LOCUS       c00047_gnlPro..        13814 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|BNHILMBH_47.
ACCESSION   c00047_gnlPro..
VERSION     c00047_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-05 13:59:16
            Original ID  :: gnl|Prokka|BNHILMBH_47
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 13814
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..13814
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[306:3814]"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      307..3814
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
     cand_cluster    1..13814
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /kind="single"
                     /product="Fumarate2succinate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..13814
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Fumarate2succinate"
                     /region_number="1"
                     /rules="(Succ_DH_flav_C and FAD_binding_2 and (Fer2_3 or
                     Fer4_7 or SucD_FumR))"
                     /tool="gutsmash"
     CDS             189..293
                     /locus_tag="ctg47_1"
                     /transl_table=11
                     /translation="MRKQLSGILFLVQGNLVMKKLPTADAAGSFYRAS"
     CDS             complement(307..1137)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Fer2_3"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_8"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052:Succinate dehydrogenase-2Fe-2S iron-sulfur
                     cluster binding domain (Score: -1.6; E-value: 9.2)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg47_2"
                     /sec_met_domain="Fer2_3 (E-value: 1.1e-23, bitscore: 74.1,
                     seeds: 38, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_8 (E-value: 3.5e-11, bitscore: 34.2,
                     seeds: 153, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 1.9e-06, bitscore: 19.0,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LPSAATSKDSQYINTQKKDYNMAKTLNLTLKVWRQENREAKGRIE
                     TYAAKDIPVDASFLEMLDIVNEGLVKEGKEPIHFDHDCREGICGMCSLTINGIPHGPER
                     QVTTCQLHMRKFKDGDTVWIEPFRAKAFPILRDLMVDRSALDRIIAAGGYIDVRTGSAP
                     NANNIAVEKVKADAAFDAAACIGCGACVASCKNASAMLFTSAKIAHLNLLPQGQPERSK
                     RVLAMMKQMEAEGFGNCTNQYECEAACPKGISVDNIARLNRDFMRANAKEGLCF"
     CDS             complement(1115..3064)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Succ_DH_flav_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: FAD_binding_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1027:FAD binding domain (Score: 175.9; E-value:
                     4.8e-54)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg47_3"
                     /sec_met_domain="FAD_binding_2 (E-value: 1.9e-54, bitscore:
                     175.9, seeds: 62, tool: rule-based-clusters)"
                     /sec_met_domain="Succ_DH_flav_C (E-value: 4.7e-38,
                     bitscore: 120.8, seeds: 739, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPDAKIPSGPIQDKWSKYKLESKLINPNNKRKYTVLVVGSGLAGA
                     SAAATLAELGYNVKCFCYQDSPRRAHSIAAQGGINAAKNYQNDGDSVYRLFYDTVKGGD
                     FRAREANVYRLAEVSSNIIDQCVAQGVPFGREYGGLLDNRSFGGAQLKRTFYARGQTGQ
                     QLLLGAYQALEKEVAKGHIEMFSRHEMMDLVLVDGEAKGIVTRNLVTGEIKSYAGDTVL
                     LCTGGYGNVFFLSTNAMGCNVTAAYKAYKRGAFFANPCFTQIHPTCIPVKGDYQSKLTL
