LOCUS       c00001_gnlPro..        12875 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|DGIBHAJF_1.
ACCESSION   c00001_gnlPro..
VERSION     c00001_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-05 14:14:13
            Original ID  :: gnl|Prokka|DGIBHAJF_1
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 12875
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..12875
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[2582:8572]"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      2583..8572
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
     cand_cluster    1..12875
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /kind="single"
                     /product="TPP_AA_metabolism"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..12875
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="TPP_AA_metabolism"
                     /region_number="1"
                     /rules="(TPP_enzyme_C and not (PFL-like or PFL_6_pcresol or
                     PFL_9_tma or Gly_radical or Gly_430_pcre or Gly_8-9_TMA or
                     PFL_acetate1 or PFL_acetate2 or Gly_radical_scatole or
                     PFL_proline or PFL_toluene) and minimum(2, [ALS_ss_C,
                     AlaDh_PNT_C, Arginase, BKACE, BcrAD_BadFG, Beta_elim_lyase,
                     CPSase_L_D2, Cys_Met_Meta_PP, ELFV_dehydrog, GRDB,
                     Glu_syn_central, Glu_synthase, Gly_reductase, HAAA1, HG2B1,
                     HG2B2, HGD-D, HleuD1, HleuD2, HleuS1, HleuS2,
                     Homoserine_dh, ILVD_EDD, IlvC, Lactoyl-CoA1, Lactoyl-CoA2,
                     Lyase_aromatic, MAAL_C, OKR_DC_1_5_lysine,
                     OKR_DC_1_5_ornithine, OKR_DC_1_7_arginine, OKR_DC_1_C,
                     OTCace, PALP, Proline_reductase, Sacchrp_dh_C, TPL,
                     Thr_dehydrat_C, TnaA, Urocanase]) and not (POR or POR_N or
                     PFOR_II))"
                     /tool="gutsmash"
     CDS             2..676
                     /locus_tag="ctg1_1"
                     /transl_table=11
                     /translation="YTAETIWAQLFSAPDSYSGMHNESSPIGSQTALYLPTDAFIASFD
                     KGDMRKEWGIKPEYVNVKGNKVIARTYYNKYINEEYLEQELPASNTNILTWQTQLIRLA
                     EMYLIAAEAENEINGPAGAYQYINAIRKRARVDQNDPTNVPDLSGLSQDQFREAVLLER
                     QHELYEEGFAWYDLKRTQTFDKVQKARGSRLNVPIGAYNNTWLIPDTEILNNNIPQNPD
                     YR"
     CDS             749..2212
                     /locus_tag="ctg1_2"
                     /transl_table=11
                     /translation="MKKQYIYFLSLFVMCLAACSNPVDPTALNLDSANINRLIPFRGEL
                     NNGVKQLYPEEPYKAFWAENWKTPEQSISWKVNTDGEDYMAEMIVSVNRMGDGEETELV
                     LSNGTDSVICRINTTGWQRCRFPRPLHFNKGTSVLSLKIGKPGKQDDFNVYLYSLEVTR
                     PETYEQLRAEATSLRSNTSWMADLPYGFFFHWNSKSMPQSGEPLAYEDAVNNFDVDRFA
                     RTVYECGGKLIFFTTSWAEYYFPAPIQAIDSILPGRTTKRDLVADLSDALGKYGIRLIL
                     YYHVGHGDKEWWDKQHYTRDNAGDLFTNVEKIVGEISQRYGNRLAGLWMDDGIGYYPNG
                     ASFEKIAKAAKSGNKELAICFNSWILPKLTDFQDYYAGELGLSLASAGVNDPSLPLDGD
                     GLFHGGPQDGLQATFSGTLEPGDWTHIYKDSIIGDPVLSIDELTQVVKESNKRKNLPMI
                     NVRIYQDGTISPKSYALLKELNNRISKGE"
