LOCUS       c00084_gnlPro..        13467 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|HOFBLCLJ_84.
ACCESSION   c00084_gnlPro..
VERSION     c00084_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-07 16:34:59
            Original ID  :: gnl|Prokka|HOFBLCLJ_84
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 13467
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..13467
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[496:3467]"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      497..3467
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
     cand_cluster    1..13467
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /kind="single"
                     /product="Pyruvate2acetate-formate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..13467
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Pyruvate2acetate-formate"
                     /region_number="1"
                     /rules="((PFL_acetate1 or PFL_acetate2) and Radical_SAM)"
                     /tool="gutsmash"
     CDS             497..2725
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: PFL_acetate1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Gly_radical"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg84_1"
                     /sec_met_domain="Gly_radical (E-value: 1.5e-46, bitscore:
                     148.1, seeds: 99, tool: rule-based-clusters)"
                     /sec_met_domain="PFL_acetate1 (E-value: 0.0, bitscore:
                     1173.8, seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MELNKIFKDGLWSSEINVRDFVSHNITPYYGDASFLEGPTERTKA
                     VWNRCLEALAEERENNGVRSLDNVTVSTITSHKAGYIDKENELIVGLQTDELLKRAIKP
                     FGGINVVSKACHENGVEVDDRVKDIFTHYRKTHNDGVFDVYTEEIRSFRSLGFLTGLPD
                     NYARGRIIGDYRRMALYGIDRLIEAKKEDLHNLTGPMTEARIRLREEVAEQIKALKDMK
                     VMGEYYGLDLSRPAYTAQEAVQWVYMAYLAAVKEQDGAAMSLGNVSSFLDIYLEYELSK
                     GTITESFAQELIDQFVIKLRMVRHLRMQSYNDIFAGDPTWVTESLGGRLNDGRTKVTKT
                     SFRFLQTLYNLGPSPEPNLTVLWSPELPEGFKEFCAKVSIDTSSIQYENDDLMREVRQS
                     DDYGIACCVSYQEIGKQIQFFGARCNLAKALLLAINGGRCENTGTVMVKNIPVLTSDTL
                     KFEEVMDNYKKVLTEIARVYNEAMNIIHYMHDKYYYEKAQMALVDTNPRINLAYGVAGL
                     SIALDSLSAIKYAKVTARRNDIGLTEGFDIEGEFPCFGNDNDKVDHLGVDLVYFFSEEL
                     KKLPVYKNARPTLSLLTITSNVMYGKKTGATPDGRAKGVAFAPGANPMHGRDKNGAIAS
                     LSSVAKLRYRDSQDGISNTFSIVPKSLGATDEDRIENLVTMMDGYFTKGAHHLNVNVLN
                     RDMLYDAMEHPENYPQLTIRVSGYAVNFVKLSREHQLEVISRSFHERM"
     CDS             2739..3467
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: Radical_SAM"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1015:4Fe-4S single cluster domain (Score: 72.5;
                     E-value: 1.4e-22)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg84_2"
                     /sec_met_domain="Radical_SAM (E-value: 4.4e-29, bitscore:
                     92.6, seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MMINVHSYESMGTFDGPGLRLVVFLQGCNFRCLYCANPDTIAGKG
                     GTPTPPEEIVRMAMSQRPFFGKRGGITFSGGEPTFQAKALVPLVRELKEKGIHVCLDSN
                     GGLWNEDVEELFRLTDLVLLDIKEFNPNRHQTLTGRSNEQTIRTAAWLEEQEKPFWLRY
                     VLVPGYSDFEEDIRALGEALGKYKMIQRVEILPYHTLGVHKYEAMGQEYKMKGVKENTP
