LOCUS       c00104_gnlPro..        11596 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|PFAECEBB_104.
ACCESSION   c00104_gnlPro..
VERSION     c00104_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-07 20:30:29
            Original ID  :: gnl|Prokka|PFAECEBB_104
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 11596
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..11596
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[2199:8281]"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      2200..8281
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
     cand_cluster    1..11596
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /kind="single"
                     /product="TPP_AA_metabolism"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..11596
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="TPP_AA_metabolism"
                     /region_number="1"
                     /rules="(TPP_enzyme_C and not (PFL-like or PFL_6_pcresol or
                     PFL_9_tma or Gly_radical or Gly_430_pcre or Gly_8-9_TMA or
                     PFL_acetate1 or PFL_acetate2 or Gly_radical_scatole or
                     PFL_proline or PFL_toluene) and minimum(2, [ALS_ss_C,
                     AlaDh_PNT_C, Arginase, BKACE, BcrAD_BadFG, Beta_elim_lyase,
                     CPSase_L_D2, Cys_Met_Meta_PP, ELFV_dehydrog, GRDB,
                     Glu_syn_central, Glu_synthase, Gly_reductase, HAAA1, HG2B1,
                     HG2B2, HGD-D, HleuD1, HleuD2, HleuS1, HleuS2,
                     Homoserine_dh, ILVD_EDD, IlvC, Lactoyl-CoA1, Lactoyl-CoA2,
                     Lyase_aromatic, MAAL_C, OKR_DC_1_5_lysine,
                     OKR_DC_1_5_ornithine, OKR_DC_1_7_arginine, OKR_DC_1_C,
                     OTCace, PALP, Proline_reductase, Sacchrp_dh_C, TPL,
                     Thr_dehydrat_C, TnaA, Urocanase]) and not (POR or POR_N or
                     PFOR_II))"
                     /tool="gutsmash"
     CDS             complement(3..110)
                     /locus_tag="ctg104_1"
                     /transl_table=11
                     /translation="MVYDLTMLKTFYAAYSEKIERVRNVLRRPMTLAEKI"
     CDS             225..2138
                     /locus_tag="ctg104_2"
                     /transl_table=11
                     /translation="MITFATMKEQDSNSPIIHLQQQQLLLRMEYEYEKEEFKRQTENMG
                     VARKVKRGLCWYPATPGRSYYNSLNQLVIEITHTENTDIEHNFEFGRPVCFFRQSADGK
                     ITYMNFTATVSYADETRMVAIMPGAGAVMEVQETDNLGVQLYFDETSYRTMFEALEDTL
                     RSKGNRLAELRDILLGTSKAGFRELYPVRFPWLNSTQETAVNKVLCARDVAIVHGPPGT
                     GKTTTLVEAIYETLHREPQVLVCAQSNTAVDWISEKLVDRGVNVLRIGNPTRVNDKMLS
                     FTYERRFENHPLYPELWSIRKNLRELGSRARRGSYDEREGVRSRMSRLRDRATALEIQI
                     NSELFDGAHVIASTLVSSNHRLLNGRRFGTLFIDEAAQALEAACWIAIRKADRVVLAGD
                     HCQLPPTIKCHEAARGGLERTLMEKVVSNKPAVVSLLKVQYRMHEEIMKFPSQWFYNGE
                     LEAAPEVRYRGILDWDTPIHWIDTSEMDFKEEFVGETFGRINKAEADLLLSELKIYINR
