LOCUS       c00011_gnlPro..        13716 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|GLNAKHFJ_11.
ACCESSION   c00011_gnlPro..
VERSION     c00011_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-05 14:33:20
            Original ID  :: gnl|Prokka|GLNAKHFJ_11
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 13716
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..13716
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[226:3716]"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      227..3716
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
     cand_cluster    1..13716
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /kind="single"
                     /product="Fumarate2succinate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..13716
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Fumarate2succinate"
                     /region_number="1"
                     /rules="(Succ_DH_flav_C and FAD_binding_2 and (Fer2_3 or
                     Fer4_7 or SucD_FumR))"
                     /tool="gutsmash"
     CDS             complement(227..1057)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Fer2_3"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_8"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052:Succinate dehydrogenase-2Fe-2S iron-sulfur
                     cluster binding domain (Score: -1.6; E-value: 9.2)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg11_1"
                     /sec_met_domain="Fer2_3 (E-value: 2.8e-23, bitscore: 74.1,
                     seeds: 38, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_8 (E-value: 8.9e-11, bitscore: 34.2,
                     seeds: 153, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 4.8e-06, bitscore: 19.0,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LPSAATSKDSQYINTQKKDYNMAKTLNLTLKVWRQENREAKGRIE
                     TYAAKDIPVDASFLEMLDIVNEGLVKEGKEPIHFDHDCREGICGMCSLTINGIPHGPER
                     QVTTCQLHMRKFKDGDTVWIEPFRAKAFPILRDLMVDRSALDRIIAAGGYIDVRTGSAP
                     NANNIAVEKVKADAAFDAAACIGCGACVASCKNASAMLFTSAKIAHLNLLPQGQPERSK
                     RVLAMMKQMEAEGFGNCTNQYECEAACPKGISVDNIARLNRDFMRANAKEGLCF"
     CDS             complement(1035..2993)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: FAD_binding_2"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Succ_DH_flav_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1027:FAD binding domain (Score: 176.1; E-value:
                     4.1e-54)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg11_2"
                     /sec_met_domain="FAD_binding_2 (E-value: 4.3e-54, bitscore:
                     176.1, seeds: 62, tool: rule-based-clusters)"
                     /sec_met_domain="Succ_DH_flav_C (E-value: 1.2e-37,
                     bitscore: 120.8, seeds: 739, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MINFPVSDWMPDAKIPSGPIQDKWSKYKLESKLINPNNKRKYTVL
                     VVGSGLAGASAAATLAELGYNVKCFCYQDSPRRAHSIAAQGGINAAKNYQNDGDSVYRL
                     FYDTVKGGDFRAREANVYRLAEVSSNIIDQCVAQGVPFGREYGGLLDNRSFGGAQLKRT
                     FYARGQTGQQLLLGAYQALEKEVAKGHIEMFSRHEMMDLVLVDGEAKGIVTRNLVTGEI
                     KSYAGDTVLLCTGGYGNVFFLSTNAMGCNVTAAYKAYKRGAFFANPCFTQIHPTCIPVK
                     GDYQSKLTLMSESLRNSGRIWVPKSRETAEKIRKKEIKPSDVPEEERDYYLERKYPSFG
                     NLAPRDISSRAAKEACDDGRGVAITGKGVFLDFADEIKRMGREWIDGQYGNLFDMYEEI
