LOCUS       c00001_gnlPro..        12280 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|PKCPBMCM_1.
ACCESSION   c00001_gnlPro..
VERSION     c00001_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-07 19:56:34
            Original ID  :: gnl|Prokka|PKCPBMCM_1
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 12280
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             1..1497
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: FAD_binding_2"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Succ_DH_flav_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1027:FAD binding domain (Score: 115.5; E-value:
                     1e-35)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_1"
                     /sec_met_domain="FAD_binding_2 (E-value: 2.3e-35, bitscore:
                     115.5, seeds: 62, tool: rule-based-clusters)"
                     /sec_met_domain="Succ_DH_flav_C (E-value: 6.5e-38,
                     bitscore: 122.8, seeds: 739, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="GAQVSRTFYARGQTGQQLLLGAYSALSRMIGLNKVKMYTRHEMLD
                     VVKVDGRARGIIARNLITGQIERFSAHAVVVATGGYVNTFFLSTNAMASNGSAAWQCYK
                     KGAYFANPCMVQIHPTCVPVKGDYQSKLTLMSESLRNDGRIWVPKKLEDAKALQAGTKK
                     GKDIPEADRDYYLERRYPAFGNLVPRDVASRAAKERCDAGFGVNNTGLAVFLDFSDAIN
                     RLGKDVVKAKYGNLFDMYEEITNDDPYETPMMIYPALHYSMGGLWVDYELMTSIPGLFA
                     IGEANFSDHGANRLGASALMQGLADGYFVLPYTIQNYLSDQIQVPRFSTDLPEFAEAEK
                     GIKDRIKKLMSIKGKESVDSIHKKLGHIMWEHVGMARDAKGLQEAIQMLKELKKEFWSN
                     VYIPGEADNLNVELDKALRLADFIEIGTLMAHDALDRAESCGGHFRTEHQTEEGEALRH
                     DDKFMYVSCWEYQGEDKDPVMLKEDLNYQFVVPQTRNYKK"
     protocluster    1..12280
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[0:2280]"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      1..2280
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
     cand_cluster    1..12280
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /kind="single"
                     /product="Fumarate2succinate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..12280
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Fumarate2succinate"
                     /region_number="1"
                     /rules="(Succ_DH_flav_C and FAD_binding_2 and (Fer2_3 or
                     Fer4_7 or SucD_FumR))"
                     /tool="gutsmash"
     CDS             1525..2280
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Fer2_3"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_8"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_2"
                     /sec_met_domain="Fer2_3 (E-value: 9.3e-26, bitscore: 83.2,
                     seeds: 38, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_8 (E-value: 3.1e-11, bitscore: 36.8,
                     seeds: 153, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 3.3e-05, bitscore: 17.5,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDKDIKVTLKVWRQKSPKDKGQFETYQIDKINQSVSFLEMLDILN
