LOCUS       c00115_gnlPro..         9341 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|IFJEMNEF_115.
ACCESSION   c00115_gnlPro..
VERSION     c00115_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-05 13:04:43
            Original ID  :: gnl|Prokka|IFJEMNEF_115
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 9341
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             complement(1..723)
                     /locus_tag="ctg115_1"
                     /transl_table=11
                     /translation="MEKNKVGEFHFVTESYLTDFRGRITIPMIGTYLLHAASCHAADRG
                     FGYNDMTERHTAWVLSRLAIEMTSYPAMSESVTLYTWVDEVGKLFTSRCFELVNGEGKT
                     FGFARSIWAAIDMETRRPTLLDVEGLSAYITDRPCPIEKPGKIAPVENNTSGEPYRVKY
                     SDLDVNGHLNSIKYMEHLLDLFDISLFREKEISRFEIAYQSEGKYGMELTLHNQEVSLD
                     KYNMAICNDGKAISRAAVT"
     protocluster    1..9341
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[759:4889]"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      760..4889
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
     cand_cluster    1..9341
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /kind="single"
                     /product="TPP_AA_metabolism"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..9341
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="TPP_AA_metabolism"
                     /region_number="1"
                     /rules="(TPP_enzyme_C and not (PFL-like or PFL_6_pcresol or
                     PFL_9_tma or Gly_radical or Gly_430_pcre or Gly_8-9_TMA or
                     PFL_acetate1 or PFL_acetate2 or Gly_radical_scatole or
                     PFL_proline or PFL_toluene) and minimum(2, [ALS_ss_C,
                     AlaDh_PNT_C, Arginase, BKACE, BcrAD_BadFG, Beta_elim_lyase,
                     CPSase_L_D2, Cys_Met_Meta_PP, ELFV_dehydrog, GRDB,
                     Glu_syn_central, Glu_synthase, Gly_reductase, HAAA1, HG2B1,
                     HG2B2, HGD-D, HleuD1, HleuD2, HleuS1, HleuS2,
                     Homoserine_dh, ILVD_EDD, IlvC, Lactoyl-CoA1, Lactoyl-CoA2,
                     Lyase_aromatic, MAAL_C, OKR_DC_1_5_lysine,
                     OKR_DC_1_5_ornithine, OKR_DC_1_7_arginine, OKR_DC_1_C,
                     OTCace, PALP, Proline_reductase, Sacchrp_dh_C, TPL,
                     Thr_dehydrat_C, TnaA, Urocanase]) and not (POR or POR_N or
                     PFOR_II))"
                     /tool="gutsmash"
     CDS             complement(760..1314)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ALS_ss_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg115_2"
                     /sec_met_domain="ALS_ss_C (E-value: 9e-19, bitscore: 56.7,
