LOCUS       c00240_gnlPro..         5402 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|IHFJBEFA_240.
ACCESSION   c00240_gnlPro..
VERSION     c00240_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-07 16:11:29
            Original ID  :: gnl|Prokka|IHFJBEFA_240
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 5402
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..5402
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[741:5401]"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      742..5401
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
     cand_cluster    1..5402
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /kind="single"
                     /product="TPP_AA_metabolism"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..5402
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="TPP_AA_metabolism"
                     /region_number="1"
                     /rules="(TPP_enzyme_C and not (PFL-like or PFL_6_pcresol or
                     PFL_9_tma or Gly_radical or Gly_430_pcre or Gly_8-9_TMA or
                     PFL_acetate1 or PFL_acetate2 or Gly_radical_scatole or
                     PFL_proline or PFL_toluene) and minimum(2, [ALS_ss_C,
                     AlaDh_PNT_C, Arginase, BKACE, BcrAD_BadFG, Beta_elim_lyase,
                     CPSase_L_D2, Cys_Met_Meta_PP, ELFV_dehydrog, GRDB,
                     Glu_syn_central, Glu_synthase, Gly_reductase, HAAA1, HG2B1,
                     HG2B2, HGD-D, HleuD1, HleuD2, HleuS1, HleuS2,
                     Homoserine_dh, ILVD_EDD, IlvC, Lactoyl-CoA1, Lactoyl-CoA2,
                     Lyase_aromatic, MAAL_C, OKR_DC_1_5_lysine,
                     OKR_DC_1_5_ornithine, OKR_DC_1_7_arginine, OKR_DC_1_C,
                     OTCace, PALP, Proline_reductase, Sacchrp_dh_C, TPL,
                     Thr_dehydrat_C, TnaA, Urocanase]) and not (POR or POR_N or
                     PFOR_II))"
                     /tool="gutsmash"
     CDS             3..680
                     /locus_tag="ctg240_1"
                     /transl_table=11
                     /translation="ARGGLERTLMEKVVSNKPAVVSLLKVQYRMHEEIMKFPSQWFYNG
                     ELEAAPEVRYRGILDWDTPIHWIDTSEMDFKEEFVGETFGRINKAEADLLLSELKIYIN
                     RIGGSRILEEKIDFGIISPYKAQVQYLRNKIKADASLKPYRSLFTVNTVDGFQGQERDV
                     IFISLVRANEEGQIGFLNDLRRMNVAITRARMKLVILGEAETLKHHGFYRKLLEFIQNI
                     GNQ"
     CDS             complement(742..1785)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: IlvC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) IlvN"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg240_2"
                     /sec_met_domain="IlvN (E-value: 2.5e-47, bitscore: 149.2,
                     seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="IlvC (E-value: 2.1e-41, bitscore: 130.3,
                     seeds: 295, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAQLNFGGVIENVMTREEFPLEKAREILKDETIAVIGYGVQGPGQ
                     ACNLRDNGFNVIVGQRPGKTYEKAVADGWVLGETLFGIEEACQKGTIVMCLLSDAAVMS
                     VWPTIKPYLTPGKALYFSHGFAITWNDRTGVVPPKDIDVIMVAPKGSGTSLRTMFLEGR
                     GLNSSYAVYQDATGKAFDKTIALGIGIGSGYLFETTFIREATSDLTGERGSLMGAIQGL
