LOCUS       c00061_gnlPro..        15102 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|PEDDOBKN_61.
ACCESSION   c00061_gnlPro..
VERSION     c00061_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-05 15:10:35
            Original ID  :: gnl|Prokka|PEDDOBKN_61
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 15102
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..15102
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[2:5102]"
                     /cutoff="2000"
                     /detection_rule="(Complex1_51K and minimum(5, [FMN_bind,
                     FeS, Fer4, Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N,
                     SLBB]))"
                     /neighbourhood="10000"
                     /product="Rnf_complex"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      3..5102
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="(Complex1_51K and minimum(5, [FMN_bind,
                     FeS, Fer4, Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N,
                     SLBB]))"
                     /neighbourhood="10000"
                     /product="Rnf_complex"
                     /protocluster_number="1"
     cand_cluster    1..15102
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Complex1_51K and minimum(5, [FMN_bind,
                     FeS, Fer4, Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N,
                     SLBB]))"
                     /kind="single"
                     /product="Rnf_complex"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..15102
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Rnf_complex"
                     /region_number="1"
                     /rules="(Complex1_51K and minimum(5, [FMN_bind, FeS, Fer4,
                     Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N, SLBB]))"
                     /tool="gutsmash"
     CDS             3..770
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: FeS"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Fer4"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_7"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_6"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1016:4Fe-4S dicluster domain (Score: 38; E-value:
                     6.5e-12)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg61_1"
                     /sec_met_domain="Fer4_7 (E-value: 2.7e-12, bitscore: 38.0,
                     seeds: 208, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4 (E-value: 1.6e-09, bitscore: 28.2,
                     seeds: 528, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_2 (E-value: 8.7e-09, bitscore: 26.0,
                     seeds: 214, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_6 (E-value: 9e-09, bitscore: 26.1,
                     seeds: 134, tool: rule-based-clusters)"
                     /sec_met_domain="FeS (E-value: 2.4e-09, bitscore: 27.6,
                     seeds: 364, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 1.2e-05, bitscore: 16.6,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="QANCGGCGYPGCSGFADACVKAGSLDGKLCPVGGQPVMTKIAEIL
                     GLDAAAAEPMVAVVRCNGTCANRPRVNQYDGAKSCAIAASLYGGETGCSYGCLGCGDCV
                     AACQFDAIHMNPETGLPEVDEEKCTACGACAKACPKSIIEIRPQGKKSRRIYVQCVNKD
                     KGAVARKACTVACIGCGKCVKVCPFEAITLENNLAYIDPNKCKSCRKCEEACPQNTIIA
                     LNFPPRKPKADDTAPQVKVAVPKAEVETPKAEV"
     CDS             831..2168
