LOCUS       c00140_gnlPro..        13488 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|AEKFAAGK_140.
ACCESSION   c00140_gnlPro..
VERSION     c00140_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-05 12:13:44
            Original ID  :: gnl|Prokka|AEKFAAGK_140
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 13488
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..13488
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[639:3488]"
                     /cutoff="5000"
                     /detection_rule="(Fer4_7 and TPP_enzyme_C and POR and POR_N
                     and PFOR_II and not (EKR or Fer4_16))"
                     /neighbourhood="10000"
                     /product="porA"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      640..3488
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="5000"
                     /detection_rule="(Fer4_7 and TPP_enzyme_C and POR and POR_N
                     and PFOR_II and not (EKR or Fer4_16))"
                     /neighbourhood="10000"
                     /product="porA"
                     /protocluster_number="1"
     cand_cluster    1..13488
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Fer4_7 and TPP_enzyme_C and POR and
                     POR_N and PFOR_II and not (EKR or Fer4_16))"
                     /kind="single"
                     /product="porA"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..13488
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="porA"
                     /region_number="1"
                     /rules="(Fer4_7 and TPP_enzyme_C and POR and POR_N and
                     PFOR_II and not (EKR or Fer4_16))"
                     /tool="gutsmash"
     CDS             324..605
                     /locus_tag="ctg140_1"
                     /transl_table=11
                     /translation="MEQIDNLKELINQGDVDIAIKQLDQLLQDDSVEKDKDMLYYLRGN
                     AYRKKGDWKQALNNYQYAIDLNPDSPAVQARTMAIDILNFYHKDMYNQ"
     CDS             640..867
                     /gene_functions="biosynthetic (rule-based-clusters) porA:
                     Fer4_7"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_6"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg140_2"
                     /sec_met_domain="Fer4_7 (E-value: 3.7e-13, bitscore: 40.1,
                     seeds: 208, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4 (E-value: 8.4e-09, bitscore: 25.3,
                     seeds: 528, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_2 (E-value: 4e-09, bitscore: 26.5,
                     seeds: 214, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_6 (E-value: 8.7e-09, bitscore: 25.5,
                     seeds: 134, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 1.5e-06, bitscore: 18.8,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAKIKGAIVVDTERCKGCNLCVVACPLDVIALNKEVNMKGYNYAW
                     QVKEDTCNGCSSCAMVCPDGCISVYKVKVE"
     CDS             880..1962
                     /gene_functions="biosynthetic (rule-based-clusters) porA:
                     PFOR_II"
                     /gene_functions="biosynthetic (rule-based-clusters) porA:
                     POR_N"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg140_3"
                     /sec_met_domain="PFOR_II (E-value: 2.9e-28, bitscore: 88.5,
                     seeds: 27, tool: rule-based-clusters)"
                     /sec_met_domain="POR_N (E-value: 3.2e-49, bitscore: 157.9,
