LOCUS       c00046_gnlPro..        18638 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|BNHILMBH_46.
ACCESSION   c00046_gnlPro..
VERSION     c00046_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-05 13:59:16
            Original ID  :: gnl|Prokka|BNHILMBH_46
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 18638
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..18638
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[5574:8638]"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      5575..8638
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
     cand_cluster    1..18638
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /kind="single"
                     /product="Pyruvate2acetate-formate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..18638
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Pyruvate2acetate-formate"
                     /region_number="1"
                     /rules="((PFL_acetate1 or PFL_acetate2) and Radical_SAM)"
                     /tool="gutsmash"
     CDS             complement(3..407)
                     /locus_tag="ctg46_1"
                     /transl_table=11
                     /translation="VCSLSEALYFFPRGGLDGKWFAVTNDGKLEEDWKDPEKRKNLKKL
                     GGIMRTPVFVNKGRRVIVPFHNMGSGTKFHISDDGGLTWHVSRNGVTSPKHEARPPHQG
                     VRWFNNAVEATVLEMKDGSLWALVRTSLDQA"
     CDS             complement(501..674)
                     /locus_tag="ctg46_2"
                     /transl_table=11
                     /translation="MPNRRQHPFRSLKLSPLRRLMRGAASSVWTPVKYAIIPVPARDRI
                     TWSAGITEKHGK"
     CDS             complement(808..1596)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Lipase_GDSL_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg46_3"
                     /sec_met_domain="Lipase_GDSL_2 (E-value: 4.7e-24, bitscore:
                     75.9, seeds: 1564, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNFFSYMLAILLGGASVAFSAPSIPPSALPATLKPEPHQRDPYDW
                     NARHEAVKKRNRTVKPEYVMIGDSITHHWGGEPSGDGKNTGAGSWEKLFRPHTATNMGF
                     GFDYVDNAYYRVQNGELDGISPRVIIVLLGTNNLGHRKDTPQACADNIRAFVRLVRRKC
                     PSSKILLLGVLPRKEKNLAEPVKQTNRLLAELHNGKNIFFADPGKALLSADGASPQNEF
                     MKDVVHPNARGYEVLEKELAVLLKKLDAKYRGGKQAGKHS"
     CDS             complement(1645..1824)
                     /locus_tag="ctg46_4"
                     /transl_table=11
                     /translation="MSFLVKALPSVGESSFPGATGLSEQERPDAVFAWPLLRRDLPDGQ
                     WSFLLCRQKWRLRS"
     CDS             2901..3410
                     /locus_tag="ctg46_5"
                     /transl_table=11
                     /translation="LQWGTKIRGTIIRYLKVKRKIFCIGPRIFIKERKRNHRLTKRGKI
                     LGLHNALTIHECVQQSNKSCPLAWKILNIQHLKSSKSRCSQCHLDIGLITSRGPDTRSL
                     VKSISLFSHSSFLKALFKDFKIPRFKNARVFGYFPEIRVNLKLSRFMADHGKRTIPDRF
                     FVAGPR"
     CDS             3565..3753
                     /locus_tag="ctg46_6"
                     /transl_table=11
                     /translation="LLEPNEYRTSGRTLRYESTIVLMAGSVPGSSLPKANMTNEGWEAY
                     ASRIALPSRKKKSITFF"
     CDS             3750..3848
                     /locus_tag="ctg46_7"
                     /transl_table=11
                     /translation="LRFMNGTPEWYFRLKIHSKFIRSFKCSFRGSP"
     CDS             4158..4424
                     /locus_tag="ctg46_8"
                     /transl_table=11
                     /translation="LVSEFKRNLNDFSLHFSLISVILQSRLQCNTSRFRLITVANSQAN
                     GNGFFFWFRNQLNRFNEGIRNGLKEYFSQHSIPIRLGMLGKSV"
     CDS             5335..5460
                     /locus_tag="ctg46_9"
                     /transl_table=11
                     /translation="MKKDAPLQDSSEGPILFFHKKYTYLRNEPEKVKNSSLSQKN"
     CDS             5575..7842
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: PFL_acetate2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Gly_radical"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg46_10"