                     MSESLRNSGRIWVPKSRETAXXXXTAEKIRKKEIKPSDVPEEERDYYLERKYPSFGNLA
                     PRDISSRAAKEACDDGRGVAVTGKGVFLDFADEIKRMGREWIDGQYGNLFDMYEEITDD
                     DPHETPMMIYPASHYTMGGLWVDYNLMSNVKGLHVLGEANFSDHGANRLGASALMQGLS
                     DGYFVIPATLPAYLTTTKPGAVTTAAPEFKAAEDEVKERINKLLNVKGTKTVDSFHREL
                     GLIMWEDCGMARTEESLTHAIERIPQLRKEFWENVRVTGTADGINAELEKACRVADFLE
                     FAQLLCYDALNRQESCGAHFRVEYQLPDGEAKRNDDEYAYVAAWEYTGVDSLPVLHKEP
                     LTFENVHLAIRSYK"
     CDS             complement(3113..3814)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: SucD_FumR"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg47_4"
                     /sec_met_domain="SucD_FumR (E-value: 1e-13, bitscore: 42.0,
                     seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNALVKTICTFVTSSIGRKIIVALTGLCLVLFLAGHLAGNLLIFG
                     GPEWINTYAHGLHSMPEAALWGIRAGLAVIFIIHVWLTIQLKLENHAAREPYVFKNTIK
                     ATLSSRYMIYTGLTVLVFLIYHLYQYTLRVGYDPAQFTTFISDGTVETFDVYKMIVTGF
                     SNVWCSAFYILAVLMLFSHLRHGVQSIFQTVGVDSRKIRPFYNFIAIAYGAIICLGFIS
                     VPVSVLLGIIK"
     CDS             4015..4287
                     /locus_tag="ctg47_5"
                     /transl_table=11
                     /translation="MKRSKKEVLDADFAAARAGVLDVAAFLDRVDRGEGEADFRYHALM
                     DVLPLLSASGPGRVRAILEALSYRDDTVPETAAAKAACGAPNLSK"
     CDS             4290..5105
                     /locus_tag="ctg47_6"
                     /transl_table=11
                     /translation="MMAFIEPHIHMVCRTTDEYRAMAQAGCLAVGEPAFWAGYDRSSAD
                     GFRDYFVQLTECEPARAAKFGMDHYTWLCINPKEAQDVAFARDVMKLIPEFIDRPNVLG
                     IGEIGLNRNTSHEMTIFEEHLDLAVRLNQLVLIHTPHLEDKLKGTVMILSALKNRPDLD
                     PCRVLVDHCEEHTFPLVKEAGYWAGLTLYPTSKLNPKRAADILELYGMDRVWANSAADW
                     GDSDPLALTALACELRRRGFSRQETERLLLENPETFMGQSPKFRKVSSR"
     CDS             complement(5139..5372)
                     /locus_tag="ctg47_7"
                     /transl_table=11
                     /translation="MNLQKQQLLLRLFRYFKSRKGEPRFFNKRNICLLAAAGAYILTPD
                     EFLFDGIGRLGLLDDAAVILGAVLTVFFPDGD"
     CDS             complement(5804..6511)
                     /locus_tag="ctg47_8"
                     /transl_table=11
                     /translation="MNKLLSTLILSVGMSLSATAATSLLDSSIVGYSDFASQTADFGTL
                     KDSVSITSDDSNLTLSGITFNGYGANNRDVMSVTMVLDLSKINTPDAYTALFNAKNSSV
                     SWGVGLNTDRKLQGLWNNTSYSGPVVDTPLGTEGSLTISVVTGDLGTRIYFGDSTTYYS
                     NSGLKFGNQQIDQILMDAGLAESIEQLYIHDSLLSQEQVGQLMSEIASIPEPATASLGL
                     LGLAALMMRRRRA"
     CDS             complement(6522..6710)
                     /locus_tag="ctg47_9"
                     /transl_table=11
                     /translation="VMRKDEEVLTKKLLFNGIFSFSECGGLMISVCRRTEATWKKATDS
                     KFVIQAQVHTLNLASFY"
     CDS             7062..8102
                     /locus_tag="ctg47_10"
                     /transl_table=11
                     /translation="VDSSVAAALLVEQGHDVVGAYMKNWVNDEGIPGECPWEQDIQDAL
                     AVAKTTGIEFRVIDLVDEYRARIVNYLIEGYRAGYTPNPDVLCNREMKFGVFLDYALEQ
                     GFDYVATGHYARRMDTPQGAFILRGRDPNKDQSYFLSLMRPDQIARAVFPLGDLLKPEV
                     RVLAEKYGLPTARKKDSQGICFIGQVKMSDFLRHYLPDKPGKIVDTEGRTLGTHNGLHL
                     FTMGQRKGHGVASPREGVAYVVVGKDVQRNRLILGYEDASTRGLYASRAVVGGISNTLA