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: SLBB"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: RnfC_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Complex1_51K"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_10"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg61_2"
                     /sec_met_domain="Fer4_10 (E-value: 4.1e-09, bitscore: 27.3,
                     seeds: 59, tool: rule-based-clusters)"
                     /sec_met_domain="SLBB (E-value: 8.4e-16, bitscore: 48.5,
                     seeds: 67, tool: rule-based-clusters)"
                     /sec_met_domain="Complex1_51K (E-value: 2.4e-49, bitscore:
                     158.0, seeds: 88, tool: rule-based-clusters)"
                     /sec_met_domain="RnfC_N (E-value: 1e-29, bitscore: 93.4,
                     seeds: 53, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 7.8e-05, bitscore: 14.0,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLKTFSIGGVHPHENKLSAHQPIIKAEIPAKAAILLGQHIGAPAK
                     PIVAKGDVVKVGTKIAEPGGFVSAAIHSSVSGKVAKIDTIVDASGYAKPAIFIDVEGDE
                     WEESIDRSETLVKECSLTSEEIVKKIADAGIVGLGGACFPTQVKLCPPPAFKAECVIIN
                     AVECEPYLTADHQLMLEHAEEIMVGVSILMKAVKVNKAFIGIENNKPDAIQLMTKVASS
                     YAGIEVVPLKVQYPQGGEKQLIDAVISRQVAAGALPISTGAVVQNVGTAFAVYQAVQKN
                     KPLFERVITVTGKSLAKPSNFLARIGTPMKQLIEACGGLPEDTGKIIGGGPMMGKALVN
                     TDVPTAKGSSGILIMNEKEAKRGEVQPCIRCAKCVGACPMGLEPYLLATVSAHGDFERV
                     EKEDIMSCIECGSCQFTCPSNRPMLDYIRLGKGKVGAMIRARQAKK"
     CDS             2175..3167
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: NQR2_RnfD_RnfE"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg61_3"
                     /sec_met_domain="NQR2_RnfD_RnfE (E-value: 4.4e-119,
                     bitscore: 387.9, seeds: 472, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNKLIVSLSPHVHGGDSVKKNMYGVLIALIPAFLVSLYFFGLGAL
                     IVTATSVAACLFFEWAIGKFLMKKETTTITDGSAIITGVLLAFNLPSNLPIWIIILGAL
                     FAIGVGKMSFGGLGCNPFNPALAGRVFLLLSFPVQMTTWPAVGQLTAYTDATTAATPLA
                     IMKGVINGAPGMSLSDLPGAFDLLIGNNGGCLGEVSALALLLGLFYMLWKKIITWHIPV
                     SILVTVFVFSGIMYLVNPELYVSPVVQLLSGGLMLGAVFMATDYVTSPMSHKGMLIYGV
                     CIGLLTVIIRLFGAYPEGMSFAILIMNAFTPLINTYVKPKRFGEVAKKK"
     CDS             3185..3829
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: FMN_bind"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg61_4"
                     /sec_met_domain="FMN_bind (E-value: 4.9e-24, bitscore:
                     75.6, seeds: 891, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LKNMLLVLTGVTAISVALLAYVNELTKEPIAQANAKTLSDAVSAV
                     VPGFDNDPIAEKKMQEVNGVQYSVYPATKGGEYIGAAVEAVAMGFGGELKVLVGFDAEG
                     KIIDYSLLSHVETPGLGSKAADWFKKGNKGDITGMNPGEAALTVSKDGGKVDAITASTI
                     TSRAFLNAVNAAYAAYAGQETADGTTGATQKNVEQPADSAAPEAVDTLSAK"
     CDS             3768..4430
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Rnf-Nqr"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg61_5"
                     /sec_met_domain="Rnf-Nqr (E-value: 4.1e-71, bitscore:
                     229.3, seeds: 650, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLNNLLIPQLPKLWIHSALNKKGVEDMNNFKVMMNGIIKENPTFV
                     LLLGMCPTLGTTSSAINGMGMGLATMFVLICSNVVISAIKNLIPDMVRIPSFIVVIASF
                     VTLLQMIMQAYVPALYATLGLFIPLIVVNCIVLGRAEAFAAKNNPVASLFDGLGMGLGF
                     TIALTLLGAVREFLGTGKIFNLSILPEEYGMLVFVLAPGAFIALGYLIALINSMKKN"
     CDS             4518..5102
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Rnf-Nqr"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg61_6"
