LOCUS       c00219_gnlPro..         8566 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|AEKFAAGK_219.
ACCESSION   c00219_gnlPro..
VERSION     c00219_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-05 12:13:44
            Original ID  :: gnl|Prokka|AEKFAAGK_219
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 8566
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..8566
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[2791:7648]"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and (minimum(2, [ACD1_car,
                     ACP_syn_III_C, AcetylCoA_hyd_C, AcetylCoA_hydro,
                     Acyl-CoA_dh_1, Acyl-CoA_dh_2, Butyrate_kinase,
                     CT_Propionyl_CoA1, CT_Propionyl_CoA2, CT_Propionyl_CoA3,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_2_CAF, CoA_trans_6_Glutaconate, E1_dh, ECH_1,
                     ECH_2, HBT, HBT_2, HCDH, HpaB, Ketoacyl-synt_C, Thiolase_C,
                     Thiolase_N, adh_short, adh_short_C2]) or FA_synthesis) and
                     not (PFL-like or PFL_6_pcresol or PFL_9_tma or Gly_radical
                     or Gly_430_pcre or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and not
                     (POR or POR_N))"
                     /neighbourhood="10000"
                     /product="TPP_fatty_acids"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      2792..7648
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and (minimum(2, [ACD1_car,
                     ACP_syn_III_C, AcetylCoA_hyd_C, AcetylCoA_hydro,
                     Acyl-CoA_dh_1, Acyl-CoA_dh_2, Butyrate_kinase,
                     CT_Propionyl_CoA1, CT_Propionyl_CoA2, CT_Propionyl_CoA3,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_2_CAF, CoA_trans_6_Glutaconate, E1_dh, ECH_1,
                     ECH_2, HBT, HBT_2, HCDH, HpaB, Ketoacyl-synt_C, Thiolase_C,
                     Thiolase_N, adh_short, adh_short_C2]) or FA_synthesis) and
                     not (PFL-like or PFL_6_pcresol or PFL_9_tma or Gly_radical
                     or Gly_430_pcre or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and not
                     (POR or POR_N))"
                     /neighbourhood="10000"
                     /product="TPP_fatty_acids"
                     /protocluster_number="1"
     cand_cluster    1..8566
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TPP_enzyme_C and (minimum(2, [ACD1_car,
                     ACP_syn_III_C, AcetylCoA_hyd_C, AcetylCoA_hydro,
                     Acyl-CoA_dh_1, Acyl-CoA_dh_2, Butyrate_kinase,
                     CT_Propionyl_CoA1, CT_Propionyl_CoA2, CT_Propionyl_CoA3,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_2_CAF, CoA_trans_6_Glutaconate, E1_dh, ECH_1,
                     ECH_2, HBT, HBT_2, HCDH, HpaB, Ketoacyl-synt_C, Thiolase_C,
                     Thiolase_N, adh_short, adh_short_C2]) or FA_synthesis) and
                     not (PFL-like or PFL_6_pcresol or PFL_9_tma or Gly_radical
                     or Gly_430_pcre or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and not