                     PLPARVMAQPRYRAKAEWASCEYLEEGKVRLGFDTPLRALAVGQVCAFYDGGKLLGGGF
                     FESIEP"
     CDS             8099..9448
                     /locus_tag="ctg47_11"
                     /transl_table=11
                     /translation="MTDPERTIAAQATAAGQGAIAVIRMSGPGCMDILKQCTPAAFTER
                     LRPRRATLVCIRDAEGAAIDQALVTWFPAPASYTGEDTAEISCHGGMLVTDRLLKRLYQ
                     CGASPAEPGEFTKRAFLNGRMDLTQAEAVMDVISAGSDLALKAAQTQLDGGIGAQVDEL
                     KDNLVHVLAHIEAYIDFPDEDISPDTASDLLARLRSMEEKLTALLKTAEGGRLLREGIR
                     TAIAGPPNVGKSSLLNTLLGYDRAIVSNIAGTTRDTVEESIQLAGLALRLIDTAGVRES
                     SDVIEQAGITRTNRALETADLVLEVADASTPRIQDFPAPVLTAPRLLILNKCDLGVHPD
                     WKAVPGIRFSCATGEGRKELEEAIIQAFSSSLPGETGSSLVAINARHQHELGLCREHVR
                     LASESISRQESPEFTALELREALTHLGEITGAVDTEDVLGAIFSSFCLGK"
     CDS             9507..9692
                     /locus_tag="ctg47_12"
                     /transl_table=11
                     /translation="VEGWQSSKNLFADIFIDSGLLIRYRYHVLCCAPFLSFSFSLWFLF
                     KPPFILPIMFPKIRGS"
     CDS             complement(9931..10146)
                     /locus_tag="ctg47_13"
                     /transl_table=11
                     /translation="MESPTTPPFWKNETRSVPNWRGKSLCVKYLLLMKGQSPSQVEEDN
                     PRDVMYPSQYRPVFCGSVMVSLKSYK"
     CDS             complement(10157..10366)
                     /locus_tag="ctg47_14"
                     /transl_table=11
                     /translation="MKGQHQGVVCVDSRAVLAPQVQGSIRFMIINVPFFQTLSVVGVCD
                     VQGFGHAGSVVNLNSPAGNGMTRT"
     CDS             complement(10476..11129)
                     /locus_tag="ctg47_15"
                     /transl_table=11
                     /translation="MFLSTCEIMSTIIGALAGSIASSRVKMDLFGVIVCGTLAALGGGT
                     VRDILLDIPVYWTLPSGEIFVLASVVTSLATFYVAQKYPPPMGTIRVADAIVLALFGMI
                     GTEKSYLHGYTPTVSVMMGICTGVAGGLLRDVLTGNVPYVFRPGELYATAALLGGVAYA
                     VLYYAGIDSSTCFVTGFMVTLSVRLAAIRWNWNLPSYIPLFTSDTDSPPEEPET"
     CDS             complement(11158..12009)
                     /locus_tag="ctg47_16"
                     /transl_table=11
                     /translation="MFPCHKKKHGYGLAPFRGRYYIPRMMQFCVLGSGSGGNATIVRAG
                     ETVLLVDAGFSAARLRDKMKSAGVEPDELDAILLTHEHADHMKGVHQFTRKHAVRVYAT
                     RHTAMCVQEKAPEAPWAYFEKGQSFRIGDIVITPFPTYHDAVDPVGFKFETERSSLGFI
                     SDTGQAPGCIAEYLAMVDSLVVESNYDPDMLAATPRRPWPLKQRIASAHGHLSNEQACD
                     LLRRIAHGALKNVVLAHLSAESNSPALAESLMRDTLHDMGLASTSLFCASQDSCLPWIR
                     VC"
     CDS             complement(11993..12091)
                     /locus_tag="ctg47_17"
                     /transl_table=11
                     /translation="MQVHYVVTSIHFNAPEMSTPYWKKVFFHVPMS"
     CDS             12095..12550
                     /locus_tag="ctg47_18"
                     /transl_table=11
                     /translation="MSSVSDNLFGAYTHKLDPKNRIAIPAEWRPSEGCALLLLSGRRLD
                     LPTVKAYTREKFQQLIDKIETTPGYTEAQIDLFIGKLYANCVEAVINAQGKLLIPKQMC
                     EHAQLSSSVRLAARRGYFELWEPSLYEEVSRRENASISDINQSYGIL"
ORIGIN
        1 cttgacagga tgccatccct tccgggcatc agtccaattc ctgtaatcaa tgtttctttc
       61 tctcgaagaa agatgggggc cgtcgctgtc ggacgggggc ttgcttaggt ttcgtccggc
      121 atttccaagt acggtctcct ggattactgg aacccttccg gtgtaacaat tttttacgct
      181 gcgcgacgat gaggaagcaa ctgtctggta ttttattcct ggttcaagga aacctggtaa
