LOCUS       gnlProkkaHOJJOELN_2    16283 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|HOJJOELN_2.
ACCESSION   gnlProkkaHOJJOELN_2
VERSION     gnlProkkaHOJJOELN_2
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-12-02 05:43:43
            Original ID  :: gnl|Prokka|HOJJOELN_2
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 80984
            Orig. end    :: 97267
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..16283
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="True"
                     /core_location="[10000:10900]"
                     /cutoff="20000"
                     /detection_rule="(Terpene_synth or Terpene_synth_C or
                     phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7
                     or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..10900
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(Terpene_synth or Terpene_synth_C or
                     phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7
                     or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     cand_cluster    1..16283
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Terpene_synth or Terpene_synth_C or
                     phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7
                     or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..16283
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="terpene"
                     /region_number="1"
                     /rules="(Terpene_synth or Terpene_synth_C or phytoene_synt
                     or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps
                     or fung_ggpps2 or trichodiene_synth or TRI5)"
                     /tool="antismash"
     CDS             2464..2970
                     /locus_tag="ctg2_69"
                     /transl_table=11
                     /translation="MVSLSGICLLKGETVPQKTEWKGGRLIYDGVIIKNQFNLPQKGIK
                     YHDEDRLSYDVMDTTIEMSTTLSKNPQCGREWCYKGISHIVVKYSGPISDPIDGGTIYF
                     EPYYNHHIWFDKKKYGEWGILYSKVYIITRIKNANIEDVRDYGISGEDGSIFFQYVEKV
                     VDDNM"
     CDS             complement(3310..5307)
                     /locus_tag="ctg2_70"
                     /transl_table=11
                     /translation="MKFIIPALALSACLPAAFSQEQIIPKPAEITLFTGSPARLTPDSL
                     IITETQDKAFLDQAGQLQQMLSAGTGLPLPLKPAGQASKKAACIVIKKDPALAARGEEA
                     YSIQSSPSGIILSAADARGIFYAGQSLVQMMPSVFHDRTADKSAVRWNISETPFRITDY
                     PRFSWRALMIDEARHFFGEKTIKQIIDQMALLKMNILHWHLTDDTGWRIEIKKYPRLTS
                     IGSKRRESEIGTWNSGKSDGTPHEGFYTQEQIRDIVQYAARRNITIVPEIEMPGHASAA
                     AVAYPFLSLKTPGEVPTTFIVNTAFDPTSEKTYYFLSDVLDEITALFPGRIIHIGGDEV
                     RYDKQWKGVPKIEEFMKKNGMKSYADVQMHFTNRMSGIIAQKGRRMMGWNEIYGHDVNG
                     DGGGKAGAKLDTNAVIQFWKGNTSLAKNAIRDGHDVINSLHTSTYLDYSYGSIPLQKAY
                     GFEPVFPGLEKQYHSRVKGLGAQVWTEWISTPERLHYQAFPRACAFAEVGWTPAGKKDF
                     PDFKKRLKAYSERMDLMGIKFARNVISQIDKSDFFNTPRIGTWTPATLTREEHSFDVTK
                     LVKASGKHTVTLLYDKGAHAIEIESVALYENSREVSRDAHAGRSGAHKENIQYILNAPA
                     PRQGATYTVKANFKGAGGRDSHGTVYFETP"
     CDS             5529..6323
                     /locus_tag="ctg2_71"
                     /transl_table=11
                     /translation="MTNMKMNTVILLSLAACTGMLACPGAWATAVCQEQSYHLKTACPH
                     PLSLAGPADERVYLRFQAGWASKYECEGLDLWDGSLCMFVPEIQYKEWVGKIWYGVSTD
                     HRNHAELKYRLDYVRELGNWTVMPWYEHSFVFPGDKGIPRPGLKTTYHFSDRWFGGADL
                     YWQYNNHTFRGYYAVFAGMHEEIADCVRVDAIVRYGYNGGYVGPVVHHGSNALDYNLSV
                     TFRATGRLTVELFTNYSQALTVVKQKGLGDDFYYGVNLKYTF"
     CDS             6493..8280
                     /locus_tag="ctg2_72"
                     /transl_table=11
                     /translation="MNSPLPQSQPPDSVWYGWILKLFHHWKVGERQVTYVWAVLVGMVG
                     SCMSLFFEWMVEVIQWMLTGIWSDSRVGTFSLVEPEWRMFIPVAGGLVAGCILLFLKKR
