LOCUS       c00023_gnlPro..        11863 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|PAHHILEL_23.
ACCESSION   c00023_gnlPro..
VERSION     c00023_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-07 15:30:15
            Original ID  :: gnl|Prokka|PAHHILEL_23
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 11863
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..11863
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[1313:11329]"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and (minimum(2, [ACD1_car,
                     ACP_syn_III_C, AcetylCoA_hyd_C, AcetylCoA_hydro,
                     Acyl-CoA_dh_1, Acyl-CoA_dh_2, Butyrate_kinase,
                     CT_Propionyl_CoA1, CT_Propionyl_CoA2, CT_Propionyl_CoA3,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_2_CAF, CoA_trans_6_Glutaconate, E1_dh, ECH_1,
                     ECH_2, HBT, HBT_2, HCDH, HpaB, Ketoacyl-synt_C, Thiolase_C,
                     Thiolase_N, adh_short, adh_short_C2]) or FA_synthesis) and
                     not (PFL-like or PFL_6_pcresol or PFL_9_tma or Gly_radical
                     or Gly_430_pcre or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and not
                     (POR or POR_N))"
                     /neighbourhood="10000"
                     /product="TPP_fatty_acids"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      1314..11329
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and (minimum(2, [ACD1_car,
                     ACP_syn_III_C, AcetylCoA_hyd_C, AcetylCoA_hydro,
                     Acyl-CoA_dh_1, Acyl-CoA_dh_2, Butyrate_kinase,
                     CT_Propionyl_CoA1, CT_Propionyl_CoA2, CT_Propionyl_CoA3,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_2_CAF, CoA_trans_6_Glutaconate, E1_dh, ECH_1,
                     ECH_2, HBT, HBT_2, HCDH, HpaB, Ketoacyl-synt_C, Thiolase_C,
                     Thiolase_N, adh_short, adh_short_C2]) or FA_synthesis) and
                     not (PFL-like or PFL_6_pcresol or PFL_9_tma or Gly_radical
                     or Gly_430_pcre or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and not
                     (POR or POR_N))"
                     /neighbourhood="10000"
                     /product="TPP_fatty_acids"
                     /protocluster_number="1"
     cand_cluster    1..11863
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TPP_enzyme_C and (minimum(2, [ACD1_car,
                     ACP_syn_III_C, AcetylCoA_hyd_C, AcetylCoA_hydro,
                     Acyl-CoA_dh_1, Acyl-CoA_dh_2, Butyrate_kinase,
                     CT_Propionyl_CoA1, CT_Propionyl_CoA2, CT_Propionyl_CoA3,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_2_CAF, CoA_trans_6_Glutaconate, E1_dh, ECH_1,
                     ECH_2, HBT, HBT_2, HCDH, HpaB, Ketoacyl-synt_C, Thiolase_C,
                     Thiolase_N, adh_short, adh_short_C2]) or FA_synthesis) and
                     not (PFL-like or PFL_6_pcresol or PFL_9_tma or Gly_radical
                     or Gly_430_pcre or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and not
                     (POR or POR_N))"
                     /kind="single"
                     /product="TPP_fatty_acids"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..11863
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="TPP_fatty_acids"