                     seeds: 685, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNTKQLYTVIIFSENTVGLLNQITVIFTRRQLNIETLSVSPSAIK
                     GIHKFTITTFADEDTIDKVVKQIDKRVDILKAYYNTDEDLVYQEIALYKLSTELFIKMG
                     TVEDLIRKYNARILEMNEDCVVLEKSGHYDETQALFKELSETIGVLQFIRSGRVAITKS
                     KVERLSDMLSAMEKKLQEKHV"
     CDS             complement(1327..3027)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg115_3"
                     /sec_met_domain="TPP_enzyme_C (E-value: 2.7e-51, bitscore:
                     162.5, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDKQKITGSEALLKALIAEGVDTIFGYPGGQAIPIYDSLYDYRDQ
                     LKHILVRHEQGATHAAQGYARVSGKVGVTVVTSGPGATNTITGIADALMDSTPMVVIAG
                     QVPSPLLGTDAFQEVDVIGITQPITKWAYQIRRPEEIAWAVSRAFYIASTGRPGPVVLD
                     LAKDAQVGLVDYEYQKVDYVRSYQPEPDIREERIEAAASLINNAKKPFCLVGQGVILGG
                     AEEELKEFLLKNDIPAGSTVLGLSALPSDFPLNKGMLGMHGNVGPNRKTNECDVLIAIG
                     MRFDDRVTGDLKTYAKQAKIIHLDIDNSEIGKNVPVDVKVLGNAKHTIPMITALLEERK
                     RPEWNAEFEPDEKEEYNKVIEKELYPTEGQLKMGEVVRKVSEATDNDAILVTDVGQNQM
                     MGVRYFKYKQTRSVVTSGGLGTMGFGLPAAIGAKLGAPDRTVCFFTGDGGIQMTIQELG
                     TIMQENLNVKIIVLNNNFLGMVRQWQELFFNERYSNTIMKNPDFVAIAKAFGIASRAVD
                     KREDLDEAIAEMLNHDGAYMLVANVETCGMVYPMVPAGGSVTNMILGDK"
     CDS             complement(3054..4889)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ILVD_EDD"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg115_4"
                     /sec_met_domain="ILVD_EDD (E-value: 2.1e-218, bitscore:
                     715.1, seeds: 918, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MMKNPLRSSYSTEGRRMAGARALWRANGMKEEQFGKPIIAIVNSF
                     TQFVPGHVHLHEIGQQVKAEIEKLGCFAAEFNTIAIDDGIAMGHDGMLYSLPSRDIIAD
                     SVEYMVNAHKADAMVCISNCDKITPGMLMASMRLNIPTIFVSGGPMEAGNLDGRALDLI
                     DAMIEAADDSISDEQVEKVERSACPTCGCCSGMFTANSMNCLNEAIGLALPGNGTVVAT
                     HANRTRLFKKAAKMIVDNAFKYYRDGDDSVLPRSIATRQAFLNAMSLDIAMGGSTNTVL
                     HLLAVAHEAEVDFTMKDIDMLSRKTPVICKVAPSCSYHVEDVNRAGGIIGIMNELVKAG
                     LVDGSVKRADGLTLNEAIDQYCITSVNVTEEAINIYKSAPAHRFNLVLGSQESYYKELD
                     TDRATGCIRDVEHAYVKDGGLAVLYGNIAQDGCVVKTAGVDESIFRFAGPAKVFDSQDA
                     ACEGILKDQVVSGDVVVITYEGPKGGPGMQEMLYPTSYIKSKHLGKECALITDGRFSGG
                     TSGLSIGHISPEAAAGGAIGLVKDGDIIEINIPERTIHVKVTDEELAKRREAEEARGTK
                     AFTPPFRQRTVSKALKAYAKMVASADKGGVRIVED"
     CDS             complement(5207..6754)
                     /locus_tag="ctg115_5"
                     /transl_table=11
                     /translation="MAALYPIGIQNFEKIRKEGYLYVDKTALIYQMVKTGSYYFLSRPR
                     RFGKSLLVSTLEAYFQGKEELFEGLAMEKLEQDWLEYPILHLDLNAERYSEASSLDSIL
