LOCUS       c00019_gnlPro..        17026 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|IKMIAAII_19.
ACCESSION   c00019_gnlPro..
VERSION     c00019_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-05 13:30:38
            Original ID  :: gnl|Prokka|IKMIAAII_19
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 17026
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..17026
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[3540:7026]"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      3541..7026
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
     cand_cluster    1..17026
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /kind="single"
                     /product="Fumarate2succinate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..17026
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Fumarate2succinate"
                     /region_number="1"
                     /rules="(Succ_DH_flav_C and FAD_binding_2 and (Fer2_3 or
                     Fer4_7 or SucD_FumR))"
                     /tool="gutsmash"
     CDS             complement(180..764)
                     /locus_tag="ctg19_1"
                     /transl_table=11
                     /translation="MTTKLKDLFDTFLNIAASSQKLGINLIRVAILIIFVWIGGLKFYN
                     YEAEGIVPFVANSPFMSFFYAKSAPEYKEYKLKEGEFNEAKHQWHVENNTYIFSHGLGI
                     MIMAIGILTFLGIFSPKIGLIGSGLAIIMTLGTLSFLVTTPEVWVPDLGSGEHGFPLLT
                     GAGRLVIKDTAIIAGAIVVLSDCAQRILKKK"
     CDS             complement(942..2051)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Radical_SAM"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg19_2"
                     /sec_met_domain="Radical_SAM (E-value: 1.6e-09, bitscore:
                     29.4, seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MCFYAEDMDKKEKDLTFEEIKTISETAGQFNRLWVSGGEPTLREE
                     LPEIIEMFYKNNEIKDVNIPTNGLKPDRIVAWVKQIRQNCPELNINLSLSLDGFGDTHD
                     IQRGVPGNFYKAMGTLKLIEKNFADDGRVLKNLATVITKYNENEVEDLMIWMLGRFHLS
                     NHIIEAARGMTRDDGVKVLTEPTLRALQDKVVPIYNVYGERMAEETGGFRKPIARFFYL
                     GFIRTLYNVRATNIDHPTPWGMDCTAGETTLVIDYDGRFRACELREPLGNVKDYNCNIA
                     KIMESDAMKQEIAAIGHGDKANCWCTHGCWITSSLVFNPRKMITQVYKGYREMKKLNRP
                     LNISEELLQSIERKYALDEQKLVELGVRN"
     CDS             2367..3242
                     /locus_tag="ctg19_3"
                     /transl_table=11
                     /translation="LYIQLSVYKSMEDNIPKFDLPVDFIVGNSITGEILNQYGRFPCKI
                     KAGIFVLCVQGTVHATVNLTEFTIRKNDFITLPPGCFIQIHEVSDDVKLCFAGFSSVFV
                     SHINYIKTITNYLPVIFDSPIMPLPEHISLLYQQAFDLLINAYSMPKTIENKEIIKAIF
                     TIFMQGVIELYRNHTPYSNAPMTRNMEICREFVQLAMENYTKEHSVSYYAKRLNITLQH
                     FCYVIKKVSGRTALDILSNIIIMDAKAQLKSTDMPVKKIAFALGFDNLSFFNKYFRQHV
                     GMTPQEYRES"
     CDS             complement(3541..4296)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Fer2_3"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_8"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg19_4"
                     /sec_met_domain="Fer2_3 (E-value: 2e-26, bitscore: 83.2,
                     seeds: 38, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_8 (E-value: 6.7e-12, bitscore: 36.8,
                     seeds: 153, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 7.1e-06, bitscore: 17.5,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDKDIKVTLKVWRQKSPKDKGQFETYQIDKINQSVSFLEMLDILN
                     ERLVSEGKEPIVFDHDCREGICGMCSLYVNGHPHGPATGATTCQLYMRRFNDGETITIE
                     PWRSAGFPVIRDLMVDRYAYDKIIQAGGFVSVNTGGVPDANSIAIPRADAEMAMDAAAC
                     IGCGACAAACKNGSAMLFVSAKVSQLALLPQGKVEAARRAKAMVAKMDELGFGNCTNTR
                     ACEMECPKNISVSNIARLNREFICAKLQD"
     CDS             complement(4324..6267)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: FAD_binding_2"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Succ_DH_flav_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1027:FAD binding domain (Score: 195.7; E-value:
                     4.7e-60)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg19_5"
                     /sec_met_domain="FAD_binding_2 (E-value: 2.3e-60, bitscore:
                     195.7, seeds: 62, tool: rule-based-clusters)"
                     /sec_met_domain="Succ_DH_flav_C (E-value: 2.3e-38,
                     bitscore: 122.1, seeds: 739, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTQIDSKIPQGPLAEKWKNYKDHQKLVNPANKRRLDVIVVGTGLA
                     GASAAASLAEMGFNVLNFCIQDSPRRAHSIAAQGGINAAKNYQNDGDSVYRLFYDTIKG
                     GDYRAREANVYRLAEVSNSIIDQCVAQGVPFAREYGGLLDNRSFGGAQVSRTFYARGQT
                     GQQLLLGAYSALSRMIGLNKVKMYTRHEMLDVVKVDGRARGIIARNLITGQIERFSAHA
                     VVVATGGYVNTFFLSTNAMASNGSAAWQCYKKGAYFANPCMVQIHPTCVPVKGDYQSKL
                     TLMSESLRNDGRIWVPKKLEDAKALQAGTKKGKDIPEADRDYYLERRYPAFGNLVPRDV
                     ASRAAKERCDAGFGVNNTGLAVFLDFSDAINRLGKDVVKAKYGNLFDMYEEITNDDPYE
                     TPMMIYPALHYSMGGLWVDYELMTSIPGLFAIGEANFSDHGANRLGASALMQGLADGYF
                     VLPYTIQNYLSDQIQVPRFSTDLPEFAEAEKGIKDRIKKLMSIKGKESVDSIHKKLGHI
                     MWEHVGMARDAKGLQEAIQMLKELKKEFWSNVYIPGEADNLNVELDKALRLADFIEIGT
                     LMAHDALDRAESCGGHFRTEHQTEEGEALRHDDKFMYVSCWEYQGEDKDPVMLKEDLNY
                     QFVVPQTRNYKK"
     CDS             complement(6301..7026)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: SucD_FumR"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg19_6"
                     /sec_met_domain="SucD_FumR (E-value: 5.2e-76, bitscore:
                     245.5, seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MWLLNSSIGKKLIMSVSGLFLVLFLLFHLSMNVAAAFSGEAYNMI
                     CSLLGANWYAVAATLVLAAGVVIHFVYAVLLTLQNRKARGNDRYAINARPKGVEWASQN
                     MLVLGIIIILFMVLHFSQFWYKMMFAELLGNHMVTLCDGTTTVSPQDGAAFINYYFQGN
                     ILNTVLYLVWYVALWFHLTHGFWSAIQTIGWSNTIWMNRWICISKIVATVICVVFAIIT
                     IVFYLNGVGGDYVAVCAGH"
     CDS             7265..8407
                     /locus_tag="ctg19_7"
                     /transl_table=11
                     /translation="MLQRKMLSFLFMMIFIPSVRAQWKDSTRFINKEHEFETTYNKISE
                     NKVYQMLRVPVPLFAISAITYGQGDKFRTLRNTHTPNFHYRYDDFLQYTPLLAVYGMKL
                     GGVESRSSWPRMIVSNAFSATIMAATVNSMKYTIKRERPDGSKNNSFPSGHTATAFMAA
                     TIMHREYGLTHSPLYSIGGYTVATATAFSRQLNNRHWLSDVLAGAGIGILSTELGYFLA
                     DLIFKDKGLNLPDKLRESAPKGGRPSFLEFAVGYSIINGSIEVGKNIRLSSPGATNVSV
                     KGGYFFNPYFGIGGEITALASPMAFDMSLYTGTTPSTKYDITRIHADPTGVFTFTAGPY
                     FSLPVASKLLLGTKFQAGYSYLVKNEVEMDLQEKHPHAEP"
     CDS             8422..8661
                     /locus_tag="ctg19_8"
                     /transl_table=11
                     /translation="MKGNGSSNYVLRTGISATGIVSRNLGIRMFVDYDYTFLKAPYEIL
                     TSLRDSQPVYGESHLSKHKIHYFTIGATVTALFW"
     CDS             complement(8665..10488)
                     /locus_tag="ctg19_9"
                     /transl_table=11
                     /translation="MNKTILLVVFCFSLFVSGYSQGIRFDSYPSHPRLLVKKGEEQKIK
                     SDLALNPEMLRLHNYLLGQCDDLITTPVLAYKKEGKRLLAVSREALRRIFYLSYAYRMT
                     GEDKYRLRAEQEMIAVCSFTDWNPSHFLDTGEMTMAVAIGYDWLFDRLSPDARRLVQEA
                     ILNKGFAPSRDKRYNWFLRATNNWNQVCNAGLVYGALAVLEDHLEEAREIIERALSTVG
                     STLKGYGPDGAYPEGYNYWGYGTTFQVLLNAALESALGTDGGLSSAEGFLASARFMQFM
                     TGTTGKCFNFSDSRETVFALPAMYWFADKLQDPTLLWNEKDMLSRAELSFSDEESRFLP
                     LIPIYGSQYKMNELVPPAMKLWAANGQTPVVLVRTGWENGEGFYLGIKGGTASTSHAHM
                     DAGSFVFDALGVRWVQDLGMQEYYSLEKENVDLWNMSQNGQRWNVFRYNNLAHNTLTVN
                     GKYHDVKGFVPVTNIYSEAHKLGASLNMTDLFGGELENAVREVALINEKYLSVIDRVKA
                     GSQPATVRWTIVTGAIPRVLDSHMVELTKDGKCMQLIVDSPSVTSVSVLDNVSKNSYDA
                     SNEGTCRIVFDVSLESGQESDIKVRLVPAAD"
     CDS             11219..11695
                     /locus_tag="ctg19_10"
                     /transl_table=11
                     /translation="MKTLVHTEKEHIEEIIRSCDVCFVGLADTDGTPYVIPMNFGYRNG
                     VIYLHSAQEGRSISILERNPKVCITFSTDHDLVFQHPEVACSYRMRSKSVIAWGKVRFE