                     (POR or POR_N))"
                     /kind="single"
                     /product="TPP_fatty_acids"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..8566
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="TPP_fatty_acids"
                     /region_number="1"
                     /rules="(TPP_enzyme_C and (minimum(2, [ACD1_car,
                     ACP_syn_III_C, AcetylCoA_hyd_C, AcetylCoA_hydro,
                     Acyl-CoA_dh_1, Acyl-CoA_dh_2, Butyrate_kinase,
                     CT_Propionyl_CoA1, CT_Propionyl_CoA2, CT_Propionyl_CoA3,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_2_CAF, CoA_trans_6_Glutaconate, E1_dh, ECH_1,
                     ECH_2, HBT, HBT_2, HCDH, HpaB, Ketoacyl-synt_C, Thiolase_C,
                     Thiolase_N, adh_short, adh_short_C2]) or FA_synthesis) and
                     not (PFL-like or PFL_6_pcresol or PFL_9_tma or Gly_radical
                     or Gly_430_pcre or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and not
                     (POR or POR_N))"
                     /tool="gutsmash"
     CDS             117..686
                     /locus_tag="ctg219_1"
                     /transl_table=11
                     /translation="MKISFSRQTKERAFKQLYEDYYAPFCLYAKRFVDDKEVREDIVSD
                     VFTSLWDKLDTDSFDLQSETALGYIKMCVKNSCLNFLKHQEYEWSYAENIQKKAPLYET
                     ETDSVYTLDELYRMLYETLNKLPENYRTVFMKSFFEGKTHAEIAEEMNLSVKSINRYKQ
                     KTMELLRNELKDYLPLFLLFLSPEQL"
     CDS             complement(660..1766)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1025:AMP-binding enzyme (Score: 52.9; E-value:
                     7.6e-17)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg219_2"
                     /sec_met_domain="AMP-binding (E-value: 1.1e-17, bitscore:
                     52.9, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MMIFDRQKQRLLLEGKEYTPGDIHSLVAEGEGNHPSAIWDLYLFL
                     NEWFNDDPVITVHTSGSTGAPKELLVRKDQMIQSARLTCEFLDLKQGETALLCMNLRYI
                     GAMMVVVRSLIAGLNLIVRRASGHPLADVDTPLRFAAMVPLQVYNTFQIPEEKEKLKQT
                     EILIIGGGAVDKALEEKIRNLSNAVYSTYGMTETLSHIALRRLNGAAASDRYYPFSSVE
                     LFLSSENTLMINAPLVCDDTLQTNDIARIYPDGSFTILGRKDNVINSGGIKVQAEEIER
                     LLQSSIPVPFVITSVPDRRLGQAVTLLIEGQMEISALGTKLESVLASYYRPKYIYTVNH
                     IPQTGNGKINRKECRVLAESLQLLGRQE"
     CDS             complement(1763..2788)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) MR_MLE_C"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg219_3"
                     /sec_met_domain="MR_MLE_C (E-value: 3.3e-30, bitscore:
                     94.5, seeds: 401, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDCKIDIIPRVLHFKQPAGTSRGTYTTRKVWYLHFTAPEFPNWVG
                     IGECAPLPNLSCDDLPDYEEVLAKICRQVENQGGKLDMEALCKYPSILFGLETAIRHFF
                     EGSWALWDTPFSRGEAGIPINGLIWMGDFNRMLAQIEKKMEAGFRCIKLKIGAINFEEE
                     LALLQHIRSHYSSKEIELRVDANGAFSPTDAMEKLKRLSELDLHSIEQPIRAGQWEEMA