                     EQLEKAAEVFKEYFTTVVVN"
     CDS             complement(3896..4063)
                     /locus_tag="ctg84_3"
                     /transl_table=11
                     /translation="MKEIVNRILDVIMYLIPFFGKRKRDRVVREVRYHTTCKEVCKVKT
                     TEREKEHEKD"
     CDS             complement(4123..4626)
                     /locus_tag="ctg84_4"
                     /transl_table=11
                     /translation="MAMTVSYSVVPRKNPAKKSEPAKYYAQAQASGELDFEELCEAITS
                     RSTCTETDVRAAISGILYEVKRALKAGRIARLGDLGSLQIGLNSEGAASVKEFSGSMIK
                     GAHLIFRPGKTLAELMKILSYQQVQTRAVAQAGAGDGGGEDPDKNPDSGGDGSGDEEAP
                     DPTV"
     CDS             5185..7251
                     /locus_tag="ctg84_5"
                     /transl_table=11
                     /translation="MTEEEIVSTIGSFTYREKVEEIRRIFAEQGEKAANEKKKELPAIA
                     FSASYRGRRTKVNLVKYLGHIVIDIDHLSKEELARILPIIKRCDYTRIAFISPKGMGVK
                     IIVRACHPDETLPETLQEIEDFHHAAYTRLVSFYTELCQIEIDTSGQDVARTCLFSYDP
                     EIYFNPNADAFLVDQPQASYKVSNRKNLSGSKQQTPPDGPPTNEDTALNAHSANASLVL
                     TLTYYHNKSEKYIAGNRNNYLHHLSCTFNRYGIPQEEASAFIKSQFTDFPADETASLIN
                     SAYAHTDEFNTCKLNGTQKRILRIEQYISEHYETRYNEVLHIMEYRRRHPDTEKPEPFR
                     ILDEMMENSIWIEINELGYPCTVKTIENLIYSDFSQSYHPIREYFELLPEWDGTDYIRI
                     LADSVQTSHQEFWAECLERYLVAMCAAATQENIVNHTVLLLCSEIQNIGKTTFINNLLP
                     PELRAYLSTGLINSNNKDDLAKITQAMLINLDEFEGMSGRELNAFKDLVTRKVISFRLP
                     YARRSQNFPHTASFAGTCNYQEVLHDTTGNRRFLCFHPYSIQFITINYAQLYAQIKYLL
                     NKPGYQYWFTQADNERLEENNEAFIFHSPEEEMVLTHIRKPERFEKVYYLTVSEIAELI
                     RERTGYQYSIGSKIQLGKVMTKHHFESKKGNNGRRYAVFIIDIEQVKSNRLYE"
     CDS             complement(7452..7577)
                     /locus_tag="ctg84_6"
                     /transl_table=11
                     /translation="MSVLVRKEQLLVQRQKKRPTPFIQDRLSRTQEKRLKSLRLN"
     CDS             complement(7607..7780)
                     /locus_tag="ctg84_7"
                     /transl_table=11
                     /translation="MKREIIAYKGYFKEFFENLDAGTQDKILYVLKTEITPKKEIDKAK
                     ILRKEYYGSKNK"
     CDS             7797..8213
                     /locus_tag="ctg84_8"
                     /transl_table=11
                     /translation="MLFNYTTHFLVLYYFSSSSPPKVRGVREELKLFLFYFFISTFYIS
                     LKKIRMLEILSHSSHFLPFLSPKRRREIGKTQPSFFYFSPHFQISPPIEADFRKYLLSL
                     MCKRSKESDMDNLMRKLPIGIQTFEDIRRKNILL"
     CDS             complement(8329..8640)
                     /locus_tag="ctg84_9"
                     /transl_table=11
                     /translation="MSTKNNMLTDISAELDKEFGAPGTPEREKFDEEAYAFYTGQILLD
                     ARREAKVTQSELAKRINATKSYISRIESGAINPSVGTFYRIINALGLKIEIVKPIMGI"
     CDS             complement(8612..8953)
                     /locus_tag="ctg84_10"
                     /transl_table=11
                     /translation="MRRKVIAYGQYYKDFLATLTEKEIQKVKYVLSLLGTEDRLPIKFI
                     KVIRDGLYELRISYNGNIYRIFFIFDEGQIVVLFNGFHKKTQKTPSSEIDKALKIKEEY
                     YEYKKQHAD"
     CDS             complement(9046..9300)
                     /locus_tag="ctg84_11"
                     /transl_table=11
