LOCUS       c00140_gnlPro..        10592 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|LPLPJMKM_140.
ACCESSION   c00140_gnlPro..
VERSION     c00140_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-05 14:19:47
            Original ID  :: gnl|Prokka|LPLPJMKM_140
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 10592
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..10592
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[104:6090]"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      105..6090
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
     cand_cluster    1..10592
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /kind="single"
                     /product="TPP_AA_metabolism"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..10592
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="TPP_AA_metabolism"
                     /region_number="1"
                     /rules="(TPP_enzyme_C and not (PFL-like or PFL_6_pcresol or
                     PFL_9_tma or Gly_radical or Gly_430_pcre or Gly_8-9_TMA or
                     PFL_acetate1 or PFL_acetate2 or Gly_radical_scatole or
                     PFL_proline or PFL_toluene) and minimum(2, [ALS_ss_C,
                     AlaDh_PNT_C, Arginase, BKACE, BcrAD_BadFG, Beta_elim_lyase,
                     CPSase_L_D2, Cys_Met_Meta_PP, ELFV_dehydrog, GRDB,
                     Glu_syn_central, Glu_synthase, Gly_reductase, HAAA1, HG2B1,
                     HG2B2, HGD-D, HleuD1, HleuD2, HleuS1, HleuS2,
                     Homoserine_dh, ILVD_EDD, IlvC, Lactoyl-CoA1, Lactoyl-CoA2,
                     Lyase_aromatic, MAAL_C, OKR_DC_1_5_lysine,
                     OKR_DC_1_5_ornithine, OKR_DC_1_7_arginine, OKR_DC_1_C,
                     OTCace, PALP, Proline_reductase, Sacchrp_dh_C, TPL,
                     Thr_dehydrat_C, TnaA, Urocanase]) and not (POR or POR_N or
                     PFOR_II))"
                     /tool="gutsmash"
     CDS             complement(3..62)
                     /locus_tag="ctg140_1"
                     /transl_table=11
                     /translation="MEKGLRNIFYDFTTSYTPFS"
     CDS             105..1940
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ILVD_EDD"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg140_2"
                     /sec_met_domain="ILVD_EDD (E-value: 2.1e-218, bitscore:
                     715.1, seeds: 918, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MMKNPLRSSYSTEGRRMAGARALWRANGMKEEQFGKPIIAIVNSF
                     TQFVPGHVHLHEIGQQVKAEIEKLGCFAAEFNTIAIDDGIAMGHDGMLYSLPSRDIIAD
                     SVEYMVNAHKADAMVCISNCDKITPGMLMASMRLNIPTIFVSGGPMEAGNLDGRALDLI
                     DAMIEAADDSISDEQVEKVERSACPTCGCCSGMFTANSMNCLNEAIGLALPGNGTVVAT