                     RLTSESPLPIALDEELIGYNTWEEKQRLLSAIRPQYIIIKPSLHGGLAGGEEWIAEAEK
                     LNIGWWITSALESNIGLNAIAQWCATFQNPLPQGLGTGLLFTDNVEMPLEIRKDCLWFC
                     K"
     CDS             complement(2792..3616)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_fatty_acids: ECH_1"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg219_4"
                     /sec_met_domain="ECH_1 (E-value: 7.2e-81, bitscore: 260.4,
                     seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSTQREWTTIREYEDILFDYYNGIARITINRERYRNAFTPTTTAE
                     MSDALRICREEADIDVIVITGAGDKAFCSCGDQNVKGRGGYIGKDGVPRLSVLDVQKQI
                     RSIPKPVIAAVNGFAIGGGHVLHVVCDLSIASENAIFGQTGPRVGSFDAGFGASYLARV
                     VGQKKAREIWFLCRKYNAQEALDMGLVNKVVPLEQLEDEYVQWAEEMMLLSPLALRMIK
                     AGLNAELDGQAGIQELAGDATLLYYLTDEAQEGKNAFLEKRKPNFKKYPKFP"
     CDS             complement(3620..5287)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_fatty_acids: TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg219_5"
                     /sec_met_domain="TPP_enzyme_C (E-value: 4.4e-09, bitscore:
                     25.6, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MYSDKKNILQLVALLEAHGITKVVLCPGSRNAPIVHTLSTHPGFT
                     CYAMTDERSAGYFAIGLALNGGHPAAVCCTSGTALLNLHPAVAEAYYQNIPLVVISADR
                     PAAWIGQMAGQTLPQPGVFQTLVKKSVNLPEIQTEEDEWYCNRLVNEALLETNHHGKGP
                     VHINIPISEPLFQFTVESLPEVRVITRYQGLNVYDRDYNDLIERLNRYQKRMIIVGQMN
                     LIYLFEKRHTKLLYKHFVWLTEHIGNQTVPGIPVKNFDAALYAMPEEKTGQMTPELLIT
                     YGGHVVSKRLKKYLRQHPPKEHWHVSADGEVVDLYGSLTTVIEMDPFEFLEKIAPLLDN
                     RVPEYPRVWENYCKTIPEPEFGYSEMSAIGALIKALPESCALHLANSSVIRYAQLYQVP
                     STIEVCCNRGTSGIEGSLSTAVGYAAGSDKLNFIVIGDLSFFYDMNALWNINVRPNLRI
                     LLLNNGGGEIFHTLPGLDMSGTSHKYITAVHKTSAKGWAEERGFLYQRVENEEQLAEAM
                     KTFTQPEAMEQPVLMEVFSNKNKDARILKDYYHQLKQK"
     CDS             complement(5307..6419)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Chorismate_bind"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg219_6"
                     /sec_met_domain="Chorismate_bind (E-value: 2.4e-58,
                     bitscore: 186.9, seeds: 119, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIDEKSNLTTIDALIQRKQPFAVYRVPGEKYPRLLTEDVGAVRLI
                     FDLKELNGQRGFVIAPFRIDKSCPIVLIQSDRTGQPLPMEIVAEEEQDLQSYPEESFHT
                     LCTGKYATCFHTFIEALRDATFDKLVLSRSLTIGKNPEFSPSAVFRAACQRYIHSYIYL
                     CYTPQTGVWLGSTPEIILSGEKNEWNTVALAGTQPLQNGKLPQVWDDKNRQEQDYVASY
                     IRRQLLSLGIRSTESGPYPAYAGALSHLKTDFHFSLKDNKNLGDLLKVLHPTPAVCGLP
                     KEEAYRFILENEGYDRKYYSGFIGWLDPEGRTDLYVNLRCMHIEDEQLTLYAGGGLLAS
                     SELNDEWQETEKKLQTMRRILVSAPIMMNH"
     CDS             complement(6416..7648)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_fatty_acids: HBT"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg219_7"
                     /sec_met_domain="HBT (E-value: 1.6e-17, bitscore: 53.0,