                     MPGQATEYMEAMSIGNGLIKFRASALKVFSAAWSIASGAAIGKEGPIIQSSALIASTVG
                     QHLHVSIPRLRLLVGCGAAAGFTTAFHAPFSGCLFVSEIIIGTVSMDILAPLLIASCTG
                     FVMLHLLGDPSPLYSSPFESFSVFSQSLWCIALGAAAAVAARGWVSLLDAAARYLNGRQ
                     SLLPLRLAAAGLVVGILAVFYPEVVGNGQALITGLVHEDYGTREALVLLLVKVSAVAVV
                     FGCGTVGGAMTPTLYVGSMVGFIFSTVLTSLGMEGNHTVAYAMVGMASFFAVAAQAPLT
                     ALVMVVEFSMSGQMIYPLLIGVVSAYGTGKLIRARSMYAASLAGSPASVVNLPMAQVHV
                     HDLARHVVPQVAPDASLDDVSSLMLRNPGDLVFVVNKDGIYEGAIYPEDFLAVRRQMEV
                     RKGAVPADAGALVRTGAPVLDAGTHLTDALKLFEQTHLPAFPVVWKNTGRLDGVLYRNA
                     LFQVITEMMKRESGGDVGM"
     CDS             8478..10004
                     /gene_functions="regulatory (smcogs) SMCOG1112:sigma-54
                     dependent trancsriptional regulator (Score: 426.3; E-value:
                     2.6e-129)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg2_73"
                     /transl_table=11
                     /translation="MNEINRSPDLEMVVLKEISSAIVNERNGTALLRHILDVLYRRMKM
                     LRGTFTIRRGNDLMIEASHGLDEQEMKRGHYHVGEGITGHVAETGRPHVIEDISRDSRF
                     LNRTRTRKSGERVAFICVPIIHLQQVIGTLSIDRAVDRDTDLERDQKLLEIVGNIVGDA
                     LAASLQAHEERAALVAENEKLRELLTTNPGELIGNCSTMLQVYEQIRQVAPSDATVLIR
                     GSSGTGKELVARAVVNLSGRKDKPLVTLNCAAMPENLLESELFGHEKGSFTGATSRRIG
                     RAEAADGGTLFLDEIGDLSLQMQVKLLRFLQEKTFSRVGSNRELHADVRFIAATSRNLE
                     ELMAASKFREDLYYRLNIFPIVMPDLSKRKGDVMLLAEHFLSKFNLKYGKDIKRLSTPA
                     INMLMAYHWPGNVRELENCMERAVITAQDDCIYGYNLPASLQMPSHDVPYSRDGEAPAD
                     LPTMVDSFERELIVAALKRSPGNMSAAARELGISPRVLHYKMHRLGLQKS"
     CDS             10001..10900
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: phytoene_synt"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg2_74"
                     /sec_met_domain="phytoene_synt (E-value: 1.3e-17, bitscore:
                     56.2, seeds: 8, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKGLDHLLSAVSRSFYLSMRFLPREMRPGVAVGYLLARATDTVAD
                     AVDMDCRERLALLRMMGETVAGSASREVAATCFGRLGVLSTIQTHRGEAELLARFPECL
                     ALLENLSPHERMLVRQVLASIVEGQAWDLMYFESHAAVSCPEQLEHYTYMVAGCVGEFW
                     TRLGLLAQGPGFSTQPEEQLLRWGRHYGMGLQLVNILRDREEDLARGRSYLPAPDDRPW
                     LDRAERWLKEGVFYAESLRNGRLRFSTVLPAWLGLDTLELLQRADRRHPSSGKVKIARG
                     DVYLRMWKAFLFSWKEAL"
     CDS             complement(10902..12482)
                     /locus_tag="ctg2_75"
                     /transl_table=11
                     /translation="MKAHRRRIPRLTWFKLAVCICLAAMAASLFTPYPAQIIRALKGAP
                     EQAPPDSGTCPPQKSPPAEQPGQEEQPITAAPSASGKEPGDERLYTPWTPERTIALPPV
                     QYPPFPPVLPTRPAEGAMTHIYELARGLNLKTQVNFQPGTLASRDRETKSNYQMTLSLN
                     VKQPKALTKKEDMLKLNPKLEPMLPGLSTLFRHARVSPYYGQIYVRKQTEIRKNLASLL
                     KLLDRHNYYDTETILETTYPDTGRKLLWLQSEMDVVSDGSDGDRLAAMPDKILKSSFYQ
                     PSTSYRWKKRTDKPNPLLKPWQQRLASYKKTLEKAPAAEKTALRRKIDHAERVIEELKR
                     YSFLISEYDPFIVVPLGVVNQSTPFSPQFGDYAVVIVGDKLYPALVGDAGPRYKTGEGS
                     LRLSREINPKAGPYSRPVSDLKVSYLIFPGSAEPEAGPPDYEKITDRCQELLNEIGGVG
                     KGFNLHQWEDLLAPKPPPAPKPESGGTAETPANKRKKEEAPGNKPAPAPAPPASPQTAP
                     ASSAAKSAA"
     CDS             complement(12479..13324)
                     /NRPS_PKS="Domain: PKS_KR (11-175). E-value: 5.3e-14.
                     Score: 44.4. Matches aSDomain:
                     nrpspksdomains_ctg2_76_PKS_KR.1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001:short-chain dehydrogenase/reductase SDR (Score:
                     160.5; E-value: 8.3e-49)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg2_76"
                     /sec_met_domain="adh_short (E-value: 6.8e-32, bitscore:
                     103.2, seeds: 230, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MHTARLQYDRIIITGASSGFGEAFAGTLAPHTAELVLIARNEAAL
                     RQLAAALEKRHSGLHASVLPCDLADEASLNMLISRLDSLPPGRTLLINNAGAGDYGDFS
                     DGRWEKIRFLLRLNVESLTRLCHALVPSMKRNGGDIINLSSLGALLPIPDFAVYAATKA
                     YVSSLSEALRLELREHGIRVLVVCPGPVSTGFGKAARRPGFTGNMMPGRNAFDTSVETV
                     VKDSLRALARGRARVFPGMKIRLAAMLLAAAPLGLIRLFMGRRPRKVLPASNDSPSSAS
                     "
     aSDomain        complement(12800..13291)
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg2_76_PKS_KR.1"
                     /evalue="5.30E-14"
                     /label="ctg2_76_PKS_KR.1"
                     /locus_tag="ctg2_76"
                     /protein_end="175"
                     /protein_start="11"
                     /score="44.4"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C2"
                     /tool="antismash"
                     /translation="IITGASSGFGEAFAGTLAPHTAELVLIARNEAALRQLAAALEKRH
                     SGLHASVLPCDLADEASLNMLISRLDSLPPGRTLLINNAGAGDYGDFSDGRWEKIRFLL
                     RLNVESLTRLCHALVPSMKRNGGDIINLSSLGALLPIPDFAVYAATKAYVSSLSEALRL
                     E"
     CDS             complement(13560..13982)
                     /locus_tag="ctg2_77"
                     /transl_table=11
                     /translation="MDILVSTLCDFAADYQGKLCIQGGFDSLVARQFPVVHPVCAVALR
                     ICLTPEDEGTHELGLSIVDADGTPLDKERMPIKINFPVPAFPEGASFFTRNLIMNFQGL
                     RFEKPGNYSIDLTVDGELASRVPFRVVQVQEEAAQA"
     CDS             14126..16282
                     /gene_functions="transport (smcogs) SMCOG1000:ABC
                     transporter ATP-binding protein (Score: 137.1; E-value:
                     1.3e-41)"
                     /gene_kind="transport"
                     /locus_tag="ctg2_78"
                     /transl_table=11
                     /translation="MGRESLYYCSGNAFPGMIQWFFDIPSKLIHWRLNLVRALGAYVPW
                     LRRDDGSMKVHAGTLVDLFATILSGRRHLSARDADAALDILRYTFPEVEHRWLSNRFER
                     SMRASLTVADVLASAASGRDETERMAIALEVLSLLINTGDSRMTGELFDQVTYGLELPG
                     TANHLRQLLMTPDVEAQEPAYSVGFSSGIGAEVSLPEQDKGISFRLIRCSRLVLVVNDG
                     TRPIVVRGRHLQPGGVMPLTNGQVVLLPSGPLSFEDFAFFLDCKRSGKQEVCYISLDGG
                     SLQISRVRSRASEVRVNMGLACEVEVLRPEVEFAVDGRRLYPGESVRMAYYSSFTLDGE
                     GPFSMGEVQNSMSDIGRRFRLDPGNRKLRVTNLPEKARKGDMLLTPGLAPGAVLEVSFS
                     SATNSGWLEVVEASMPLLLNGRPVRGRVSLRDGDVVHLNAYHALRCRFSAGVLDEEYHA
                     IRTLSVEGVTKEFLRSGRVLDNIDLTVKRGEMVCILGPSGSGKSTLLSMLAGQLPPTRG
                     CIRYNNQLLYSAPDLIRPYIAFIPREDILDAAMSVSEHISQATMIRRPRLSRSERVRRV
                     NAILKFLGLTHIASRRVGEMNARTISDGERTRLNLGLDLAGIADVFLLDEPISGLSTSD
                     AKLVMQTMQNMSRDKMVIATMHRPSTAILNQFHKVLVLDHGGQMAYWGDVPGMMRYFRK
                     AAADMAIDVSEEARTAGGADYVFEV"
ORIGIN
        1 gctggtagct ggcgacggct ccatctgggc tgtaggagaa aaagaaagca tttaccgcct
       61 tcagattggg gaccggacat atgaaaaatc gtggcttaat atggattatt attccggttt
      121 ccccaaagga aagaatttca cctgtatcgc ggaggacagg caggggcgca tctgggcggg
      181 cacggatgac agcggcgtag ccgtttttaa cggaagggaa tggaagatgt atgaccgcag
      241 caatgccctg aatggagagc atgtttatgc tttggccatt tctcccgttt ccggggaggt
      301 ggccgtcgcc acatccggag gcgtatccat ttacgatcct gcaggcgatt catggaagac
      361 gctggatagg tccaccggcc tggtggaaga ccaggcggct tccgcaggtt ttgataccag
      421 ggggaatttg tggctggcct atgcttgcgg cggggtatcc tgctcttcgc accagtcaaa
      481 gtatatgcag tggaaaaatg ttcaggctcc ctggtactgg gataacaggc aattcgcccg
      541 tcagccgtac cagccgtatg gtgatggttt gccttccaat atctgcaatg ttttgacttg
      601 tacggataag ggccaggtgt tggtaggtac ctgctcaggc ttggcgtaca gtaacggcat
      661 tagttcttgg cgttatatga gagggcgtga ttatgcccag aaaaacaacc atctgtatgg
      721 ttctgccgca cggaagactg cggtgccggg ggagtcgaat tccagaatgt tgtctgaaga
