LOCUS       c00060_gnlPro..        16563 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|COODLPHK_60.
ACCESSION   c00060_gnlPro..
VERSION     c00060_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-07 20:16:36
            Original ID  :: gnl|Prokka|COODLPHK_60
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 16563
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..16563
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[3145:6703](+)"
                     /cutoff="5000"
                     /detection_rule="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /neighbourhood="10000"
                     /product="PFOR_II_pathway"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      3146..6703
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="5000"
                     /detection_rule="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /neighbourhood="10000"
                     /product="PFOR_II_pathway"
                     /protocluster_number="1"
     cand_cluster    1..16563
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /kind="single"
                     /product="PFOR_II_pathway"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..16563
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="PFOR_II_pathway"
                     /region_number="1"
                     /rules="cds(POR and POR_N and PFOR_II and EKR and Fer4_16
                     and TPP_enzyme_C)"
                     /tool="gutsmash"
     CDS             complement(573..1727)
                     /locus_tag="ctg60_1"
                     /transl_table=11
                     /translation="MALASGETNYMAPASARQMASDLALLPMWYAEAGSAVLAPSAYNA
                     DFLKTKSELLGMDVALLTEPEVADGKDRKFSPWGWDPALRKRLMTLGADQTELPSADYM
                     NILREHSHRLQAVKLLPGLRLNEYFCGESFYLSTLAECSAFVEGREACLLKAPLSGSGK
                     GLNWCKGIFTTFISGWCARVAASQGGVVGEPIYNKVEDFAMEFYADGRGRVVFAGYSVF
                     HTGGSGMYAGNDLLSDEKILQKLSAYVPQEEFIRLRTRLEEELSALFGGFYHGYLGVDM
                     MICHFPDEAPVYRIHPCVEINLRMNMGVVAWLLTDRYLAADAEGVFRIDYYPLAGQALE
                     EHRQMSASFPLSVENNRVCAGYLPLVPVTPQSRYRAFLLLTLPQ"
     CDS             1907..3112
                     /locus_tag="ctg60_2"
                     /transl_table=11
                     /translation="LPAEKQRNEMESFYRTHAYLVEHTNAPVRRDLMDEIDWSDRLIGI
                     KGTRGVGKTTFLLQYAKEKFGTDRSCLFINMNNFYFSGHSLVDFANEFQKRGGKVLLID
                     QVFKHPEWSKELRMCYDRFPSLKIVFTGSSVMRLKEENLELRDIAKSYNLRGFSFREFL
                     NLQTGMKFRAYSLEEILSTHEQIAKGVLSKVRPLDYFQDYLHHGFYPFFLEKRNFSENL
                     LKTMNMMVEVDILLIKQIELKYLSKIKKLLYLLAVDGPKAPNVSQLASDVQTSRATVMN
                     YIKYLADARLINLVYPKGEEFPKKPSKIMMHNSNLMYSIYPVKVEEQDVLDTFFVNTLW
                     KDHKVHKGDKNVSFMVDEVMPFKICAEGTKIKNNPDVTYALQKAEIGRGNQIPLWMFGF
                     LY"
     CDS             3146..6703
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: Fer4_16"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: TPP_enzyme_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: POR_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: EKR"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: PFOR_II"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: POR"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg60_3"
                     /sec_met_domain="PFOR_II (E-value: 5e-19, bitscore: 58.2,
                     seeds: 27, tool: rule-based-clusters)"
                     /sec_met_domain="POR_N (E-value: 7.1e-83, bitscore: 267.4,
                     seeds: 31, tool: rule-based-clusters)"
                     /sec_met_domain="POR (E-value: 7.8e-32, bitscore: 100.3,
                     seeds: 86, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 1.4e-12, bitscore:
                     37.2, seeds: 323, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_16 (E-value: 2.5e-12, bitscore: 37.2,
                     seeds: 227, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4 (E-value: 4.6e-08, bitscore: 22.4,
                     seeds: 528, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 2.5e-05, bitscore: 14.4,