                     /region_number="1"
                     /rules="(TPP_enzyme_C and (minimum(2, [ACD1_car,
                     ACP_syn_III_C, AcetylCoA_hyd_C, AcetylCoA_hydro,
                     Acyl-CoA_dh_1, Acyl-CoA_dh_2, Butyrate_kinase,
                     CT_Propionyl_CoA1, CT_Propionyl_CoA2, CT_Propionyl_CoA3,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_2_CAF, CoA_trans_6_Glutaconate, E1_dh, ECH_1,
                     ECH_2, HBT, HBT_2, HCDH, HpaB, Ketoacyl-synt_C, Thiolase_C,
                     Thiolase_N, adh_short, adh_short_C2]) or FA_synthesis) and
                     not (PFL-like or PFL_6_pcresol or PFL_9_tma or Gly_radical
                     or Gly_430_pcre or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and not
                     (POR or POR_N))"
                     /tool="gutsmash"
     CDS             2..436
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) OAD_beta"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg23_1"
                     /sec_met_domain="OAD_beta (E-value: 3.8e-67, bitscore:
                     216.2, seeds: 229, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LMLGNFLRECKVTERLVHASQNELINIVTIFLGTSVGLTMQGDRF
                     LQSETLLIILLGIVAFGVATAGGVIAAKIMNLIWRKNPVNPLIGSAGVSAVPMAARVSH
                     NVGQKYDPSNYLLMHAMGPNVAGVIGTAVIAGYYIATLAK"
     CDS             474..1253
                     /locus_tag="ctg23_2"
                     /transl_table=11
                     /translation="MNSAASFSTPPEEEGPCGDWTYHEWAEAFSTNDLARTLPPGHIAV
                     CRVQTGGRGRFNRKWIGEEGGLWASFTVPLSAPEDTAADVHWGHLPLVAGLALFNMLRG
                     MGLDSVRLRWPNDLLAGKSKLAGILVERPAENMAVIGIGINVFNDVSSIAGEIKDPPAR
                     LADLVRDCPSLHAVMASLGSHLNQVLSVFSHGGVPALQEGLSRAWAGERPVSILTDDET
                     VRGIFTGIDDQGNPVLSLPAGTVRTIPAHLINRLLEE"
     CDS             1314..2810
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_fatty_acids: AcetylCoA_hydro"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_fatty_acids: AcetylCoA_hyd_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg23_3"
                     /sec_met_domain="AcetylCoA_hyd_C (E-value: 6.2e-47,
                     bitscore: 148.9, seeds: 181, tool: rule-based-clusters)"
                     /sec_met_domain="AcetylCoA_hydro (E-value: 4.4e-44,
                     bitscore: 140.4, seeds: 5, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSYKVLTPEEAASLIKHGHHIGLSGFTPAGTAKAVTAALAKIAEA
                     EHEKGNPFQVSVFTGASTGDSCDGILSRAKAIRYRAPYTTNVDFRKAVNNGEIAYNDIH
                     LSQMAQEVRYGFMGNVDIAIIEACEVTADGKIYLTAAGGIAPTICRLADKIIVELNAAH
                     SKSAMGLHDVYEPLDPPYRREISIFKPSDRIGKPYIQVDPKKIVGVVETNWPDEARSFA
                     AADPLTDKIGQNVADFLAADMKRGIIPSTFLPLQSGVGNIANAVLGSLGRDKTIPAFEM
                     YTEVIQNSVIGLIREGRVKFGSACSLTVTNDCLEGIYRDMDFFRDKLVLRPSEISNSPE
                     VIRRLGVISINTAIEADIYGNVNSTHIGGTKMMNGIGGSGDFTRNAYISIFTCPSVAKD
                     GKISAIVPMVSHHDHTEHDVNIIITEQGVADLRGKSPKERAQTIIENCVHPDYKNILWD
                     YLKLSDGKAQTPQSIRAALGMHAELARSGDMKNVDWAQYK"
     CDS             2929..3630
                     /locus_tag="ctg23_4"
                     /transl_table=11
                     /translation="MNWMIYPAARAFIKVCSVLFGAGAAAAVLIHLFMPFFLRSPRTAA