                     TDDDPHETPMMIYPASHYTMGGLWVDYNLMSNVKGLHVLGEANFSDHGANRLGASALMQ
                     GLSDGYFVIPATLPAYLTTTKPGAVTTAAPEFKAAEDEVKERINKLLNVKGTKTVDSFH
                     RELGLIMWEDCGMARTEESLTHAIERIPQLRKEFWENVRVTGTADGINAELEKACRVAD
                     FLEFAQLLCYDALNRQESCGAHFRVEYQLPDGEAKRNDDEYAYVAAWEYTGVDSLPVLH
                     KEPLTFENVHLAIRSYK"
     CDS             complement(3015..3716)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: SucD_FumR"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg11_3"
                     /sec_met_domain="SucD_FumR (E-value: 2.6e-13, bitscore:
                     42.0, seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNALVKTICTFVTSSIGRKIIVALTGLCLVLFLAGHLAGNLLIFG
                     GPEWINTYAHGLHSMPEAALWGIRAGLAVIFIIHVWLTIQLKLENHAAREPYVFKNTIK
                     ATLSSRYMIYTGLTVLVFLIYHLYQYTLRVGYDPAQFTTFISDGTVETFDVYKMIVTGF
                     SNVWCSAFYILAVLMLFSHLRHGVQSIFQTVGVDSRKIRPFYNFIAIAYGAIICLGFIS
                     VPVSVLLGIIK"
     CDS             3917..4189
                     /locus_tag="ctg11_4"
                     /transl_table=11
                     /translation="MKRSKKEVLDADFAAARAGVLDVAAFLDRVDRGEGEADFRYHALM
                     DVLPLLSASGPGRVRAILEALSYRDDTVPETAAAKAACGAPNLSK"
     CDS             4192..5007
                     /locus_tag="ctg11_5"
                     /transl_table=11
                     /translation="MMAFIEPHIHMVCRTTDEYRAMAQAGCLAVGEPAFWAGYDRSSAD
                     GFRDYFVQLTECEPARAAKFGMDHYTWLCINPKEAQDVAFARDVMKLIPEFIDRPNVLG
                     IGEIGLNRNTSHEMTIFEEHLDLAVRLNQLVLIHTPHLEDKLKGTVMILSALKNRPDLD
                     PCRVLVDHCEEHTFPLVKEAGYWAGLTLYPTSKLNPKRAADILELYGMDRVWANSAADW
                     GDSDPLALTALACELRRRGFSRQETERLLLENPETFMGQSPKFRKVSSR"
     CDS             complement(5041..5274)
                     /locus_tag="ctg11_6"
                     /transl_table=11
                     /translation="MNLQKQQLLLRLFRYFKSRKGEPRFFNKRNICLLAAAGAYILTPD
                     EFLFDGIGRLGLLDDAAVILGAVLTVFFPDGD"
     CDS             complement(5706..6374)
                     /locus_tag="ctg11_7"
                     /transl_table=11
                     /translation="MSLSATAATALLDSSIVGYSDFASQTADFGTRKDSVSITSDDSNL
                     TLSGITFNGYGANNRDVMSVTMVLDLSKINTPETYTALFNAKNSSVSWGVGLNTDRKLQ
                     GLWNNTSYNGPVVDTPLGTEGSLTISVVTGDLGTRIYFGDSATYYSNSGLKFGNQQIDQ
                     ILMDAGLAESIEQLYIHDSLLSQEQVGQLMSEIASIPEPATASLGLLGLAALMMRRRRA
                     "
     CDS             complement(6959..7255)
                     /locus_tag="ctg11_8"
                     /transl_table=11
                     /translation="MPGAVNPPLIVTVSPSVLAVGAAVPPAAYKYVLDVSCIKSITDWL
                     TARKRYVNAASRSRGEPSREEKLNVRLIPAAVVPVLVLQPMTELSEPFSTRKP"
     CDS             complement(7666..7800)
                     /locus_tag="ctg11_9"
                     /transl_table=11
                     /translation="MYAAALQVCELQRGSLSGLKGHYVKAAVYHMDEKRAAEFDGIFR"
     CDS             complement(7912..8112)
                     /locus_tag="ctg11_10"
                     /transl_table=11
                     /translation="MTIALRTEQSSDHAETEHVTREAFWNYFVPGCHEHYLLHIMRVSP
                     SFIPELDAVAVHGSRIVGKHR"
     CDS             complement(8126..9331)
                     /locus_tag="ctg11_11"
                     /transl_table=11