                     seeds: 31, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAEEVVLMKGNEAIAHAAIRCGADGYFGYPITPQSEVLETLAELK
                     PWETTGMVVLQAESEVAAINMVYGGAGSGKMVLTSSSSPGVSLKQEGISYIAGAELPCL
                     IVNVMRGGPGLGTIQPSQADYFQTVKGGGHGDYRLIALAPASVQEMADFVALGFELAFK
                     YRNPAIILADGVIGQMMEKVVLPAQKPRRTDAEVIEQCPWAATGKAKGRKPNIITSLEL
                     KPEAMEINNIRFQAKYKQIEENEVRFEEINCEDAEYLIIAFGSMARIGQKAMELAREKG
                     IKVGILRPITLWPFPSKAIAAYADKVKGMLVTELNAGQMIEDVRLAVNGKVKVEHFGRL
                     GGIVPDPDEIVTALEEKIIK"
     CDS             1973..2149
                     /locus_tag="ctg140_4"
                     /transl_table=11
                     /translation="MNPDKIRNVLNILFMILALAAIIVYFVVGKEDFKMFIYVCGAAIF
                     VKLMEFFIRFTNR"
     CDS             2162..2926
                     /gene_functions="biosynthetic (rule-based-clusters) porA:
                     TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg140_5"
                     /sec_met_domain="TPP_enzyme_C (E-value: 1.9e-26, bitscore:
                     82.9, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTKEEIIKPENLVYKKPTLMNDNAMHYCPGCSHGVVHKLVAEVIE
                     EMGMEEKTVGVSPVGCAVFAYNYLDIDWQEAAHGRAPAVATAIKRLWPDRLVFTYQGDG
                     DLACIGTAETIHALNRGENITIIFINNAIYGMTGGQMAPTTLVGMKSSTCPYGRDVELH
                     GYPLKITEIAAQLEGTAYVTRQSVQSVPAIRKAKKAIRKAFENSMNGKGSNLVEIVSTC
                     SSGWKMTPEKSNKWMEEHMFPFYPLGDLKDKE"
     CDS             2946..3488
                     /gene_functions="biosynthetic (rule-based-clusters) porA:
                     POR"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg140_6"
                     /sec_met_domain="POR (E-value: 1.9e-36, bitscore: 115.9,
                     seeds: 86, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKEEIIIAGFGGQGVLSMGKILAYSGLMEGKEVSWMPAYGPEQRG
                     GTANVTVIVSDDKISSPILSKYDTAIILNQPSLEKFESRVKPGGILIYDGYGIINPPTR
                     KDIKVYRIDAMDAANEMNNAKAFNMIVLGGLLQLRPIVTLENVIKGLKKTLPERHHHLI
                     PMNEEAIKKGMELIHEV"
     CDS             3609..5651
                     /locus_tag="ctg140_7"
                     /transl_table=11
                     /translation="MRRILLLYILFSVVGLSAIHAQLNPARQQIDENGRDQYGNQVDPA
                     MIPDKLDSANVEVQGLPPTLYMWRIKNQLGDRTMIPADTTYHHFQNTNLTEGITGHYNY
                     LANLGSPRLSRIFFERRYPEPTIFMESFSSFFIRPTEFNFTNSNVPYTNLTYHKAGNKQ
                     NGEERFKSYFSVNVNKKLAFGFNIDYLYGRGYYNNQNTSYFNAALFGSYIGDRYQVQGI
                     YSNNYLKTNENGGITDDRYITAPEEMAEGRKEYESVNIPTVLNASANRNHDFYVFLTQR
                     YNLGFHRDIPQAENDTMPAKQEFVPVTSFIHTIQVERSRHNFRSDDNVENYYKQTLLDK
                     ENTFVRDSTVYIGVKNTIGIALLEGFNKYAKAGLTAFASHKLSKYSLMSLDPLKQDKYN
                     ETEIYIGGELTKKQGNFLHYHAIGEVGMAGKAIGQFDVKGDIDLNIPLWKDTVSVIARG
                     EISNKLAPFYMRHYHSKHFWWDDDMDKEFRTRIEGELSIANWGTRLRAGVENIKNYTYF
                     NQQALPEQKGGSLQVVSACFNQDFKVGIFHLDNEVIWQKSSDQAVLPLPELSLYHNFYM
                     QFKLAKKVLSVQLGADVRYFTKYDAPAYMPATQQFYLQPEEGKVEIGGYPIVNVYANLH
                     LKRTRFYVMMYHVNQGMSKPNYFLAPHYPINPRVLKFGLSWNFYD"
     CDS             5669..6508
                     /locus_tag="ctg140_8"
                     /transl_table=11
                     /translation="MKTRPKLRLFRYLLPVVIVLALIFSVRYCGKQEKPLGHPRDYAAI
                     AKEGILHVATEYNSISFYVDSDTVSGFHYELIEAFARDKGLKTEITPVMSFDERLRGLS