                     QRHLNLWEDTWGKDEREKTLSDRFIGVIRRAKARSGRRVVILVDEYDKPLLQAIGDELL
                     QDEYRSILKPFYGVLKTMDGDIRFALLTGVTKFGKVSVFSDLNNLMDISMDDRYVEICG
                     MTETEIHAYMEQGVLDLTRNLQMDYEEVCMELKRRYDGYHFTHRSQGMYNPFSLLNTFA
                     KSDFGDYWFETGTPSYLVELLKHTDYDLYNMAHTETNADVLNSIDAVSRNPIPVIYQSG
                     YLTIKSYNPRFKIYTLGFPNQEVEEGFLNYLLPYYTSVNVIDTSFQLFKFIKEIESGDV
                     DAFLSRLQSFFADTPYELIRNLEVHYQNVLFIVFKLVGFYVKVEYRTSRGRIDLVLQTD
                     HYIYIMEFKLDGTTEEAMRQIEEKQYALPFASDERKLFKIGVNFDNETRNIAGWSVD"
     CDS             complement(6830..7426)
                     /locus_tag="ctg115_6"
                     /transl_table=11
                     /translation="VVVVCNVLVAGCASGKVFDRVEKIPHRKVGLLLGTAPVTPWGTKN
                     LYFTYRIDAAVKLFHAKKVDYFIVSGDNHSTDYDEPTCMRDSLVACGVPDERIISDYVG
                     FRTLDLEVRCKAIFGQDSVTVISQSFHNERAIYLAGHNQIDAIAFNAQDVTSVWTTWLR
                     GHSRELLARVKIFIDLIIGKQPRFWGEKVKIPEIR"
     CDS             complement(7948..9156)
                     /locus_tag="ctg115_7"
                     /transl_table=11
                     /translation="MEKLDDMKLTVLYIEYRNFFIDVLSRFYGFEKYDIYHYSEILNVD
                     ELCRNEALNWDMYLIEFWGKEKINWEYLSGNKCLSWTADLFDKYYDYWEWDILSSNEGI
                     FWNELLLNKYKSKLNWNLLSLNKSLPWSIDFINRYVDRLNWVNLSANLSLPWSDYLLEY
                     YENLWDWNLISANPSLPWTDDLIIKYMDRLNWAGLSMNPALPWSSEFIQKYKYNWIWGY
                     SSDWVMTDDIGLCGNSGIHWNEELIEMFDGFIDWGELSLNTGDMWNECLIDKYLCKLHW
                     EECWCPPLGMGGLSSNPSLPWSLDFVDKYKPYLNIKEICSNMSFPWREEDFRNNNGGII
                     NDCDKSYWKLLSMNEGLPWSVGVLYDNRCWFDWNLMKGNVKVYDNCLSVLEKEKMKFLL
                     ELV"
     CDS             9256..9339
                     /locus_tag="ctg115_8"
                     /transl_table=11
                     /translation="MYCTDLEETQWQVIKKILNLQERKRKYR"
ORIGIN
        1 ggtaacggca gcgcggctga tggctttgcc gtcgttacag attgccatat tatatttatc
       61 gagggatact tcctggttat ggagagtcag ctccatccca tactttcctt cggactgata
      121 agctatttcg aaacggctta tctctttttc tcggaacaga ctgatatcga acaagtcgag
      181 caggtgttcc atgtatttga tactgttcag gtggccgttt acgtccaggt cactatactt
      241 cacacggtaa ggttcgccgg aagtgttgtt ttccaccgga gcaattttac ccggtttttc
      301 aatcggacag ggacggtcgg tgatataagc actcaggccc tccacatcga gcaaggtcgg
      361 gcggcgggtt tccatatcga tagccgccca gatagagcgg gcaaagccaa aggtcttgcc
      421 ttcgccgttc accagttcaa agcaacggct ggtaaacaac ttaccgacct catccaccca
      481 ggtatataaa gttacggatt cagacatggc aggataagaa gtcatctcga tagccagacg
      541 ggaaagaacc caggcggtat gcctttcggt catatcgtta tatccgaatc cacggtcggc
      601 ggcatggcaa gaagcagcat gcaacaaata agttccgatc atagggattg taatacgtcc