                     /translation="MRGIFLVSCFLGGSALLAGCREENNSPRPATEDAARITSARQWGE
                     SRSALQKRELDRAAGPALPIPDDLPSRELVGTTRQIHQLIEASGNPARFESYTETVPVA
                     GASLRMVAIPGGTFLMGSPAEEPHRKPDEGPQHKVSISPFWISETEIPWELYTAFMENG
                     RPRAKDGQLLEEQPDDELWDSVTQPTAPYTAMNLGMGHGYEHGLPAISMSHHAASKFCE
                     WLSAQTGHYYRLPTEAEWEYACRAGSPGAYSYGNGEASLDQYAWYWNNSNDRYQKTGSK
                     KPNKWGLRDMHGNVAEWVLDSYVPDAYGKRSGLPAKDPLVIIPGAPHIVRGGSWEDDPD
                     SLRSAARRASTPAWSRQDPQNPKSIWYLTDGGMIGFRVVRPMNIPDIMTMHRLWNFSKG
                     EP"
     CDS             complement(9355..10101)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short_C2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg11_12"
                     /sec_met_domain="adh_short_C2 (E-value: 2.4e-75, bitscore:
                     245.1, seeds: 358, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQKLAGKTAIVTGAGRGIGNAVARRFASEGARVILISRSPSSCGG
                     AAEEINKEFPDSCKAYPCDVADYAAVQETMAAILKDFPQIDILVNNAGITRDSLMLRMK
                     EEDWDAVLDTNLKSAFNTVKALQRVLMKSPAGRIINMSSVIGLVGNIGQANYAASKAGL
                     IGFTKSLAQEFAPRKVTCNAIAPGFISTEMSNSIPDNLKEEIVKKIPLKEQGSVEDIAA
                     LTAFLASDDARYITGQVIACDGGMTM"
     CDS             complement(10230..10748)
                     /locus_tag="ctg11_13"
                     /transl_table=11
                     /translation="MKAFLVPLLYSALLSGASLAFGETAAGTASPAAAAPAEKIPSAES
                     LINQAFSFAINIQQTLAGVQDKESADNAVKTLQDIQKDIRHFLQLQDKLNDAEKEKEDA
                     LIEKMEKRMEMLDNRCRQEGKRLFEARYYGSAALKDILENSDEFSDLVEPDEDGTPPGA
                     LRENEEAGQ"
     CDS             complement(10812..12377)
                     /locus_tag="ctg11_14"
                     /transl_table=11
                     /translation="LFRETEMTINWGERVALVGPNGAGKSTLFRMILGEDTPDEGSISM
                     DEYAIVGYLPQEASEPKDETVLEIALGITPEMEQAIHTIRTAENANKTDTPEYAEAIDT
                     FNAANGYQLEPKAKKILKGLAFRESDFHRPAREMSGGWIMRAYLAKLLVLEPDLLMLDE
                     PTNHLDLLSLLWLQRYLKNYPGAILMISHDRDFMDELVESVYDIDNEELVEYRGNYSDF
                     LQQKDVRFEQLQAAYRNQQKEIAHIQEFIDRFRSINSKAGQVQSRIKQLEKMKIIQKPV
                     ARRKVFKFNFPQPPRSTQKVIELEKVCQSYGDRRVYENLDLLVERGERTVLVGPNGAGK
                     STLLKILAGIIPIDSGQRTPGTTTRIGYFSQARTENLNPENTVLEEIMKCSAEIREEEA
                     RSILGSFLFRRLDVEKRVSVLSGGEKSRLSLVKFLVDPPNLLLMDEPTTHLDLLSVEAL
                     VQALKHYEGTLVFISHDVHFIRSLAQKTLHVNRGTITAYAGGYDYYLEKSGILDDEKGG
                     ITAE"
     CDS             12662..13252
                     /locus_tag="ctg11_15"
                     /transl_table=11
                     /translation="MSGLANAFLALLPPDQASLPAAGAEARWLADTAVVQSAAIARDNR
                     TVLFGWLNNILVNSNLRDRGLCWQVQQDLYRDLRRRPVKYFRIGLTIRDRGTGREHSCV
                     YVNAAGKGLQGSIVLDAWKNCGHLVTLTQKDREGGKWEEDWREPFVSKAFPEGHSYGME
                     HHLVWPGWARKRPMLVQRIFQSDQQNEAKAAAE"
ORIGIN
        1 ccgtcgctgt cggacggggc ctgcttaggt ttcgtccggc atttccaagt acggtttcct
       61 ggattactgg gtgccttccg gtgtaacaat tttttacgct gcgcgacgat gaggaagcaa
      121 ctgtctggta ttttattcct ggttcaagga aacctggtaa tgaaaaaact cccgacagcc
      181 gatgccgccg ggagttttta cagagcgtct taagaaggaa tcttctttag aaacagaggc
      241 cttccttggc gttggcccgc atgaagtcgc ggttgaggcg ggcgatgttg tccacgctga
      301 tgcctttcgg gcaggcggct tcacattcat actggttcgt gcagttgcca aagccttccg