                     /translation="MTPTVIEYRGDPKRYVSVILGAIDRGRLTYNGDANCEQTFRSLSS
                     VIDVISPKNGKALSIETLVSYEKKERAGEFSDYSEGKFE"
     CDS             complement(9318..9452)
                     /locus_tag="ctg84_12"
                     /transl_table=11
                     /translation="MENSLSDELFCSLKNELREVDAQISVHSKKLLGLIDQKKELSSN"
     CDS             complement(9570..10928)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) MFS_1"
                     /gene_functions="transport (smcogs) SMCOG1058:Major
                     facilitator family (Score: 153.4; E-value: 2.6e-47)"
                     /gene_kind="transport"
                     /locus_tag="ctg84_13"
                     /sec_met_domain="MFS_1 (E-value: 1e-47, bitscore: 153.4,
                     seeds: 192, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGFKLLDFYKISPPVSGGETDPERSVRFKRIRWATFLSATTGYGI
                     YYVCRLSMNVIRKPIVEDGVFTETQLGIIGSCLFFVYAVGKLTNGFLADRSNVKRFMST
                     GLLCSALINLCLGFTNSFFAFVLLWGLNGWFQSMGAASGVVSLTRWYSSKERGTFYGFW
                     SASHNLGEALTFISIALLVSWMGWRYGMIGAGVIGLLGFLMMLAFMRDTPQSQGFLLDR
                     WGTSDAHSVSGKQTEEFNKAQKAVLKNPAIWILALSSAFMYISRYAVNSWGVFYLEAQK
                     GYSTLDASFIISISSVCGIVGTVFSGIISDKFFAGSRNVPALIFGLMNVSALCLFLLVP
                     GVHFWVDALAMVLFGLGIGVLICFLGGLMAVDIAPSNASGAALGVVGIASYIGAGLQDV
                     MSGILIEGQKTVQNGVEVYDFTYINWFWIGAALLSVVFALLVWNAGEKRSEIN"
     CDS             complement(10944..11864)
                     /locus_tag="ctg84_14"
                     /transl_table=11
                     /translation="MKKYIMIGILFAFPFCLSADEPVKAIYAKITNPDNKEITVVAHRA
                     DWRYAPENSLAAIESSIRLGADVVELDVQKTKDGQLILMHDKTLDRTTTGKGKVAEWTL
                     DSIRTLYLKNGAALKTKHRVPTLEEALWVAKGRVMVNLDKAYPIFDEIFPILEKTGTVD
                     QIIMKGSKPVADVKKDLGKYLDRIIYMPIIHLDKPGAMKQLDDFMTELHPVAFELLFVS
                     DTCQAPKQVKTKLKGKSKIWYNTLWDTMAGGHDDDKSLENPDEGYGYLIDTLGAAIIQT
                     DRTAYLLEYLQSRKKRSENGQDAYH"
     CDS             complement(11879..12979)
                     /locus_tag="ctg84_15"
                     /transl_table=11
                     /translation="LISESDSPLKGDWEAGIGKIWSSPTIGPDGAIYIGVTNTVDPTKS
                     VLVALEDEGITGAATSAWPMKGKDRRHSGAQSGGNGENPGGEEGGQLPVTGNLKADLKS
                     LFESTSYKVWLCAHRGNTQKGMKEGIPENSLPAIEHSVKAGVEMIELDARPTSDGVLVL
                     MHDNTIDRTTNGSGAVGDFTYQQLQQFYLKDASGNITGERIPTLEEAMKKGKGKVYYNL
                     DIVNKNVAVNTIVALLKKLDMEGSTLLYVSNNRNYAFDLKAANSSLLLHPMAKATDDIT
                     YFSSSYTDNVQMMQLSTSDAMGGTMVNEIKDKGWLLFSNIVGANDTNMLSENYSGLVGM
                     INKRINIVQTDYAEVAAKYLKSKGYR"
ORIGIN
        1 atacactttt ggcgtataca cgctttccag gcgtgcctct tcaaccactc gagcatctct
       61 cctttcaaaa aactcaataa acactaagaa aacactcccg ttttcgtttc acaacatcgg
      121 aggcgtcgcc ctccataaaa acaaaaaagc agcccaaaag ctgcttttca gcggagagac
      181 agggattcga accccgggta cctcgcggta caacggtttt caagaccgcc gcaatcgacc
      241 actctgccac ctctccaaaa cttccttatc agaagtgctt ttcgttaaaa gcggtgcaaa
      301 ggtacgaaga tattttaaac ttgcaagagt tttcactaaa aatttaatct aatcttttcc
      361 taaggatagc aattaatagg tattttatgt tgaaaagcat aaaatagagc atatttatgc
      421 tgattatatg aaaaatgatt gtaactttgt gcgctctaaa gaataggata actacaacct