                     ERLVSEGKEPIVFDHDCREGICGMCSLYVNGHPHGPATGATTCQLYMRRFNDGETITIE
                     PWRSAGFPVIRDLMVDRYAYDKIIQAGGFVSVNTGGVPDANSIAIPRADAEMAMDAAAC
                     IGCGACAAACKNGSAMLFVSAKVSQLALLPQGKVEAARRAKAMVAKMDELGFGNCTNTR
                     ACEMECPKNISVSNIARLNREFICAKLQD"
     CDS             complement(2579..3424)
                     /locus_tag="ctg1_3"
                     /transl_table=11
                     /translation="MEDNIPKFDLPVDFIVGNSITGEILNQYGRFPCKIKAGIFVLCVQ
                     GTVHATVNLTEFTIRKNDFITLPPGCFIQIHEVSDDVKLCFAGFSSVFVSHINYIKTIT
                     NYLPVIFDSPIMPLPEHISLLYQQAFDLLINAYSMPKTIENKEIIKAIFTIFMQGVIEL
                     YRNHTPYSNAPMTRNMEICREFVQLAMENYTKEHSVSYYAKRLNITLQHFCYVIKKVSG
                     RTALDILSNIIIMDAKAQLKSTDMPVKKIAFALGFDNLSFFNKYFRQHVGMTPQEYRES
                     "
     CDS             3665..4879
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Radical_SAM"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_4"
                     /sec_met_domain="Radical_SAM (E-value: 1.9e-13, bitscore:
                     44.2, seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSTKRTKSSFRTMSTNRKLESVFLFVTGRCNAKCKMCFYAEDMDK
                     KEKDLTFEEIKTISETAGQFNRLWVSGGEPTLREELPEIIEMFYKNNEIKDVNIPTNGL
                     KPDRIVAWVKQIRQNCPELNINLSLSLDGFGDTHDIQRGVPGNFYKAMGTLKLIEKNFA
                     DDGRVLKNLATVITKYNENEVEDLMIWMLGRFHLSNHIIEAARGMTRDDGVKVLTEPTL
                     RALQDKVVPIYNVYGERMAEETGGFRKPIARFFYLGFIRTLYNVRATNIDHPTPWGMDC
                     TAGETTLVIDYDGRFRACELREPLGNVKDYDCNIAKIMESDAMKQEIAAIGHGDKANCW
                     CTHGCWITSSLVFNPRKMITQVYKGYREMKKLNRPLNISEELLQSIERKYALDEQKLVE
                     LGVRN"
     CDS             5057..5641
                     /locus_tag="ctg1_5"
                     /transl_table=11
                     /translation="MTTKLKDLFDTFLNIAASSQKLGINLIRVAILIIFVWIGGLKFYN
                     YEAEGIVPFVANSPFMSFFYAKSAPEYKEYKLKEGEFNEAKHQWHVENNTYIFSHGLGI
                     MIMAIGILTFLGIFSPKIGLIGSGLAIIMTLGTLSFLVTTPEVWVPDLGSGEHGFPLLT
                     GAGRLVIKDTAIIAGAIVVLSDCAQRILKKK"
     CDS             6047..6796
                     /locus_tag="ctg1_6"
                     /transl_table=11
                     /translation="MNLRKNLFWAIPFIVVGVVWIMRNTGMITDDLFHIIVSWQMLVMY
                     IGIGSISRRHYIGGLITFLVGAAFLLPRLGWMDSDWLQVYWPAAFVIVGLMLIFEPRKK
                     NSYHYNSRREDTGGEDIRGNAVAGKVKSDFINTDGYVESDNTFGYVEQIILDPVFKGAR
                     IRTVFGGTVLDLRKTKLDSAKTYIDIDCKFAGVEIYLPGDWAVNFHGSPIMGACEDKRF
                     NASMEMDKEHILVVRGIVMFGGIEFKS"
     CDS             6799..7605
                     /locus_tag="ctg1_7"
                     /transl_table=11
                     /translation="MQTHPFINSVLCRMAGVALAVVSCSISALLLYYYGHTGWLVAWLD
                     SLVSVGIFCVSGFLFWYVTGILRPLQAQIALAVGVLIISVTGGYMAGALVYPDRMDWFA
                     STIPFRILLGLLGWIILAQWYYIRWKELQMEIQEEQRKEENAPAETGVSSPEEEAILDR
                     ISVKDGSRIHLIHLEELLYIQASGDYVALFTTDGQYIKDQTMKYFESHLPANLFIRIHR