      361 cttccatctg cttcatcatg gccaggacgc gcttggaacg ttccggctgg ccctgcggca
      421 gcagattgag atgggcgatc ttggcggagg tgaacagcat ggcggaggcg tttttacagg
      481 aggccacgca ggcgccgcag ccgatgcagg cggccgcgtc aaaggcggcg tccgccttca
      541 ctttttccac ggcgatgttg ttggcgttcg gcgcggaacc ggtacgcacg tcaatatagc
      601 ctccagcggc gatgatgcgg tccagggcgg agcggtccac catcaggtcc cgcaggattg
      661 ggaaagcctt cgcgcggaag ggttcaatcc agacggtatc gccgtccttg aacttgcgca
      721 tgtgaagctg gcaagtggtc acctggcgtt ccggcccgtg gggaatgccg ttgatggtca
      781 gggagcacat gccacagatg ccttcccggc agtcgtggtc aaaatggatg ggttccttgc
      841 cttccttgac caggccttca ttgacgatgt ccagcatttc caggaaggag gcgtccaccg
      901 gaatgtcctt ggcggcatag gtctcaatgc ggcccttggc ttcccggttt tcctggcgcc
      961 agaccttgag agtgagattg agtgttttag ccatgttata atctttcttt tgagtgttaa
     1021 tgtattggct atctttactt gtagctgcgg atggcaaggt gcacgttctc gaaggtcagc
     1081 ggttccttgt ggagaacagg caggctgtcc acgccagtgt attcccaggc ggctacatag
     1141 gcgtattcat cgtcgttgcg cttagcttcg ccgtccggca gctggtattc cacgcggaag
     1201 tgggcgccgc aggattcctg gcggttcagg gcgtcatagc agagcagctg ggcgaattcc
     1261 aggaagtcgg ccacgcggca ggctttttcc agttccgcgt tgatgccgtc cgccgtgccg
     1321 gttacgcgca cgttttccca gaattccttg cggagctggg gaatgcgttc aatggcgtgg
     1381 gtcaggcttt cttccgtgcg ggccatgccg cagtcttccc acataatgag gcccagttcc
     1441 cggtggaagg agtccaccgt cttggtgccc ttcacattca ggagcttgtt gatgcgttcc
     1501 ttcacttcgt cttccgcagc cttgaattcc ggggcggcgg tggtgacggc gccgggtttg
     1561 gtggtcgtca ggtaagcggg cagcgtggcg ggaatgacga agtagccgtc agacaggccc
     1621 tgcatcaggg cggaggctcc caggcggttg gcgccgtggt cggagaagtt ggcttcaccg
     1681 aggacgtgca gccccttcac attggacatg aggttgtagt ccacccacag gccgcccatg
     1741 gtgtagtggg aggcggggta gatcatcatg ggcgtttcat gggggtcgtc gtccgtgatt
     1801 tcttcgtaca tgtcaaacag attgccgtat tggccgtcaa tccattcgcg acccatgcgc
     1861 ttgatttcat ccgcaaaatc caggaagacg cccttgccgg tgatggccac gccgcggccg
     1921 tcgtcgcagg cttccttggc ggcgcgggag gaaatgtcgc gcggggccag gttgccgaag
     1981 gagggatact tgcgttccag gtagtagtcc cgttcttctt cgggaacatc ggaaggcttg
     2041 atttcctttt tacggatttt ttctgcggtt tcacgggact tgggcaccca gatgcggccg
     2101 ctgttgcgga gggattccga catcagcgtc agtttggact ggtagtcgcc cttgaccgga
     2161 atgcaggtgg ggtggatttg cgtgaagcag gggttggcga agaaggcacc gcgcttgtag
     2221 gccttgtagg cggcagtgac gttgcagccc atcgcgttgg tggacaggaa gaacacgttg
     2281 ccgtagccgc ccgtgcagag caggacggta tcccctgcgt aggatttgat ttcgccggta
     2341 accagattgc gggtgacgat gcccttggct tcgccgtcca ccagcaccag atccatcatt
     2401 tcatggcgcg agaacatttc aatgtgtccc ttggccactt ccttttccag ggcctggtag
     2461 gcacccagca ggagctgctg gcccgtctgt ccgcgtgcgt agaaggttcg cttgagctgg
     2521 gcgccaccga aggagcggtt gtccagcagg ccgccgtatt cacggccgaa gggaacgccc
     2581 tgggccacac actggtcaat gatgttggag gagacttccg ccagacggta gacattggct
     2641 tcacgggcgc ggaagtcgcc gcctttaacg gtgtcgtaaa acaggcggta aacggagtcg
     2701 ccgtcgttct ggtagttctt ggctgcgtta atgccgccct gggccgcaat ggagtgggcg
     2761 cggcgggggc tgtcctggta gcagaagcat ttgacgttgt agccaagttc ggcaagcgtg
     2821 gcagcagcgg aggcgccagc caggccggaa cctaccacaa gcaccgtgta cttgcgcttg
     2881 ttgttcggat tgatcagttt ggactcaagc ttgtacttgg accatttgtc ctgaataggg
     2941 ccggagggaa ttttggcatc cggcatccag tcgcttacgg gaaaattaat catgactttg