      481 ctaattttat cattttatgg aattaaacaa gatctttaaa gacggtcttt ggagcagcga
      541 aatcaatgtc agagatttcg taagtcataa catcactccg tattacggag atgcttcatt
      601 cctcgaagga cctacagaac gtaccaaagc cgtatggaac cgctgcctcg aagcgttggc
      661 agaagaaaga gaaaacaacg gtgtccgctc attagataat gttaccgtat caaccatcac
      721 ttcccacaag gccggatata tcgacaagga aaacgaactg atcgtcggcc tgcagacaga
      781 cgaacttctg aaacgtgcca tcaagccttt cggaggtatc aacgtagtca gcaaagcctg
      841 tcacgaaaac ggcgtggaag tggacgaccg cgtaaaagat attttcactc actaccgcaa
      901 gacgcacaac gacggagtat tcgacgtata tacggaagaa atccgttcct tccgttcgct
      961 gggattcctt accggacttc ccgacaatta tgcacgcgga cgcatcatcg gtgactaccg
     1021 ccgtatggct ctttacggca tcgaccgtct gatcgaagca aagaaggaag atttgcacaa
     1081 cctcaccggt ccgatgacag aggcccgcat ccgcctgcgc gaagaagtgg cagaacagat
     1141 caaggcactg aaagacatga aagtgatggg cgaatactac ggtctcgacc tgagccgtcc
     1201 tgcttacacg gcacaagaag ccgtacagtg ggtatatatg gcttaccttg ccgccgtcaa
     1261 agaacaagac ggtgccgcta tgtcactggg taacgtttct tctttcctcg atatctatct
     1321 ggaatatgaa ctgagcaaag gaaccatcac cgaatcattc gcgcaagagc tgatcgacca
     1381 gtttgtcatc aaactgcgta tggtccgcca cctgcgtatg caatcataca acgacatctt
     1441 tgcaggcgac ccgacctggg taaccgaatc tctgggcgga cgtctcaacg acggacgtac
     1501 caaagtgaca aagacctcct tccgtttcct gcagacattg tacaacctcg gcccttcacc
     1561 ggaaccgaac ctgaccgtac tctggagccc ggaacttccg gaaggattca aagaattctg
     1621 tgcaaaggtt tctatcgaca cttcttctat ccagtacgaa aatgacgacc tgatgcgcga
     1681 agtacgtcag tccgacgact acggaatcgc ctgctgcgta tcataccagg aaataggtaa
     1741 gcagattcag ttcttcggcg cccgttgcaa cctggccaaa gccctgttgc ttgccatcaa
     1801 cggcggacgt tgcgagaata ccggtacagt catggtgaag aacatccccg tgctgaccag
     1861 cgacacgctg aagttcgaag aagtaatgga caactacaaa aaagtgctga ccgaaatcgc
     1921 ccgcgtatat aacgaagcga tgaacatcat ccactatatg cacgacaagt attactacga
     1981 gaaggcccag atggctcttg tagatacgaa cccgcgcata aaccttgctt acggtgtagc
     2041 cggactttcc atcgccctcg attcactgtc tgccatcaaa tatgcgaaag taactgcccg
     2101 ccgcaatgat atcggtctga cagaaggctt cgacatcgaa ggagaattcc cttgcttcgg
     2161 taacgacaac gacaaggtag accaccttgg cgtagacctg gtatacttct tcagcgaaga
     2221 attgaagaaa ttgcctgttt acaagaatgc ccgtcctacc ctctccttgc tgactatcac
     2281 ttccaatgtg atgtacggca aaaagaccgg tgctactccc gacggacgtg ccaaaggtgt
     2341 tgccttcgct ccgggtgcca acccgatgca cggacgcgac aagaatggtg cgatcgcttc
     2401 tctgagctct gtagcgaaac ttcgttaccg tgactcacag gacggtatca gcaacacctt
     2461 ctctatcgtt ccgaaatcac tgggtgctac ggacgaagac cgtatcgaga acctcgtaac
     2521 gatgatggac ggttacttca ccaaaggtgc ccaccacctg aacgtaaacg tactgaaccg
     2581 tgatatgctg tacgatgcca tggagcatcc ggaaaactat ccgcagctga ctatccgcgt
     2641 ttccggctat gccgtaaact tcgtgaagct gagccgcgaa caccaactgg aagttatcag
     2701 ccgtagcttc cacgaacgta tgtaatctat tactctatat gatgataaac gtacattcat
     2761 acgaaagtat gggaacattc gacgggccgg gcttacggct cgtcgttttt cttcaaggat
     2821 gcaacttccg ctgcctctat tgcgccaatc cggatacgat agcaggaaag ggaggcacgc
     2881 ctaccccacc ggaagaaatc gtccgcatgg caatgagcca gcgccccttc ttcgggaaac
     2941 gaggaggaat cactttctcc ggaggcgaac cgacgtttca ggcaaaagca ctcgtcccgc
     3001 tggtccgcga actgaaagaa aaaggcatcc atgtctgtct ggacagcaac ggaggacttt