                     /sec_met_domain="Gly_radical (E-value: 7.6e-46, bitscore:
                     145.3, seeds: 99, tool: rule-based-clusters)"
                     /sec_met_domain="PFL_acetate2 (E-value: 3.9e-282, bitscore:
                     927.1, seeds: 33, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MISIVKDLKESTALPKEWQGFKPGAWTESIDVRDFIQHNYTPYSG
                     NEEFLSGPSQRTLRLWDELKVLLKREIDNGGVLDADEEVVSSITSHKPGYIDKELEVVV
                     GLQTDAPLKRALMPFGGLRMAQQALESYGFKMCEKTADIFKKIRKTHNEGVFDAYTSDI
                     RAARSAGIITGLPDAYGRGRIIGDYRRVALYGTDRLIAERRKDLKNREHSPLTDELIRL
                     REEMSEQIRALEELAQLGASYGCDLTRPAANAREAVQWTYLGYLAAVKEQNGAAMSLGR
                     VSTFFDIYFTRDLEQGLITEEEVQEIIDQFVMKLRIVRFIRTPDYNNLFSGDPTWVTES
                     IGGMGEDGRTLVTRSSFRMLQTLYNLGPAPEPNLTVLWSRNLPEAFKSFCAKVSIETSS
                     VQYENDDLMRPHWGDDYGIACCVSAMRIGKQMQFFGARANLAKCLLYALNGGVDELKGK
                     QVAPPSPRYTEEILNYDEVMALYDKMQDWLAKTYIDALNIIHYMHDKYCYERIEMALHD
                     PEILRTMATGIAGLSVAADSLSAIKYATVKAIRNEEGLIVDFKTEGEFPCYGNNDPRVD
                     DIACSLVSNFMEKLRKLHTYRNSLPTQSILTITSNVVYGKKTGNTPDGRRAGEPFAPGA
                     NPMHGRDRNGAVASMLSVAKLSYDDSLDGISYTFSIVPQALGKEERERRVKLVSLLDAY
                     FAATGHHINVNVLERETLLDAMDHPEKYPQLTIRVSGYAVNFIKLTREQQQEVINRTFH
                     TR"
     CDS             7928..8638
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: Radical_SAM"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg46_11"
                     /sec_met_domain="Radical_SAM (E-value: 1.2e-30, bitscore:
                     97.3, seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VESCGTVDGPGIRFVLFLSGCSLRCRYCHNPDTSYVRRGRLRSAG
                     DVLREIARYRDFLQAAGGGVTLSGGDPLFQPDFTGAVLKGCRELGLHTCLDTSGHLGVN
                     AGEEMLADTDLVLLDIKAWNPERYRSLTGGELRPTLEFAERLASLRKPVWLRYVLVPGV
                     TDNLEEIEGLSRHAALLGNVERVDVLPFHQMGRFKWDELKLDYTLKGTPEASAKLAEQV
                     RGIFRREGFPDCVH"
     CDS             complement(8739..10664)
                     /locus_tag="ctg46_12"
                     /transl_table=11
                     /translation="MTDSSSPDSSPASRNTFAHHLGMKGFLLMEGLLKLVGMKTLYRLG
                     RAAGAVAWYLLPQRRNIVERNLRIVLNPALRGKELQKLSRENFKRTIANFLCSAKTATL
                     TDEQLKHCVTVGGHEQFAAPVLEGRGQVCAIAHSGNWEALARIRAFYPEVERYGSMYRQ
                     FDNPLMEEYVYQRRTERGTQMFSKEGGIKAPMKMLKEGGALGVLSDQFVWEGVYVPFFG
                     KVTGTTPLPALLRKRAGADMVAIAVRTDAPGHWIADMGNVVDFSGSDGSLAGDTIEVNR
                     GLETLIRESVLDVFWMHHRWKSVDRFAPQDKKTAALLENMELKPYRILVAVPGALDEAL
                     ATVPLIRALKTVRCDMQVNVICPSAQMGIWKTVPEVTHVLPHDSLKQLREALVADEFYN
                     DGPLDMGVMLDGDMETLKALEPYGPMMFSGLDTHPGVRKYKFRVKAPVLRAAPPAHRVQ
                     LYLQLGGLHGLDVGKPSLFPVKKAAPAEGAPILIAPFSRLGSASEWSREQWTELVSLLP
                     GRTVLVALEEDRERAAALAEHLNVELAVGAPEALFSVMDGASVAVAVDGDFPSLCSFRG
                     LPVVTLFSTRLPDVYRPMGTFNRSLYSHQCCSPCFRKDCDRDVPCNRHIAVREVLDALR
                     EISGKE"
     CDS             11203..12366
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_1"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg46_13"
                     /sec_met_domain="Abhydrolase_1 (E-value: 2.1e-30, bitscore:
                     96.3, seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQLPAVQTKFLNLPNSFSLRNGATLDKVCVAYEQYGTLTPEKDNA
                     ILLFHALSGSQHAYGYNPEVPGTGSLWKPENHEGWWNSIIGPGKPLDTDRFCIICANYL
                     GGCYGTTGPATPCPADGQPYGSRFPHVEIADQARLQALLLDSLGIERVHLMGPSVGGLI
                     ALSFACQFPERVRSFISIGSGYRASIEHRLSLFEQILAIELDPDFQGGDYYRGPAPKKG
                     LAFARIIGHKSFVYQEGLEQRARKEVGGNYGLLTWMTPTRSTQSYMLHQGTKFAERFDA
                     NSYIRIADMWAEFDIRDHTPDGTFQTALEGFRRAGIPALIFSIDTDCCFRPAEQQDFAA
                     QLEAAHIPTEFHTIASTKGHDSFLLEPELYAEPIRRILAARKPKGTA"
     CDS             complement(12505..12609)
                     /locus_tag="ctg46_14"
                     /transl_table=11