                     EDFDKKTEALDIIMKQYSDKEFRYSDPAVKNVKIWLVDLDEVTCKEFGAPHKKY"
     CDS             11716..12186
                     /locus_tag="ctg19_11"
                     /transl_table=11
                     /translation="MKNLLAIFLMVFLFASCEGPMGPPGRDGEDGGITYWIFDKDIQVK
                     SSDWELVDNGNNEPFYMYEYRIADKDFDIYQDAYKEGLITCYMYLDHGEDKEAQTALPN
                     PVNRIDKENNIWTETYAAEYTKDGFIIFKVTFSDFFTDQRPPETHFKAVITY"
     CDS             12245..13144
                     /locus_tag="ctg19_12"
                     /transl_table=11
                     /translation="MGLQKHSKVLNETVEKLSDECSYKQLFHAYRDEEALPSGEVLEEI
                     IDLCRAILFPGYYGNARISTQTIRFHTGVNIEKLHELLSRQIYAGLCLADTSCTSCAEE
                     LIFSQAEKLSEAFISTLPEMRCLLATDAEAAYNGDPAAQNINEVIFCYPGFRAIGNYRI
                     AHQLYKLGVPFIPRMITEMAHSETGIDIHPGAQIGHYFSIDHGTGTVIGETSVIGNNVR
                     IFQGVSLAGEKLPPDENGNAIRGVPRHPILEDNVTVYSNATLLGKIRVGKGATICGNVW
                     ITGDVPPGAVITQNKVTK"
     CDS             13191..14768
                     /locus_tag="ctg19_13"
                     /transl_table=11
                     /translation="MVAKTLYGLEEILAGELLAIGANDIEIGRRMVSFTGDKEVLYRAN
                     FCCRTALRILKPIYHFKAKDADTVYKEVKKVVWENYMSLDKTFAIDSVIYSEDFNHSKF
                     VAYRTKDAIVDYFMEKHNKRPSVRVNNPDLYINIHISHNDCTLSIDSSGESLHKRGYRV
                     EQTEAPLNEVLAAGMILKTGWKGESNFVDPMCGSGTLLIEAAMIALNIAPGIHRKEFAF
                     EKWIDFDQELFDRIYNDESQEREFTFKCYGSDINPAAIEIAQKNIRSAGLAKYVELKTM
                     PFQQYTEAPQPGILVTNPPYGERISSRDLLGLYNMIGERVKHVFTGYKVWILSYKDECF
                     DKIGLRPSERMKLINGSLDCEYRCYEIFEGKNKDYKKALNEEGAERTEDSASRPRPSFP
                     EKRYDTRPAGRPNFKTDRMDRPDRRFAAAHSEDENERTSAAPGKRFFGEERGDGRPARK
                     QFGGERGERPVRPILHKAGEKRPVKMRYKDEDDRFSKNRKNFGDRKRGEGRPFKKPFRR
                     EDNDDFED"
     CDS             14752..16968
                     /locus_tag="ctg19_14"
                     /transl_table=11
                     /translation="MTLKIKHFLVLCVFALSTSMTLMAQDKQLTLHDLLPGGKTHNKFV
                     PASLKQLQWCGDTYLYVKGDSMICGVPEKKEQVAFTRSRLNEALSAAGLPTVGSLPGFS
                     VPYKDQPVLAFTSKGHRLHYNFAENKIIGNYQLDSKGSNYNFCPANNCLAFTVGNNIQI
                     LSPENQTSIVTRETKDGIVCGQAVHQREFGISKGLFWSPAGSALAFYRMDESMVTDYPI
                     VNIDARQAKAEPVKYPMAGMKSHEVTVGVYNLSTGETVWLETGTPKEKFLTNIAWSPDE
                     KSIYIAELNREQNEMNLVRYSALTGKKEAVLFTETNEHYVEPQYPVLFLPNDPGKFIWQ
                     SQKDGYNHLYLYDTTGKQLKQLTQGEWVVTQVIGFDAKGENLFITSTQPHIRSSFNYGT
                     PMNVNGWKLNLKKGETSLLTPNAALESVHNLSVSASGKYAIDSYDAPKIPRIINLIRTK
                     DGKEIKNLLTARDPYKGYTLPEIEAGTIKSADGTTDLHFRLVKPVGLDENKKYPTIVYV
                     YGGPHSQLVTGGWQNGVRGWDIYMAQRGYVVFTVDNRGTSNRGFAFESVIHRNLGVNEM
                     ADQMKGVEYLKSLPYVDADRIGVHGWSYGGFMTTNLILTHPDVFKVGVAGGPVIDWSNY
                     EIMYGERYMDRPQDNPEGYKNANLKLKAGNLKGHLLQIHGDIDPVVVWQHSLGFLKACV
                     DADTYPDYFVYPRHEHNVTGKDRPHLYEKITRYFDDYLKNTNKE"
ORIGIN
        1 ctttgttaac cttaaatcta atactattat gaaaaaacca cgatgcaaat atactgctta
       61 atccaaacct gtcaagaggt tttatgctaa atggtgtttc atacactata agaaaagcta
      121 acaaggttca atatgtttgt tttttgcttc caaagtgtta aaataaacac tttttgttcc
      181 tatttcttct ttaatatacg ttgtgcacag tcggacaata ccacgatcgc tccggctatg
      241 attgccgtat cttttattac cagccgacct gctccggtca gtaaggggaa accatgttct
      301 ccgcttccca aatcgggcac ccatacttca ggtgttgtca ccaggaatga aagcgtaccc
      361 aatgtcatta tgatcgccag tccggaacct atcaagccaa ttttcggaga aaagataccc
      421 aggaaagtca ggataccgat cgccatgatc ataatgccta gtccatgtga aaaaatatag
      481 gtattgtttt ctacatgcca ctgatgcttg gcttcattga attcaccttc tttcaactta
      541 tattctttgt attccggtgc actctttgca tagaaaaagc tcataaacgg actgtttgcc
      601 acaaaaggaa cgatcccttc cgcttcataa ttatagaatt tcagcccgcc gatccatacg
      661 aatataatca ggatagctac gcggatcagg ttaataccca gtttctgtga agaagctgca
      721 atgttcagaa atgtgtcgaa taaatctttt aatttagtag tcatgtcttt ctttgtttat
      781 cagtttaact tatgatgcaa agatccgaca tttttcccct atgggaaatg gcaattctac