     3061 ggaacgaaga cgtagaagaa ttattcagac tgaccgatct tgtgttattg gatataaagg
     3121 aattcaaccc caaccgccat cagacgctca ccggaagaag caacgagcaa accatccgca
     3181 cggccgcctg gctggaagaa caggagaaac ctttttggct acgctacgtg ctagtgcccg
     3241 gatacagcga ttttgaagaa gacatacgcg cactgggaga agcactcgga aaatacaaga
     3301 tgatccaacg ggtggaaata ctaccttacc atacactggg cgtacataag tacgaagcga
     3361 tgggacagga atacaagatg aaaggggtaa aagaaaatac ccccgaacag cttgaaaaag
     3421 ctgcggaggt attcaaagag tatttcacta cggtggtagt taattaatgg agaattctcc
     3481 aatgacctca aagcaagggc attctttaat ccgttcccaa ggatctacga tcccattata
     3541 gttggtgtcg ggacttaaat cccgatgccc tactacttta gcttccggat aacgctgcaa
     3601 caattcgtgt accaagcgat gtagcgcctc cttctgacgg ggtgtacgcg tatccgcagc
     3661 ttttccattc tcatccagac cgccctcata acatacacct aagctgatcg cattatagcc
     3721 acgtgcatga gctccgaccg tatcttcatc ccgcatcggc tcaatctcgc ccgacttgcg
     3781 tatataataa tgataccccc agcacgaaaa gccacgataa cggtgagccg tatccacatc
     3841 ctttgccgta aagtcgcaat cgacacgggt ggcggaacaa tggatcacaa tcagactaat
     3901 ctttctcatg ttccttttcc ctttccgtcg ttttcacttt gcacacctcc ttacaggtag
     3961 tatgatagcg cacttctctc accaccctgt cccgctttct ctttccgaag aaaggaatca
     4021 gatacatgat cacatctaaa atccggttta ctatttcttt catcttatca aaatattaat
     4081 ggaagttatt ctaattcgtt attaccttga cccgtctgcc aattataccg tagggtcggg
     4141 agcctcttca tcaccggagc catcaccacc ggaatccgga ttcttgtcag ggtcttctcc
     4201 cccgccatcg cctgcacccg cctgcgccac cgcacgagtc tgcacttgct gataactcag
     4261 aatcttcatc aactccgcca gcgtcttacc ggggcggaaa ataagatgcg cccccttaat
     4321 cattgaaccg gaaaattcct tgaccgatgc cgcaccttca ctgttcagtc ctatctgcaa
     4381 actgcccaaa tcgcccagtc tcgcaattct tcctgccttc aacgcacgtt tcacttcgta
     4441 aagaataccc gaaatagccg cacgtacatc cgtttccgta caagtagaac gactggtgat
     4501 cgcttcgcac aactcttcaa agtccagctc acccgacgcc tgcgcctgtg cataatactt
     4561 tgccggttcg ctcttttttg caggattctt gcgcggcacc actgaataag atactgtcat
     4621 tgccataata aaataatttt aaagtttata atacatagga tgcatcccct tcttgttaac
     4681 agcacaaaga taaggatagc cggacaagcc atattcccca acgaagtttc ttgattccca
     4741 acgaataaaa acgaagtcaa acctttgaat aacaaggaat tttatgtaac tttatagcat
     4801 aaaacaagaa gaaaacatca tgaattacaa agaagattct ttccttatcc gcacctatac
     4861 caaagcggaa ctggctcacc tttacaatcc ccatgtctgc ctcaaagttg ctttacaaat
     4921 acttcgtcgt tggattattt acaacctccc tctcctgcac gaactcgaac aggaaggcta
     4981 ccgcgcacgc aaccgtctcc tttcgccgaa acaagtggca actatcatac actttttggg
     5041 cgaaccgtag taacttattg ccattttata caaagttcct ttacacattt ccgcaaagaa
     5101 gttcctttgc atcgacaaac aataatcaaa ataaaaatga aacatttcac catatttcaa
     5161 ggtttctact acgcaatagc agagatgacc gaagaagaaa tagtgtccac tatcggcagt
     5221 tttacctacc gggaaaaagt cgaagaaata cgccgcatct ttgcagagca aggagaaaag
     5281 gctgccaatg agaagaaaaa agaattgccg gcaatcgcct tctccgccag ctaccgagga
     5341 aggcgtacca aagtgaacct cgtcaaatat ctgggacaca tcgtgataga catcgaccac
     5401 ctcagcaaag aagaattggc acgcatcctc cctatcatca agagatgcga ttacacccgc
     5461 atcgccttta tcagccccaa agggatgggc gtgaaaatca tagtacgcgc atgccatccg
     5521 gatgagacat tgcccgaaac ccttcaggaa atagaagact tccatcatgc agcttacacc
     5581 agactcgttt ctttttacac cgaactctgt cagatagaaa tcgacacctc cggtcaggat
     5641 gtggcacgca cttgtctgtt ctcttacgat ccggagattt atttcaatcc gaacgctgac