                     IGGSRILEEKIDFGIISPYKAQVQYLRNKIKADASLKPYRSLFTVNTVDGFQGQERDVI
                     FISLVRANEEGQIGFLNDLRRMNVAITRARMKLVILGEAETLKHHGFYRKLLEFIQNIG
                     NQ"
     CDS             complement(2200..3243)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: IlvC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) IlvN"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg104_3"
                     /sec_met_domain="IlvN (E-value: 3.9e-47, bitscore: 149.3,
                     seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="IlvC (E-value: 3.5e-41, bitscore: 130.3,
                     seeds: 295, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAQLNFGGVIENVMTREEFPLEKAREILKDETIAVIGYGVQGPGQ
                     ACNLRDNGFNVIVGQRPGKTYEKAVADGWVPGETLFGIEEACQKGTIVMCLLSDAAVMS
                     VWPTIKPYLTPGKALYFSHGFAITWNDRTGVVPPKDIDVIMVAPKGSGTSLRTMFLEGR
                     GLNSSYAVYQDATGKAFDKTIALGIGIGSGYLFETTFIREATSDLTGERGSLMGAIQGL
                     LLAQYEVLRENGHTPSEAFNETVEELTQSLMPLFAKNGMDWMYANCSTTAQRGALDWMT
                     PFHDAIKPVVQKLYASVKSGNEAQISIDSNSKPDYREKLNAELKALRESEMWQTAVTVR
                     KLRPENN"
     CDS             complement(3294..4046)
                     /locus_tag="ctg104_4"
                     /transl_table=11
                     /translation="MMSENNKIGTYKFVAEPFHVDFTGRLTMGVLGNHLLNCAGFHASD
                     RGFGIATLNEDNYTWVLSRLAVELDEMPYQYEDFSIQTWVENVYRLFTDRNFAIIDKEG
                     KKIGYARSVWAMISMNTRKPADLLALHSGSIVDYVCDEPCPIEKPSRIKVASKEPVAAL
                     VAKYSDIDINGHVNSIRYIEHILDLFPIEMYKEKRIRRFEMAYIAESYYGDELTLFMDD
                     AGEGVYDVEVKKNGSEVVCRSKVIFTEK"
     CDS             complement(4043..4603)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ALS_ss_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg104_5"
                     /sec_met_domain="ALS_ss_C (E-value: 6.1e-20, bitscore:
                     60.8, seeds: 685, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDKKLYTIIVHSENFAGLLNQVTAVFTRRQINIESLNVSASSIKG
                     VHKYTITAWTDKDTIEKVTKQITKKIDVLQAHYFTDDEIYQHEIALYKITTPTLEEKPE
                     VSKVIRKYNARIVEVNAVFAIVEKNGMSEEITNLYEELRQLDCVLQFVRSGRVAITTSC
                     FERVNEYLADREAKYRQSKHQES"
     CDS             complement(4636..6387)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg104_6"
                     /sec_met_domain="TPP_enzyme_C (E-value: 8.5e-48, bitscore:
                     151.4, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MADNNKKSNFSSLSQGEGRGEALITGAEALMRSLEHQGVKTIFGY
                     PGGSIMPVFDALYDHRKELNHILVRHEQGATHAVQGFARVSGEVGVCLVTSGPGATNTI
                     TGIADAMIDSTPIVVIAGQVGTNFLGTDAFQEVDLVGITQPITKWSYQIRRAEDVAWAV
                     ARAFYVAKSGRPGPVVLDFAKNAQVEKTEYAPTKVDYVRSYLPVPEMEPEAIRKAAELI
                     NGAERPLVLVGQGVELGEAQQELRAFIEKAGMPAGCTLLGLSALPTNHPLNKGMLGMHG
                     NLGPNINTNKCDVLIAVGMRFDDRVTGKLETYAKQAKIIHFDIDPAEIDKNVKTDVAVL