      241 tgaaaaaact cccgacagcc gatgccgccg ggagttttta cagagcgtct taagaaggaa
      301 tcttctttag aaacagaggc cttccttggc gttggcccgc atgaagtcgc ggttgaggcg
      361 ggcgatgttg tccacgctga tgcctttcgg gcaggcggct tcacattcat actggttcgt
      421 gcagttgcca aagccttccg cttccatctg cttcatcatg gccaggacgc gcttggaacg
      481 ttccggctgg ccctgcggca gcagattgag atgggcgatc ttggcggagg tgaacagcat
      541 ggcggaggcg tttttacagg aggccacgca ggcgccgcag ccgatgcagg cggccgcgtc
      601 aaaggcggcg tccgctttca ctttttccac ggcgatgttg ttggcgttcg gcgcggaacc
      661 ggtacgcacg tcaatatagc ctccagcggc gatgatgcgg tccagggcgg agcggtccac
      721 catcaggtcc cgcaggattg ggaaagcctt cgcgcggaag ggttcaatcc agacggtatc
      781 gccatccttg aacttgcgca tgtgaagctg gcaagtggtc acctggcgtt ccggcccgtg
      841 gggaatgccg ttgatggtca gggagcacat gccgcagatg ccttcccggc agtcgtggtc
      901 aaaatggatg ggttccttgc cttccttgac caggccttca ttgacgatgt ccagcatttc
      961 caggaaggag gcgtccaccg gaatgtcctt ggcggcatag gtctcaatgc ggcccttggc
     1021 ttcccggttt tcctggcgcc agaccttgag agtgagattg agtgttttag ccatgttata
     1081 atctttcttt tgagtgttaa tgtattggct atctttactt gtagctgcgg atggcaaggt
     1141 gcacgttctc gaaggtcagc ggttccttgt ggagaacagg caggctgtcc acgccagtgt
     1201 attcccaggc ggctacatag gcgtattcat cgtcgttgcg cttagcttcg ccgtccggca
     1261 gctggtattc cacgcggaag tgggcgccgc aggattcctg gcggttcagg gcgtcatagc
     1321 agagcagctg ggcgaattcc aggaagtcgg ccacgcggca ggctttttcc agttccgcgt
     1381 tgatgccgtc cgccgtgccg gttacgcgca cgttttccca gaattccttg cggagctggg
     1441 gaatgcgttc aatggcgtgg gtcaggcttt cttccgtgcg ggccatgccg cagtcttccc
     1501 acataatgag gcccagttcc cggtggaagg agtccaccgt cttggtgccc ttcacattca
     1561 ggagcttgtt gatgcgttcc ttcacttcgt cttccgcagc cttgaattcc ggggcggcgg
     1621 tggtgacggc gccgggtttg gtggtcgtca ggtaagcggg cagcgtggcg ggaatgacga
     1681 agtagccgtc agacaggccc tgcatcaggg cggaggctcc caggcggttg gcgccgtggt
     1741 cggagaagtt ggcttcaccg aggacgtgca gccccttcac attggacatg aggttgtagt
     1801 ccacccacag gccacccatg gtgtagtggg aggcggggta gatcatcatg ggcgtttcat
     1861 gggggtcgtc gtccgtgatt tcttcgtaca tgtcaaacag attgccgtat tggccgtcaa
     1921 tccattcgcg gcccatgcgc ttgatttcat ccgcaaaatc taggaagacg cccttgccgg
     1981 tgacggccac gccgcggccg tcgtcgcagg cttccttggc ggcgcgggag gaaatgtcgc
     2041 gcggagccag gttgccgaag gagggatact tgcgttccag gtagtagtcc cgttcttctt
     2101 cgggaacatc ggaaggcttg atttcctttt tacggatttt ttctgcggtt nnnnnnnnnn
     2161 ctgcggtttc acgggacttg ggcacccaga tgcggccact gttgcggagg gattccgaca
     2221 tcagcgtcag tttggactga tagtcgccct tgaccggaat gcaggtgggg tggatttgcg
     2281 tgaagcaggg gttggcgaag aaggcaccgc gcttgtaggc cttgtaggcg gcagtgacgt
     2341 tgcagcccat cgcgttggtg gacaggaaga acacgttgcc gtagccgccc gtgcagagca
     2401 ggacggtatc ccctgcgtag gatttgattt cgccggtaac cagattgcgg gtgacgatgc
     2461 ccttggcttc gccgtccacc agcaccagat ccatcatttc atggcgggag aacatttcaa
     2521 tgtgtccctt ggccacttcc ttttccaggg cctggtaggc acccagcagt agctgctggc
     2581 ccgtctgtcc gcgtgcgtag aaggttcgct tgagctgggc gccgccgaag gagcggttgt
     2641 ccagcaggcc gccgtattca cggccgaagg gaacgccctg ggccacacac tggtcaatga
     2701 tgttggagga gacttccgcc agacggtaga cattggcttc acgggcgcgg aagtcgccgc
     2761 ctttaacggt gtcgtaaaac aggcggtaaa cggagtcgcc gtcgttctgg tagttcttgg
     2821 ctgcgttaat gccgccctgg gccgcaatgg agtgggcgcg gcgggggctg tcctggtagc
     2881 agaagcattt gacgttgtag ccaagttcgg caagcgtggc ggcagcggag gcgccagcca