     5701 gcttttcttg tagatcaacc tcaggcatcc tacaaggttt caaatcgtaa aaatctctcc
     5761 ggcagtaaac aacagactcc tccggacggc cccccgacga atgaagacac agcgctcaac
     5821 gcccattccg ctaacgcttc tctggtgctg actttaacct actatcacaa caagtccgaa
     5881 aaatacatag cgggcaaccg gaacaattat ctgcaccatc tctcatgtac cttcaatcgc
     5941 tacggcattc cgcaggagga agcatccgcc tttatcaaaa gccagtttac agactttccg
     6001 gcggacgaga cagcctcttt gatcaatagc gcctacgctc ataccgacga atttaatacc
     6061 tgtaaactga atggcacgca gaaacgaata ttacggatag agcaatatat cagcgagcac
     6121 tacgaaacac gctacaacga agtgctgcat atcatggaat atcgcagaag gcatcccgac
     6181 accgagaaac cggagccttt ccgcatcttg gatgagatga tggaaaacag tatctggata
     6241 gaaatcaacg agctgggata tccctgcact gtcaaaacaa tcgaaaatct gatttactcc
     6301 gatttcagcc agtcgtatca tcccattcgc gagtattttg aattactgcc cgaatgggac
     6361 ggaaccgact atatccgtat cctggcggat agtgtccaga cgagtcatca ggagttttgg
     6421 gcggaatgcc tggaacgtta tctggtggcg atgtgcgcag cggctactca ggagaatatt
     6481 gtcaatcaca cggtacttct gctatgcagc gagatacaga acataggaaa gactaccttt
     6541 atcaataatc tcctgcctcc cgaactgcgt gcttatctct ctaccggact aatcaattcg
     6601 aacaataaag atgatttagc caaaataacg caggctatgc tgatcaatct cgacgagttt
     6661 gaagggatga gcggccggga actgaatgca ttcaaagatt tggtaacgcg caaagtgatc
     6721 agtttccgtc tgccttacgc acgccgttcg caaaacttcc ctcatacggc ctcttttgca
     6781 ggaacctgca attatcagga agtgcttcac gacacgacag gcaaccggcg tttcctttgt
     6841 tttcatcctt attccatcca atttattacc atcaattatg cgcagctcta tgctcagatc
     6901 aaatatctgc tgaataagcc gggatatcaa tactggttca cgcaagcgga caatgaacgg
     6961 cttgaagaga ataacgaggc tttcatcttt cattcaccgg aagaagaaat ggttcttacg
     7021 catatccgca aaccagaacg tttcgagaag gtttattatc tgactgtcag tgagattgcg
     7081 gaactaatac gtgagcgtac cggttatcag tattccatcg gatcaaaaat acagttgggg
     7141 aaggtgatga ctaagcacca ttttgaatct aaaaaaggaa ataacgggcg ccgatatgcc
     7201 gtatttatta tagatatcga gcaggtaaaa tcaaacaggc tgtatgaata gaagcgggaa
     7261 agccttgtga atatagcaaa atgcagagtc atcttgacag atactctgca tttattgttt
     7321 ttacaaaatc attgaaaatt cgattttaca gcctaacgca ttcattatac gatagaaagt
     7381 agatacttta ggctctgtct gaccactttc tactcttgaa atataagaac ggtcagaacc
     7441 gatacgccgg gctaattcag cctgagtgat tttagccttt tttcttgcgt cctcgataat
     7501 ctgtcctgta taaaaggcgt aggccttttc ttctgcctct gcacgagaag ctgttccttc
     7561 cttaccaaaa cgctcatcta ttaatgcact gacattaaag aattcctcat ttgtttttgc
     7621 ttccataata ctcctttctt aatatctttg ctttatcaat ttctttcttt ggtgttattt
     7681 cggttttcag cacatacaat atcttatctt gggtgccagc atctaaattt tcaaagaatt
     7741 ctttgaagta tcctttatat gctattattt ctcttttcat aacgcaaata taagaaatgt
     7801 tgttcaacta tacaacacat ttcctcgttt tatattattt ttcatcatct tcacccccaa
     7861 aagtgagagg agtgagagag gaattgaaac tttttctatt ttatttcttt atttctactt
     7921 tctatatttc tctaaaaaaa atacgaatgt tagaaatcct ctctcactcc tctcactttt
     7981 taccttttct ttctccaaaa agacggcggg aaatcggaaa aacacaaccg tcttttttct
     8041 atttctcacc gcattttcaa atcagcccac caattgaagc agacttcagg aaatatttgt
     8101 tatctttgat gtgcaaaaga tcaaaagaat cagatatgga caacttgatg cgtaaacttc
     8161 ctattggaat acaaaccttt gaagatatac gaaggaagaa tatcttattg taaagatcgg
     8221 aatggaattt agtgcagaaa gccggaactt aaatcgttgg ttaatcgaag tgataggaaa