                     seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="EKR (E-value: 1.2e-25, bitscore: 78.8,
                     seeds: 127, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTKQKKFITCDGNQAAAHISYMFSEVAAIYPITPSSTMAEYVDEW
                     AAAGRKNIFGETVLVQEMQSEGGAAGAVHGSLQAGALTTTYTASQGLLLMIPNMYKIAG
                     EFLPCVFHVSARTLASHALCIFGDHQDVMSARQTGFAMLAEGSVQEVMDLAGVAHLATI
                     KSRVPFMNFFDGFRTSHEIQKIEMLENDDLAPLIDQEALAEFRARALNPMKPVARGMAE
                     NPDHFFQHRESCNNYYEAVPAIVEEYMNEISKITGRKYGLFDYYGAEDAERVIIAMGSV
                     TEAAREAIDHLVANGEKVGMVAVHLYRPFSAKHFLAAVPKTAKSIAVLDRTKEPGANGE
                     PLYLDVKDCFYGAENAPVIVGGRYGLGSKDTTPAQIISVFENLAMPMPKNHFTIGIVDD
                     VTFTSLPQKEEIALGGEGMFEAKFYGLGADGTVGANKNSVKIIGDNTDKHCQAYFSYDS
                     KKSGGFTCSHLRFGDTPIRSTYLVNTPNFVACHVQAYLHMYDVTRGLRKNGSFLLNTIW
                     EGEELAKNLPNKVKKYFAQNNISVYYINATQIAMEIGLGNRTNTILQSAFFRITGVIPV
                     DQAVEQMKKFIVKSYGKKGEDVVNKNYAAVDRGGEYKTLTVDPAWANLPDDAKAENNDP
                     AFINEVVRPINAQDGDLLPVSAFKGIEDGTWYQGTSKYEKRGVAAFVPEWNAENCIQCN
                     KCAYVCPHASIRPFVLDAEEQKGAKFEQLKAVGKAFDGMTFRIQVDVLDCLGCGNCADI
                     CPGNPKKGGKALTMKHLESQLAEADNWTYCAENVKSKQHLVDIKANVKNSQFATPLFEF
                     SGACSGCGETPYVKLISQLFGDREMVANATGCSSIYSGSVPSTPYTMNEKGHGPAWANS
                     LFEDFCEFGLGMELANEKMRARLVKVMNEAIASDCCPAEYKEVFAEWINNMLDAEKTKE
                     LAEKIIPMVEAAKDKCNHCKQIADLQQYLVKRSQWIIGGDGASYDIGYGGLDHVIASGK
                     DVNILVLDTEVYSNTGGQSSKATPVGAIAKFAAAGKRVRKKDLGLMATTYGYVYVAQIA
                     MGADQAQTLKAIREAEAYPGPSLIIAYAPCINHGLKAGMGKSQEEEEKAVKCGYWHLWR
                     YNPALEEEGKNPFQLDSKEPNWEDFQGFLKGEVRYASVMKQYPAEAEELFKAAEENAKW
                     RYNSYKRLARENWGADTAE"
     CDS             6828..7016
                     /locus_tag="ctg60_4"
                     /transl_table=11
                     /translation="MIGFVIWIIGLILTFRAAIEIWNINAAVEKRLIAIVLIVLTSWLG
                     LLFYYFYGKERMAGWLK"
     CDS             complement(7027..7887)
                     /locus_tag="ctg60_5"
                     /transl_table=11
                     /translation="MNKIKMIAAMFIAGILLTFVSCGDNGKSKKISIAYANWSEGIAMT
                     NLAKAIFEDQGYDVKLLNADLAPIFTSISRKKADVFMDVWMPVTMEDYMKQYGDKLEVI
                     GDIYDGARIGLVVPDYVTINSIEELNAEKERFSGQIVGIDAGAGIMKATDQAIKDYGLD
                     YKLMTSSGPAMTASLKKAIDKKDWIVVTGWTPHWMFDRFKLKVLQDPKLIYGNTESIHT
                     IAWKGFSEKDPFAAELLGNIRLTDAEISSLMTALEEAQTTERQAARQWMEEHQELVNSW
                     IPEKD"
     CDS             complement(7915..8745)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) BPD_transp_1"
                     /gene_functions="transport (smcogs)
                     SMCOG1004:Binding-protein-dependent transport system inner
                     membrane component (Score: 91.7; E-value: 1.6e-28)"
                     /gene_kind="transport"
                     /locus_tag="ctg60_6"
                     /sec_met_domain="BPD_transp_1 (E-value: 2.9e-29, bitscore:
                     91.7, seeds: 81, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MINIGQYIETAINWLTEHFASFFDALSMGIGGFIDGFQHVLFGIP
                     FYITIAVLAALAWFKSGKGTAVFTLLGLLLIYGMGFWEETMQTLALVLSSTCLALLLGV
                     PLGIWTANSDRCNKIMRPVLDFMQTMPAFVYLIPAVLFFGLGTVPGAFATIIFAMPPVV
                     RLTGLGIRQVPKNVVEASRSFGATPWQLLYKVQLPLALPTILTGINQTIMMSLSMVVIA
                     AMISAGGLGEIVLKGITQMKIGLGFEGGIAVVILAIVLDRITQGMADNRKSKKK"
     CDS             complement(8742..9968)
                     /locus_tag="ctg60_7"
                     /transl_table=11
                     /translation="MSKIEIKDLYLVFGNEKQKALKMLKEGKTKSEILKATGCTVAVKD
                     ANLSINEGEIFVIMGLSGSGKSTLLRCINRLIRPTSGEVIINGTDIAKVSDKELLQIRR
                     KELAMVFQNFGLLPHRSVLHNIAFGLELQGVKKGEREQKAMESMQLVGLKGYENQMVSE
                     LSGGMQQRVGLARALANNPEVLLMDEAFSALDPLIRVQMQDELLTLQSKMKKTIVFITH
                     DLSEAIKLGDRIAIMKDGEIVQIGTSEEILTEPANAYVERFVENVDRSKIITASSVMVD