      841 cagataattt gacaattatt cccttaaaca caataaagcc ggttaacaga ggtatatttc
      901 ccgtcaaccg gctttataaa tgatccgtta tcggaactat tttaattacg aacccccagc
      961 tccaccagtt tctgttcgtc caaggcatat ttgcgttcga tgctctgcaa aagctcttca
     1021 ctgatattca gaggacggtt cagcttcttc atctcccggt atcctttata gacctgcgtg
     1081 atcatcttgc ggggattgaa aacaagcgat gaagtgatcc aacacccatg cgtacaccag
     1141 cagttagcct tgtcaccatg accgatagcg gcaatctcct gtttcatggc atcgctctcc
     1201 ataatctttg cgatattgca attataatcc tttacattac cgagcggttc gcgaagttca
     1261 caggcacgga aacgaccgtc atagtctatt accagtgttg tttcgccggc cgtacaatcc
     1321 ataccccagg gggtcggatg atcgatattg gtcgcacgta cattatataa tgtacgtatg
     1381 aaacccaggt agaagaaacg ggcgataggt tttctgaacc caccggtttc ctccgccata
     1441 cgctccccat atacattata aataggaaca accttatcct gcaaggcgcg taaagtaggc
     1501 tcggtaagaa ccttcactcc gtcgtcgcgg gtcatgccgc gtgcagcttc gataatatga
     1561 ttggaaagat ggaaacgtcc cagcatccat atcatcagat cctcgacctc attctcgtta
     1621 tatttggtga ttacggtggc caggtttttc aacaccctgc catcgtcagc aaagtttttt
     1681 tcaatcagct tcagtgtccc catcgctttg tagaaattgc cgggaacgcc gcgctgtata
     1741 tcatgcgtat caccgaaacc gtccaaagaa aggctcaggt tgatattcag ttccggacaa
     1801 ttctggcgga tctgttttac ccaggcgacg atccggtcag gcttcaatcc gttggtaggg
     1861 atattcacgt cctttatctc gttattcttg tagaacatct ctataatttc aggtaactcc
     1921 tcacgcagtg tcggttcacc gccggatacc cacaaacggt tgaactgccc ggctgtttcg
     1981 gagattgtct tgatttcttc aaaagtcagg tctttctcct ttttatccat gtcttctgca
     2041 tagaaacaca ttttacattt agcattacac cgtcctgtga caaacaggaa aacagattct
     2101 aattttctgt ttgtgctcat tgtcctgaaa gagctctttg ttcttttcgt actcattgtt
     2161 attatcgatt agatttctct attagtatta gctcccatat cttatttagc agatagacaa
     2221 atatatacca tcccaacaaa tctatcagca agacttgaaa acattcgcaa atttcaacta
     2281 ttatacagca caaaacaatc tccatttgtg ggattcgatg ttctatattt aagattatcg
     2341 actaacttgt ctcaaaaaaa ctatctttgt acattcaatt aagtgtatat aaaagtatgg
     2401 aagacaatat tcctaaattc gacctccccg tagattttat tgtaggaaac agtattacag
     2461 gtgaaatact gaaccaatac ggacgtttcc cgtgcaagat caaggcaggc atattcgtgc
     2521 tttgcgtaca agggacagtc cacgcgactg taaacttaac tgagtttacc atccggaaga
     2581 acgactttat caccttgccc ccgggttgct tcattcagat acatgaggtt tccgatgatg
     2641 taaaactgtg ttttgcaggc ttttcttccg tattcgtcag ccatatcaat tatataaaga
     2701 cgattacgaa ctatctgcct gtcatattcg acagtccgat catgcctctg ccggagcata
     2761 tatccttact ctaccaacag gctttcgact tgctgatcaa tgcttattcc atgcctaaaa
     2821 ccatcgagaa caaggagatt atcaaggcta tctttactat cttcatgcaa ggggttattg
     2881 aattatacag aaatcatacg ccatatagca atgctcccat gacgcgtaat atggaaatat
     2941 gccgggagtt cgtacaactg gcgatggaaa actacacgaa agagcatagc gtgtcttatt
     3001 acgccaaaag gctcaacatc accttgcagc atttctgtta tgtgataaaa aaggtcagcg
     3061 gacggactgc attggatatc ctgagcaata tcatcattat ggatgccaaa gcgcagctta
     3121 aatcgaccga tatgccggtc aagaaaattg cattcgccct gggttttgac aacctttcgt
     3181 tcttcaacaa atatttccgg caacatgtag gaatgacccc gcaggaatac agggaaagct
     3241 aaaaaaaggg atatgccgga cgcaaacccc tataaacaat taaagcctgt ctcacgacaa
     3301 gccctaacca actttgttaa ccttaaatct aatactatta tgaaaaaacc acagtacaaa
     3361 gatacaggta ttctccaact tgtcaatagt taaaatgcta attagtgttg tatagcatat
     3421 aagaaacact aacaacattc aagatattta tctatgactt cagaaatgtt aaaatagggg
     3481 caaaaaagaa gaggcgctgc cataagcaac gcctctccgg acatacatat ataatgtata
     3541 ttagtcttgc aatttagcac aaatgaactc gcggttcaaa cgagcgatgt tgctgacaga
     3601 gatgttcttc ggacattcca tttcgcaagc acgcgtgttg gtacagttac cgaagcccag
     3661 ttcgtccatc ttggcaacca ttgctttcgc acgacgagca gcttctacct taccctgagg
     3721 caacagagcc aactggctaa cctttgcaga aacgaacaac atagccgaac cgttcttaca
     3781 agcagcagca caagcaccgc aaccgataca tgcagcagca tccatagcca tttcagcatc
     3841 tgcacgagga atagcgattg aattggcatc aggtacacca cctgtgttca ctgatacgaa
     3901 accacctgcc tggataattt tatcgtaagc ataacggtct accatcaagt cgcggattac
     3961 cgggaaaccg gcagaacgcc acggttcgat tgtaatagtt tcgccatcat tgaagcgacg
     4021 catataaagc tggcaagtag ttgcgccggt tgcaggtccg tgcggatgtc cgtttacata