     CDS             2583..4415
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ILVD_EDD"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_3"
                     /sec_met_domain="ILVD_EDD (E-value: 8.8e-217, bitscore:
                     709.9, seeds: 918, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MMKNPLRSSYSTEGRRMAGARALWRANGMKEEQFGKPIIAIVNSF
                     TQFVPGHVHLHEIGQQVKAEIEKLGCFAAEFNTIAIDDGIAMGHDGMLYSLPSRDIIAD
                     SVEYMVNAHKADAMVCISNCDKITPGMLMASMRLNIPTIFVSGGPMEAGNLDGRALDLI
                     DAMIEAADDSISDEQVEKVERSACPTCGCCSGMFTANSMNCLNEAIGLALPGNGTVVAT
                     HANRTRLFKKAAKMIVDNAFKYYRDGDDSVLPRSIATRQAFLNAMSLDIAMGGSTNTVL
                     HLLAVAHEAEVDFTMKDIDMLSRKTPVICKVAPSCSYHVEDVNRAGGIIGIMNELVKAG
                     LVDGSVKRADGLTLNEAIDQYCITSVNVTEEAINIYKSAPAHRFNLVLGSQESYYKELD
                     TDRATGCIRDVEHAYVKDGGLAVLYGNIAQDGCVVKTAGVDESIFRFAGPAKVFDSQDA
                     ACEGILKDQVVPGDVVVITYEGPKGGPGMQEMLYPTSYIKSRHLGKECALITDGRFSGG
                     TSGLSIGHISPEAASGGAIGLVRDGDIIEINIPERSINVRLSDELAERRKAEEARGKKA
                     FTPPTRQREVSKALRAYGKMVSSADKGGVRIVED"
     CDS             4449..6149
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_4"
                     /sec_met_domain="TPP_enzyme_C (E-value: 3e-51, bitscore:
                     162.5, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEKQKITGSEALLKALIAEGVDTIFGYPGGQAIPIYDSLYDYRDQ
                     LKHILVRHEQGATHAAQGYARVSGKVGVTVVTSGPGATNTITGIADALMDSTPMVVIAG
                     QVPSPLLGTDAFQEVDVIGITQPITKWAYQIRRPEEIAWAVSRAFYIASTGRPGPVVLD
                     LAKDAQVGLVDYEYQKVDYVRSYQPEPDIREERIEAAASLINNAKKPFCLVGQGVILGG
                     AEEELKEFLLKNDIPAGSTVLGLSALPSDFPLNKGMLGMHGNVGPNRKTNECDVLIAIG
                     MRFDDRVTGDLKTYAKQAKIIHLDIDNSEIGKNVPVDVKVLGNAKHTIPMITALLEERK
                     RPEWNAEFEPDEKEEYNKVIEKELYPTEGQLKMGEVVRKVSEATDNDAILVTDVGQNQM
                     MGVRYFKYKQTRSVVTSGGLGTMGFGLPAAIGAKLGAPDRTVCFFTGDGGIQMTIQELG
                     TIMQENLNVKIIVLNNNFLGMVRQWQELFFNERYSNTIMKNPDFVAIAKAFGIASRAVD
                     KREDLDEAIAEMLNHDGAYMLVANVETCGMVYPMVPAGGSVTNMILGDK"
     CDS             6162..6716
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ALS_ss_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_5"
                     /sec_met_domain="ALS_ss_C (E-value: 1e-18, bitscore: 56.7,
                     seeds: 685, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNTKQLYTVIIFSENTVGLLNQITVIFTRRQLNIETLSVSPSAIK
                     GIHKFTITTFADEDTIDKVVKQIDKRVDILKAYYNTDEDLVYQEIALYKLSTELFIKMG
                     TVEDLIRKYNARILEMNEDCVVLEKSGHYDETQALFKELSETIGVLQFIRSGRVAITKS
                     KVERLSDMLSAMEKKLQEKHV"
     CDS             6753..7484
                     /locus_tag="ctg1_6"
                     /transl_table=11
                     /translation="MEKNKVGEFHFVTESYLMDFRGRITIPMIGTYLLHAASCHAADRG
                     FGYNDMTERHTAWVLSRLAIEMTSYPAMSESVTLYTWVDEVGKLFPSRCFELVNGEGKT
                     FGFARSIWAAIDMETRRPTLLDVEGLSAYITDRPCPIEKPGKIAPVENNTSGEPYRVKY
                     SDLDVNGHLNSIKYMEHLLDLFDISLFREKEISRFEIAYQSEGKYGMELTLHNQEVSPG
                     KYNMAICNDGKAISRAAVTWI"