      781 ttttatttct tccattatcc agcagggaaa ggaaattttc atcggctacc ggatgcaggg
      841 agtggatgtt ctggatgctg aaaaaatgac ggtgaatcag agaataagga aggggctgga
      901 aaacgtggat gttccttcct tgctggcgct tcaggacggg agtgtttggg cggcgacata
      961 cggacggggc tttgttcgtc tgaaaaaggg gactctggct tataaactgg acagggaaca
     1021 gatggacaat gaagtcccgt tccctcgtcc ggcgcagatg gaggagcctt ctgtggtgct
     1081 cagaaggttg gaaaggctgg ggtccgatgc gcatgcgggg aagaatattg tgttccgggg
     1141 ggaggactgg actacaaaag gggactggtg cgggaagtac gggcacacgc gtgccacgct
     1201 gtgcgccacg aatgccccca tgagcaattc cgaattcaaa gccaagccta ttaagttccg
     1261 tactctttct tccgttcccg gacatcccgg atacaagggg gccttgtctc cctactggat
     1321 tcaggggctg atggggctca accgcaagaa aggggacgct ttgcgctggt gggtgcacag
     1381 catcaaggaa aatgataacc gcaacgttct tttcgaccct acggattccg tgcggacaga
     1441 ggcggagtgg gatgaccacg gagaagtgta tccgggcttt gtggacggac ccgatatatg
     1501 ggtagccgta gaggtgccgg aaggtgtcca tgaaatagcc ctgtattttt acaatcccaa
     1561 cggttatctc accaatgaat ccaggcggga ttacgtggtg gaagccagaa ggcacccttc
     1621 caccgctccc cttgtgttcc agttcaatat tgagggggat cttgcgatag gagaacagaa
     1681 taattggggg aaggaacttg ctgcatccat ggagcagtgg tattcctacc cggtggaggc
     1741 gcgcacacgc gtttccagat ttgcggggtc cggggtttat aaaaggttca tgagcaggaa
     1801 aggggggatt tacctgttcc gtatttgccg gaacggttcc tttaatacca ttttaaacgg
     1861 cgtgtttgtg aatgaaaaaa taccgtggga aattcgaatg cctgaggaac tgccttatta
     1921 cgtatccggt gctctggccg gtattgtccc cactccggaa agggtgagtg gagctactct
     1981 gggacagagg gaaaaggctg tgtgcaagcc tctgtatgag ttgcagtata cgcgcaagta
     2041 ccttactccg gctgcgtgca gtcttcagaa caggtatatt ctttccctgt ggcggcaggc
     2101 ccggaagagt cgggccgagg gtggttgtct ggcggactgc ctccagtggg aagccagagt
     2161 aagcgacgac cgtgtgagag cttccttcga tgagaccatg aagcgttctt gggagcagag
     2221 ccagatttat tatattggca acaggtcccg ggatttcatg ccgaatgccc cgggtactgt
     2281 tcctttttct ctcagcgaat tgcgcctgat ggccaagctg cgcatcgact ggaggcagta
     2341 tcgggacgat gcgaagaccc ctcctgaaaa aactgttcag gaaatgaaag aattcctcaa
     2401 taaggaattg ctgaaacaac aacaaagtag aaaataacaa tgaataaaat tgcctgtgca
     2461 ataatggttt ctctctcagg aatctgtctc ttgaaagggg aaacagtgcc gcagaagacg
     2521 gaatggaaag ggggacgtct catttatgat ggagtcatca tcaaaaatca gttcaatctg
     2581 cctcaaaaag gaatcaaata ccatgatgag gataggttgt cctatgatgt catggacacc
     2641 accattgaaa tgagcaccac cctttccaaa aatcctcaat gcggcaggga atggtgttac
     2701 aagggaatca gccatattgt tgtcaaatat tccggcccga tttccgatcc gatagacgga
     2761 ggcaccatct attttgaacc atactataac caccatatct ggtttgataa gaaaaagtat
     2821 ggggaatggg ggattttgta ctccaaagtc tatattatta cccgaatcaa gaatgcgaat
     2881 attgaggatg tcagagacta tggaatcagc ggggaggacg gaagcatctt tttccagtat
     2941 gtggaaaaag tggtagatga taacatgtaa attccgtctg gctttcccgg atgaaaatca
     3001 tcttccgccg attcacggtt gttcaggttc cggaggttcg caagcaacga cctccggagc
     3061 cttgttaagg caaggctgat ttcagggtaa gcctttctgt gggttaaagt atcaatttcg
     3121 tgccacctga tggaaagggg cgtcttcctc tatgaaaaga catgccggcg cccttgggag
     3181 gccaatgata ctgaaaggct cgtgtccgta accatgagtc tgcggatgct gtgctccgtt
     3241 tgttggagta aagggggctc tgtgtgaagc cccccctgct gtttctggta tggggcgggg
     3301 gcggtgtttt tatggcgttt caaaatacac tgtcccgtgg gaatcccggc ctccggcccc
     3361 tttgaagttt gctttgaccg tataggttgc tccttgccta ggggccgggg cattcagaat
     3421 gtactggata ttttccttat gggcgccgct tctgcctgca tgggcgtccc gggagacttc
     3481 ccgggaattt tcatacaggg ctacggattc gatttcgatg gcgtgggcgc ctttgtcgta
     3541 cagcagggtg acggtgtgtt tgccggacgc tttgaccagt ttggtaacgt caaacgaatg
     3601 ttcctcccgg gtcagggtgg caggcgtcca tgtgccgatc ctgggcgtat tgaaaaagtc
     3661 agatttgtct atttggctga tgacgttccg ggcaaacttg atccccatca gatccatacg
     3721 ctcgctatac gctttcaagc gttttttgaa atccggaaaa tcctttttac cggcgggagt
     3781 ccagccgact tccgcaaagg cgcaggcacg ggggaatgcc tggtagtgca ggcgttccgg
     3841 tgtggaaatc cattccgtcc atacttgggc gcccagtccc ttgactctgg aatggtactg