                     LLAQYEVLRENGHTPSEAFNETVEELTQSLMPLFAKNGMDWMYANCSTTAQRGALDWMT
                     PFHDAIKPVVQKLYASVKSGNEAQISIDSNSKPDYREKLNAELKALRESEMWQTAVTVR
                     KLRPENN"
     CDS             complement(1836..2588)
                     /locus_tag="ctg240_3"
                     /transl_table=11
                     /translation="MMSENNKIGTYKFVAEPFHVDFTGRLTMGVLGNHLLNCAGFHASD
                     RGFGIATLNEDNYTWVLSRLAVELDEMPYQYEDFSIQTWVENVYRLFTDRNFAIIDKEG
                     KKIGYARSVWAMISMNTRKPADLLALHSGSIVDYVCDEPCPIEKPSRIKVASKEPVAAL
                     VAKYSDIDINGHVNSIRYIEHILDLFPIEMYKEKRIRRFEMAYIAESYYGDELTLFMDD
                     AGEGVYDVEVKKNGSEVVCRSKVIFTEK"
     CDS             complement(2585..3145)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ALS_ss_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg240_4"
                     /sec_met_domain="ALS_ss_C (E-value: 3.6e-20, bitscore:
                     60.8, seeds: 685, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDKKLYTIIVHSENFAGLLNQVTAVFTRRQINIESLNVSASSIKG
                     VHKYTITAWTDKDTIEKVTKQITKKIDVLQAHYFTDDEIYQHEIALYKITTPTLEEKPE
                     VSKVIRKYNARIVEVNAVFAIVEKNGMSEEITNLYEELRQLDCVLQFVRSGRVAITTSC
                     FERVNEYLADREAKYRQSKHQES"
     CDS             complement(3178..4929)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg240_5"
                     /sec_met_domain="TPP_enzyme_C (E-value: 5.1e-48, bitscore:
                     151.4, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MADNNKKSNFSSLSQGEGRGEALITGAEALMRSLEHQGVKTIFGY
                     PGGSIMPVFDALYDHRKELNHILVRHEQGATHAVQGFARVSGEVGVCLVTSGPGATNTI
                     TGIADAMIDSTPIVVIAGQVGTNFLGTDAFQEVDLVGITQPITKWSYQIRRAEDVAWAV
                     ARAFYVAKSGRPGPVVLDFAKNAQVEKTEYAPTKVDYVRSYLPVPEMEPEAIRKAAELI
                     NGAERPLVLVGQGVELGEAQQELRAFIEKAGMPAGCTLLGLSALPTNHPLNKGMLGMHG
                     NLGPNINTNKCDVLIAVGMRFDDRVTGKLETYAKQAKIIHFDIDPAEIDKNVKTDVAVL
                     GDCKETLAAVTQLLEPANHQEWIDSFRQYEEVEEEKVIRPELHPAGKALSMGEVVRAVS
                     EATHNEAILVTDVGQNQMMSARYFKYSKERSIVTSGGLGTMGFGLPAAIGATFGRPDRT
                     VCVFMGDGGLQMNLQELGTIMEQKAPVKMILLNNNFLGNVRQWQAMFFNRRYSFTPMMN
                     PDYMKIASAYDIPARRVMTREELAKAIDEMIATDGPFLLEACVEEEGNVMPMTPPGGSV
                     NQMLLEC"
     CDS             complement(5021..5401)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ILVD_EDD"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg240_6"
                     /sec_met_domain="ILVD_EDD (E-value: 1.5e-53, bitscore:
                     170.8, seeds: 918, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VITHEGPKGGPGMQEMLYPTSYIKSRHLGKECALITDGRFSGGTS
                     GLSIGHVSPEAAAGGNIGKIKDGDIIEIDIPNRSINVKLTDEELAARLMTPVTRNREVS
                     KALKAYASMVSSADKGAVRLID"
ORIGIN
        1 ccgcccgtgg aggtctggaa cgaacattga tggagaaagt ggtgtccaac aaacctgccg
       61 ttgtctcttt gctgaaagtg caataccgca tgcacgagga aatcatgaaa tttccttccc
      121 aatggtttta taatggcgag ttggaagccg ctcccgaagt gcgttaccgg ggcatcctgg
      181 actgggatac ccctatccac tggattgaca cctccgaaat ggatttcaaa gaagaatttg
      241 tgggagagac tttcggacgc atcaataaag cggaagcgga cctgctccta tcagaactga
