LOCUS       c00086_gnlPro..         5618 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|BKDECHHB_86.
ACCESSION   c00086_gnlPro..
VERSION     c00086_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-07 20:19:34
            Original ID  :: gnl|Prokka|BKDECHHB_86
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 5618
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..5618
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[890:5129]"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      891..5129
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
     cand_cluster    1..5618
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /kind="single"
                     /product="TPP_AA_metabolism"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..5618
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="TPP_AA_metabolism"
                     /region_number="1"
                     /rules="(TPP_enzyme_C and not (PFL-like or PFL_6_pcresol or
                     PFL_9_tma or Gly_radical or Gly_430_pcre or Gly_8-9_TMA or
                     PFL_acetate1 or PFL_acetate2 or Gly_radical_scatole or
                     PFL_proline or PFL_toluene) and minimum(2, [ALS_ss_C,
                     AlaDh_PNT_C, Arginase, BKACE, BcrAD_BadFG, Beta_elim_lyase,
                     CPSase_L_D2, Cys_Met_Meta_PP, ELFV_dehydrog, GRDB,
                     Glu_syn_central, Glu_synthase, Gly_reductase, HAAA1, HG2B1,
                     HG2B2, HGD-D, HleuD1, HleuD2, HleuS1, HleuS2,
                     Homoserine_dh, ILVD_EDD, IlvC, Lactoyl-CoA1, Lactoyl-CoA2,
                     Lyase_aromatic, MAAL_C, OKR_DC_1_5_lysine,
                     OKR_DC_1_5_ornithine, OKR_DC_1_7_arginine, OKR_DC_1_C,
                     OTCace, PALP, Proline_reductase, Sacchrp_dh_C, TPL,
                     Thr_dehydrat_C, TnaA, Urocanase]) and not (POR or POR_N or
                     PFOR_II))"
                     /tool="gutsmash"
     CDS             complement(2..91)
                     /locus_tag="ctg86_1"
                     /transl_table=11
                     /translation="MAQLNFGGVIENVMTREEFPLEKAREILKD"
     CDS             complement(142..894)
                     /locus_tag="ctg86_2"
                     /transl_table=11
                     /translation="MMSENNKIGTYKFVAEPFHVDFTGRLTMGVLGNHLLNCAGFHASD
                     RGFGIATLNEDNYTWVLSRLAVELDEMPYQYEDFSIQTWVENVYRLFTDRNFAIIDKEG
                     KKIGYARSVWAMISMNTRKPADLLALHSGSIVDYVCDEPCPIEKPSRIKVASKEPVAAL
                     VAKYSDIDINGHVNSIRYIEHILDLFPIEMYKEKRIRRFEMAYIAESYYGDELTLFMDD
                     AGEGVYDVEVKKNGSEVVCRSKVIFTEK"
     CDS             complement(891..1451)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ALS_ss_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg86_3"
                     /sec_met_domain="ALS_ss_C (E-value: 3e-20, bitscore: 60.8,
                     seeds: 685, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDKKLYTIIVHSENFAGLLNQVTAVFTRRQINIESLNVSASSIKG
                     VHKYTITAWTDKDTIEKVTKQITKKIDVLQAHYFTDDEIYQHEIALYKITTPTLEEKPE
                     VSKVIRKYNARIVEVNAVFAIVEKNGMSEEITNLYEELRQLDCVLQFVRSGRVAITTSC