                     /sec_met_domain="Rnf-Nqr (E-value: 2.3e-64, bitscore:
                     207.3, seeds: 650, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIMEYILIFISAIFVNNIVLSQFLGICPFLGVSKKVETALGMSAA
                     VAFVLTIATIVTFLIQKYVLDAFDLGYLQTITFILVIAALVQMVEIILKKVSPSLYQAL
                     GVFLPLITTNCCILGVAILVIQKDYDLLTGVVYAFSTALGFGLALTLFAGLREQMSLVS
                     VPKGMQGTPIALITAGLLAMAFMGFSGVVKI"
     CDS             5234..6268
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GDP_Man_Dehyd"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg61_7"
                     /sec_met_domain="GDP_Man_Dehyd (E-value: 1.1e-53, bitscore:
                     173.5, seeds: 258, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKGKILVTGGTGYIGSHTVVELQNAGYEVVIIDNLSNSSADVVDN
                     IEKVSGIRPAFEELDCLDYAGLDAVFTKYKGIKAIIHFAASKAVGESVQKPLLYYRNNL
                     VSLINLLELMPKHGVEGIVFSSSCTVYGQPDELPVTEKAPIKKAESPYGNTKQINEEIV
                     RDTVASGAPINAILLRYFNPIGAHPTALLGELPNGVPQNLIPYLTQTAIGIREKLSVFG
                     DDYDTPDGSCIRDFINVVDLAKAHVVAIRRILENKQKEKVEVFNIGTGRGLSVLELINA
                     FEKATGVKLNYQIVGRRAGDIEKVWANPELANNELGWKAETSIEDTLLSAWKWQLKLRE
                     RGIQ"
     CDS             complement(6903..7541)
                     /locus_tag="ctg61_8"
                     /transl_table=11
                     /translation="MAFLHTFLEFFSVTDNAGFNHFSQQVVAFTCTFSYTGKHREAVLL
                     LRNIINELLDKHRLAYTGATKQTDFTALAIWFQQVDNLDACIKHLLYGSQIFKLRGVAM
                     DGISTCTVQLLHAVDRVAHYVHQAAFDLCTYRHGDGASQRMHCHSSLQAVRTVHSNSTH
                     RVFTNVLLYLYNQSFAVRPFYFQCVVNTRQHHFCLRTFEIDVYYRPDYL"
     CDS             7548..8414
                     /locus_tag="ctg61_9"
                     /transl_table=11
                     /translation="LSKVDYDEVAKSQVSLIFGQMNEPPGARQSVALSGLTVAESFRDM
                     GAETDGPRDILFFIDNIFRFTQAGSEVSALLGRMPSAVGYQPTLATEMGAMQERITSTR
                     NGSITSVQAVYVPADDLTDPAPATTFTHLDATTVLSRKITELGIYPAVDPLESTSRILD
                     PHIVGVEHYEVAQRVKQILQRNKELQDIISILGMEELSDADRTLVNRARRVQRFLSQPF
                     AVAEQFTGVPGTMVSIEDTIKGFKMILDGEVDYLPEPAFLNVGTIEEAIEKGKKLLEQA
                     GGKTIKN"
     CDS             8431..8682
                     /locus_tag="ctg61_10"
                     /transl_table=11
                     /translation="MMKKLHLNIVSPEKELFNGEVESVTLPGTMGSFSILPQHAPIVSS
                     LGTGKLIYATDGEEHELDIQSGFVEMSNGRVAVCIEQQ"
     CDS             8724..9143
                     /locus_tag="ctg61_11"
                     /transl_table=11
                     /translation="VTITKRNYLLHTALLTVLIGIVGGWAYFSINPHHYFGGYPLIPLF
                     FFVFGVFMINMTESCRHRMPGRMLQIYLLMRVMRILVSMIVMLVYCVAVREEARAFLLT
                     FIANYLIYLIYDSWFFFTFEANRKLKKKSNNEKIA"
     CDS             9136..10197
                     /locus_tag="ctg61_12"
                     /transl_table=11
                     /translation="LRNILTVILLALGMLLPATVRAENTVDVKEIVFGHIGDSYEWHIT
                     TWGETHVTIPLPVIVHSSTTGWHAFLSSRLEENGGSYEGFSIAPAGSKYEGKLVEYDAI
                     GNEIRPLDISITKVTLALLINSALLLVIILSVAHWYRKHPQGSAAPGGFIGFMEMFIMM
                     VNDDIIKSCVGPKYRKFAPYLLTAFFFIFINNIMGLIPFFPGGANVTGNIAITMVLAIC
                     TFLAVNIFGTKTYWKDIFWPDVPWWLKVPVPMMPFIEFFGIFTKPFALMIRLFANMLAG
                     HMAMLVLTCLIFISASMGPALNGTLTVASVLFNIFMNALELLVAFIQAYVFTMLSAVFI
                     GLAQEEHKEKAVK"
     CDS             10254..10511
                     /locus_tag="ctg61_13"