     4081 caaagaacac ataccgcaga taccttcacg acagtcgtga tcgaatacga tcggctcttt
     4141 accttcactg accaaacgtt cattcaaaat gtctaacatt tccaggaaag aaacactctg
     4201 attgattttg tctatttggt aagtctcaaa ttgtccttta tctttcggac ttttctgacg
     4261 ccaaacttta agtgttactt ttatatcttt atccatgatt ctaatttttg tgattgatga
     4321 ttattacttc ttgtagttac gtgtttgagg aacaacgaac tgatagttca aatcttcctt
     4381 cagcataacc ggatctttgt cttcaccctg gtattcccaa caagatacgt acatgaactt
     4441 atcgtcatga cgcagggctt cgccttcctc ggtctggtgc tctgtacgga agtgtcctcc
     4501 acaagattcg gcacggtcca atgcatcgtg tgccatcaat gtaccaatct caataaagtc
     4561 agccaaacgc aatgccttat ccaactctac gttcaggtta tcggcttcac ccggaatata
     4621 tacattactc cagaactctt tcttcagctc tttcaacatc tggatcgctt cctgcaaacc
     4681 ttttgcatca cgtgccatac ctacatgttc ccacatgata tgacccagtt tcttatgaat
     4741 agaatctacc gactctttac ccttgatact catcaatttc ttgatgcggt ctttgatccc
     4801 cttttcagct tctgcaaact caggcaggtc ggtactgaaa cgcggaacct ggatctggtc
     4861 tgacagatag ttctggattg tataaggcaa tacaaagtag ccatcggcca atccctgcat
     4921 caacgcagaa gcacccagac ggttagctcc gtggtcagag aagttagctt caccgatagc
     4981 gaacagaccc ggaatagaag tcatcaattc atagtcaacc cacagaccac ccatcgagta
     5041 gtgcaatgca ggataaatca tcatcggagt ttcgtatgga tcgtcgttgg taatttcttc
     5101 gtacatgtcg aacaagttac catatttagc ttttacaaca tctttaccca gacggttaat
     5161 ggcgtcggag aagtcgagga acacggccag acctgtgttg ttcacaccga aaccggcgtc
     5221 gcaacgttct ttagcggcac gtgaagccac gtcacgcgga accaggttac cgaatgccgg
     5281 ataacggcgt tccagatagt agtcgcggtc tgcttcagga atgtctttcc ctttcttagt
     5341 tccggcctgt aatgcttttg catcttccag tttcttcgga acccagatac gaccgtcgtt
     5401 acgcaatgat tcagacatca aagtcagctt agactggtag tcacctttca ccggtacaca
     5461 agtcgggtgg atctgcacca tacaagggtt agcgaagtaa gcacctttct tgtagcactg
     5521 ccatgcagca gaaccgttgg aagccattgc gttagtagac aggaagaaag tatttacata
     5581 accacctgtt gccaccacta ctgcgtgagc agaaaaacgt tcgatctgac ctgtgatcag
     5641 gttacgtgcg atgataccgc gggcacggcc atccaccttc acaacgtcca gcatttcgtg
     5701 gcgggtatac atctttactt tgttcaaacc gatcatacgg ctcaaagcag agtaagcacc
     5761 cagcaacaac tgctgtccgg tctgaccgcg ggcatagaac gtacgggata cctgagcacc
     5821 accgaatgaa cggttatcca gcagaccacc gtattcgcga gcgaaaggaa caccctgtgc
     5881 tacgcactgg tcgataatag agttggaaac ttcagccaga cgataaacgt ttgcttcgcg
     5941 ggcacgatag tcaccacctt tgattgtatc gtagaacaga cggtaaacag agtcaccatc
     6001 attctgataa ttctttgcag cattgatacc accctgtgca gcgattgagt gtgcgcgacg
     6061 gggagaatcc tggatacaga agttcaatac gttgaatccc atttctgcca gagaggcagc
     6121 agcagaagca ccggccagac cagtaccaac tacaatcacg tccagacgac gtttgttcgc
     6181 ggggttcacc agtttctgat gatctttata atttttccac ttctcagcca acgggccctg
     6241 agggatttta gaatctattt gagtcataat gatttatttt caatattgtt acaccttaaa
     6301 ttaatgtcct gcacaaacag ctacatagtc accacctaca ccattcaggt agaaaacgat
     6361 agtaatgata gcaaacacta cgcaaataac ggttgctaca atcttggaaa tgcagatcca
     6421 acggttcatc cagatcgtgt tactccaacc gatagtctga atagcgctcc agaacccgtg
     6481 agtcaggtgg aaccacaaag ctacgtacca taccagatac agcactgtat tcaggatatt
     6541 accctggaaa tagtagttga taaacgctgc accgtcctga ggagatacgg ttgttgttcc
     6601 gtcgcaaagt gttaccatgt gattgcctag gagttcggcg aacatcatct tataccagaa
     6661 ctggctgaag tgcaacacca tgaacaggat aatgataata cccagtacca gcatgttctg
     6721 agatgcccat tccacacctt tcggacgagc gttaattgca taacggtcgt taccgcgagc
     6781 cttacggttt tgcagtgtaa ggagaacagc atacacaaag tgaatcacaa cgcctgctgc
     6841 cagcaccaat gttgctgcca cggcatacca atttgctccc aacaatgaac aaatcatgtt
     6901 ataggcttct cccgagaaag cagccgccac attcattgac aagtggaaca ataagaacaa
     6961 aacaagaaaa aggcctgata cactcattat cagcttcttc ccgatagaag aattaagtaa
     7021 ccacataaga taataattta agttatttaa ttgtttttag aaattcatat caatatactc
     7081 aattatcagg caaaggtatg ctaaatacac gtatcacgca aacgattaaa gaaatatttc
     7141 gccaatcaaa cctatacatt tcaggaggga caaacggtaa atcctattca ataaataaat
     7201 taacaaaaat gtaaccagta ctaaccggca tttttatatc ttcgtggcat aatcagggga
     7261 tcgtatgtta caacgtaaaa tgctgagctt cttatttatg atgattttta taccgtctgt