                     FERVNEYLADREAKYRQSKHQES"
     CDS             complement(1484..3235)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg86_4"
                     /sec_met_domain="TPP_enzyme_C (E-value: 4.2e-48, bitscore:
                     151.4, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MADNNKKSNFSSLSQGEGRGEALITGAEALMRSLEHQGVKTIFGY
                     PGGSIMPVFDALYDHRKELNHILVRHEQGATHAVQGFARVSGEVGVCLVTSGPGATNTI
                     TGIADAMIDSTPIVVIAGQVGTNFLGTDAFQEVDLVGITQPITKWSYQIRRAEDVAWAV
                     ARAFYVAKSGRPGPVVLDFAKNAQVEKTEYAPTKVDYVRSYLPVPEMEPEAIRKAAELI
                     NGAERPLVLVGQGVELGEAQQELRAFIEKAGMPAGCTLLGLSALPTNHPLNKGMLGMHG
                     NLGPNINTNKCDVLIAVGMRFDDRVTGKLETYAKQAKIIHFDIDPAEIDKNVKTDVAVL
                     GDCKETLAAVTQLLEPANHQEWIDSFRQYEEVEEEKVIRPELHPAGKALSMGEVVRAVS
                     EATHNEAILVTDVGQNQMMSARYFKYSKERSIVTSGGLGTMGFGLPAAIGATFGRPDRT
                     VCVFMGDGGLQMNLQELGTIMEQKAPVKMILLNNNFLGNVRQWQAMFFNRRYSFTPMMN
                     PDYMKIASAYDIPARRVMTREELAKAIDEMIATDGPFLLEACVEEEGNVMPMTPPGGSV
                     NQMLLEC"
     CDS             complement(3327..5129)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ILVD_EDD"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg86_5"
                     /sec_met_domain="ILVD_EDD (E-value: 1.3e-219, bitscore:
                     718.4, seeds: 918, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKHQLRSSFSTQGRRMAGARALWTANGMKKEQMGKPIIAIVNSFT
                     QFVPGHVHLHEIGQFVKEEIEKLGCFAAEFNTIAIDDGIAMGHDGMLYSLPSRDIIADS
                     VEYMVNAHKADAMVCISNCDKITPGMLMAAMRLNIPTVFVSGGPMEAGEWNGQHLDLID
                     AMIKSADESVGDKEVAQIEQHACPTCGCCSGMFTANSMNCLNEAIGLALPGNGTIVATH
                     ENRKKLFEDAARLIVENAFRYYEEGDESVLPRSIATREAFLNAMTLDIAMGGSTNTVLH
                     LLAVAHEAGADFKMDDIDMLSRKTPCLCKVAPNTQKYHVQDVNRAGGIIAIMDELAKGG
                     LVDTNVRRVDGMTLAEAIDRYSITSSNVCKEAIKKYSSAAAGKFNLVLGSQNASYKELD
                     TDRATGCIRDLEHAYSKDGGLAVLKGNIAQDGCVVKTAGVDESIWKFTGPAKVFDSQDA
                     ACDGILGGKVVSGDVVVITHEGPKGGPGMQEMLYPTSYIKSRHLGKECALITDGRFSGG
                     TSGLSIGHVSPEAAAGGNIGKIKDGDIIEIDIPNRSINVKLTDEELAARLMTPVTRNRE
                     VSKALKAYASMVSSADKGAVRLID"
ORIGIN
        1 catctttcaa aatttcacgt gctttttcca aaggaaattc ttcgcgggtc attacattct
       61 caataacacc gccaaaattc aattgtgcca ttttttgttt taatttttat ttgtggctta
      121 cgccaacgtt gataaattta tttatttctc tgtaaatatc actttagagc gacagaccac
      181 ttcgctgcca ttctttttca cctccacatc gtaaacgccc tcaccggcat catccatgaa
      241 caaagtcaac tcatccccat aatagctttc ggctatatat gccatttcaa aacgacggat
      301 gcgcttctcc ttatacatct ctatcgggaa caaatcaagg atatgctcga tgtaacggat
      361 gctgttcaca tgcccgttaa tgtcaatatc actgtatttg gctaccaaag cagcaaccgg
      421 ttcctttgag gccaccttta tccgcgaagg tttttctatc gggcaaggct catcgcaaac
      481 ataatctaca atgctgccac tatgaagagc cagcaaatct gccggcttac gggtattcat
      541 gctaatcatc gcccaaacgg aacgtgcata cccaatcttc ttaccctcct tatcgatgat
      601 agcgaaatta cggtctgtaa aaaggcgata gacattctcc acccaagtct gaatggagaa