                     KPIVARLKKEGPEVLIRKMRERNLTVLPVVDSNNLLVGEVRLNDLLKLRKEQIRSIESV
                     VRHEVHSVLGDTVLEDILPLMTKTNSPIWVVNENREFEGVVPLSSLIIEVTGKDKEEIN
                     EIIQNAIEL"
     CDS             10441..11727
                     /locus_tag="ctg60_8"
                     /transl_table=11
                     /translation="MFNRAITIFLGKDNCHYTTKEKQTGTATLDDKSQVQFLSKKNPKM
                     PFFYSRRNLYMIGFLLAFIVTLLEFIRGRHQNFMVFSDATQFFWQGISPYTTEFVEAHG
                     RYFLYSPVFTVLFAPFAYLPAWLGPFAWNLFNYSLFFMAIFTLPQQFTQQQKCRMFLFL
                     LLILGQSLLSFQYNITVAYLFLFAYTLLEKDRGFLAVLLIMISGCTKVYGIFELALLLC
                     YPHVWRNFGYAVTMGIVLLALPLIKIAPADLLPYYEEWCHSLAVHQSTGAYDSFFYARP
                     IAAWTLPHFRALQIGMLGLLTLLFLGNFRKWSSFAFRAQALGILMGWVVLLSDSAEKHT
                     YIIALAGFMLWYWSRPTRTATDKILFWCCFVLLCIVPIDIFVPVPIRDFITRTLWLHVW
                     VFFIVWIRMIWLTFLASFIHPRATNVLSD"
     CDS             complement(11690..12022)
                     /locus_tag="ctg60_9"
                     /transl_table=11
                     /translation="MKDYKVDKESFSESFRKEVYEVVSQIPVGKVSTYGGIALLLGAPQ
                     CSRMVGRALKEVPDELSIPCHRVVNSAGRLVPGWVEQKQLLLAEEVSFKANGCVNLKEH
                     LWHVDE"
     CDS             complement(12050..14803)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peripla_BP_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1042:Periplasmic binding proteins and sugar binding
                     domain of LacI family (Score: 64.3; E-value: 4.2e-20)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg60_10"
                     /sec_met_domain="Peripla_BP_1 (E-value: 7.4e-21, bitscore:
                     64.3, seeds: 6, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKTMRYLKWMLVLFCLIGMTACRQDTPRFRIGVAQCSDDSWRHKM
                     NDEILREAMFYNGVSVEIRSAGDDNSKQAEDVHYFMDEGVDLLIISANEAAPMTPIVEE
                     AYQKGIPVILVDRKILSDKYTAYIGADNYEIGRSVGNYIASSLKGKGNIVELTGLSGST
                     PAMERHQGFMAAISKFPDIKLIDKADAAWERGPAEIEMDSMLRRHPKIDAVYAHNDRIA
                     PGAYQAAKMAGREKEMIFVGIDALPGKGNGLELVLDSVLDATFIYPTNGDKVLQLAMDI
                     LEKKPYPKETVMNTAVVDRTNAHVMQLQTTHISELDKKIETLNGRIGGYLSQVATQQVV
                     LYGSLIILLLVAGLLLVVYKSLRSKNRLNKELFKQKQQLEEQRDKLEEQRDQLIQLSHQ
                     LEEATHAKLVFFTNISHDFRTPLTLVADPVEHLLADKTLSGDQHRMLMLIQRNVNILLR
                     LVNQILDFRKYENGKMEYTPVTVDVLSSFEGWNESFQAAARKKHIHFSFDSMPDTDYHT
                     LADMEKLERIYFNLLSNAFKFTPENGKIAIRLSSLSKEDKRWIRFTVANTGSMISAEHI
                     RNVFDRFYKIDMHHTGSGIGLALVKAFVEMHGGMISVESDEKQGTVFTVELPVQSCEAV
                     AAEPDTTLVSADSRTTDVLLAEEEELEKGYDSSKSSVLIIDDNEDIRSYVHTLLHTDYT
                     VIEAADGSEGIRKAMKYVPDLIISDVMMPGIDGIECCRRLKSELQTCHIPVILLTACSL
                     DEQRIQGYDGGADSYISKPFSSQLLLARVRNLIDSHRRLKQFFGDGQTLAKEDVCDMDK
                     DFVERFKSLIEEKMGDSGLNVEDLGKDMGLSRVQLYRKIKSLTNYSPNELLRIARLKKA
                     ASLLASSDMTVAEIGYEVGFSSPSYFAKCYKEQFGESPTDFLKRKG"
     CDS             complement(15136..16254)
                     /locus_tag="ctg60_11"
                     /transl_table=11
                     /translation="MKHISNFLRSKSWNVFLFLYLALPLFAQKEYKIDQVSVVNVGDGR
                     LLFRELKTEKALNGEHRIIDGYHSAYVLASFKDGFYDGGYKEYVDNILITEGSYKEGRK
                     DGLFKINSKFDGKLKEEKSYKEGKLDGTSKSYFTTGKVESERNFRMGKEHGKQLSYESD
                     GTLRKEHNYKDGKQVGKQYTFLKGTYDLYETVYFNEEGLQDGEYSSVFTFGSPRILGSY
                     KNGKKNGRWTTFAESGDTLMIETYLDGKEDGLHVSFANGSGVRQKEYYMKNDRKDGLYR
                     EYNLENGELRYEATYQAGRLHGKERRLIVSNRFDYWETSTYVNGRQNGPFEARYVKNDQ
                     LRECGEYKNGRRVGRWKRYTIDGKLEKEWDEN"
ORIGIN
        1 gtaaactaat tcagttataa caaacgaagt tgtcaactaa aaccagtaca catcaccaat
       61 tccaatttag cagtatcttc aaagagtttc cattgcttga aaccagagtt tcatcggtgt
      121 gaaactgtag tttcatcggt gagaaactag agtttcatac gcttgaaact ttagttccaa
      181 acgctcgaaa ctatctgaaa ctactgttga tttgattgac ttaaccgcat gttccaatca
      241 cattgaacgc atcagctact tcaatagtac tgctctctct gaaaacatta aatcatatat
      301 cagtcaataa tacataaatt atcagtcctt aatacttgat ttctcaatta ttaatatctg