                     PFLLLGTGAELLSILSLSFLMFWGVRVLLASRGSRITRNLSMLAFLPALYALLIPFAGM
                     PVPSQYTEMDRVWEAVLLLAAVTSFFSFPYTAGYGAAGRRLFLAWGIAAAGCGLQSALF
                     FLAVLLRQFLSTAVPSLAAPVAWLAVLLSCGLEIMLATLSAILAQRLFKEVMSIASMPE
                     PIDPSMPGNRP"
     CDS             complement(3848..4711)
                     /locus_tag="ctg23_5"
                     /transl_table=11
                     /translation="MKGIVLAGGSGTRLHPVTLSVSKQLLPVYDKPMVYYPISVLMLAG
                     IREILVISTPRDLPLYRDLLGDGSRFGVSFEYREQPRPEGLAQAFIIGEEFIGKDSVAL
                     VLGDNIFYGRGLTEKLRRAAELTSGATIFGYQVHDPQRFGVVEFNEEGKAVSIEEKPLR
                     PKSDIAVTGLYFYDNRVVEIAKRIPKSSRGELEITSVNQEYLKQGLLRVEKLARGYTWL
                     DTGTHDTLLEASMFVRTLEHHQGFKVACLEEIAFNNGWISQETLRSQAGAMNNNGYGRY
                     LDELVK"
     CDS             complement(4721..5773)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GDP_Man_Dehyd"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg23_6"
                     /sec_met_domain="GDP_Man_Dehyd (E-value: 1.1e-98, bitscore:
                     320.2, seeds: 258, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKVIVTGGAGFIGSNLVRLLLERGHEVLNIDALTYAGNIHSLDGS
                     ADSPAYRFLHADVRDASLMRRTLREYAPDWVMHLAAESHVDRSIDDPGNFMTTNVMGTF
                     SMLQAALEYYRSLEGEKKERFRFHHISTDEVYGSLGKEGLFTESTPYRPHSPYSASKAS
                     SDHLVRAWHDTYGLPVLITNCSNNYGPCQFPEKLIPVVILKALGGEPIPVYGKGENVRD
                     WLYVGDHCEALLTVVSCGKPGETYNIGGNNEKTNLELVELLCSHLDELRPRPDGRSYRE
                     QISFVQDRPGHDLRYAIDASKIRRELGWTPRQDHSSGFRKTIQWYLDHEEWWRGILSGE
                     YRLERLGTNG"
     CDS             complement(5905..6849)
                     /locus_tag="ctg23_7"
                     /transl_table=11
                     /translation="MTSGGDAAGMNPAIKAAVDHARQLGMNPYVVYDGLEGLIDGKIKE
                     ATRELTNDMIYRGGTLLRSSRSKRFFDYEFRKQAYEHLKERNIDKLIIMGGDGSFRALN
                     DFFNDFEVPFAGIPATIDNDIAGTDYCLGVDTAQNVILDCIDSVRDTARSHHRAFVIET
                     MGRDCGYLAMTTALCSAADICIVPEIPYDLESIYKRLQPVINEEGSCIIAVVAEGTRVA
                     QYLTRWLTERAGMDTRLTVLGHVQRGGSPTARDRLMGTRFATRAVEALNNGDINQIMVY
                     HDGQYGYASLDSVAGQQYSVNQDIINLCRELSC"
     CDS             6978..7709
                     /locus_tag="ctg23_8"
                     /transl_table=11
                     /translation="MNDTAAAILKATAALRDGTEKLRFESPVHVTYNPLTYAWGPHEQY
                     VRTYGNGEKGHLFLGMNPGPFGMAQTGVPFGEVDAVVNWLHIRGEVGRPEHTHPKRPVE
                     GFGCPRSEVSGRRLWGLFAEAFGTAENFFRHNYVANYCPLIWMGATGANITPDKLPAEQ
                     RAAVDAVCMEHLLSLITILNPHTLVGVGAYATQKLRDAASRLPGKSFTIGTLLHPSPAS
                     PIANKLWPERPIQQLKELGIL"
     CDS             8078..9544
                     /locus_tag="ctg23_9"
                     /transl_table=11
                     /translation="MAISDYIVTIGLEVHCQIKTKSKMFCSCETGFGFEPNTRVCPTCL
                     GLPGALPVLNEFAIERTLLTGLMLGCSSPEISQWDRKNYFYPDMAKNYQTSQLDLPLCL
                     GGEVPLYPWSYPNDVIKAGVPPFRTVKLTRIHLEEDAAKITHHANYSLIDYNRAGSALM
                     EIVSEPDIDTPEEAYAYLKSLQQILNYGDISDADMEKGQMRCDVNISLRPHGQKELGAK
                     VEMKNINSMSAVRRALHYEIQRQAEELDMGIPQIQSTRRWDDERGESVVMRTKEDAHDY
                     RYFPCPDLVPVRTAPLVEKVRGQIPELPQERQKRFMEGYGLSEYDANVLVGDLELARFF
                     EEAARGTASGKKIANWVINNISAVLNEKGMRPSECPVKPGAIRELIAIIDDGTVSNNQA