      661 atcttcgtac tgataaggca tttcatccag ttcgacagcc agacgggaca atacccaagt
      721 ataattgtcc tcgtttagag tcgcgatgcc aaaaccgcgg tcgctggcat ggaaacccgc
      781 acaattcaac aaatggttgc ccaatactcc cattgtcagc cgtccggtaa agtcgacatg
      841 aaacggttcg gcaacaaact tgtaggtacc tatcttattg ttctcgctca tcatgattcc
      901 tggtgtttac tttgacgata ttttgcttca cggtccgcca gatattcatt gacacgctca
      961 aagcagctgg tcgtaatggc tacgcgaccc gaacggacga actgaagtac gcaatccaac
     1021 tggcgcaact cctcataaag attggttatt tcctcactca tgccattctt ctcaacaatg
     1081 gcaaatacag cattcacctc cacaatacgg gcattgtact tacggattac tttggacacc
     1141 tccggttttt cttccagcgt aggggtcgtt attttataaa gggcaatctc gtgctgatag
     1201 atttcatcat ccgtgaaata atgggcttgc agcacatcta ttttcttggt aatctgcttg
     1261 gtcacctttt caatggtatc cttgtccgtc caagcggtaa tggtatattt atgtaccccc
     1321 ttgatggagg aggccgatac attcaaactc tcgatgttta tctgccggcg ggtaaacaca
     1381 gccgtcacct gattcagcaa accggcaaag ttttccgaat gaacaatgat tgtatatagt
     1441 tttttatcca tagatagagt aagttcttta atttcgcatg acttcagcat tccaacaaca
     1501 tctgattgac cgaaccgccc ggaggtgtca tcggcattac atttccttct tcctccacac
     1561 aagcttcgag caggaacggt ccgtcagtcg ctatcatctc gtcaatcgct tttgccagct
     1621 cctcgcgggt cattaccctg cgtgcaggaa tatcatatgc cgaagcaatc ttcatataat
     1681 ccggattcat catcggagta aacgaataac gacgattgaa gaacatcgcc tgccattgac
     1741 gaacattgcc caggaagtta ttgttcaaca gaatcatctt caccggagcc ttttgttcca
     1801 tgatggtacc cagttcctgc aggttcatct gcaagccgcc gtctcccatg aatacgcata
     1861 ccgtgcggtc cggacgtcca aaagtggcac cgatagctgc cggaaggccg aagcccatag
     1921 tacccaggcc accggaagta acaatgctac gttccttgct gtatttgaaa taacgggcgg
     1981 acatcatctg attctggccg acatcagtca ccaatatcgc ctcgttatgg gtagcctcac
     2041 tcacagcacg caccacctca cccatgctta gcgcttttcc tgccggatgt aattccggac
     2101 ggattacctt ttcctcttcc acttcctcgt attgccggaa actgtcaatc cattcctgat
     2161 ggttggcggg ttccagcaat tgggtaacgg cagccagtgt ctctttgcaa tctcccagga
     2221 cagcaacatc agtctttaca ttcttatcta tttcggcagg gtcaatatca aagtggataa
     2281 tcttcgcctg cttggcatat gtttccaatt tacccgtcac acggtcatca aagcgcatgc
     2341 ctacggcgat aaggacatca catttattgg tattgatatt gggccccagg ttaccgtgca
     2401 taccaagcat tcctttgttc aacggatggt tcgtaggtaa tgcggaaagt cccaataaag
     2461 tgcatccggc aggcattccg gctttctcaa tgaaagcacg aagctcttgc tgggcttctc
     2521 ccagctccac gccttgtcct accagcacca aaggccgttc cgcaccattt attaattcag
     2581 cagccttccg tatggcctcc ggctccattt cgggaacggg aagatagcta cggacatagt
     2641 ccaccttagt aggcgcatat tctgttttct ccacttgggc gtttttagca aaatccagca
     2701 cgaccggtcc cggacgtccg ctctttgcca catagaaagc acgtgccact gcccaggcca
     2761 catcttctgc acgacgaatc tggtaactcc atttcgtgat aggctgagta atgcctacca
     2821 agtccacttc ctgaaatgca tccgtaccca agaagttcgt ccctacctgg ccggcaatga
     2881 caacgatagg cgtactgtca atcatggcat ctgcaatgcc cgtgatagta ttggtagcac
     2941 ccggtccact ggtaaccaga caaacgccaa cctcgcctga tacacgtgca aagccttgta
     3001 ccgcatgggt tgctccttgt tcatggcgaa ccaagatgtg gttcaattcc ttccggtggt
     3061 cgtataaggc atcgaatacc ggcatgatgc tccctcccgg ataaccgaaa atagtcttta