                     HANRTRLFKKAAKMIVDNAFKYYRDGDDSVLPRSIATRQAFLNAMSLDIAMGGSTNTVL
                     HLLAVAHEAEVDFTMKDIDMLSRKTPVICKVAPSCSYHVEDVNRAGGIIGIMNELVKAG
                     LVDGSVKRADGLTLNEAIDQYCITSVNVTEEAINIYKSAPAHRFNLVLGSQESYYKELD
                     TDRATGCIRDVEHAYVKDGGLAVLYGNIAQDGCVVKTAGVDESIFRFAGPAKVFDSQDA
                     ACEGILKDQVVSGDVVVITYEGPKGGPGMQEMLYPTSYIKSKHLGKECALITDGRFSGG
                     TSGLSIGHISPEAAAGGAIGLVKDGDIIEINIPERTIHVKVTDEELAKRREAEEARGTK
                     AFTPPFRQRTVSKALKAYAKMVASADKGGVRIVED"
     CDS             1967..3667
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg140_3"
                     /sec_met_domain="TPP_enzyme_C (E-value: 2.7e-51, bitscore:
                     162.5, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDKQKITGSEALLKALIAEGVDTIFGYPGGQAIPIYDSLYDYRDQ
                     LKHILVRHEQGATHAAQGYARVSGKVGVTVVTSGPGATNTITGIADALMDSTPMVVIAG
                     QVPSPLLGTDAFQEVDVIGITQPITKWAYQIRRPEEIAWAVSRAFYIASTGRPGPVVLD
                     LAKDAQVGLVDYEYQKVDYVRSYQPEPDIREERIEAAASLINNAKKPFCLVGQGVILGG
                     AEEELKEFLLKNDIPAGSTVLGLSALPSDFPLNKGMLGMHGNVGPNRKTNECDVLIAIG
                     MRFDDRVTGDLKTYAKQAKIIHLDIDNSEIGKNVPVDVKVLGNAKHTIPMITALLEERK
                     RPEWNAEFEPDEKEEYNKVIEKELYPTEGQLKMGEVVRKVSEATDNDAILVTDVGQNQM
                     MGVRYFKYKQTRSVVTSGGLGTMGFGLPAAIGAKLGAPDRTVCFFTGDGGIQMTIQELG
                     TIMQENLNVKIIVLNNNFLGMVRQWQELFFNERYSNTIMKNPDFVAIAKAFGIASRAVD
                     KREDLDEAIAEMLNHDGAYMLVANVETCGMVYPMVPAGGSVTNMILGDK"
     CDS             3680..4234
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ALS_ss_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg140_4"
                     /sec_met_domain="ALS_ss_C (E-value: 9e-19, bitscore: 56.7,
                     seeds: 685, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNTKQLYTVIIFSENTVGLLNQITVIFTRRQLNIETLSVSPSAIK
                     GIHKFTITTFADEDTIDKVVKQIDKRVDILKAYYNTDEDLVYQEIALYKLSTELFIKMG
                     TVEDLIRKYNARILEMNEDCVVLEKSGHYDETQALFKELSETIGVLQFIRSGRVAITKS
                     KVERLSDMLSAMEKKLQEKHV"
     CDS             4271..5002
                     /locus_tag="ctg140_5"
                     /transl_table=11
                     /translation="MEKNKVGEFHFVTESYLMDFRGRITIPMIGTYLLHAASCHAADRG
                     FGYNDMTERHTAWVLSRLAIEMTSYPAMSESVTLYTWVDEVGKLFTSRCFELVNGEGKT
                     FGFARSIWAAIDMETRRPTLLDVEGLSAYITDRPCPIEKPGKIAPVENNTSGEPYRVKY
                     SDLDVNGHLNSIKYMEHLLDLFNISLFREKEISRFEIAYQSEGKYGMELTLHNQEVSPG
                     KYNMAICNDGKAISRAAVTWI"
     CDS             5044..6090