     7321 tcgtgctcag tggaaagata gtacgagatt cataaataaa gaacatgaat ttgaaaccac
     7381 ttacaacaaa atatcagaga ataaggtata ccagatgcta cgtgtccctg ttcctctttt
     7441 cgccatttca gccataacat atgggcaggg cgataaattc cggacattgc gcaatacgca
     7501 tacgcccaac ttccattaca gatacgatga ttttctgcaa tatactccgt tgcttgctgt
     7561 ttacgggatg aagctcggcg gtgtggaaag tcgtagttca tggccccgga tgatcgtatc
     7621 gaacgctttt tcggcaacga tcatggccgc taccgtcaac agcatgaaat atacgatcaa
     7681 acgcgaacgc cccgacggct caaagaacaa ctcattccct tcgggacaca cggcaaccgc
     7741 tttcatggct gctaccatca tgcaccggga atatggtctg acccacagcc cgttatatag
     7801 tatcggggga tatacagtcg ccacagccac cgctttcagc cggcaactga acaaccgcca
     7861 ctggctgagc gacgtactgg ccggggccgg tatcggcatc ttatccacag agttagggta
     7921 ttttctggca gacctgatct tcaaggacaa aggcttgaat ctccctgaca agctcaggga
     7981 gtctgccccc aaaggagggc gcccttcttt cctggagttc gccgtaggat acagtatcat
     8041 caacggaagt atcgaggtag gtaaaaatat acgcctgagc tcgccgggag caaccaatgt
     8101 cagcgtaaaa ggcggttact tcttcaatcc ttatttcggt atcggcggcg aaataacagc
     8161 gctggcaagc ccgatggcat tcgacatgtc gctttataca ggaacaaccc cttcaaccaa
     8221 atatgacatc acccgcatcc atgccgatcc gaccggtgtt tttactttta cggcagggcc
     8281 ttatttctcg ttacctgtag ccagtaaatt gcttttagga acaaagttcc aggccggata
     8341 ttcctatctg gtgaaaaatg aagtggaaat ggacttacag gaaaagcacc cccatgcgga
     8401 accataaata atattgcttt tatgaaaggc aacggtagca gcaactatgt tttacgcaca
     8461 ggcatttcag cgaccggaat tgtcagccgc aacctgggta tccgtatgtt cgtagattac
     8521 gattatacgt tcctgaaagc accttacgaa atcttaacca gcctcagaga cagccaacca
     8581 gtctacggcg agagccattt aagcaagcac aaaatacact attttacaat aggggcaacc
     8641 gtaacggcgc tgttctggta attatcagtc agcagcagga accagccgga ctttgatatc
     8701 gctctcctgc ccgctttcca gacttacatc gaaaacgata cggcaggttc cctcattgga
     8761 agcatcatag ctattcttcg atacattatc aaggacggac acagaagtta cggatggact
     8821 atcgacgatc agttgcatac atttgccgtc ttttgtcagt tccaccatat gactgtccaa
     8881 tacacgggga atggccccgg ttacaatcgt ccatctgaca gttgccggct gactgccggc
     8941 ttttacacga tcaatcaccg acagatattt ttcattgatc agagcaactt cacggacggc
     9001 attttccaat tctccgccga acaagtccgt catattcaga gaagctccga gtttatgcgc
     9061 ttccgaatag atatttgtca caggtacaaa accttttaca tcatggtatt taccgtttac
     9121 agtcagtgta ttatgcgcca ggttattata acggaacaca ttccagcgct gcccgttctg
     9181 cgacatattc cataaatcta cattttcctt ttccagcgaa taatattcct gcatccccag
     9241 gtcctgcacc cagcgaacac ccaaagcatc gaacacaaac gatccggcat ccatatgggc
     9301 atggctggtc gaagccgttc ctccttttat tcccagatag aaaccttctc cattctccca
     9361 tcccgtacgg accagcacga caggcgtctg tccgttagcc gcccacaatt tcatggcagg
     9421 aggcaccagt tcattcattt tatattgtga accataaatc ggtatcaacg gaaggaaacg
     9481 gctctcctca tccgaaaaag acaactccgc ccgactcaac atatcctttt cattccaaag
     9541 cagtgtaggg tcttgcagct tgtcggcaaa ccagtacata gccggcaaag caaaaacagt
     9601 ctcacgggaa tcgctgaagt taaagcattt accggtcgtt ccggtcataa actgcataaa
     9661 acgggcagaa gccagaaaac cttcagccga agagagaccg ccgtcagtcc ccagggcgga
     9721 ttccaacgct gcattcaaaa gaacctggaa ggtagtcccg tatccccaat aattatatcc
     9781 ttcgggataa gcgccatcgg gaccatagcc cttcaaagtc gagccgactg tagacaaagc
     9841 acgttcaatg atttcacggg cctcttccag atgatcttcc aacacagcca gcgcaccgta
     9901 aaccagtccg gcattacaga cctggttcca gttattggtc gctctcagaa accagttata
     9961 tcttttatcc ctcgacgggg caaaaccttt attcagaatc gcctcctgca ccagcctccg
    10021 ggcatccgga gataaccgat cgaacaacca gtcataaccg attgcgacgg ccatagtcat
    10081 ttcgcccgta tccagaaaat gggacgggtt ccaatcggta aacgaacaca cggcaatcat
    10141 ctcctgctct gcccgcaaac gatacttatc ctctcctgtc atccggtaag catatgaaag
    10201 atagaagata cgccgcaagg cttcacgcga tacggccagc aaccgtttcc cttctttttt
    10261 atatgccagc acaggcgtcg tgatcagatc gtcgcattgc ccaagtagat agttatgcaa
    10321 ccggagcatc tccggattaa gagccagatc ggatttaatc ttttgctcct ctcctttctt
    10381 taccagcaac cggggatgag aagggtaaga atcaaagcgt attccctgtg aataccccga
    10441 aacgaacagg gaaaagcaaa acacaacaag caggatagtt ttattcatac aggtattata
    10501 tttaattgga gttacaaata taggaaatcg cttgaaaaag tgttttctta tccggaatcc