     CDS             7526..8572
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: IlvC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) IlvN"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_7"
                     /sec_met_domain="IlvN (E-value: 1.1e-48, bitscore: 154.2,
                     seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="IlvC (E-value: 2.5e-44, bitscore: 140.3,
                     seeds: 295, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAVMNFGGVDENVVTREEFPLEKAREVLKDETIAVIGYGVQGPGQ
                     SLNLRDNGFNVIVGQRKGGKTWEKAVADGWVPGETLFDIEEACEKATIIQYLLSDAAQI
                     EVWPRIKKYLTPGKALYFSHGFGITYKERTNIIPPADVDVILVAPKGSGTSLRRMFLQG
                     RGLNSSYAIFQDATGKAWDRVIALGIGVGSGYLFETTFKKEVYSDLTGERGTLMGAIQG
                     LLLAQYETLRENGHEPSEAFNETVEELTQSLMPLFAENGMDWMYANCSTTAQRGALDWM
                     GPFHDATKPVFQKLYSEVACGNEAQRSIDTNSKPDYREGLEKELAALRESEMWRAGAVV
                     RKLRPENN"
     CDS             9074..12352
                     /locus_tag="ctg1_8"
                     /transl_table=11
                     /translation="MISVLLGAAGAIAANPTGPETMVVQQGNKVTGLVEDQMGPVAGAS
                     VVVKGTTIGMITDIDGKFTLDNVRRGAVIVISFVGLATQEITWNGQSILNVKLSDATQD
                     LDEVVVVAYGTAKKSTFTGSASVVKAEKLEKIMGSGFAEALQGMSAGVNVVNVQGNPGA
                     DARVEIRGIASMSGKADPLYIVDGMPYDGKLNQINPTDIESMTVLKDAAATSLYGSRAA
                     NGVVMITTKRGKSEKPRINFRGGWGTSDNAVKNPKKADPYQQLENTWYALYYDALLYDG
                     MNMQQAGDYASSQALTKQVKATKDSNGNLIYVTPFRHINENYVLHDGNGNPYMNPNLEY
                     VWDEDDWDVYKAIFSRKLRQDYSVDISGQANGGKTAYFFSGGYLDDQGYGNRQYYKRYS
                     FRTNLSTELFDWWKVAGSLSYSRHRQNLSGGASRAANFTTTLSSPWLRNEDNTGWVVSE
                     KTGERMYSYGKYTNNFFGAHILNNSGDYWDNPNDDSFDNNMGHILSAQVNTEFTLPFNL
                     KFRSALNIDDYWYRTMQYTSAVHGSGQTAPYGISILADGGYASRYNFNKRSTTWNNVLS
                     GEWMIGDHTISGLVGHEWYTWDSHYEQGWGEGIMELGKYELSNTTKNFGVSGGRDKYSL
                     LSFFGKVDYNFLNKYYLSASLREDGSSRFSSDHRWGTFWSTGGSWRISKEGFMEDLKWI
                     DNLSLRGSYGTTGNDKLIVRESNGKAGDEVLYGYQGTYESDDLYLKSGLKPSTYPTPDL
                     KWESNQQWNIGLDFSVFNRLSGTVEYYSRTSHDLLYYKELPLSAQVGSASGYNMNIGDL
                     RNSGIEITLNANILTTKDFRWDIDANMSTLKNEVTYLPTGPYTYSGTACTYKMEEGKSL
                     YEFIAPQYDGVNPETGVPGWLIRDGNGGWKRTEKQEEVTTDDFVYCGSAIPKVFGAITN
                     NFQFKGIDLSFMFYYSYGSKISDYTYKERIMNRPGVGVIQELVEDRWRQPGDTDVLIPR
                     WSYNQYGATVKYADNFVFDNHYWRLRNLTLGYTLPKSLTRKALVENLRVYVTGNNLLTF
                     GPAKKRYTDPETGIMGNSYNGNAETDNGIQGSRRLYMVGIQITL"
     CDS             12371..12874
                     /locus_tag="ctg1_9"
                     /transl_table=11
                     /translation="MKRFINISFLSLVFAGMALTGCNDDLTTSSYVKVNDEDVLGNVSQ
                     LEKVLTSAYKQLYFNTDKGDRVYAGLPGFQMYVDASGADVISHTNMGGDQVTAYQYSNS
                     KTQADGNASKIWSMCYNVINRANIILTNVDAAAGDETQKKHIKGQALAMRGIQYFHLIQ
                     NYQQT"
ORIGIN
        1 ttatacggct gaaactatct gggctcagtt gttctccgct cccgatagtt atagcggtat
       61 gcataatgaa tcttcaccga ttggcagcca gacagccttg tatcttccga cagatgcttt
      121 tatcgccagc ttcgataaag gtgacatgcg taaagaatgg ggaattaaac ctgagtatgt