                     DGRYDVIAYGILATSELKDSLLLTSPIILNKQVLVQRKANGENDSLYIRNQLDLAQKTL
                     HVVKGSPSILRIQNLGNEIGDTIYIKEIEKYGSEQLISLVAHGDIDYAVCDESIARAVV
                     DSLPQVDINTAISFTQFYSWAVSKQSPALLDSLNTWLDKFQKEKEYQKIYRKYYGDK"
     CDS             6951..7472
                     /locus_tag="ctg140_9"
                     /transl_table=11
                     /translation="MELKQFKITVVPLRDKLLNYARRMTDDPSDAEDAVQEVMLKLWNL
                     RQKLDEYRSIEAVAMTMTHHLCMDMWRAKRPDTLSLDRVQAPTPSATPERLLEEKDEFR
                     LMREIIDSLPTLQRTIIRMKDIEEYETEEIAEITGCNAEAIRSNLSRARKKVREVYLQT
                     IQERKRRNKA"
     CDS             7469..7930
                     /locus_tag="ctg140_10"
                     /transl_table=11
                     /translation="MKDIETLLNKYFEGETTCEEERRLRRFFAEGLVPEHLEVYRPMFA
                     FFEAEQKELAEISGKGNAAEMPELAPFEKKTKTVRQYLTYSLSAAAAAILLLVGISGIY
                     RHLSPAPANYVIIDGKEYTDVHLIREQAMVAFRDVSLSEEEVFATLFDE"
     CDS             7951..8400
                     /locus_tag="ctg140_11"
                     /transl_table=11
                     /translation="MMNKIIRTTLITLLLTFAAHAAAQQGLQIATVFQKYGKQKGVTMV
                     ELSNEMLETYQMTLYKSLVFKDASDALPTILRCLEADKKKAKKVKEVVSNGQIKSGYYQ
                     LPQLKEDVNRFILFKTGKKDSATLIYIEGELDADDLITMLFMKKE"
     CDS             8425..9327
                     /locus_tag="ctg140_12"
                     /transl_table=11
                     /translation="MKKLLLLWLMIAPMSGMAQNESTPQDTTLYVNGRKIVIKEQGDKI
                     KVKLYESASGGDTITNAQIFEGVYLNGQSTESRTVLSALPFSKKNNKRNRFEPHAGGFY
                     IGYTRLSNDFLSFNPSNGADLNTSHSWEIGGNLFTGSHAFAPTYNWGITIGLGWGYRSM
                     RLDGNYAFREIDGVTEIYSGMEAEEPTEYSKSRLRYFYFRIPLSIEWQTRLNGKGPLFF
                     AVGPEAEIRHGFRSKAKVNGSKKTIDKGLNGRPLGINLLAQAGYADLGVYMRYSTYGLF
                     EKNKGPELYPFSFGVCWYW"
     CDS             9441..10427
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GFO_IDH_MocA"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GFO_IDH_MocA_C"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg140_13"
                     /sec_met_domain="GFO_IDH_MocA (E-value: 7.2e-28, bitscore:
                     88.1, seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="GFO_IDH_MocA_C (E-value: 7e-10, bitscore:
                     29.2, seeds: 24, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSEKMIKWGFIGCGEVTKTKSGPAFQKVEHSEVVAVMSRDGAKAK
                     AYAKERGIRKWYDDAQELIDDPEVNAIYIATPPSSHATYAIMAMKAGKPAYIEKPMAVT
                     YEECTRINRISKETGVPCFVAYYRRYLPYFQKVKEMVENGSIGNVINVQVRFAQPPRDL
                     DYNRENLPWRVQADIAGGGYFYDLAPHQIDLLQDMFGCILEASGYKSNRGGLYPAEDTL
                     SACFQFDNGLVGSGSWCFVAHDSAREDRIEIIGDKGMICFSVFTYEPIGLHTERGREEI
                     CIGNPEHVQQPLIQAVVDHLLGKSVCSCDGESATLTNWVMDKILGKL"
     CDS             10567..11019
                     /locus_tag="ctg140_14"
                     /transl_table=11
                     /translation="MRKAIELSKENVANGGGPFGAVIATKEGEIIATGVNRVTSSCDPT
                     AHAEVSAIRAAAAKLGTFNLSGYEIYTSCEPCPMCLGAIYWARLDKMYYGNNKTDAKNI
                     GFDDSFIYDELALKPADRKLPSEVLLHNEAITAFEAWMSKEDKVEY"
     CDS             11057..11860
                     /locus_tag="ctg140_15"
                     /transl_table=11
                     /translation="MKRKNFLILLAAGCLFSCQQQDELQETSKEATNFSISIDDALSDP
                     LTRTSNDLFPARNSITTGEVISMAASGQDYTPFIVGKDSRAWNEIGTATGTVTFYAHYP