                     seeds: 132, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKYKLLVLDVDGTLLNDAKEISKRTLAALLKVQQMGVRIVLASGR
                     PTYGLMPLAKSLELGNYGGYILSYNGCQIINAQNGEILFERRINPEMLPYLEKKARKNN
                     FALFTYHDDTIITDTPENEHIQNEARLNNLKVIKEEEFSVAIDFAPCKCMLVSDDEEAL
                     VSLEGHWKRRLNGALDVFRSEPYFLEVVPCAIDKANTLGALLEELDVKREEVIAIGDGV
                     CDVTMIQLAGLGVAMGHSQDSVKVCADYVTASNEEDGVALAVEKAIIAEVRAAEIPLDQ
                     LNAQARHALMGNLGIQYTYADEDRVEATMPVDHRTRQPFGILHGGATLALGETVAGLGS
                     MILCQPDEIVVGMQVSGNHISSAHEGDTVRAVATIVHKGRSSHVWNVDVFTSTNKLVSS
                     IRVVNSVMKKR"
     CDS             complement(7733..8095)
                     /locus_tag="ctg219_8"
                     /transl_table=11
                     /translation="MVQVRIKRVYEDFSETDGYRVLVDKLWPRGIKKEWLKYDYWAKDI
                     TPSAALRRWFHEDIPGHWNDFVVMYQKELEASQAVADFLTLIKPHPVITLLYASKEPVY
                     NHARILRDYLEMHLKE"
     CDS             complement(8166..8564)
                     /locus_tag="ctg219_9"
                     /transl_table=11
                     /translation="EKDDLSPDEVVESREEEDENKKIFKELNRIVVQDQLYLSPELSRE
                     DLAQIVHLNNARFARMIKENTGTNFNGYINELRINYAIQLLKQHPNYTIRAIADEAGFN
                     STPILYSMFKKKTGMTPYEFKKTQESLG"
ORIGIN
        1 tatcttattt tccacagctt cataccaaaa acgaaaaaag aaagaaaatt ttaggaaatg
       61 ctgattttct tattatatat ttgaagtaaa atgaaaaact acagaatctc aaaataatga
      121 aaatatcttt ttccagacag actaaagaaa gagctttcaa acaactttac gaggattatt
      181 atgccccttt ctgcctgtat gcaaaaagat ttgtagatga taaagaagtc cgcgaggaca
      241 ttgtttcgga tgtattcacc tccctatggg acaagttgga taccgactct ttcgatttgc
      301 aatcagagac agcattggga tatataaaaa tgtgtgtaaa aaacagctgt ttgaactttc
      361 tgaaacatca ggagtatgaa tggagttatg ccgaaaatat ccaaaagaaa gctcctctat
      421 atgaaacaga aacagatagt gtatatacac ttgatgagtt ataccgaatg ctatacgaaa
      481 cattaaataa gcttccggaa aactatcgca ccgtatttat gaaaagtttc tttgaaggca
      541 aaacacatgc ggaaattgcc gaagaaatga atctcagcgt aaaatccatt aatcggtata
      601 aacaaaaaac aatggaactc ctgcggaacg agttgaaaga ttacctcccg ctgtttttat
      661 tattcctgtc tcccgagcaa ctgtaagctc tctgctaaaa cacggcactc tttacgatta
      721 atcttcccat ttcccgtttg aggaatatga tttaccgtat aaatatattt aggacgataa
      781 taagatgcta agactgattc caatttagtc cctagcgcac ttatctccat ctgcccttct
      841 atcaataaag taacagcctg ccccaaacgc cgatccggaa cggaagtgat cacaaacggt
      901 acagggatag acgactgaag taacctttcg atctcttctg cctgcacttt aattcctccg
      961 ctattgatta cattatcctt tcttcccaga atcgtaaaac taccgtccgg ataaatgcgg
     1021 gcaatatcat ttgtctgcag agtatcatcg caaacaagcg gagcattaat catcaaagta
     1081 ttttctgaag acaaaaacaa ctctacggat gaaaaaggat aataacgatc ggatgctgct
     1141 gcgccattca gacggcgaag agcgatgtga gaaagggttt ccgtcatccc gtaagttgaa
     1201 taaacagcat tggacagatt tctgattttt tcctctaaag ccttgtcaac tgctccgcct
     1261 cctataatta aaatctccgt ttgctttaat ttctctttct cttcgggtat ctgaaatgta