                     /transl_table=11
                     /translation="MLLSVLLQAAAAGVGVSKLGAAIGAGLAVIGAGAGIGKIGSSAME
                     AIARQPEASGDIRMNMIIAAALIEGVALLAVVVCLLVFFL"
     CDS             10607..11113
                     /locus_tag="ctg61_14"
                     /transl_table=11
                     /translation="MSLLLPDSGLLFWMLLSFGVVFVVLAKYGFPVITKMVEGRKTYID
                     QSLEVAREANAQLSKLKEESEALIAAANKEQGRILREAMHERDKIIVEARKQAEAAAQK
                     ELDEVKKQIQQEKEEAIRDIRRQVAVLSVDIAEKIIRKNLDEKHEQMEMIDRMLDEVLA
                     ASKNN"
     CDS             11125..11685
                     /locus_tag="ctg61_15"
                     /transl_table=11
                     /translation="MDIGIVSMRYAKALMEYAKSMGAEDTLYKEFCMLDRSFRKHPDLR
                     MALENPILTIREKLTLICTAAVGDAPAGREFARFMTLVLKNRRENFLQYICLSFLDLYR
                     KDKHIGVGKLITAVPVSQEVRERIHDSASSLLHASMELQTEVDPSIEGGFIFDINDFRL
                     DASIATQLKKVKQQFIDKNRRIV"
     CDS             11816..13402
                     /locus_tag="ctg61_16"
                     /transl_table=11
                     /translation="MLSENIKVSEVSDILRKQLEGIDTRVQLDEIGTVLQVSDGVARIY
                     GLRNAEANELLEFDNGIKAIVMNLEEDNVGAVLLGPTDKIKEGFIVKRTKRIASIMVGE
                     GMLGRVIDPLGAPLDGKGLIGGELYEMPLERKAPGVIFRQPVNQPLQTGLKAVDAMIPI
                     GRGQRELIIGDRQTGKTAIAIDTIINQRANFDAGDPVYCIYVAIGQKGSTVASIVNTLH
                     QYGAMDYTIVVAATAGDPAALQYYAPFAGAAIGEYFRDTGRHALVVYDDLSKQAVAYRE
                     VSLILRRPSGREAYPGDIFYLHSRLLERAAKIISQEEVAREMNDLPDSLKGKVKGGGSL
                     TALPIIETQAGDVSAYIPTNVISITDGQIFLDTNLFNQGNRPAIDVGISVSRVGGNAQV
                     KAMKKVAGTLKIDQAQYRELEAFTKFSGDMDPVTALTIDKGQKNTRLLVQPQYSPMPVE
                     KQIAILYCGTHGLLRNVPLDKVSEFERNFLESLEMNYRMEVLDVLKTGAINDDVCKKIE
                     ETAEAVARQFM"
     CDS             13524..14414
                     /locus_tag="ctg61_17"
                     /transl_table=11
                     /translation="MSSLKEVKNRISSVKSTRQITSAMKMVASAKLHKAQGRIENMLPY
                     QRKLNEILTNFLRTDASFESPYTEKRPVTRVAVVAFSSNSSLCGAFNSNVAKMLERALE
                     DYQSLGKENILIYPVGRKVEEAVKKMGYVPQGSYQVMADKPSYVEAYELAEKLMHEFVE
                     KQIDHVELIYHHFKSMGSQVLLRENYLPIDLTQVAQEAAEDVPEDARSFNNDYIVEPSV
                     GELIAELLPKVLSQKIFTVLLDSNTSEHAARMLAMQTATDNANELIQDLTKQYNKSRQQ
                     AITNELLDIIGGSLK"
ORIGIN
        1 cccaggcaaa ttgcggtgga tgtggttacc ccggttgtag cggatttgca gatgcttgcg
       61 taaaggcagg ttcgctggat ggtaaacttt gtccggtggg tggacagccc gtcatgacaa
      121 agattgccga gattctgggc ttggatgccg ctgctgccga acctatggtt gcggtggtga
      181 gatgtaatgg aacttgtgcc aaccgtcctc gtgtgaacca atacgatggc gccaagagtt
      241 gtgccattgc ggcttctctc tatggtggtg aaacgggttg tagttatggc tgtctgggat
      301 gcggcgactg tgtggctgcc tgccagttcg atgctatcca catgaatccg gagaccggac
      361 ttcccgaagt ggatgaggaa aagtgtacgg cttgtggagc ttgtgccaag gcttgtccga
      421 aatctattat tgaaatccgt cctcaaggca agaaatcacg tcgtatttac gtacagtgtg
      481 taaacaagga caagggggcc gtagcacgca aggcttgtac cgtggcatgt atcggttgcg
      541 gcaagtgtgt gaaggtttgt ccgttcgagg ctatcacgct ggaaaacaat ctggcttaca
      601 ttgaccccaa taagtgtaaa tcctgtcgca agtgcgagga agcttgtccg caaaacacaa
      661 tcattgccct caacttcccg ccgcgcaaac cgaaggctga cgatacagct ccccaagtaa
      721 aggttgcagt tcctaaagct gaggttgaga ctcctaaagc agaggtttag acttcccaag
      781 ttgaggtatg aattaataaa gtaaataaac gactaaaaat acagaattgt atgttgaaga
      841 cattttcaat tggtggagtc catccacacg aaaataaact ttcagcacat cagcctatca