    10561 ttttaacaga caagaaaata ccattttgct acaatttaca acgattaaag atcattttgt
    10621 atattttttc cgcatatacg tatctgctat atttcacaaa acagtagaaa tagaagatcc
    10681 gaaaacacaa tatttaacac ttagcgtatt catatagatt ttcactcttc atcttaaaca
    10741 aattgtaatc tcgtttaaaa cgaatttttt ttcattttaa atgaaatgga gatttattgc
    10801 agatgaaaaa tttgttaatt ctgtccagaa aagttatttt aaacaggctt tgggacctca
    10861 aatcacatgc taaacaacac attttatctc cagaacgagt aaatatccaa accaaacccg
    10921 aacagcacat tcacatattt caaatgtact ttacgacatt tatcaacgac tatcacacat
    10981 catcaaacat aaagctacat ttattaatca acaattaaaa taaagacatt cgcaatcatc
    11041 ccgtagagcg aataaaaaca acaaacctga tttaggacgc gtacagctca ctgacagaag
    11101 ggctatttga cattttgaca cattgacgaa aacagtacat atataataaa gtcgcaaaag
    11161 taagtccgag aagttgaact tttttactat gtttgcaaaa gcataattaa aaatagtaat
    11221 gaagacactg gtacacacag agaaagaaca tatcgaggag attatccgta gttgcgatgt
    11281 ctgtttcgtc ggactggctg atacggatgg tacgccttac gttattccca tgaactttgg
    11341 ctatcggaac ggtgttatct atttacattc agcgcaggaa ggccgaagta tctcaatcct
    11401 ggaacgtaac ccgaaggttt gcatcacctt cagcaccgac catgatctgg tattccagca
    11461 tcccgaagtg gcttgcagct accgtatgcg ttccaaaagc gttatcgcat ggggtaaagt
    11521 gcggtttgaa gaagacttcg acaagaaaac ggaagcgctg gatataatta tgaaacagta
    11581 ttcggacaag gaattccgtt attccgaccc ggctgtgaaa aacgtaaaaa tatggctggt
    11641 agacctcgat gaagtaacat gcaaagagtt cggggcaccg cacaagaaat actaaacatt
    11701 taagagagtg aatatatgaa aaatctgtta gcaatatttt taatggtgtt cctgttcgct
    11761 tcatgcgaag gaccgatggg ccctccggga cgagacgggg aagatggcgg tataacctac
    11821 tggatatttg acaaggatat acaagttaag tcaagcgact gggaattagt cgacaatggt
    11881 aataacgaac ctttttacat gtatgagtac agaattgccg ataaagattt cgacatatat
    11941 caggatgctt ataaagaagg cttaattacc tgttacatgt atctggatca cggcgaagac
    12001 aaagaagcac aaactgcatt acccaaccct gtcaatcgaa tagataaaga gaataatatc
    12061 tggacggaaa cctatgcagc cgaatacacc aaagacggtt tcatcatctt caaagtgaca
    12121 ttctccgact tctttactga tcaacggccg ccggaaacgc atttcaaagc agttataacc
    12181 tattaaaagt acacatatat cagatattta atgtactttt gcccaaaata agactttcaa
    12241 aataatggga ttgcaaaagc atagcaaggt attgaatgaa acagtagaaa agctttcgga
    12301 cgaatgttca tacaaacaac tgtttcatgc ctaccgcgat gaagaggcat tgccttcagg
    12361 tgaagtactg gaggagatca ttgacttgtg ccgtgcaatc ctgtttcctg gctattacgg
    12421 gaatgcgcgg atcagtacac agacgatccg tttccatacc ggggtcaata ttgaaaagtt
    12481 gcacgagctg ctcagccgtc aaatctatgc gggcctttgc ctggccgaca ccagctgtac
    12541 ttcctgtgcg gaagagctga tcttcagcca ggcagaaaaa ctttccgaag cgttcatttc
    12601 cacactgccg gaaatgcgct gtctgcttgc caccgatgcc gaagccgcct acaacggtga
    12661 tccggcagca caaaacatca atgaagttat cttctgttac ccgggcttcc gggcaatagg
    12721 caattatcgt atagcgcacc agctttataa gttgggcgtt ccttttatac cccggatgat
    12781 caccgaaatg gctcattccg aaaccggtat cgacattcat ccgggagctc agataggaca
    12841 ttatttctct atcgaccacg gtacgggtac cgtgatcggc gaaaccagtg tgatcgggaa
    12901 taacgtacgc atcttccagg gtgtcagcct tgccggagag aagctaccac ccgatgagaa
    12961 cgggaacgcg atccgcggtg tcccccgcca tcccatcctg gaagacaatg tgaccgtcta
    13021 ctccaacgcg acgctattgg ggaaaatacg ggtcggcaaa ggtgccacga tatgcggcaa
    13081 cgtctggatc accggagatg ttccccccgg tgctgtcatt acacaaaata aagtaactaa
    13141 ataaatatct tttcttacaa cgcacgcaaa tgaataacga gacatttgaa atggtggcca
    13201 aaaccctgta cgggttagaa gaaatactgg ccggtgagtt attagctata ggcgccaacg
    13261 atatagaaat tggccgccgg atggtatcct tcacaggaga taaagaagtg ctttacagag
    13321 ccaacttctg ttgccgcacc gccttacgca tcctgaaacc gatctatcat ttcaaggcaa
    13381 aagatgccga tacggtttat aaggaagtga aaaaagtcgt atgggaaaac tatatgtcac
    13441 tggacaagac gttcgcgatc gactccgtga tctattcaga agatttcaat cactctaaat
    13501 tcgtggctta ccgtacaaaa gatgcgatcg ttgactactt tatggagaag cacaacaaac
    13561 gtccttccgt acgtgtgaac aatcccgact tatacatcaa tatacatatc tcgcacaacg
    13621 attgtacctt gtctatcgac agttcgggcg agagccttca caaacgcgga taccgcgtgg
    13681 aacagaccga agcaccgctg aacgaagtgc tggctgccgg tatgatcctg aagacaggct
    13741 ggaaaggcga atccaatttc gtcgacccga tgtgcggttc cggtacgctg ctgatcgaag
