LOCUS       gnlProkkaEBBCKHAC_80   12063 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|EBBCKHAC_80.
ACCESSION   gnlProkkaEBBCKHAC_80
VERSION     gnlProkkaEBBCKHAC_80
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-12-02 02:21:39
            Original ID  :: gnl|Prokka|EBBCKHAC_80
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 12063
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..12063
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[9461:9728]"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      9462..9728
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
     cand_cluster    1..12063
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /kind="single"
                     /product="RRE-containing"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..12063
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="RRE-containing"
                     /region_number="1"
                     /rules="minimum(1, [Bottromycin_Methyltransferase_RRE,
                     Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /tool="antismash"
     CDS             178..1026
                     /locus_tag="ctg80_1"
                     /transl_table=11
                     /translation="MNISEFNINDEFIACNHITTNELNPLVEKPYHTKASIFALCTKGV
                     LKTIINHTQFRVEANALLVIPPETFVQLLHTSDDAEIYVVIFSQQLIQSSGAGKVMMDK
                     FHIIGKHYIFPLSRTDFQLYAEFMTYLSHLYQRTESPSSLVSLQTLLTYLLQGISELCP
                     ERPRIKETPGSRHFNQYRIFIRLVHTDYVREHQVSYYALKMNMRPAALCRLVKKESGYT
                     AMEIINNTIIMDAKAQLCTANTPIKDIAVSLGFNNAAFFNKFFKRHTGIPPQKFRTSSK
                     Q"
     CDS             complement(1101..1877)
                     /NRPS_PKS="Domain: oMT (51-145). E-value: 2e-11. Score:
                     34.4. Matches aSDomain: nrpspksdomains_ctg80_2_oMT.1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089:methyltransferase (Score: 81.3; E-value:
                     1.3e-24)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg80_2"
                     /transl_table=11
                     /translation="MSNENKTIHDFEFNLICDFFSNMERQGPGSPEVTLKALSFVDGLT
                     DESLIADIGCGTGGQTMVLAGHVPGQITGIDLFPGFIDIFNRNARQLGLQDRVKGIVGS
                     MDALPFGEEELDMIWCEGAIYNIGFERGLKEWRKYLKPGGYIAVSESSWFTDERPAEIN
                     DFWMDAYSEMDTLPNQVTKLYKAGYLPVATFILPENCWTEHYFASKVAAQEIFRKKYAG
                     NKIAEEFSLLQMIEDELYGKYKEFYGYVFFIAKKVG"
     aSDomain        complement(1443..1724)
                     /aSDomain="MT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg80_2_oMT.1"
                     /domain_subtypes="oMT"
                     /evalue="2.00E-11"
                     /label="ctg80_2_oMT.1"
                     /locus_tag="ctg80_2"
                     /protein_end="145"
                     /protein_start="51"
                     /score="34.4"
                     /tool="antismash"
                     /translation="DIGCGTGGQTMVLAGHVPGQITGIDLFPGFIDIFNRNARQLGLQD
                     RVKGIVGSMDALPFGEEELDMIWCEGAIYNIGFERGLKEWRKYLKPGGY"
