LOCUS       gnlProkkaLPLPJMKM_268   6182 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|LPLPJMKM_268.
ACCESSION   gnlProkkaLPLPJMKM_268
VERSION     gnlProkkaLPLPJMKM_268
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-11-18 08:46:09
            Original ID  :: gnl|Prokka|LPLPJMKM_268
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 6182
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..6182
                     /aStool="rule-based-clusters"
                     /category="PKS"
                     /contig_edge="True"
                     /core_location="[5448:6180]"
                     /cutoff="20000"
                     /detection_rule="(APE_KS1 or APE_KS2)"
                     /neighbourhood="20000"
                     /product="arylpolyene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      5449..6180
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(APE_KS1 or APE_KS2)"
                     /neighbourhood="20000"
                     /product="arylpolyene"
                     /protocluster_number="1"
     cand_cluster    1..6182
                     /SMILES=""
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(APE_KS1 or APE_KS2)"
                     /kind="single"
                     /product="arylpolyene"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..6182
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="arylpolyene"
                     /region_number="1"
                     /rules="(APE_KS1 or APE_KS2)"
                     /tool="antismash"
     CDS             complement(3..932)
                     /locus_tag="ctg268_1"
                     /transl_table=11
                     /translation="MSKLFIHIYNYLERHTALRYLLLAGSFLLMLFFAVQVKFEEDVTR
                     FFPDTQDARSTEIVFQNLKVKDKIIVMLSSADTVSGAVPSDRLVEAGDLLKDSLLAEAG
                     SEYITDIFSEVDENMIGKVTDFIYDNLPVFLTEDDYARMDSVLTADGIERRMRSNYLHL
                     LSPAGVALKSILPRDPVGLGTTSLEKLRDFQMTANYEIYDGHIFSRDMSTLLLFITPHY
                     GTGSTGKNEFLIDTIEKQLRETMDTYPGVKAEYFGGPSVGVYNARQIKSDTMLTMTIAL
                     VIIIVFITLVFKSRSAVILIILPVLYGAV"
     CDS             complement(929..2125)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1123:polyprenol-monophosphomannose synthase ppm1
                     (Score: 93; E-value: 4e-28)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg268_2"
                     /sec_met_domain="Glycos_transf_2 (E-value: 7.9e-29,
                     bitscore: 89.8, seeds: 256, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVTDTTYTFPEHQQQESQSVIVIPTYNNGGTLGQVLTDVLAYSFP
                     VIVVNDGSTDNTLEVLQGFPGIRVISYPDNRGKGYALNTGLKAAMEAGYRYAITLDSDG
                     QHYADDIPVFLKEIALYPDSLLIGARNLASDNMPGKNTFANKFSNFWFTLETGIRLSDT
                     QSGYRLYPLHKLKKMRLFTTKYEYELEIIVQAAWRDIRVTNVPVKVYYPPAGERISHFR
                     PLRDFTRISLLNSVLVLIALLWYWPWKCVRSVTKENVKKFVSKNITHSPESNVRIALAV
                     MFGVFMGIVPIWGYQMIVAGVLAHLMGLNKVITIVASNISIPPMIPFLLFGSYVTGGWV
                     LDQPVTLTLHEVTFDTIKDSLLQYLAGSMVFAVICGLLAGFVCLTLLSLFRKFERIAG"