     2941 ggccggaacc taccacaagc accgtgtact tgcgcttgtt gttcggattg atcagtttgg
     3001 actcaagttt gtacttggac catttgtcct gaatagggcc ggagggaatt ttggcatccg
     3061 gcatccagtc gcttacggga aaattaatca tgactttgag aggagttgat ggttatttga
     3121 tgatacccag aagaaccgag accggcacgg agatgaagcc caggcagata atcgcgccgt
     3181 aggcgatggc gataaagttg tagaagggcc ggattttgcg ggaatcgacg cccacagtct
     3241 ggaagatgga ctgtaccccg tggcgcagat ggctgaacag catcagaacg gccaggatgt
     3301 agaaggcgga gcaccatacg ttggagaatc cggtcacgat catcttgtac acgtcaaagg
     3361 tttccaccgt accgtcggaa atgaaggtgg tgaactgggc ggggtcgtat cccacgcgca
     3421 gggtgtactg gtacaggtgg tagatcagga acaccaggac ggtcaggccg gtatagatca
     3481 tgtagcggga ggagagcgtc gccttgatgg tgttcttgaa cacgtagggt tcgcgggccg
     3541 catggttttc cagcttcagc tggatggtca gccagacgtg gatgatgaag atcaccgcaa
     3601 gccccgcgcg gattccccag agggctgctt ccggcatgga gtgcaggccg tgggcgtagg
     3661 tgttgatcca ttcagggcct ccgaagatga gaaggttgcc tgccaggtgt cccgcaagga
     3721 acaagaccaa acataacccc gtcagagcca caatgatttt gcggccgatg gaggatgtca
     3781 cgaatgtaca tatggttttt actagtgcat tcataggcgc tctaatgaaa taaatgcgtc
     3841 ttcacaggat gcctggttca agcccggatg gcaagcctct tcttgaattt ccggcgcttt
     3901 tcggattttt gaaaagccgg ggaaagatgt tgctgtttat cagtttggaa tggttatcat
     3961 tttgttgcct gttccggctt gacgaggctt tccgcatagg cgtatcgtct gtgcatgaaa
     4021 agaagtaaaa aggaagtgct ggacgcggat ttcgcagcgg cgcgcgccgg cgttctggat
     4081 gtggccgcat ttctggaccg ggtggaccgc ggggaagggg aggcggattt ccgctaccat
     4141 gccctgatgg atgttcttcc cctcttatcc gcatccggcc ccggacgcgt ccgggccatc
     4201 ctggaagccc tttcctacag ggatgacacc gtgccggaaa ccgccgcagc caaagcggcc
     4261 tgcggagccc cgaacctcag caaataagaa tgatggcttt catagaacct catatacata
     4321 tggtgtgccg caccacggac gaataccggg ccatggcgca ggccggctgc ctggcggtag
     4381 gggaaccggc gttctgggcc ggttacgacc gttcgtccgc ggacggtttc cgggattatt
     4441 tcgtacagct tacggaatgc gaacccgcca gggcggccaa gttcggcatg gaccattaca
     4501 catggctgtg catcaatccc aaggaggcgc aggacgtggc tttcgcgcgg gatgtgatga
     4561 agctgattcc ggagttcatc gaccggccca atgtcctcgg catcggggaa ataggactga
     4621 accggaatac ttcccatgaa atgactattt ttgaagagca tctggatctg gcggtgcgcc
     4681 tcaaccagct tgtgctgatt cacactcccc atctggaaga caagcttaag gggaccgtaa
     4741 tgattctttc cgccctgaaa aaccgtccgg atctggaccc ttgccgcgtg ctggtggatc
     4801 actgtgagga acataccttc ccgctggtga aggaggccgg ttactgggcc gggctgaccc
     4861 tttatcccac cagcaagctg aatcccaagc gggcggcgga tattctggaa ttgtacggaa
     4921 tggaccgtgt ctgggccaat tccgcggcgg actgggggga ttccgatccc ctggcgctga
     4981 cggccctggc ctgcgagctg cgcaggcgcg gtttttcccg gcaggaaacg gaacgtcttc
     5041 tcctggaaaa tccggagaca ttcatgggac agtccccgaa gttccggaaa gtgtcgtccc
     5101 gctaattccg cccgaggcgc ggcggagggt acggccctct agtccccgtc cgggaaaaag
     5161 acggtgagga cggcgcccag gatgaccgcc gcgtcatcca gaaggcccag cctgccgatt
     5221 ccgtcaaaca ggaattcgtc gggagtcagg atgtaggcgc cggcggcggc cagaaggcat
     5281 atattccgtt tgttgaaaaa acgcggttct ccttttctgc ttttgaaata ccggaacagg
     5341 cgcagtagca gctgctgttt ttgaaggttc atggacggga acgggggata aaggttcaag
     5401 ctcagccatt ttcccactcc ttttccctgt ttcggggaag gagtctgttg ccgacggacg
     5461 gaaaccgcag cgatccggac cgtgcgggga aatggattgc tgaaaggatg ggctgttccg
     5521 gatgctgagg gaagccgggc tttgcatgct ccggttccgg ctgtcccggc atgggaaaaa
     5581 ggggcgtgta cggaagtggg gcggggccgg aagctcttga aatgaccctc ccgggggagc
     5641 ctgaatgcca tttccccgtc aagtgctggc cgtgagggta ccgcagcaaa tggaagcttc