     CDS             complement(2112..2444)
                     /locus_tag="ctg80_3"
                     /transl_table=11
                     /translation="MKQLIACCGLDCENCAARIATVNNDDELREKTAKEWSVLNNTPEI
                     TAETIHCMGCRADGVKFTYCSDYCAIRKCVYEKGFNTCGDCKELDTCQVVGAVLQHAPG
                     ARENLY"
     CDS             3310..3636
                     /locus_tag="ctg80_4"
                     /transl_table=11
                     /translation="MKNCYGIDFRSWHKELRTREKTKQPPCKLPDRASRSLQGVLFKVY
                     QISVLILLKKILFSFFSVCLPLFIRHIAAMLLRKTSSKTMQTVTKYLKELSGVRSDNSP
                     NSYK"
     CDS             complement(3780..3953)
                     /locus_tag="ctg80_5"
                     /transl_table=11
                     /translation="MFVYPLFRPSHCPFPGYTTVTHVVCVYTIPPDGRKPYKHRREHPC
                     CYLQGNFQSCEV"
     CDS             4002..4217
                     /locus_tag="ctg80_6"
                     /transl_table=11
                     /translation="MKQNTPDGREAYITPSIEVIKMENEGVIATSGEPYHPITRSYSGS
                     TSTHSYNSASSSDLEDLINDILTVEN"
     CDS             4231..7809
                     /locus_tag="ctg80_7"
                     /transl_table=11
                     /translation="MMKLRNLMQVACMATAALTAFSCSQEEFENSGWKGNITVNATFEG
                     AGTDTRTTVNDEYKILWQDTDALGLFCSNAESNYSNTKLEYASGAGQTSATFNGSKPSG
                     ETAVFSIYPYQQNMSVSGNTLTMTLPATLTNYNGSSNGPMYAKVTNPDNLSALSFKHMA
                     AMIKLTVNKIPAEATTFKIIASNNIAGTCTVDLTAADPILTVASNGSKEITASFTASND
                     IKSRNFYIPLPTGTYSSITAQLTNGSDKVYFTKTLNDKILGRRDILVVPPLDCVVVDAT
                     TPSALSTALADSKNLPQEAPTAATVTDIAVSGSFNTTSGSNDGIAIPVLQNSDINLTFN
                     TAPTTSTAAPLTLTDKTNTSVSAPAATATNSVSLAVPETTAEQEAPSVAITMPSTTVTL
                     AAVGNKATYNEVTATTAQQTLIINAGVTVKKLTVKGGNLKIYGKVEQLVHDAGDTTIYI
                     IKGTEASLPATIDSKFVVQSDVAVLKTAFANGEDFKLSADADITGQSVSVPAGKSVVLD
                     LNGYTLTADNSATGKIIVLGKMTLKDSSTEKKGKIVASQDYTAASYNGSLIEIAGEDAS
                     MTMESGNISAVRETPDSNGQYGVGVTDGGDFTMTGGKIEAGWFAVAGNGNYKTQNSIIN
                     ITDGELISTADYAVYLPQSGTTTISGGKVYGAAGGVCIQRGTLNVEGTALITSKGTGST
                     GNWGDGTGGLDCAAINVSGAYGIATVNIKGGTLIAEAKSLITEGTTYTPVINVTGGTFS
                     DPSALKYMKANANVNIKLTADKTCPGFKTTSGQTLTMDLGGKILTLADPTVGSTGTETN
                     SCQLLEGSNVTFKNGTLKSDNNKIMIQNYCNLTLDNMTVEDTNAQYVVSNNCGNISINN
                     TTINAGSNANQFAFDVCGYAKYTAGVTVTVSGTSVINGKVEISKSAGNTELMKLNITSG
                     TFNGDLKVDASVRTENAQSIISVSGGTFSDPSVLKYMATNATVDIKLLSNINIAKTKLA
                     TGYILNAANATANLNLNGHDIINSSETADATPFTQIFTVQNGTLNISGNGNVKCDASAT
                     AKDDGYRMVIEARGYGTVNIHGGSYYNTQKLNTQIDLIYARENGKINIYGGTFESGKYG
                     TPNNDTDGRYWVLNLKNTDKNTASIQVSGGTFINFNPANPNMDDNESYLVTGYEVTRDG
                     SVYTAAHKVGDGRKEYIVGQTSQENR"
     CDS             8056..8982
                     /locus_tag="ctg80_8"
                     /transl_table=11
                     /translation="MRIQILDYQVGPHTFRMVKPSDFNIFKALPSLIPFITTIDTTQKV
