LOCUS       gnlProkkaGOLEIIAB_207   5023 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|GOLEIIAB_207.
ACCESSION   gnlProkkaGOLEIIAB_207
VERSION     gnlProkkaGOLEIIAB_207
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-12-02 05:52:43
            Original ID  :: gnl|Prokka|GOLEIIAB_207
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 5023
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..5023
                     /aStool="rule-based-clusters"
                     /category="PKS"
                     /contig_edge="True"
                     /core_location="[545:1775]"
                     /cutoff="20000"
                     /detection_rule="(APE_KS1 or APE_KS2)"
                     /neighbourhood="20000"
                     /product="arylpolyene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      546..1775
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(APE_KS1 or APE_KS2)"
                     /neighbourhood="20000"
                     /product="arylpolyene"
                     /protocluster_number="1"
     cand_cluster    1..5023
                     /SMILES=""
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(APE_KS1 or APE_KS2)"
                     /kind="single"
                     /product="arylpolyene"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..5023
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="arylpolyene"
                     /region_number="1"
                     /rules="(APE_KS1 or APE_KS2)"
                     /tool="antismash"
     CDS             2..538
                     /NRPS_PKS="Domain: PKS_KR (16-107). E-value: 1.2e-09.
                     Score: 30.2. Matches aSDomain:
                     nrpspksdomains_ctg207_1_PKS_KR.1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001:short-chain dehydrogenase/reductase SDR (Score:
                     158.4; E-value: 3.7e-48)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg207_1"
                     /transl_table=11
                     /translation="MTHAALNGWMEKHPDTYIEVLVNNAGIRRDNLMLWMEQDEWSRVL
                     DISLNGFFNVTQPLLKNMLVKRFGRIINIVSLSGIKGMPGQTNYSAAKGGMIAATKALA
                     QEVARKHVTVNAVAPGFIRTDMTNGIDENEWKKQIPAGRFGEPGEVAALVGFLASEQAS
                     YITGEVISINGGIYT"
     aSDomain        50..322
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg207_1_PKS_KR.1"
                     /evalue="1.20E-09"
                     /label="ctg207_1_PKS_KR.1"
                     /locus_tag="ctg207_1"
                     /protein_end="107"
                     /protein_start="16"
                     /score="30.2"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C2"
                     /tool="antismash"
                     /translation="YIEVLVNNAGIRRDNLMLWMEQDEWSRVLDISLNGFFNVTQPLLK
                     NMLVKRFGRIINIVSLSGIKGMPGQTNYSAAKGGMIAATKALAQEV"
     CDS_motif       227..277
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg207_1_0001"
                     /evalue="2.40E-05"
                     /label="PKSI-KR_m4"