      901 tcaaggcaga gattccggcc aaggccgcta tcttgctggg acagcacatc ggtgctcctg
      961 ccaagcctat cgttgccaaa ggtgatgttg tgaaagtggg tacaaagatt gccgagcccg
     1021 gcggttttgt atcagcagcc attcattcgt ctgtcagcgg gaaagtcgct aagattgaca
     1081 cgattgtcga tgccagcggt tacgccaagc ctgctatatt cattgacgta gaaggggatg
     1141 aatgggaaga atccattgac cgttccgaaa cgttggtgaa ggaatgcagt ctgacctccg
     1201 aggaaatcgt gaagaaaatc gctgatgccg gtatcgtagg tctgggcggt gcatgcttcc
     1261 ctacgcaggt caagttgtgt cctcctcctg cattcaaggc agagtgtgtc atcatcaacg
     1321 ccgtagagtg cgaaccgtat ctgactgccg accatcagct gatgctggaa catgcggaag
     1381 aaattatggt aggtgtatcc attctgatga aggcggtaaa ggtgaacaag gcattcatcg
     1441 gcattgagaa caataagccc gatgccatcc agctgatgac gaaggttgct tccagctatg
     1501 caggtatcga ggtggtaccc ttgaaggtac aatatccgca gggtggtgaa aagcagttga
     1561 ttgatgctgt catcagtcgc caggttgcag ccggtgcgtt gcctatctcc acgggagctg
     1621 tggtgcagaa tgtgggtacc gcatttgccg tttaccaggc cgtacagaag aacaaacctc
     1681 tgtttgagcg tgtcattacc gtgaccggta agtcgttggc aaagccgtcc aatttcctgg
     1741 cacgtatcgg tacgccgatg aagcagctga ttgaagcttg cggcggtttg cccgaagata
     1801 cgggtaagat tatcggcggt ggcccgatga tgggtaaagc tctggtaaat acggatgtac
     1861 cgacagccaa aggaagctcc ggtattctga ttatgaacga gaaggaagcc aagcgcggcg
     1921 aagtacagcc ttgtatccgt tgtgccaagt gcgtgggagc ctgcccgatg gggttggagc
     1981 cgtatctgct ggctaccgtt tcggcccacg gagattttga aagagtagag aaagaagaca
     2041 ttatgtcgtg tatagaatgc ggttcatgcc agttcacttg tccttccaac cgtccgatgc
     2101 tggattatat ccgcttgggt aagggtaagg taggagcgat gatccgtgca cgtcaagcta
     2161 aaaaataacg aagtatgaat aaattaatcg tatccctttc gccccacgtt cacggcggtg
     2221 acagcgtgaa gaagaatatg tacggtgtgc ttatcgcatt gattccggca ttcctcgttt
     2281 cgctttactt tttcggactg ggtgcgctga ttgttacggc aacttccgta gcagcctgct
     2341 tgttctttga atgggccatc ggcaaattcc tcatgaaaaa agagaccaca accatcaccg
     2401 acggctctgc catcattacc ggtgtgttgc tggcctttaa cctgccttcc aacctgccca
     2461 tctggattat catccttggt gccttgtttg ccatcggggt aggcaagatg tccttcggag
     2521 gtttgggttg caatcccttt aaccctgcac tggcaggacg tgtattcctg ttgctttcat
     2581 tccccgtgca gatgacgaca tggccggctg taggccagtt gacagcctat acggatgcca
     2641 cgacggctgc tacgccgctg gctattatga aaggtgtcat caatggtgct ccgggcatgt
     2701 ccctgagcga ccttccggga gctttcgacc ttctgatagg taataatgga ggatgtctcg
     2761 gtgaggtgag tgctttggcg ctgctgcttg gtttgttcta catgttgtgg aagaaaatca
     2821 tcacctggca cattccggta tctattctgg tgacggtatt cgtgttctcc ggtatcatgt
     2881 atctggtcaa tccggaactt tatgtatccc cggtcgtaca gttgttgtcc ggtggtctga
     2941 tgctgggtgc tgtctttatg gctacggact acgtgacttc tccgatgagc cacaaaggta
     3001 tgctgattta tggtgtttgc atcggcctac tgactgtcat catccgtctg ttcggtgcat
     3061 atccggaggg tatgtcgttt gccattctga ttatgaatgc gttcactccg ctcatcaaca
     3121 cctatgttaa acctaaacgc tttggggagg tagcgaagaa gaaatgaaaa agttagaatc
     3181 atccttgaag aatatgttgc tggtacttac gggcgttacc gcaatctccg tagcgttgct
     3241 ggcttatgta aacgaattga cgaaggagcc cattgcgcag gccaatgcaa agaccttgag
     3301 cgatgccgta agtgcggtgg ttccgggctt cgacaatgac cccattgccg agaagaagat
     3361 gcaggaagta aacggagtac agtattctgt atatcctgcc accaaaggtg gagaatatat
     3421 cggagctgct gtggaagctg ttgccatggg ttttggcggt gagctgaaag tgttggtcgg
     3481 tttcgatgct gaaggcaaaa tcatcgacta ctccttgttg tcgcatgtgg aaactccggg
     3541 gttgggttcc aaggctgccg actggttcaa gaaaggcaat aaaggtgaca tcaccggcat
     3601 gaatccgggt gaagctgcat tgacagtgag caaggacggt ggtaaagtag atgccattac
     3661 agcgtctacc atcacctcac gtgctttttt gaatgcagtg aatgcggctt atgctgccta