                     /translation="LSDVFRFGGVIMISHEDVTAKTLFGFIRLRLLSR"
     CDS             complement(12579..12995)
                     /locus_tag="ctg46_15"
                     /transl_table=11
                     /translation="LTSLMAVYFHSHSMGVSRSGRSAWRTGQDKAVFSSMARRGWLPSR
                     GMIAFSSIFSIPLDDSAARARTRMPFKSTPFLAATTETRLIMQEASVEPSKTPGEGNSA
                     RPSKEAGRSVANVTLEGIKVVSQRNCPTFSVSEV"
ORIGIN
        1 cacgcctggt ccagggaagt acggacaagc gcccacaacg aaccgtcctt catctccaaa
       61 accgtggctt ccacggcatt gttgaaccat ctgacaccct ggtggggggg cctggcttca
      121 tgtttggggg aagtaacacc gttcctggat acatgccagg tcagtccccc gtcatcggaa
      181 atatgaaact tggtaccgct gcccatgttg tggaacggaa caatcaccct gcggcccttg
      241 ttcacaaaaa caggggtgcg catgatgccg cccagttttt tcagattttt cctcttttcc
      301 ggatctttcc agtcttcttc cagcttgccg tcattcgtga cggcaaacca cttgccgtcc
      361 agcccccccc ttggaaagaa atacaaagcc tccgataggc tgcacacgaa tgaattccct
      421 ggtcaggggg ttgcgcacaa tagccggaga ttccttggga atgccgccgt agttgggagg
      481 gtagccagcc ggagcggcct tcatttccca tgtttttccg ttatccctgc tgaccaggta
      541 atccggtccc ttgcgggtac cggaataatg gcgtatttca cgggagtcca cacggatgag
      601 gccgcgcccc gcatcagccg gcggagtggc gacaacttca ggctccggaa cgggtgctgc
      661 cttctgttgg gcataacagc aacaaaagga accggtcaac aatgcaaaca acaggttttt
      721 cataaactaa atatcaaatg ccgtatattt tcctcagccg gggctttccc ttcaagcaaa
      781 atcctgcctt ccatcagaag acgatcatca ggaatgcttt cccgcctgct tccctccccg
      841 gtattttgca tcaagctttt tcaaaagtac ggccagttcc ttttccaaaa cctcatatcc
      901 cctggcattg ggatgcacca catccttcat aaattcattc tgaggagaag caccgtctgc
      961 ggaaagaaga gcctttcccg gatcggcaaa gaaaatgttc tttccgttat gcagctccgc
     1021 cagcagcctg ttcgtctgct tcaccggttc cgccaggttt ttctccttcc ttggaagaac
     1081 gcccagcaac agaattttgg aagaggggca tttccggcgc accaggcgga caaacgccct
     1141 gatattgtcc gcacatgcct gcggcgtatc cttgcggtgc cccagattat tggttcccag
     1201 cagcacgatg atgacccgcg gagaaatgcc gtccagctcc ccgttttgca cacggtaata
     1261 ggcattatcc acataatcaa atccaaagcc catattcgtc gcagtatgcg gacggaataa
     1321 tttctcccag gaacccgctc ccgtgttttt tccgtccccg gaaggctccc ctccccagtg
     1381 gtgggtaatg ctgtccccta tcatcacata ttcaggcttg acggtccggt ttcttttttt
     1441 aacggcttca tgccgggcat tccaatcata cggatcccgc tgatggggct ccggcttcag
     1501 ggttgcgggc aacgcggagg gagggatgga aggtgcggaa aacgccacac tggccccccc
     1561 cagcaatatg gcgagcatgt aggagaagaa attcatgata aaaaagtgaa accggtttcc
     1621 agtttaagca aatcctgccg tgcatcaaga tcgcaggcgc cacttttgcc ggcagagtaa
     1681 aaaagaccac tgcccgtccg gcaaatcccg ccgcaacagc ggccaggcga acaccgcatc
     1741 cggcctttcc tgttccgaga gccctgttgc cccaggaaag ctcgactccc caacggaggg
     1801 taatgctttc accaaaaacg acataccccc gtttgacggt ccgggtccgt tccatcactg
     1861 cctcatggcg tttttccagt catgcacggc ccgctggttc tcctggggtt tcagcatagg
     1921 aagcagttct ccagcacagg caccggagaa aaagacgaca caaaaaactc ccgccagcaa
     1981 taaacaaaag catacatgag gtttccggta atcgctaaga tactgcaata gaaattcggc
     2041 aagtaaaagg aaaagagatc caattatttg taatccgtta cgttgtcgac atttttgata
     2101 ttcggcgaaa gggtattgcc tgagaacaac gccttgaact cttccgggga acatatcatc
     2161 ttcgggttaa aatctctgga ctgcacataa ctcaccaaag acgaatacaa ttgcctcccc
     2221 tctggagtct tacgaagggc ttcaggatca gccatgcaaa caagcaattt accttttccg
     2281 atccccatct caaatatgag gcccaatttg tgattcctct ccatattatc cactacttga
     2341 acaataggat ttaagtcgga aggcgccaaa tccaaaatta gaggacgtga tgacttgatc
     2401 acgctccacc actgccagtt cgtctgcgca tccgtgggga aatttttgaa aagcggatgc
     2461 tctggatcca tcagtagaga aagggttcca ggagaaacgg gtctgcgaag cgactctgaa
     2521 atacctttaa acatcgcaaa attccaataa tcaggtgtca ccaaaccacc aactgaccgc
     2581 agcgcgatgt cctgatgatt gggaaaccag agcatggaag ccccctcatt caactgcctg
     2641 agcgttttac ctgtcagctt gcggggagct aagaaggcaa ccgggagttc ttgcggttct
     2701 tgatccggat aaatccaaaa atcatatgtg ttcacgctat ccttaccttt catccaaaga
     2761 accagtttca aacgatccgg caccttgatc ccggacagag gaatgctgat ttttgacgtc