     3001 agaggagttg atggttattt gatgataccc agaagaaccg agaccggcac ggagatgaag
     3061 cccaggcaga taatcgcgcc gtaggcgatg gcgataaagt tgtagaaggg ccggattttg
     3121 cgggaatcga cgcccacagt ctggaagatg gactgtaccc cgtggcgcag atggctgaac
     3181 agcatcagaa cggccaggat gtagaaggcg gagcaccata cgttggaaaa tccggtcacg
     3241 atcatcttgt acacgtcaaa ggtttccacc gtaccgtcgg aaatgaaggt ggtgaactgg
     3301 gcggggtcgt atcctacgcg cagggtgtac tggtacaggt ggtagatcag gaacaccagg
     3361 acggtcagac cggtatagat catgtagcgg gaggagagcg ttgccttgat ggtgttcttg
     3421 aacacgtagg gttcgcgggc cgcatggttt tccagcttca gctggatggt cagccagacg
     3481 tggatgatga agatcaccgc aagccccgcg cggattcccc agagggctgc ttccggcatg
     3541 gagtgcaggc cgtgggcgta ggtgttgatc cattcagggc ctccgaagat gagaaggttg
     3601 cctgccaggt gtcccgcaag gaacaagacc aaacataacc ccgtcagagc cacaatgatt
     3661 ttgcggccga tggaggatgt cacgaatgta catatggttt ttactagtgc attcataggc
     3721 gctctaatga aataaatgcg tcttcacagg atgcccggtt caagcccgga tggcaagcct
     3781 cttcttgaat ttccggcgct tttcggattt ttgaaaagcc ggggaaagag attgctgttt
     3841 atcagtttgg aatggttatc attttgttgc ctgttccggc ttgacgaggc tttccgcata
     3901 ggcgtatcgt ctgtgcatga aaagaagtaa aaaggaagtg ctggacgcgg atttcgcagc
     3961 ggcgcgcgcc ggcgttctgg atgtggccgc atttctggac cgggtggacc gcggggaagg
     4021 ggaggcggat ttccgttacc atgccctgat ggatgttctt cccctcttat ccgcatccgg
     4081 ccccggacgc gtccgggcca ttctggaagc cctttcctac agggatgaca ccgtgccgga
     4141 aaccgccgca gccaaagcgg cctgcggagc cccgaacctc agcaaataag aatgatggct
     4201 ttcatagaac ctcatataca tatggtgtgc cgcaccacgg acgaataccg ggccatggcg
     4261 caggccggct gcctggcggt aggggaaccg gcgttctggg ccggttacga ccgttcgtcc
     4321 gcggacggtt tccgggatta tttcgtacag cttacggaat gcgaacccgc cagggcggcc
     4381 aagttcggca tggaccatta cacatggctg tgcatcaatc ccaaggaggc gcaggacgtg
     4441 gctttcgcgc gggatgtaat gaaactgatt ccggagttca tcgaccggcc caatgtcctc
     4501 ggcattgggg aaataggact gaaccggaat acttcccatg aaatgactat ttttgaggag
     4561 catctggatc tggcggtgcg cctcaaccag cttgtgctga ttcacactcc ccatctggaa
     4621 gacaagctta aggggaccgt aatgattctt tccgccctga aaaaccgtcc ggatctggac
     4681 ccttgccgcg tgctggtgga tcactgtgag gaacatacct tcccgctggt gaaggaggcc
     4741 ggctactggg ccgggctgac cctttatccc accagcaagc tgaatcccaa gcgggcggcg
     4801 gatattctgg aattgtacgg aatggaccgt gtctgggcca attccgcggc ggactggggg
     4861 gattccgatc ccctggcgct gacggccttg gcctgcgagc tgcgcaggcg cggtttttcc
     4921 cggcaggaaa cggaacgtct tctcctggaa aatccggaga cattcatggg acagtccccg
     4981 aagttccgga aagtgtcatc ccgctaattc cgcccgcggc gcggcggagg gtacggccct
     5041 ctagtccccg tccgggaaaa agacggtgag gacggcgccc aggatgaccg ccgcgtcatc
     5101 cagaaggccc agcctgccga ttccgtcaaa caggaattcg tcgggagtca ggatgtaggc
     5161 gccggcggcg gccagaaggc atatattccg tttgttgaaa aaacgcggtt ctccttttct
     5221 gcttttgaaa taccggaaca ggcgcagtag cagctgctgt ttttgaaggt tcatggacgg
     5281 gaacggggga taaaggttca agctcagcca ttttcccact ccttttccct gtttcgggga
     5341 aggagtctgt tgccgacgga cggaaaccgc agcgatccgg accgtgcggg gaaatggatt
     5401 gctgaaagga tgggctgttc cggatgctga gggaagccgg gctttgcatg ctccggttcc
     5461 ggctgtcccg gcatgggaaa aaggggcgtg tacggaagtg gggcggggcc ggaagctctt
     5521 gaaatgaccc tcccggggga gcctgaatgc catttccccg tcaagtgctg gccgtgaggg
     5581 taccgcagca aatggaagct tcttcccccc tgttttttcc ggcagatgtt tgaacggata
     5641 aggaaaaggc cggctcacga ttttgtgagc cggcctttga atatagggag gcggacggta