     8281 gtaaaatatg aaaaaccgaa ggattaagat atccttcggt tttttcgact atatacccat
     8341 gattggtttt acgatttcaa tcttcaatcc taatgcatta ataattcggt agaatgttcc
     8401 tacacttgga tttatagctc cgctttcaat acgtgagata tacgatttag ttgcattgat
     8461 tctctttgct aattcagact gagttacttt tgcttcccgt cgtgcatcca acagtatttg
     8521 accagtataa aaagcgtatg cctcttcatc gaacttttca cgttccggag tcccaggtgc
     8581 tccgaactcc ttatcaagtt ctgcgctgat atcagtcagc atgttgtttt ttgtactcat
     8641 aatattcctc ctttattttt aatgccttat ctatttctga tgatggggtt ttctgtgttt
     8701 tcttatggaa gccattaaat aaaacaacta tttgcccttc atcaaaaatg aaaaagatac
     8761 ggtaaatgtt tccgttatat gatatacgta gttcatatag accatcacgt ataaccttta
     8821 taaatttgat aggcaaacgg tcttctgttc caagcaatga aagcacatat ttcacttttt
     8881 gaatttcctt ttctgtcaga gtggcaagaa aatccttgta atattgaccg tatgctatta
     8941 cttttcttct cattgtgcaa atataataaa agtttcaata tcatacaact tttaaagtcg
     9001 aatttatact gctaacgggc ttaaattccc tctcaggtac tcattttatt cgaatttccc
     9061 ttccgaataa tctgaaaact ctccggcacg ttctttcttc tcatacgaga ccaacgtttc
     9121 gatactgagc gctttcccgt tcttagggct tatgacatct atcacacttg acaaggaccg
     9181 gaacgtctgt tcgcaattcg catctccatt atacgtcaac ctcccccggt caatggcacc
     9241 tagaataaca gaaacatacc gtttcggatc tccccgatat tcgataacag tgggcgtcat
     9301 ttgttcttct tcccgaatca gttggacgac aattcttttt tttggtcaat cagccccaac
     9361 agttttttac tatgcacact gatttgtgca tctacttcac gaagttcatt cttcaatgaa
     9421 caaaacaatt catcactcaa tgaattttcc ataaaaacga tttttattaa ttataaaaaa
     9481 gccattccgg aaagcacagc tattgcctgc ttcccgaaat ggtgactaat accttcaaaa
     9541 acaatgactc tatttttact ttaatgtact caatttattt cacttctttt ctctcctgca
     9601 ttccaaacca acaaagcaaa cactactgaa agcaaggctg caccaatcca aaaccaattg
     9661 atatatgtaa aatcgtaaac ttctactcca ttttgcaccg tcttctgacc ttcgatcaga
     9721 atgccactca tcacatcctg caaaccggct cctatataac tcgctatacc gacaactccc
     9781 aaagcggctc ccgaagcatt gctgggagca atatcgacag ccatcagtcc tcctaaaaaa
     9841 caaatcagca ctccaatgcc caaaccgaag agcaccatcg ccaaagcatc cacccaaaaa
     9901 tgtacccccg gaaccaatag aaacaaacaa agagcagaca cattcattaa tccgaatatc
     9961 aaagccggaa cattacgact gccagcaaaa aacttatctg aaataatacc tgagaaaacc
    10021 gtacctacaa ttccgcatac agaactgata gatataataa aactagcatc caaagtagaa
    10081 taaccttttt gcgcttccag atagaaaaca ccccagctat tgactgcata acggctgata
    10141 tacataaaag cactggataa tgcaagaatc caaatagcag gattcttcaa aactgctttc
    10201 tgagctttat tgaattcctc ggtttgctta ccggaaacgg aatgagcatc tgacgtcccc
    10261 caccgatcta gcaaaaagcc ctgactttga ggcgtatcac gcataaaagc aagcatcatc
    10321 agaaaaccaa gcaaaccaat cactcccgca ccgatcatcc cataacgcca tcccatccaa
    10381 ctgaccagca aagcgatgga tataaaagtc agagcttcac ccaaattgtg gctggccgac
    10441 caaaagccat aaaaagtacc tcgctcttta ctactatacc aacgagtcag cgacacaact
    10501 cctgatgctg cccccatcga ctgaaaccaa ccattcaacc cccaaaggag aacaaaagca
    10561 aagaaagaat tcgtgaatcc cagacataag ttgatcagag cagaacacaa taatccggta
    10621 gacataaaac gctttacatt gctacggtca gcaagaaagc cattggtcag cttaccgacg
    10681 gcatatacga aaaaaaggca ggaaccgata atccccagtt gggtttcggt aaaaactccg
    10741 tcttctacaa tcggtttacg gattacattc atactcaaac gacaaacata ataaatgcca
    10801 tatccggtag tggcagacag aaaggtagcc caacgaatac gcttgaaacg gacagagcgt