                     /locus_tag="ctg207_1"
                     /protein_end="92"
                     /protein_start="75"
                     /score="16.8"
                     /tool="antismash"
                     /translation="SLSGIKGMPGQTNYSAA"
     CDS             546..1775
                     /NRPS_PKS="Domain: PKS_KS(Iterative-KS) (77-405). E-value:
                     1.1e-50. Score: 164.6. Matches aSDomain:
                     nrpspksdomains_ctg207_2_PKS_KS.1"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     arylpolyene: APE_KS1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1022:Beta-ketoacyl synthase (Score: 308.5; E-value:
                     1.3e-93)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg207_2"
                     /sec_met_domain="APE_KS1 (E-value: 1.8e-171, bitscore:
                     559.4, seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRRVVITGMGIYSCIGKNQDEVKDSLFQGRSGIGIDPARKEMGYF
                     SALTGLVERPDLKKLLDRKKRHSLAEQGEYAYMATLEAFRQAQIDEEFLLDHEVGILYG
                     NDSSAAPVIEAIDVIRAKKNTAMVGSGSIFQSMNSTITMNLSVIFHLKGINFTISGACA
                     SGSHAIGMAYLLIKSGLQDCILCGGAQEVNPYSVGSFDGLGAFSTREDEPEKASRPFDK
                     GRDGLVPSGGGASLVLESYESAVRRGATILAEVIGYGFSSNGDHISVPNVDGPRRSLQM
                     AINDAGIPLEEIQYINAHATSTPVGDLNEAKAIAEVFGNHRPYVTSTKSQTGHEMWMAG
                     ASEVIYSILMMNNGFIAPNLNFEEPDEASALLNIPSRRIETEFDTFLSNSFGFGGTNSS
                     LIIRKFKENN"
     aSDomain        777..1760
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg207_2_PKS_KS.1"
                     /domain_subtypes="Iterative-KS"
                     /evalue="1.10E-50"
                     /label="ctg207_2_PKS_KS.1"
                     /locus_tag="ctg207_2"
                     /protein_end="405"
                     /protein_start="77"
                     /score="164.6"
                     /tool="antismash"
                     /translation="MATLEAFRQAQIDEEFLLDHEVGILYGNDSSAAPVIEAIDVIRAK
                     KNTAMVGSGSIFQSMNSTITMNLSVIFHLKGINFTISGACASGSHAIGMAYLLIKSGLQ
                     DCILCGGAQEVNPYSVGSFDGLGAFSTREDEPEKASRPFDKGRDGLVPSGGGASLVLES
                     YESAVRRGATILAEVIGYGFSSNGDHISVPNVDGPRRSLQMAINDAGIPLEEIQYINAH
                     ATSTPVGDLNEAKAIAEVFGNHRPYVTSTKSQTGHEMWMAGASEVIYSILMMNNGFIAP
                     NLNFEEPDEASALLNIPSRRIETEFDTFLSNSFGFGGTNSSLIIRKF"
     CDS             1797..2048
                     /NRPS_PKS="Domain: PP-binding (7-74). E-value: 4.3e-14.
                     Score: 44.7. Matches aSDomain:
                     nrpspksdomains_ctg207_3_PP-binding.1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg207_3"
                     /sec_met_domain="PP-binding (E-value: 6.1e-15, bitscore:
                     44.7, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTNEEIIEKIRTTLAEEFEIDVEQIQPDAPLMQTLELDSLDLVDM
                     VVLIDKNFGFTVTAKDFAGIKTFQDFYNLVISHMQKED"
     aSDomain        1818..2018
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg207_3_PP-binding.1"