     3121 ctccctgatg ctccagagag cgcatcaatg cttctgcgcc tgttattaga gcctcacccc
     3181 gaccctctcc ttgggagagg gaggaaaagt tactcttttt attattatca gccatacttt
     3241 atctattcat tatatttaaa agctcaatag tagcttgaaa aatttgtttc attctctcct
     3301 cccctcgctt tcggaaaggg gggcttttaa tcaatcagcc tcacagcccc tttgtcagcg
     3361 gaactcacca tactggcata tgctttcaat gctttggaga cttcacggtt gcgggttacc
     3421 ggagtcataa ggcgtgctgc aagctcttca tccgtcaact tcacattgat agaacggttc
     3481 ggtatatcaa tttcgataat gtccccatcc ttaatcttgc cgatattacc accggcagcc
     3541 gcttcgggag aaacatgtcc gatacttagt ccggaagtac caccactgaa acgcccgtcg
     3601 gtaatcaatg cacactcctt acccagatgg cgggatttga tataagaagt aggataaagc
     3661 atctcttgca tacccggtcc acctttcggc ccttcgtgag tgatgacgac gacgtctcca
     3721 ctgaccacct ttccacccag aataccgtca caagccgcat cttgtgagtc gaagactttc
     3781 gctggccccg taaatttcca gatactctcg tctacaccgg cagtcttgac aacgcaaccg
     3841 tcctgagcta tatttccctt caaaaccgcc agaccgccat ccttgctgta tgcatgttcc
     3901 aaatcacgga tacaaccggt cgcacggtcc gtatcgagtt ccttataaga cgcattttgt
     3961 gagccgagta ccagattgaa ctttccggct gccgcactgg agtatttctt gattgcctct
     4021 ttacatacat tagagctggt aatactatac cggtcgattg cctctgccaa cgtcattcca
     4081 tccacacggc ggacattcgt atcgaccaat ccgcccttgg caagctcatc catgatggca
     4141 atgatgccac cggcacggtt aacgtcttgt acatgatact tttgggtatt gggagccacc
     4201 ttgcataagc agggggtctt gcgggagagc atgtcaatat cgtccatctt aaaatccgct
     4261 ccggcttcgt gagccacagc caacaaatga agtaccgtat tagtggaacc gcccatcgca
     4321 atatccagcg tcatggcatt caaaaatgcc tcgcgggtag caatactgcg cgggagtaca
     4381 ctctcatccc cttcttcata atatctaaag gcattctcta caatcaacct ggctgcatcc
     4441 tcaaatagtt tcttgcgatt ttcgtgagtg gctacaatcg tgccgttacc gggcagtgcc
     4501 aatccaatcg cttcattcaa gcaattcatg gaattagcgg taaacatgcc tgagcagcat
     4561 ccgcaagtgg ggcaggcatg ttgctcaatc tgtgccacct ctttatcgcc cacactttca
     4621 tcagcagatt taatcatggc atcaatcaaa tccaaatgct gtccgttcca ttccccggct
     4681 tccatcggac cgcctgaaac aaacacagtc ggtatattca gcctcatagc cgccatcagc
     4741 atccccggag taatcttgtc acagttactg atgcaaacca tagcatctgc cttatgggca
     4801 tttaccatat actccacact atcggcaatg atatctcttg aaggcaggga ataaagcata
     4861 ccgtcgtgtc ccatagcgat accgtcgtca atggcaatcg tattgaactc cgcagcaaaa
     4921 caccccagtt tttcaatctc ttcctttaca aactggccta tttcgtgcag gtgtacatgc
     4981 ccggggacga attgtgtaaa tgaattgact atagcgataa tgggcttacc catctgttcc
     5041 ttcttcatac cattcgccgt ccacaatgca cgggctcccg ccatgcggcg accttgtgtg
     5101 ctgaacgagc tgcgtaactg atgcttcatt ttcaaatctc cttttaatga aaaagcctct
     5161 cccactatag tgagaaaggc ttaataaatt atcttctaac gtacgaatac atacataacc
     5221 tttctcacgc tcttgatgcc accaccacga cgcgaataat atgcaggact gccaggttaa
     5281 tagatgtatg taaattcata acttaattct tcttttttgt ttcaaacgtg ctgcaaaggt
     5341 aagggctttt ttataatctc caaacaaatt gaagaaaaaa ataagataaa tatgaataat
     5401 cgtaagaaaa tatcgcccta aaatcctatt ttatcactta acagttctaa atagaaccat
     5461 tcagacagcc aatgtaaatg tattgccaat cattgaaacc atttaataat ctgaaaatta
     5521 ccaaaggctc tctacatccc gaaacaaata attcgtatct ttgtcatatg aagttacgaa
     5581 aaaggtctaa tttactggaa atgagcgtag gttaattg
//