    10861 tccggatcag tctctccccc ggacaccgga ggagagattt tataaaaatc caatagttta
    10921 aatcccataa agaagtctat attttaatga tacgcatctt ggccgttttc actacgcttc
    10981 ttacgcgatt gcaaatattc cagcagatag gcagtacggt ctgtctgaat gatggccgct
    11041 ccgagtgtat cgatcagata accatatcct tcgtccggat tctccaacga tttatcatca
    11101 tcatgtccgc cagccatcgt atcccacaac gtattatacc agattttact ttttcctttc
    11161 aacttcgttt ttacttgctt gggggcctgg caggtatccg atacaaatag aagttcaaaa
    11221 gctacgggat gcagctccgt cataaaatca tccagttgct tcattgctcc cggcttatcc
    11281 aaatgaatga taggcatata aatgatacgg tccagatatt tacctaagtc tttctttacg
    11341 tctgccacag gcttggaacc tttcatgata atctgatcca ctgttcccgt cttttcgagg
    11401 atgggaaaaa tctcgtcaaa tatcggatat gctttatcca gattgaccat cacacgacct
    11461 ttggcaaccc ataaagcctc ttccaaagta ggtacacgat gcttggtttt gagtgccgct
    11521 ccatttttca gatagagtgt ccggatagaa tccaatgtcc attcggctac ctttcctttt
    11581 ccggtagtcg ttcggtccag cgttttgtca tgcatcagga tcaattgacc gtctttggtt
    11641 ttctgaacat ccagctccac tacgtcagct cccagacgaa tggaactttc aatagcggca
    11701 agtgaatttt cgggtgcgta acgccagtct gcccgatgag ctacaaccgt gatttcttta
    11761 ttgtcagggt tcgttatctt cgcataaatg gctttcaccg gttcgtctgc cgacaggcag
    11821 aaaggaaatg cgaataagat tcctatcatt atatatttct tcatatctat atgtactatt
    11881 atctgtatcc tttagacttt aaatatttgg cagctacttc agcatagtct gtttgcacaa
    11941 tgttgatgcg tttgttaatc attcccacca aaccggagta gttttccgac aacatattgg
    12001 tatcattcgc tccgacaatg ttggagaaaa gaagccagcc tttatcttta atctcattaa
    12061 ccatcgttcc acccatagca tctgacgtag acagctgcat catttgtaca ttatcagtgt
    12121 aggatgagga gaagtatgtg atgtcatcgg tagctttcgc catcgggtgc aacagcaaac
    12181 tactgttggc tgccttcaaa tcaaatgcat aattgcgatt gttggataca tacagcaaag
    12241 tggaaccttc catatccaat tttttaagca atgcgacgat cgtatttacc gcaacattct
    12301 tgttgacaat atccagatta taataaactt ttccttttcc tttcttcatc gcttcctcca
    12361 aagtcgggat tcgttcgcca gttatattgc cggatgcatc tttcagataa aattgttgta
    12421 attgctgata agtaaagtct cccaccgcac cgctaccgtt tgttgtccgg tcgatggtgt
    12481 tgtcgtgcat caataccaac acaccgtcag aggtcggccg tgcatccagc tcgatcatct
    12541 caactcctgc tttgaccgag tgttctatcg caggtaacga gttttcggga atcccctctt
    12601 tcatcccttt ttgggtattt ccacgatgcg cgcagagcca cactttataa gaggtgcttt
    12661 caaacagact ctttaaatct gctttcaaat tccccgtcac aggcaactgt cctccttctt
    12721 ctccaccggg attctctcca ttccctcccg attgggctcc ggagtgacgt ctgtccttcc
    12781 ctttcatcgg ccaggcagag gttgcggccc cggtaattcc ctcatcttcc aaagctacca
    12841 acacgctctt tgtagggtcc accgtattgg tgactccgat ataaatcgct ccatccggtc
    12901 cgatggtagg cgaactccag attttaccga ttcccgcttc ccaatctcct tttaaaggag
    12961 agtcactttc actaatcaac gcagcaaggt cttttttcag aatcaattgt tcatccgatt
    13021 cttccggttt aatgatataa taattgccgg actgggtgcc gaaatgtatg tttcctgctt
    13081 gatcaattgc cgcacaaccg cttacatctt ccgcaatgcc gtaatgccat tggatagctc
    13141 ctcccggaga caaagagatg attcctccgg ttgcttcccc cggagcacgt ttcactgtaa
    13201 cgataatgct tccgtcgagt cctatcacaa caccgccttg atccagcgtg ccgacattgc
    13261 ccaaaggagt acgccacttc tccactccat cacttcctat agcaaatgcg ctacttccca
    13321 ttcctgcaaa cgtagctgtt ccgtaaatag taccagcctc atctactgcc ggagaaccgt
    13381 tcatattttc tgacggctta tcatcgccgg agctaaatac ctgccaagcc cacattacat
    13441 ttccaccggc attcaacgca gaagcag
//