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: IlvC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) IlvN"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg140_6"
                     /sec_met_domain="IlvN (E-value: 9.8e-49, bitscore: 154.2,
                     seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="IlvC (E-value: 2.2e-44, bitscore: 140.3,
                     seeds: 295, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAVMNFGGVDENVVTREEFPLEKAREVLKDETIAVIGYGVQGPGQ
                     SLNLRDNGFNVIVGQRKGGKTWEKAVADGWVPGETLFDIEEACEKATIIQYLLSDAAQI
                     EVWPRIKKYLTPGKALYFSHGFGITYKERTNIIPPADVDVILVAPKGSGTSLRRMFLQG
                     RGLNSSYAIFQDATGKAWDRVIALGIGVGSGYLFETTFKKEVYSDLTGERGTLMGAIQG
                     LLLAQYETLRENGHEPSEAFNETVEELTQSLMPLFAENGMDWMYANCSTTAQRGALDWM
                     GPFHDATKPVFQKLYSEVACGNEAQRSIDTNSKPDYREGLEKELAALRESEMWRAGAVV
                     RKLRPENN"
     CDS             6592..9870
                     /locus_tag="ctg140_7"
                     /transl_table=11
                     /translation="MISVLLGAAGAIAANPTGPETMVVQQGNKVTGLVEDQMGPVAGAS
                     VVVKGTTIGTITDIDGKFTLDNVRRGAVIVISFVGLATQEITWNGQSILNVKLSDATQD
                     LDEVVVVAYGTAKKSTFTGSASVVKAEKLEKIMGSGFAEALQGMSAGVNVVNVQGNPGA
                     DARVEIRGIASMSGKADPLYIVDGMPYDGKLNQINPTDIESMTVLKDAAATSLYGSRAA
                     NGVVMITTKRGKSEKPRINFRGGWGTSDNAVKNPKKADPYQQLENTWYALYYDALLYDG
                     MNMQQAGDYASSQALTKQVKATKDSNGNLIYVTPFRHINENYVLHDGNGNPYMNPNLEY
                     VWDEDDWDVYKAIFSRKLRQDYSVDISGQANGGKTAYFFSGGYLDDQGYGNRQYYKRYS
                     FRTNLSTELFDWWKVAGSLSYSRHRQNLSGGASRAANFTTTLSSPWLRNEDNTGWVVSE
                     KTGERMYSYGKYTNNFFGAHILNNSGDYWDNPNDDSFDNNMGHILSAQVNTEFTLPFNL
                     KFRSALNIDDYWYRTMQYTSAVHGSGQTAPYGISILADGGYASRYNFNKRSTTWNNVLS
                     GEWMIGDHTISGLVGHEWYTWDSHYEQGWGEGIMELGKYELSNTTKNFGVSGGRDKYSL
                     LSFFGKVDYNFLNKYYLSASLREDGSSRFSSDHRWGTFWSTGGSWRISKEGFMEDLKWI
                     DNLSLRGSYGTTGNDKLIVRESNGKAGDEVLYGYQGTYESDDLYLKSGLKPSTYPTPDL
                     KWESNQQWNIGLDFSVFNRLSGTVEYYSRTSHDLLYYKELPLSAQVGSASGYNMNIGDL
                     RNSGIEITLNANILTTKDFRWDIDANMSTLKNEVTYLPTGPYTYSGTACTYKMEEGKSL
                     YEFIAPQYDGVNPETGVPGWLIRDGNGGWKRTEKQEEVTTDDFVYCGSAIPKVFGAITN
                     NFQFKGIDLSFMFYYSYGSKISDYTYKERIMNRPGVGVIQELVEDRWRQPGDADVLIPR
                     WSYNQYGATVKYADNFVFDNHYWRLRNLTLGYTLPKSLTRKALVENLRVYVTGNNLLTF
                     GPAKKRYTDPETGIMGNSYNGNAETDNGIQGSRRLYMVGIQITL"
     CDS             9889..10590
                     /locus_tag="ctg140_8"
                     /transl_table=11
                     /translation="MKRFINISFLSLVFAGMALTGCNDDLTTSSYVKVNDEDVLGNVSQ