    13801 cggctatgat cgccctgaac atcgccccgg gtatccaccg caaggagttc gctttcgaga
    13861 aatggatcga cttcgaccag gaactgttcg accgcatcta taacgacgaa agccaggaac
    13921 gcgaattcac tttcaaatgc tacggttcgg atatcaaccc ggccgctatc gagatcgccc
    13981 agaagaatat ccgtagcgca ggcctagcca aatacgtcga actgaaaacg atgcctttcc
    14041 agcaatatac ggaagcaccg caaccgggta ttctggtaac caacccgcct tatggcgaac
    14101 gtatctcctc ccgcgacctg ctgggacttt ataatatgat cggcgaacgc gtcaaacatg
    14161 tgtttaccgg atataaagta tggatactca gctacaaaga cgaatgcttc gacaagatcg
    14221 gcctgcgtcc cagcgaacgg atgaagttga tcaacggctc gctcgactgc gaataccgtt
    14281 gttacgaaat atttgaagga aagaacaaag actataagaa agcattgaac gaggaaggcg
    14341 cggaaagaac ggaagattcc gcctcacgtc cgagaccctc attccctgaa aaaagatatg
    14401 acacccgtcc tgcaggtcgc ccgaacttca agaccgatcg catggatcgc cccgaccgtc
    14461 gttttgccgc ggctcacagt gaagacgaaa acgaacgtac atccgcagca ccgggaaaac
    14521 gtttcttcgg cgaagaacgc ggtgacggcc gtcctgcccg caaacagttc ggaggcgaac
    14581 gtggtgaacg cccggttcgt ccgattttgc acaaagccgg cgaaaaacgc cccgtcaaaa
    14641 tgcgttacaa agacgaagac gacaggttct ctaaaaacag aaagaacttc ggagacagaa
    14701 aacgcggaga aggccgtcca ttcaagaaac cattcagaag agaagacaac gatgactttg
    14761 aagattaaac acttcctggt tctttgcgtg ttcgctttat ctacatccat gacgctgatg
    14821 gcacaggaca aacaactcac attacacgac ctgcttccgg gagggaagac acacaataag
    14881 ttcgtcccgg ccagtctcaa acagctacaa tggtgtgggg acacttacct gtatgtcaaa
    14941 ggagacagta tgatatgcgg cgtacccgaa aagaaagagc aggttgcctt tacacgcagc
    15001 cgactcaatg aggcgctttc ggcagccgga cttccgacgg taggcagcct gcccggattt
    15061 tcggttccct ataaggacca gccggtactg gcttttacca gtaaaggcca ccgcctgcat
    15121 tacaattttg ccgaaaacaa gataattggc aattatcagc tggacagcaa aggatcgaac
    15181 tataacttct gtccggccaa taactgcctg gcattcacgg tggggaacaa catacagatt
    15241 ctttcaccgg agaatcagac gagtattgtt acacgtgaaa caaaagatgg aatcgtctgc
    15301 ggacaggcag tccatcaacg tgaattcggc atcagcaaag gactgttctg gtcaccggca
    15361 ggttccgctc tggctttcta ccggatggac gagagcatgg tcacagacta tcctatcgtc
    15421 aatatcgatg cccgccaggc aaaagccgaa ccggttaaat atccgatggc cggcatgaag
    15481 agccatgagg taacagtcgg tgtgtacaac ctctcgacag gcgaaaccgt ctggctggaa
    15541 accggaaccc cgaaagaaaa gttccttacc aacatcgcct ggagcccgga tgaaaagagt
    15601 atctatattg ccgaactgaa ccgcgaacag aatgagatga acctggttcg ctattctgcc
    15661 ctgactggca agaaagaagc cgtccttttc acagaaacga acgaacatta cgttgaaccg
    15721 caatatccgg tactcttcct cccgaacgat cccggcaaat tcatctggca aagccagaaa
    15781 gacggataca accacctgta tctgtatgac accaccggca aacaactaaa gcaactgaca
    15841 cagggagaat gggtagtcac ccaggtaatc ggtttcgacg ccaaaggcga gaacctgttt
    15901 atcacttcca cccaaccgca catacggagt tcgttcaatt acggcactcc gatgaatgta
    15961 aacggctgga agctgaatct aaagaagggg gagacatccc tgctgacacc gaatgccgcc
    16021 ctggaaagtg tgcataacct ttcggtcagc gcctccggca aatatgcgat cgacagttac
    16081 gacgctccga aaatcccgcg catcatcaac ctgatccgga ccaaagacgg caaggagatc
    16141 aaaaacctcc tgaccgcccg ggacccatac aaaggctaca cactgccgga aatagaagct
    16201 ggtaccataa aatctgccga cggtacaacc gacctgcatt tccgcctggt caaacctgtc
    16261 ggactggatg agaacaagaa atacccgacc atcgtctacg tctacggcgg cccccactca
    16321 caactggtaa cgggcggctg gcagaacggc gtaagaggct gggatatcta tatggcacaa
    16381 cgcggctacg tggttttcac ggtcgacaac cgcggcacat ctaaccgggg attcgctttc
    16441 gaaagcgtga tccaccgcaa cctgggtgtc aacgagatgg ccgaccagat gaaaggcgtg
    16501 gaatacctga aatcgcttcc ttacgtggat gccgaccgta tcggtgtgca cggatggagc
    16561 tacggcggct tcatgacgac caacctgatc ctgacgcatc ccgatgtttt caaagtcggt
    16621 gttgccggcg gtccggtgat cgactggagc aactacgaga tcatgtatgg agagcgttat
    16681 atggaccgtc cgcaggataa tccggaaggg tataagaacg ccaacctgaa gctgaaggca
    16741 ggcaacctga aaggccatct cctccagata cacggcgaca tcgacccggt agtggtatgg
    16801 caacatagcc tgggcttcct gaaagcctgc gtggatgcag atacctatcc cgattatttc
    16861 gtctaccccc gccacgagca caacgtgaca ggcaaagacc gcccgcatct ctacgagaag
    16921 ataacacggt atttcgatga ctacttgaaa aatacgaaca aagagtaact gtttcccctc
    16981 ttgagagggg aaacagttac catcagataa tataataaac ataacg
//