      181 aaatgtgaaa ggaaataaag tcatcgcgcg tacatattat aataagtata tcaatgaaga
      241 gtatctggaa caggagttgc cagcatctaa taccaatatt ttgacctggc agactcaatt
      301 gattcgtttg gctgaaatgt atctgattgc cgccgaagct gaaaatgaga taaacggacc
      361 ggccggtgct tatcaatata tcaatgctat ccgtaaacgt gcccgtgtcg accagaacga
      421 cccgacaaac gtgcctgact tgagcggact ttctcaggac cagttccgtg aagccgttct
      481 gctggaacgt cagcatgaat tgtatgaaga gggttttgcc tggtacgatt tgaaacgtac
      541 ccagacattc gataaggtac agaaagcgcg tggcagcaga ttgaatgtcc ctatcggtgc
      601 ttacaacaat acttggttga ttcctgatac cgaaattctg aataacaaca tacctcagaa
      661 tccggattac agataattaa tgtagaatac atgaagggcc ggtctgagtt attattggat
      721 tggcccttcc tatatccgta aaatacgaat gaaaaagcaa tatatttatt ttttgtcttt
      781 gtttgttatg tgtctggccg cttgcagtaa tccggttgat ccgacggcat taaacctgga
      841 ttcggcgaac ataaaccggt tgattccttt tcgtggagaa ctgaataatg gtgtgaaaca
      901 actttatccg gaagaacctt ataaagcatt ctgggcggag aactggaaaa ctcccgagca
      961 gtcaatatcc tggaaagtca atacggacgg tgaagactac atggctgaaa tgatcgtttc
     1021 tgtcaaccgg atgggagatg gggaagaaac ggagttggta ttatccaatg gaacggacag
     1081 tgttatttgc cggataaata caaccggatg gcagcgttgc cggttccccc gtcctttaca
     1141 ttttaataag gggacttccg ttttatcttt aaagattggc aaacccggta agcaggatga
     1201 ttttaatgtg tatctgtact cgttggaagt cacccggccg gagacttatg agcagctgcg
     1261 ggcggaagct acatcacttc gcagtaatac atcctggatg gcggatttgc cttatggctt
     1321 tttcttccac tggaattcaa agagtatgcc tcagtcagga gagccgttag cctatgagga
     1381 tgcggtcaat aactttgatg tggaccgctt tgcacgaact gtttacgaat gtggcgggaa
     1441 gttgatattt tttacaacgt cgtgggcgga atattatttc ccggctccga tacaggcaat
     1501 cgattctatt ttgccggggc gtaccacaaa gagagattta gtggctgatt tatctgatgc
     1561 gttgggtaaa tacggcattc gtctgattct gtattaccat gtcggtcatg gagataaaga
     1621 atggtgggac aagcagcatt atacacggga taatgcagga gatttgttta caaatgtgga
     1681 aaagatagtg ggagagatta gccagcggta tggaaatcgt ctggccggtt tgtggatgga
     1741 tgacggtatc ggttattatc ctaacggtgc ctcgtttgaa aagattgcta aagccgccaa
     1801 aagtggaaat aaggagttgg caatttgttt caattcctgg atattgccga agctgacgga
     1861 ctttcaggat tattatgctg gcgaactggg tttgtctttg gccagtgccg gtgttaacga
     1921 tccttctctt ccgttggatg gggacggatt gtttcacggt ggccctcagg atggcttaca
     1981 ggcaactttc tccggaacat tggagccggg tgactggacg cacatttata aagattccat
     2041 tatcggtgat cctgttcttt ccattgacga attgacgcag gtagtgaaag aatctaacaa
     2101 acgaaaaaat cttccgatga ttaatgtccg gatttatcag gatggaacga tttctccgaa
     2161 atcgtatgct ttgttgaaag aactgaacaa tcgtatcagt aaaggagaat gaccggaaat
     2221 tatcgaatat gaagcgaatg gaggctcaga aataagaatt caattgattg agggctggtt
     2281 atctgttaaa atgcaagatg aaccgccctc ttttcttgat aaatgaaaga aaaagtaaga
     2341 tttttctttt aaatcctttg ctcgtacaaa ttattattct acatttgcag cgtcaaacaa
     2401 aataaagacg ataagaaaag atgatgaaca atgtattaca tattattctc gtggtggtcc
     2461 ttctagtcat tagtaggtaa ggagaaaggt gtgtaagaag ttgtgaagtc gtaaaagata
     2521 tttcttaagc ctttctccat atagagaagg gcttttttat tgactaaaag ataaaaacag
     2581 atatgatgaa gaatccgtta agaagctcct atagcacaga aggcagacgt atggccggtg
     2641 cccgtgcatt atggcgtgcc aacggcatga aagaagaaca gttcggtaaa ccgatcattg