     5701 ttcccccctg ttttttccgg cagatgtttg aacggataag gaaaaggccg gctcacgatt
     5761 ttgtgagccg gcctttgaat atagggaggc ggacggtaca ggcttatgcc ctgcggcggc
     5821 gcatcatcag cgcggccagt cccagcaggc ccagggaagc cgtggcgggt tccgggatgc
     5881 tggcgatttc actcatcagt tgaccaactt gttcctggga aaggagggag tcgtgaatgt
     5941 agagctgttc gatggattca gccagtcctg cgtccatgag aatctgatca atttgctggt
     6001 tgccgaattt caggccgctg ttggaatagt acgtagtgct gtctccaaaa tagatgcggg
     6061 tgccaagatc tccggtgact acggaaatgg tcagggaacc ttccgtgccc agcggggtgt
     6121 caacgacagg cccgctgtag gaggtgttgt tccataatcc ctggagtttc cggtccgtgt
     6181 tcaggcccac gccccagctt acactgctgt ttttggcgtt aaacagagcg gtataggcgt
     6241 ccggagtgtt gattttggac aggtcaagaa ccatcgtcac agacataacg tcgcggttgt
     6301 tggcaccgta tccgttgaag gttatcccgg ataacgtcag attgctgtcg tcagacgtga
     6361 tggaaacgga atctttcagg gtgccgaaat ccgccgtttg ggaggcaaag tccgaatatc
     6421 ccacgatgga gctatccagc agagaggtag ccgcggtagc gcttaggctc atgccgaccg
     6481 aaagaatcag ggtggataat aatttattca tggtcagtat cttaataaaa tgatgcaaga
     6541 ttcaatgtat gtacttgtgc ttgaataacg aatttggaat ccgtagcttt tttccaggtg
     6601 gcctccgttc tccggcagac tgaaatcatc agaccaccgc attctgaaaa actgaatatg
     6661 ccattgaaca acaatttttt agttaatacc tcctcatctt tcctcatcac ggaaatacct
     6721 cctgaaaaaa aatgaagggc cttacctctc catattccag cttcctgttt aaagaggtgg
     6781 taaattaatt ataatacttt tttctaattt attatattga ctacggattc caaattcgat
     6841 ttcagggaat gtgattaaaa atcaaaagcc tcccggatcg accgaatcat attccgcatc
     6901 agggaccgga tgccccattt ccacgctttt tgtcttggct tacggaaaca tctttggttt
     6961 acaggggcag gcggcaaagc ctttctcaaa gcggtccgcc ttatcacccc catatctttt
     7021 ccagcatcgt ggcacgcata cttgtaggct tatcaggcgg agtggacagc tccgtggcag
     7081 cggccctgct cgtggagcag ggccatgacg tagtgggggc ctacatgaaa aactgggtga
     7141 atgacgaagg cattcccggc gaatgcccgt gggaacagga cattcaggac gctctggccg
     7201 tcgccaaaac aacaggtatt gaattccggg tcattgacct ggtggacgaa taccgcgccc
     7261 gcatcgtgaa ttatctgatt gaaggctacc gcgccggata tacgcccaac ccggacgtat
     7321 tgtgcaatcg ggaaatgaaa ttcggcgtct ttctggatta tgccctggaa caggggttcg
     7381 actacgtcgc caccggccat tacgcccgca ggatggacac gccgcaaggg gctttcatcc
     7441 tgcgcgggcg ggacccgaac aaggatcaat cctacttcct gtccctgatg cgcccggacc
     7501 agatagcccg cgccgtcttt ccccttgggg atctgctgaa accggaagtg cgcgttcttg
     7561 cggaaaaata cggcctcccc acggcacgca agaaagacag ccagggcatc tgtttcatcg
     7621 gccaggtaaa aatgagcgat ttcctgcgcc actacctgcc ggacaagccc ggcaaaatcg
     7681 tggacacgga aggccggacg ctcggcacgc acaacggcct gcatctgttc accatgggcc
     7741 agaggaaagg gcacggcgtc gcctccccgc gggagggagt cgcctatgtg gtggtgggaa
     7801 aggatgtcca gcgcaaccgc ctgattctgg gatacgaaga cgcgtccacg cggggattgt
     7861 acgcgtcccg cgccgtggtc ggcggcattt ccaatacgct cgctcccctg ccggcccgcg
     7921 tcatggccca gccccgctac cgggccaagg cggaatgggc ctcctgcgaa tatctggaag
     7981 aaggaaaggt gcgcctgggc tttgacacgc ccctccgggc cctggccgtg ggacaggtct
     8041 gcgcctttta cgacggaggc aagttgctcg ggggcggctt ttttgaatcc atagaaccat
     8101 gactgacccg gaacgcacca tagccgcaca ggccaccgcc gcaggacagg gagccatcgc
     8161 cgtcatccgc atgagcggtc ccggctgcat ggacatcctg aaacaatgca cccctgcggc
     8221 tttcacggaa cgcctccgtc cgcgcagggc gacgctggtc tgcatccggg acgcggaagg
     8281 agccgccatt gaccaggcgc ttgtcacctg gttccccgcc ccggccagtt atacggggga
     8341 agataccgcg gaaatctcct gccatggcgg catgctggtg acggaccgcc tgctgaaacg