                     GDCKETLAAVTQLLEPANHQEWIDSFRQYEEVEEEKVIRPELHPAGKALSMGEVVRAVS
                     EATHNEAILVTDVGQNQMMSARYFKYSKERSIVTSGGLGTMGFGLPAAIGATFGRPDRT
                     VCVFMGDGGLQMNLQELGTIMEQKAPVKMILLNNNFLGNVRQWQAMFFNRRYSFTPMMN
                     PDYMKIASAYDIPARRVMTREELAKAIDEMIATDGPFLLEACVEEEGNVMPMTPPGGSV
                     NQMLLEC"
     CDS             complement(6479..8281)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ILVD_EDD"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg104_7"
                     /sec_met_domain="ILVD_EDD (E-value: 2.6e-219, bitscore:
                     718.4, seeds: 918, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKHQLRSSFSTQGRRMAGARALWTANGMKKEQMGKPIIAIVNSFT
                     QFVPGHVHLHEIGQFVKEEIEKLGCFAAEFNTIAIDDGIAMGHDGMLYSLPSRDIIADS
                     VEYMVNAHKADAMVCISNCDKITPGMLMAAMRLNIPTVFVSGGPMEAGEWNGQHLDLID
                     AMIKSADESVGDKEVAQIEQHACPTCGCCSGMFTANSMNCLNEAIGLALPGNGTIVATH
                     ENRKKLFEDAARLIVENAFRYYEEGDESVLPRSIATREAFLNAMTLDIAMGGSTNTVLH
                     LLAVAHEAGADFKMDDIDMLSRKTPCLCKVAPNTQKYHVQDVNRAGGIIAIMDELAKGG
                     LVDTNVRRVDGMTLAEAIDRYSITSSNVCKEAIKKYSSAAAGKFNLVLGSQNASYKELD
                     TDRATGCIRDLEHAYSKDGGLAVLKGNIAQDGCVVKTAGVDESIWKFTGPAKVFDSQDA
                     ACDGILGGKVVSGDVVVITHEGPKGGPGMQEMLYPTSYIKSRHLGKECALITDGRFSGG
                     TSGLSIGHVSPEAAAGGNIGKIKDGDIIEIDIPNRSINVKLTDEELAARLMTPVTRNRE
                     VSKALKAYASMVSSADKGAVRLID"
     CDS             8771..9343
                     /locus_tag="ctg104_8"
                     /transl_table=11
                     /translation="METVENKYITVAYKLYSIENGEKDFEEEAPVEHPFQFISGLGMTL
                     EPFEAQIKDLQIGDKFDFTIPASEAYGEYDDDHVIDLPKEIFMIEGEFDSDRVVEGAVI
                     PLMTSEGQRINGSVVEVKEDIVVMDMNHPLAGCDLNFTGEVVESRLATNEELAEVARMM
                     GGGCGSCGCGDCGDGCGDHECGGGCCH"
     CDS             complement(9443..10723)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) SDH_alpha"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg104_9"
                     /sec_met_domain="SDH_alpha (E-value: 1.8e-62, bitscore:
                     200.7, seeds: 645, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTKTERQQIIDLVKSEVVPAIGCTEPIAVALCVAKAAEVLGRHPE
                     KITVLLSANILKNAMGVGIPGTGMIGLPIAVALGALIGKSEYQLEVLKDCNPDAVEEGR
                     RFIDEKRIHIALKDGIKEKLYVEVCCEVGDEKSTAIIAGGHTSFVYMARNGEVLLNKQA
                     VASTEKEEGALDLSLRKVYDFALTAPLDEIRFILETARLNKAAAESSFEGDYGHGLGKI
                     LRGTYEHKVMGDSVFSHILSYTSGACDARMAGAMIPVMSNSGSGNQGISATLPVLIYAE
                     ENGKSEEELIRALMLSHLTVIYIKQSLGRLSALCGCVVAATGSSCGITWLMGGTYEQVA
                     YAVQNMIANLTGMICDGAKPSCALKVTTGVSTAVLSAIMAMENRCVTSVEGIIDEDVDQ
                     SIRNLTKIGSKGMNETDKLVLEIMTSK"
     CDS             complement(10870..11595)
                     /locus_tag="ctg104_10"
                     /transl_table=11
                     /translation="KNLFFLFALICSMSLFTACSDDDDDKIKDPVIGTWKVPAVELDEN