                     IFETEIDDDETTTKRTIAKTPDDICFNWEDADCIIRPLPHSSHLVSITPRKSGKNYWME
                     CNDNFRQCFIHLPACRTETPAPENETNFVLNNFLMMLYAFNAARHHTLLMHASVVATET
                     GKGYLFLGKSGTGKSTHTGLWLQQFSDCHLLNDDNPIVHVDSLGKQATVFGSPWSGKTP
                     CYRKESMTVGAFVRLEQAPQNEIEQERAAHAFATLLPSCSCLKQNKEIYNAIVATVTEL
                     ATLAPVYHLKCLPDREATELCRKTVEG"
     CDS             9009..9449
                     /locus_tag="ctg80_9"
                     /transl_table=11
                     /translation="MKKSIPNEILLPEVARLIKEGHTVTITVRGNSMNPFLVDRRDRVT
                     LGDFTTEQLQPGVTVLARDLTERIVFHRIIRRNGDILILQGDGNLAQTEETDIGRVMGV
                     MTEAMRKDKRYTADGKVWKLYSYWWMKLNPARRWLLALFRRI"
     CDS             9462..9728
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: Stand_Alone_Lasso_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg80_10"
                     /sec_met_domain="Stand_Alone_Lasso_RRE (E-value: 9.5e-14,
                     bitscore: 41.0, seeds: 25, tool: rule-based-clusters)"
                     /sec_met_domain="PF05402 (E-value: 4.5e-16, bitscore: 48.7,
                     seeds: 461, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKIKQGFILHRIGDDYIIMQDGSSNVDFSKVISLNQTSAMLWQEI
                     ENKEFDTDSVTEALTSRYDVDNESARRDAQKFIDSLDREGIIE"
     CDS             9737..10900
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NTP_transf_5"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg80_11"
                     /sec_met_domain="NTP_transf_5 (E-value: 2.1e-46, bitscore:
                     148.0, seeds: 77, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQHAFFSLVRSGLWGTPADRQLFRSVSPDDWETVYRMANSQALLA
                     LTFDGISSLPAELRPPRVLYLKWAARTAQIEQANKRLNQLLPELNTLYREAGLHPVLLK
                     GQGIGTNYRTPLHRQCGDIDIYLGKQGQPIANRLLLQQGAIVEGEASDKHASYSLKGVH
                     IENHRIILRLNSPLANRYFQQIIRKWYPQETDYALFSETGKEDSKAVSIAIPPATFNAL
                     YIFLHAFVHFLNSGIGLRQLCDWTCLLANRHKEIDATTLLRQLQDLGLLHAAQAFGYIA
                     VTRLGLPANRLPFPLEGTKQIGEQLLEDILSTGNFGQHDNRIKPRPKGYWAGKWYTFCR
                     ATRRCNELRQFAPYEALWYPVTLIGGTIAIQINRSKGVKDKKARTKK"
     CDS             10923..12023
                     /gene_functions="transport (smcogs) SMCOG1288:ABC
                     transporter related protein (Score: 99.8; E-value:
                     2.6e-30)"
                     /gene_kind="transport"
                     /locus_tag="ctg80_12"
                     /transl_table=11
                     /translation="MKKQQKDKKVKKDRREKLRYIREVSAEQRGRILLSCLTGILGVAF
                     ALAFIYATKRVIDTATGITDDNLTHIAVLTVVLLTAQLLCGAADTWISTRMQIETGNAL
                     RHRLFSRLLQSRWNELERFHTGDVVNRVEQDTTAIVTLLTSSVPAFIVTSIQLLAAFLF
                     FYFLDPSLPWLIVAILPVFLSGSRFYMRRMKRYTHDIRNSDGRIQSVIQESLQHRIVIK
                     TLEQGERHLDKLDDLQDMLHSQVMGRTRFSLSAHMLVALAFSGGYLTAFLWGAVHLSAG
                     CITFGTMTAFLQLVGKVQRPVFDLSRLIPSVVNALTAIDRLLELERLPAEADGDSIFLA
                     STPELELKDVTFRYTPDDRPVFSRPH"
ORIGIN