     8401 cctctaccaa tgcggggcct ccccagcgga accgggagaa tttacaaaaa gggcctttct
     8461 gaacgggcgc atggacctga cccaggcgga agccgtgatg gatgtgattt ccgccgggag
     8521 cgacctggcc ctgaaagccg cgcagaccca gctggacgga ggcatcggcg cccaggtgga
     8581 cgaactgaaa gacaacctgg ttcatgtgct ggcccacatt gaggcctata ttgattttcc
     8641 ggatgaagac atttccccgg acaccgcctc cgatctgctg gcgcgcctcc ggagcatgga
     8701 ggaaaaactg accgccctcc tcaaaactgc cgaaggcgga cgcctgctgc gggaaggcat
     8761 ccgcacggcg atcgccggac ctcccaacgt gggaaaatcc agcctgctga ataccctgct
     8821 gggatatgac cgggccattg tcagcaatat tgccggtacc acgcgggaca cggtggagga
     8881 atccattcag ctggccgggc tggccctgcg gctgattgat acggccggtg tccgcgaatc
     8941 ttccgacgtc attgaacagg caggcattac ccgcaccaac agggctcttg aaaccgcgga
     9001 tctggttctg gaagtggcgg atgcctccac gccccggatc caagacttcc ccgcccctgt
     9061 tctcaccgcg ccccggctgc tcattctgaa caagtgcgac ctgggagtcc atccggactg
     9121 gaaggccgtg cccggcatcc ggttttcctg cgccaccggg gaaggaagaa aggaattgga
     9181 ggaagccatt atccaggcct tttcctcctc cctgcccggt gaaacgggca gctccctggt
     9241 agccatcaat gcccggcacc agcatgaact gggcctctgc cgggagcatg tccggctggc
     9301 ttcggaatcc atctcccgcc aggaaagtcc ggaattcaca gccttggaac tgagagaggc
     9361 cctgacgcac ctgggagaaa tcaccggagc cgtggatacg gaggacgtgc tgggcgccat
     9421 tttttcctcc ttctgcctgg ggaaataaga agaagcttcc atcaacaggt ttttctgact
     9481 ccagattctt ctttcctctc cattctgtgg aaggatggca atcatccaaa aatttatttg
     9541 cggatatttt cattgattcc ggcttgttaa ttcgctatcg atatcatgtt ttatgttgcg
     9601 caccctttct ctctttttcc ttttcgctct ggttcctgtt caagccgcca tttattttgc
     9661 ccataatgtt tccgaagatt cggggttcat aaataccaaa aaatactgga acggagattc
     9721 cgatttatgc tgggcggcca cagccagcaa tatgctgcaa tggtggcaga ataattcctc
     9781 cggcattccg gctttcgttc ccaacggcca gaatgaaagc ggaagaacgg aaatttacga
     9841 tgtgttttgc aataattggg ccaataccgg gaaaggcata gaaataggcc tgcggtggta
     9901 cctgggaggg aaacctctca atcccaacaa ttatttatac gattttaagg aaaccatcac
     9961 tgaaccgcag aatactggcc gatactggga gggatacatt acatctctgg gattgtcctc
    10021 ttccacctgg gaaggcgact gccctttcat cagcagcaaa tacttcacgc aaagcgattt
    10081 tcccctccag ttcggtacag acctcgtctc atttttccag aatggcggcg tagtgggact
    10141 ttccattgct cctgcatcag gtccgggtca tgccattacc tgctggggaa ttgaggttga
    10201 cgacactacc ggcatggcca aatccctgta cgtcacagac tccgacaacg gacaaggtct
    10261 ggaaaaacgg gacgtttatt atcatgaaac ggatggaacc ctgcacttgg ggagcaagaa
    10321 cggccctcga atcaacgcat acgacgccct gatgctgccc tttcataatg ttccggaacc
    10381 ttccacggca gttctcacca ccctcgcggc gggaactgcc ttttgccgcc gcaggcgccg
    10441 acgctcttaa ggcttcacgg aaacattccc tcctgtcaag tttccggctc ttcaggaggc
    10501 gaatcggtat ccgaggtgaa taacggaatg taggaaggca ggttccagtt ccagcggatg
    10561 gccgccaggc gtacggaaag cgtgaccatg aagcccgtca cgaagcaggt ggaagaatca
    10621 attccggcat agtaaagcac cgcgtacgcc acgcctccca gcagggccgc ggtggcgtat
    10681 aattctccgg gacggaacac gtagggaacg ttgccggtaa gcacgtcgcg cagcaggccg
    10741 cccgccacgc cggtacaaat gcccatcatc acggaaacag tgggcgtata gccgtggaga
    10801 taggattttt ccgtgccgat catgccgaag agagccagaa cgatagcatc cgccacgcgg
    10861 atagtgccca tgggaggcgg atatttctgg gccacataaa aggttgccag gctggtgacg
    10921 acagaggcca ggacaaaaat ttccccggag gggagcgtcc agtacaccgg tatgtccagc
    10981 aggatgtcgc gcacggttcc gccgcccaac gcagccaggg tgccgcagac aatcacgccg
    11041 aacaaatcca ttttcacccg cgaggaagcg atggaacccg ccagggctcc aataatcgtg