                     NSVIGGSVFMTWEAPEDTYLSFLPVSAIPSLAIQMGSVILPQVLQDVTLSADGNIVATY
                     SSAGIDLSPVWETSPADYATFKLQGNGKMLLFLNLEKIIADANTKADITTVISQLLELV
                     KNGIPVNYALSNNNEEVKIFIDKELMTTIAAMGPAIAELIPDPDALGSFGPMIKAILGD
                     LPTAMSKTTKFELGLNLKK"
ORIGIN
        1 aaaattttct ctgctaaagt catcggacgc cgcagtacgt tccgtacgcg ttctatcttc
       61 tccgaataag cggcataaaa cgttttgagc atcgttaaat catataccat aaccactatt
      121 ttttagtttt tcattattgt aaagattaca aattaatatc ataaacaaat aaaaaggctg
      181 aatagtttaa caaaataaag cattttttct gtcggaagcg aagaatgatt acctttgcaa
      241 ccatgaagga acaagattca aatagtccta ttattcacct ccagcagcaa caacttttgc
      301 tgcgcatgga atacgaatac gaaaaagagg aattcaaacg ccaaaccgaa aacatgggag
      361 ttgcccggaa agtgaaacgg ggactttgct ggtatcctgc cactccggga cgaagttact
      421 ataattcact gaatcaatta gtaatagaaa ttacacacac agaaaatacc gatatagaac
      481 ataattttga gttcggccgt cccgtatgtt ttttccgcca gtctgccgat ggaaaaataa
      541 cctatatgaa cttcaccgct accgtaagct atgccgacga gacacggatg gtagcgataa
      601 tgcccggagc cggtgccgtt atggaagtgc aggaaacgga caacctcggc gtgcaacttt
      661 atttcgacga aacatcctat cggaccatgt tcgaagcctt ggaagatacg ttacgctcca
      721 aaggcaaccg cctggccgaa ttgcgggaca tattgctggg aacctcgaaa gccggtttcc
      781 gagagctcta ccccgtacgg tttccctggc tgaactccac gcaggagaca gctgtaaaca
      841 aagtgctgtg tgcccgcgac gtggccattg tacatggtcc tccgggaacc ggaaaaacga
      901 ccaccttagt ggaagccatc tacgaaaccc tgcatcggga accgcaggta ctagtatgtg
      961 cccaaagcaa tactgccgtc gactggattt cggaaaaact tgtggaccgt ggcgtcaatg
     1021 tcctgcgtat cggcaatccg acccgtgtca acgacaagat gctttccttt acctacgagc
     1081 gtcgtttcga gaaccatccg ctttatccgg aactgtggag catccggaaa aatctccgtg
     1141 aactgggcag ccgtgcccgc cgtggcagct atgacgaacg cgaaggagta cgcagccgta
     1201 tgagccgcct gcgcgaccgc gccaccgcat tggaaataca aatcaattca gagctttttg
     1261 atggggcaca cgtcatagcc tccacgctgg taagcagcaa tcaccggctg ctgaacggac
     1321 gccgtttcgg cacccttttc attgatgaag cagcccaggc cttagaggct gcctgctgga
     1381 tagctatccg aaaagcagac cgcgtggtat tggcgggtga ccactgccaa cttcccccca
     1441 ccataaaatg ccacgaagcc gcccgtggag gtctggaacg aacattgatg gagaaagtgg
     1501 tgtccaacaa acctgccgtt gtctctttgc tgaaagtgca ataccgcatg cacgaggaaa
     1561 tcatgaaatt tccttcccaa tggttttata atggcgagtt ggaagccgct cccgaagtgc
     1621 gttaccgggg catcctggac tgggataccc ctatccactg gattgacacc tccgaaatgg
     1681 atttcaaaga agaatttgtg ggagagactt tcggacgcat caataaagcg gaagcggacc
     1741 tgctcctatc agaactgaaa atctacatca accgtatcgg tggcagccgc attctggaag
     1801 aaaaaataga cttcggcatc atctcccctt acaaggcaca agtgcaatat ctccgcaaca
     1861 agataaaggc agacgcttca ctcaagcctt atcgcagctt gttcactgta aatacggtgg
     1921 atggcttcca agggcaagag cgcgatgtta tcttcatcag ccttgtccgc gccaacgaag
     1981 aagggcagat aggattcctg aatgatttaa ggagaatgaa tgtagccatc acccgggcac
     2041 gtatgaagct ggtgatattg ggagaggcag agacgctgaa acatcacggt ttttaccgga