                     LEKVLTSAYKQLYFNTDKGDRVYAGLPGFQMYVDASGADVISHTNMGGDQVTAYQYSNS
                     KTQADGNASKIWSMCYNVINRANIILTNVDAAAGDETQKKHIKGQALAMRGIQYFHLIQ
                     NYQQTYAIAKSKRGVILRTSSDDESHKVFSTVEEVYTQIVSDLTTAKTLLADYNPDDMW
                     LINSKICSGILA"
ORIGIN
        1 aaggagaaag gtgtgtaaga agttgtgaag tcgtaaaaga tatttcttaa gcctttctcc
       61 atatagagaa gggctttttt attgactaaa agataaaaac agatatgatg aagaatccgt
      121 taagaagctc ctatagcaca gaaggcagac gtatggccgg tgcccgtgca ttatggcgtg
      181 ccaacggcat gaaagaagaa cagttcggta aaccgatcat tgccattgtg aattcattta
      241 cccagtttgt accgggccat gtgcatctac acgagatcgg acagcaggta aaagcggaaa
      301 tcgaaaagct cggttgcttt gccgcagaat ttaatacgat cgctattgat gacggtatcg
      361 ctatgggaca cgacggaatg ctttattctc tgccttcccg cgacatcatt gctgacagtg
      421 tggaatatat ggtgaatgcg cataaggctg atgcaatggt ttgtatcagt aactgcgaca
      481 agattactcc gggtatgctg atggccagta tgcgtctgaa tattccgaca atctttgtat
      541 ccggcggtcc gatggaagcc ggtaatctgg acggacgtgc actcgatttg atcgacgcca
      601 tgattgaagc ggctgacgat tctatcagcg atgaacaagt agaaaaggtg gaacgttccg
      661 cttgcccgac ctgcggttgc tgttctggta tgttcacggc taactctatg aactgtctga
      721 acgaagcgat tggattggct cttcccggca acggaacagt tgttgcaaca catgccaacc
      781 gtactcgctt gttcaaaaaa gcggcgaaga tgattgttga taatgccttt aaatattatc
      841 gtgacggcga tgattccgta ttgcctcgca gtattgccac ccggcaggcc tttctgaatg
      901 ctatgtcgct ggatattgcc atggggggat cgacgaatac agtccttcac ctgttggccg
      961 tggctcatga agcggaagtc gattttacaa tgaaagacat cgatatgctt tcacgcaaaa
     1021 caccggttat ctgtaaagtg gctccgagtt gttcttatca cgtggaagat gtgaaccgtg
     1081 ccggaggtat catcggtatt atgaatgagc tggtaaaagc cggtctggtg gacggttccg
     1141 tgaaacgtgc ggatggtctg actttgaatg aggctatcga ccaatactgc attacctctg
     1201 taaatgtaac ggaagaagca atcaatattt ataaaagtgc tccggcccac cgtttcaatc
     1261 tggtgctcgg atcgcaggaa agttattata aagaactgga taccgaccgt gcaaccggat
     1321 gtatccgcga tgtggaacat gcttatgtga aagacggcgg tctggctgtt ctgtatggaa
     1381 atattgcaca ggacggttgt gtggttaaaa cagccggggt agacgaaagt atcttccgtt
     1441 ttgccggtcc tgccaaagta ttcgattcgc aggatgccgc ttgtgaaggt atcctgaaag
     1501 atcaagtcgt ctccggcgat gtcgtcgtta tcacctatga aggtcctaag ggtggtccgg
     1561 gtatgcagga aatgttgtat cctacctctt atataaagag taaacacctg ggtaaagaat
     1621 gtgcgctaat cacagacgga cgattcagcg gtggaacatc aggtttgtca atcggacata
     1681 tttctcccga agcggctgca ggcggagcga ttggcttagt gaaagacggc gatattatcg
     1741 aaattaatat tcccgaaaga accatacatg taaaggtgac agacgaagaa ctggccaaac
     1801 gccgtgaagc ggaagaggcc cgcggaacaa aagcctttac acctcctttc cgccaacgta
     1861 cggtatcgaa agcactgaaa gcatatgcaa agatggttgc ttcggccgat aagggcggtg
     1921 tacgaatagt agaagattaa taaacaccaa atactatatt ttagagatgg acaaacaaaa