    11101 ctcatgattt cacaggtgga gaggaacatg gcgggaggaa caggaaaaaa ggcatattca
    11161 gcagacccgt atccacggca ggcaggagtc ctggctggcg cagaacaggg aggtggaagc
    11221 cagccccatg tcatgcaggg tatcacgcat caggctttct gccaatgccg gagaattgct
    11281 ttctgcgctc aggtgggcca gcaccacgtt tttcagggct ccatgggcaa tccgcctcag
    11341 caggtcgcac gcctgctcat tggacagatg cccgtgcgca gaggcgatgc gctgcttcag
    11401 cggccaaggc ctcctgggag tggccgccag catgtccgga tcatagtttg attccaccac
    11461 caggctgtcc accatggcaa ggtattccgc gatgcagccg ggagcctgcc ccgtatcgga
    11521 aataaaaccc aggctggatc gctccgtttc aaatttgaat cccaccggat ccacggcgtc
    11581 atggtaagtg gggaagggag taatgacgat atcccctatt ctgaaagact gccccttttc
    11641 aaaataggcc cagggagcct ccggcgcttt ttcctggacg cacatggccg tatggcgggt
    11701 ggcgtaaaca cgcacggcat gctttctggt gaactggtgc acgcctttca tgtggtccgc
    11761 gtgttcgtgg gtaagcagaa tggcgtccag ctcatccggc tccactccgg cggacttcat
    11821 cttatcccgc agcctggcgg cgctgaaccc ggcatccacc agcaggacgg tttcccccgc
    11881 cctgacaatg gtggcatttc ccccgctgcc gctgcccaac acgcaaaact gcatcatgcg
    11941 cggaatataa taccgccccc ggaagggagc aagaccgtat ccatgctttt ttttatgaca
    12001 tgggaacatg aaaaaatact tttttccagt acggggttga catttcaggt gcattaaagt
    12061 gtattgaagt cactacgtag tgtacttgca tgcgatgagc agtgtatcag acaacctttt
    12121 tggtgcatac acgcacaagc tggaccccaa aaaccggatt gccattccgg ccgaatggag
    12181 gccctccgaa ggttgcgccc tgctcctgtt atccggccgg cgccttgatt tgccgaccgt
    12241 caaagcctat acgcgggaaa aattccagca actcattgac aagatagaaa caacgcccgg
    12301 ctatacggaa gcgcaaatcg acctgttcat cggtaaatta tacgccaact gtgtggaggc
    12361 tgtcatcaac gcccaaggca agctgctgat acccaaacaa atgtgcgaac acgcacagct
    12421 cagttcctcc gtccggctcg ccgcgcggag aggatatttc gaattgtggg agccctctct
    12481 ctatgaagaa gtttcccggc gtgaaaacgc cagcatctcc gacatcaacc aatcctacgg
    12541 cattctctag ctttccttca tgcccccaga ctcttccatt ctgcccaatc cccaggcacg
    12601 cccctgcgca acgcttgcat tgcgcccggg ctggcttgct tccggcctgg gcgtcggcgc
    12661 cagaaccggg ctgcatgcgg aactcacggc ttattccatc gttttctggg ggcacgacgc
    12721 ccttccggcg caggatatgg ttgcctggca acaggaaaaa gcacgcctta tggaggaaat
    12781 gtccctggcc gggcaaaaga gcgcctatgg caagctgggc gcattgtcct ccgacctgaa
    12841 ccgggctttt gacgaccata ttgagctttc tttacgcgcg ggcgcgggta cgcacatccg
    12901 cacggaggaa gtgcaggccc tggcaaacgg acttgcggaa gaaacgtcct gccgcgtact
    12961 ggcgtggagc gtctgccgca accatgtgca tgtggttgcg gagctgacgg aggagaaggg
    13021 agtggatgaa ctggtctgct cctggaaggc gctggccccc tccatgaact gggagaacgc
    13081 gtaccacacg gaagccctga aagcccggga agccgcggca agggcggatg ccctgatttc
    13141 cgaacttggg gatgacgcct ttgccgctgt tgatgcggaa gcggacggaa ccgtctccgg
    13201 aaacggtttc cggcacatta ccgttctgct gcatgaaacg gtggacatgc tgaaagcggg
    13261 ccccggcaaa ttcatcgtgg actgcacgct tggcggcggg ggccacacgg agcttctgct
    13321 ggaacagggc gccaccgtct ggggcattga ccgcgatgcg gacgcccgcc gcgccgccat
    13381 gctcaggctg gcgcgcttcg gttcccgttt caaggcgctc gccggcaact tccaggatgt
    13441 ggaaagcatt ctttcccagc agggggtttc ccgggtggac gggctgctgg cggatctggg
    13501 cgtttcctcc caccagcttg acaccgcctc ccgcggtttt tcttttcggg aagacggccc
    13561 tctggacatg cggatggata cccgcgccgc cttttccgcc cggaacctgg tgaatgaggc
    13621 cccggaagaa gaaatcgcag ccattctctg gcaattcgga gaggaacgcg cttcccgcgc
    13681 cattgcccgc gccattggga aagcccgcgc ccaggccccc atcaccacta ccgcacagct
    13741 tgcccgcatc gtggaatccg tcctgccgcg caaaggaagg cagcaccccg gcacccgcac
    13801 gttccaggcc ctga
//