      361 agaaatcaaa cgttaacagt tgagatatca gatattaaca tcctgtaaat caaagaataa
      421 cacagtaaaa acggtattta tcaggacgat gcagagtgag agcaagtcct tgctctcact
      481 ctgctaccac tggatctcta acagctaaaa catcgatgaa taaagggata cagacgaact
      541 gttagagcat gagagcaaaa gcactatctt tttcactggg ggagagtaag caaaagaaac
      601 gcacgatacc ggctttgagg cgtcaccggt actaacggca aatatccggc acacacccga
      661 ttattctcta cggacaaagg gaacgaagcc gacatctgcc gatgttcctc caaagcctga
      721 ccggctaaag gataataatc aatccgaaaa actccttccg catccgcagc caaataacga
      781 tccgtcaaga gccatgccac cacccccata ttcattcgca gattaatttc gacacaagga
      841 tgaatccggt aaacaggcgc ttcatccgga aaatgacaaa tcatcatatc cactcccaag
      901 tatccatgat aaaagccacc gaacaaagct gacaattctt cttccaaacg agtccgcagc
      961 ctgataaatt cttcttgtgg cacataagcc gatagtttct gcagaatctt ctcgtcagac
     1021 agcaagtcat tccctgcata catcccactc ccacccgtgt ggaagaccga atatccggca
     1081 aaaacaaccc ttcctctccc gtcagcataa aactccatag cgaaatcttc caccttatta
     1141 tatataggtt cgcctaccac cccaccctga gaagcagcga cacgggcaca ccaaccggaa
     1201 ataaaagtag taaatatgcc tttacaccaa ttcaatcctt tcccgcttcc ggaaagcgga
     1261 gcttttaaca agcacgcttc ccgcccttcg acgaacgcac tgcactccgc caaagtactc
     1321 aaataaaaag attctccaca gaagtattca ttcaaccgca acccaggcaa caactttacc
     1381 gcctgcagac gatgcgaatg ctctctcaga atattcatat aatccgcaga aggcagctcc
     1441 gtctgatctg cccccaatgt catcaaacgc ttccgcaaag cagggtccca cccccacgga
     1501 gagaacttcc ggtctttacc gtcagccact tccggttccg tcaacaaggc cacatccatg
     1561 cccaaaagtt cactctttgt tttcaggaag tccgcattat aagcagacgg tgcaagcacc
     1621 gcacttcccg cttcggcata ccacatagga agcaacgcca ggtcactcgc catctgtcgg
     1681 gcggaagccg gcgccatata gttcgtctca ccgcttgcca acgccatatc atgctccgga
     1741 ttgaatatat aaacaggtct tttcgtcatg tcaaagatgg attcaacaca ttattctgca
     1801 aatatataca ggaaataatc aggaacttac acaataaaga gaaacttata aattaaagca
     1861 catttttgct atctctactt tgcaaatcct aaaaaaagca ctatatttgc cagccgaaaa
     1921 acaaagaaac gaaatggaat cattctatcg cacacacgcc tacctcgttg agcacaccaa
     1981 tgcccccgtt cgccgcgatc ttatggacga gatcgactgg agtgaccgtc tgattggtat
     2041 caaagggaca cgtggcgtag gaaaaaccac tttcctcctg cagtacgcca aagagaaatt
     2101 cggcaccgac cgttcctgtc tgttcatcaa tatgaacaac ttttatttct ccggtcacag
     2161 ccttgttgac ttcgccaacg agtttcagaa acgtggcgga aaagtactgc tgatcgacca
     2221 ggtgttcaaa catcccgaat ggagcaaaga gctacgaatg tgctatgacc gtttccccag
     2281 cctgaagatt gtcttcaccg gttcttccgt catgcgactc aaagaggaaa acctcgaatt
     2341 gcgtgacatt gcgaaaagtt ataacctgcg cggattctct ttccgtgaat ttctgaacct
     2401 gcagacagga atgaaattcc gggcatacag cctcgaagaa atcctcagta cacatgaaca
     2461 gatagccaaa ggagtacttt ccaaagtacg accgctggat tattttcagg attacctgca
     2521 tcatggtttc taccctttct tccttgaaaa acgtaatttc tcggagaatc tgctgaaaac
     2581 aatgaacatg atggtagaag tggatatctt gctgatcaaa caaattgagc tgaaatatct
     2641 ttcaaagata aaaaaattac tatatttgtt ggctgtggac ggaccgaaag ctccgaacgt
     2701 gagccaactg gcaagtgacg tacagacatc ccgcgctacg gtaatgaact atatcaagta
     2761 tctggcagac gcgcgtctga ttaatctggt ttacccgaaa ggagaagaat tcccaaagaa
     2821 accgtcaaag attatgatgc acaactctaa cctgatgtac tccatttatc cggtgaaagt
     2881 ggaagaacag gatgtacttg acacgttctt cgttaacact ttatggaaag accataaggt
     2941 acataaagga gataaaaacg tctctttcat ggtagacgaa gtgatgccgt tcaaaatttg
     3001 tgcggaaggt acaaaaataa agaataaccc ggacgtgacg tatgcgttgc aaaaggctga
     3061 gataggccgc ggcaaccaaa tacctctctg gatgttcgga ttcttatact aaaaagattt
     3121 atttacttaa atatttaatt tagttatgac taaacagaag aaattcatca catgtgatgg
     3181 taaccaagct gcagcacata tctcgtatat gttctctgaa gtagcagcta tctaccccat
     3241 cactccttct tcgactatgg ctgagtacgt agacgaatgg gctgccgcag gacgtaagaa
     3301 catcttcggc gaaacagtat tggtacagga aatgcaatct gaaggtggtg ctgccggtgc
     3361 agttcacggt tctcttcagg ctggtgcatt gactactact tacactgctt ctcagggtct
     3421 tcttttgatg atccctaaca tgtacaagat tgccggtgaa ttcttgcctt gtgtattcca
     3481 cgtttctgct cgtacactgg cttctcacgc attgtgtatc ttcggtgacc atcaggacgt
     3541 aatgtcagct cgtcaaaccg gcttcgctat gttggcagaa ggttctgtac aggaagttat