     3901 tttctccaac ccggggaaaa cgggttcgaa cccgtatgcc ttttgcaggg gaatgctgcc
     3961 gtagctgtaa tccaaatagg tggaggtgtg gagggaattg ataacgtcat gcccgtcccg
     4021 gatggcgttt ttagccaggc tggtgttgcc cttccagaac tggatgacgg cgtttgtatc
     4081 cagtttggcg ccggcttttc ctcctccgtc cccattgacg tcatgtccgt aaatttcatt
     4141 ccatcccatc atgcggcgcc ctttttgggc aataatgccg gacatgcggt tggtgaaatg
     4201 catctggacg tccgcataac ttttcatgcc gttttttttc atgaattcct caattttcgg
     4261 aacccccttc cattgcttgt catagcgcac ctcatctccg ccaatgtgga tgattctgcc
     4321 ggggaagagt gccgtgattt catccaaaac atcggacagg aagtaataag ttttttccga
     4381 ggtgggatcg aaggccgtat tgacgatgaa tgttgtgggc acttccccgg gagttttcag
     4441 gctcaggaag gggtatgcta cggcggcggc gctggcatgg cccggcattt caatttccgg
     4501 aacgatggtg atgtttcggc gggctgcgta ttgtacgata tccctgatct gttcctgggt
     4561 ataaaagcct tcatgcggcg ttccgtctga cttgccgctg ttccatgtgc cgatttctga
     4621 ttccctgcgt ttggagccga tggaggtcag gcgcggatac ttcttgattt caatgcgcca
     4681 tcctgtgtcg tccgtcaggt gccagtgcag gatgttcatt ttcagcagag ccatttggtc
     4741 gatgatctgt ttaatggttt tctcgccaaa gaagtggcgt gcttcatcaa tcatcagagc
     4801 ccgccaggag aaccgcgggt agtccgttat gcggaacgga gtttcagaaa tattccaccg
     4861 gacggcggat ttatccgccg tccggtcgtg gaagacggag ggcatcatct ggaccaggct
     4921 ttgccccgcg taaaagatgc ccctggcatc ggctgcggaa aggatgattc cacttgggga
     4981 tgattggatg gagtaggctt cttctcccct ggcggccagg gctgggtctt ttttgatgac
     5041 aatgcaggcg gcttttttcg acgcttgccc ggccggttta aggggaaggg ggagtcccgt
     5101 ccctgcgctg agcatctgct gcaattgccc tgcctgatcc aggaaagctt tgtcctgtgt
     5161 ttccgtgatg atgagggaat ccggtgtgag acgggccgga cttcctgtga acaatgtgat
     5221 ttccgccggt ttcgggatga tttgttcttg tgagaaggct gcgggaaggc aggcggacag
     5281 ggcgagtgcg gggataatga atttcatgga cacggttata agtacaaaga ctgctgacac
     5341 aatctttcat ggggaattcg tttttttggc tcttggaact gaatattgtt ttttcatgct
     5401 ggtctcatct ttagaaggta tttgtccggg tgagggcgta gtatccgttt acggctaaag
     5461 cgggatgcgg gtacgcatgg gtggatggcg ccgcttccgg atatgccgtt tcagaaaaat
     5521 ttccagccat gaccaatatg aagatgaata ccgtaattct gttgtcgctg gcggcctgca
     5581 ccggcatgct ggcgtgtccc ggagcctggg cgacggcggt ctgccaggaa cagtcctacc
     5641 acctgaagac ggcatgcccc cacccccttt ccctggccgg tcctgcggat gagcgtgttt
     5701 atttgcgatt tcaggcgggg tgggccagca agtacgagtg cgagggcttg gacttgtggg
     5761 acggttctct ctgcatgttt gttcctgaaa tacagtataa agagtgggtg gggaaaatat
     5821 ggtacggcgt ttccacggac caccggaatc atgcggagct gaaataccgg ctggactacg
     5881 tcagggaatt gggcaactgg acggtcatgc cctggtatga gcacagcttt gtttttccgg
     5941 gagataaggg aatcccgcgt cccggattga aaacgaccta ccatttttcc gaccgctggt
     6001 ttggcggcgc ggacctgtac tggcagtata acaaccatac gttccgcggt tattatgccg
     6061 tatttgcggg gatgcatgaa gaaatagctg attgcgtgcg ggtggatgcc atagtgcgct
     6121 acggttacaa tggggggtat gtaggcccgg tggtgcacca tggttccaat gctctggatt
     6181 ataatctgag cgttaccttc cgtgctaccg ggcgcctgac tgtggaattg ttcaccaatt
     6241 acagccaggc gctgaccgtg gtaaagcaaa aggggttggg ggatgatttc tattacggcg
     6301 tcaatttgaa atatacgttc tgactaccgg tgcggggcca ggccccgaag gggggcccgt
     6361 aagagccgtc tgcgtatccg ttgaaaatct tctctggctc cggaggggca tggggctggg
     6421 cagttttttc ttccgtatcg aacagccgga ggtatttttt tgtcacaatg gaatagtatt
     6481 gccttctttt ctatgaattc tccactcccc cagtcccagc cgccggattc cgtctggtac
     6541 ggatggattt taaaactgtt ccatcattgg aaggtggggg aaaggcaggt tacttatgta
     6601 tgggccgtgc tcgtcggcat ggtgggctcc tgcatgtctc tgtttttcga gtggatggtg
     6661 gaagtgatcc agtggatgct caccggcatc tggtcggatt cccgcgtagg aaccttttcc
     6721 ctggtggagc cggaatggcg catgtttatt ccggtggcgg gcggcctggt ggccggctgc
     6781 attctgctgt tcctgaagaa aaggatgccg gggcaggcta cggaatacat ggaggccatg
     6841 tccatcggga acgggctgat caagttccgg gcctccgccc tgaaagtttt ttccgcggca
     6901 tggagcatcg cttccggcgc ggccatcggc aaggaagggc ctatcatcca gtcttccgcc
     6961 ctgattgcgt ctaccgtggg gcagcatctg cacgtatcca ttccgcggct ccggctgctg