     1981 gataaccggt tcggaagctt tgctgaaagc gctgatcgct gaaggagtag atactatctt
     2041 cggttatccg ggtgggcagg cgataccaat ttacgatagt ttatacgatt acagagatca
     2101 gttaaaacat attctggtgc gccacgaaca aggtgcaaca catgctgcac agggatatgc
     2161 ccgtgtttcc ggaaaagtgg gagtaacggt ggttacttcg ggtcccgggg caaccaatac
     2221 catcactggt attgccgatg cgctgatgga cagtacaccg atggtggtga ttgccggcca
     2281 ggttccgtct ccgctgcttg gaacagatgc tttccaggaa gttgatgtga tcggtatcac
     2341 acaaccgatt accaaatggg cttaccagat acgccgcccg gaagaaattg cgtgggccgt
     2401 ttcccgtgct ttctatatcg catcgaccgg tcgcccggga cctgtggtac tggatttggc
     2461 gaaagatgca caggtgggtt tggtagatta tgagtatcag aaagtggatt atgttcgtag
     2521 ttaccagcct gaaccggata tcagggagga acgtatcgag gcggctgctt cattgataaa
     2581 taatgccaaa aagccattct gtctggtagg gcagggggtt atcctgggag gagctgaaga
     2641 agaactgaaa gaattcttgt tgaaaaacga tataccagcc ggttctaccg tattgggctt
     2701 gtctgcatta ccttcggact tcccattaaa taaaggtatg ttggggatgc atggaaatgt
     2761 cggaccgaac cgcaagacaa acgaatgtga cgtgctgatt gctatcggta tgcgtttcga
     2821 tgaccgtgta accggcgacc tgaagactta tgccaagcag gcaaagatta tccacctgga
     2881 tatcgacaat tcggagatcg gaaagaatgt gccggttgac gtgaaagtgc tgggaaatgc
     2941 caagcatacg attccgatga ttacggcttt actggaagaa cggaagcgtc cggaatggaa
     3001 tgctgaattc gaaccggatg aaaaagagga atataataag gtaatagaaa aagaactcta
     3061 tcctaccgaa ggccaactaa aaatgggcga agtagtccgt aaggtttccg aagcaaccga
     3121 taatgatgcg attctggtta cggatgtagg tcagaaccag atgatgggtg ttcgctattt
     3181 caaatataaa caaacacgca gcgtagttac ttcaggaggt ttgggaacga tgggctttgg
     3241 ccttcccgcc gccattggag cgaagctggg agcgcctgac cgtacggtct gtttctttac
     3301 cggcgacggt ggtatccaga tgactatcca ggagttggga actatcatgc aggaaaatct
     3361 gaatgtaaag atcatcgttc ttaacaacaa tttcctggga atggtacgcc agtggcagga
     3421 gctgttcttc aacgaacggt attcgaatac catcatgaag aatccggatt ttgtagcgat
     3481 agccaaggct tttggtattg cttcccgtgc ggtagataaa cgggaagact tggatgaggc
     3541 gattgctgaa atgttgaatc acgatggtgc ctatatgttg gttgccaatg tggaaacttg
     3601 tggtatggta tatccgatgg ttccggccgg aggaagcgtg acaaacatga ttttgggtga
     3661 taagtaagga ggagaaacta tgaatacaaa acaattatat accgttatta tcttttcgga
     3721 aaacactgtt ggtcttctga atcagataac tgttatcttt acgcgccggc aactgaacat
     3781 tgagacgctt tctgtttctc cctctgctat aaagggaata cataagttta caattactac
     3841 ctttgccgac gaggatacga tcgacaaggt cgtaaaacag atcgacaagc gtgtggatat
     3901 cctgaaagcc tattataata cggatgaaga cctggtttac caggaaatcg ctctttataa
     3961 actgagtacc gaactcttta tcaagatggg gacggttgag gatctgatcc gtaagtacaa
     4021 tgcccgtatc cttgaaatga atgaggattg tgtggtgttg gaaaagagtg gtcattatga
     4081 tgagacacag gctttgttta aagaattgag tgagacgatc ggtgtcctgc aatttatccg