     CDS             complement(2136..2489)
                     /locus_tag="ctg268_3"
                     /transl_table=11
                     /translation="MLTNFYTIEALAEQGGEYNCTIRLNPRHDVYKGHFPGMPVVPGVC
                     MLRMIKECMSTILDTPVRFQTVTSCKFLSVVNPSEQELLDFIFSLKDSNRLQVTANAGG
                     ATVLKLKATIVAE"
     CDS             complement(2629..3267)
                     /locus_tag="ctg268_4"
                     /transl_table=11
                     /translation="MKSLLSASLCLLLACCSCAPSITRECRKGETVSAAKGQFPPMIDA
                     SSRLCKYNMTIDFMRKHFSGLLLVKETEAGTYRTLFSTHFGLSLFDLEIGSDSLTVHHC
                     IEPLNKKKILSLFYRDFSVLFGLNIPSENKVTVYNCTDPQTDIVYKLSTPGFKGYYRID
                     GVENRMREIKLGSGLRKTTFRSFPDSSGQEAIRIRHTGLKLSIGLDAFN"
     CDS             complement(3245..3910)
                     /locus_tag="ctg268_5"
                     /transl_table=11
                     /translation="MIYLIRMEKKMNKYIYTFLLVVFCLPLAAQKDLTPLASVTAFQER
                     LKKEAASLSSIESDFTQEKFLDVFNEKIVSKGRFYYKQENMIRMDYTSPIDYQIIINGQ
                     KLKIVSEGKSNVVNLGSNQMMNEMKGMLAACMIGDLTVMSSAYRLEYYESPSLYVVKIR
                     PVSKSVQAYISEIVISIDKKDMSVQTLRLSENAKDYTEYYFTNRKYNTLTSDEKFVIR"
     CDS             complement(3873..4580)
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1235:polysaccharide deacetylase (Score: 120.6;
                     E-value: 1.4e-36)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg268_6"
                     /transl_table=11
                     /translation="MVWLVFIAVLICMGAFLFYASYSIRSGVYVKALCRGNTDKRVVCL
                     TFDDGPDPQYTPQVLDVLKKYQVQAAFFCIGAKVRENPAVMRRIASEGHHVGNHSDSHS
                     WKFPFLSRKKMRWDVSLCEDSLLSHAGPILTFRPPFGVTNPTVAWLVDDMRYTIIGWSI
                     RSFDTRGESEDKVFRRIIKQIEPGSVILLHDRMPGAASLLTRLLEHLKTINYEVIPLDK
                     MFDIPDPYGKEDE"
     CDS             complement(4585..5445)
                     /locus_tag="ctg268_7"
                     /transl_table=11
                     /translation="MFKKPVYIDKATASFERTDDGYVLKEPDYKFLIPNATLRRRMSRM
                     VRMGVATGLQCLEDATAPVDAILTATGLGCLADTEKFMNTILDHNEELLTPTAFIQSTF
                     NTIGAQIALLTGNHSYNTTYVHRAFSLESALLDAALLVQEEEAQSVLVGAVDEMTPTLQ
                     TILGRLGFWEKNKPGEGAAFFLLSGNRSPQCVAELRDMELFSGRFTEEEIKERMTAFLF
                     HNEASDAEVVFPDEYKQYCGEYLVAMSFALWQAYHRVLETDAPRSILLYNSFLDNHSFL
                     LIRRV"
     CDS             complement(5449..6180)
                     /NRPS_PKS="Domain: PKS_KS(Iterative-KS) (1-240). E-value:
                     1.5e-38. Score: 124.6. Matches aSDomain:
                     nrpspksdomains_ctg268_8_PKS_KS.1"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     arylpolyene: APE_KS2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1022:Beta-ketoacyl synthase (Score: 226.2; E-value:
                     1.3e-68)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg268_8"
                     /sec_met_domain="APE_KS2 (E-value: 4.4e-104, bitscore:
                     337.6, seeds: 16, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSTACSSAANAIMLGARMIRQGMLDVVVAGGTDALCKFTLNGFAS
                     LMILDKKPCRPFDVSRAGLNLGEGAGYLVLQSEATVGKTPYCLLSGYANANDAFHQTAS
                     SSEGTGAFLAMKGALDKAGLQPEEVDYINAHGTGTPNNDASESQAIRRLFGNRIPSFSS
                     TKAFTGHTLGAAGALEAVFSVLSLERGILYPNLNFTTPIEETGLIPVTRYQEGISLRSI
                     LSNSFGFGGNNASLLFRKYDK"
     aSDomain        complement(5461..6177)
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg268_8_PKS_KS.1"
                     /domain_subtypes="Iterative-KS"
                     /evalue="1.50E-38"
                     /label="ctg268_8_PKS_KS.1"
                     /locus_tag="ctg268_8"
                     /protein_end="240"
                     /protein_start="1"
                     /score="124.6"
                     /tool="antismash"
                     /translation="STACSSAANAIMLGARMIRQGMLDVVVAGGTDALCKFTLNGFASL
                     MILDKKPCRPFDVSRAGLNLGEGAGYLVLQSEATVGKTPYCLLSGYANANDAFHQTASS
                     SEGTGAFLAMKGALDKAGLQPEEVDYINAHGTGTPNNDASESQAIRRLFGNRIPSFSST
                     KAFTGHTLGAAGALEAVFSVLSLERGILYPNLNFTTPIEETGLIPVTRYQEGISLRSIL
                     SNSFGFGGNNASLLFRK"
ORIGIN
        1 aacacagccc cgtacaacac cggcaatata atcaggatca ccgccgaacg gctcttgaat
       61 accaacgtga taaaaacaat gattatgacc agtgcgatcg tcatcgtcag catcgtatcc
      121 gacttgatct gccgggcatt atatacaccg accgacggcc cgccgaaata ctctgctttc
      181 acaccgggat acgtgtccat cgtctccctt agctgcttct cgatcgtatc gatcaggaac
      241 tcattctttc cggtacttcc cgtaccgtaa tgcggagtaa taaaaagcag cagggtagac
      301 atatccctcg aaaagatatg cccgtcatag atctcataat tagccgtcat ctggaaatcg
      361 cgcaactttt ccaacgaggt agtccccagc cctaccgggt cacggggtaa tatacttttc
      421 aaagcgactc ccgcaggaga tagtaaatgc agataattac tacgcatacg gcgttctatc
      481 ccatcggccg tcagtacaga atccatgcgg gcataatcgt cctccgtcag gaaaaccggc
      541 agattatcat aaatgaaatc agtcactttc ccgatcatat tctcatccac ttccgagaat
      601 atatccgtga tgtattcgga accggcctca gccagcaaac tgtctttcag caagtcaccc
      661 gcctcgacca gccgatcgga cggaaccgca ccggaaacag tgtcggcaga cgacaacata
      721 acgatgatct tgtctttgac tttcagattc tgaaaaacga tctccgtact ccttgcatcc
      781 tgcgtatcag gaaagaaacg ggttacgtct tcctcaaact tcacctgtac ggcaaagaaa
      841 agcatcagta gaaagctacc ggccagtaac aggtaacgga gagccgtatg gcgttccaga
      901 taattatata tatgaataaa caacttactc atccggcaat acgttcaaac ttcctgaaca
      961 acgaaagcaa cgttaaacaa acaaagccgg ccagcaatcc gcagataacg gcaaaaacca
     1021 tactcccggc cagatattgc agcagcgaat ctttaatcgt atcaaaagta acctcgtgca
     1081 acgtcagcgt cacaggctga tccaataccc agccgcccgt cacataactg ccaaacaaca
     1141 gaaaaggaat cataggcgga atactgatat tcgaggccac aatggtaatg accttgttca
     1201 gccccatcaa atgcgccagc accccggcaa cgatcatctg atatccccaa atcggaacaa
     1261 tccccatgaa cacgccgaac atgaccgcca acgcgatccg gacattcgac tccggagaat
     1321 gggtaatatt cttagaaaca aacttcttca cattctcttt cgtcacactc cgcacacatt