     3601 ggatttggca ggtgttgctc atctggctac tatcaaatca cgcgttccgt tcatgaactt
     3661 cttcgatggt ttccgtactt ctcacgaaat ccagaagatc gaaatgttgg aaaacgacga
     3721 cctcgctccg ctgatcgacc aggaagcttt ggctgaattc cgtgcccgtg cactgaatcc
     3781 gatgaagccg gttgcccgtg gtatggctga aaaccccgac cacttcttcc aacatcgtga
     3841 atcatgcaat aactactatg aagcagttcc tgctatcgta gaagaataca tgaacgaaat
     3901 ttccaagatc acaggccgca aatacggttt gttcgattac tacggtgcag aagatgcaga
     3961 acgcgtaatt atcgcaatgg gttctgtaac tgaagctgcc cgcgaagcta tcgaccactt
     4021 ggtagcaaac ggcgaaaaag taggtatggt tgccgtacac ttgtatcgtc cgttctctgc
     4081 taaacacttc ctggctgctg tacccaagac tgcaaagagc atcgcagtgc ttgaccgtac
     4141 aaaagaaccg ggtgctaacg gcgaacctct ttaccttgac gttaaagact gcttctatgg
     4201 cgcagaaaat gctcctgtta tcgttggcgg tcgctacggt ctgggttcaa aagatacaac
     4261 tccggcacag atcatctctg tattcgaaaa cttggctatg ccaatgccga agaaccactt
     4321 cactatcggt atcgtagacg acgttacgtt cacttctctt cctcagaaag aagaaatcgc
     4381 tctgggcggt gaaggtatgt tcgaagctaa attctacggt ctgggtgctg acggcacagt
     4441 aggtgccaac aagaactctg ttaagattat cggtgacaac accgacaaac actgtcaggc
     4501 ttacttctct tacgactcca agaagtcggg tggtttcact tgttctcact tgcgtttcgg
     4561 tgacactccg atccgttcta cttacttggt aaatactccg aacttcgttg cttgtcacgt
     4621 tcaggcttac ctgcacatgt acgacgtaac acgtggtttg cgtaagaacg gttctttctt
     4681 gctgaacacc atctgggaag gcgaagaact ggctaagaac ctgcctaaca aggtgaagaa
     4741 atactttgca cagaacaaca tctctgtata ctatatcaac gcaactcaga ttgcaatgga
     4801 aattggtttg ggcaaccgta ccaatacaat ccttcagtct gcattcttcc gtatcacagg
     4861 cgtaatccct gtagatcaag ctgttgaaca gatgaagaaa ttcatcgtta agtcttacgg
     4921 caagaagggt gaagacgttg taaacaagaa ctatgctgct gtagaccgcg gtggtgaata
     4981 caagactcta actgttgatc ctgcttgggc taacctgccg gatgatgcaa aagcagaaaa
     5041 caatgatcct gctttcatca acgaagtagt tcgtccgatc aatgcacagg acggtgactt
     5101 gctgccggta tctgcattca agggtatcga agacggtact tggtatcaag gtacttccaa
     5161 atacgaaaaa cgtggtgtag ctgcattcgt tcccgaatgg aatgctgaaa actgtattca
     5221 gtgtaacaag tgtgcttacg tttgtcctca cgcttctatc cgtccgttcg tactcgatgc
     5281 tgaagagcag aagggtgcta agttcgagca actgaaagct gtaggtaaag cattcgatgg
     5341 tatgacattc cgtattcagg tagacgttct cgactgtctg ggttgcggta actgtgccga
     5401 catctgtccg ggtaatccga agaagggtgg caaggcattg accatgaaac accttgaaag
     5461 ccagttggcc gaagctgata actggactta ctgcgctgaa aacgtgaaga gcaaacaaca
     5521 cctggtagac atcaaggcta acgtgaagaa ctctcagttc gcaactccgt tgtttgagtt
     5581 ctcaggcgct tgctccggtt gtggtgaaac tccgtacgtg aaactgattt ctcagttgtt
     5641 cggtgaccgt gaaatggttg ctaacgctac aggatgttct tctatctact ccggttcagt
     5701 tccttctact ccgtacacta tgaacgaaaa gggtcacggt cctgcatggg ctaactcctt
     5761 gttcgaagac ttctgtgaat ttggtctggg tatggaactg gctaacgaaa agatgcgtgc
     5821 ccgtctggtg aaagtaatga acgaagctat cgcttctgat tgctgcccgg ctgaatacaa
     5881 agaagtattt gctgaatgga tcaacaatat gctggatgca gaaaagacta aggaactggc
     5941 cgaaaagatc attccgatgg tagaagctgc taaagataaa tgcaaccact gcaagcaaat
     6001 cgctgatctg caacaatatc ttgttaaacg cagccaatgg atcatcggtg gtgacggtgc
     6061 ttcttatgat atcggttacg gtggtcttga ccatgtaatc gcttccggta aggacgttaa
     6121 catccttgta ttggatactg aggtttactc taacacaggt ggtcagtctt ctaaagctac
     6181 tccggtaggc gctatcgcta agtttgctgc tgcaggtaag cgtgtacgta agaaagacct
     6241 cggtctgatg gctactactt acggttatgt atatgttgct cagattgcta tgggtgctga
     6301 ccaggctcag actctgaaag ctatccgtga agctgaagca tatccgggac catcactgat
     6361 catcgcttac gctccatgta tcaaccacgg tctgaaagcc ggtatgggta agagccagga
     6421 agaagaagaa aaggctgtta agtgcggtta ctggcacttg tggcgttaca accctgcttt
     6481 ggaagaagaa ggcaagaatc cgttccaact ggatagcaaa gaacctaact gggaagactt
     6541 ccaaggtttc ttgaagggtg aagttcgtta cgcttctgta atgaaacaat atcctgctga
     6601 agctgaagaa ctgtttaaag ctgctgaaga aaacgctaaa tggcgttaca acagctacaa
     6661 acgtcttgcc agagaaaact ggggagctga tacagctgaa taataagtag aaatactttg
     6721 tacataataa aaggcaggaa ttctggaaac agattcctgc cttttttgtt tatatcttag
     6781 aagtaacgat tacttctcac gaagatattc attaaaactc taaagatatg atcggatttg