        1 cgactgaata ttaactttag ccattatgct gcttaatttt gattagttac ttatattcta
       61 ttattcacaa ctttacctta tttaacagag ataagttgag cgtaatattg attttaactg
      121 ttacctctgt catttataca ttattatccc ccatttttgc gtcttaaaat ctccaacatg
      181 aatatatccg aattcaatat aaatgacgag ttcattgcct gcaatcatat cacaaccaat
      241 gaactgaatc cgctagtgga aaagccatac cacaccaagg ccagtatctt cgctctatgc
      301 accaaaggag ttctgaaaac tatcataaac catactcaat tcagggttga agctaacgcc
      361 ctcctagtta ttcctcccga gaccttcgta caattgctac acacgtcaga cgatgctgaa
      421 atatatgtcg tcatattttc ccaacaactt atccagagtt caggggccgg caaggtcatg
      481 atggataagt ttcacattat aggcaaacac tatatttttc ctctatcgag aacggacttc
      541 cagctttatg ccgagttcat gacctatttg tcacacctct accaaagaac agaaagcccc
      601 tcaagtctag tttcattgca aactctactg acctatctgt tacaaggtat atccgaactc
      661 tgtccggaac gccctagaat aaaagagact ccgggcagca ggcatttcaa ccaataccgc
      721 atttttatcc gattggtaca cacagactat gtccgggagc atcaagtgtc ctattatgca
      781 ttgaaaatga atatgagacc ggcagctctt tgccgccttg tcaaaaagga atcaggatat
      841 acagccatgg aaatcatcaa caatactatc atcatggatg ccaaagcaca actttgtacc
      901 gccaacactc cgataaagga tatagccgtg agtctaggtt ttaataatgc ggccttcttc
      961 aacaaattct ttaaacgtca tacgggaata cctcctcaga agttccgtac atcctcaaaa
     1021 caataaaatc tactcaaaac ccaaaatgcg gatattctgt cctgagaata cccgcattcc
     1081 tcaataagag aagtccgtca tcagcctacc ttcttggcaa taaagaacac ataaccgtaa
     1141 aattccttat acttgccgta cagttcatcc tcaatcattt ggagtaagct gaactcttcg
     1201 gcaattttat taccggcata tttcttacgg aaaatctcct gagccgcaac ctttgaagca
     1261 aagtaatgct ctgtccagca attctccggc aaaatgaatg tagcaacggg aagataacct
     1321 gccttgtaca acttggtcac ctgattggga agtgtatcca tttcagaata ggcgtccatc
     1381 cagaagtcat tgatttccgc aggacgttcg tccgtaaacc atgaactctc ggatacggca
     1441 atataccctc ccggtttcag atatttacgc cactccttca agccacgttc aaagccgatg
     1501 ttatagatag caccttcaca ccaaatcata tccagctcct cctcaccgaa agggagggca
     1561 tccattgaac cgacaattcc ttttactctg tcctgcaagc ccaactgcct tgcattacgg
     1621 ttgaagatgt caataaagcc ggggaaaagg tcaattccgg taatctgtcc cggaacatgg
     1681 ccagccaata ccattgtctg accacccgtt ccacaaccga tatcggcaat aagggattca
     1741 tcggtaagac cgtctacaaa gctcaatgcc ttcaacgtca cttcaggact gccagggcct
     1801 tgccgttcca tattggagaa aaagtcacag attaaattaa attcgaaatc gtggatagtt
     1861 ttattttcgt tactcatttt cttactatat tttgcatata cggaaagtat cacaacacct
     1921 tcagcataat atgcggatta aacttgaatt ataacaatag aaaaacactc tcgaaagaag
     1981 ttatccgaaa gtaaacgaaa ggggacaatc tgtgcatgga acacagattg tttacaaaac
     2041 caaatccgat ttaaatgtct ttgtcatact gcaaagataa gcaatatttt atttaatcaa
     2101 agattttacg gttaataaag attttccctt gcaccgggcg catgctgaag aaccgcacct
     2161 accacctggc aagtatccag ttccttacag tcgccacaag tattgaaacc tttttcgtac
     2221 acacatttgc ggatagcaca ataatcgctg caataggtaa acttcacccc gtctgcacgg
     2281 caccccatac aatggatggt ttccgccgta atttccggcg tattgttcag cacactccac
     2341 tctttggcgg ttttctctct cagctcatcg tcattattga cagtggctat acgggcggcg