      301 aaatctacat caaccgtatc ggtggcagcc gcattctgga agaaaaaata gacttcggca
      361 tcatctcccc ttacaaggca caagtgcaat atctccgcaa caagataaag gcagacgctt
      421 cactcaagcc ttatcgcagc ttgttcactg taaatacggt ggatggcttc caagggcaag
      481 agcgcgatgt tatcttcatc agccttgtcc gcgccaacga agaagggcag ataggattcc
      541 tgaatgattt aaggagaatg aatgtagcca tcacccgggc acgtatgaag ctggtgatat
      601 tgggagaggc agagacgctg aaacatcacg gtttttaccg gaagctattg gagtttattc
      661 aaaatatagg gaatcaataa taaagaaata ccccctccgg taacaccgaa gagggtattt
      721 cacctattta tataaagctg attaattgtt ttccggacga agtttacgaa ctgtaacagc
      781 tgtctgccac atttcgcttt cacgcaaggc tttcaattct gcattcagct tctcacgata
      841 atcgggtttg gagttgctgt cgatagaaat ctgagcttcg ttacccgact tcacgcttgc
      901 atacaatttc tgtacaaccg gcttgatggc atcatggaac ggggtcatcc aatccagcgc
      961 accacgctgt gccgtagtag aacagttggc atacatccag tccataccat tcttggcaaa
     1021 caatggcatc aaagattgag tcaactcttc cacagtttca ttgaatgctt cagaaggagt
     1081 gtgaccgttt tcgcgcaata cttcatactg agccaacagc aatccctgga tagcacccat
     1141 caatgaaccg cgttcaccgg tcaagtcgga agtggcttcg cggatgaaag ttgtctcgaa
     1201 caaatatccc gaaccgatac cgatacccag tgcaatcgtc ttgtcaaaag ccttacccgt
     1261 agcatcctga tagacggcat atgatgagtt caagccacgc ccttcgagga acatggtacg
     1321 aagtgaagta ccggaacctt tgggagcaac cataataaca tcaatatctt taggaggaac
     1381 cacgccggta cggtcgttcc aggtaatagc aaaaccatga gagaagtaaa gagcctttcc
     1441 gggagtcaaa taaggtttga tagtcggcca tacagacatt acagctgcgt cagacaacag
     1501 acacatgacg atagtacctt tctgacaagc ctcttcgatg ccgaacaaag tctcacccag
     1561 tacccatccg tcagccacag ccttttcgta tgtcttaccc ggacgttgtc ctacaatcac
     1621 attgaaaccg ttatcacgca agttgcaagc ctggcccggg ccttgtacgc cataaccgat
     1681 tactgcaatt gtttcatctt tcaaaatctc acgtgctttt tccaaaggaa attcttcgcg
     1741 ggtcattaca ttctcaataa caccgccaaa attcaattgt gccatttttt gttttaattt
     1801 ttatttgtgg cttacgccaa cgttgataaa tttatttatt tctctgtaaa tatcacttta
     1861 gagcgacaga ccacttcgct gccattcttt ttcacctcca catcgtaaac gccctcaccg
     1921 gcatcatcca tgaacaaagt caactcatcc ccataatagc tttcggctat atatgccatt
     1981 tcaaaacgac ggatgcgctt ctccttatac atctctatcg ggaacaaatc aaggatatgc
     2041 tcgatgtaac ggatgctgtt cacatgcccg ttaatgtcaa tatcactgta tttggctacc
     2101 aaagcagcaa ccggttcctt tgaggccacc tttatccgcg aaggtttttc tatcgggcaa
     2161 ggctcatcgc aaacataatc tacaatgctg ccactatgaa gagccagcaa atctgccggc
     2221 ttacgggtat tcatgctaat catcgcccaa acggaacgtg catacccaat cttcttaccc
     2281 tccttatcga tgatagcgaa attacggtct gtaaaaaggc gatagacatt ctccacccaa
     2341 gtctgaatgg agaaatcttc gtactgataa ggcatttcat ccagttcgac agccagacgg
     2401 gacaataccc aagtataatt gtcctcgttt agagtcgcga tgccaaaacc gcggtcgctg
     2461 gcatggaaac ccgcacaatt caacaaatgg ttgcccaata ctcccattgt cagccgtccg
     2521 gtaaagtcga catgaaacgg ttcggcaaca aacttgtagg tacctatctt attgttctcg
     2581 ctcatcatga ttcctggtgt ttactttgac gatattttgc ttcacggtcc gccagatatt
     2641 cattgacacg ctcaaagcag ctggtcgtaa tggctacgcg acccgaacgg acgaactgaa
     2701 gtacgcaatc caactggcgc aactcctcat aaagattggt tatttcctca ctcatgccat
     2761 tcttctcaac aatggcaaat acagcattca cctccacaat acgggcattg tacttacgga
     2821 ttactttgga cacctccggt ttttcttcca gcgtaggggt cgttatttta taaagggcaa