     2101 agctattgga gtttattcaa aatataggga atcaataata aagaaatacc ccctccggta
     2161 acaccgaaga gggtatttca cctatttata taaagctgat taattgtttt ccggacgaag
     2221 tttacgaact gtaacagctg tctgccacat ttcgctttca cgcaaggctt tcaattctgc
     2281 attcagcttc tcacgataat cgggtttgga gttgctgtcg atagaaatct gagcttcgtt
     2341 acccgacttc acgcttgcat acaatttctg tacaaccggc ttgatggcat catggaacgg
     2401 ggtcatccaa tccagcgcac cacgctgtgc cgtagtagaa cagttggcat acatccagtc
     2461 cataccattc ttggcaaaca atggcatcaa agattgagtc aactcttcca cagtttcatt
     2521 gaatgcttca gaaggagtgt gaccgttttc gcgcaatact tcatactgag ccaacagcaa
     2581 tccctggata gcacccatca atgaaccgcg ttcaccggtc aagtcggaag tggcttcgcg
     2641 gatgaaagtt gtctcgaaca aatatcccga accgataccg atacccagtg caatcgtctt
     2701 gtcaaaagcc ttacccgtag catcctgata gacggcatat gatgagttca agccacgccc
     2761 ttcgaggaac atggtacgaa gtgaagtacc ggaacctttg ggagcaacca taataacatc
     2821 aatatcttta ggaggaacca cgccggtacg gtcgttccag gtaatagcaa aaccatgaga
     2881 gaagtaaaga gcctttccgg gagtcaaata aggtttgata gtcggccata cagacattac
     2941 agctgcgtca gacaacagac acatgacgat agtacctttc tgacaagcct cttcgatgcc
     3001 gaacaaagtc tcacccggta cccatccgtc agccacagcc ttttcgtatg tcttacccgg
     3061 acgttgtcct acaatcacat tgaaaccgtt atcacgcaag ttgcaagcct ggcccgggcc
     3121 ttgtacgcca taaccgatta ctgcaattgt ttcatctttc aaaatctcac gtgctttttc
     3181 caaaggaaat tcttcgcggg tcattacatt ctcaataaca ccgccaaaat tcaattgtgc
     3241 cattttttgt tttaattttt atttgtggct tacgccaacg ttgataaatt tatttatttc
     3301 tctgtaaata tcactttaga gcgacagacc acttcgctgc cattcttttt cacctccaca
     3361 tcgtaaacgc cctcaccggc atcatccatg aacaaagtca actcatcccc ataatagctt
     3421 tcggctatat atgccatttc aaaacgacgg atgcgcttct ccttatacat ctctatcggg
     3481 aacaaatcaa ggatatgctc gatgtaacgg atgctgttca catgcccgtt aatgtcaata
     3541 tcactgtatt tggctaccaa agcagcaacc ggttcctttg aggccacctt tatccgcgaa
     3601 ggtttttcta tcgggcaagg ctcatcgcaa acataatcta caatgctgcc actatgaaga
     3661 gccagcaaat ctgccggctt acgggtattc atgctaatca tcgcccaaac ggaacgtgca
     3721 tacccaatct tcttaccctc cttatcgatg atagcgaaat tacggtctgt aaaaaggcga
     3781 tagacattct ccacccaagt ctgaatggag aaatcttcgt actgataagg catttcatcc
     3841 agttcgacag ccagacggga caatacccaa gtataattgt cctcgtttag agtcgcgatg
     3901 ccaaaaccgc ggtcgctggc atggaaaccc gcacaattca acaaatggtt gcccaatact
     3961 cccattgtca gccgtccggt aaagtcgaca tgaaacggtt cggcaacaaa cttgtaggta
     4021 cctatcttat tgttctcgct catcatgatt cctggtgttt actttgacga tattttgctt
     4081 cacggtccgc cagatattca ttgacacgct caaagcagct ggtcgtaatg gctacgcgac
     4141 ccgaacggac gaactgaagt acgcaatcca actggcgcaa ctcctcataa agattggtta
     4201 tttcctcact catgccattc ttctcaacaa tggcaaatac agcattcacc tccacaatac
     4261 gggcattgta cttacggatt actttggaca cctccggttt ttcttccagc gtaggggtcg
     4321 ttattttata aagggcaatc tcgtgctgat agatttcatc atccgtgaaa taatgggctt
     4381 gcagcacatc tattttcttg gtaatctgct tggtcacctt ttcaatggta tccttgtccg
     4441 tccaagcggt aatggtatat ttatgtaccc ccttgatgga ggaggccgat acattcaaac