     4141 ttccggacgc gttgctataa cgaagagtaa ggtagaacgt ctgagcgaca tgttatctgc
     4201 aatggaaaag aagttgcagg aaaaacatgt ctgagaacaa caaggaaaca ttttgtaaat
     4261 aaagtaaatt atggagaaga acaaagtagg agaatttcat ttcgtaacag agtcttatct
     4321 gatggacttc cggggacgta ttacaatccc tatgatcgga acttatttgt tgcatgctgc
     4381 ttcttgccat gccgccgacc gtggattcgg atataacgat atgaccgaaa ggcataccgc
     4441 ctgggttctt tcccgtctgg ctatcgagat gacttcttat cctgccatgt ctgaatccgt
     4501 aactttatat acctgggtgg atgaggtcgg taagttgttt accagccgtt gctttgaact
     4561 ggtgaacggt gaaggcaaga cctttggctt tgcccgctct atctgggcgg ctatcgatat
     4621 ggaaacccgc cgcccgacct tgctcgatgt ggagggcctg agtgcttata tcaccgaccg
     4681 tccctgtccg attgaaaaac cgggtaaaat tgctccggtg gaaaacaaca cttccggcga
     4741 accttaccgt gtgaagtata gtgacctgga cgtaaacggc cacctgaaca gtatcaaata
     4801 catggaacac ctgctcgact tgttcaatat cagtctgttc cgagaaaaag agataagccg
     4861 tttcgaaata gcttatcagt ccgaaggaaa gtatgggatg gagctgactc tccataacca
     4921 ggaagtatcc cccggtaaat ataatatggc aatctgtaac gacggcaaag ccatcagccg
     4981 cgctgccgtt acctggatct gaaaaacaaa ttattttata tacattttaa tagtaaaaag
     5041 aaaatggcag taatgaattt tggcggcgtt gacgaaaacg tagtaacccg cgaagaattt
     5101 ccgttggaaa aggcaagaga agtattgaaa gacgaaacaa tcgctgtaat aggttacggc
     5161 gtacaaggtc ctggccagag cctgaacctg cgcgacaacg gttttaacgt aattgtagga
     5221 caacgtaaag gtggtaagac ctgggaaaag gccgttgctg acggttgggt accgggcgaa
     5281 acactgttcg atatcgaaga agcatgcgaa aaagcaacta tcatccagta tctgctttca
     5341 gatgctgctc agattgaagt ttggccgcgc atcaaaaaat acctgactcc gggtaaggct
     5401 ttgtatttct ctcacggatt cggtatcact tacaaagaac gtacaaacat catccctcct
     5461 gctgatgtag acgtaatcct ggttgctccg aaaggttcag gtacttcact gcgccgtatg
     5521 ttcttgcagg gtcgtggtct gaactcaagc tacgcaatct tccaggatgc aacaggcaaa
     5581 gcatgggatc gcgtgattgc actgggtatc ggtgttggtt ctggttactt gtttgaaaca
     5641 acattcaaga aagaagttta ttctgacctg accggcgaac gtggtacttt gatgggagct
     5701 atccagggat tactgttggc tcagtacgaa actttgcgtg aaaacggtca cgaaccttct
     5761 gaagcattca atgaaacagt agaagaactg actcagtcat tgatgccgtt gttcgcagaa
     5821 aacggtatgg actggatgta tgcaaactgt tcaacaactg cacagcgtgg tgctttggac
     5881 tggatgggcc cgttccacga tgctacaaaa ccggtgttcc agaagttgta tagcgaagtt
     5941 gcctgcggta acgaagcaca gcgttctatc gacacaaaca gcaagcctga ctatcgtgaa
     6001 ggtctggaaa aagaactggc tgctcttcgc gaaagtgaaa tgtggcgtgc aggtgctgtt
     6061 gttcgtaaac ttcgtcctga aaacaactaa taaatggtga tacattaata gttaaacatt
     6121 ttgtgatata aaaacggcaa tccggctttt cgggttgccg tttttttatg gtttatgtaa
     6181 tgcgttaatg gttaaaaaat gtttttgatt gcagctgtta ttgatttttc atcccaatat
     6241 gtatgtcatt gtttgaatgt ggattttaga taaaaaaatc aattaaatgg tggttaaaat