                     /evalue="4.30E-14"
                     /label="ctg207_3_PP-binding.1"
                     /locus_tag="ctg207_3"
                     /protein_end="74"
                     /protein_start="7"
                     /score="44.7"
                     /tool="antismash"
                     /translation="EKIRTTLAEEFEIDVEQIQPDAPLMQTLELDSLDLVDMVVLIDKN
                     FGFTVTAKDFAGIKTFQDFYNL"
     CDS             2048..2932
                     /locus_tag="ctg207_4"
                     /transl_table=11
                     /translation="MSETWKGKTRGGIFGYMFFIYMIRCLGITAAYGFLALVVLYFIPF
                     APKATGNTWSYARNRLKYGRLKSVALLLKNYYRLGQILIDKVAIGNGMTGKYHFKFENY
                     QAFLDVLNGNTGVIMIGAHVGNWEIGAPFFDEYGKKINIVMFDAEHERIKEILEKNAST
                     RDYKIIPVNEDSLTHVFRITEALDRREYVCFQGDRYLNKEKLLTTSFMGKEAKFPMGPF
                     LLASKLKVPVVFYFAMREAQRTYRFHFFIAETVVRTKEKRAEQALLEQYTQTLEKIVRQ
                     YPEQWFNYYPFWT"
     CDS             2946..4016
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1042:O-methyltransferase (Score: 117.8; E-value:
                     1e-35)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg207_5"
                     /transl_table=11
                     /translation="MMHKRYTKEQCTAAEAQRLAQEIAFGPVVFQVSRLMLKFGIFQLL
                     SGKREGYTLQEISGQTGLTRYAAQVLLEASLTIGTILLEEDRYVLAKAGWFLLNDKMAR
                     VNMEFNHDVNYQGLFHLEEALLNGRPEGLKVFGEWPTIYEGLSQLPEQVQKSWFGFDHF
                     YSDQSFGKALEIVFSHHPKRLLDIGGNTGRWATQCVQYNKEVEVTIVDLPQQLEMMRKQ
                     TAGLSGSERIHGHGANLLDRDVPFPTGFDAVWMSQFLDCFSEEEVISILTRVAQSIGKD
                     SKVYIMETLWDRQRYETASYCLTQISLYFTAMANGNSKMFHSDDLIRCIENAGLEVEEI
                     QDNIGLGHSILQCRLK"
     CDS             4013..4450
                     /locus_tag="ctg207_6"
                     /transl_table=11
                     /translation="MSSKEIICQGEELFRLIPQRPPMVMIDRFYGIEENTSWSGLTVTP
                     DNLFCRDGVLQETGIIEHIAQSAAARVGYIYMLRKEPVPLGFIGSVEKMKLFRLPSAGA
                     ELYTGITIVQEVFDITLITAEVKENDELLAECRMKIYLKKE"
     CDS             4447..4890
                     /locus_tag="ctg207_7"
                     /transl_table=11
                     /translation="MKRKTSPHQAALTDRTTIKVRFSEIDSMQIVWHGEYVRYFEDGRE
                     AFGKRYGLDYMSIYREGYVVPIVDLTCQFKQPLSFGEEAIVETRYIHSDAAKILFEYTI
                     YRASDQNIVATGTTTQVFLNTNRELELVNPAFYIEWKKKWNII"
     CDS             4875..5021
                     /locus_tag="ctg207_8"
                     /transl_table=11
                     /translation="MEHHLTTYITHDTLISALGFGTQENLEAIRSYHSGITLQTDKRIA
                     DTPL"
ORIGIN
        1 agccacacac gccgcactga acggctggat ggagaagcat cccgatacct acattgaggt
       61 actggtgaac aatgccggta tacgccgtga taacctgatg ctgtggatgg aacaggatga
      121 atggagccgg gtgttggata tcagcctgaa cggtttcttt aacgtcaccc aacccttgct
      181 gaaaaatatg ctggtaaagc gattcggacg tatcatcaac atcgtttccc tgtcgggtat