     2821 tcacttaatt ctccctgtct gccatggagc atcttgctac ctttgtgcaa cactttgccg
     2881 gaggaatcct caagcctcca ttgcaatggg gcacaaagat cagaggaacc ataattcgct
     2941 acctgaaggt caaaagaaag attttctgta ttggtccacg tatatttatc aaagagcgca
     3001 agaggaacca ccgcctgaca aaaagaggaa aaatccttgg cctccataat gcccttacta
     3061 tccatgaatg cgtccaacag tccaacaaga gctgtcccct ggcctggaaa atcctgaata
     3121 tccagcattt gaaatcctcc aaatcccggt gttctcaatg ccatctcgat atcggcctta
     3181 taacatcgcg cggcccagac accagaagct tggtgaaaag catcagcttg ttttcccatt
     3241 cctcgttcct gaaggcgctt tttaaagatt tcaagattcc acggtttaag aacgcccgtg
     3301 tatttggata tttccctgaa atccgggtaa atttgaaact gtcccgtttc atggccgatc
     3361 acgggaagcg gacaatccct gatcgctttt tcgtagctgg tcctcgttga cggaagacag
     3421 gcgttgagta ttcctccatc ccgggcatct gcaaaagcga acgaggaacg gacgtgattg
     3481 tcatatccag aatgacgatc agccccaaca cgacatgtcg tcaagaaatc ctcgcctttc
     3541 ttccaccctt ccctgcccag atagttgttg gaaccaaacg agtacaggac gtcgggccgc
     3601 actttgcggt atgaatccac aatagttctc atggccggat ctgtcccggg aagttcattg
     3661 cccaaggcga acatgacaaa tgaaggatgg gaggcatacg cctccagaat agccctaccc
     3721 tcacggaaaa agaaatccat cacgttcttt tgagattcat gaatggcacc ccagaatggt
     3781 atttcaggct gaagatacat tccaagttca tccgcagctt caaatgcagc ttccggggga
     3841 gtccatgaat ggaatcttac ataattgaat ccataggccg ccgctatacc aagatggcgg
     3901 agccatgcct ttttatccat gggagggtat ccagtcaggg gaaaaacgca ggcatcatgc
     3961 cgacctctta aaaaaatctt cttcccattg attgtaaaat tagttccctg aacagcaaaa
     4021 cagcgcattc cgaagacttt actggttgtg tcgacttttc ctgccaattc cagtttgatg
     4081 tgcattttgt ataaattcgg agagaattcg ctccagagct ccggctcttc tcccatgggg
     4141 taattcaatt tcacatgttg gtctccgagt ttaagaggaa cctcaatgac ttttctctcc
     4201 acttttccct tatttccgtt attctgcaaa gccgcctcca atgtaatacg agccgtttcc
     4261 ggcttataac tgttgcgaat agtcaggcaa acggtaacgg attttttttc tggttcagga
     4321 accagcttaa ccgattcaac gaagggatca gaaacggcct caaggaatat ttttcccaac
     4381 attccattcc aattcgtctg ggtatgctcg gtaaaagcgt gtgaattgaa aacgcctgcc
     4441 ggataatgcc tgcggctgtt gtccacagag attgtcaatg tatgtttccc cggaaaaaga
     4501 aattccgtca gatcataacg atggggtgtt tgaacattat cacaggaacc gattttttta
     4561 ccatctacga aaacggttgt ctttttcgtc cgttccacat gcaaaaataa ccgtttacct
     4621 ttgaacgttt ccggaacatt cacttccttt ctgtacaagg cctctccttc gtaagtaacg
     4681 gcgcgggaaa gatgttttgt ctcctgacgg ttattattga cattcccctt gccccattca
     4741 tccatggttc caggtagtac aacagcaact ttttcctgtt tgaatggaag ggaaagttcc
     4801 cataacccat ccaggggtag caattctcgt cccatcgctg ggaaaatagt cccccaaagc
     4861 aggaaatata cagacatcat ccgaataagc cataaaacat cggaacaata attggaaaag
     4921 aagtatcttg attttgtttt cattataaga atttgcattt gagaaaccgt acggctcagt
     4981 cattcgacca cttgcacatt ggaaatacgc ccttgtcacc attgatttga gagctcccta
     5041 aaacatttgg ttagtaatac gaagaactcc ttccatttta tcaaacaacc tgaataccgt
     5101 gacaacgaaa ggcaaaaaag catggattct taccgccgac atgggaaaca accacacctc
     5161 tttgaatacg ttttgccgaa aactgtcaga agagcttctg acagatattt tcacaaaggt
     5221 attcattgat agctctaccg gaaaaacaat tgattggtac ttcatcggca actcatttct
     5281 ttgctttttt cttttatatc ttttcctatt tttctcgttt tcagatgagc tcccatgaaa
     5341 aaagatgccc ccctacaaga ctcttcagaa ggccccattc tgtttttcca taaaaaatat
     5401 acatatctcc gaaatgaacc agaaaaggta aagaacagtt ccctctccca gaagaattag
     5461 ccttgttgtc tcccggaatt cacgatataa ttacgtggcg cggagttttg ccgtttccgg
     5521 cctttcaacg gctgcggaac gtttttctcc ggtcttcttc actacatcct atttatgatc
     5581 agcatagtaa aagacttgaa ggagtccacc gcccttccga aggaatggca gggattcaag
     5641 ccgggagcat ggacggagtc cattgacgta cgggatttca tccagcataa ctacacgccc
     5701 tattccggca atgaagaatt tctttccggc ccctcccagc gcacgctccg tttatgggat
     5761 gaactgaaag tcctgctgaa aagggaaata gacaacggcg gcgttctgga tgctgatgaa
     5821 gaagtggtat cctccatcac ctcccacaag cccggctaca ttgacaagga actggaagtg
     5881 gtcgtaggcc tccagacaga cgcccccctg aaacgggccc tgatgccctt tggcggcctg
     5941 cgcatggccc agcaggccct ggaatcctac gggttcaaga tgtgcgagaa aaccgcggat