     2881 tctcgtgctg atagatttca tcatccgtga aataatgggc ttgcagcaca tctattttct
     2941 tggtaatctg cttggtcacc ttttcaatgg tatccttgtc cgtccaagcg gtaatggtat
     3001 atttatgtac ccccttgatg gaggaggccg atacattcaa actctcgatg tttatctgcc
     3061 ggcgggtaaa cacagccgtc acctgattca gcaaaccggc aaagttttcc gaatgaacaa
     3121 tgattgtata tagtttttta tccatagata gagtaagttc tttaatttcg catgacttca
     3181 gcattccaac aacatctgat tgaccgaacc gcccggaggt gtcatcggca ttacatttcc
     3241 ttcttcctcc acacaagctt cgagcaggaa cggtccgtca gtcgctatca tctcgtcaat
     3301 cgcttttgcc agctcctcgc gggtcattac cctgcgtgca ggaatatcat atgccgaagc
     3361 aatcttcata taatccggat tcatcatcgg agtaaacgaa taacgacgat tgaagaacat
     3421 cgcctgccat tgacgaacat tgcccaggaa gttattgttc aacagaatca tcttcaccgg
     3481 agccttttgt tccatgatgg tacccagttc ctgcaggttc atctgcaagc cgccgtctcc
     3541 catgaatacg cataccgtgc ggtccggacg tccaaaagtg gcaccgatag ctgccggaag
     3601 gccgaagccc atagtaccca ggccaccgga agtaacaatg ctacgttcct tgctgtattt
     3661 gaaataacgg gcggacatca tctgattctg gccgacatca gtcaccaata tcgcctcgtt
     3721 atgggtagcc tcactcacag cacgcaccac ctcacccatg cttagcgctt ttcctgccgg
     3781 atgtaattcc ggacggatta ccttttcctc ttccacttcc tcgtattgcc ggaaactgtc
     3841 aatccattcc tgatggttgg cgggttccag caattgggta acggcagcca gtgtctcttt
     3901 gcaatctccc aggacagcaa catcggtctt tacattctta tctatttcgg cagggtcaat
     3961 atcaaagtgg ataatcttcg cctgcttggc atatgtttcc aatttacccg tcacacggtc
     4021 atcaaagcgc atgcctacgg cgataaggac atcacattta ttggtattga tattgggccc
     4081 caggttaccg tgcataccaa gcattccttt gttcaacgga tggttcgtag gtaatgcgga
     4141 aagtcccaat aaagtgcatc cggcaggcat tccggctttc tcaatgaaag cacgaagctc
     4201 ttgctgggct tctcccagct ccacgccttg tcctaccagc accaaaggcc gttccgcacc
     4261 atttattaat tcagcagcct tccgtatggc ctccggctcc atttcgggaa cgggaagata
     4321 gctacggaca tagtccacct tagtaggcgc atattctgtt ttctccactt gggcgttttt
     4381 agcaaaatcc agcacgaccg gtcccggacg tccgctcttt gccacataga aagcacgtgc
     4441 cactgcccag gccacatctt ctgcacgacg aatctggtaa ctccatttcg tgataggctg
     4501 agtaatgcct accaagtcca cttcctgaaa tgcatccgta cccaagaagt tcgtccctac
     4561 ctggccggca atgacaacga taggcgtact gtcaatcatg gcatctgcaa tgcccgtgat
     4621 agtattggta gcacccggtc cactggtaac cagacaaacg ccaacctcgc ctgatacacg
     4681 tgcaaagcct tgtaccgcat gggttgctcc ttgttcatgg cgaaccaaga tgtggttcaa
     4741 ttccttccgg tggtcgtata aggcatcgaa taccggcatg atgctccctc ccggataacc
     4801 gaaaatagtc tttactccct gatgctccag agagcgcatc aatgcttctg cgcctgttat
     4861 tagagcctca ccccgaccct ctccttggga gagggaggaa aagttactct ttttattatt
     4921 atcagccata ctttatctat tcattatatt taaaagctca atagtagctt gaaaaatttg
     4981 tttcattctc tcctcccctc gctttcggaa aggggggctt ttaatcaatc agcctcacag
     5041 cccctttgtc agcggaactc accatactgg catatgcttt caatgctttg gagacttcac
     5101 ggttgcgggt taccggagtc ataaggcgtg ctgcaagctc ttcatccgtc aacttcacat
     5161 tgatagaacg gttcggtata tcaatttcga taatgtcccc atccttaatc ttgccgatat
     5221 taccaccggc agccgcttcg ggagaaacat gtccgatact tagtccggaa gtaccaccac
     5281 tgaaacgccc gtcggtaatc aatgcacact ccttacccag atggcgggat ttgatataag
     5341 aagtaggata aagcatctct tgcatacccg gtccaccttt cggcccttcg tgagtgatga
     5401 cg
//