     3721 tgccggtcag gaaactgccg acggcactac cggcgctact caaaagaatg ttgaacaacc
     3781 tgctgattcc gcagctcccg aagctgtgga tacactcagc gctaaataag aaaggagtag
     3841 aagatatgaa taattttaaa gttatgatga acgggattat caaagagaat cctacgtttg
     3901 tactcctgct gggtatgtgt cctacactgg gtaccacttc ctctgccatt aacggtatgg
     3961 gtatgggact ggctacaatg ttcgtgctga tatgttccaa tgtggtgatt tctgccatca
     4021 agaatctgat tcccgatatg gtgcgtatcc cttcattcat tgtagtcata gcatcatttg
     4081 tgacactgtt gcagatgata atgcaagctt acgttcctgc attgtacgcc acactgggcc
     4141 tgttcattcc gctgattgtt gtaaactgta tcgtattggg acgtgccgag gcatttgctg
     4201 ccaaaaacaa tccggtggct tccttgttcg acggtctggg catgggcttg ggctttacca
     4261 ttgcactgac attactgggt gccgtgcgtg agttcctggg aaccggcaag atattcaact
     4321 tgagtatcct tcctgaagaa tacggcatgt tggtatttgt ccttgctccg ggtgcattca
     4381 tcgcattggg ctatctcatt gctttaatca acagtatgaa gaagaattaa taatgaaaaa
     4441 ttaaaaatga aaaaattgag aacgtatcgg cggtaggctg ccgggctttt aatttttagt
     4501 ttttaattct taatttaatg attatggaat atatattgat atttatctcg gcaatctttg
     4561 taaacaacat cgtattgtcg caattcttgg gaatttgccc gttcttggga gtttccaaga
     4621 aagtggagac tgcattgggc atgtcggcag cggtggcatt cgtgctcacc atcgccacta
     4681 tcgtgacatt ccttattcag aagtatgtgc tcgacgcttt tgatttgggc tatttgcaga
     4741 ctattacctt tatcttggtg attgccgcat tggtgcagat ggtagagatt atcctgaaga
     4801 aagtttctcc ttctctgtat caggccttgg gcgtgttcct gccgttgatt actaccaact
     4861 gctgtattct cggtgtggct atccttgtta tccaaaaaga ttatgatttg ctgacgggag
     4921 tggtttatgc attctccacg gcacttggtt tcggcttggc actgacactg tttgcaggcc
     4981 tgcgcgagca aatgagcctg gttagtgtac cgaaaggtat gcagggtact ccgatagctt
     5041 tgattactgc cggactgctg gcaatggcat tcatgggctt ttcgggggtt gtgaagattt
     5101 aaagaagaaa aaacggaaat aaagtggaag ggggataaac taaaatttat cccccttttt
     5161 ctgtttttat taatttattt ccttacattt gtggcgtatt gataacctaa aagctaaatt
     5221 atctatattt aatatgaaag ggaaaatctt agttacgggt ggaaccggtt atattggttc
     5281 tcacacggtg gtggaacttc aaaacgcagg ttatgaagtt gttattattg ataatttgtc
     5341 aaactccagc gcagatgttg tagataacat agagaaggta tcgggcatcc gccctgcatt
     5401 cgaggaattg gattgcttgg attatgccgg tcttgacgct gtgtttacca aatataaagg
     5461 cattaaagcc atcattcact ttgcggccag caaggctgtg ggtgaatctg tccagaaacc
     5521 gttgctttac tatcgtaata acctggtttc actgataaac ctgctggaat tgatgccgaa
     5581 gcatggagtg gaaggtatcg tattctcttc ttcctgcaca gtttacggcc agccggacga
     5641 acttccggta acggaaaagg cacctattaa gaaagctgag tctccgtatg gaaacacgaa
     5701 gcaaatcaat gaagagattg tacgtgatac ggttgcttcc ggtgctccga taaacgccat
     5761 cttgttgcgt tacttcaacc cgataggtgc acaccccaca gcattgctgg gagagttgcc
     5821 taacggtgta ccgcagaact tgattcctta tcttacccag accgctatcg gcatccgtga
     5881 gaaactgagc gtgtttggtg acgattatga tactcccgac ggttcttgta tccgcgactt
     5941 catcaatgta gtcgatttgg ccaaagcaca cgtagtggct atccgccgta tcttggagaa
     6001 caagcagaag gaaaaagtgg aagtattcaa tatcggtaca ggtcgtggac tttccgtatt
     6061 ggaactgatt aatgctttcg aaaaggctac cggtgtaaaa ctgaactatc agatagtagg
     6121 tcggcgtgcc ggtgatattg agaaggtatg ggcaaacccg gaattggcaa acaatgaact
     6181 gggttggaag gcagaaacaa gtattgaaga tactttactt tctgcatgga aatggcagtt
     6241 gaagcttcgt gaaagaggta ttcaatgaca aactttgaat ttgtgttttt taacaaatag
     6301 gcaataaaca aatgcctccc cgcatttgtt tataatgtgc aaatcagcct gaagctgttt
     6361 atgtatatgt gaatatccgt aactagtacg tatgcctccc cggcatagac aggtaagatt
     6421 gcatagtagt tttgtcgtgt tttattttgt gtttgtgttg tgaataagcc ttgtcgagag
     6481 acaaggctta ttttttgtat attatataca gaatctctgt tgtcaattca gtgttttttc