                     SCIVNSEQIMRVELFGKESYQVRLKTGVCLRASLTGYKLLKERLSL"
     CDS             complement(7583..7774)
                     /locus_tag="ctg1_8"
                     /transl_table=11
                     /translation="MKKPQYKDKPETSVCQVFYRQYMLSLSGIVAKNCFRTQNFIQYRQ
                     KLLILTVKTAKSIEKDVL"
     CDS             7906..9126
                     /locus_tag="ctg1_9"
                     /transl_table=11
                     /translation="MEYIGLHEDKISLADIIKYLSLLKGNMDELNLLEFKTIKGWLVYS
                     LSLVLLLCIPCVIILLITGLLSGNIDSGLLLAVSFIPFLFILPLTLLLTFINNYRKPKK
                     LRELMQTVLMRYEWDGPINQTGRLQLECRKDHFLFRTEVLRQMNPKGRNVSLIFISVPF
                     YVPIEKELIHAEDIIAYLKGKSLFVIEPDMACLGMSFKMFQKLDLREDIDQLIYVMKRF
                     SLRPGTLFKAQDITLKVPETLEIQALFIFGQKIDQRFLNWANLMLDAGFVSDNMKIMAE
                     QASLTLPQKELKKRVEVIFLEFNLYFSKETVLNNYLIFLILEEQEERRSVLEIIQCLAS
                     LYQSSRLPLLQEYDLLYKAKRALDETGEQNFWTADPPLTVDNVDTYILTYLTRRLADLI
                     ASREKDQ"
     CDS             9305..11509
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glyco_hydro_36C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glyco_hydro_36N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Melibiase"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_10"
                     /sec_met_domain="Glyco_hydro_36C (E-value: 2.4e-20,
                     bitscore: 66.0, seeds: 330, tool: rule-based-clusters)"
                     /sec_met_domain="Glyco_hydro_36N (E-value: 3.4e-48,
                     bitscore: 157.5, seeds: 284, tool: rule-based-clusters)"
                     /sec_met_domain="Melibiase (E-value: 1.4e-124, bitscore:
                     408.6, seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKALLLTVALLLGCVTVSSQDKDTGIITVSTNDLSMVFSISPDKK
                     VVYNYFGDKFQDVSPFLHKKYKEQPDNGIGYAPVIYPAYGGRFFLNPALKLTHDDGVQT
                     TELIYAAHQVKNIDNNRIETVIQLKDPLYPVFVNLNFTAYQKENVICQSVSISHQEKNK
                     LAVENIASAYLPLHADSYYLTHFHGAWASEMQLVEEQLTPGVKRVESKKGIRTTQSENS
                     SFLLSLNGPANEDMGEVYAGSLAWLGNYLSSFEIDECGLLHVMSGMNDFASTYNLEPGK
                     TLQTPEMVWTYSSTGKGQVSRNLHDWSRNYALAHGDQELPIVLNSWEGAYFDFNEKTIT
                     DMIDDAAAFGVEMFVLDDGWFGNKYPRNSDKVGLGDWQVNRKKLPRGIDYLAKHAVSKG
                     LKFGIWIEPEMVSPKSELAEKHPEWIVKSGKRDIIPMRNQWLLDLSNPEVQDFVVKTFD
                     EVIALSPDISYIKWDANRHVDNFGSEYLSKENQTHFWIDYTKGLYSVYERIRAKHPDVL
                     IQLCSSGGGRLDFGALKYHDEFWASDNTNSLDRIFIQYSTNLFFPAKATAAHVSTTPNH
                     QTGMMAPLKFRFDVAMTGRLGMELQPEDLTGDELPFAEQAIKNYKRIRPIVQFGDLYRL
                     KSPYDGTGWASHMYISKDKKESVFFAYSLKYHGRTTFFETRLKGLDPAKMYKITELNKA
                     GNSTFYGDGQVFPGDYLMKAGISLTIGNTYESTVLLITEQ"
ORIGIN
        1 ggtgctcagg tatcccgtac gttctatgcc cgcggtcaga ccggacagca gttgttgctg
       61 ggtgcttact ctgctttgag ccgtatgatc ggtttgaaca aagtaaagat gtatacccgc
      121 cacgaaatgc tggacgttgt gaaggtggat ggccgtgccc gcggtatcat cgcacgtaac
      181 ctgatcacag gtcagatcga acgtttttct gctcacgcag tagtggtggc aacaggtggt