                     KDVFAKMWDEPALAAAQAAKLLGFEKADSSFLDGIVREVISANPDKVAEIQGGNEKLLN
                     WLTGQVMKAAKGKANPKIVTEALKKALSME"
     CDS             complement(9599..11329)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_fatty_acids: TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg23_10"
                     /sec_met_domain="TPP_enzyme_C (E-value: 1.9e-34, bitscore:
                     108.2, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MHRVADQIVEILEKAGVKRIYGIVGDSLNPVTDALRRRKTIEWIH
                     VRHEEVAAFAASAEAQLSGNLAVCCGSSGPGNLHLINGLFDAHRNHAPVLAIASHIPQS
                     QVGMEYFQATHPEQLFKECSAYAELVSEASQAPSILMSAIQHAWARRDVGVVVLPGDIA
                     DAPAEMKNLVHPPSYTRENVVPEHESVSLLARMLDDHRRITFFCGAGCAGAEDRVVRLA
                     HRLKAPIAYTWRGKDYFEHDNPLGIGMTGLLGWGDAYKAMHESDMLVLWGTDFPYFNFI
                     PTKPEIVQIDRRGEVLGRRCRLDLGICGDVSVTAEALLNMVQEKTDSGHLDAALKRHAR
                     DVKEMNAYMEGNDKESPIRPEQLTTALNRHAASDAVFTVDTGTPCIWSARFLCATPGRR
                     TLASFNHGSMANAMPMAIGAQMEYPERQVIALCGDGGLSMLLGDLITIVQYRLPVKIVV
                     YNNDCLDFIQLEMQAAGLIPWQINLNNPSFAAVADAVGIKGFLLDKSSQVDQMVDMFLN
                     YPGAALLDAHVDRDALALPPYISMGQAADFSLAMMKQTLAGEVKQVWNTLAGNRKLFKP
                     "
     CDS             complement(11494..11862)
                     /locus_tag="ctg23_11"
                     /transl_table=11
                     /translation="NTSTGSFSQNRGDVSETPVVLEGGLLNVTLAVTGANQSQSVEVYV
                     NGSLFDTLSYNGNMNGNRTDIQSWINPNLTWGEIQWTDTKLSAEQIAGFAGLQVPEPAS
                     ASLGILGLAVLMMRRRRS"
ORIGIN
        1 gctgatgctt ggcaacttcc tgcgcgaatg caaggtgacg gaacgcctgg ttcatgcctc
       61 ccagaacgaa ctcatcaaca tcgtcaccat cttcctggga acctccgtgg ggctcacgat
      121 gcagggcgac cgcttcctgc agtcggaaac gctgctgatc atccttctgg gtatcgtcgc
      181 cttcggcgtg gcaacagcgg gcggagtgat tgccgccaag attatgaacc tcatctggcg
      241 caagaatccg gtcaaccccc tgatcgggtc cgcaggcgtc tccgccgtcc cgatggcagc
      301 ccgcgtctcc cacaatgtgg gccagaagta cgacccctcc aactacctgc tcatgcacgc
      361 catgggcccg aacgttgcag gcgtgatcgg caccgcagtc atcgcgggct actacatcgc
      421 cactctggcg aaataaccag aattgaaaat tactcccggc ctcggcccgt cccatgaatt
      481 ccgcagcctc attttccacc cctccggagg aggaaggacc atgcggcgac tggacttatc
      541 atgaatgggc tgaggctttt tccaccaatg atctggcccg caccctcccc ccggggcata
      601 ttgccgtctg ccgtgttcag acaggaggcc gcggcaggtt caaccgcaaa tggatagggg
      661 aggaaggcgg cctgtgggca tccttcaccg tccccctgtc cgctcctgag gatacagcgg
      721 ccgacgtgca ctggggccat ttgcctctgg ttgcggggct ggccctgttc aacatgctcc
      781 gcggcatggg gctggattcc gtgcgcctgc gctggccgaa cgacctgctg gcgggcaaat
      841 ccaaactggc gggaatactg gtggaacgcc cggcggagaa catggccgtc atcggcatcg
      901 gcatcaatgt tttcaatgat gtatcctcca tcgccgggga aatcaaggac cctccggcaa
      961 ggctggcgga tcttgttcgg gactgccctt ccctgcacgc cgtcatggct tccctgggca
     1021 gtcatttgaa ccaggttctt tccgtctttt cccacggtgg cgtccccgcc cttcaggagg
     1081 gtctgtcccg ggcatgggcc ggagaaaggc cggtttccat tcttacggat gacgaaaccg
     1141 tccggggcat ttttacaggg attgacgatc agggcaatcc tgtgctatcc cttccggccg
     1201 gcaccgtccg caccattccg gcgcacctga tcaacaggct cctcgaagaa tgagcctgcc
     1261 gctccgtttt acacggggtt tctttctttt ttcatccaac aaaaatcact gacatgagtt