                     ALTDEAATRSGGNKRYLKGGQEHLFGTAEAAPGSQNVSLKFKRMTVPVIILDENDRPYE
                     GEAKVELSLKNEGTQDLLNGTIEINENALSENIEVKKVSEGVTTNVLPQKINAGEEIGT
                     ITVGGVTQKISAVEDLDLKAGSTLSVRLSKKFGGGIIDGNVPLYR"
ORIGIN
        1 acagcaactg tatacgttct tttatttcca tattattctt tgattctgca cataaataaa
       61 gatgttattc accttaccgc ctatgcattg tttgcagata aacggcttgc aaatatacgg
      121 ttttacctgt cattaacata aatacatctt ctctaattct gtcttttata ctcaagaatt
      181 atcttaaggc atatttaata ttgattattt attcacccaa tatgcaataa aaacaaaagg
      241 aggtaaattt cctttctcat tttcccccat ttacataaat aaaaactatc tttgcgattc
      301 agaatcccga aagacgaaag aaaatggagc aaatagacaa cctaaaagag cttatcaatc
      361 aaggggatgt ggacatagca atcaagcaat tggaccaact tctccaagac gattctgtcg
      421 agaaagataa agatatgctc tactatttac ggggaaatgc ctaccgaaaa aaaggagatt
      481 ggaagcaggc gctgaataac taccagtatg ctatcgatct taatcccgac agccccgctg
      541 ttcaagccag aacaatggcg atagatatcc tgaatttcta ccacaaagat atgtataatc
      601 aataaccgaa ttcaaagata acgtaataaa atagagatta tggcaaaaat taaaggagca
      661 atcgtagtcg acacggagcg ttgcaaagga tgcaacctat gtgtagtagc gtgtccgctc
      721 gatgtaatcg ccctcaacaa agaggtgaat atgaaaggct ataactatgc ctggcaagta
      781 aaagaagata cctgcaacgg atgcagctcg tgtgcaatgg tttgtcccga cggatgtatc
      841 tcagtgtata aagtaaaagt agaataaaag aaaaagaata tggcagaaga agttgtatta
      901 atgaaaggaa acgaagccat cgcccacgca gctatccgtt gcggtgcgga cggatacttc
      961 ggatatccta ttactcccca atcggaagta ctggaaacgc ttgccgaact gaaaccgtgg
     1021 gaaacaaccg gcatggtagt tctccaggca gaaagtgaag tggcagctat caatatggta
     1081 tatggaggcg caggtagtgg aaagatggta ttgacctctt cctcaagtcc cggcgtgagt
     1141 ctgaaacagg aaggtatctc ctacatcgca ggtgccgaac ttccttgtct gattgtaaac
     1201 gtaatgcgcg gcggccccgg attgggaacc atccagccga gtcaggcgga ctacttccag
     1261 acagtgaaag gaggcggtca cggtgactac aggctgattg ccctcgctcc ggcatccgta
     1321 caggaaatgg cggatttcgt ggcactggga ttcgagcttg ctttcaaata ccgtaacccg
     1381 gctatcatcc ttgccgacgg tgtaatcgga cagatgatgg aaaaagtagt tcttcctgca
     1441 cagaagccac gccgcaccga tgcagaagtt atcgaacaat gtccgtgggc tgctaccgga
     1501 aaagcgaaag gtcgtaaacc gaatattatt acttcactcg aactgaagcc ggaagcaatg
     1561 gaaatcaaca acatccgttt ccaggctaaa tacaaacaga ttgaggaaaa cgaagtacgc
     1621 ttcgaagaaa tcaactgcga agatgcagaa tatctgatca tagctttcgg ttccatggca
     1681 cgtatcggtc agaaagcaat ggaactcgcc cgcgaaaaag gaatcaaagt aggtattctt
     1741 cgccccatca ctttgtggcc gttcccgagc aaagccattg ccgcttacgc tgacaaagtg
     1801 aaaggtatgc tcgttacaga attgaatgcc ggacagatga tcgaagatgt ccgcctggct
     1861 gtcaatggta aagtaaaagt agaacatttc ggacgtctcg gcggtattgt tcccgatccg
     1921 gatgaaattg taactgctct ggaagaaaaa ataatcaaat aacgaaacga cgatgaatcc
     1981 cgataaaata agaaacgtat tgaacatcct tttcatgata ttggcacttg ccgctatcat
     2041 tgtctacttt gtagtaggaa aggaagattt taaaatgttt atctacgtat gcggcgcggc
     2101 aatctttgtc aagctgatgg agttttttat acggttcacc aacagataag gagaagaagt
     2161 tatgactaaa gaagaaataa tcaaacctga gaatctggtt tataaaaaac cgactctgat
     2221 gaatgataat gccatgcact actgcccggg ttgcagtcac ggcgtggtac acaagctcgt
     2281 tgccgaagtc attgaggaaa tgggcatgga agaaaaaacg gtgggagtct ctccggtagg
     2341 atgcgcagtt ttcgcctaca actatctgga tatagactgg caggaagccg ctcacggacg
     2401 tgcacctgca gtagctacgg ctatcaaacg cttatggccc gaccgtctcg ttttcactta
     2461 tcagggtgac ggtgacctgg cctgtatcgg taccgccgaa acaatccacg cactgaaccg
     2521 tggcgaaaac attactatta tctttatcaa taacgctatc tacggtatga ccggcggaca