      241 tatgtaaata ctttcttcct gtctactaac gcaatggctt ccaacggttc tgctgcatgg
      301 cagtgctaca agaaaggtgc ttacttcgct aacccttgta tggtgcagat ccacccgact
      361 tgtgtaccgg tgaaaggtga ctaccagtct aagctgactt tgatgtctga atcattgcgt
      421 aacgacggtc gtatctgggt tccgaagaaa ctggaagatg caaaagcatt acaggccgga
      481 actaagaaag ggaaagacat tcctgaagca gaccgcgact actatctgga acgccgttat
      541 ccggcattcg gtaacctggt tccgcgtgac gtggcttcac gtgccgctaa agaacgttgc
      601 gacgccggct tcggtgtgaa caacacaggt ctggccgtgt tcctcgactt ctccgacgcc
      661 atcaaccgtc tgggtaaaga tgttgtaaaa gctaaatatg gtaacttgtt cgacatgtac
      721 gaagaaatta ccaacgacga tccatacgaa actccgatga tgatttatcc tgcattgcac
      781 tactcgatgg gtggtctgtg ggttgactat gaattgatga cttctattcc gggtctgttc
      841 gctatcggtg aagctaactt ctctgaccac ggagctaacc gtctgggtgc ttctgcgttg
      901 atgcagggat tggccgatgg ctactttgta ttgccttata caattcagaa ctatctgtca
      961 gaccagatcc aggttccacg tttcagcacc gacctgcctg agtttgcaga agctgaaaag
     1021 gggatcaaag accgcatcaa gaaattgatg agtatcaagg gtaaagagtc ggtagattct
     1081 atccataaga aactgggtca tatcatgtgg gaacatgtag gtatggcacg tgatgcaaaa
     1141 ggtttgcagg aagcgatcca gatgttgaaa gagctgaaga aagagttctg gagtaatgta
     1201 tatattccgg gtgaagccga taacctgaac gtagagttgg ataaggcatt gcgtttggct
     1261 gactttattg agattggtac attgatggca cacgatgcat tggaccgtgc cgaatcttgt
     1321 ggaggacact tccgtacaga gcaccagacc gaggaaggcg aagccctgcg tcatgacgat
     1381 aagttcatgt acgtatcttg ttgggaatac cagggtgaag acaaagatcc ggttatgctg
     1441 aaggaagatt tgaactatca gttcgttgtt cctcaaacac gtaactacaa gaagtaataa
     1501 tcatcaatca caaaaattag aatcatggat aaagatataa aagtaacact taaagtttgg
     1561 cgtcagaaaa gtccgaaaga taaaggacaa tttgagactt accaaataga caaaatcaat
     1621 cagagtgttt ctttcctgga aatgttagac attttgaatg aacgtttggt cagtgaaggt
     1681 aaagagccga tcgtattcga tcacgactgt cgtgaaggta tctgcggtat gtgttctttg
     1741 tatgtaaacg gacatccgca cggacctgca accggcgcaa ctacttgcca gctttatatg
     1801 cgtcgcttca atgatggcga aactattaca atcgaaccgt ggcgttctgc cggtttcccg
     1861 gtaatccgcg acttgatggt agaccgttat gcttacgata aaattatcca ggcaggtggt
     1921 ttcgtatcag tgaacacagg tggtgtacct gatgccaatt caatcgctat tcctcgtgca
     1981 gatgctgaaa tggctatgga tgctgctgca tgtatcggtt gcggtgcttg tgctgctgct
     2041 tgtaagaacg gttcggctat gttgttcgtt tctgcaaagg ttagccagtt ggctctgttg
     2101 cctcagggta aggtagaagc tgctcgtcgt gcgaaagcaa tggttgccaa gatggacgaa
     2161 ctgggcttcg gtaactgtac caacacgcgt gcttgcgaaa tggaatgtcc gaagaacatc
     2221 tctgtcagca acatcgctcg tttgaaccgc gagttcattt gtgctaaatt gcaagactaa
     2281 tatacattat atatgtatgt ccggagaggc gttgcttatg gcagcgcctc ttcttttttg
     2341 cccctatttt aacatttctg aagtcataga taaatatctt gaatgttgtt agtgtttctt
     2401 atatgctata caacactaat tagcatttta actattgaca agttggagaa tacctgtatc
     2461 tttgtactgt ggttttttca taatagtatt agatttaagg ttaacaaagt tggttagggc
     2521 ttgtcgtgag acaggcttta attgtttata ggggtttgcg tccggcatat cccttttttt
     2581 agctctccct gtattcctgc ggggtcattc ctacatgttg ccggaaatat ttgttgaaga