     1321 acaaggtact gacaccagaa gaagcagcaa gcctgatcaa gcatggccac catattgggc
     1381 tgagcggatt cacgcccgcc ggaacggcca aggccgttac ggctgcgctg gcaaaaatcg
     1441 cagaagcgga acatgagaag gggaaccctt tccaggtgag cgtcttcacc ggtgcttcca
     1501 ctggcgattc ctgcgatgga atcctttccc gggccaaggc aatccgctac cgcgctccct
     1561 acaccaccaa cgttgatttc cgcaaggcgg tgaacaacgg ggaaatcgcc tataatgaca
     1621 tccatttgtc ccagatggcc caggaagtgc gctacgggtt catgggcaac gtggacatcg
     1681 ccattattga agcctgtgaa gtcacggccg acggcaaaat ttacctgacg gccgcgggcg
     1741 ggatcgctcc caccatctgc cgcctggcag acaaaattat cgtggaatta aacgccgccc
     1801 acagcaagag cgccatgggc ctgcacgacg tttacgaacc cctagatcct ccctaccgcc
     1861 gcgaaatctc catcttcaaa cccagcgacc gcatcggcaa gccgtacatc caggttgacc
     1921 cgaaaaagat tgtgggcgtt gtggaaacca actggccgga tgaagcccgt tccttcgccg
     1981 cagcggatcc cctgaccgat aaaatcgggc agaacgtggc cgatttcctg gctgccgaca
     2041 tgaaacgggg catcattccc tccacgttcc tgcctctcca gtccggcgta ggcaacatcg
     2101 caaacgcggt gctgggctcc ctgggccgcg acaagacaat tcccgcgttc gagatgtaca
     2161 cggaagtcat ccagaattcc gtcatcggcc tgattcggga gggccgcgta aaattcggca
     2221 gcgcctgctc cctgaccgtg acgaacgact gcctggaagg catttacagg gatatggact
     2281 ttttccgcga caaactggtg ctccgtccct cggaaatatc caacagcccg gaagttatcc
     2341 gccgtctcgg cgtcatctcc atcaacaccg ccattgaagc cgacatttac gggaacgtca
     2401 actccacgca cattggcggc acgaagatga tgaacggcat cggcgggtcc ggcgacttca
     2461 cgcgcaacgc ctacatctcc attttcacct gcccgtccgt tgccaaggac ggcaagatca
     2521 gcgccatcgt ccccatggtt tcccaccatg accatacgga acatgacgtc aatatcatta
     2581 ttaccgagca gggggtcgcg gacctgcgcg gcaagagccc gaaagaacgg gcccagacca
     2641 ttattgaaaa ctgcgtccac ccggattaca aaaacatcct ctgggattac ctgaagctgt
     2701 ccgacggcaa agcccagaca ccgcaatcca tcagggccgc tttgggcatg cacgccgaac
     2761 tggccagaag cggagacatg aagaatgtcg actgggccca gtataagtaa ttccgcatgc
     2821 cgtcattcgc attggcatcc atgaattcac gttaacccct caggaccgct tccgcaaagg
     2881 gagcggtcct tttccttttt cccatcccct ctactccttc tcttcaccat gaactggatg
     2941 atttacccgg cagccagggc tttcatcaaa gtctgctccg ttcttttcgg cgcgggcgca
     3001 gcagcggcag tcctcatcca tctgttcatg ccttttttcc tccgctctcc ccgaacagcc
     3061 gcgcccttcc tgcttttggg aacaggggcg gaactgctct ccatcctttc cctgtccttc
     3121 ctcatgttct ggggcgtcag agttctgctg gcctcccgcg gaagcagaat aacaagaaat
     3181 ctgagcatgc tggccttcct gcccgccctg tacgccctcc tcattccgtt tgcgggcatg
     3241 cccgtcccat cgcaatatac ggaaatggac agggtttggg aggccgtcct ccttctggcg
     3301 gccgtcactt ctttcttttc cttcccttat acggcgggat acggtgccgc aggcaggaga
     3361 ttattcctgg cctggggcat cgcggcggca ggctgcggtt tgcagagcgc cctgtttttt
     3421 cttgccgtcc tgttgcgtca gttcctgtcc accgcagttc cctccctggc agcgcctgtt
     3481 gcatggctgg ccgttcttct gtcctgcggc ctggaaatca tgctggcgac cctttccgct
     3541 attctggcgc agcgcctgtt taaagaggtc atgtccatag catccatgcc ggaaccgatt
     3601 gatccttcca tgccgggcaa ccgtccctga ctttcctccc ctccgttttt accggcctgc
     3661 cggaagagca ccctcattcc ccggcatgaa aggcttttac ggctttgcgc aaaaagccgt
     3721 ccggaaattt ccgccggtgg aacggaatcc gtatggaaag cattgccgga aagcaacccg
     3781 ccccaccccg gaaagccgcg ggttcgcagg aacacccctc ccgtttccac tccggcggca
     3841 gacagcccta tttcaccaat tcatccagat aacggccata accgttatta ttcatggctc
     3901 cggcctggga gcgcagcgtt tcctgggaaa tccagccgtt attaaaggct atctcctcca