     1321 ttatacacct gcaaaggcac catagccgca aaccttaaag gagtgtccac atctgccaat
     1381 ggatgaccgg aagcccgacg tactataaga ttcaacccgg caatcaaaga acggacgact
     1441 accatcatcg ccccgatata gcgaaggttc atacacaata atgccgtttc accctgcttt
     1501 aaatccagaa actcacaagt caggcgtgca ctctgtatca tctgatcttt gcgaacaagc
     1561 aattctttag gtgcccccgt agaaccggaa gtatgtacag tgatcacagg atcatcatta
     1621 aaccattcgt ttagaaaaag atacaagtcc catatagcag aagggtggtt tccctcacct
     1681 tctgctacaa ggctatgtat atcgcccgga gtatattcct ttccctccag caacaaacgc
     1741 tgtttttgtc ggtcgaatat catcatttac aaaaccacaa acaatctttt ctgatttcaa
     1801 gaggcatctc tacattatct gtaaagagta acccggtgcc taacccttgc ggcaatggat
     1861 tctgaaaagt agcacaccat tgagcgatag cattcagacc gatattagac tccagagcag
     1921 aagttatcca ccaaccgata ttcagtttct ccgcttctgc aatccactcc tcgccaccgg
     1981 ctaatccgcc atgaagagaa ggtttgataa taatatattg cggacggata gccgaaagta
     2041 atctttgctt ttcttcccag gtattatagc ctatcagttc ctcatccaaa gctatcggca
     2101 aaggagattc ggaagtaaga cgtgccattt cttcccattg tccggcacga atgggctgtt
     2161 ctatcgaatg taagtccagt tcggacaagc gtttcaattt ctccatcgca tctgttggtg
     2221 agaatgctcc gttggcatct acacgcaatt ctatttcttt agaagaatag tgagagcgga
     2281 tatgttggag taaagccagt tcttcttcaa agttgatggc accgatcttc aactttatac
     2341 agcggaatcc cgcctccatc ttcttctcta tctgagcaag cattctattg aagtcaccca
     2401 tccagataag cccgtttatc ggaatacctg cttccccacg tgagaagggt gtatcccaca
     2461 aagcccagct tccttcaaaa aagtgacgaa tggctgtctc caagccaaaa aggatggaag
     2521 ggtacttgca tagagcttcc atgtccagct tacctccctg attctctacc tgccggcaga
     2581 ttttagccag cacttcctcg taatcgggaa gatcatcaca gctaagattt ggcagaggag
     2641 cgcactcccc gatccctacc caattgggaa attcgggagc agtaaaatga agataccaga
     2701 cttttcgcgt tgtgtatgtg cctcgtgaag ttccggccgg ctgcttgaaa tgaagcaccc
     2761 gcggaataat gtctattttg caatccattg tttaagggaa cttcggatat ttcttaaagt
     2821 taggtttacg tttctccaga aatgcattct ttccttcctg agcctcatcc gtcagatagt
     2881 aaagcaaggt cgcatcccct gccagctcct gaatacctgc ctggccgtcc agttcggcat
     2941 tcaatccggc tttaatcatc cgcaaggcca acggactgag cagcatcatt tcttccgccc
     3001 attgcacata ctcatcctcc agttgctcca atggaactac tttattcacc aatcccatat
     3061 ccaacgcttc ctgcgcattg tatttccggc aaaggaacca tatctcacgt gccttcttct
     3121 gaccgacgac acgagccaga taagaggctc cgaaacctgc atcaaagcta cctacgcgag
     3181 gaccggtctg tccgaagatc gcattctccg aagcaatcga taaatcgcaa actacatgaa
     3241 gcacgtgtcc gccaccaatg gcaaatccat ttacggcagc aattaccggt ttcggaatgc
     3301 tgcggatttg tttctgtaca tccagaacac tcagacgggg aacaccgtcc ttgccgatat
     3361 agccgccacg ccctttcaca ttctggtcac cgcacgaaca gaaagccttg tcaccagctc
     3421 ccgtaatcac gatcacatca atatccgctt cttcccggca aatgcgcaat gcgtcactca
     3481 tttcagccgt tgtagtcgga gtaaatgcat ttcgatagcg ttcacggtta atggtgatgc
     3541 gggcaatccc attatagtaa tcaaagagga tatcttcgta ttctctgatg gttgtccatt
     3601 ctctttgtgt tgacataatc tatttttgtt ttagttgatg ataataatct ttcagtatac
     3661 gtgcatcttt atttttattg ctgaatactt ccatcagaac cggttgttcc atggcttccg
     3721 gttgtgtgaa ggttttcatc gcttcggcaa gctgttcttc attctctacc cgttgataaa