     2701 ccattgtgaa ttcatttacc cagtttgtac cgggccatgt gcatctacac gagatcggac
     2761 agcaggtaaa agcggaaatc gaaaagctcg gttgctttgc cgcagaattt aatacgatcg
     2821 ctattgatga cggtattgct atgggacacg acggaatgct ttattctctg ccttcccgcg
     2881 acatcattgc tgacagtgtg gaatatatgg tgaatgcgca taaggctgat gcaatggttt
     2941 gtatcagtaa ctgcgacaag attactccgg gtatgctgat ggccagtatg cgtctgaata
     3001 ttccgacaat ctttgtatcc ggcggtccga tggaagccgg taatctggac ggacgtgcac
     3061 tcgatttgat cgacgccatg attgaagcgg ctgacgattc tatcagcgat gaacaagtag
     3121 aaaaggtgga acgttccgct tgcccgacct gcggttgctg ttccggtatg ttcacggcta
     3181 actctatgaa ctgtctgaac gaagcgattg gattggctct tcccggcaac ggaacagttg
     3241 ttgcaacaca tgccaaccgt actcgcttgt tcaaaaaagc ggcgaagatg attgttgata
     3301 atgcctttaa atattatcgt gacggcgatg attccgtatt gcctcgcagt attgccaccc
     3361 gtcaggcctt tctgaatgct atgtcgctgg atattgccat ggggggatcg acgaatacag
     3421 tccttcacct gttggccgtg gctcatgaag cggaagtcga ttttacaatg aaagacatcg
     3481 atatgctttc acgcaaaaca ccggttatct gtaaagtggc tccgagttgt tcttatcatg
     3541 tggaagatgt gaaccgtgcc ggaggtatca tcggtattat gaatgagctg gtaaaagccg
     3601 gtctggtgga cggttccgtg aaacgtgcgg atggtctgac tttgaatgag gctatcgacc
     3661 aatactgcat tacctctgta aatgtaacgg aagaagcaat caatatttat aaaagtgctc
     3721 cggcccaccg tttcaacctg gtgctcggat cgcaggaaag ttattataaa gaactggata
     3781 ccgaccgtgc aaccggatgt atccgcgatg tggaacatgc ttatgtgaaa gacggcggtc
     3841 tggctgttct gtatggaaat attgcacagg acggttgtgt ggttaaaaca gccggggtag
     3901 atgaaagtat cttccgtttt gccggccctg ccaaagtatt cgattcgcag gatgccgctt
     3961 gcgaaggtat cctgaaagat caagtcgtcc ccggcgatgt cgtcgttatc acctatgaag
     4021 gtcctaaggg tggtccgggt atgcaggaaa tgttgtatcc tacctcttat ataaagagcc
     4081 gtcacttagg taaggagtgc gccttgatca cggatggtcg tttcagtggc ggtacgtccg
     4141 gtctttctat cgggcatatc tctcctgagg ccgcttccgg tggcgctatc ggactggtga
     4201 gagacgggga tatcatcgag atcaatatcc cggaacgttc catcaacgtg cggctgagcg
     4261 acgagttggc cgagcgccgt aaagcggaag aggcgcgtgg aaagaaagcc tttacgccgc
     4321 cgacgcgtca gcgtgaggtc tcgaaagcgt tgagagcgta cgggaagatg gttagctccg
     4381 ccgataaggg aggtgtaagg attgttgaag attaaagcca ataatataca ttaaacacgt
     4441 tatttcttat ggagaaacaa aagataaccg gttcggaagc tttgctgaaa gcgttgattg
     4501 ctgaaggagt agatactatc ttcggttatc cgggtgggca ggcgatacca atttacgata
     4561 gtttatacga ttacagagat cagttaaaac atattctggt gcgccacgaa caaggtgcaa
     4621 cacatgctgc acagggatat gcccgtgttt ccggaaaagt gggagtaacg gtggttactt
     4681 cgggtcccgg ggcaaccaat accatcactg gtattgccga tgcgctgatg gacagtacac
     4741 cgatggtggt gattgccggc caggttccgt ctccgctgct tggaacagat gctttccagg
     4801 aagttgatgt aattggtatc acacaaccga ttaccaaatg ggcttaccag atacgccgcc
     4861 cggaagaaat tgcttgggcc gtttcccgtg ctttctatat cgcatcgacc ggtcgcccgg
     4921 gacctgtggt actggatttg gcgaaagatg cacaggtggg tttggtagat tatgagtatc
     4981 agaaagtgga ttatgttcgt agttaccagc ctgaaccgga tatcagggag gaacgtatcg
     5041 aggcggctgc ttcattgata aataatgcca aaaagccatt ctgtctggta gggcaggggg
     5101 ttatcctagg aggagctgaa gaagaactga aagaattctt gttgaaaaac gatataccag
     5161 ccggttctac cgtattgggc ttgtctgcat taccttcgga cttcccatta aataaaggta
     5221 tgttggggat gcatggaaat gtcggaccga accgcaagac taacgaatgt gacgtgctga