      661 ccggaagtcc gtcagataag actctgttac gaaatgaaat tctcctactt tgttcttctc
      721 cataatttac tttatttaca aaatgtttcc ttattattct cagacatgtt tttcctgcaa
      781 cttcttttcc attgcagata acatgtcgct cagacgttct accttactct tcgttatagc
      841 aacgcgtccg gaacggataa attgcaggac accgatcgtc tcactcaatt ctttaaacaa
      901 agcctgtgtc tcatcataat gaccactctt ttccaacacc acacaatcct cattcatttc
      961 aaggatacgg gcattgtact tacggatcag atcctcaacc gtccccatct tgataaagag
     1021 ttcggtactc agtttataaa gagcgatttc ctggtaaacc aggtcttcat ccgtattata
     1081 ataggctttc aggatatcca cacgcttgtc gatctgtttt acgaccttgt cgatcgtatc
     1141 ctcgtcggca aaggtagtaa ttgtaaactt atgtattccc tttatagcag agggagaaac
     1201 agaaagcgtc tcaatgttca gttgccggcg cgtaaagata acagttatct gattcagaag
     1261 accaacagtg ttttccgaaa agataataac ggtatataat tgttttgtat tcatagtttc
     1321 tcctccttac ttatcaccca aaatcatgtt tgtcacgctt cctccggccg gaaccatcgg
     1381 atataccata ccacaagttt ccacattggc aaccaacata taggcaccat cgtgattcaa
     1441 catttcagca atcgcctcat ccaagtcttc ccgtttatct accgcacggg aagcaatacc
     1501 aaaagccttg gctatcgcta caaaatccgg attcttcatg atggtattcg aataccgttc
     1561 gttgaagaac agctcctgcc actggcgtac cattcccagg aaattgttgt taagaacgat
     1621 gatctttaca ttcagatttt cctgcatgat agttcccaac tcctggatag tcatctggat
     1681 accaccgtcg ccggtaaaga aacagaccgt acggtcaggc gctcccagct tcgctccaat
     1741 ggcggcggga aggccaaagc ccatcgttcc caaacctcct gaagtaacta cgctgcgtgt
     1801 ttgtttatat ttgaaatagc gaacacccat catctggttc tgacctacat ccgtaaccag
     1861 aatcgcatca ttatcggttg cttcggaaac cttacggact acttcgccca ttttcagttg
     1921 gccttcggta ggatagagtt ctttttctat taccttatta tattcctctt tttcatccgg
     1981 ttcgaattca gcattccatt ccggacgctt ccgttcttcc agtaaagccg taatcatcgg
     2041 aatcgtatgc ttggcatttc ccagcacttt cacgtcgacc ggcacattct ttccgatctc
     2101 cgaattgtcg atatccaggt ggataatctt tgcctgcttg gcataagtct tcaggtcgcc
     2161 ggttacgcga tcatcgaaac gcataccgat agcaatcagc acgtcacatt cgtttgtctt
     2221 gcggttcggt ccgacatttc catgcatccc caacatacct ttatttaatg ggaagtccga
     2281 aggtaatgca gacaagccca atacggtaga accggctggt atatcgtttt tcaacaagaa
     2341 ttctttcagt tcttcttcag ctcctcccag gataaccccc tgccctacca gacagaatgg
     2401 ctttttggca ttatttatca atgaagcagc cgcctcgata cgttcctccc tgatatccgg
     2461 ttcaggttgg taactacgaa cataatccac tttctgatac tcataatcta ccaaacccac
     2521 ctgtgcatct ttcgccaaat ccagtaccac aggtcccggg cgaccggtcg atgcgatata
     2581 gaaagcacgg gaaacggccc aagcaatttc ttccgggcgg cgtatctggt aagcccattt
     2641 ggtaatcggt tgtgtgatac cgatcacatc aacttcctgg aaagcatctg ttccaagcag
     2701 cggagacgga acctggccgg caatcaccac catcggtgta ctgtccatca gcgcatcggc
     2761 aataccagtg atggtattgg ttgccccggg acccgaagta accaccgtta ctcccacttt