     2641 acgaaaggtt gtcgaaaccc agggcgaatg caattttctt gaccggcata tcggtcgatt
     2701 taagctgcgc tttggcatcc ataatgatga tattgctcag gatatccaat gcagtccgtc
     2761 cgctgacctt ttttatcaca taacagaaat gctgcaaggt gatgttgagc cttttggcgt
     2821 aataagacac gctatgctct ttcgtgtagt tttccatcgc cagttgtacg aactcccggc
     2881 atatttccat gttacgcgtc atgggagcat tgctatatgg cgtatgattc ctgtataatt
     2941 caataacccc ttgcatgaag atagtaaaga ttgccttgat aatctccttg ttctcgatgg
     3001 ttttaggcat ggaataagca ttgatcagca agtcgaaagc ctgttggtag agtaaggata
     3061 tatgttccgg cagaggcatg atcggactgt cgaatatgac aggcagatag ttcgtaatcg
     3121 tctttatata attgatatgg ctgacgaata cggaagaaaa gcctgcaaaa cacagtttta
     3181 catcatcgga aacctcatgt atctgaatga agcaacccgg gggtaaggtg ataaagtcgt
     3241 tcttccggat ggtaaactca gttaagttta cagtcgcgtg gactgtccct tgtacgcaaa
     3301 gcacgaatat gccagccttg atcttgcacg ggaaacgtcc gtactggttc agtatttcac
     3361 ctgtaatact gtttcctaca ataaaatcta cggggaggtc gaatttagga atattgtctt
     3421 ccatactttt atatacactt aattgaatgt acaaagatag tttttttgag acaagttagt
     3481 cgataatctt aaatatagaa catcgaatcc cacaaatgga gattgttttg tgctgtataa
     3541 tagttgaaat ttgcgaatgt tttcaagtct tgctgataga tttgttggga tggtatatat
     3601 ttgtctatct gctaaataag atatgggagc taatactaat agagaaatct aatcgataat
     3661 aacaatgagt acgaaaagaa caaagagctc tttcaggaca atgagcacaa acagaaaatt
     3721 agaatctgtt ttcctgtttg tcacaggacg gtgtaatgct aaatgtaaaa tgtgtttcta
     3781 tgcagaagac atggataaaa aggagaaaga cctgactttt gaagaaatca agacaatctc
     3841 cgaaacagcc gggcagttca accgtttgtg ggtatccggc ggtgaaccga cactgcgtga
     3901 ggagttacct gaaattatag agatgttcta caagaataac gagataaagg acgtgaatat
     3961 ccctaccaac ggattgaagc ctgaccggat cgtcgcctgg gtaaaacaga tccgccagaa
     4021 ttgtccggaa ctgaatatca acctgagcct ttctttggac ggtttcggtg atacgcatga
     4081 tatacagcgc ggcgttcccg gcaatttcta caaagcgatg gggacactga agctgattga
     4141 aaaaaacttt gctgacgacg gcagggtgtt gaaaaacctg gccaccgtaa tcaccaaata
     4201 taacgagaat gaggtcgagg atctgatgat atggatgctg ggacgtttcc atctttccaa
     4261 tcatattatt gaagctgcac gcggtatgac ccgcgacgac ggagtgaagg ttcttaccga
     4321 gcctactcta cgcgccttgc aggataaggt tgttcctatt tataatgtat atggggagcg
     4381 tatggcggag gaaaccggtg ggttcagaaa acctatcgcc cgtttcttct acctgggttt
     4441 catacgtaca ttatataatg tacgtgcgac caatatcgat catccgacac cctggggtat
     4501 ggattgtacg gccggcgaaa caacactggt aatagactat gacggtcgtt tccgtgcctg
     4561 tgaacttcgc gaaccgctcg gtaatgtcaa ggattatgac tgcaatatcg caaagattat
     4621 ggagagcgat gccatgaaac aagagattgc cgctatcggt catggtgaca aggctaactg
     4681 ctggtgtacg catgggtgtt ggatcacttc atcgcttgtt ttcaatcccc gcaagatgat
     4741 cacgcaggtc tataaaggat accgggagat gaagaagctg aaccgtcctc tgaatatcag
     4801 tgaagagctt ttgcagagta tcgaacgcaa atatgccttg gacgaacaga aactggtgga
     4861 gctgggagtt cgtaattaaa atagttccga taacggatca tttataaagc cggttgacgg
     4921 gaaatatacc tctgttaacc ggctttattg tgtttaaggg aataattgtc aaattatccg
     4981 gtagaattgc catttcccat aggggaaaaa tgtcggatct ttgcatcata agttaaactg