     4501 tctcgatgtt tatctgccgg cgggtaaaca cagccgtcac ctgattcagc aaaccggcaa
     4561 agttttccga atgaacaatg attgtatata gttttttatc catagataga gtaagttctt
     4621 taatttcgca tgacttcagc attccaacaa catctgattg accgaaccgc ccggaggtgt
     4681 catcggcatt acatttcctt cttcctccac acaagcttcg agcaggaacg gtccgtcagt
     4741 cgctatcatc tcgtcaatcg cttttgccag ctcctcgcgg gtcattaccc tgcgtgcagg
     4801 aatatcatat gccgaagcaa tcttcatata atccggattc atcatcggag taaacgaata
     4861 acgacgattg aagaacatcg cctgccattg acgaacattg cccaggaagt tattgttcaa
     4921 cagaatcatc ttcaccggag ccttttgttc catgatggta cccagttcct gcaggttcat
     4981 ctgcaagccg ccgtctccca tgaatacgca taccgtgcgg tccggacgtc caaaagtggc
     5041 accgatagct gccggaaggc cgaagcccat agtacccagg ccaccggaag taacaatgct
     5101 acgttccttg ctgtatttga aataacgggc ggacatcatc tgattctggc cgacatcagt
     5161 caccaatatc gcctcgttat gggtagcctc actcacagca cgcaccacct cacccatgct
     5221 tagcgctttt cctgccggat gtaattccgg acggattacc ttttcctctt ccacttcctc
     5281 gtattgccgg aaactgtcaa tccattcctg atggttggcg ggttccagca attgggtaac
     5341 ggcagccagt gtctctttgc aatctcccag gacagcaaca tcggtcttta cattcttatc
     5401 tatttcggca gggtcaatat caaagtggat aatcttcgcc tgcttggcat atgtttccaa
     5461 tttacccgtc acacggtcat caaagcgcat gcctacggcg ataaggacat cacatttatt
     5521 ggtattgata ttgggcccca ggttaccgtg cataccaagc attcctttgt tcaacggatg
     5581 gttcgtaggt aatgcggaaa gtcccaataa agtgcatccg gcaggcattc cggctttctc
     5641 aatgaaagca cgaagctctt gctgggcttc tcccagctcc acgccttgtc ctaccagcac
     5701 caaaggccgt tccgcaccat ttattaattc agcagccttc cgtatggcct ccggctccat
     5761 ttcgggaacg ggaagatagc tacggacata gtccacctta gtaggcgcat attctgtttt
     5821 ctccacttgg gcgtttttag caaaatccag cacgaccggt cccggacgtc cgctctttgc
     5881 cacatagaaa gcacgtgcca ctgcccaggc cacatcttct gcacgacgaa tctggtaact
     5941 ccatttcgtg ataggctgag taatgcctac caagtccact tcctgaaatg catccgtacc
     6001 caagaagttc gtccctacct ggccggcaat gacaacgata ggcgtactgt caatcatggc
     6061 atctgcaatg cccgtgatag tattggtagc acccggtcca ctggtaacca gacaaacgcc
     6121 aacctcgcct gatacacgtg caaagccttg taccgcatgg gttgctcctt gttcatggcg
     6181 aaccaagatg tggttcaatt ccttccggtg gtcgtataag gcatcgaata ccggcatgat
     6241 gctccctccc ggataaccga aaatagtctt tactccctga tgctccagag agcgcatcaa
     6301 tgcttctgcg cctgttatta gagcctcacc ccgaccctct ccttgggaga gggaggaaaa
     6361 gttactcttt ttattattat cagccatact ttatctattc attatattta aaagctcaat
     6421 agtagcttga aaaatttgtt tcattctctc ctcccctcgc tttcggaaag gggggctttt
     6481 aatcaatcag cctcacagcc cctttgtcag cggaactcac catactggca tatgctttca
     6541 atgctttgga gacttcacgg ttgcgggtta ccggagtcat aaggcgtgct gcaagctctt
     6601 catccgtcaa cttcacattg atagaacggt tcggtatatc aatttcgata atgtccccat
     6661 ccttaatctt gccgatatta ccaccggcag ccgcttcggg agaaacatgt ccgatactta
     6721 gtccggaagt accaccactg aaacgcccgt cggtaatcaa tgcacactcc ttacccagat
     6781 ggcgggattt gatataagaa gtaggataaa gcatctcttg catacccggt ccacctttcg