     2821 tccggaaaca cgggcatatc cctgtgcagc atgtgttgca ccttgttcgt ggcgcaccag
     2881 aatatgtttt aactgatctc tgtaatcgta taaactatcg taaattggta tcgcctgccc
     2941 acccggataa ccgaagatag tatctactcc ttcagcgatc agcgctttca gcaaagcttc
     3001 cgaaccggtt atcttttgtt tgtccatctc taaaatatag tatttggtgt ttattaatct
     3061 tctactattc gtacaccgcc cttatcggcc gaagcaacca tctttgcata tgctttcagt
     3121 gctttcgata ccgtacgttg gcggaaagga ggtgtaaagg cttttgttcc gcgggcttct
     3181 tccgcttcac ggcgtttggc cagttcttcg tctgtcacct ttacatgtat ggttctttcg
     3241 ggaatattaa tttcgataat atcgccgtct ttcactaagc caatcgctcc gcctgcagcc
     3301 gcttcgggag aaatatgtcc gattgacaaa cccgatgttc caccgctgaa gcgtccgtct
     3361 gtgattaacg cacattcttt acccagatgt ttactcttta tataagaggt aggatacaac
     3421 atttcctgca tacccggacc acccttagga ccttcatagg tgataacgac gacatcgccg
     3481 gagacgactt gatctttcag gataccttcg caagcggcat cctgcgaatc gaatactttg
     3541 gcagggccgg caaaacggaa gatactttca tctaccccgg ctgttttaac cacacaaccg
     3601 tcctgtgcaa tatttccata cagaacagcc agaccgccgt ctttcacata agcatgttcc
     3661 acatcgcgga tacatccggt tgcacggtcg gtatccagtt ctttataata actttcctgc
     3721 gatccgagca ccagattgaa acggtgggcc ggagcacttt tataaatatt gattgcttct
     3781 tccgttacat ttacagaggt aatgcagtat tggtcgatag cctcattcaa agtcagacca
     3841 tccgcacgtt tcacggaacc gtccaccaga ccggctttta ccagctcatt cataataccg
     3901 ataatacctc cggcacggtt cacatcttcc acatgataag aacaactcgg agccacttta
     3961 cagataaccg gtgttttgcg tgaaagcata tcgatgtctt tcattgtaaa atcgacttcc
     4021 gcttcatgag ccacggccaa caggtgaagg actgtattcg tcgatccccc catggcaata
     4081 tccagcgaca tagcattcag aaaggcctga cgggtggcaa tactgcgagg caatacggaa
     4141 tcatcgccgt cacgataata tttaaaggca ttatcaacaa tcatcttcgc ggcttttttg
     4201 aacaggcggg tacggttggc atgtgttgca acaactgttc cgttgccggg aagagccaat
     4261 ccaatcgctt cgttcagaca gttcatagag ttagccgtga acataccaga acagcaaccg
     4321 caggtcgggc aagcggaacg ttccaccttt tctacttgtt catcgctgat agaatcgtca
     4381 gccgcttcaa tcatggcgtc gatcaaatcg agtgcacgtc cgtccagatt accggcttcc
     4441 atcggaccgc cggatacaaa gattgtcgga atattcagac gcatactggc catcagcata
     4501 cccggagtaa tcttgtcgca gttactgata caaaccattg catcagcctt atgcgcattc
     4561 accatatatt ccacactgtc agcaatgatg tcgcgggaag gcagagaata aagcattccg
     4621 tcgtgtccca tagcaatacc gtcatcaata gcgatcgtat taaattctgc ggcaaagcaa
     4681 ccgagctttt cgatttccgc ttttacctgc tgtccgatct cgtgtagatg cacatggccc
     4741 ggtacaaact gggtaaatga attcacaatg gcaatgatcg gtttaccgaa ctgttcttct
     4801 ttcatgccgt tggcacgcca taatgcacgg gctccggcca tacgtctgcc ttctgtgcta
     4861 taggagcttc ttaacggatt cttcatcata tctgttttta tcttttagtc aataaaaaag
     4921 cccttctcta tatggagaaa ggcttaagaa atatctttta cgacttcaca acttcttaca