     5701 caggcttatg ccctgcggcg gcgcatcatc agcgcggcca gtcccagcag gcccagggaa
     5761 gccgtggcgg gttccgggat gctggcgatt tcactcatca gttgaccaac ttgttcctgg
     5821 gaaaggaggg agtcgtgaat gtagagctgt tcgatggatt cagccagtcc tgcgtccatg
     5881 agaatctgat caatttgctg gttgccgaat ttcaggccgc tgttggaata gtacgtagcg
     5941 ctgtctccaa aatagatgcg ggtgccaaga tctccggtga ctacggaaat ggtcagggaa
     6001 ccttccgtgc ccagcggggt gtcaacgacg ggcccgttgt atgaggtgtt gttccataat
     6061 ccctggagtt tccggtccgt gttcaggccc acgccccagc ttacactgct gtttttggcg
     6121 ttaaacagag cggtataggt ctccggagtg ttgattttgg acaggtcaag aaccatcgtc
     6181 acagacataa cgtcgcggtt gttggcaccg tatccgttga aggttatccc ggacaacgtc
     6241 agattgctgt cgtcagacgt gatggaaacg gaatctttcc gggtgccgaa atccgccgtt
     6301 tgggaggcaa agtccgaata tcccacgatg gagctatcca acagagcggt agccgcggta
     6361 gcgcttaggc tcatgccggc cgaaagaatc agggtggata ataatttatt catggtcagt
     6421 atcttaataa aatgattcaa ggttcaatgt atgtacttgt gcttgaataa cgaatttgga
     6481 atccgcaagc aattaaaaat attaagagtt agtatattgt atttataatt cattgaaaat
     6541 aatgattttt taatatctct ggtccttttg ctaagatgac gggtcagtct ttgttattca
     6601 ttggtttcat gattgatttg gcctcttttt cattacttga cggattccaa attcgattgg
     6661 ggaattccaa attcgctaca agttgccatc caaaaggaat aataaatatg aagaaaacac
     6721 tgacattttt aatcgcgatg ggaagctttg ctgtttcctc ggaggcagcg accgttttta
     6781 attattacac tcccggtacg gataattaca atagtaccat ccatgggttt tatcttggcc
     6841 tggggtcttc ttccctggct ccttccgatt cctcttctcc ctcctccctg tccggagaga
     6901 tcagactgga cagttttacg ctgcgcggag ccgccaacaa tttgggcgct aatgtcactt
     6961 acggcttcct ggtgctgaat ggctccgaca attcggtcat cggctggagc accaatacgg
     7021 gaactactgc agcagggatt aatctgacgt tcagtttttc ttccctggat ggttctcccc
     7081 tgcttcttga cgcggcattg acataccgtt tcctggccgt gagccagtcc gtgatggact
     7141 tgatgcagga tacgtctaaa acgtatttat atgctgcggg gggaacagcc gcccctactg
     7201 ctaacacgga aggagatacc gtaacgatca gcggcggatt gactgctccc ggcatccgcg
     7261 gccattatga cgccgaggga gcgcctggtg attctgtcgt tattacggga gccaacggaa
     7321 ccaatacttt cagcttatta tccccgattt tcacggaaat ccgaggggaa atggtgccgg
     7381 aaccagccac ggtttccctg ggcctgctgg gactggccgc gctgatgatg cgccgacgca
     7441 gggcttgagc ttcctgatgg cgaaaaatcg gcggatgaga gctgttcttg cggaacagct
     7501 cttgtttttt atatccagag aggaagaatt gcttatccgt atgcgggatt catgccctcc
     7561 ggaaggtacg gaatttccgg gggcaggggg ccgtatccgg ttttttcggc atggcggcaa
     7621 tttgctggaa acgtttttga gacgcagtac cggaaagctt tttctttacc ggaaaatgcc
     7681 gtcaaattcg gcagcgcgct tttcgtccat atggtacacg gcagctttca catagtggcc
     7741 tttcaggccg gatagggaac ccctttgcag ctcacagacc tggagggccg ccgcatacat
     7801 attattcgcc gtcctattcc ccggcgctgg tatttcggaa gaacggcaat gggccccatg
     7861 cccagcactt catattcttt tccatcgtct gccctgatga cggacgttgc atcaacgatg
     7921 tttcccgacg atgcggctgc cgtggacggc gactgcatcc agctccggga tgaaggacgg
     7981 actgacgcgc atgatatgga gcaggtaatg ttcatggcag ccggggacga aatagttcca
     8041 gaacgcttct ctcgtgacat gttccgtttc ggcatggtct gaggattgtt ccgttcttaa
     8101 tgcaatggtc atgaaaggtt gttctttacg gctccccctt ggagaaattc cagaggcggt
     8161 gcatcgtcat aatgtccgga atgttcatgg ggcgcaccac gcggaacccg atcatgcctc
     8221 cgtccgtcag gtaccagatg cttttagggt tttgaggatc ctgacggctc caggcggggg
     8281 tgctggcgcg gcgcgcagcg cttctcaggc tgtccgggtc gtcttcccac gaaccgccgc
