gcccatcgct gacgaagcta tggatgccgc ttcttgtatc ggttgcggtg
    13261 cttgtgtagc tgcttgtaag aatggttctg ctatgttgtt cgtttctgca aaggtcagcc
    13321 agctgaactt gcttccgcaa ggtaaaccgg aagctctgcg ccgtgcgaaa gctatgttgt
    13381 ctaagatgga tgaactcgga ttcggtaact gtaccaacac ccgcgcttgc gaggctgaat
    13441 gtccgaagaa catctctatc agcaacatcg cccgcctgaa ccgcgacttc atcatcgcta
    13501 aactgaaaga ctaagcgtga gcttgatttg attaatagca taaatccccc gtcggcgtta
    13561 gctggcgggg gattttcttt ttactcatta gcaaaagtat aataaaacga ctcagttaag
    13621 ttcatagtaa agtttgtata aacgcaaatc gcttctcata atcatcctca gatatagata
    13681 aagcaagata actatctgac atgatccacc cattgagttc ttctttatat tcaaaattac
    13741 tgttacagta atgaatgtaa cgtgcgatat ttgctacgtc attaaaataa agaatggact
    13801 tattgcattt atcatgttct aaagcacaga ctaagacaac atcatctatt ttaatttcaa
    13861 tgcctttact tacctcctcc ttatacaagt actcatatat acacatctct tttttaaaga
    13921 ataatttttg aatgtgactg ctcgtattat ttaatacgct tctacctata tatagtaggt
    13981 tgtcaaagtt tgaatgcaaa ttaagtgtat ccatctcatc atttttttta ttgttattac
    14041 tcaactgaat attccattag cattattata tctcaccata caatcatata tgattgcgga
    14101 tatgcaaata taaatacttt cctttgaaaa caatcatata tgacagagat tatgcttgat
    14161 aaacaggaaa ctttaaatga gataggtact aaaattagaa aattacggga aagtaagaat
    14221 ctatctatcc aagaattcgc agataaactt gaaatggagt acaacaacgt tattcgaata
    14281 gagaaaggga gaactaattt cactattggt actcttgtga aaatagccaa ttccctagaa
    14341 gtaaatttaa aggatatagt atagcaattt gagatgcaag gattatacaa ctccttagaa
    14401 cgctaaccta aggagctgta tatatgaagc ataactatta tcaactgaac ttcatatatt
    14461 gactgaaatg tctatgcaat tacatttaaa acaatttgcg gataagacat caatactctt
    14521 gcaaaccaaa atcaatgcca atcaaaagta aacaaaaggt ttcaactcat ttccttgttt
    14581 atccaccgga taaagagctc cttccttctc taattgagca gacatttcct gaatcatctc
    14641 cctgcattta tccggatgtg cggaagaaag ttcatttctt tcttccggat cgtctttcag
    14701 attgtaaagc aaggctttgg gttgtttcgg agtctcggga agataataat aaatcagttt
    14761 ccagtcgccc atgcgatagg tggtgaagta gctgccgcgg tgtgcgtgag ggaagtgcat
    14821 caggaaagac tcgggacgct tcttgtccac cttaccgctc agttgctttt tcagatcgaa
    14881 tccgtctatc acgtagtttt ggggaacttc gcatcctgcc acagacagaa cagtcggata
    14941 gatatccatg attgtgccca actgtgtctg catacttcct acttcaatag gcaagttctt
    15001 ctgtactttg ctcttcttct caggctttgc ccaagctgcg atgaaaggaa cacgcatacc
    15061 accttcaaac tccgtcccct ttttacctct cagcggagcg gaagaaccat agccacgttc
    15121 atctcccaat ggagcatcac caccgttatc tcctaaaaag agaatcagcg tattttcggc
    15181 aatttccagc ttttcgagtt ggtccatgat gtcgcctaat gatttatcca tgccttctat
    15241 caatgtagca aaagctcttg cctgctcgtt cttatccggg tcggtgtagc gtgacaagaa
    15301 acgtttgtct gcctggaaag gtgaatgaac tgcgtaatgg gccatattca gatagaaagg
    15361 tcgtttttct tctacggctt tggtgatctc ccgattcgct tctatagtca gcgcttcact
    15421 caggaaggta tctgtaccgt gatatttctc caggtcagga actgctctaa tcttctgtcc
    15481 cttgatatgc ccgtatcccc attcgccata atagctgccg ggatgtccaa tgccggaacc
    15541 tgcgatattt acatcaaagc cgatattcag cggattctct ccttcgcttc ccatacagcc
    15601 gaaatgtgct tttcctacat gaatggtttt atatccggct tgttgcagga ctctcggcat
    15661 ggtaggcata tcttttctga gacctttcca gttccattgg ggcggtccga aaggattccg
    15721 attgttgctc tcagcattaa tccagttagt gactccatgc ctggtcgcat tctgtccggt
    15781 catgatggaa gctctggaag gggaactcac gctctgtgcg taaaaagtag aaaaacaaat
    15841 accctgttta gccagtctct ccatattcgg ggtatgatac cagtcattca gcggatgacg
    15901 caccggctga ccactctcat ctgcgataaa aggaaccgac gtatccataa gtcccatgtc
    15961 atctacaagg aaaacaataa tattcgggcg ctcctgagct actccgcaaa cggaagatgc
    16021 caaaccaccc aatacacaaa attccttaaa agctcgtttt gttctcatta catagtattt
    16081 atgatttata tcctagttat tgtacgtgcc ataatagatt tcaaactcag actctcttct
    16141 gattacacaa aagagtatta gaaaaatatc ctattatctt tcattcattc agcataatct
    16201 atcatgttat tattctgctt tgaaacctga ttttaattcg ttgaaataaa aagtttaatt
    16261 tccgtatccg ccttatcatg gctttatttg aagtgatctg actttataat aaagatgtat
    16321 tagactggtt ttaaaggaaa cagctagcaa tatacaacaa atgtactaca cccacaaaga
    16381 aaaaaatagt ttttgacttt ctctctgaaa aattatcaga cgttcttctt gcttgttcta
    16441 agcatacgtg gagaagctcc aaagaacttc ttacagaaat tggagaagtg aggcagagac
    16501 tcaaaaccgt atttatagca tatttcggag atactgtact cagagttatt caagtcatcc
    16561 aaaatacctt ccttacgtcg cgcctgcatc cattcgtata ccggttcgtg gaatacatta
    16621 ttgaagatac gccgcaaggt gctgacggta taacctccca gttgagccag ttcttctacc
    16681 gtttttactt tcttatagtt ctgaaggatg aagtattcaa aagtggtggt gtatttcgag
    16741 agtggatgca ccaaactagc caagtcataa tccgaataat agtagcttag cacaaacgcc
    16801 agttctttgc gctttaaaga cagcagatcc cggcagactt tactttcact caaataggat
    16861 ttggaaccat ccaaaaagta tttcaattca ggaattatct ttaaaggaga atagataagc
    16921 ggagaaggta catccttcat gatatgattg aaacggaagt cacagaatag ttccggctga
    16981 ataaaacgat aatagataca ttcgcactcg gtcatcgcaa gcatctcgta ttttgaacca
    17041 atagcctgaa gaataaattc acctgctttc aacatcgtac ctgcatactc ctgactatta
    17101 accaagagct ctccctttat caaaaaaagg atgaaattat cttcacactt ccgggctggt
    17161 tgatggtagc cccttgtatg ggtagtgtga atgatagcat tgtctacggc tttcggacag
    17221 ttctgacaat cccaagtacc ctgacagatt gatgacatat atttgtgttg gcgtt
//