     5041 ataaacaaag aaagacatga ctactaaatt aaaagattta ttcgacacat ttctgaacat
     5101 tgcagcttct tcacagaaac tgggtattaa cctgatccgc gtagctatcc tgattatatt
     5161 cgtatggatc ggcgggctga aattctataa ttatgaagcg gaagggatcg ttccttttgt
     5221 ggcaaacagt ccgtttatga gctttttcta tgcaaagagt gcaccggaat acaaagaata
     5281 taagttgaaa gaaggtgaat tcaatgaagc caagcatcag tggcatgtag aaaacaatac
     5341 ctatattttt tcacatggac taggcattat gatcatggcg atcggtatcc tgactttcct
     5401 gggtatcttt tctccgaaaa ttggcttgat aggttccgga ctggcgatca taatgacatt
     5461 gggtacgctt tcattcctgg tgacaacacc tgaagtgtgg gtgcccgatt tgggaagcgg
     5521 agaacatggt ttccccttac tgaccggagc aggtcggctg gtaataaaag atacggcaat
     5581 catagccgga gcgatcgtgg tattgtccga ctgtgcacaa cgtatattaa agaagaaata
     5641 ggaataaaaa gtgtttattt taacactttg gaagcaaaaa acaaacatat tgaaccttgt
     5701 tagcttttct tatagtgtat gaaacaccat ttagcataaa acctcttgac aggtttggat
     5761 taagcagtat atttgcatcg tggttttttc ataatagtat tagatttaag gttaacaaag
     5821 ttggttaggg cttgtcgtga gacaggcttt aattgtttat aggggtttgc attcggaaat
     5881 gcaagccttt tttcttttaa atatggcatt ctctgaaaaa taactccctt ttttatcggt
     5941 aatattcggc aattcaccga tatttgactg taataggacg tatttctatt gccggaaggc
     6001 tgacaggagc atacttttgc tctcaaacaa ttaaactgta tatcgtatga atcttaggaa
     6061 aaacttattt tgggccatcc cgtttattgt agtgggggtc gtatggatca tgaggaacac
     6121 aggcatgatc acggatgatc tttttcatat cattgtatcc tggcagatgc ttgtaatgta
     6181 tataggtata gggagtattt cccggagaca ttatataggc ggtttgatta cctttttggt
     6241 tggtgcggca tttttactgc cacgactggg gtggatggat agcgattggt tgcaggtcta
     6301 ttggccggct gcttttgtca ttgtcggttt aatgctgatc ttcgaaccgc gtaaaaagaa
     6361 ctcctatcat tacaatagcc ggagagagga taccggtgga gaagatatcc ggggaaatgc
     6421 cgttgccggt aaagtaaaaa gtgattttat taatacggac ggatatgtgg aatcggataa
     6481 tacatttggc tatgtggaac aaattatttt agatccggta tttaaaggag ccaggattag
     6541 gactgtgttt gggggaacgg tcctggattt gcggaaaacg aagctggata gtgctaaaac
     6601 ctatattgat atcgattgta agtttgccgg tgtggaaatc tatcttcctg gggattgggc
     6661 ggtcaatttt catggcagtc cgatcatggg ggcatgcgag gataaacgtt ttaatgcctc
     6721 tatggaaatg gataaagaac atatactggt tgtacgggga attgttatgt tcggtggcat
     6781 tgaatttaag agttgattat gcagacacat ccgtttataa attctgtcct gtgtagaatg
     6841 gctggtgtgg ctttggctgt ggtcagttgc agcataagcg ccttgctcct ctattattac
     6901 ggacatacgg gatggcttgt cgcatggttg gatagtctgg tttcggtcgg tatattctgt
     6961 gtctccggtt tcctgttctg gtatgtaaca ggcatattgc ggccattaca ggcccagatt
     7021 gcattggctg ttggcgtcct tatcatatcc gttaccggag gatatatggc cggggcgctg
     7081 gtttatccgg ataggatgga ttggtttgca tctaccattc cgttccgtat tttgttgggt
     7141 ttgctgggat ggattatttt ggcccagtgg tattatatcc gttggaagga gttgcagatg
     7201 gagatacagg aggaacagag aaaagaagaa aatgctccgg cggaaacagg cgtatcgtca
     7261 ccggaagagg aagcaatact ggatcgcatc tctgtgaagg atggcagccg tatccatctg
     7321 atccacctgg aggagttact ttatatccag gccagcggtg actatgtggc actcttcacg
     7381 accgacggac agtatataaa agatcagaca atgaaatatt ttgaatcgca tctgccggca