     8341 gaacgatgtg aggggcgccg gggatgatga ccaaggggtc tttcgcgggc aagccgctcc
     8401 gtttgccgta ggcatccgga acgtaagagt ccaaaaccca ttccgccaca tttccgtgca
     8461 tgtcccggag tccccactta tttggttttt tagagcctgt tttctggtag cggtcattgg
     8521 agttgttcca gtaccaggcg tactggtcca gagaggcttc cccgtttccg taagaatagg
     8581 cgccggggga gccggcccgg caggcgtatt cccattccgc ctccgtgggc aggcggtagt
     8641 aatgcccggt ctgggcgctc agccattcgc agaatttgct ggcggcgtgg tgggacatgg
     8701 agatggcggg cagaccgtgt tcatagccgt ggcccatgcc caggttcatg gcggtgtagg
     8761 gggcggtagg ctgcgtaacg gagtcccaca gttcgtcatc cggctgttcc tccagaagct
     8821 ggccgtcctt ggcgcgcgga cgcccgtttt ccatgaaggc cgtataaagt tcccagggga
     8881 tttccgtttc cgagatccag aagggggaga tgctcacttt atgctgcgga ccttcgtccg
     8941 gtttccggtg cggctcttcc gcgggactcc ccatgaggaa cgttcctccc ggtatggcga
     9001 ccatgcgcag ggaagctccc gccacgggaa ccgtttccgt gtaggattca aaacgtgccg
     9061 gatttccgga agcttcaatg agctgatgga tttggcgcgt tgtgccgacc agctcccggg
     9121 acggcaggtc atccggaatg ggaagggcag gaccggcagc gcggtccagt tcccgttttt
     9181 gcagcgcgga tcggctttct ccccactggc gtgcgctggt aatgcgcgcg gcatcttccg
     9241 tggccgggcg gggggaatta ttttcttccc ggcacccggc cagcagggcg cttcctccca
     9301 gaaagcagga aacaaggaaa atgccgcgca tggaatggag aaaaccggaa tgccctacat
     9361 cgtcatgcct ccgtcgcagg caatgacctg cccggtgatg taacgggcat cgtcagaggc
     9421 aaggaaggcc gtcagggcgg cgatatcttc cacggaacct tgttctttca aaggtatttt
     9481 cttaacgatt tcttccttga gattgtcggg aatggaattg gacatttccg tggagatgaa
     9541 gccgggagca atggcgttgc acgtgacttt gcgcggagcg aattcctgag ccagtgattt
     9601 ggtgaaaccg atgagacccg ccttggaagc ggcgtaattg gcctggccga tgttgccgac
     9661 gagaccgatg acggagctca tgttgatgat gcgcccggcc ggggatttca tgagaacgcg
     9721 ctggagggcc ttgaccgtat tgaacgcgct tttcaggttg gtgtccagaa cagcatccca
     9781 gtcttcctct ttcatgcgga gcatcaggga gtcccgcgtg atgccggcgt tgttcaccag
     9841 gatgtcaatc tgcgggaagt ctttcaaaat ggcggccatg gtttcctgaa cggccgcgta
     9901 atccgctacg tcgcaggggt aggccttgca ggaatccgga aattccttgt tgatttcttc
     9961 tgcggccccc ccgcagctgg atggactgcg gctgatcagg atgaccctgg ctccttccga
    10021 agcgaagcgg cgcgcgacgg cattgccgat tccgcggccc gcgccggtaa cgatggctgt
    10081 tttacctgct aacttttgca tgctgcccac agtaaacccg tttttcacgg ttccggcaag
    10141 cttgaaatgg acttggccgc gcaggaaccc atacggggaa ggggcgtgcc gggaatgaaa
    10201 aaagaggggg ggagaaacgg ggcggggggc tactgtccgg cctcttcatt ttcccggagt
    10261 gcaccggggg gcgtcccgtc ttcatccggt tctaccaggt cgctgaattc atccgaattt
    10321 tccaaaatgt cctttaaggc ggcggaaccg taatagcggg cctcaaacag gcgtttgcct
    10381 tcctgcctgc agcggttgtc cagcatttcc attcgttttt ccattttttc tatcaaggcg
    10441 tcttctttct ccttttccgc atcgttcaat ttatcctgaa gctggaggaa atgccggatg
    10501 tccttctgaa tgtcctgcag cgttttgacg gcgttgtccg cgctttcctt gtcctgaacg
    10561 cctgccaacg tctgctggat attgatggca aaggaaaagg cctggttgat cagggattcc
    10621 gcggaaggaa ttttttccgc cggagccgct gctgcggggg aagccgttcc ggcggccgtt
    10681 tcaccaaatg caagagaggc tccggacaga agcgcagaat ataagagagg aacaagaaaa
    10741 gccttcatcc tgttctttta aggcaggatg aaatccacgg caaggaaaaa ggggaaactg
    10801 aaaaaagagc cttattccgc cgtgatgccg cctttttcat cgtccagaat gcctgacttt
    10861 tccagatagt agtcatatcc acctgcgtag gcggtgatgg tcccccggtt cacatgcagg
    10921 gttttttgtg ccagggaacg gatgaagtgc acatcgtggg agatgaagac cagtgttcct
    10981 tcataatgct tcagagcctg caccagggct tctacggaca aaaggtccag gtgggtggtc