     3781 ggaatccgcg ttcttccgcc catcctttgg cagatgtctt gtgaacggct gtaatatact
     3841 tgtgcgatgt acccgacata tccagtccgg gtaatgtatg gaaaatctcc cctcctccgt
     3901 tattcagcaa aagaatgcgt agattgggac ggacattgat gttccacaaa gcattcatat
     3961 cataaaagaa actaaggtca cctataacta taaaatttag tttatccgaa ccggcggcat
     4021 atcccactgc cgtggacaac gagccttcga tgccgcttgt accccgatta cagcatacct
     4081 caatcgtaga aggaacctgg tataactgag catagcggat aacagaacta tttgccagat
     4141 gcaatgcaca tgattccggc aatgctttta tcaaagcacc gatagccgac atttccgaat
     4201 atccgaactc cggttcggga atggtcttgc aataattctc ccatacacgg ggatactccg
     4261 gcacgcggtt atccagcaat ggagctattt tctccagaaa ctcaaacggg tccatttcga
     4321 tgacggtagt cagagaaccg taaaggtcaa ccacttctcc atcagcagac acatgccaat
     4381 gttctttagg cggatgctgc cgaagatatt ttttcaaccg cttggaaacc acatgtccgc
     4441 cataagtaat caataactcg ggagtcatct ggccggtttt ctcttcgggc atcgcataaa
     4501 gcgccgcatc aaaattcttc actggaatac cgggtactgt ctgattaccg atatgctcgg
     4561 tcagccacac gaaatgttta tataacaatt tggtatgccg tttctcaaac aagtaaatca
     4621 agttcatctg tccgacaata atcatccgct tctgatatct gttcaagcgt tcgatcaggt
     4681 cattgtaatc ccggtcgtat acattcagcc cctgatagcg cgtaatgaca cgtacttcgg
     4741 gaagcgactc caccgtaaac tggaacaaag gttcggatat aggaatatta atatgtaccg
     4801 gaccttttcc atgatggttg gtttccagca aggcttcatt caccaagcgg ttacagtacc
     4861 attcatcctc ttctgtctga atctccggaa ggtttaccga cttcttcacc aatgtctgaa
     4921 aaacaccggg ctgcggcaat gtctgtcccg ccatctgtcc aatccaggca gcaggccgat
     4981 cggcagagat aacaactaaa ggtatattct gataatacgc ttctgccaca gcaggatgaa
     5041 gattgagcaa cgctgtaccg gaagtacagc aaacggcagc aggatgcccg ccattcagcg
     5101 caagaccaat cgcaaaataa ccggcactcc gttcatccgt catagcataa caagtaaaac
     5161 ccggatgagt agacagcgta tgcacaatag gtgcattacg gctaccggga cataacacta
     5221 ctttcgtaat tccatgcgcc tcaagcagcg cgaccaactg gagtatattt ttcttgtccg
     5281 aatacatatt gatagtgatt agcttgttag tgattcatca ttattggagc agacacaaga
     5341 atacgcctca tggtctgcaa tttcttttcc gtttcctgcc attcatcatt caactctgaa
     5401 gaggctaaca atccgccacc ggcatacagt gtcaattgct cgtcttcaat gtgcatgcaa
     5461 cgcagattca catacaaatc tgtgcgtccc tccggatcga gccaaccgat aaaaccggaa
     5521 taatacttac gatcgtaccc ttcattttcc aaaatgaacc ggtaggcttc ttctttaggc
     5581 agtccgcaca cggcaggagt cggatgcagg actttcagaa ggtctcccag atttttatta
     5641 tctttcaaag agaaatggaa atcagttttc agatgtgaca aggcaccggc ataagccgga
     5701 taaggtccgc tctctgtgga gcgaatgccc agcgaaagaa gctgccgacg gatataggac
     5761 gccacataat cctgctcctg acggtttttg tcatcccata cttgcggaag tttaccattc
     5821 tgcaaaggtt gagttcctgc cagggcaact gtgttccatt catttttttc gcccgacaat
     5881 ataatttcgg gggtacttcc cagccacacg cccgtctgag gagtataaca cagatagata
     5941 taggaatgaa tataacgttg acaagctgca cgaaaaacag ctgaagggga aaactccgga
     6001 ttctttccaa tagtgagact acgggaaagc accagtttat caaaggtagc atcacgcaag
     6061 gcttcaataa atgtatgaaa acaggtcgca tacttcccag tacaaagggt atgaaaagat
     6121 tcctccggat aactttgcaa gtcctgctct tcctctgcca cgatttccat aggcaacggt