     3961 ggcaggctac cttgaacccc tggtggtgct ccagagtacg aacgaacatg gaagcctcca
     4021 gaagggtatc gtgcgtgccc gtatccagcc acgtataacc gcgcgccagt ttttccacgc
     4081 gcaacaggcc ctgcttcagg tattcctgat tcacagaggt gatttccaac tcgccgcggg
     4141 aagacttggg aatccgtttg gctatctcca ccacccggtt gtcgtaaaaa tagaggcccg
     4201 tcaccgcaat atccgatttg ggcctgagcg gtttttcctc aatggaaacc gccttcccct
     4261 cctcattgaa ttccactacc ccgaaacgct gcgggtcatg cacctggtaa ccgaaaatgg
     4321 tcgctccgct cgtcagttcg gcggccctcc tcagcttctc cgtcaggcca cgcccgtaaa
     4381 aaatattgtc ccccagcacc agggcaacgg aatcctttcc tatgaactcc tctccaataa
     4441 taaaggcctg agccagcccc tccggcctgg gttgttccct gtattcaaag gaaacgccga
     4501 acctgctgcc gtcccccagc aaatcccggt acaggggcag atcccggggc gtggaaataa
     4561 caaggatttc ccgtatcccg gccagcatca gcacggagat gggataataa accatcggct
     4621 tatcataaac gggcagcaat tgcttgctga cggaaagcgt aacgggatgc agacgcgtgc
     4681 cgcttccccc ggccagaaca atacccttca tatcaaattc ctagccattg gttccaagac
     4741 gttccaggcg gtattccccg gacaggatgc cccgccacca ttcctcatgg tccagatacc
     4801 actgaatggt ctttctgaat ccggaagaat ggtcctggcg cggagtccac cccaattccc
     4861 tccgtatttt ggaagcgtca atcgcatagc gcaggtcatg gcccggcctg tcctgcacaa
     4921 aggagatttg ctcccggtag ctccggccgt ccggccgggg ccgcagttca tccagatggg
     4981 aacacagcag ctccaccagc tccagattgg ttttctcgtt attgccgccg atgttgtacg
     5041 tttcccccgg ttttccgcag gaaacgaccg tcaacagagc ctcgcagtga tcccccacat
     5101 acagccagtc ccgcacgttt tcccctttgc cgtatacagg aatgggttcc ccgcccagcg
     5161 ctttcaggat aacgacgggt atcagctttt ccgggaactg gcaggggccg taattgttgg
     5221 aacagttggt gatcagcacg ggcagaccgt acgtatcgtg ccaggcgcgc accaggtggt
     5281 cgctggaggc cttgctggcg gaatacgggg aatgggggcg atacggcgtg gactccgtga
     5341 acaggccttc ctttcccagg gagccgtaca cttcatccgt ggaaatgtga tgaaagcgga
     5401 aacgctcctt tttctctccc tccagggaac ggtaatattc cagggcggcc tgaagcatgg
     5461 aaaaagtgcc catgacgttg gtggtcataa aatttcccgg atcgtcaatg gaacggtcca
     5521 catgggattc cgccgccagg tgcatcaccc agtccggagc gtactcccgc aaagtgcgcc
     5581 gcatcaggga agcgtcccgg acgtcggcgt gcagaaagcg gtatgccgga gaatccgccg
     5641 agccgtccag tgaatggatg ttgccggcat aggtcagggc gtcaatattc aggacttcat
     5701 ggccgcgctc cagcagcagc ctgaccagat tggagccgat gaatccggcg ccgcccgtaa
     5761 cgataacttt catagcactg ttttcaggga aagatgcggc gccatcatac agcagcggcg
     5821 ttttttttca aaacaaatcc gcccatgccg cgggaacgtg gcggcatggg cgggaaaaag
     5881 cgggttccgt aaccgctgag acggctagca gctcagctcc cggcaaaggt tgatgatatc
     5941 ctggttcacg gagtactgct gcccggctac ggaatccagg gaggcatagc cgtactggcc
     6001 gtcatgatac accatgatct ggttgatgtc cccgttgttc agagcttcca cggcgcgggt
     6061 ggcaaaacgg gtgcccatca ggcggtcacg ggcggtgggg gaaccgccgc gctgcacatg
     6121 gcccagcacg gtcaggcggg tatccatgcc ggcgcgttcc gtcagccagc gggtcaggta
     6181 ctgcgccacg cgggtgcctt ccgccaccac ggcaatgatg cagcttcctt cctcattgat
     6241 gacaggctgg aggcgcttgt aaatggattc caggtcatac ggaatttcag ggacaatgca
     6301 gatatccgcc gcgctgcaaa gagcggtggt catcgccaga tagccgcagt cccggcccat
     6361 cgtttcaatc acgaaagcgc ggtgatggga acgggccgta tcacgaacgg aatcaatgca
     6421 atccagaatc acgttctggg ccgtatccac gcccaggcag tagtccgtgc cggcaatgtc
     6481 gttgtcaatc gtggccggaa taccggcaaa aggcacttca aaatcattga aaaagtcgtt
     6541 cagggcgcgg aaggaaccgt ccccgcccat gatgatgagc ttgtcgatgt tgcgttcctt