    11041 ggctcgtcca tcagcaggag gttgggcgga tccaccagga atttgaccag gctgagccgc
    11101 gatttttccc cgccggaaag aacgctgacg cgtttttcca catccagcct ccggaacagg
    11161 aaggaaccca ggatggaacg cgcttcttcc tcccggattt cagcgctgca tttcatgatt
    11221 tcctccagca cggtattttc cggattcagg ttttccgttc gcgcctggga gaagtagccg
    11281 atgcgcgtcg tggtaccggg agtgcgttgt ccggagtcaa tggggatgat gcccgccagg
    11341 attttgagaa gagtggattt gcccgcgccg ttcgggccta caagaacagt gcgctccccg
    11401 cgttccacca gcaggtccag gttttcataa accctgcggt cgccatagga ttggcagact
    11461 ttttccagct caatgacttt ctgggtgctg cgcggaggct gggggaagtt gaatttaaat
    11521 actttcctgc gggctaccgg tttttgaatg attttcatct tttccagctg cttgatgcgg
    11581 ctctggactt gcccggcttt ggaattgatg gagcggaaac ggtcaataaa ttcctgaatg
    11641 tgcgctattt ccttctgctg gttgcggtag gccgcctgaa gctgctcgaa gcgcacgtcc
    11701 ttttgttgga ggaagtccga gtaattgccg cggtattcca ccagttcttc gttgtcgatg
    11761 tcgtacacgc tttccaccag ctcatccatg aaatcccggt cgtgggaaat catcaggatg
    11821 gctccggggt agtttttcag gtatcgctgg agccacagca gggacaggag gtccaggtgg
    11881 ttggtaggtt cgtccagcat caggaggtcc ggctccagga caaggagctt ggccaggtac
    11941 gcgcgcatga tccagccgcc ggacatttcc cgggcggggc gatggaagtc gctttcccga
    12001 aaggccagcc ctttgagaat tttcttggct ttgggctcca gctggtaacc gttggcggcg
    12061 ttgaaagtgt caatggcttc cgcgtattcc ggcgtatccg ttttgttggc gttttccgcc
    12121 gtccggatgg tgtggatggc ctgttccatt tccggcgtga tgcccagggc gatttccaga
    12181 acggtttcat ccttcggttc gctggcttcc tggggaagat agcccacgat ggcgtattca
    12241 tccatgctga tggagccttc gtccggcgtg tcttctccca gaatcatgcg gaacagggtg
    12301 gatttgcctg ctccgttggg gccaaccaga gccacccgtt ccccccagtt aatggtcatt
    12361 tccgtttccc tgaacaaggt ccgtccggcg tgggattttg tgagattttt gatcgtcagc
    12421 atggtgaaga gaggatgtat tctaccggga tggaaagggg aaggcaagag ccgtcagggc
    12481 ggaggcaggc atttttgaaa gctttactgg atttttacgc gtagtctgct agccttggcg
    12541 cgccatgccg accacgcaga cattcaggct tttgcttgct gccgcccttt tgtgcggatg
    12601 gagttcctgc tgtactcctc cggcggagga ttatatacaa caaccttacg tgcagcagca
    12661 aatgtccggg ctggctaatg ccttcctggc gctgctgccg ccggatcagg cctctcttcc
    12721 cgctgccgga gcggaggcca ggtggctggc ggacacggcc gtggtccagt ccgcagcgat
    12781 tgcccgggac aacaggactg tgctgtttgg ctggctgaac aatattctgg tcaattccaa
    12841 cctgcgcgac agggggctgt gctggcaggt ccagcaggat ttgtaccggg acctgcgccg
    12901 ccgccccgtg aagtatttcc gcatagggct gacgattcga gaccgtggaa cgggcaggga
    12961 gcacagttgc gtgtatgtca atgccgcggg gaagggattg cagggctcca ttgttctgga
    13021 tgcctggaag aactgcgggc atctggtgac gctgacccag aaggaccggg aaggcggcaa
    13081 atgggaggag gactggcggg aaccatttgt ttccaaggcc tttccggagg gccattccta
    13141 cggcatggaa catcacctgg tctggcccgg gtgggccagg aaacgcccca tgctggttca
    13201 gcggatattc cagtccgatc agcagaatga ggcgaaggcg gccgctgaat aaaggggaag
    13261 cctgatccgg caggaaccgg cacacggtgc tgcgccgcgg cggtttgcgg tatccgccgt
    13321 ttttaaggaa aatcccggcg aatcggcaaa tggcggaggg aatccggact cagggcaaat
    13381 aaaaacgcac tcagtgcgta caccgagtgc ggattaattg gataatttgc tagtgttgca
    13441 gggcaaaacc ccgctgcaaa cttacttgcc cttggcctgc acaaccggag cgggagcagg
    13501 agcggtggtt tgctgttgct gctgctgctg ggagcaagaa gcgaccaggc aagcggcgcc
    13561 ggcgatggcg aggatagcga tgttcttcat aattcgaatt aaatacagtg tttgttaact
    13621 actggaacct ccgcatccac ggaggtttgc tggcaccaat gtaaatggtg gcaagtagaa
    13681 atcaagagat tttcttgttc catgtcacgg cattac
//