     1381 tccacggcca gtaccataac aaagcaatca gaacaagcac cgagttcagc aaactgatac
     1441 gcgtaaagtc gcgcaacgga cgaaaatggc tgatcctttc ccctgccggc ggataataca
     1501 cctttaccgg gacattcgtc acgcgtatat ccctccaggc ggcctgtacg attatttcca
     1561 gttcatactc atatttcgta gtgaaaaggc gcatcttctt cagcttatgc aaaggataaa
     1621 gccggtaacc cgactgcgta tccgacagcc ggatgcctgt ctccagtgta aaccagaaat
     1681 tggagaattt attggcgaag gtatttttcc cgggcatgtt atcggaagcc agattacggg
     1741 ctccgatcag caggctatcg ggataaaggg ctatttcttt caggaaaaca ggaatatcat
     1801 ccgcataatg ctgtccatcc gaatcaaggg taatagcata acggtaaccg gcttccatag
     1861 cagccttcaa tccggtattc agggcatatc cttttccccg gttgtcggga taactgatta
     1921 cacggatccc gggaaatcct tgcagaacct ccaacgtatt atccgtagaa ccgtcattca
     1981 ccactataac aggaaatgaa taagccaata catctgtcag tacctgcccg agtgtccccc
     2041 cgttattata ggttgggatc acaatgaccg actgactttc ctgctgctga tgttccggaa
     2101 atgtatatgt agtatctgtt accatttata agtcgttact ctgctacaat cgttgctttt
     2161 agtttcagca cagttgctcc gcctgcattg gctgtaacct gtagcctgtt tgaatccttc
     2221 aaagaaaata taaagtccag taactcctgc tccgatggat ttaccacaga aaggaacttg
     2281 caactggtta ccgtctgaaa gcgaaccgga gtatctaaga ttgtcgacat gcattccttt
     2341 atcatacgaa gcatacaaac gccaggaacc accggcatac ccggaaaatg ccctttataa
     2401 acatcatgtc gcggattcag ccggatcgta caattatatt ccccgccttg ttctgcaaga
     2461 gcttctatcg tataaaagtt agtcaacatt cctttccaat atgcatttag tgtgacaaag
     2521 gtagggaagt ttttctatta tattggtcag tttcgaatct ttttgaaggt attaaccctt
     2581 gctatacaat atacctttcc tcagataatc agaatgatga agaatttctt aattgaacgc
     2641 atccaacccg atggaaagct tcagccccgt atgcctgata cggatcgctt cctgtccgga
     2701 actgtccggg aaagagcgga aagtggtttt gcgcaggccg gaaccgagtt tgatctcccg
     2761 catacgattt tccacgccgt ctatccggta ataacctttg aagccgggag tggatagctt
     2821 atatacgata tctgtctgcg ggtcggtaca gttataaaca gtcaccttat tttccgacgg
     2881 tatgttcaaa ccgaaaagaa ccgagaagtc gcgatagaac agagacagta tctttttctt
     2941 attcaacggt tcgatgcagt gatgtaccgt cagactatcc gaaccgattt ccaggtcgaa
     3001 aaggctcagt ccgaaatgcg tgctgaacag cgtacggtat gtgcccgcct ccgtctcctt
     3061 caccaataac aacccgctga aatgtttccg cataaagtcg atcgtcatat tgtatttaca
     3121 caggcgggaa gaggcatcta tcatgggagg gaattgccct ttcgcggcag acactgtttc
     3181 ccctttccgg cattcacgtg taatagaggg tgcacacgaa cagcaggcca gcaacaagca
     3241 gagactagcg gataacaaac ttttcatcac tggtcaacgt attgtatttc cggttcgtaa
     3301 aataatattc cgtataatcc tttgcattct ccgacaaacg cagagtctgt acagacatat
     3361 ctttcttatc tatcgaaatg acaatctccg agatataagc ctgtacgctc ttggaaaccg
     3421 gacggatctt caccacataa agggaagggg attcataata ttccagccgg taagccgacg
     3481 acatcactgt caggtcgccg atcatgcagg cggccaacat tcctttcatc tcgttcatca
     3541 tctggttgga accgaggttg actacattgc ttttcccttc ggaaacgatc ttcagcttct
     3601 gcccgtttat aatgatctga taatctatcg gagaggtgta atccatccgg atcatattct
     3661 cctgcttata atagaaacgg cctttcgata cgatcttctc attaaagaca tccagaaatt
     3721 tctcctgcgt gaagtcactt tcaatggaag aaagcgacgc tgcttccttt ttcagccgtt