     2581 aatggctccg acgactctgg taggcatgaa gagttctact tgtccttacg gacgtgatgt
     2641 cgaactacac ggctatccat tgaagataac cgagattgcc gcccaactgg aaggaactgc
     2701 ttacgttacc cgtcagtcgg tacaatcagt gcccgccatc cgcaaagcca agaaagcaat
     2761 acgcaaggca ttcgaaaatt cgatgaacgg caaaggttcc aatctggtag aaatcgtatc
     2821 aacttgtagc tccggctgga agatgactcc ggaaaaatca aataaatgga tggaagaaca
     2881 tatgttccca ttctatccac tgggtgattt aaaagataaa gaataacgca aaagtcaaca
     2941 gaacaatgaa agaagaaata attattgctg gattcggcgg acaaggcgta ttgtccatgg
     3001 gtaagattct ggcttattcc ggactgatgg aaggaaaaga agtgagctgg atgccggcat
     3061 acggtcctga acaacgaggc ggaacagcca atgtgacagt gattgtcagc gatgacaaaa
     3121 tctcttcacc gatcctgagt aaatatgata cggcgatcat actgaaccag ccttcactgg
     3181 aaaagtttga aagcagagta aagccgggcg gtatcctgat ctatgacgga tatgggatta
     3241 tcaaccctcc tacccgcaag gatatcaaag tatatcgcat cgacgcaatg gatgctgcca
     3301 acgaaatgaa taatgcgaaa gccttcaata tgatcgtact tggcggttta ctgcaactcc
     3361 gtcctatcgt aactctggaa aacgtcatca aaggattgaa gaaaactctt ccggaacgcc
     3421 atcaccactt gattcctatg aacgaggaag cgatcaaaaa aggaatggaa ttaatccacg
     3481 aagtttaata aattaagagt ttaaaattga gaattgagaa ttatttgcta gataatagcg
     3541 cgatgcaaca taattttcaa ttctcaattc tcaattctca atttaagtaa gtatctttgc
     3601 ctccaattat gagacgaatc ttactattat atatattatt ctccgttgta ggactgagtg
     3661 ctatccatgc acagctcaac cctgcccgcc agcaaatcga cgagaacgga cgcgaccaat
     3721 atggtaatca ggtagaccct gccatgattc cggacaaact ggatagtgcc aatgttgaag
     3781 tacagggact gccgcctaca ctatatatgt ggcgtatcaa gaaccaatta ggcgaccgga
     3841 caatgattcc ggcagataca acttaccatc actttcagaa tacgaatctt acagaaggaa
     3901 tcaccggaca ttataattat ctggccaatt taggttcacc gcgtctgtcg cgtatcttct
     3961 ttgagcgccg ttatccggaa ccaaccatct ttatggagtc tttctccagc tttttcattc
     4021 gcccgacgga atttaacttt acgaatagta atgttcctta tactaacctg acctatcaca
     4081 aggccggaaa taagcaaaat ggagaagaac gtttcaaatc ttatttttca gtcaatgtaa
     4141 acaagaagtt ggctttcggc tttaatattg attatctgta tggccgaggc tactataata
     4201 atcaaaacac ttcttatttt aatgccgcgc ttttcggtag ttacattggc gaccgctatc
     4261 aggtgcaggg aatctatagc aacaactatc tgaaaacgaa tgagaacggt ggtatcactg
     4321 acgaccgcta cattaccgca ccggaagaaa tggcagaagg aagaaaagaa tatgaatctg
     4381 tcaatatccc taccgtactc aatgccagtg ccaaccgtaa ccatgacttc tatgtctttc
     4441 tgacacaacg ctataatctg ggattccacc gggatattcc acaggcagaa aatgatacga
     4501 tgcctgccaa acaggaattt gttccggtca ccagctttat acataccatt caggtagaac
     4561 gttcgcgcca taatttccgt tcggatgata atgtagaaaa ctattataag caaactctcc
     4621 ttgataaaga gaatacattc gtcagagaca gtactgtcta tatcggagtc aagaatacca
     4681 taggtattgc tttgctcgaa ggcttcaaca aatatgcaaa agccggattg acagcctttg
     4741 cctcacataa gctgagcaaa tattcattaa tgagcctaga cccgctaaag caggataaat
     4801 acaatgagac agaaatctat atcggtggcg aactgactaa aaaacaggga aactttcttc
     4861 attatcatgc aatcggtgaa gtgggaatgg caggaaaggc tatcggacag tttgatgtca
     4921 aaggagatat cgacttaaat atccctttat ggaaagatac cgtcagtgtg attgcacgcg
     4981 gagaaatcag taataaactt gctccattct acatgcgtca ttaccactcc aaacattttt
     5041 ggtgggatga tgatatggat aaggaattcc gcacccgtat cgaaggcgag ctgagcatag
     5101 ctaattgggg gacccgctta agagccggtg ttgaaaatat aaagaactat acttatttca
     5161 accagcaggc attaccggaa caaaaaggtg gtagtttgca agtagtatca gcttgcttca
     5221 atcaggattt caaagtggga atcttccatc tggacaatga agtgatctgg cagaaatcca