     7021 gtcggctgcg gagcggcagc cgggttcacg acggcgttcc atgccccttt ttccggctgc
     7081 ctgttcgtga gtgaaatcat catcggcacc gtgagcatgg atattctggc ccccctgctc
     7141 attgcctcct gtactgggtt cgtgatgctg catctgctgg gggatccctc ccctttgtac
     7201 agttccccgt ttgaaagctt ttctgtcttt tcccagtctc tctggtgcat cgccctgggg
     7261 gcggcggcgg ccgtggcggc caggggatgg gtcagtttgc tggatgcggc cgccagatat
     7321 ttgaatggcc gccagtccct tctgccgctg cgtttggcgg ccgccgggct ggtcgtgggg
     7381 attctggccg ttttttatcc ggaagtggtg ggcaacggtc aggctctcat taccgggctg
     7441 gtccatgagg attacggcac gagggaggcg ctcgtcctgc ttctggtgaa ggtgtctgcc
     7501 gtggcggtgg tgttcggctg cggtacggtg ggcggagcca tgacgcccac cctgtacgtg
     7561 gggagcatgg tgggttttat cttcagtacg gttctgacgt ccctgggaat ggagggcaac
     7621 catacggtgg cgtatgcgat ggtggggatg gcgtcctttt tcgccgtagc tgcccaggcc
     7681 cccctgacgg ccctggtgat ggtagtggag ttttccatga gcggacagat gatttatccc
     7741 ttgctgatcg gtgtcgtaag cgcttatggc acgggaaaac tgattcgcgc gcgttccatg
     7801 tatgccgcca gcctggccgg cagtccggca tccgtcgtca acctgcccat ggcgcaagtc
     7861 catgtgcatg acctggcgcg gcacgtggtg ccccaggtgg ccccggatgc ttccctggat
     7921 gatgtctcct ccctgatgct gcggaatccc ggagatctgg tttttgtggt gaataaggat
     7981 ggaatttatg aaggggccat ctatccggag gactttctgg cggtccgccg gcagatggag
     8041 gtgcggaagg gggcggttcc ggccgatgcc ggggccctgg tccgtacggg ggctcccgtg
     8101 ctggacgccg gcacccattt gacggatgcc ttgaagctgt ttgaacaaac ccatctgccc
     8161 gcctttcccg tggtctggaa gaataccggt cggctggacg gcgtgctgta ccgcaacgcg
     8221 ttgttccagg ttatcacgga gatgatgaaa cgggagtccg gcggagacgt gggcatgtaa
     8281 aacggaacga gacaagggat gtgtattaca tttttgtaaa aatcttttgt tccccgttcg
     8341 taatatcatc aacattaatt gctgggatgt tatccatatt ccccgtgccg tttttttgtc
     8401 cgggtgcatg gcggtggaag aaaaagtagt tggtatggcg ggggcgtgcg gttaatattc
     8461 gcccagcccc ggattgcatg aatgaaataa acaggtcacc ggatttggag atggtcgtgc
     8521 tgaaagaaat cagttccgcc attgtcaatg aacgcaacgg cacggctttg ctccggcata
     8581 ttctggacgt gctttaccgc cgcatgaaaa tgctgcgcgg cacgttcacc atccgccgcg
     8641 ggaacgattt gatgattgaa gcctcccacg gcctggacga gcaggaaatg aaacgcggcc
     8701 attaccatgt gggggaaggc attacggggc atgtggcgga aacgggcagg ccccatgtga
     8761 ttgaggatat ttcccgggat tccaggttcc tgaaccgtac ccgcacgcgc aaaagcggtg
     8821 aaagagtagc cttcatctgc gttcccatca ttcatttgca gcaggtcatc ggcacgttga
     8881 gcattgaccg tgccgtggac cgggacaccg acctggaacg ggatcagaaa ctgctggaga
     8941 ttgtaggcaa tattgttggg gatgctctgg ctgccagcct ccaggcgcat gaggaacgtg
     9001 ccgccctggt cgcggaaaat gaaaaactgc gggagctttt gacgactaat ccaggcgaat
     9061 tgatcggcaa ttgcagcact atgctccagg tgtatgaaca gatccgccag gtggcgccca
     9121 gcgatgccac ggtgctgata cggggaagtt ccgggacggg gaaggaactg gtggcgcgcg
     9181 ccgtggtgaa tctgagcggc agaaaggata agccgctggt cacgctgaat tgtgcggcca
     9241 tgccggagaa cctgctggaa agtgagctgt tcggtcatga aaagggttct tttaccgggg
     9301 ccaccagccg ccgcatcggc cgggcggagg cggcggacgg cggcaccctg tttctggatg
     9361 aaatcgggga tttaagcctc cagatgcagg tgaagctgct gcgctttctt caggaaaaga
     9421 ccttttcccg cgtgggaagc aacagggagc ttcatgcaga cgtgcgcttc atcgccgcca
     9481 ccagccgcaa tctggaggaa ctgatggcgg cgagcaagtt ccgggaagac ttgtactacc
     9541 ggttgaacat tttccccatc gttatgccgg acctctccaa acgcaagggg gacgtcatgc
     9601 tgctggcgga acattttctt tccaagttca acctgaaata cggaaaggat atcaaacggc
     9661 tgtccacccc cgccatcaac atgctcatgg cttaccactg gcccggcaac gtccgggagc
     9721 tggaaaactg catggaacgt gccgtcatta cggcgcagga cgactgcatt tacggttaca
     9781 accttcccgc ctccctccag atgcccagcc atgacgtccc ttattcccgt gacggggagg
     9841 ctcccgccga tttgccgacc atggtagatt cctttgaacg ggaattgatt gtagccgcat
     9901 tgaaacgttc tccgggcaat atgtccgccg cggcccggga actgggcatt tccccgcggg
     9961 tactccatta taagatgcac aggctgggcc tgcagaaatc atgaaaggcc ttgaccatct
    10021 tttatcggcc gtctcccggt ccttttatct gagcatgcgc ttcctgcccc gggaaatgcg