     2401 caattttcgc aatccagtcc gcaacatgca attaattgtt tcatcacttg gttataacca
     2461 tttatgtgtt tctcatagca agcatttgtc tacctcctct ttatctgaat ttaagaggag
     2521 gcagacagcc atgctacaaa tatacggtta ttattgtgtg aatgccaaat taattttcca
     2581 tcactttgct tccacacttc cacccacctc ctgcatcccc ctgtccatcg gcatttgccc
     2641 tgcgatggaa gcaacctgaa aaggtggaag caaaatttgc ttccacctgc ctgaaacgcc
     2701 tgagttttgc agtaagctgc tatcccctag cataatactg catgcagatt acatgaatcg
     2761 gcaggttcgg ttttcctgca ttttcgggct tgtccttact gtgaagtcaa cggatatgga
     2821 gttggactgt aggagcatag taggagttat cgggaatcaa aggccgacta tgaataatgc
     2881 actctaatgt cttttacacc gttgtataat acgtttgcgc cttgtgcgca ataggttcgg
     2941 gctacgtact tcatctgtaa tagctctgga gttagtgacg cctaacggcc atgaacaact
     3001 ctgcttacgg tcgtcaaacg attgctttat ggtcgaaagc agggttgttc atggccgtta
     3061 ggcgtcataa attccctatg ccacagcaga caaacaaagg gagaagagta aaggaatacc
     3121 tatgttttag ataaaaatcc acaagctttc actcgtgctc tccataggtt atgagagcag
     3181 gcttcgcgct ctgtgcgata aattcccatt tatcagcagg catactcact tacgaaactt
     3241 caattactta tataaattgt ttcagccaaa ggcagtacgg acatttgcaa aaatatggaa
     3301 agtcttatta tgaaaaattg ctatggcatc gacttccgtt cgtggcataa ggagctacgt
     3361 acacgcgaga aaaccaagca gccaccctgc aaactgccgg acagagcaag ccggagtttg
     3421 cagggtgttc tgtttaaagt atatcaaatc tctgttttaa ttttgcttaa aaagatttta
     3481 ttcagcttct tttcggtctg tcttcccctc tttattcgcc acatagccgc tatgctcctc
     3541 agaaaaacat cctcaaagac aatgcagaca gttactaaat atttgaagga gttatcggga
     3601 gttagaagtg ataactctcc taactcctat aaatgaaaga gacgtgagcc tttcccaaaa
     3661 aaaatagaga aacatagata cacttaaaca aaaaacaatt atctttgtca caaatccgct
     3721 atagcgtagt gggtttattt acatattagt aagagcatta ttgaaattat cttctttatt
     3781 caaacttcgc aactttgaaa atttccctga agataacaac aaggatgctc acgtctatgt
     3841 ttatatggtt ttctcccatc aggggggata gtatatacac aaacgacgtg agtgactgtt
     3901 gtatatccag ggaaagggca atgcgaaggc ctgaataaag gatatacaaa catagttact
     3961 cacgtttttt ttattgttta acctttaaat aatttgtgta tatgaaacag aacacaccag
     4021 acggtagaga agcatacatc actccgtcta tcgaagttat caaaatggag aatgaaggag
     4081 tcattgcaac aagcggcgaa ccttaccatc ccattacgcg ctcctattcg ggcagcacct
     4141 ctacccatag ctacaattcg gcatccagca gcgacttgga agacctaatc aatgacatct
     4201 taaccgtaga aaactaaggg ggacttcatt atgatgaaat taagaaacct tatgcaagtt
     4261 gcctgcatgg caactgctgc cttgaccgca ttcagttgca gccaagagga atttgaaaac
     4321 agcgggtgga aaggaaacat caccgttaac gcaacgtttg aaggcgcagg taccgacacc
     4381 cgtactaccg taaacgatga atacaagatt ctatggcaag ataccgatgc cctagggttg
     4441 ttctgtagta atgcagaaag taattatagc aatacaaaat tagaatatgc aagcggtgct
     4501 ggtcaaactt ccgccacttt caacggcagc aagccaagcg gagaaacggc tgtattctcc
     4561 atctatcctt accaacaaaa catgagcgta agcggcaata cattgaccat gactctacct
     4621 gccacgctta caaattataa cggcagcagc aatggcccga tgtatgccaa ggtgacaaat
     4681 cccgacaatc tgagcgctct gtccttcaag cacatggcag ccatgataaa actgaccgtc
     4741 aacaagattc cggcagaggc cactactttc aagattattg cctccaataa cattgcaggt
     4801 acttgtacgg tagacttaac cgcagcagac ccgatactga cggtagcaag caatggaagc