     6841 gcccttcgtg agtgatgacg acgacgtctc cactgaccac ctttccaccc agaataccgt
     6901 cacaagccgc atcttgtgag tcgaagactt tcgctggccc cgtaaatttc cagatactct
     6961 cgtctacacc ggcagtcttg acaacgcaac cgtcctgagc tatatttccc ttcaaaaccg
     7021 ccagaccgcc atccttgctg tatgcatgtt ccaaatcacg gatacaaccg gtcgcacggt
     7081 ccgtatcgag ttccttataa gacgcatttt gtgagccgag taccagattg aactttccgg
     7141 ctgccgcact ggagtatttc ttgattgcct ctttacatac attagagctg gtaatactat
     7201 accggtcgat tgcctctgcc aacgtcattc catccacacg gcggacattc gtatcgacca
     7261 atccgccctt ggcaagctca tccatgatgg caatgatgcc accggcacgg ttaacgtctt
     7321 gtacatgata cttttgggta ttgggagcca ccttgcataa gcagggggtc ttgcgggaga
     7381 gcatgtcaat atcgtccatc ttaaaatccg ctccggcttc gtgagccaca gccaacaaat
     7441 gaagtaccgt attagtggaa ccgcccatcg caatatccag cgtcatggca ttcaaaaatg
     7501 cctcgcgggt agcaatactg cgcgggagta cactctcatc cccttcttca taatatctaa
     7561 aggcattctc tacaatcaac ctggctgcat cctcaaatag tttcttgcga ttttcgtgag
     7621 tggctacaat cgtgccgtta ccgggcagtg ccaatccaat cgcttcattc aagcaattca
     7681 tggaattagc ggtaaacatg cctgagcagc atccgcaagt ggggcaggca tgttgctcaa
     7741 tctgtgccac ctctttatcg cccacacttt catcagcaga tttaatcatg gcatcaatca
     7801 aatccaaatg ctgtccgttc cattccccgg cttccatcgg accgcctgaa acaaacacag
     7861 tcggtatatt cagcctcata gccgccatca gcatccccgg agtaatcttg tcacagttac
     7921 tgatgcaaac catagcatct gccttatggg catttaccat atactccaca ctatcggcaa
     7981 tgatatctct tgaaggcagg gaataaagca taccgtcgtg tcccatagcg ataccgtcgt
     8041 caatggcaat cgtattgaac tccgcagcaa aacaccccag tttttcaatc tcttccttta
     8101 caaactggcc tatttcgtgc aggtgtacat gcccggggac gaattgtgta aatgaattga
     8161 ctatagcgat aatgggctta cccatctgtt ccttcttcat accattcgcc gtccacaatg
     8221 cacgggctcc cgccatgcgg cgaccttgtg tgctgaacga gctgcgtaac tgatgcttca
     8281 ttttcaaatc tccttttaat gaaaaagcct ctcccactat agtgagaaag gcttaataaa
     8341 ttatcttcta acgtacgaat acatacataa cctttctcac gctcttgatg ccaccaccac
     8401 gacgcgaata atatgcagga ctgccaggtt aatagatgta tgtaaattca taacttaatt
     8461 cttctttttt gtttcaaacg tgctgcaaag gtaagggctt ttttataatc tccaaacaaa
     8521 ttgaagaaaa aaataagata aatatgaata atcgtaagaa aatatcgccc taaaatccta
     8581 ttttatcact taacagttct aaatagaacc attcagacag ccaatgtaaa tgtattgcca
     8641 atcattgaaa ccatttaata atctgaaaat taccaaaggc tctctacatc ccgaaacaaa
     8701 taattcgtat ctttgtctct tcaaatactc aaaaaaaagt atttactaat taaataaaga
     8761 tagaaaatta atggaaacag tagaaaacaa gtacatcacc gtagcatata agctgtactc
     8821 aatcgaaaac ggagaaaaag atttcgaaga agaagcaccc gtagagcatc cttttcagtt
     8881 tatctcaggt ctgggaatga cactcgaacc ctttgaagcc cagataaaag acttgcagat
     8941 aggcgataaa ttcgacttta ccattccggc atcagaagct tatggtgaat atgacgacga
     9001 ccatgttatt gacctcccca aagaaatctt catgatagaa ggagaattcg acagcgatcg
     9061 tgtagtagaa ggtgccgtta tccccttgat gacttctgaa ggtcaacgca tcaacggaag
     9121 tgtggtagaa gtgaaggaag atatcgtcgt aatggatatg aaccatccgc tcgcaggttg
     9181 tgacttgaac ttcactggag aagtagtgga aagccgcctg gctacaaacg aagaacttgc