     6541 ataagatggg taggcaattc ctttttctta ctaattgtta actgacgtta tcatgtctgt
     6601 aacaatttgt tccaattgta gtattaatcg ttcaaaatag tcttttttgt tcaaaaaatg
     6661 ctatacacgg taacaactac atgcaaattg tttatacatt tgcgttgttg tttatgtaac
     6721 tattgggatg aacaaaccat agctgacaaa cgttaatagg tacgagtaca tagctgatga
     6781 aagacgcgac ttggctgact tgttaatgag gatacacgcg acttacaact tagtattggg
     6841 aaaaataatt aaggaaatat agaataaaaa gattgcttat gtcacagatt gtcggacata
     6901 tctcacaggt aatcgggcct gtagtagacg tctatttcga aggtacggag gcagaaatga
     6961 tgttgccgag tattcacgac gcactggaaa taaaaaggtc gaacggcaaa agactgattg
     7021 tagaggtaca gcagcacatt ggtgaaaaca cggtgcgtac tgttgctatg gacagtacgg
     7081 acggcctgca gagaggaatg acagtgcatc cgctgggagg ccccatcacc atgccgatag
     7141 gtacacaaat caaaggccgc ctgatgaacg tagtgggcga ctctatcgac ggcatgaagg
     7201 agttggaccg tacaggtgct tatcccatcc atcgcgaccc ccctaagttt gaagatttga
     7261 ctaccgtaca agaggtgctt tatacaggca tcaaggttat cgacttgctg gaaccatata
     7321 gcaagggcgg taaaatcggt ctgtttggtg gcgccggtgt aggcaagacg gtgcttatcc
     7381 aagagctcat taataatatt gcgaagaagc agcacggctt ctctgtgttt gccggtgtag
     7441 gagaacgtac acgtgaaggc aacgacctgc tgagagaaat gattgaatcc ggcgttatcc
     7501 gttacggaga agaattcaag aaaggtatgg aggaaggcca ttgggatttg tccaaagtag
     7561 attatgacga agtggccaaa tcacaagtgt ctttgatatt cggtcagatg aacgaacctc
     7621 ccggtgcgcg tcagtccgtg gcattgtctg ggttgacggt ggccgagtcc ttccgtgaca
     7681 tgggagcgga gacagacggg ccgcgtgaca ttctgttctt cattgataat atcttccgtt
     7741 tcacccaagc cggttccgag gtttcggcct tgctgggccg tatgccttct gccgtgggct
     7801 atcagccgac actggcaacg gaaatgggtg ccatgcagga gcgtattacc tccacaagaa
     7861 acggctccat cacttccgtg caggctgtat atgtgcctgc cgatgacttg acagacccgg
     7921 cgcctgccac aacgtttacc cacctcgatg ccaccacggt gttgagtcgt aagattactg
     7981 aacttggtat ttatcctgct gtggacccgt tggaatctac ttcacgcatt ctcgacccac
     8041 acatcgtggg ggtagaacac tacgaagtgg cacaacgtgt aaaacaaata ttgcagcgca
     8101 acaaggaatt gcaagacatt atctccatcc ttggtatgga ggaactctct gatgccgacc
     8161 gtacgttggt gaaccgtgca cgtcgtgtgc agcgtttcct ttcacagccg tttgccgttg
     8221 ccgagcagtt tacgggtgtc ccaggtacaa tggtttccat tgaggacact atcaaaggct
     8281 tcaagatgat tcttgacgga gaggtggact acctgcccga acctgctttc ttgaatgtgg
     8341 gaaccattga agaagccatt gagaagggta agaaactact ggagcaggca gggggaaaaa
     8401 cgattaaaaa ttaaaagtct gggagctttg atgatgaaaa agttgcattt gaatattgtt
     8461 tcaccggaga aggaactctt caacggggaa gtggaaagtg ttacattgcc gggcactatg
     8521 ggctcttttt ctatcctgcc gcagcatgca ccgattgtat catcgttggg aacggggaaa
     8581 ttgatttacg caacggacgg tgaggaacat gagttggata ttcaaagcgg attcgtggag
     8641 atgagtaacg gaagggttgc cgtctgtata gaacagcaat aggctattaa aaaattaaaa
     8701 attaaaaaat agaggttgtt ggcgtgacta ttactaagag aaactactta ttgcatacag
     8761 cgctcttgac ggtattgata ggaattgtag gcggttgggc gtatttttcg ataaatccgc
     8821 atcactattt cggcggttat ccgctgattc cgcttttctt ctttgttttc ggagtattca
     8881 tgattaatat gaccgaaagc tgccgtcacc ggatgccagg acgaatgttg cagatttatc
     8941 tgctgatgcg tgtgatgaga atactggtct ccatgattgt gatgctggtt tattgcgttg
     9001 cagtacgtga ggaagccagg gcgtttttgt tgacgtttat agccaactat ctgatatatt
     9061 tgatttatga ttcctggttc ttcttcactt ttgaggcgaa tcggaaactg aaaaagaaaa
     9121 gtaacaatga aaagattgcg taacatactg actgtaattc tgctggcact gggcatgttg
     9181 ctacccgcca cggtgcgggc cgagaatacg gtggacgtga aggagattgt cttcgggcat
     9241 atcggcgatt cttacgaatg gcacatcacg acgtggggcg aaactcacgt tacgattccc
     9301 ttgccggtaa tagtgcatag ctctaccacc ggatggcatg cctttctatc ctcacgtctg