     4861 aaggaaatca ctgcctcctt cactgcttca aacgatataa aatcgcgcaa cttctacatt
     4921 cctttgccca caggtactta tagttccatc actgcccaac tgacgaatgg aagcgacaag
     4981 gtatatttta ccaagacgct taatgacaaa atcttaggga gaagagacat attggtagta
     5041 cctcctttgg attgcgttgt tgtagatgct acaaccccca gtgcgcttag tacagcttta
     5101 gctgattcaa aaaatctccc acaagaagca ccgacagcag caaccgtaac cgacattgca
     5161 gtcagcggca gcttcaatac cacttctggc agcaacgacg gcatcgccat cccggtttta
     5221 cagaactcgg acatcaacct gacgttcaat acagccccaa cgaccagtac tgccgctccg
     5281 ttgacgctga ccgacaagac caataccagc gtaagtgctc ccgccgccac tgccaccaac
     5341 agtgtatcct tggctgtacc ggaaaccaca gcagagcaag aagctccttc tgtagccatc
     5401 accatgccaa gcaccaccgt tacattggca gcagtaggca ataaagccac ttacaatgaa
     5461 gtgactgcca ctaccgccca gcagacattg attatcaatg caggcgtcac cgtaaagaag
     5521 ctgactgtaa aaggcggtaa cttgaagata tatggaaagg tagaacaatt ggtacacgat
     5581 gccggcgata ccacaatcta tataataaaa ggaactgaag catcacttcc ggcaacaatc
     5641 gacagcaaat ttgtagttca atccgacgtg gcagtcctaa agaccgcttt cgccaacggc
     5701 gaagatttta aattgtccgc cgatgccgac atcacagggc aaagcgtcag tgtacccgcc
     5761 ggaaagtccg tggttcttga cttgaacgga tatacactga ctgccgacaa cagcgcaaca
     5821 ggcaaaatca tcgtcttggg caagatgaca ctgaaggaca gctctaccga gaagaaaggc
     5881 aagatagttg ccagccagga ttatacagcg gcttcttata atggcagtct gattgaaata
     5941 gccggtgaag atgcctccat gaccatggaa agcggcaaca tcagtgcagt cagagagact
     6001 ccggacagta acggccaata tggcgtcgga gtgacggacg gtggagactt caccatgaca
     6061 ggcggcaaga tagaagccgg atggtttgca gtggcaggca acggcaatta caagacgcag
     6121 aactccatca tcaacatcac agacggagaa ctcatttcta ctgctgacta tgcagtctat
     6181 ctgccccaat ccggcacaac gaccatcagt ggcggcaagg tttatggtgc cgcaggaggt
     6241 gtatgcatcc aacgaggcac tctgaatgtg gaaggtacag ccttgattac cagtaaaggc
     6301 acaggtagca ccggcaactg gggcgacggt accggaggac tggactgcgc cgccatcaac
     6361 gtaagtggag catatggcat tgccacagta aacatcaaag gcggtacact gattgccgaa
     6421 gcaaagtcac tcatcacaga aggcaccact tatacaccgg tcatcaacgt taccggcggt
     6481 acattctccg acccaagcgc gctgaagtac atgaaggcaa atgcaaatgt gaacataaag
     6541 ttgaccgccg acaagacctg cccgggattc aagaccacaa gcggacaaac cttgacgatg
     6601 gacttaggcg gcaagattct tacacttgct gacccgaccg taggttccac cggcaccgaa
     6661 acgaacagct gtcaattact cgaaggttca aacgttactt tcaagaacgg aacgctgaag
     6721 agtgacaaca acaaaatcat gattcagaac tactgcaacc tgacattaga taatatgaca
     6781 gtagaagaca caaatgccca atacgtagta agcaacaatt gtggcaacat aagcatcaac
     6841 aataccacta tcaacgcagg aagcaatgcg aatcaatttg cattcgacgt atgcggctat
     6901 gcaaagtaca ctgctggagt cacggttacg gtaagcggta cgagcgtcat caatggaaaa
     6961 gtggaaattt ccaagagtgc aggaaatacc gaacttatga agctgaatat cacaagcggt
     7021 actttcaacg gtgacttaaa ggtagatgca tccgtgagaa ccgaaaatgc ccaaagtatc
     7081 atctctgttt ccggaggtac attctccgac ccaagcgtac tgaagtacat ggcaaccaac
     7141 gcaactgtgg atataaaact tctctcaaat atcaacatcg ccaagacgaa gcttgccaca
     7201 ggctacatat tgaatgctgc aaacgcaacg gcaaacttaa acctgaatgg ccacgacatc