     6181 tgtccagtcc tgtcggactg tatcaacaca atcggacatg acttatctat acggaacgga
     6241 gcaatcacaa atcctctttg tccattcagt tctttcaaat cgaaaatcaa gcggacagct
     6301 ccgacatctt ctgtcaacag acgaggatac ttctccccgg gaacacgata aacagcaaag
     6361 ggctgtttcc gctgaataag tgcatcaata gttgtcaagt tacttttttc gtcaatcatc
     6421 tttttttcat cacactgttg accacccgta tagaggacac cagtttattg gttgaagtaa
     6481 aaacgtccac attccataca tgggaggaac gtcctttgtg tacaatcgtc gctactgcac
     6541 gtactgtatc accttcgtgc gcagaagata tatgatttcc gctgacctgc attcctacca
     6601 caatttcatc cggctgacag agaatcatcg agccgagtcc ggcaactgtt tctcccaatg
     6661 caagcgtagc tccaccgtgc aaaataccga acggctgacg ggtacggtga tctaccggca
     6721 tcgtcgcctc tacacggtct tcgtcggcat atgtatattg gatacccaga ttacccatca
     6781 atgcgtgacg cgcctgtgca ttcaactggt ccaaaggaat ctctgcagcg cgaacttccg
     6841 ctattatcgc cttttcgaca gccagagcca ctccgtcttc ctcattggaa gctgtcacat
     6901 aatccgcaca gacctttacc gaatcctgcg aatgccccat cgccactccc agtcctgcca
     6961 gctgaatcat cgttacatcg cacacaccgt ctcctatagc gatgacttct tcacgcttca
     7021 catccagttc ttccaataaa gctcccaatg tgttggcttt atcaatcgca cacggcacta
     7081 cttccagaaa ataaggttcg gaacggaaaa catccaaagc tccgttcaac cgtctcttcc
     7141 agtgtccttc cagactaacc aacgcttcct cgtcatcgct gacaagcata cacttacacg
     7201 gagcaaagtc aattgctaca gaaaattcct cttccttgat cactttcaaa ttattcaagc
     7261 gagcttcatt ctggatatgt tcattctccg gagtgtcagt aatgatcgta tcatcatggt
     7321 aagtgaacag tgcgaaatta ttttttcttg ccttcttttc cagataaggc aacatttccg
     7381 gattaatcct ccgctcaaac agtatttctc cgttttgagc attaattatc tggcaaccat
     7441 tataagaaag gatataacct ccataatttc cgagttctag ggatttggct aaaggcatca
     7501 gaccgtaagt cggtcggccg gatgccaaca cgatacgtac tcccatctgc tgaactttca
     7561 gcaaagcagc caatgtacgt ttactaattt cttttgcatc attgagaagc gttccgtcta
     7621 catcaagaac taataattta tacttcatgg acacacgatt ttgatttaga ttacaaaggt
     7681 aggaaattga gtgaacgact gaaagcggaa agagataaaa attactttaa tttcactctt
     7741 tcagatgcat ttccaaataa tcacgaagga ttcgggcatg attataaacc ggttctttgg
     7801 atgcataaag caaagtgatc accggatgag gtttgataag agtcagaaaa tcggcaacag
     7861 cttgagaagc ttccagttcc ttctgataca ttacgacaaa atcattccag tgacccggaa
     7921 tatcttcatg aaaccatctg cgcagtgctg cggaaggcgt tatatctttt gcccagtaat
     7981 catatttcaa ccattctttt ttgattccac gtggccagag tttatctacc agcacccgat
     8041 atccgtcggt ctctgaaaag tcttcgtaca ctcgctttat cctaacttgc accatttccg
     8101 tttatattta gttatcataa gaataaaccg ataaaacgga aaattgttta tcgaaaaagc
     8161 caaaatcaac ctaaggattc ctgcgttttt ttaaattcgt aaggagtcat accagtcttt
     8221 ttcttgaaca tactgtacag aataggcgta ctattaaatc cggcttcatc agctatcgca
     8281 cgaatggtat aattgggatg ttgcttcaat aactgaatcg catagttaat acgaagttca
     8341 ttaatatacc cgttgaaatt agttccggtg ttttccttga tcatccgggc gaaacgcgca
     8401 ttattcaaat gtacaatctg agccagatcc tctctcgaca attccggaga cagatataac
     8461 tgatcctgaa caacaatacg attcagttct ttgaaaattt tcttattctc atcctcttcc
     8521 tccctactct ccactacttc atccggagat aaatcgtctt tttcgg
//