     4981 cacctttctc cttacctact aatgactaga aggaccacca cgagaataat atgtaataca
     5041 ttgttcatca tcttttctta tcgtctttat tttgtttgac gctgcaaatg tagaataata
     5101 atttgtacga gcaaaggatt taaaagaaaa atcttacttt ttctttcatt tatcaataaa
     5161 agagggcggt tcatcttgca ttttaacagt attattaaaa tctacatcaa tcgaccgacc
     5221 aaccggctat gttccgtgtt tcattatcaa agttcacccc tatcttaaaa agtttccgtt
     5281 catccgaggc aaaaggcaag gcatactgct tctcttcgat ctgcctcatc gcctcctctg
     5341 tcgtgccatc caacttaaac tccattatat aaatgtaatg atcggtttgc aacaccaggt
     5401 caatgcgacc acgggaagta cgatattcca ccttcacata gaaaccgacc agtttgaaga
     5461 cgatgaacag gacgttctgg tagtgcactt ccagatttcg aatcaattca tatggcgtat
     5521 cggcaaaaaa actttgcaac cggctaagga aagcatccac atccccagac tcgatttctt
     5581 taatgaattt aaaaagctgg aaggaagtat caataacatt gacagaagtg taatatggaa
     5641 gcaaataatt cagaaacccc tcttctactt cctgatttgg aaagcccaat gtatatattt
     5701 taaatctagg attataggat ttgatcgtca aataaccact ttggtaaata accggtatcg
     5761 ggttacgcga aacggcatcg atactgttca acacatctgc attcgtttcc gtatgtgcca
     5821 tattgtacaa gtcatagtcg gtatgcttca acagctcgac caagtaagag ggggtacctg
     5881 tctcaaacca gtaatctcca aagtcagact tcgcaaatgt gtttaacaaa ctgaacggat
     5941 tgtacatgcc ttgcgaccta tgagtaaaat gataaccatc ataacggcgt ttcaattcca
     6001 tgcaaacttc ttcataatcc atttgcagat tacgagtcaa atccaacacc ccttgttcca
     6061 tatacgcatg gatttccgtc tcggtcatac cacaaatctc aacataacga tcatccatcg
     6121 aaatatccat caaattgttc aaatcactga acacacttac tttaccgaac tttgtcacac
     6181 ctgtcagcaa agcaaaacgg atatcaccgt ccatcgtctt caacacccca taaaacggtt
     6241 ttaatataga acggtattca tcctgcaaca gctcatcccc aatagcctgc aacaaaggtt
     6301 tgtcgtattc atccaccaaa atgaccacac gccttcccga tcgagctttt gcccggcgga
     6361 tcacccctat aaaacgatcg gacaaagtct tttcccgttc atcttttccc catgtatctt
     6421 cccacaggtt caaatgacgt tgcaaaatac tatccaagga cgaagcctcc gaatacctct
     6481 ccgcatttaa atccaaatgc aatatcggat actccaacca atcctgttcc agcttctcca
     6541 tcgccaatcc ctcgaacaac tcctccttac cctgaaaata ggcctccaaa gtcgaaacca
     6601 acaacgattt gccgaaacgg cgcggacgac tcaggaagta ataactcccg gtcttcacca
     6661 tttgataaat caacgctgtt ttatcaacat agagataccc ctccttacga atcttctcga
     6721 aattttgtat gccaatagga taaagtgcag ccataaaccg tttttatatt atctatcaag
     6781 acaaaggtaa cttatttttt atcaataagt atcttattat attacatttt catcggattt
     6841 ccggaatctt gaccttctcc ccccaaaaac ggggttgctt accaataatc aagtctataa
     6901 atattttaac ccgagccaaa agctcacgac tatgtcccct caaccaggtt gtccacacag
     6961 aagtcacatc ttgggcattg aatgcaatcg catctatttg attatgaccc gccaaataga
     7021 tcgcacgctc gttatgaaaa gactgcgaaa taacagtaac gctatcctgt ccaaaaatgg
     7081 ctttacatcg cacttccaaa tcaagcgttc gaaaaccgac ataatccgaa ataattcgct
     7141 catccggtac accacaggca actaacgaat cacgcataca agtcggctca tcataatctg