     6601 cagatgttcg taggcctgct tgcggaattc gtagtcgaaa aagcgcttgg atcgtgagga
     6661 acggaggaga gttccgcccc tgtagatcat atcgttggtc agttcccggg tggcttcctt
     6721 gatttttcca tcgatcagcc cttccaagcc gtcataaaca acgtacgggt tcatcccaag
     6781 ctggcgggca tgatccactg ccgccttgat cgccgggttc attccggcgg catcgccgcc
     6841 agatgtcata atggctattc cactcataag taataaggtt aacttgtccg gggggagatg
     6901 ttaccgggcg gaacaaataa tgcaagcgcg gagtttttac tggcgcaata aacggcaacg
     6961 cttcatgatg cggaggcatg aacgacactg cagcagccat tctgaaagcc acggccgccc
     7021 tccgggacgg cacggagaag ctccggttcg aatccccggt ccatgttacc tacaaccctc
     7081 tcacctatgc atgggggccg catgaacagt atgtgcgcac ctacggaaac ggggaaaagg
     7141 gccatctgtt cctgggcatg aatcccggcc ccttcggcat ggcccagaca ggcgtcccct
     7201 tcggggaagt ggacgccgtc gtcaactggc tgcacatccg cggagaagtc gggcggccgg
     7261 aacataccca ccccaaacgt cccgtggagg gcttcggctg ccccaggtcg gaagtcagcg
     7321 gccgccgcct ctggggactt ttcgcggaag ctttcggcac tgcggaaaac ttcttccgtc
     7381 acaattacgt ggccaattac tgtccgctga tctggatggg agccaccgga gccaacatta
     7441 cgccggacaa actgccagcg gaacagcgcg ccgccgtgga cgcggtatgc atggaacacc
     7501 tgctttccct catcaccatc ctgaatcccc acacgctggt gggtgtgggt gcctacgcca
     7561 cgcagaagct gcgggacgcc gcctcccggc tccccggcaa aagcttcacc atcggcacgt
     7621 tgctccaccc aagccccgcc agccccatcg ccaacaagct ctggccggaa cgccccatcc
     7681 agcagcttaa ggaactgggc attttataaa aagagcggag gaggtagagt ggaaagctcc
     7741 gtgacatgga aggaatcacc agagcgacag gccggaaatc ggcagttcat cttgttctcc
     7801 tccaaatcta catcgttttg aaggaatatc cggccccctt tactggcttg atttgcccag
     7861 ggacacggcc ttcctgacgg aagaaaagca cgccggcatc taccgggacg gagaagaact
     7921 taaacgcctc cccacttcca ccacaaaaat cagcctccct ccaaatcaat catcattctt
     7981 agactgaaaa ccctccgctc tcccccgcag gcctttttac tggacagggg gaaaagggtt
     8041 ccgtacagtt tccgcgatct tcaagcgttc cgaatttatg gcaatttcag attacatcgt
     8101 gaccattggc ctggaagtcc actgccagat caagacaaag agcaaaatgt tctgctcctg
     8161 cgagaccggc tttggctttg aacccaatac gcgcgtgtgc cccacctgcc tggggctgcc
     8221 gggcgccctg cccgtcctga atgagttcgc cattgaacgc acgctgctga ccggcctgat
     8281 gctgggatgt tccagcccgg agatttccca atgggaccgc aagaattatt tctatccgga
     8341 catggctaaa aattaccaga cctcccagct ggatcttccg ctgtgcctgg gaggggaagt
     8401 gcccctgtac ccctggtcct atccgaatga cgtgatcaaa gccggcgtcc cccctttccg
     8461 caccgtgaag ctgacccgca tccatctgga agaagacgcg gcgaagatta cccatcatgc
     8521 caattattcc ctgatcgact acaaccgcgc ggggtccgcc ctgatggaaa tcgtttccga
     8581 gccggacatc gacaccccgg aagaagccta cgcctacctc aagtctctcc agcagattct
     8641 gaattacggg gatatctccg acgcggacat ggaaaagggc cagatgcggt gcgatgtgaa
     8701 tatttccctg cgtccccacg ggcagaagga attgggcgcc aaggtggaaa tgaagaacat
     8761 caactccatg tccgccgtcc gcagagccct tcattatgaa atccagcgcc aggcggaaga
     8821 actggacatg ggcattcctc aaatccagtc cacccgccgc tgggacgacg aacgcggaga
     8881 aagcgtcgtc atgcgaacca aggaagacgc gcacgattac cgttatttcc cctgtccgga
     8941 tctagttccc gtacgcacgg ccccgctggt ggagaaagtg cgcgggcaga ttcccgaact
     9001 gcctcaggaa cggcagaaac gcttcatgga aggatacggc ctgagcgagt acgacgccaa
     9061 cgtgctggtg ggagacctgg aactggcacg cttttttgaa gaggcggcgc ggggaaccgc
     9121 cagcggcaaa aaaatcgcca actgggtgat taacaacatt tccgccgtgc tgaatgaaaa
     9181 aggcatgcgc ccgtctgaat gcccggtgaa acccggtgcc atccgggagc tgatcgccat