     6841 ttatttggat tatcggtttg atactgactt tcagagctgc catagagatt tggaatataa
     6901 atgcggctgt agagaaaaga cttatagcga ttgtattaat cgttcttacc agctggctgg
     6961 gactactttt ctactacttc tatggtaaag aaagaatggc gggatggttg aagtagtgtt
     7021 tgcatatcaa tctttctcag gaatccaact gttcaccagt tcctgatgtt cttccatcca
     7081 ttgacgggca gcctgtcttt ccgttgtctg cgcctcttcc agagcagtca ttaaggagct
     7141 gatttccgca tctgtcagac gaatgttgcc caaaagttcg gcagcaaaag ggtctttctc
     7201 gctaaaacct ttccatgcta tggtatgaat ggattccgta tttccatata tcagcttcgg
     7261 gtcctgaaga actttcagct tgaaacggtc gaacatccag tgaggcgtcc atcccgtcac
     7321 gacaatccag tctttcttat caatcgcttt ctttagggaa gcagtcatgg caggtccgct
     7381 cgaagtcatc agtttataat ccaatccata gtctttgatg gcctgatcgg tagctttcat
     7441 aataccggct ccggcatcaa taccgacaat ctgaccggag aaacgttcct tttccgcgtt
     7501 cagttcttcg attgagttga tcgtaacgta atccggaacc accagcccga tacgggcacc
     7561 atcataaata tccccgataa cttcgagttt atccccgtat tgtttcatat aatcttccat
     7621 agtgacaggc atccagacat ccataaatac gtctgctttc ttacgggaga tagaggtaaa
     7681 tataggtgca aggtcggcat tcagcaactt tacatcgtac ccctgatctt caaaaatcgc
     7741 tttggcaagg tttgtcattg caataccttc cgaccagttg gcataagcga tacttatctt
     7801 cttactcttt ccgttgtctc cgcaggaaac gaaggttaag agtatgccgg caataaacat
     7861 tgccgcaatc atttttatct tattcattga ttattccttt ctttggtgtg attcttattt
     7921 ctttttactt tttctgttat ctgccatacc ctgagtgatg cggtccagca cgatcgccaa
     7981 tatcacgact gcgataccgc cttcaaatcc gagtccgatt ttcatttggg tgataccttt
     8041 cagcacgatt tctcccaatc ctccggcaga aatcatggca gcaatcacta ccatcgaaag
     8101 tgacatcatg atcgtctggt tgattcccgt cagaatagta ggcaacgcca aaggcaattg
     8161 caccttataa agaagctgcc agggagtagc tccaaaagag cgggaggctt ctactacgtt
     8221 tttaggaacc tgacgaatgc ccagaccggt cagacgaacc acaggaggca ttgcaaagat
     8281 gatggtggca aaagctcccg gcacagttcc caatccgaag aatagaacgg caggaatcag
     8341 atagacaaag gcaggcattg tctgcataaa gtcgaggaca gggcgcatta tcttgttaca
     8401 acgatcactg ttggcagtcc agattcccaa cggaacgcct aaaagcaatg ccagacaagt
     8461 ggaagaaagt accaatgcca atgtctgcat cgtttcttcc caaaagccca tgccgtaaat
     8521 aagcaataaa cccaagaggg taaatacggc tgtcccctta cccgacttaa accaggcgag
     8581 cgcagccagc actgcaattg tgatataaaa aggtattcca aacagtacgt gctgaaaacc
     8641 gtctatgaat cctccgatcc ccatgctgag agcatcaaaa aaggaagcaa aatgttctgt
     8701 gagccaatta atggcagtct ctatatattg tccgatattt atcataattc tattgcgttt
     8761 tgaatgattt cattaatttc ttctttatct tttcccgtta cttcgatgat caatgaggaa
     8821 agtggcacta cgccttcaaa ctcccgattc tcatttacga cccagattgg cgagttcgtt
     8881 tttgtcatca acggaagaat atcttccagc accgtatcac ccagcactga atgaacttca
     8941 tgccttacta cggactcgat ggagcggatt tgctcttttc gtagtttcag caagtcattc
     9001 aaccgcacct ctcctactaa cagattattg gaatcgacta ccggaagaac ggtcagattc
     9061 cgttcgcgca tcttacggat cagcacctcc gggccttctt tcttcaaacg tgccactatg
     9121 ggtttatcta ccataacaga ggaagctgtt ataatcttgc ttcgatctac attctccaca
     9181 aatcgttcta cataagcgtt ggcaggttcg gtcaggattt cttccgatgt accgatttgt
     9241 acaatttctc catccttcat gatagcaatc cggtcaccca atttaatcgc ttcactcagg
     9301 tcgtgagtaa taaagacaat cgtttttttc atcttcgact gcaaagtcag cagttcatcc
     9361 tgcatctgca cacggatcaa aggatcgagt gccgagaagg cctcatccat caacaggact
     9421 tcgggattat tggccaaagc ccgcgccagc ccgacacgct gctgcatccc acccgacagt
     9481 tcacttacca tctgattctc gtagcctttc agccccacca gttgcatgct ttccatcgct
     9541 ttctgctccc gttctccctt ttttactccc tgtagttcga gcccgaaagc tatattatgc
     9601 aagacagaac ggtgaggaag cagaccgaag ttctgaaaga ccatagccag ttctttccgg
     9661 cgaatctgca acagttcctt atccgacact ttggctatgt ctgttccatt gataatcact
     9721 tctccggaag tagggcgtat caaacggttg atgcagcgga gtaaagtgga ctttccacta
     9781 ccggacagcc ccataatgac gaatatttcg ccttcattaa tggaaagatt cgcatctttc
     9841 accgcaactg tacatccggt cgctttcaat atttcacttt ttgttttacc ttctttcaac
     9901 atcttcaaag ccttctgctt ctcattgcca aaaaccagat agagatcttt aatttctatt
     9961 ttactcatac aataaaatgg tttaggttat taaaataata tacacagcaa gacaagaaca
    10021 aacgataaca ggaatctttc tttatatcgt ataaagttct gatttaaata cgggacaaat