     7201 ttgaatgatt atcaccactt acaataaagt aatcaacctt ttttgcatga aacaatttga
     7261 ctgccgcatc aatacgatac gtaaaataaa gatttttcgt tccccaagga gtaaccggag
     7321 cagtccccaa caacaaaccg actttacgat gtggtatctt ttccaccctg tcaaatacct
     7381 tacctgaggc acaacctgcc accaacacgt tacaaactac aaccactatg tttatgacag
     7441 aaatgagcag aaataatggt taattgtatg attttcttct tactttgaat tacttttttt
     7501 cacagacttg ctcttttatt ataaaggatt gtcaccaaca aaataacaat cctaataaaa
     7561 caatctattt cttcttagga atatttttgt aaaaggcata tagcaaaggt attatttcca
     7621 gacatatcca aagccataag catgtcatat ttcatttgac aggaaagctt ccgtcttcac
     7681 caatcattac cggataaaac atatcatccc tgcaaagaac gattgctcca acctatcaga
     7741 gtaatataaa ttttgcagac tgtattaact aataatattt tcactgtccc caaaatacga
     7801 tgtcatattt ttcaacacac gatctttact tgtattagca tagcaataga cttttctata
     7861 aaatataggc gcatattctt ttcttcagct tcgtcactta tataactatc ctacccaatc
     7921 atccacgacc attttttgat acttcaatca aactaattca agtaaaaatt tcatcttttc
     7981 tttttctaaa acacttaaac agttatcgta tactttcaca tttcctttca ttagattcca
     8041 atcaaaccaa catctattat catatagtac tcctacagac caaggtaaac cttcattcat
     8101 actcaataat ttccagtaag atttatcaca atcatttatt attccaccat tattatttct
     8161 aaaatcctct tcacgccaag ggaaagacat attagaacaa atttctttta tatttaaata
     8221 aggtttatat ttatccacaa agtccaagct ccaaggcaat gaaggattac tactgagacc
     8281 tcccataccc aaaggaggac accagcattc ttcccaatgc aatttacata aatatttatc
     8341 aatcaaacat tcattccaca tatctcctgt atttaaacta agctctcccc aatcaataaa
     8401 accatcaaac atctctatca attcctcatt ccagtgaata cccgaattgc cacataaacc
     8461 tatatcatcg gtcattaccc aatctgatga atatccccag atccagttat atttatactt
     8521 ttgtataaac tcagaactcc aaggtaacgc tggattcata cttaatccag cccaatttaa
     8581 acgatccata tatttaatga ttaaatcatc agtccaaggc aacgatggat tggcacttat
     8641 caagttccaa tcccataaat tctcataata ttccaacaaa tagtcagacc aaggcaatga
     8701 cagattagca cttaaattaa cccaatttaa tctatcaaca tagcgattta taaaatcaat
     8761 tgaccacggt aacgatttat ttaagctcaa caaattccaa tttaacttag atttatactt
     8821 attaagcagc aactcattcc agaatattcc ctcattagaa gacaagatat cccattccca
     8881 ataatcataa tatttatcaa aaagatctgc tgtccatgac aaacacttat ttccactcaa
     8941 atattcccaa ttaatttttt ctttacccca aaattctatc agatacatat cccaatttaa
     9001 agcttcattt ctacacaatt catcaacatt caaaatttca ctataatgat atatatcata
     9061 tttttcaaaa ccataaaatc tacttaatac atcaataaaa aaatttctat attcaatata
     9121 taatacagtt aatttcatat catccaactt ttccataata attagagcct gtttaaattt
     9181 cacagtttga aataaataaa gtgtttcctc tttctgctaa aataattatt tttaattact
     9241 aagtttcaaa taattatgta ttgtacggat ttagaagaaa cacagtggca agttatcaag
     9301 aaaatcttga acttgcaaga aagaaagcga aaatacaggg c
//