     9241 cgaagtcgcc cgtatgatgg gtggcggttg cggcagctgc ggttgtggtg actgtggcga
     9301 cggatgcggc gaccatgaat gtggaggcgg atgctgccac tagaagaatt aaaaatgaag
     9361 aattaaaaat gaaagaatca aactacgcaa tataagtatg ctgcatgata attctttcat
     9421 ttttaattct tcattttttt aattatttac ttgtcattat ctccaatacc aatttatccg
     9481 tttcattcat tcctttagaa ccgatttttg tcagattacg gatactctga tccacatcct
     9541 catcaataat accttctacg gaagttacac aacggttttc catggccatg atggctgaaa
     9601 gtactgcggt tgaaactccg gtagtcactt tcaatgcaca actaggtttg gcaccatcac
     9661 aaatcattcc ggtaagattg gcaatcatgt tctgtacagc atatgccacc tgctcataag
     9721 taccccccat tagccaagtt ataccgcaac tggaaccagt ggcagcaacc acacaaccgc
     9781 ataaggcgga taaccgtccc aaactctgct tgatatagat tactgtcaaa tggctcaaca
     9841 tcaaggcacg aatcaattct tcttctgatt tcccgttttc ttcggcataa atcaaaaccg
     9901 gcaacgtagc ggatatacct tgattaccgc ttcctgaatt actcatgacc ggaatcatgg
     9961 ctcctgccat acgggcatcg caagcaccgg aagtataaga aagaatatgg gaaaaaacac
    10021 tgtcccccat aaccttatgc tcgtaagtac cacgaaggat ttttcccaag ccatgtccgt
    10081 aatcaccctc aaaagagctt tctgcggcag ccttattcag acgggccgtt tcgaggataa
    10141 aacgaatttc gtccaacgga gccgtcaaag caaaatcata gactttccgc aagcttaaat
    10201 ccagcgcacc ttcctccttt tctgtgcttg caacagcctg cttgttcaac agcacttccc
    10261 cattgcgtgc catgtataca aaggaagtgt gtccacctgc aatgatagca gtggactttt
    10321 catccccgac ctcacaacaa acttcaacat aaagcttctc tttaatgcca tctttcagtg
    10381 ctatatggat gcgcttttca tctataaaac gtcttccttc ttccacggca tcgggattac
    10441 aatccttcaa tacctccagt tgatattccg atttaccgat taaggcacca agcgctactg
    10501 caataggcag cccaatcatt cctgtaccgg gaattcctac gcccatcgcg ttcttcaaga
    10561 tattggcact taaaagaacc gttatctttt ccggatgtct gcccaatact tccgcagctt
    10621 ttgccacaca caatgccaca gctataggtt ctgtgcaacc tatagcagga acgacctcgg
    10681 atttaaccaa atcaataatc tgttgtcttt ccgtttttgt catatttatt caatttagat
    10741 gcagacaaag gtaatgtatt ttattctata atagaaggaa tagaaggaat aaaataaatc
    10801 ccactattaa gacattgctt aatagtggga ttccctatct taagttgtta tcttcctgtc
    10861 taaattagat tactttttca aattcaaacc caattcaaac tttgtagttt ttgacattgc
    10921 agtcggaagg tctcccaata tagcttttat cataggacca aaactaccta atgcatccgg
    10981 atcaggaatc aattctgcaa ttgccggtcc catagcagca atagtagtca taagttcttt
    11041 atcaataaag attttcactt cttcattatt attagacaac gcataattca cagggattcc
    11101 attcttcaca agttccaaca attgagatat aacagtagtt atatcagctt tagtattagc
    11161 atcggctatt attttttcca gattcaggaa aagcaacatt ttaccattcc cctgcaattt
    11221 aaaggttgca taatctgccg gtgaagtctc ccataccgga gaaagatcta tccctgcaga
    11281 agaataagtg gccactatat taccgtcagc actcaaagta acatcctgca atacctgcgg
    11341 caatatcaca gaccccatct gtatagctaa cgacggaata gcacttaccg gcaaaaatga
    11401 tagatatgtg tcctcaggtg cctcccatgt cataaaaaca ctacctccga tcaccgaatt
    11461 attttcatcc aattcaacag ccggaacttt ccaagtacca ataaccgggt ctttaatctt
    11521 atcatcgtcg tcatcactac aagcagtgaa caaactcata gagcaaatca acgcaaataa
    11581 aaaaaacaaa ttcttt
//