     6001 attttcaaaa agatacgcaa gacgcacaat gaaggcgttt tcgacgccta cacttccgat
     6061 atccgggcgg cccgttccgc cggcattatt accggccttc cggacgccta tggccgcggc
     6121 cgcatcatcg gggactaccg ccgggtggcc ctgtacggca cggacagact gattgccgaa
     6181 cgccgcaagg acctcaaaaa ccgtgaacat tcccccctta cggatgagct gatccgcctg
     6241 cgcgaagaaa tgagcgaaca aatacgcgcc ctggaagaac tcgcccagct gggcgcctcc
     6301 tacggctgcg acctcactcg ccccgccgca aacgcccgcg aagccgtgca atggacgtac
     6361 ctgggctacc tagccgccgt gaaggaacag aacggagcgg ccatgtccct gggccgcgtt
     6421 tccactttct tcgacattta tttcacccgc gacctggaac aggggctcat cacggaagag
     6481 gaagttcagg aaatcatcga ccagttcgtg atgaagctgc gcatcgtccg tttcatccgc
     6541 acgcctgatt acaataacct gttctccgga gaccccacct gggtgacgga atccatcggc
     6601 ggcatgggag aggacgggcg caccctcgtc acccgcagtt ccttccgcat gctgcagacc
     6661 ctgtacaacc tggggccggc tccggaaccg aacctgaccg ttctgtggtc ccggaacctg
     6721 ccggaagcct tcaaaagctt ctgcgccaag gtttccattg aaacgtcctc cgtccaatac
     6781 gagaacgacg acctgatgcg cccgcactgg ggcgacgact acggcatcgc atgctgcgtg
     6841 tccgccatgc gcatcggcaa gcagatgcag ttcttcggag cgcgcgccaa cctcgccaag
     6901 tgccttctct acgccctgaa cggcggcgtg gatgaactca agggcaaaca ggtggccccg
     6961 ccctcccccc gctacacgga agaaattctc aactatgatg aagtgatggc cctgtacgac
     7021 aagatgcagg actggctcgc caaaacttac attgacgcgc tgaacatcat ccactacatg
     7081 cacgacaaat actgctatga acgcattgaa atggcgctgc atgatccgga aatcctgcgc
     7141 acgatggcca cgggaatcgc cgggctttcc gtggcggcgg actccctgtc cgccatcaag
     7201 tacgccaccg taaaagccat ccgcaatgaa gaggggctga ttgtggactt caagacggaa
     7261 ggggaattcc cctgttacgg gaacaatgac ccgcgcgtgg acgacatagc atgcagcctg
     7321 gtcagcaatt tcatggaaaa actgcgcaag ctccacactt accgcaattc cctgcccacc
     7381 cagtccatcc tgacgatcac ctccaacgtg gtgtacggca aaaagacggg caacacgccg
     7441 gacggccgcc gagccgggga accgttcgcc cccggcgcca accccatgca cggaagggac
     7501 aggaacggag ccgtggcgtc catgctctcc gtagccaagc tgtcctatga cgactccctg
     7561 gacggcatct cctacacctt ctccatcgtt ccgcaggccc tgggcaagga ggaaagggaa
     7621 cgccgcgtca agctcgtctc cctgctggac gcctactttg ccgctacagg tcaccacatt
     7681 aatgtgaacg tactggaacg ggaaacgctt ctcgacgcca tggatcaccc ggaaaaatac
     7741 ccgcagctta ccatccgcgt ttccggctat gccgtgaatt tcatcaagct gacccgggaa
     7801 cagcagcagg aggtcatcaa ccgcaccttc cacacccgct aacccggacg acacacggat
     7861 gccgcaggtt tttccacaaa accatgatcc ggacggagaa agctccgtca ccggtttggt
     7921 tcattccgtg gaatcctgcg gcaccgtgga cggtcccggc atccgctttg tccttttcct
     7981 gtccggctgc agcctgcgct gccgctactg ccacaatccg gatacctcct acgttcggcg
     8041 gggccggctc agaagcgcgg gtgatgtcct cagggaaata gcccgttacc gggatttttt
     8101 gcaggcggcg ggcggcggcg tcaccctctc cggcggggac cccctcttcc aacctgattt
     8161 taccggcgcc gtgctgaaag gctgccggga actgggactg catacctgcc tggacacctc
     8221 cggccatctg ggcgtgaatg cgggcgaaga aatgctggcg gatacggacc tggtcctgct
     8281 ggatatcaag gcatggaatc cggaacggta ccgctccctg acaggcgggg aactgcgccc
     8341 tacgctggag tttgcggaac gcctggcctc cctccgcaag cccgtgtggc tgaggtatgt
     8401 gctggtaccc ggcgttacgg ataatctgga agaaattgag ggactctccc gccatgcggc
     8461 gctcctgggc aacgtggaac gcgtggacgt gctccctttc caccagatgg ggagattcaa
     8521 atgggatgaa ttgaagctgg attatacctt gaagggcacc ccggaagcgt ccgcaaaact
     8581 ggcggaacag gtccgcggca ttttccggcg ggaaggcttt ccggattgcg tgcattaacc
     8641 ggattttcgc gccttggcgc catcaaccgc agcaaaccga atacagatat ctcccctcct
     8701 catcttccgg atgaaaggcc cttctcccct ttcccaaatt attcctttcc ggaaatttcc
     8761 cgcaaagcat ccagcacttc ccgcacggca atgtggcggt tgcaggggac atcccggtca
     8821 caatccttcc ggaagcaggg ggaacagcac tggtggctgt aaagggaacg gttgaatgta
     8881 cccatagggc ggtacacatc cggaagccgg gtggaaaaca gagtcaccac cggaagcccg
     8941 cggaaggaac agagggacgg gaaatcgcca tccacggcta ccgccaccga agcgccgtcc
     9001 atgacggaaa acagagcctc cggcgcaccc acagccagtt ccacattcaa atgttccgcc
     9061 agcgcggcgg cgcgctcccg gtcttcttcc agagccacca gaaccgtccg tcccggcaaa
     9121 agggaaacca gttccgtcca ctgctcccgg ctccattcac tggcgcttcc cagacgggaa