     7441 aacctgttta tccgtattca ccgttcctgt atcgttaata gcgaacagat catgcgtgtg
     7501 gaactgttcg gcaaggaaag ttaccaggtt cgtcttaaaa caggtgtctg tctgcgtgcc
     7561 agcctgaccg gatacaagtt gcttaaagaa cgtctttctc tatagatttg gctgttttaa
     7621 ctgttaaaat tagcagtttt tgtctgtatt gtataaagtt ttgtgttcgg aaacaatttt
     7681 tagctacaat gcccgaaagg cttaacatat attgtctgta aaagacttga caaacgcttg
     7741 tttcaggctt atctttgtac tgtggttttt tcataatagt attagattta aggttaacaa
     7801 agttggttag ggcttgtcgt gagacaggct ttaattgttt atagggggtt cttttctcat
     7861 cattttgtat gaatctttga ttttgaggtg ttatctttgc aagctatgga atatatagga
     7921 ctgcatgaag ataaaatatc acttgctgat attataaaat atctttctct tttgaaaggt
     7981 aatatggatg aattgaattt gcttgaattc aaaaccatta aaggttggtt ggtttattct
     8041 ttgtcattag ttcttttgtt gtgtatacct tgtgtaatca ttttattaat aacaggtctt
     8101 ttatccggaa atatagatag cggattatta ttggctgttt cttttatccc tttcctcttt
     8161 attttgcctt tgacattgtt attgactttc atcaacaatt acagaaaacc caaaaagttg
     8221 agggaactaa tgcagacggt tttgatgcgt tacgaatggg atggtcctat caatcaaacc
     8281 ggacggttgc agttggaatg caggaaggac cattttctgt ttagaacgga agttttgcgg
     8341 caaatgaatc ccaaagggcg taatgtgtct ttgattttca tatccgttcc tttctatgta
     8401 ccgatagaaa aggagctgat acatgccgaa gatataattg cttatctgaa aggcaagtct
     8461 cttttcgtga ttgagccaga tatggcatgt ttgggaatgt cgtttaaaat gtttcagaaa
     8521 ctggatttgc gtgaagatat tgatcagttg atttatgtga tgaaacgttt ttcccttcgc
     8581 cccggaacac tcttcaaggc gcaggatata actttgaaag ttcctgaaac actggaaata
     8641 caggcactgt ttattttcgg tcaaaaaata gaccaaaggt ttctgaattg ggctaacctg
     8701 atgcttgatg ccggatttgt gagtgataat atgaaaatta tggctgaaca agcatctctg
     8761 actctccctc aaaaagaatt gaagaaaaga gtggaggtga ttttcctgga gtttaatttg
     8821 tatttctcta aagagactgt attaaataat tatttgatat tccttatact ggaagaacag
     8881 gaagaacgaa ggtctgtttt ggagattata caatgtctgg ccagtctcta tcaatcttcc
     8941 aggctgcctc tgttgcaaga atatgatctg ttatataaag ctaaaagggc attggatgaa
     9001 acaggagaac aaaatttctg gacggcagac ccgcctttga cggtcgataa tgtggatact
     9061 tatatattaa cctatttgac cagaaggcta gctgacctga tagcctctcg agaaaaggat
     9121 cagtgatcga tcatcccttt gtaacagatg cgtcaaaaaa tgacgtaaat gttgcatttt
     9181 tattaaacct ctatgaatta agcgcataat tacaaataat tggcgagttc gtgctttttg
     9241 tgctattgtt tattgattta gtttgcacca tcaaccttga ataagtaaaa taaatttgat
     9301 agacatgaaa gcactattgt taactgttgc cctgctgctg gggtgcgtaa ccgtttcctc
     9361 acaggataaa gatacgggga taattaccgt ctctacaaac gatctgagta tggtcttttc
     9421 gatctctccg gataagaaag tagtgtataa ctattttggc gataaattcc aggacgtttc
     9481 ccctttcctt cataagaagt ataaagaaca accggataac ggaatcggtt atgctccggt
     9541 aatctatccg gcttacggag gacgtttctt cctgaatccg gcattgaaac tgacccatga
     9601 cgacggcgtt cagacaaccg aattaatata tgcagctcat caggtaaaga atatagataa
     9661 taatagaata gaaacagtga tacaattgaa agatcctttg tatccggttt tcgttaacct
     9721 gaacttcacg gcttatcaga aagaaaatgt aatctgccag tcagtctcca tatcccatca
     9781 ggagaaaaac aagctggctg tcgagaatat tgcctccgct tatcttcccc ttcatgcaga
     9841 ttcttattat ctgacccatt tccacggggc ctgggcttcc gaaatgcaac tggtagaaga