     3781 cctgaaacgc ggtaacggat gccagcgggg ttaagtcttt ctgtgcagct aacggcagac
     3841 aaaaaaccac caacaggaat gtatatatat atttattcat cttcttttcc atacggatca
     3901 ggtatatcaa acattttatc caaaggaata acctcgtaat ttattgtctt caaatgttcc
     3961 agcaaacggg ttagcagaga agctgcaccc ggcatacggt cgtgtaaaag gataacggaa
     4021 cccggctcta tctgttttat tatccgacga aacactttat cttccgactc tccccgcgta
     4081 tcaaaagaac ggatactcca acctattatt gtatatcgca tatcgtccac caaccaagca
     4141 actgtcggat ttgtcacgcc aaaaggaggg cgaaaagtaa gaatcggccc tgcatgtgac
     4201 agtaaagagt cttcacacaa cgacacatcc caacgcatct ttttccgcga aagaaacggg
     4261 aatttccatg aatgactgtc agaatgattt ccgacgtgat gtccctccga tgcgatgcgt
     4321 ctcattacgg caggattttc ccgtaccttc gccccgatgc aaaaaaaggc tgcctgcacc
     4381 tgatactttt tcagtacatc gagtacctgc ggcgtatatt ggggatcggg accgtcgtcg
     4441 aaggtcaggc agacaacgcg cttatcggtg tttccccggc acaaagcttt cacatatact
     4501 cctgaacgaa tgctgtaaga ggcataaaag agaaatgcac ccatacagat taaaaccgct
     4561 ataaagacca gccataccat aaaactatac cctccttatt aatagaaacg agtgattatc
     4621 cagaaaagag ttatacagca ggatagaacg cggggcatcc gtctccagca ctcggtgata
     4681 ggcctgccac agagcaaagg acatcgctac cagatattcg ccgcaatatt gtttgtattc
     4741 atccggaaag accacctctg catcgcttgc ttcgttatga aacaggaagg cggtcatccg
     4801 ttcctttatc tcttcttccg taaaacggcc gctgaacaat tccatatccc ggagctccgc
     4861 cacgcattgc ggtgagcggt tccccgacaa aaggaaaaat gccgcccctt ctcccggctt
     4921 gttcttctcc caaaaaccca aacggccgag gatcgtttgc agcgtcggtg tcatttcatc
     4981 gaccgcccct accagaacag actgcgcttc ttcctcttga actagcaaag cggcatcgag
     5041 caaagcgctt tccagagaga aggcacggtg cacataggtc gtattgtaac tatggtttcc
     5101 ggtaagcaag gcaatctgtg caccgatcgt attgaaagtg gactggataa aggccgtagg
     5161 ggtaagcagc tcctcgttat gatccagtat cgtattcata aacttttccg tatcggccag
     5221 acatcccagg cccgtagccg tcaggatcgc atcgacagga gccgttgcgt cttcaagaca
     5281 ctgcaacccg gttgccaccc ccatacgaac catacggctc atccggcggc gaagcgtggc
     5341 attggggatc aggaacttgt agtccggttc tttcaacacg taaccatcgt ctgtccgttc
     5401 aaaagaggct gttgccttat ctatataaac cggtttctta aacataacct atttatcgta
     5461 tttccggaaa agcagggaag cgttgttccc tccaaaacca aaagagttag acaatatcga
     5521 acgcagggat attccttcct gataacgggt aacagggatt aatcccgttt cctctatcgg
     5581 tgtagtgaaa ttcagattgg gataaaggat accccgttcc agagagagta cgctgaatac
     5641 ggcttcgagg gctccggcag cccccaaggt atgcccggta aaggctttcg tcgaactgaa
     5701 agacggtatc cggttcccga aaagacgacg gatcgcctgg ctctcggaag catcgttgtt
     5761 cggggtacct gttccgtgcg cattgatata atccacctcc tccggttgca ggccggcctt
     5821 gtccaaagcg cctttcatgg cgaggaaagc acccgtacct tcggaagaag aagccgtctg
     5881 atggaaagca tcattggcat tggcgtaacc ggacaagagg caataaggag ttttaccgac
     5941 cgttgcttcc gactggagca ccagataacc ggcaccctcg cccagattca accccgcacg
     6001 cgagacatca aaaggacggc aaggcttttt atcgagtatc atcagcgaag cgaagccgtt
     6061 taaagtaaac ttgcacagtg catccgtccc tccggcaacc accacatcga gcatcccctg
     6121 ccggatcatc cgggcaccca gcataattgc gttggcggca gacgagcagg cggtactgac
     6181 cg
//