     9241 tattgacgac ggcaccgttt ccaacaacca ggccaaggac gtattcgcca aaatgtggga
     9301 tgaaccggcc ctcgccgcag cgcaggccgc caagctgctg ggctttgaaa aggcggattc
     9361 ctcttttctg gacggcatcg tgcgggaagt catttccgcc aatccggaca aggtggcgga
     9421 aatacagggg ggcaatgaaa agctcctgaa ctggcttacc ggccaggtca tgaaggccgc
     9481 caaaggcaaa gccaacccga aaatcgtgac ggaagcgctg aaaaaagccc tttccatgga
     9541 gtaaccataa acaaagagcc gcttcccttg ccggtgccgg ctccttgccc gcagggcatc
     9601 acggtttgaa cagcttcctg tttccggcca gggtgttcca tacctgcttc acttccccgg
     9661 ccagcgtctg cttcatcatg gcaagggaaa agtccgccgc ctggcccata ctgatgtagg
     9721 gaggcagggc aagggcgtcc ctgtccacat gcgcgtccag cagagcggcg cccggataat
     9781 tcaggaacat gtccaccatc tggtccacct ggctggattt gtccaataaa aaccccttga
     9841 tgccgacggc atccgccacg gcggcaaaag aggggttgtt caggttgatc tgccacggaa
     9901 tcagcccggc cgcctgcatt tccaattgga tgaaatccag acagtcattg ttatacacca
     9961 cgattttcac cggcagcctg tactggacaa tcgtgatgag atcccccagc agcatggaca
    10021 ggccgccatc tccacacagg gcaattacct gccgttcggg gtattccatc tgcgccccaa
    10081 tagccattgg catggcattg gccatggagc catgattgaa ggaagccagc gtcctcctgc
    10141 ccggcgtggc gcacaggaac ctggcgctcc agatgcaggg ggtgccggta tctaccgtaa
    10201 atacggcgtc ggaagccgca tgcctgttca gggcggtcgt gagctgttcc ggccggatgg
    10261 gagactcctt gtcatttcct tccatatagg cgttcatctc cttcacgtcc ctggcgtggc
    10321 gtttcagggc ggcgtccaaa tgcccggaat ccgtcttttc ctgcaccatg ttcagcagag
    10381 cttccgccgt gacggaaaca tccccgcaaa tacccaggtc caggcggcag cggcggccca
    10441 gcacttcacc gcgcctgtca atctgcacga tttcaggttt ggtgggaatg aaattgaaat
    10501 aggggaaatc cgtcccccac aacacgagca tgtcgctttc atgcatggcc ttgtaggcat
    10561 ctccccatcc aagcagcccc gtcatgccga tgcccagggg attgtcatgt tcaaaataat
    10621 cctttcccct ccatgtgtag gcaatcggag ctttcaggcg gtgcgcgagc cggacgaccc
    10681 tgtcttccgc tcccgcgcag ccggcgccgc agaagaaagt aatgcggcgg tggtcgtcaa
    10741 gcatccgtgc cagaagggat acggattcat gctcaggaac aacattctcc cgcgtgtagg
    10801 aaggaggatg caccagattc ttcatctccg caggggcgtc cgcaatgtct ccgggcaaga
    10861 cgacgacacc tacgtcgcgc ctggcccacg cgtgctgaat ggcggacatc aaaatggacg
    10921 gggcctggga agcttccgaa accagttccg catatgcact gcattcctta aaaagctgtt
    10981 ccggatgcgt ggcctggaaa tattccatgc ctacctggct ctgcgggatg tgggaagcaa
    11041 tggccagcac cggggcatgg ttccggtggg cgtcaaacag gccgttgatc aaatggaggt
    11101 tcccggggcc gctgctgccg cagcatacag ccagattccc gctcagctgg gcttccgcgc
    11161 tcgcggcaaa agccgccact tcctcatgcc gtacatgaat ccattcaata gtcttcctcc
    11221 tcctcaaagc gtccgtaacg gggttcaggc tatcccccac aatgccgtaa atccgcttaa
    11281 ctcccgcctt ctccaaaatt tcaacaatct gatcggctac cctgtgcatg cagattagac
    11341 accagccaac ctccaacgga ttcattctta tgtgtcatcc cctccatctt ttccgcaccg
    11401 gaaaaaatgc ctgaggattt cccctgatat cataaggccg ccgccttttc aggcagcggc
    11461 ctatgaattt accagttctc tggtggaaaa ccgtcaggaa cggcggcggc gcatcatcag
    11521 aacggccagg cccaggattc ccagagaagc cgaggccggt tccggaacct gaaggccggc
    11581 aaaaccggca atctgttccg cggaaagttt tgtatccgtc cactgaattt caccccatgt
    11641 aagattggga ttaatccagc tttggatatc agtgcgattt ccgttcatgt tgccgttgta
    11701 ggacaacgtg tcaaacaagg aaccattcac atagacctcc acagactggc tttggtttgc
    11761 gccggtaacg gccaaagtca cgttaagaag acctccctcc aaaacaacgg gagtttcaga
    11821 aacgtctcca cggttttggg aaaaagagcc ggtagaagta ttc
//