     9901 acaactgaca ccgggtgtga aacgggtgga atccaagaag gggatacgta ctacccagtc
     9961 tgaaaactct tctttcctgc tttccctgaa tggccctgcc aatgaagaca tgggcgaagt
    10021 gtatgccggc tccctggcct ggttaggtaa ctatctgtct tcctttgaga tagacgaatg
    10081 cggtttgctg catgtcatga gcgggatgaa tgattttgcc tctacttata atctggaacc
    10141 gggtaaaacg ttgcagactc cggaaatggt ctggacatac agttctaccg gtaagggaca
    10201 ggtatcgaga aacctccatg actggtcgcg taactatgca ttggcccatg gagatcagga
    10261 attgcctatc gtcctgaata gctgggaagg cgcttatttc gattttaatg aaaaaacgat
    10321 tacggatatg atcgatgacg ctgctgcttt tggcgttgaa atgttcgtac tcgatgacgg
    10381 atggttcgga aataaatatc cccgcaattc ggataaggtt ggtttgggcg attggcaggt
    10441 gaacaggaaa aaactgccac gcggaatcga ttatctggcg aagcatgcgg taagtaaagg
    10501 attgaagttc ggtatctgga ttgagcctga aatggtaagt cccaagagtg aactggcaga
    10561 gaagcatccg gaatggatcg tcaagagcgg taaacgtgat ataatcccga tgcgtaacca
    10621 gtggttactc gatttgagta atccggaggt acaggacttt gttgtaaaga cgtttgatga
    10681 agtgatcgct ttgtctcctg atatctctta tataaaatgg gatgcaaacc gtcacgtgga
    10741 taatttcggt tccgaatatc tgtccaaaga aaatcagact catttctgga ttgactatac
    10801 aaagggcttg tacagtgttt acgaacggat tcgtgcaaaa cacccggatg ttcttattca
    10861 gttgtgttct tcgggtggcg gccgtctcga cttcggtgca ttgaaatatc atgacgagtt
    10921 ctgggctagc gataacacca attcgcttga ccgtatattc atccaataca gcacaaatct
    10981 tttcttcccg gcaaaggcta cggccgccca tgtttcgact actccgaatc atcagacggg
    11041 tatgatggcg ccgctgaagt tccgttttga tgtggctatg acaggccgcc tgggcatgga
    11101 gctgcaaccc gaagacttga ccggcgacga actacctttc gctgagcaag ctataaagaa
    11161 ttataaacgt atccgcccga tcgtacagtt tggagacctc tatcgcctga aatctcctta
    11221 cgacggaacc ggctgggctt cacatatgta tatatctaag gataaaaagg aatcggtgtt
    11281 ttttgcttat agcctgaaat accacggacg tacaacattc tttgagacca gattgaaagg
    11341 actggaccca gctaaaatgt ataagatcac agagttgaac aaagccggga acagcacctt
    11401 ctatggcgac ggtcaggttt tccccggtga ttatctgatg aaagccggaa tcagcctgac
    11461 gatagggaat acttatgaaa gtaccgttct gttgataacg gaacaatgaa actatctata
    11521 aattatcaat acatgaaact catcaattta aatctgctgc tattgctcgc cctgcttgta
    11581 tcctgcggcg aatcatccgt ttcttcggga aagtggacgg ttagctatga ccaggtgcag
    11641 aaaggccacc gtatcgagaa ggagaaccag cttctttccg atggggttta tgcctcctac
    11701 aagttgggta ataagttggt cacgacccgt gactacaaaa agagcagttc gaaagtcacc
    11761 gctatcagcg atgctttcgg tcagggttca ttgttgcagg tgacctacac ggatagcaac
    11821 ctgcctacgc ttgtacaatc tttctacatc tatccggaga aagattatct gctgacggaa
    11881 tttactcttc agggaggagc cgctgacgtt gaatcgaatt atatggcccc ggttactatc
    11941 gaccgcatgc cggccgtgtt ggctgaaggt gataaccgcg cgttattcca gcctttcgat
    12001 aacgattgct ggatacgtta tcagtctcat ccgctcactt tcgatcaatt acgtagctat
    12061 gaagtagcga ctgtcttcaa caacgacgac cgtaaaggtt ttgtcatcgg ttcagtggaa
    12121 cactccgact ggaagaccgg tatcgatatg gggaaaggcg accgtaataa tatcggttca
    12181 ttggtttgct tcggcggcgt tgccgattcg ttgacacgcg actctaaggc acacggtgct
    12241 ttaaaaggaa aaatggtaaa gtctcctaag gtatttttcg
//