    10081 ccccggcgtg gccgtgggct atctgctggc gcgtgccacg gatacggtgg cggatgccgt
    10141 ggacatggat tgccgggagc gcctggcgct tttgaggatg atgggggaga cggtggccgg
    10201 ctctgcctcc cgggaggttg ccgccacctg ttttggccgt ctgggcgttc tttccacaat
    10261 ccagacgcac cggggggagg cggaattgct ggcccgtttc cccgaatgcc tggcgctgct
    10321 ggaaaacctt tccccgcatg aacggatgct ggtgcggcag gtgctggcct ccatcgtgga
    10381 gggacaggcg tgggatttga tgtattttga aagccatgct gccgtctcat gcccggaaca
    10441 actggaacat tatacttaca tggtggccgg atgcgtaggg gaattctgga ccaggctggg
    10501 cttgctggcc caggggccgg gcttcagcac gcagccggag gagcagcttt tgcgctgggg
    10561 caggcactat ggcatggggc tgcagttggt gaatatcctg cgtgaccggg aggaagacct
    10621 cgcccgcgga agaagctatt tgcctgcccc agatgaccgt ccatggctgg accgcgcgga
    10681 acgctggctg aaggaaggcg tgttttacgc ggaatctctg cggaacgggc ggctgcgttt
    10741 ttccaccgtc ctgcccgcct ggctggggct ggacacgctg gaactgctcc agcgggcgga
    10801 tcggcggcat ccatcttccg ggaaggtgaa gattgcgcgc ggagacgttt atttacggat
    10861 gtggaaagcc tttctttttt cctggaaaga ggctctgtag cttatgcggc gctttttgcg
    10921 gctgatgaag ccggagcagt ttgcggggaa gccggcggag ccggggcagg ggcaggcttg
    10981 tttccggggg cttcctcctt tttccgctta tttgcaggtg tttccgctgt gccgccgctt
    11041 tccggttttg gggcgggcgg tggcttgggc gccagcaggt cttcccactg gtggaggttg
    11101 aatcctttcc ccacgccgcc tatttcgttg agaagttcct ggcatctgtc cgtaattttt
    11161 tcatagtcgg gaggcccggc ctcgggctct gcggaaccgg ggaaaatcag gtaacttacc
    11221 ttcaggtcgg agacggggcg gctgtaaggg cccgccttgg ggttgatttc acggctcagg
    11281 cgcagggaac cctccccggt tttgtagcgc ggcccggcgt ctcccaccag ggccgggtac
    11341 aacttgtctc ccacgatgac gacggcatag tccccgaact gcggggagaa gggagtggac
    11401 tggttgacga ctcccagcgg aaccacgatg aacggatcgt attccgagat caggaagctg
    11461 taccgcttca gttcctcaat gacccgttcc gcatggtcta ttttgcggcg cagagccgtt
    11521 ttttccgcgg cgggggcttt ttccagcgtc ttcttgtagg aagccagcct ctgctgccag
    11581 ggtttgagca ggggattggg cttgtctgtg cgctttttcc agcggtaaga agtgctgggc
    11641 tgatagaagg agcttttcag gattttatcc ggcatggcgg ccagccggtc cccgtccgag
    11701 ccgtcggaaa caacatccat ttcactttgc agccagagaa gcttccttcc cgtgtccgga
    11761 taggtggttt ccagaatcgt ctccgtatcg taataattat ggcggtccag aagtttgagc
    11821 agggaggcca ggtttttacg gatttccgtc tgtttgcgga cgtaaatctg cccgtagtaa
    11881 ggggagacgc gcgcatgcct gaacagggtg gacaggccgg gaagcatggg ttccagtttc
    11941 ggattgagct tcagcatatc ttcctttttc gtcaatgctt tgggctgttt gacgttcagg
    12001 gaaagggtca tctggtaatt gcttttggtt tccctgtccc tggaggccag ggtgccgggc
    12061 tggaaattaa cctgcgtttt caggttcagt ccgcgggcca gttcataaat atgggtcatg
    12121 gccccttccg caggccttgt gggaagcacg gggggaaatg gggggtactg caccgggggg
    12181 agggcgattg tgcgctccgg cgtccatgga gtgtacagcc gttcatcccc gggttccttt
    12241 ccggaggcgg atggtgcagc ggttattggc tgttcttcct gcccgggttg ttccgcgggg
    12301 ggggatttct ggggcggaca ggttccggaa tccggcggcg cctgttccgg cgcccctttc
    12361 agggcgcgta tgatctgggc ggggtacggc gtgaacaggg aggctgccat ggctgccagg
    12421 cagatgcaga ctgcgagctt gaaccaggtg aggcggggta ttctgcggcg gtgcgctttc
    12481 atgatgctga agaaggagaa tcattggatg ccggcaggac tttccggggg cgcctgccca
    12541 tgaaaaggcg tatcagcccc agaggggcgg cggccagcag catggcggcc agtcgtattt
    12601 tcatgccggg aaagacccgg gcgcgtccgc gggccagggc acggaggctg tctttcacga
    12661 cggtttcaac ggacgtgtca aaagcgttgc gccccggcat catgtttccg gtaaagccgg
    12721 ggcggcgcgc cgcttttccg aaacccgtgg aaaccgggcc cgggcagacg accagcacgc
    12781 gtatgccgtg ttcgcgcagt tccagccgca gcgcttccga caggctggaa acataagcct
    12841 tggtggccgc ataaacggca aaatccggaa tgggcaggag ggctcccagg gagctgaggt
    12901 tgatgatatc tcctccgttc ctcttcatgg aggggaccag cgcatggcac aggcgggtga
    12961 ggctttccac gttcaggcgc agcagaaaac gaattttttc ccagcggccg tccgagaaat
    13021 ctccgtaatc accggcaccg gcgttgttaa tcagaagggt tcttcccgga ggaaggctgt
    13081 ccaggcggga aatgagcata ttcagggagg cttcgtccgc caggtcgcag ggaaggacgg
    13141 aggcgtgaag gcctgaatgg cgtttttcca gggcagcggc aagctggcgc agggcggctt