     9181 aacggagcaa ttaaaatggg ggcgccttcc gccggggccg cttttttcac agggaacaaa
     9241 gacggtttac cgacgtccag cccatgcagc ccccccaatt gcagataaag ctgcacccgg
     9301 tgcgccgggg gggcggcgcg caggacgggg gcctttaccc ggaatttgta tttccggacg
     9361 ccgggatgcg tgtccagccc ggagaacatc atggggccat acggttccag cgctttcagg
     9421 gtttccatat ctccatccag catgacgccc atatccagcg ggccgtcatt gtaaaattca
     9481 tctgccacca aagcttcccg aagctgcttc agggaatcgt gcggcagcac atgggtaacc
     9541 tccggcaccg tcttccatat tcccatctgg gcagacgggc agataacgtt cacctgcatg
     9601 tcgcaccgga cggttttcag ggcacgaatc aggggaacgg tcgccagggc ttcatccaac
     9661 gccccgggaa cggctacaag aatgcggtac ggcttcagct ccatattttc cagaagcgca
     9721 gccgtttttt tatcctgcgg agcaaaacgg tcaacggatt tccagcggtg gtgcatccag
     9781 aacacatcca gcacggattc ccggatcaat gtttccagcc ccctgttcac ttcaatagta
     9841 tcccccgcca gagagccgtc cgacccggaa aaatccacca cattccccat atccgctatc
     9901 cagtggccgg gagcatccgt acgcaccgct atggccacca tgtccgcgcc agcccttttt
     9961 cgcagcagag cgggcagcgg agtcgtgccg gtcaccttgc cgaaaaaggg gacatacacc
    10021 ccctcccata cgaactggtc gctcagcacg cccagggccc ccccttcctt gagcattttc
    10081 atgggagcct tgatgccgcc ctccttggag aacatctgag ttccacgttc cgtgcgccgc
    10141 tggtacacgt attcctccat cagcggattg tcaaactggc ggtacatgga cccgtaacgc
    10201 tccacctccg ggtaaaatgc gcgtattctc gccagcgcct cccagttgcc ggagtgggct
    10261 atggcgcaaa cctgcccgcg cccttccagc acaggcgcgg caaactgttc gtgccctccg
    10321 accgtcacgc aatgcttcaa ctgctcatcc gtcagggtgg ccgtcttcgc ggaacacagg
    10381 aaattggcaa tggtcctttt gaaattttcc cggcttaatt tctgcagttc ctttccgcgc
    10441 agggccggat tcaaaacgat gcgcagattc ctttccacaa tgttccggcg ctggggaagc
    10501 agataccacg ccacggcccc tgccgcgcgc cccagccggt acagcgtttt catgcccacg
    10561 agcttcaaca gcccttccat gagcagaaac cctttcattc ccaaatgatg ggcaaacgta
    10621 ttccgggaag ccggggagga atcaggagag gaagaatcag tcataaggaa aaccggaaaa
    10681 gatgttatac gaatcccctc cggtccacaa accctttatt cccccggctg aggtcccttc
    10741 ccgcatttta ttttctcgga taaatgacgt cttccctaaa tttttccgcc ggcgcggaat
    10801 ccaaagccat cccatgcttt actgcatctt cctcataaaa gcatctctgc ggagacggca
    10861 tcttactttt ggcaaagaaa tgactttaca attcttaact aaacggtata ttccgtctcc
    10921 cgaaccgaac accaaaccgg agttatacac catgaaagtt ctttcttcct tagcctctat
    10981 gaagcgccgc cacgcagact gccaaatcgt gaagcgcaag ggcacgctgt atgtgatctg
    11041 caagagcaat cccaagttca aggcccgcca gggcgctacg gcaggcacgc gcctttccaa
    11101 aaagggcgtc aagtaatccc tggcccagca cagatttcaa gaagaccgcc gcccgccggg
    11161 tgccggtctt tttttgctga ccaagccctt ttccgtacat ccatgcagct tcctgccgtc
    11221 caaaccaaat tcctgaatct tcccaactcc ttctccctga ggaatggagc tacgcttgac
    11281 aaggtatgcg tcgcctatga acagtacgga accctgacgc cggaaaaaga caacgccatc
    11341 ctgctgttcc atgccctttc cggcagccag cacgcctatg gctacaatcc ggaagtcccg
    11401 ggcaccggct ccctctggaa accggaaaac cacgaaggct ggtggaacag catcatcggc
    11461 cccggcaagc cgctggacac ggaccgcttc tgtatcatct gcgccaatta cctgggaggg
    11521 tgctacggca ccacaggccc cgctaccccc tgccctgcgg acggccagcc ctacggctcc
    11581 cgcttccctc acgtggagat cgcagaccag gcacgcctcc aggcccttct gctggacagc
    11641 ctgggcatag aacgcgttca tcttatgggc ccctctgtgg gcggcctgat cgccctcagt
    11701 ttcgcgtgcc aattcccgga acgcgtccgg agcttcatct ccatcggctc cggttaccgg
    11761 gcttccattg aacaccgcct gtccctgttt gaacaaatcc tggccattga gcttgacccg
    11821 gatttccagg gcggggatta ttaccggggg ccggcgccca aaaaagggct ggcattcgcc
    11881 cgtatcatcg gccacaaatc atttgtttac caggaggggc tggaacagcg cgccagaaaa
    11941 gaggtgggag gcaactacgg cctgctcacg tggatgactc ccacccgcag cacgcaaagc
    12001 tacatgcttc accaggggac caagttcgcg gaacgttttg acgccaactc ctatatccgc
    12061 attgcggata tgtgggcgga gttcgacatc cgcgaccaca ccccggacgg aacatttcaa
    12121 accgccctgg aaggcttccg ccgcgcaggg attcccgcgc ttatcttttc cattgataca
    12181 gactgctgtt tccgcccggc ggaacagcag gatttcgcgg cgcagcttga agccgcccat
    12241 attcccacgg agttccatac catcgcttcc accaagggac acgattcctt cctgctggag