     5281 gtgatcaggc tgtacttcca ttgccggaac tttcgctgta tcataacttc tatatgcagt
     5341 tcaaactggc gaaaaaagta ttgagtgtac aattaggtgc tgatgtacgt tacttcacta
     5401 aatatgatgc tccggcctat atgcctgcta cacagcagtt ctacctgcaa ccggaagaag
     5461 gtaaagtaga gataggcggt tatccgatag tgaatgttta tgctaactta cacttgaaac
     5521 gtacccgttt ctatgtgatg atgtatcacg tcaatcaggg aatgagcaaa cctaattact
     5581 tcctagcacc tcattacccc attaacccac gtgtgctgaa attcggactt tcatggaact
     5641 tctatgatta acaaaacctc tatggcttat gaaaacgcgc ccgaaattga gactattcag
     5701 atatctgttg ccggtagtca ttgtattggc acttatcttc tctgtccgct attgcggtaa
     5761 acaagaaaaa cctctggggc atccgcgtga ttacgcagcc atcgccaaag aaggcatcct
     5821 gcatgtagcc accgaatata attcaatcag tttttatgta gacagtgaca ctgtctccgg
     5881 attccattat gaactgatag aagcgttcgc acgtgacaag gggctgaaaa ctgaaatcac
     5941 tcctgtcatg agcttcgacg aacggctgag aggattaagc gacggacgct acgatgtcat
     6001 agcatacgga atactggcaa ccagcgaact gaaagattct ctgcttctca cctcccccat
     6061 catactcaac aagcaggtgc tggtgcaacg aaaagcgaac ggggagaatg attcacttta
     6121 tatccgaaac caattggacc ttgcccaaaa gacacttcat gtggtaaaag gctcgccttc
     6181 tattctacgt attcagaatc tgggaaatga aatcggagat actatttata taaaggaaat
     6241 agagaaatac ggttcagagc agttgatttc gttagttgct catggagata tcgattatgc
     6301 cgtctgtgat gaaagcattg cccgtgcagt ggtagattca ttgcctcagg tagatatcaa
     6361 taccgcaatc agttttactc aattctactc atgggcagtc agcaagcaat cacccgcatt
     6421 gctcgatagt ttgaatacat ggctggataa attccaaaaa gaaaaagagt atcaaaagat
     6481 ttaccggaaa tactatggtg ataaatagat aaaaaataat acgccgaaga cttgactttc
     6541 gcatttgaat gtcgtatctt tgtcaacgta atcataaagt agtttcagtt aaactacacg
     6601 taaaggaggg aatcacagtt ccctcctttc tttttgttac aatgaatgaa aatcagcctt
     6661 tttcccagct ttttgctcat tttacccccg agcttagtcc gttttacctc gtttgttacc
     6721 atacttaaca tagtatctta tgactaatta gatgctttgt tatgattaat cagatgcttt
     6781 gttatccata aaccgatgct ttgttctccc aaaacagaag ctctgtttcc ggacagctcc
     6841 caagagttaa caatcaataa agttgctctt gacaaaaatt tgctctactt ttgaaaaaaa
     6901 ttcccttttc gatgtcacgt ttttaatccg ccaccgtctt atcagtgtaa atggaactga
     6961 aacaatttaa aataaccgtt gtaccccttc gagacaagct gctgaactac gcccgaagga
     7021 tgacagatga tccttcggat gcggaagatg ccgtacagga agtcatgctg aagctgtgga
     7081 atctgcgcca gaagctagac gagtacagaa gtatcgaagc cgtagccatg accatgacgc
     7141 atcatctctg catggatatg tggcgtgcca aacgaccgga cactctatca ctcgaccgtg
     7201 tacaggctcc caccccttcg gctactccgg agcgactgct ggaagagaaa gatgagttca
     7261 gattgatgcg ggaaattatc gactccctgc ctacgctgca acgaacgatt attcgcatga
     7321 aagacatcga agagtacgag acggaagaga ttgccgaaat caccggctgc aacgcagaag
     7381 ccatccgcag taatctgtcg agggcccgca agaaagtaag ggaagtctat ttgcaaacga
     7441 tacaagaacg aaaaaggagg aacaaagcat gaaagatata gaaaccttgc taaacaaata
     7501 tttcgaagga gaaaccactt gcgaagaaga acgcagacta cgacgtttct ttgccgaagg
     7561 gctcgtaccg gaacatctgg aggtatatcg cccgatgttc gctttcttcg aagcggaaca
     7621 gaaggaactt gcggaaatct ccggtaaagg taatgccgcc gagatgccgg aactcgcccc
     7681 attcgagaaa aagacaaaaa cggtcagaca gtatctgact tacagtctca gtgctgccgc
     7741 tgccgccatc ctgctactgg tgggcatctc cggtatctac cgtcatctat cccctgcacc
     7801 ggccaactat gtgatcattg acggtaagga atatacggac gttcatttaa tccgtgaaca
     7861 ggcgatggtc gcctttcgtg acgtcagcct cagcgaggag gaagtattcg ctactttatt
     7921 tgatgaataa tataaaaaca gcatataatt atgatgaata aaatcattcg taccacacta
     7981 atcaccctgt tacttacatt cgccgcccat gcggccgccc aacagggact acagattgcc