     5281 ttgctatcgg tatgcgtttc gatgatcgcg taaccggcga cttgaagact tatgccaagc
     5341 aggcaaagat tatccacctg gatatcgaca attcggagat cggaaagaat gtgccggtcg
     5401 acgtgaaagt gctgggaaat gccaagcata cgattccgat gattacggct ttactggaag
     5461 aacggaagcg tccggaatgg aatgctgaat tcgaaccgga tgaaaaagag gaatataata
     5521 aggtaataga aaaagaactc tatcctaccg aaggccaact gaaaatgggc gaagtagtcc
     5581 gtaaggtttc cgaagcaacc gataatgatg cgattctggt tacggatgta ggtcagaacc
     5641 agatgatggg tgttcgctat ttcaaatata aacaaacacg cagcgtagtt acttcaggag
     5701 gtttgggaac gatgggcttt ggccttcccg ccgccattgg agcgaagctg ggagcgcctg
     5761 accgtacggt ctgtttcttt accggcgacg gtggtatcca gatgactatc caggagttgg
     5821 gaactatcat gcaggaaaat ctgaatgtaa agatcatcgt tcttaacaac aatttcctgg
     5881 gaatggtacg ccagtggcag gagctgttct tcaacgaacg gtattcgaat accatcatga
     5941 agaatccgga ttttgtagcg atagccaagg cttttggtat tgcttcccgt gcggtagata
     6001 aacgggaaga cttggatgag gcgattgctg aaatgttgaa tcacgatggt gcctatatgt
     6061 tggttgccaa tgtggaaact tgtggtatgg tatatccgat ggttccggcc ggaggaagcg
     6121 tgacaaacat gattttgggt gataagtaag gaggagaaac tatgaataca aaacaattat
     6181 ataccgttat tatcttttcg gaaaacactg ttggtcttct gaatcagata actgttatct
     6241 ttacgcgccg gcaactgaac attgagacgc tttctgtttc tccctctgct ataaagggaa
     6301 tacataagtt tacaattact acctttgccg acgaggatac gatcgacaag gtcgtaaaac
     6361 agatcgacaa gcgtgtggat atcctgaaag cttattataa tacggatgaa gacctggttt
     6421 accaggaaat cgctctttat aaactgagta ccgaactctt tatcaagatg gggacggttg
     6481 aggatctgat ccgtaagtac aatgcccgta tccttgaaat gaatgaggat tgtgtggtgt
     6541 tggaaaagag tggtcattat gatgagacac aggctttgtt taaagaattg agtgagacga
     6601 tcggtgtcct gcaatttatc cgttccggac gcgttgctat aacgaagagt aaggtagaac
     6661 gtctgagcga catgttatct gcaatggaaa agaagttgca ggaaaaacat gtctgagaat
     6721 aataaggaaa cattttgtaa ataaagtaaa ttatggagaa gaacaaagta ggagaatttc
     6781 atttcgtaac agagtcttat ctgatggact tccggggacg tattacaatc cctatgatcg
     6841 gaacttattt gttgcatgct gcttcttgcc atgccgccga ccgtggattc ggatataacg
     6901 atatgaccga aaggcatacc gcctgggttc tttcccgtct ggctatcgag atgacttctt
     6961 atcctgccat gtctgaatcc gtaactttat atacctgggt ggatgaggtc ggtaagttgt
     7021 ttcccagccg ttgctttgaa ctggtgaacg gcgaaggcaa gacctttggc tttgcccgct
     7081 ctatctgggc ggctatcgat atggaaaccc gccgcccgac cttgctcgat gtggagggcc
     7141 tgagtgctta tatcaccgac cgtccctgtc cgattgaaaa accgggtaaa attgctccgg
     7201 tggaaaacaa cacttccggc gaaccttacc gtgtgaagta cagtgacctg gacgtaaacg
     7261 gccacctgaa cagtatcaaa tacatggaac acctgctcga cttgttcgat atcagtctgt
     7321 tccgagaaaa agagataagc cgtttcgaaa tagcttatca gtccgaagga aagtatggga
     7381 tggagctgac tctccataac caggaagtat cccccggtaa atataatatg gcaatctgta
     7441 acgacggcaa agccatcagc cgcgctgccg ttacctggat ctgaaaaaca aattatttta
     7501 tatacatttt aatagtaaaa agaaaatggc agtaatgaat tttggcggcg ttgacgaaaa
     7561 cgtagtaacc cgcgaagaat ttccgttgga aaaggcaaga gaagtattga aagacgaaac
     7621 aatcgctgta ataggttacg gcgtacaagg tcctggccag agcctgaacc tgcgcgacaa
     7681 cggttttaac gtaattgtag gacaacgtaa aggtggtaag acctgggaaa aggccgttgc
     7741 tgacggttgg gtaccgggcg aaacactgtt cgatatcgaa gaagcatgcg aaaaagcgac