     6301 atatttatta gagcaataaa tatacataat tatgcttgta ttaaataatg ataagttata
     6361 tttgctgatg gagatactgt agtttgtaga gtggaaatat agaaggatgt tgtgtgtaat
     6421 gatcagtata tctttgtttt agttaacttt attttattga aatgtatgcc agtcactttt
     6481 atcttagaaa agtgtaacct ctaatgaaat gaacgctatt gtgattaatt ttatttaatt
     6541 aaagacttga atttagctat gtggaccaac tcaaaactaa ttagatcact aatgatttct
     6601 gtattattag gtgcggcagg tgcgattgct gccaatccta caggtccgga aacgatggta
     6661 gtacaacagg gtaataaggt aaccggcctg gtagaggacc agatgggacc tgtcgccgga
     6721 gcttctgttg tagtgaaagg aaccactatc ggtacgataa ccgatatcga tggaaagttt
     6781 acgctggata atgttcggcg gggagcggtt attgttattt cctttgtcgg cctggccact
     6841 caggagatca cttggaacgg gcaatctatt ttaaatgtaa aattaagtga tgcgacacag
     6901 gacctggatg aagtcgttgt cgtagcctat ggaacggcta agaaatcaac cttcaccgga
     6961 tcggcctccg ttgtaaaagc tgaaaaactc gaaaagatca tgggctccgg ttttgcggaa
     7021 gcattgcagg ggatgagtgc cggtgtgaat gttgtgaatg tacagggtaa ccccggagct
     7081 gatgcccgtg tggagatccg tggtattgct tccatgtccg gaaaggctga tccgttatat
     7141 attgtggacg ggatgcctta cgatggaaaa ctgaatcaga tcaatcctac ggacatagaa
     7201 tcgatgacgg tgctgaagga tgcggcggcc acttcgcttt acggttcgcg tgcagcaaac
     7261 ggcgtcgtaa tgattacaac caagcggggt aaatcagaaa aaccgcgtat taacttccgc
     7321 ggaggttggg gtacttcgga taatgctgtc aagaatccga aaaaagccga tccgtaccag
     7381 cagctggaaa atacctggta tgccttgtat tatgatgccc ttctttatga cggcatgaat
     7441 atgcaacagg cgggcgatta tgcttcgtca caggcattga ccaaacaggt aaaggctaca
     7501 aaagattcga atggtaatct gatttatgtc actccgttca gacatatcaa tgaaaattac
     7561 gtattgcatg acggcaatgg gaatccttac atgaatccta atctggaata tgtctgggat
     7621 gaagatgatt gggatgtcta caaagctatc ttctcccgta aactgcgcca ggattatagt
     7681 gtggatataa gtggtcaggc caatggtgga aaaacagcct atttcttctc cggcggttat
     7741 ctggacgacc agggatatgg gaaccggcag tattataaac gttattcttt ccgtaccaac
     7801 ctgagtacag agttgttcga ttggtggaaa gtggccggta gcctttctta ttcgcgtcat
     7861 cgccagaacc tttccggtgg tgccagccgt gcggctaact ttacgacgac tttgtcttca
     7921 ccctggttac gtaatgaaga taataccggt tgggtcgttt ctgaaaaaac aggggaacgg
     7981 atgtacagtt acggtaaata taccaataac ttctttggtg cccatatcct gaataactcg
     8041 ggtgattatt gggataatcc gaacgatgac agtttcgata acaatatggg gcatatcctg
     8101 tctgcccagg taaatacaga gtttactctt cctttcaacc tgaaattccg ttcggctttg
     8161 aatattgacg attactggta tcgtaccatg caatatactt ccgccgtaca tggcagcgga
     8221 cagactgcac cttatggtat ttctatactg gcagacggtg gttatgccag ccgttataat
     8281 ttcaataaac gttccaccac ctggaataat gtattgtctg gtgaatggat gattggtgac
     8341 catacgattt caggtctggt cggacatgag tggtatacct gggactccca ctacgaacaa
     8401 ggttggggtg aaggtatcat ggaactgggt aaatatgaat tatcgaatac taccaagaac