    13201 cattccgggc gatgagcacc aattccgccg tatggggggc cagcgttccg gcaaacgctt
    13261 ccccgaagcc ggatgatgcg cccgtaatga taatcctgtc gtattggagg cgtgcggtgt
    13321 gcatggcggg ttggagcagc ccgtatcatg gtcaatccgg tgcggaaccg caatgaaaaa
    13381 gggggaagga ggacgcaaaa agccggtctc ccttttttag gccggggcca ggcgcagagg
    13441 ttttcaggtg catggaaccg gggccggcct gttccgcact tccgggcgga cggccgctcc
    13501 aataaaaaac cgcctgccgg atgaacggga ggcggtttga tggaagaggg gatggtttct
    13561 taggcctggg cggcttcttc ctgcacctgc actacgcgga agggtacgcg agaggcgagt
    13621 tcgccgtcaa ccgtcaggtc gatggagtag ttgcccggtt tttcaaaacg caggccctgg
    13681 aagttcatga tcaggttgcg ggtgaagaaa gaggctcctt ccgggaaagc gggaaccggg
    13741 aaattgatct tgatgggcat gcgttccttg tccagcggcg tgccgtcggc atcaacgatg
    13801 ctcaggccca gttcgtgcgt accttcgtct tcaggagtga ggcagatgcg cagggcaacg
    13861 gcgcagacgg gatgcacgac cgggaactgg cgggcgacca gggagtcaaa gccgccctga
    13921 atgcagagct tgccctggta gtcggcggcg aagtcacaaa gagtagaaac taaaatatcc
    13981 atgttgtgat aatgttgatg tatttggcta gctttcacgc ggaaagcatg aacattggac
    14041 agaactatac ttcctctgga cctattgcaa gataaagctg tagaaaatat tgtcatttct
    14101 ccgtgaaatt ccggttgcgc ttgagatggg gcgggaatcc ctgtactact gttccggcaa
    14161 cgcgtttccg ggcatgatcc aatggttttt tgacattcct tccaagctga ttcactggag
    14221 gctgaatctg gtcagggcgc tgggcgccta cgtgccgtgg ctgcgccgtg acgacggctc
    14281 catgaaggtg catgccggaa cgctggtgga cttgttcgcc actattttga gcggacgccg
    14341 ccatttgagc gcccgtgatg cggacgccgc cctggatatt ctgcgctata ctttcccgga
    14401 agtggagcac cgctggcttt ccaaccgttt tgagcggtcc atgagggcca gcctgacggt
    14461 tgcggatgtc ctggcctccg cagcttccgg cagggatgag acggaacgca tggcgatagc
    14521 tctggaagtg ctttccctgc tgatcaatac gggagattcc cgcatgacag gggagctgtt
    14581 tgaccaggtg acgtacggtc tggaactgcc gggcacggca aaccacctga ggcagctgct
    14641 gatgacgccg gacgtggaag cccaggaacc ggcgtacagc gtcggttttt cctccggcat
    14701 cggtgcggag gtatcccttc cggagcagga caagggcatt tccttccgcc tgatccggtg
    14761 ttcccgcctg gtgctggtgg tgaatgacgg cacccgcccc attgtggtgc gcgggcgcca
    14821 tttgcagccc ggcggggtga tgccgctgac caacgggcag gtggtgctgc tgccgtccgg
    14881 tccgctgagt tttgaagact tcgcgttttt tctggactgc aagcgttcag gcaagcagga
    14941 agtatgctat atttccctgg acggcggctc cctgcaaatc agccgggtgc gttcccgcgc
    15001 cagcgaggtg cgcgtgaaca tggggctggc gtgcgaggtg gaggtgctga ggccggaagt
    15061 ggaattcgcg gttgacggga gacggctgta ccccggtgaa agcgtgcgca tggcctatta
    15121 ctcctccttc acgctggacg gggaagggcc tttctccatg ggagaggtgc agaattccat
    15181 gtcggacatc gggcgccgtt tccgcctgga tcccggaaac cgcaaactgc gggtgaccaa
    15241 cctgccggaa aaggcgcgca agggagacat gctgctgact cccggtctgg cccccggagc
    15301 ggtgctggag gtttcttttt ccagcgccac caattccggc tggctggaag tggtggaggc
    15361 ctccatgcct ctgctgctca atggccggcc tgttcgggga agggtttccc tgagggatgg
    15421 ggacgtggtg cacctgaatg cctaccacgc gctgcgctgc cgtttttccg ccggggtgct
    15481 ggatgaagaa taccatgcga tcagaaccct cagcgtggaa ggggtgacca aggaattcct
    15541 gcgctccggg cgcgtgctgg acaatattga cctgaccgtg aaacgcgggg aaatggtgtg
    15601 catcctgggg cccagcggat ccgggaaaag cacgctgctc tccatgctgg ccggccagct
    15661 gccgcccacc cggggctgca tccgttacaa caaccagctt ctgtacagcg ccccggatct
    15721 tatccggccc tacatcgcct tcattccccg ggaagatatt ctggatgcgg ccatgagcgt
    15781 ttccgaacac atctctcagg ccaccatgat acgtcgtccg cggctgagcc ggtcggaacg
    15841 cgtcaggcgc gtgaacgcta ttttgaaatt tctgggcctg acgcacatcg cctcccgccg
    15901 cgtgggtgag atgaacgccc gcaccatttc cgacggggag cgcacacgcc tgaacctggg
    15961 gcttgacctg gcgggcattg cggatgtttt cctgctggac gaacctatca gcggcctgtc
    16021 cacgtcagat gccaagctgg tcatgcagac catgcagaac atgagccgcg acaaaatggt
    16081 aatcgccacc atgcaccggc ccagcacggc tattctgaac cagttccaca aagtgctggt
    16141 gctggaccac ggcggccaga tggcttactg gggggacgtg cccggcatga tgcggtattt
    16201 ccggaaggcg gcagcggaca tggctattga cgtatccgag gaggctcgaa cggccggagg
    16261 cgcggactac gtgtttgagg tgc
//