     7801 tatcatccag tatctgcttt cagatgctgc tcagattgaa gtttggccgc gcatcaaaaa
     7861 atacctgact ccgggtaagg ctttgtattt ctctcacgga ttcggcatca cttacaaaga
     7921 acgtacaaac atcatccctc ctgctgatgt agacgtaatc ctggttgctc cgaaaggttc
     7981 aggtacttca ctgcgccgta tgttcttgca gggtcgtggt ctgaactcaa gctacgcaat
     8041 cttccaggat gcaacaggca aagcatggga tcgcgtgatt gcactgggta tcggtgttgg
     8101 ttctggttac ttgtttgaaa caacattcaa gaaagaagtt tattctgacc tgaccggcga
     8161 acgtggtact ttgatgggag ctatccaggg attactgttg gctcagtacg aaactttgcg
     8221 tgaaaacggt cacgaacctt ctgaagcatt caatgaaaca gtagaagaac tgactcagtc
     8281 attgatgccg ttgttcgcag aaaacggtat ggactggatg tatgcaaact gttcaacaac
     8341 tgcacagcgt ggtgctttgg actggatggg cccgttccac gatgctacaa aaccggtgtt
     8401 ccagaagttg tatagcgaag ttgcctgcgg taacgaagca cagcgttcta tcgacacaaa
     8461 cagcaagcct gactatcgtg aaggtctgga aaaagaactg gctgctcttc gcgaaagtga
     8521 aatgtggcgt gcaggtgctg ttgttcgtaa acttcgtcct gaaaacaact aataaatggt
     8581 gatacattaa tagttaaaca ttttgtgata taaaaacggc aatccggctt ttcgggttgc
     8641 cgttttttta tggtttatgt aatgtgttaa tggttaaaaa atgtttttga ttgcaactgt
     8701 tattgatttt tcatcccaat atgtatgtca ttgtttgaat gtggatttta gataaaaaaa
     8761 tcaattaaat ggtggttaaa atatatttat tagagcaata aatatacata attatgcttg
     8821 tattaaataa tgataagtta tatttgctga tggagatact gtagtttgta gagtggaaat
     8881 atagaaggat gttgtgtgta atgatcagta tatctttgtt ttagttaact ttattttatt
     8941 gaaatgtatg ccagtcactt ttatcttaga aaagtgtaac ctctaatgaa atgaacgcta
     9001 ttgtgattaa ttttatttaa ttaaagactt gaatttagct atgtggacca actcaaaact
     9061 aattagatca ctaatgattt ctgtattatt aggtgcggca ggtgcgattg ctgccaatcc
     9121 tacaggtccg gaaacgatgg tagtacaaca gggtaataag gtaaccggcc tggtagagga
     9181 ccaaatggga cctgtcgccg gagcttctgt tgtagtgaaa ggaaccacta tcggtatgat
     9241 aaccgatatc gatggaaagt ttacgctgga taatgttcgg cggggagcgg ttattgttat
     9301 ttcctttgtc ggcctggcca ctcaggagat cacttggaac ggacaatcta ttttaaatgt
     9361 aaaattaagt gatgcgacac aggacctgga tgaagtcgtt gtcgtagcct atggaacggc
     9421 taagaaatca accttcaccg gatcggcctc cgttgtaaaa gctgaaaaac tcgaaaagat
     9481 catgggctcc ggctttgcgg aagcattgca ggggatgagt gccggtgtga atgttgtgaa
     9541 tgtacagggt aaccccggag ctgatgcccg tgtggagatc cgtggtattg cttccatgtc
     9601 cggaaaggcc gatccgttat atattgtgga cgggatgcct tacgatggaa aactgaacca
     9661 gatcaatcct acggacatag aatcgatgac ggtgctgaag gatgcggcgg ccacttcgct
     9721 ttacggttcg cgtgcagcaa acggcgtcgt aatgattaca accaagcggg gtaaatcaga
     9781 aaaaccgcgt attaacttcc gcggaggttg gggtacttcg gataatgctg tcaagaatcc
     9841 gaaaaaagcc gatccgtacc agcagctgga aaatacctgg tatgccttgt attatgatgc
     9901 ccttctttat gacggcatga atatgcaaca ggcgggcgat tatgcttcgt cacaggcatt
     9961 gaccaaacag gtaaaggcta caaaagattc gaatggtaat ctgatttatg tcactccgtt
    10021 cagacatatc aatgaaaatt acgtattgca tgacggcaat gggaatcctt acatgaatcc
    10081 taatctggaa tatgtctggg atgaagatga ttgggatgtc tacaaagcta tcttctcccg
    10141 taaactgcgc caggattata gtgtggatat aagtggtcag gccaatggtg gaaaaacagc
    10201 ctatttcttc tccggcggtt atctggacga ccagggatat ggtaaccggc agtattataa
    10261 acgttattct ttccgtacca acctgagtac agagttgttc gattggtgga aagtggccgg