    12301 ccggagcttt atgcggaacc catccggcgc attctggccg caaggaagcc gaaggggacg
    12361 gcgtaagctt ttttccgccg caagaagaca cggcggagca gcgcttaaaa agaaatgatg
    12421 ccgggaaccg gaagcgagag ggaaaaatca accatgtcat gaaggaacgg ccaggttcct
    12481 tgcaaagcgg aacttcacgg ctcttcaacg tgacaataac ctgagccgga tgaacccgaa
    12541 cagggttttc gctgtcacat cttcatgact gatcattatt acacctccga aacggaaaac
    12601 gtcggacaat tccgctgcga aaccaccttt atcccttcca acgttacgtt tgccacggac
    12661 ctgcccgctt cttttgaagg ccgcgcagaa ttcccctccc ccggagtttt gctcggttcc
    12721 acgctcgcct cctgcatgat gagcctggtt tccgtggtcg cggccagaaa aggagtggat
    12781 ttgaaaggca tgcgcgttct ggcgcgtgcg gcggaatcat ccaagggaat tgaaaaaatt
    12841 gaactgaagg caatcatgcc cctggaaggc agccaccctc tccgcgccat gctggaaaaa
    12901 accgccttgt cctgccctgt gcgccaggcg ctgcggcccg atctggaaac gcccattgaa
    12961 tgggaatgga agtaaacagc catcagggaa gtcaacccaa gcttgaagtt atccttaaag
    13021 aaatcccgtc cattcatgaa aaaagccgct gcggatgatt ccgcagcggc tttccaattg
    13081 gctgacgttt tttcctttag aagttgtagc ggtagccgat actcccgttg atggagctgg
    13141 aaccgctgcg gatatccgcg ttgccgtcca caaaaatgac gccctgagtg cccacgggaa
    13201 cgctcagccc cgcgccaatc tggaaggccg tgcttccgac cttggcgcca tacaccggac
    13261 gcgtatagga gggatccgcc aggaagccca cattggcctg cccgcggcgg tctcccatat
    13321 cctgggaaac gttcacccgt acttctccca gcgcttcacg cccgaagacg ttggacccca
    13381 tgagtccgga gagccgggcg cccacagcga cagcagccgt agtcagttcc tggtcttcca
    13441 ccttcagtcc ggcatttcct gcagaaccgc tttcccgata gccgtccata cgggtcgtca
    13501 cgatggaagc gttgaacaaa ggctggagaa tcacgctcct gtcttcattg agagcgatgt
    13561 catacgccaa ctcgtacatg gcgccgaaac cggctcccgt cgtattgccg cgggcctggt
    13621 aagaccccgt accgtaatcc accgtgcgcg tcagcgaggc atcattccag ccgcccgtca
    13681 gaatcagcag atgggaccat ttacggtact ggtagcgggc gaacagattg acatagtaac
    13741 tgtccaggtc tccgtccgcc gtatccgccg cgctggccgt caggcttccg taattggccg
    13801 taaacgcagc tcccgcagtg aagcggtcgt tgatatccac gtccatgcct accgtgcctc
    13861 cccaggtggt gagttcgtag ccgctttcat cccccctggt gtccagcttg gcataagacc
    13921 cggttccctg catccacata tggaagtagg gcatgtcttc atggacatat gcagggttaa
    13981 cgcccatctg cgccacgcgg ttgcgtatcc agcccatctg gtcgcgcagg gagtcgcgct
    14041 gggcgatgcc caggctggta accgtgctgc cggcggcggc ggccagtttg cgggcggcgc
    14101 cggaatagtc gcctgaattc tgggaaagaa gaacagaggt atagaaatcg cgcaaggcag
    14161 tgccttcttc catgtgatag cgggaattcc aaaggatgtc cgctccagtg gcggcattcc
    14221 gcgtcaggga agagtcacgg aaaatgtttt ccgtgcgcgc cgtaccggtg aggatgatgg
    14281 ccgtcatgct gttattggtg gtcagctcca ggttttcata catggaacca agaatcatat
    14341 cctggagggt gacattgtca cccagggaca caagcgcgcc gtccgttgtc ttgaacaatt
    14401 ccatattcag cgtttccgaa ctcccggaaa ccagggtatc cagattgttc atgaccagcg
    14461 tgacttcccc cgtcccgtct cccagcgtaa tatttccgct ggaggtgaca aagggattgc
    14521 ccaggccgtc caccgttgtg gaggaagtgg taatggccac cgtgctgtcc cccgtcacgc
    14581 tcaagccgtc cgagccaagc gtcagctggg ttttgggatc gtccgcgctg ccgatattga
    14641 gcgtgccgcc attcacggta atcccctgat aggaagcctg ggcgggattg ccgccctccc
    14701 ctgccgctcc ggccagggtc agcacgccgc cgtcactcac attcaggtga taacctgcat
    14761 tgcctgcacc cttgatagtc tggacgcttc cgttgccgga tttgacgttg agcgttccgg
    14821 atgccccgtc cagcgtaccg gtaaaggcat gggaagcgga agaattgatc gtcatttccg
    14881 caccgctcag cttcagagct ccgccgcccg ccagtccgga aacggtattc acggaaccgg
    14941 ttgcggcgga cagggcggac ccttcacgga tatccagcag gacaccgttc agggaagagc
    15001 cgttgcccag tgtcagggag gagtccgttc ccgtacctcc caaggtcagc gtaccgtccc
    15061 cggagataat cacctccgtg acatggctgc cggcctgctg gccggtaaga accatctggg
    15121 ttccgttacc caaattcagg gttccccctc ccgcgccggc agccagcgtc tccaccgtgg
    15181 ttacacggga ggcgccgtca ttccgtccgc ccagcgttat gtctccgccc gcgagttcca
    15241 gcgcagtaag gctgttgccc gcgccgttca ggacgatgtt tccttccgcg gaactgagca
    15301 tggaatcatt cccggtgaag ttgccttcca cggtgagggt ttccgcacct ttcttgacaa
    15361 aatccacatg gtccccgctg atggttccgc cgtagctgtt gccgccggcg tcaacgttct
    15421 gaaccagatc caccacggcg tggttggagg ccgcatcatc cgccgtattc gtcacgacca