     8041 accgtcttcc agaagtacgg aaagcaaaaa ggggtaacta tggtagagct atccaatgaa
     8101 atgctggaaa cttaccagat gactctttat aaaagtcttg ttttcaagga tgccagcgat
     8161 gcactaccta cgattctccg ttgcctggaa gccgacaaga agaaagcaaa gaaggtgaaa
     8221 gaagtggttt ccaacgggca aatcaagtcc ggctattacc aacttcccca gcttaaggaa
     8281 gatgtgaacc gctttatcct cttcaaaacc ggaaagaaag attcggctac ccttatctat
     8341 attgaaggag aactggatgc cgacgacctg atcaccatgt tattcatgaa gaaagaataa
     8401 aaaaacagat aaagaaatac gaatatgaaa aaactattat tactatggct catgatagct
     8461 ccaatgagcg gcatggcaca aaatgaaagt acaccgcagg atacaacact ttacgtcaac
     8521 ggacggaaga tcgtaatcaa ggaacaaggc gacaagatta aagtgaaact ctacgaaagc
     8581 gcatccggcg gagatacgat aacaaacgcg caaatcttcg aaggagtcta cctgaacggg
     8641 cagagtacgg aaagccgtac cgtgctgagc gctctcccct tctcgaagaa aaacaacaag
     8701 agaaacaggt tcgagccaca tgccggcgga ttctacatcg gctacacccg actgtccaat
     8761 gacttcctct cattcaatcc gtcgaacggt gccgacctca acaccagtca ttcatgggag
     8821 ataggcggca atctgtttac cggttcgcac gcctttgcac ctacctataa ctgggggatc
     8881 accatcggac taggatgggg ataccgcagt atgcgcctgg acggcaatta tgcttttcgt
     8941 gaaatagacg gagtgactga aatttactcc ggcatggagg cagaagagcc tacagagtac
     9001 agcaaaagcc gtctgcgcta tttctacttc cgcattccgc tctctatcga atggcaaaca
     9061 cggctcaacg gcaaaggtcc tttgtttttt gctgtaggtc ccgaagccga aatacgtcac
     9121 ggattcagat ccaaagccaa agtcaatgga tcgaagaaga cgattgacaa gggactgaac
     9181 gggcgcccgc taggtatcaa cttacttgca caagccggtt atgcagattt aggagtgtat
     9241 atgcgttact ccacctacgg cctctttgag aagaacaaag gtcccgaact ttatccgttc
     9301 tctttcggtg tatgctggta ctggtaaagt aaatactcag acccttgcct atttctgaca
     9361 gttaacaatc aataaagttg ttcttaataa aaaatagctt tatctttggg agttgttaaa
     9421 acaagcacaa taggtatatt atgagtgaaa agatgattaa atggggcttc atcggctgcg
     9481 gagaagtaac caaaaccaaa agtggccccg cctttcaaaa ggtagaacat tctgaagtag
     9541 tagctgtaat gagccgcgac ggcgccaaag caaaggctta tgcaaaagaa agagggatca
     9601 gaaaatggta tgatgacgct caggaactga tagacgatcc ggaagtaaat gccatttata
     9661 tcgccactcc tccttcttca cacgctacat acgccattat ggctatgaaa gcaggcaagc
     9721 ctgcctatat tgaaaaacca atggctgtca cttatgagga gtgtacacgt atcaaccgta
     9781 tttctaagga aacgggtgtt ccctgtttcg tcgcatatta ccgccgctat ctcccctact
     9841 ttcagaaagt gaaagaaatg gtagagaacg ggtctatcgg taatgtcatc aacgtacaag
     9901 tccgctttgc acagccgcca cgtgatttgg attacaaccg tgaaaatctt ccttggcgtg
     9961 tacaggctga tattgccggt ggcggttact tctatgacct tgccccgcat cagatcgact
    10021 tgctgcaaga tatgttcggc tgcatcctcg aagccagcgg atataagagc aatcgtggag
    10081 ggctttatcc tgccgaagat acgctgagcg cctgcttcca gttcgacaac ggattggtcg
    10141 gcagtggttc atggtgcttt gttgcccatg attccgcccg tgaagaccgc atcgaaatta
    10201 tcggagataa aggtatgatc tgcttctctg tctttacgta cgagccgatt ggtctgcaca
    10261 ccgaacgcgg ccgggaggaa atctgtatcg gtaaccctga gcatgttcaa caacctctta
    10321 ttcaggcagt agtagatcat ctgctcggta agtcagtctg ctcatgcgac ggagaaagtg
    10381 ctaccttgac taactgggta atggacaaaa tattagggaa gctctaagat aaagctcctt
    10441 cgtttgtttc ttaaaataat ttaatcacta tattctatcg ttagttttct ttatatttgc
    10501 gaaaggtagc aataaaagca aaactaacga tatttatttt ttataactat gaccaaagaa
    10561 gaactaatga ggaaagcaat agagctttcg aaggaaaatg ttgctaatgg tggaggcccg
    10621 ttcggagctg tcattgcaac aaaagaagga gaaattatag ctacaggagt caacagagta
    10681 acctcttcat gtgatcccac tgctcatgcc gaagttagcg ccatacgtgc cgcagccgcg