    10081 aacaatgaat cccgaaataa ttaataaaat gattattgac agactgagta attaaaaaag
    10141 gaatagaatt tgataagata atcctttcaa cgaatagcaa aaaatagcat ttttatgtat
    10201 aaaaacagcc tgttccagta tcttgctggc acaaagatac aaaaaacgga ttaaacatac
    10261 aaattatatt caaaatccgg ggcatacaga gggctttatt tgtaatgata tggaaagttt
    10321 ccgggtaata ttcccctatc actcagcaaa atagaacaaa ccggcagata aatataaaat
    10381 aagtttgaat atttcactta aacaccgtat atttggcgtc aataactaaa ctagatttat
    10441 atgttcaaca gggctattac aattttcctg gggaaggata attgtcatta cacaacaaaa
    10501 gaaaaacaaa caggtactgc cacactagac gacaaaagcc aagtacagtt ccttagtaaa
    10561 aagaacccca aaatgccgtt tttctatagc cggcggaatc tctacatgat aggtttcttg
    10621 ctcgctttta tagtgactct gctcgaattt atacgaggac ggcatcaaaa ctttatggtc
    10681 ttctcggacg ctactcaatt cttctggcaa ggcatcagcc catacacaac tgaatttgta
    10741 gaagctcacg gacgctactt cctttattct ccagttttca cggtattgtt cgctccgttt
    10801 gcgtatctgc ctgcatggct gggacctttc gcgtggaatc tattcaatta ttcgctgttc
    10861 tttatggcga tcttcacgct gccccaacaa ttcacccagc agcagaaatg ccgtatgttc
    10921 ctttttctgt tactgatttt aggacaaagt ttactttcat ttcagtataa cataacggta
    10981 gcctatttat tcttattcgc ctatacgtta ttggaaaaag accgtggatt tctggctgtt
    11041 ctgttaatca tgatttcggg atgtaccaaa gtatatggaa ttttcgaact ggcattgttg
    11101 ctgtgctatc ctcacgtatg gcgtaacttt ggctatgccg ttacaatggg cattgtattg
    11161 cttgcattac cgttaatcaa aatagctcct gcagatttgc tcccctatta tgaagaatgg
    11221 tgccatagtc ttgctgttca tcagtccacc ggagcttatg attcattttt ctatgcccgc
    11281 cccattgcag catggacatt gccacacttc cgtgcacttc agataggaat gctcggcttg
    11341 ctgactctgc tctttttggg gaatttccgc aaatggtcgt cttttgcctt ccgtgcccag
    11401 gctttgggca ttctcatggg ctgggtagta ttactgagtg actccgccga gaagcatacc
    11461 tatattatcg cattggcagg tttcatgctc tggtattgga gcagaccaac acgtaccgca
    11521 acagacaaga ttctattttg gtgctgtttt gtgctgttat gtatcgttcc tatcgacata
    11581 ttcgtccctg tacccatcag agatttcatt accaggacct tatggcttca tgtatgggtt
    11641 ttctttattg tatggatacg gatgatatgg cttaccttcc ttgcatcctt cattcatcca
    11701 cgtgccacaa atgttctttc agattaacgc atccgttagc tttgaaagaa acttcttctg
    11761 ccagcaagag ttgtttttgt tccacccaac cgggcaccag ccttccggcg gaatttacaa
    11821 ctctatggca gggaatggat aattcatccg gcacttcttt caatgcacgt cccaccatcc
    11881 gcgagcattg gggtgccccc aacagcaaag caatacctcc ataagtagat acttttccca
    11941 caggtatctg ggatacgact tcgtacactt ccttccgaaa ggattcagaa aagctctctt
    12001 tatctacttt ataatctttc atatatccct ctttacgatc acaatgaaat catcctttcc
    12061 ttttcaggaa atctgtcggg ctctctccaa actgctcttt atagcacttg gcgaaataag
    12121 aaggtgaact gaaaccgact tcataaccaa tctccgctac ggtcatgtcc gaagaagcaa
    12181 gcaaagaagc tgccttcttc aaacgggcga tacggagcaa ttcattcgga gagtagttag
    12241 tcaatgattt aatcttgcgg taaagctgca cacggcttag tcccatgtct ttgcccaagt
    12301 cctccacatt caaaccggag tctcccattt tctcttcaat caatgacttg aatctttcta
    12361 caaaatcctt gtccatatcg cagacatctt cttttgccaa tgtctgcccg tcaccaaaga
    12421 actgtttcag acgacggtga gaatcaatca gattgcggac acgtgccaac aacagctgtg
    12481 aactgaacgg ctttgaaata taagaatccg caccaccgtc atatccctga atacgctgtt
    12541 cgtccagtga acacgctgtc aacagaataa ccggaatatg acaggtctgt aactcacttt
    12601 tcagccggcg gcaacattca atgccatcaa tgcccggcat catcacatca gaaatgatca
    12661 ggtccggaac atacttcata gccttacgga ttccttcgga gccgtctgcc gcttcaatca
    12721 ccgtatagtc tgtatgcaac agcgtatgaa catacgaacg gatatcctca ttatcatcaa
    12781 taatcaatac ggacgatttg gaagagtcat atcctttttc cagttcttcc tcttctgcca
    12841 atagaacatc tgttgtacgg gaatccgcag aaacaagggt ggtatccggt tcggcagcaa
    12901 cagcctcgca agactgtaca ggcagttcaa cggtaaagac cgtgccctgt ttctcatcgc
    12961 tctctacaga gatcatacca ccgtgcattt ctacgaaggc ttttaccaat gccagtccga
    13021 ttcccgaacc ggtatggtgc atatcgatct tatagaaacg gtcgaataca ttgcggatat
    13081 gttcggcaga aatcatggaa ccggtatttg ccaccgtgaa acgtatccat cgcttgtcct
    13141 ctttactaag ggaagacaga cggatggcta ttttcccgtt ttccggtgta aacttaaagg
    13201 cattggacag gagattgaaa taaatacgtt ccagcttctc catgtctgcc agtgtatgat
    13261 aatccgtatc cggcatacta tcaaaagaaa aatggatatg cttcttacgg gctgccgcct