    15481 gcgcaccatc gctgccaacc aggttgctga ctttcaggcc gtccccgttc cgggaggctt
    15541 ccggagcccc gttcaggctc acatgaagcg tggtgccatt aatgccgaca gccttgtagg
    15601 gatccagcgc ggcgtaatcg ctgatattgg ggtcgtctga attgggggtg gtgtccacca
    15661 gatagacaag gtccgtattg ccgctgacca tcagcgtccc gtccgcaccc aggacttccg
    15721 tcacggtata gccgagggaa gccaggagag gagagaatcc gatttgcttg aagttgtcca
    15781 cagcgagggt tcccgttgtc agtacaagcc ctacgccgtc agtggaatcc cggttggcgg
    15841 caagcaggtc cagaacgccc tggttgctga ggttgatggt tgtgtcggcg gcggaaagcg
    15901 tcaggctgtc cgcatcaatg acgccctgtc cggttgttcc gcccgcggta aggctgccgg
    15961 aatccagttt cagcgtcacc gtcttgcccg tcatgtccag agccccggaa acgcctgtaa
    16021 gccgggagta atcctccatg acgatggagc cgaccaagga accggacaaa ccgcccaggt
    16081 tgatcgtatt caggtctccc tgcgttccgg cggaagcggc cacttccaca ttcccggcgg
    16141 ttttggcttc cgcgttttcc aggctgccct tcgtaatcag aatgacgttg gccgcatcca
    16201 gagaggacag attgagaacg ccgttattga cggtgacccg tccggccccc agggagtcag
    16261 cccctcccaa agtaacggtg cccgttcccg cgagggtggt ggaaccggtg aacccggtgt
    16321 tgccggccgc cagcgttatc tctccggcag tatcgatgac cagggaaccg tctccggaga
    16381 gggacccggc ccaggcgctc ccgtcaccca gacgcgccgt agcgccgccc acaatggaga
    16441 gtgcgcccag gaaggtgttc gctccggtga gttccagcgt tccggcgttt acggataccg
    16501 tgctgccggc tgtgccgctg atgacgcctc cgtaggagaa atcgcgggca aaggccagcg
    16561 tggagttgtt ctggatgtca atgctgtccc ccagtttggc cacattggcg gaattcacgg
    16621 taaccgtgcc gcggtgcacc ttaagctgac cgtccaggtt gacgccgccc gccagggtaa
    16681 tattgcccgc gccctgggtg gagaacgccg ttccgctcaa atcgccgctg aaggtgaaat
    16741 ccttggtggc aaagacctgg ttgcccgtaa agacaacgtc attggcaaac gttcctccgg
    16801 ctgttccgtt ccattccgta cggacgttgg aatccgccag tttcagcgtg ccgtccgcac
    16861 ccatcgttac gttgttcaac tggaaatagc cggacgtcac ggacaggatc ccctggaatt
    16921 ccgtactcat gttcagaaca ttggccccat agctggttcc caggcccacg gaaacggtac
    16981 cagtgccgga agcattcagg ttcagcgccg agttgtcatt agccccgctg accgtcagta
    17041 cggaaccgtc cgccagttcc acagtttttc cattggccag agccttggcg acggtggcgg
    17101 tcacctcccc gcccagtatc atggaaccgc ccgtccaggc catgttgtct gcggtaaacg
    17161 ccgtggcaaa agaaccggaa gccagattga ggctgccgcc ctgcaggttg atcatgccca
    17221 ttcccggctg aacttccgcg gtagccagcg tgagcatgcc gtccgtaacg gtaatggcgc
    17281 cggaccccag ggagttggcg acctgagcca ccagttcgcc ctgctgaacg gaaatatccc
    17341 cgttccagcc cgtgttgtcc aaattaaggg tcaacttccc ttcgccacgc ttggtcagcg
    17401 ttccctgggc gatttttccg gagccgtcgg aaacgaagac atagtcgctg ccggcggcgt
    17461 tgttgaccgt gatggaggcc ggattcaccg ccccggacag ggtgacggtt cccgctccgg
    17521 ccgtgttgaa gatcagatcc ttcccggcag ccgtttccgc ggaaccttca atgccccaca
    17581 tggtgcccgt gttcgtatcg ctccagttca cgccttccgt tccctgccag atccacacgt
    17641 ccccggcgga agtcactacc agcttaaggg cagtattggt ctgctgcagt tcgtaaatca
    17701 gcgtttcgtc tccgacatac ccggcccagt taaagacggc gctggcggaa tcaagaccgc
    17761 tggcggcgga aatcagggta tattccccgg cttccgtaat gccttcaagc ccgttcagcg
    17821 taaggttgaa cgttccggag ccgaaagccc cacccactcc gagcgaggag ctgatatcca
    17881 gcgtcagcgc ggcgttggca gccaggttta aagcgcccgc agtcgtcatc cgcgtattgg
    17941 ccgccatcgt gatgttccgc agggaagtag cccctgaggc agtaagggcg agcgttcccc
    18001 cctgaatatc cgtcagcccc gtgtagctga ccggtcctcc cagcgtcagc gtctcatcgc
    18061 cgactttggt cagggacaaa acgccggatt cgtcatacgc aatggaagtg gccccgtacg
    18121 caagaacaat accgcggtct gtgagcgtgc cgttgtacgt gccggatccc accgtcaacg
    18181 tacgcgcgcc gcctacggct cccacttggg aattcgccgt tccgtccaga gaggcaatct
    18241 caacatcccc cagcacgcgc atgaaggcaa atccggtagt gtccgttccg gatgtcagag
    18301 tgacaccccc ctgagaaacg gaagtgcgca gatccagccc ggcgctgtag ccgtttgagg
    18361 cattcatggt gatcattccg gtaaatccgg aagcgtctcc gctgatgatg agtttgccgt
    18421 tggcattgta cctgccgtcg cccgctccgc ggctgtacgt cagggaaccg gctccggtga
    18481 gcgtcccggt gaaccccatt tccttggccc agttgtccct gcccaccaga gagactgccc
    18541 cgttgacggt aacggttccc gtaaagtcat gctgataatt ggttgcgttt gcctgggaag
    18601 cgtccaccca tttcagagaa acggcatcag acgcgttt
//