    10741 aaactgggaa cattcaacct cagcggatac gaaatctata cttcatgcga accttgcccg
    10801 atgtgtctgg gtgccatcta ttgggcacga ctggacaaaa tgtattatgg gaacaacaaa
    10861 acagatgcca aaaacatcgg tttcgacgat tcctttattt atgatgagct ggctctaaaa
    10921 cctgccgaca gaaaacttcc ctcggaagta ttattgcaca acgaagccat tacagccttc
    10981 gaagcctgga tgtccaaaga agacaaagta gaatattagc atctaatctc acttaaactc
    11041 actaatactt agtaaaatga aaagaaaaaa ctttttgatt cttctagccg caggatgttt
    11101 gttcagttgt cagcaacagg atgaactgca agaaacaagt aaagaagcaa ccaacttctc
    11161 tatctctatc gacgacgctc tctctgaccc gctcacccgt accagcaatg atctgttccc
    11221 tgccagaaat agcatcacta caggagaagt tatctccatg gctgcctccg gtcaggacta
    11281 tactccgttt attgttggca aagacagccg cgcatggaac gaaataggaa ctgccacagg
    11341 cacagtaacc ttctacgccc actatcctgc attgacagac gaagccgcta ccagatcagg
    11401 cggtaacaaa cgctatttaa aaggaggtca ggagcacttg ttcggaacag cggaagcagc
    11461 tccgggcagc cagaatgtat cactgaaatt caaacgaatg accgtgccgg ttattatact
    11521 tgatgagaac gatcgtccgt atgaaggcga agctaaagtt gagctcagcc tgaaaaacga
    11581 aggtacgcag gatttattga acggtaccat agaaatcaac gaaaatgcgc tgtcagagaa
    11641 tatcgaagta aagaaagtat ccgaaggcgt tactaccaat gttctcccgc aaaagatcaa
    11701 tgctggagag gaaataggaa cgatcactgt cggaggagtc actcagaaga tcagtgcagt
    11761 ggaagatctt gatttaaaag ccggaagcac actttctgtc agattatcaa aaaaattcgg
    11821 aggcggtatt attgatggta atgttccatt gtacagataa gaagattgca cttaaagaca
    11881 atcttgcaga ttatataaat ataaagaacg ggattcgtat gaatcccgtt cttttattta
    11941 gacctaaaaa ctatataata agccggtcag tccccaagag ccgaccgact tatttataac
    12001 actttattac ttatcccacc atacgcgtga tgtcatctta tcgcctccgc taagtctctt
    12061 aacggcatca ttgtaattaa caggattagc tgttatttca cttgtcggat aaatgaaacg
    12121 acgaggaatc tctccatttg tcacattgtt aggatagctg gctgcatttc gagccggggt
    12181 taattttgga tatccggtac gacgccaatt tgcaaaagct tcatactcat tacagaacgt
    12241 atggatataa tattccgtat taatctgttc cagcgctttt tccgtatcag catccaatgg
    12301 attagcattc agataggcag ttatcgcatc atctgtaatc gtagctgagg ctttttcata
    12361 ataggagaat tgtttcatgg cagcagttac tccatctcta taaaattttt ctgcatctcc
    12421 tgtatagagt ccacgtttca ctgcatcagc caataataac aagttaccgg catgagtgac
    12481 aagcatagag ggtgaatccg ggcgtgcata aactgtacgg ttaggaacag aatatgcttt
    12541 tctccaatca acctgatagc ttggagcttt actcaaatcc cagtctcctc ctgacacatc
    12601 ataaccaacc ggcatacctt tctgcttagc agccgtgttg tcacctaaat caaaatcagc
    12661 atctccccat cccggtttag gatctctggt acaaactgta gcaatcagag gaagacgagg
    12721 atcgtcctga aggatgttta taaatgtttc gctgatatag aacgcctgag tatccagact
    12781 ggaaaatact tttccgtaag gttctgcaga gtcatcgctt ggcgaaccat tggtatgtct
    12841 gacgatcgca ttatcatcgt tgcttacgaa cagcccattt gaaactgctt tagctaccca
    12901 tgttttcgct ttatcaggag caactttggt caaccgcatg gctacccgga gcatcagtga
    12961 attagcaaat ttcttccatt tcgcagcatc accgccatag ataacgtcag cagctcctat
    13021 cgtattaccg gcagaagtgc ttaatgcagc ttgtgcttca tctagttctt tcagcagatc
    13081 atcatagatt gcttcttgtg tatcatattt aggatacgga atcggattgg tagaataccc
    13141 ctgccctgct tcagaataag gaacgtctcc ataaaggtca gtcatattct ggaacatata
    13201 tgctttcaga atgcggcaca tctgatattc attcgtataa gcgggatctc cttcccaatt
    13261 attcatcaca tctataatat tgcgaatagc tgcacgccca ccagaataga atcctcccca
    13321 ataagcacca ctatactgat cgttccatgt atagaaaact ccatacgccc aatctacgct
    13381 agccgtatgc tgtatcatgt tggctgtgta aatacagcca ttacgccaca cgtcccagtc
    13441 ggagccacat atctgtgctt caacctgagt aaattccatt ttataatc
//