    13321 gaaaagactc attccatcct tcgaaagaag aaaggacatc caccgtaacc ggagtatatt
    13381 ccatcttgcc gttttcatat ttacggaaat ccagaatctg attgaccaga cgcagaagga
    13441 tgttcacatt ccgctgaatc agcatgagca tccggtgctg atctccgctc agtgtcttgt
    13501 ccgccaacaa atgttctacc ggatcggcaa ccaatgtcaa cggagtacgg aagtcgtgag
    13561 aaatattggt gaagaatacc agcttggcat gagtagcttc ttccagttga tgagaaagtt
    13621 gtatcaattg gtcacgctgt tcttccagtt tgtcacgttg ctcttccaat tgttgcttct
    13681 gcttaaaaag ttctttattc aagcgattct ttgagcggag tgatttataa acgaccaata
    13741 ataagccggc taccaataaa aggataatca gactgccgta taaaacgacc tgttgtgtag
    13801 ctacctgaga gagatagcca ccgatacgtc cgttgagcgt ttcaatcttt ttgtcgagtt
    13861 cggaaatgtg tgtggtctgc aactgcatga cgtgtgcgtt ggtacggtcc acaacagcgg
    13921 tattcatcac cgtttctttg ggatagggtt tcttctccag aatatccata gccagttgca
    13981 gtaccttatc accattggtc ggatagataa aggtggcatc cagcacactg tccagaacca
    14041 gttccagtcc gtttccctta cccggcaagg catctatgcc gacaaaaatc atttccttct
    14101 cccgccctgc catctttgct gcctgatagg cacccggagc gatacggtca ttatgggcat
    14161 acacagcatc aatcttagga tgcctccgaa gcatactatc catttctatc tctgccggac
    14221 cacgttccca agcagcatcc gctttatcaa tcagctttat atccgggaat ttactgatgg
    14281 cagccataaa tccctgatgc cgttccattg caggagtcga accgctcaat cctgtcagtt
    14341 ctactatatt tcccttccct ttcagactgg aggcaatata gtttcctacc gaacgaccaa
    14401 tttcataatt atcggctccg atataggcag tatatttatc cgaaagaatc ttccggtcta
    14461 caagaataac ggggatgcct ttctgataag cttcttctac aatcggagtc ataggagcag
    14521 cttcgttagc ggaaataatc agcagatcga ctccttcgtc cataaaataa tggacatctt
    14581 ccgcctgctt actgttatca tcccctgccg aacggatttc caccgaaaca ccattataaa
    14641 acatcgcttc ccgaagaatc tcatcattca tcttatgtcg ccatgaatca tcgctgcatt
    14701 gagccacccc aatacgaaaa cggggtgtat cctgccggca agccgtcatc ccgattaaac
    14761 aaaacagcac cagcatccac ttcagatatc tcatcgtctt catccatctc atcatttcgt
    14821 agttctttct gtaatccaat taagaacaaa aataagaaat aatactgtaa agttctctaa
    14881 cttcagctat ttattattct aaaaagaagg aaagcagtcc tctttcagac catcggaaag
    14941 tattaacaaa agtataaagc gtaaaacaaa cacttaatca atgttataaa acatagcgtt
    15001 ttacttggat aatttgcaga tttcacagaa gtccgtatct ttgcactgtg tttttcatag
    15061 tattagattt aaggttaaca aaggttggag caaggcgttg ctcctttttt tatgccctga
    15121 cctttcatct accggttagt tttcatccca ttccttttcc agtttaccat caatagtgta
    15181 gcgtttccat cgtcctacac ggcgaccatt cttatattcc ccacattcac gaagctggtc
    15241 attctttaca taacgagctt cgaacggtcc gttctgcctt ccgttcacat aggtagaagt
    15301 ttcccaataa tcaaagcggt tgctcactat cagccgtcgt tccttgccat gcaatctgcc
    15361 ggcctgatag gtagcttcat atctcaattc accattttcc agattatatt cacggtataa
    15421 accgtcttta cgatcgttct tcatataata ttctttctgc cttaccccac ttccgttggc
    15481 aaatgagaca tggagtccat cttcttttcc atccagatag gtttcaatca tcagcgtatc
    15541 tccgctttca gcaaaagtag tccaccgacc attcttcttt ccattcttat aactacccag
    15601 tatacgtggc gagccaaacg taaacacgga cgaatattca ccgtcctgca aaccttcttc
    15661 attgaaataa acggtctcat acaaatcata tgtacctttc agaaaagtat actgtttgcc
    15721 tacctgcttc ccgtccttgt aattatgctc tttccgcaaa gtaccgtcag attcgtacga
    15781 cagttgcttc ccgtgctctt tccccatccg gaagtttctt tcactttcca cttttccggt
    15841 agtaaagtaa cttttgctcg taccgtccag cttaccttcc ttataggact tttcttcttt
    15901 cagcttaccg tcaaacttgg agttaatctt gaagaggcca tccttccgcc cttctttata
    15961 acttccttcc gttattaata tattgtccac atattctttg tatccgccat cataaaaacc
    16021 atctttaaaa gatgccagca cataggcgga atgataacca tctatgatgc gatgttcgcc
    16081 attcaatgct ttttccgttt tcagttcccg aaacaacagt ctgccatcgc ctacattgac
    16141 aacggatacc tgatcgatct tatattcctt ttgcgcaaac aaaggaagag caagatataa
    16201 aaacaaaaat acgttccagc tttttgatct gaggaagttt gaaatgtgtt tcataaagta
    16261 gttttctctt tttaatttat tatttaaaga cctgccgcaa agataggcaa tcggcttata
    16321 aaacaaggaa agaaagaggg ggacaattag agaaaagaac atctgttatt atcattctaa
    16381 taattaacag attaagtagt aaatcaaaac acagggaagg gggacattta ctgaaataag
    16441 aaacagaaaa gaagatgtgt caaaagcaac taaattcccc tccttcagga aggaggagag
    16501 tttagttgct tttgacacat ttacatttgc agtattaaat atcacaacaa aatataagtg
    16561 tat
//