      241 caaaggaatg ccgggacaaa ccaactattc ggcagccaaa ggcggaatga tagccgccac
      301 caaagcactg gcacaggaag tggccagaaa acacgtgacg gtgaacgccg tagcaccggg
      361 atttatccgc acggatatga ccaacggcat tgatgaaaat gaatggaaaa aacagatacc
      421 ggcaggacgg ttcggcgaac ccggagaagt agccgcactg gtaggcttcc tggcatcgga
      481 acaagcctcc tatatcaccg gagaagtaat ttccatcaat ggaggaatct atacataagc
      541 agaagatgag aagagtagtg attacaggca tgggtattta ttcgtgcata ggcaagaacc
      601 aagatgaggt gaaagactct ttgttccaag ggcgttccgg catcggcatc gatccggcac
      661 gtaaagagat ggggtatttt tccgcattga caggacttgt cgaacgtcct gatttaaaga
      721 agttattgga ccgcaaaaag agacatagcc tcgccgaaca gggagaatat gcctatatgg
      781 ctaccttgga ggcattccgt caggcacaaa tagacgagga gtttttattg gatcatgaag
      841 taggcatatt gtatggaaat gacagtagcg ccgctccggt aatcgaggcc attgatgtca
      901 ttcgtgccaa gaagaatacg gctatggtgg gctccggttc tatcttccag tccatgaact
      961 ctacgattac catgaacctt tcggttattt tccatttgaa gggaattaat tttaccatat
     1021 cgggagcttg tgccagcggt tcacacgcca tcggcatggc gtatcttctt attaaatcag
     1081 gacttcagga ttgcattctg tgcggagggg cacaagaggt aaatccttac tccgtgggta
     1141 gtttcgacgg attgggcgcg ttctccaccc gtgaggacga accggaaaag gcatcgcgcc
     1201 cctttgacaa gggacgggac ggtttggtac ccagcggagg aggcgccagc ctggtactcg
     1261 aaagttatga atcagccgta aggcgcggag ctactattct ggcagaagtc ataggatacg
     1321 gtttttcatc caacggagat catatttccg taccgaatgt ggacggtccc agacgctctt
     1381 tacagatggc aatcaacgat gcgggcattc ccttggaaga aatccaatat atcaatgcac
     1441 acgccacttc cacccccgtg ggagatttga atgaggcaaa agccatagcg gaagtgtttg
     1501 gaaaccatcg gccctatgtc acatccacca agtcacaaac cggacatgag atgtggatgg
     1561 caggcgccag tgaagtcatt tattccatct tgatgatgaa taacggattt atcgctccta
     1621 atctcaattt tgaagaaccc gatgaagcct ctgctctgct gaacatcccc tcccggagga
     1681 tagaaacgga atttgacacc ttcttgtcca actcattcgg attcggagga accaattcct
     1741 cactgattat ccgtaaattt aaagaaaaca attaattcaa accaatatat aaatttatga
     1801 ccaacgaaga aatcatcgaa aagatcagaa ccaccctggc cgaagaattt gagattgatg
     1861 tagaacagat ccaaccggac gcacccttga tgcaaacctt ggaattggat agccttgacc
     1921 tggtggatat ggtagtactg attgacaaga atttcggttt caccgttaca gccaaagatt
     1981 ttgccggtat caaaaccttc caggatttct ataatctggt aatttcacat atgcaaaaag
     2041 aagactgatg tccgaaacat ggaaaggtaa gacaagagga ggcatattcg gatacatgtt
     2101 ctttatctac atgatccgct gtctggggat aactgcggcc tacggcttcc tggcattggt
     2161 cgtcctctac ttcatacctt tcgcaccgaa agcaacgggc aatacttgga gttacgcacg
     2221 gaacaggctg aaatacggac ggctgaaatc cgtcgcactg ctcctgaaaa actattaccg
     2281 gctgggacaa atattgattg acaaagtggc catcggcaac ggaatgaccg gcaagtatca
     2341 tttcaagttt gagaactatc aggcattttt agacgtacta aacggaaaca ccggagtaat
     2401 tatgattggc gcccatgtgg gcaactggga aataggcgct cctttcttcg atgaatatgg
     2461 caaaaagatc aatatcgtca tgtttgacgc cgaacacgaa cggataaagg agattttgga
     2521 aaagaacgcc tctacgcgag actacaaaat aattccggtg aatgaagaca gcctgacaca
     2581 tgtattccgc atcacggaag cgctggaccg ccgggagtat gtctgctttc agggagaccg