     8461 ttcggtgttt ccggcggacg tgataaatac tctctgcttt cgttcttcgg taaagtcgat
     8521 tataacttct tgaataagta ttacttgtcc gcttcgcttc gtgaggatgg ttcttcccgt
     8581 ttcagctccg atcatcgctg gggtacattc tggtcgacag gcggttcatg gcgaatatcg
     8641 aaagaaggtt ttatggaaga cctgaaatgg attgataacc tttcgttgcg tggtagttac
     8701 ggtacgaccg gtaatgataa gctgatcgtg cgtgaatcga atggtaaggc aggggatgaa
     8761 gtcctttacg gataccaggg tacttatgaa agtgatgacc tgtatctgaa atccggttta
     8821 aaaccatcta cctatccgac accggacttg aagtgggaaa gtaatcagca atggaatatc
     8881 ggtttagatt tttccgtatt caaccgactt agcggtacag tggaatatta ttcccgtact
     8941 tcccatgact tgttgtatta taaggaactg cctctctctg cccaggttgg tagtgcatcc
     9001 gggtataata tgaatatcgg tgacctgcgt aatagcggga ttgaaatcac attgaatgcg
     9061 aatatcctta caacgaaaga tttcagatgg gatatcgatg ccaacatgag tacgctgaaa
     9121 aatgaggtga cttatttgcc tacaggtcct tacacttatt ctggtaccgc ctgtacctac
     9181 aagatggagg aaggcaagtc tctgtatgaa tttatcgctc cccagtacga cggtgttaat
     9241 ccggaaaccg gagtacccgg ctggttgatc cgcgatggta acggcggttg gaaacgtacg
     9301 gaaaagcagg aagaagtaac gacagacgat tttgtgtact gtggctccgc gattcccaaa
     9361 gtgttcggtg ctatcaccaa taacttccag ttcaaaggga tcgacctgtc gttcatgttc
     9421 tattattctt atggttccaa aatatcggac tatacatata aagaacgtat catgaaccgt
     9481 ccgggtgtcg gtgtgataca ggagttggtt gaggacagat ggcgtcagcc gggcgatgcg
     9541 gatgtgctta tcccacgttg gtcgtacaac cagtatggcg cgacggtaaa atatgcagat
     9601 aacttcgtat tcgacaacca ctactggcgt ctgagaaacc tgacattagg ctatacgctg
     9661 cctaagagcc ttacccgcaa ggccctggta gaaaacctgc gtgtttatgt aaccggtaat
     9721 aacctgttga ctttcggtcc tgccaaaaaa cgctacacag accccgaaac aggtataatg
     9781 ggtaacagtt ataacggtaa tgctgaaacc gataacggta ttcagggttc gagaagactg
     9841 tatatggtcg gtattcaaat cacattgtaa acgtaaaaaa tgatatttat gaaacgattt
     9901 ataaatatat ccttcctgtc cctggttttt gctggtatgg ccctgaccgg atgtaacgac
     9961 gacctgacaa ccagctccta cgtgaaagta aacgatgaag atgtactggg gaatgtctcc
    10021 cagttggaaa aagtattgac ttcagcctat aagcagctgt attttaatac cgataaaggc
    10081 gaccgtgtgt atgccggtct tcccggattc cagatgtatg tcgatgcgag tggtgccgac
    10141 gtgatcagcc ataccaatat gggaggtgat caggtaacag cataccagta ttccaactca
    10201 aaaacacagg ctgacggaaa tgcctcaaaa atctggtcga tgtgctataa tgtgatcaac
    10261 cgtgccaata tcatcctgac caatgtggat gccgccgccg gtgatgaaac acagaaaaaa
    10321 catatcaaag gccaggcgtt ggcgatgcgt ggaatccagt atttccatct gatccagaat
    10381 taccagcaga cgtatgcgat agctaaaagc aagcgtgggg tgatcctgcg tacctcttcc
    10441 gatgatgaat cccataaagt tttttctact gtagaggaag tctataccca gattgtgtcc
    10501 gacctgacga cggctaaaac attgcttgcc gattataatc cggacgatat gtggctgatc
    10561 aactccaaaa tatgttcggg aatcctggcc cg
//