    10321 tagcctttct tattcgcgtc atcgccagaa cctttccggt ggtgccagcc gtgcggctaa
    10381 ctttacgacg actttgtctt caccctggtt acgtaatgaa gataataccg gttgggtcgt
    10441 ttctgaaaaa acaggggaac ggatgtacag ttacggtaaa tataccaata acttctttgg
    10501 tgcccatatc ctgaataact cgggtgatta ttgggataat ccgaacgatg acagtttcga
    10561 taacaatatg gggcatatcc tgtctgccca ggtaaataca gagtttactc ttcctttcaa
    10621 cctgaaattc cgttcggctt tgaatattga cgattactgg tatcgtacca tgcaatatac
    10681 ttccgccgta catggcagcg gacagactgc accttatggt atttctatac tggcagacgg
    10741 tggttatgcc agccgttata atttcaataa acgttccacc acctggaata atgtattgtc
    10801 tggtgaatgg atgattggtg accatacgat ttcaggtctg gtcggacatg agtggtatac
    10861 ctgggactcc cactacgaac aaggttgggg tgaaggtatc atggaactgg gtaaatatga
    10921 attatcgaat accaccaaga acttcggtgt ttccggcgga cgtgataaat actctctgct
    10981 ttcgttcttc ggtaaagtcg attataactt cttgaataag tattacttgt ccgcttcgct
    11041 tcgtgaggat ggttcttccc gtttcagttc cgatcatcgc tggggtacat tctggtcgac
    11101 aggcggttcg tggcgaatat cgaaagaagg ttttatggaa gacctgaaat ggattgataa
    11161 cctttcgttg cgtggtagtt acggtacgac tggtaatgat aagctgattg tgcgtgaatc
    11221 gaatggtaag gcaggggatg aagtccttta cggataccag ggtacttatg aaagtgatga
    11281 cctgtatctg aaatccggtt taaaaccatc tacctatccg acaccggact tgaagtggga
    11341 aagtaatcag caatggaata tcggtttgga tttctccgta ttcaaccgac ttagcggtac
    11401 agtggaatat tattcccgta cttcccatga tttgttgtat tataaggaac tgcctctgtc
    11461 tgcccaggtt ggtagtgcat ctgggtataa tatgaatatc ggtgacctgc gtaatagcgg
    11521 gattgaaatc acattgaatg cgaatatcct tacaacgaaa gatttcagat gggatatcga
    11581 tgccaacatg agtacgctga aaaatgaggt gacttatttg cctacaggtc cttacactta
    11641 ttctggtacc gcctgtacct acaagatgga agaaggcaag tccctgtatg aatttatcgc
    11701 tccccagtac gatggtgtta atccggaaac cggagtaccc ggctggttga tccgcgatgg
    11761 taacggcggt tggaaacgta cggaaaagca ggaagaagta acgacagacg attttgtgta
    11821 ctgtggctcc gcgattccca aagtgttcgg tgctatcacc aataacttcc agttcaaagg
    11881 gatcgacctg tcgttcatgt tctattattc ttatggttcc aaaatatcgg actatacata
    11941 taaagaacgt atcatgaacc gtccgggtgt cggtgtgata caggagttgg ttgaggacag
    12001 atggcgtcag ccgggcgata cggatgtgct tatcccacgt tggtcgtaca accagtatgg
    12061 cgcgacggta aaatatgcag ataacttcgt gttcgacaac cactactggc gtctgagaaa
    12121 cctgacatta ggctatacgc tgcctaagag ccttacccgc aaggccctgg tagaaaacct
    12181 gcgtgtttat gtaaccggta ataacctgtt gactttcggt cctgccaaaa aacgctacac
    12241 agaccccgaa acaggtataa tgggtaacag ttataacggt aatgctgaaa ccgataacgg
    12301 tattcagggt tcgagaagac tgtatatggt cggtattcaa atcacattgt aaacgtaaaa
    12361 aatgatattt atgaaacgat ttataaatat atccttcctg tccctggttt ttgctggtat
    12421 ggccctgacc ggatgtaacg acgacctgac aaccagctcc tatgtgaaag taaacgatga
    12481 agatgtactg gggaatgtct cccagttgga aaaagtattg acttcagcct ataagcagct
    12541 gtattttaat accgataaag gcgaccgtgt gtatgctggt cttcccggat tccagatgta
    12601 tgtcgatgcg agtggtgccg acgtgatcag ccataccaat atgggaggtg atcaggtaac
    12661 agcataccag tattccaact caaaaacaca ggctgacgga aatgcctcaa aaatctggtc
    12721 gatgtgctat aatgtgatca accgtgccaa tatcatcctg accaatgtgg atgccgccgc
    12781 cggtgatgaa acacagaaaa aacatatcaa aggccaggcg ttggcgatgc gtggaatcca
    12841 gtatttccat ctgatccaga attaccaaca gacgt
//