     7261 atcaattcct cagaaacagc tgatgccact cctttcacac aaatctttac tgtacagaac
     7321 ggaacactaa acatttcagg caacggcaat gtgaagtgcg atgcatctgc tacagcgaaa
     7381 gacgatggtt atcgcatggt aattgaagcc cgaggatacg ggacagtaaa tattcatggt
     7441 ggttcttact ataacaccca gaaactgaac acccagatag acctgattta tgcaagagag
     7501 aatgggaaaa tcaatatcta tggaggaaca tttgaatccg gcaaatatgg tacacccaac
     7561 aacgacacgg atggcagata ctgggtactg aacttaaaga atacagacaa gaacactgcc
     7621 agcatccagg tgtccggtgg aacgttcatc aatttcaacc cggcaaatcc gaatatggac
     7681 gacaatgagt cctatttggt aacaggctac gaggttaccc gtgacggcag tgtatataca
     7741 gcagcccaca aagtcggtga tgggaggaaa gaatatattg ttggccaaac aagtcaggag
     7801 aaccgataag ccaaattcta agaaaggaag caatatatcc tcgcaaacca aacgaagaga
     7861 tatcggaatc gccttattac tatcttttag atgcggcgga cagcggattt tcttttatag
     7921 atctgcgtcc tccgcgtcta aagaatgaca acaagacagt tgaaaaatct ctcaaatctt
     7981 cctcattcac acaaacattc attatttttc tgagtagccc aaagtatcat gaataacaac
     8041 taacaatcaa aacatatgag aatacagata ttggattatc aagtaggacc gcacaccttt
     8101 cgcatggtga aaccttccga cttcaatata ttcaaggcgc tgccttcact gattccgttc
     8161 atcacgacaa tagacacgac gcaaaaagta atctttgaaa cagagataga cgatgacgaa
     8221 acaacgacaa aacgaaccat agcgaaaact cccgatgata tatgtttcaa ctgggaagat
     8281 gccgattgca tcattcgccc tttgccccac agctcacacc ttgtatccat caccccacgg
     8341 aaaagcggga aaaactattg gatggagtgc aacgataact tcaggcaatg cttcatccac
     8401 ctaccggcct gcaggacaga aacaccggct ccggaaaacg aaacgaactt cgtactgaac
     8461 aacttcttga tgatgctcta tgccttcaat gccgcccgcc accatacact gctgatgcat
     8521 gcctcggttg tcgctactga aacaggcaaa ggctacctct tcttagggaa aagcggcacg
     8581 ggcaaaagta cgcacaccgg gctctggctg caacagttct cggactgcca tctactgaac
     8641 gatgacaatc cgatagtaca tgtggacagc ctcggcaagc aagccactgt tttcggttct
     8701 ccgtggagcg gaaagacacc ttgctatcgg aaagaatcca tgaccgtagg cgccttcgtc
     8761 cgcttggaac aagcaccgca gaatgaaata gagcaagaga gagcagcaca tgctttcgcc
     8821 accctcctcc cctcctgctc ttgcctaaag cagaacaagg aaatctataa cgccattgtc
     8881 gccactgtga cggaacttgc cacgctggca cccgtctatc atctgaaatg cctacccgac
     8941 cgtgaagcga cggaactttg cagaaagacg gtagaaggat aagttatgaa tgatgaactg
     9001 aacagccgat gaagaaaagc attcccaacg agatattgct tcccgaagtg gcgcgtctca
     9061 tcaaagaggg acatacagta accatcaccg tgcggggcaa cagcatgaat cctttcttag
     9121 tggaccgccg tgaccgggtg acactgggcg atttcaccac agaacagctg caaccgggcg
     9181 tcaccgtact ggcacgcgac ctgacggaac gcatcgtctt tcaccgcatc atccgtcgga
     9241 acggagacat actcatcctg caaggcgacg gcaacctcgc ccagaccgaa gaaaccgaca
     9301 tcggacgggt aatgggcgtc atgaccgaag ccatgcgaaa agacaaacgg tacaccgccg
     9361 acggcaaagt ctggaagctc tactcctact ggtggatgaa gctaaacccc gctcgccgct
     9421 ggctgctcgc cctgttcaga agaatataaa acaaaataac catgaaaatc aaacaaggat
     9481 ttatcctgca ccggataggc gatgactaca tcatcatgca agacggctcg tcgaacgtgg
     9541 acttcagcaa agtcatcagc ctgaaccaaa cttccgccat gctttggcaa gagatagaaa
     9601 acaaagagtt cgatacagac agcgtgacag aagccctgac cagccgctat gatgtagata