     2641 ctatctgaat aaagagaaat tactcacgac ttctttcatg ggaaaagaag ccaaatttcc
     2701 gatgggccct ttcctgctgg cttcgaagtt aaaagtaccc gtcgtattct attttgccat
     2761 gcgtgaagcc caaagaacgt atcgtttcca tttctttata gccgagacag tagtacggac
     2821 gaaagagaaa cgggccgaac aggcattatt ggagcaatat acacaaacgc tggaaaagat
     2881 tgtccggcag tatccggaac aatggttcaa ttactacccg ttctggacat aaaaataaat
     2941 ctggtatgat gcataaaaga tatacaaaag aacaatgtac ggctgccgaa gcgcaaagac
     3001 tggcacaaga gatagctttc ggtcctgtgg tattccaagt atcgcgcctg atgttgaaat
     3061 tcggaatttt ccaattattg tccggcaaac gggaaggata tacgctgcaa gaaatcagcg
     3121 ggcagaccgg actgacacgc tatgcggcac aagtattact ggaagcatcg ctgaccatcg
     3181 gaaccatcct gttggaagaa gaccgttatg tactggccaa ggcaggctgg tttctgctga
     3241 acgataaaat ggctcgtgtc aatatggaat tcaatcacga tgtgaactat caaggcttgt
     3301 tccatttgga agaagctctt ttaaacgggc gtccggaagg attgaaagta ttcggagaat
     3361 ggcctaccat ttacgaaggt ctgtcccaat tgccggaaca ggtacagaaa agctggttcg
     3421 gctttgatca tttctattcg gaccagtcat tcggcaaagc gttggaaatc gtgttcagcc
     3481 atcacccgaa acgcttgctc gatattggcg ggaataccgg cagatgggcc acacaatgcg
     3541 tacaatataa taaggaagtg gaagtaacca tcgtggacct gcctcaacaa ctggaaatga
     3601 tgagaaagca aacggccggt ttgtccggta gtgaacgcat acacggtcac ggcgccaatc
     3661 tgctggatcg ggacgtgccc tttcccacgg gttttgacgc tgtatggatg agccagtttc
     3721 tggactgctt ctcggaagaa gaagtcatca gcatcctgac ccgtgtggca caatccatcg
     3781 gcaaagacag caaagtctat attatggaaa cattatggga tcgccaacgg tatgaaacag
     3841 catcttattg cctgacacaa atcagcctct actttacagc aatggccaac ggcaacagta
     3901 agatgttcca ttcggatgac ctgatccgct gcattgaaaa tgccggattg gaagtggaag
     3961 aaattcaaga taacatagga ctgggacaca gtatcctgca atgcagactg aaatgagcag
     4021 caaagaaatc atctgtcagg gagaagagct gttccggctg attccccaac gcccgcccat
     4081 ggtaatgata gaccgcttct atgggataga agaaaataca tcctggtcag ggctgaccgt
     4141 cactcccgac aacctgttct gccgggacgg tgtattacag gagacgggaa tcatagagca
     4201 tatcgcccag tcggcggcgg cacgtgtagg ttatatctat atgctgcgga aagaacctgt
     4261 accattaggt tttatcggtt cggtagaaaa gatgaaacta ttccgtcttc cttctgccgg
     4321 agcggaacta tataccggta taaccatcgt tcaggaagta tttgatatca ccctgattac
     4381 cgccgaggta aaagaaaacg atgaattgct ggccgaatgc cggatgaaaa tatatctgaa
     4441 gaaagaatga aacgaaaaac aagtccacat caggcggcac tgacggaccg gaccaccatc
     4501 aaagtccgct tcagtgagat agattccatg cagatagtat ggcatggaga atatgtgcgt
     4561 tatttcgaag acggacgcga agctttcgga aagcggtacg gtctggacta tatgagcatc
     4621 taccgggaag gatatgtagt tcctatcgta gacctgacct gccaattcaa acaaccgctg
     4681 tcttttggcg aggaagcgat tgtcgagaca cggtatattc atagtgatgc tgccaaaatc
     4741 ctttttgaat acaccatcta ccgggcatcg gaccaaaaca ttgtggcaac aggaaccact
     4801 acacaggtat tcctgaatac aaatagagaa ctggaactgg ttaatcctgc cttttacata
     4861 gagtggaaaa agaaatggaa catcatctga ctacctatat cacccatgat accctgatca
     4921 gcgcgctggg tttcggcaca caggaaaatc tggaagccat ccggagctat cacagcggta
     4981 tcaccctgca gacggacaaa cggattgcgg acactcccct att
//