     9661 acgaatcggc ccgtcgcgat gcgcagaagt ttatcgactc ccttgaccgc gaaggaatca
     9721 tagaataagg acggatatgc aacacgcttt cttttcattg gtacgctccg gcctgtgggg
     9781 cactccggca gaccgacaac tcttccggtc ggtctcgccg gacgactggg aaaccgtgta
     9841 ccgcatggca aactcacaag ccctgcttgc actgactttt gacggcataa gcagtctgcc
     9901 ggccgaactg cgccctccac gcgtcctcta tctgaaatgg gctgcccgga ctgcacagat
     9961 agaacaagcc aacaaacgcc tcaaccagct tctgcccgaa ctcaataccc tttaccggga
    10021 agccgggctg catcccgtac tgctgaaagg gcaaggcatc ggcaccaact accgcactcc
    10081 cttgcaccgg caatgcggag acatcgacat ctatttagga aaacaagggc aacccatagc
    10141 caaccgcctc ctgctgcaac aaggcgccat agtcgaggga gaagcgtccg acaagcatgc
    10201 tagctacagt ttgaaaggag tacacatcga gaaccaccgc atcatcctcc ggctgaacag
    10261 tccgcttgcc aaccggtact ttcagcagat tatcagaaaa tggtacccgc aggaaacaga
    10321 ctatgcccta ttctccgaaa ccgggaaaga ggactcgaag gccgtcagta tcgccatacc
    10381 tccggccacc ttcaatgcac tttatatctt cctgcatgcc tttgtacatt tcctgaacag
    10441 cggaatcggc ctgcgccagc tatgcgactg gacttgtctg cttgccaatc gccacaaaga
    10501 aatagatgcc accaccctgc ttcgccagtt gcaggacctc ggactattgc atgccgcaca
    10561 agcattcggc tacattgccg tcacccgact gggattgccc gccaaccggc ttcctttccc
    10621 cttggaaggc accaagcaga taggagaaca attattggaa gacatcctgt ctaccggtaa
    10681 cttcgggcaa catgataacc gcatcaagcc acgccccaaa ggatattggg caggaaagtg
    10741 gtacaccttc tgccgcgcca cccgacgctg caacgaactg cgtcaatttg caccgtacga
    10801 agcactctgg tatcccgtga ctctgatagg gggaacgata gctatacaaa taaaccgatc
    10861 aaaaggagta aaagacaaga aagcaaggac aaagaaataa aagaacccgg aaaataaaag
    10921 gaatgaaaaa gcaacagaag gacaaaaaag tgaaaaagga cagacgtgaa aaacttaggt
    10981 atattcgaga ggtatctgcc gaacaacgcg gacgtatcct gctaagttgc ctcaccggca
    11041 ttctgggcgt ggcctttgcc ctagccttta tctatgcaac caaacgggtg atagacaccg
    11101 ctaccggaat aacagacgac aacctgacgc atatcgccgt tctcaccgtt gtcctgctga
    11161 ctgcccaatt actgtgcgga gctgctgaca cttggataag tacccgtatg cagatagaga
    11221 cgggcaacgc ccttcgccac cgcctcttct cgcgcttact gcaaagccgc tggaacgaat
    11281 tggagcgttt ccataccgga gacgtagtga accgggtaga acaagacacc accgccatcg
    11341 tcacattgct cacctcttct gtcccggcat tcatcgtcac gagtatacaa ctgctggcag
    11401 cctttctatt cttctacttt ttagaccctt cactgccatg gctgattgtt gccatcctgc
    11461 ccgtctttct atcaggcagc cgtttctata tgcgacgaat gaaacgctat acacatgata
    11521 ttcggaacag tgacggtcgc atccagtccg tcatacaaga gagcctgcaa catcgcatag
    11581 tgattaaaac attggaacaa ggcgaacggc atctggacaa actcgatgac ttgcaagaca
    11641 tgctccacag ccaagtcatg ggacgtaccc gtttctcgct ttctgcccac atgttagtgg
    11701 cccttgcctt ttccggcgga tacctcacgg cttttctttg gggagccgtt cacctcagcg
    11761 caggctgtat caccttcgga acgatgaccg cctttttgca attggtagga aaagtccagc
    11821 gtcccgtgtt cgacctctca cgcctgatac cttccgtagt caatgccctt accgccatag
    11881 accggctatt ggaattggaa agactgccgg cagaagcgga tggtgacagc atattcctcg
    11941 cctctacccc ggaactggaa ctgaaagacg tgacttttcg ctacactccc gatgaccgtc
    12001 cggtattcag ccgccctcac tgaccccgcc gttcaggcgt ttatgcgcaa ggtcaccatg
    12061 cac
//