     9361 gaggagaacg gtggaagtta tgaaggcttt tccatcgctc ccgcaggaag caagtacgaa
     9421 ggcaagctgg tggagtatga tgccatcgga aacgaaatac gcccgttgga catctccatc
     9481 acgaaggtga cactggcttt gctcatcaac agcgcattgc tgcttgtcat cattttgagt
     9541 gtggcgcact ggtatcgcaa gcacccgcag ggaagtgccg ctcccggtgg tttcatcggg
     9601 tttatggaga tgtttatcat gatggtgaac gatgatatta taaagagctg tgtcggtccg
     9661 aagtaccgta aatttgcacc ttacttgttg acggccttct tctttatttt catcaacaac
     9721 attatggggc tgattccttt ctttcccgga ggggccaacg tgacgggaaa tatagccatt
     9781 acgatggtat tggccatctg tactttcttg gccgtgaata tctttggaac caagacctat
     9841 tggaaagata ttttttggcc ggatgtgccc tggtggctga aggtaccggt ccccatgatg
     9901 ccgtttatcg agttcttcgg tattttcacc aaaccgtttg ctttgatgat acgtcttttt
     9961 gccaatatgc tggcagggca catggcaatg ctggtgctta cctgcctaat attcatctcg
    10021 gccagtatgg gacctgcttt gaacggaacg ctgaccgtgg catcggtgtt gttcaatatc
    10081 tttatgaatg cacttgagtt gttggttgcc tttatccagg catatgtgtt caccatgctg
    10141 tcagccgtgt tcatcggtct ggcgcaggaa gagcataagg agaaggcggt gaagtgatac
    10201 gattattggg aatataaata ttaataaaaa taaccattta aaaactgaaa gttatgttac
    10261 tatctgtatt attgcaagct gctgcggcag gtgtgggagt tagtaaattg ggtgcagcca
    10321 ttggtgctgg tctggctgtt attggtgctg gtgcaggtat cggtaaaatc ggtagttctg
    10381 ccatggaagc cattgcccgt caaccggaag catccggaga tatccgtatg aacatgatta
    10441 ttgccgctgc cttgattgaa ggtgttgctt tgttggcagt agttgtgtgt ttattggtat
    10501 tctttttata atgtacaatc taccatttac catttacaat ttgtccgtgc agcatcaccg
    10561 cgcagccaaa ttgtaaatcg taaattgtca aatagtaaat aaaattatgt cattgttatt
    10621 acccgatagt ggtctgctgt tctggatgct cctttcattc ggtgtggtgt ttgtggtgct
    10681 tgccaagtac ggttttcccg ttatcaccaa gatggtggaa ggtcgcaaga cctacatcga
    10741 ccagtctttg gaagtggcac gcgaagcaaa tgcccagctc tccaaactga aagaggagag
    10801 tgaagcgttg attgctgctg ccaacaaaga acaaggacgt attctgcggg aggcgatgca
    10861 tgagcgtgac aagattatcg tcgaagcacg caagcaggcg gaagccgccg cgcagaagga
    10921 gctggacgaa gttaaaaagc agatacagca agagaaggaa gaggccatcc gcgatattcg
    10981 ccgccaggtg gcagtcttgt ccgtagatat agccgagaaa attatccgca agaatctgga
    11041 cgagaaacat gagcagatgg agatgataga ccggatgctg gatgaagtgc tggccgcaag
    11101 taaaaacaat taattctcaa agaaatggat ataggaatcg tttcgatgcg ttatgcgaaa
    11161 gcattgatgg aatatgccaa gagcatgggg gcagaagata ctctgtacaa ggagttttgt
    11221 atgctcgacc gtagcttcag gaaacatccc gatttgcgca tggcattgga aaaccccatc
    11281 ctgacgatac gtgagaagtt aacacttatc tgtaccgctg ctgtggggga tgctcctgcg
    11341 ggccgtgagt ttgcgcgttt catgaccctg gtgttgaaga accggcggga aaactttctc
    11401 cagtacatct gcctgagttt tctggatttg taccggaaag acaagcatat cggtgtagga
    11461 aagctgataa cagccgttcc cgtcagccag gaagtgcggg agcgcatcca tgacagtgct
    11521 tcctccctgc tgcatgccag catggagctg cagactgaag tggatccctc cattgaaggt
    11581 ggttttatct tcgacatcaa cgacttccgt ctggatgcca gtattgctac gcagcttaag
    11641 aaagtgaaac agcagttcat tgataagaat agaagaatcg tgtgatttac gatttgacaa
    11701 tttacaattt acttatttaa tagtcttgtg atgcgtaagt tgtagaggtc aaacagtata
    11761 tgattcgggt tctttcaaat agtaaatagt aaattgtaaa atagtaaata ctaagatgtt
    11821 gtctgaaaat ataaaagtaa gcgaagtctc cgatattctc cgcaagcaac tggaagggat
    11881 tgacacccgc gtacagttgg acgagattgg cacggtactg caagtcagtg acggtgtagc
    11941 ccgtatctat gggttgcgca atgccgaagc caacgagttg ttggagttcg acaacggcat
    12001 caaggccatt gtgatgaacc tcgaagagga taatgtgggt gctgtgttgc ttggccctac
    12061 ggataaaatc aaggaaggct tcattgtaaa gcgtaccaag cgtattgctt ccatcatggt
    12121 gggagagggt atgctgggcc gtgtaataga ccctctgggt gcgccgctcg atggcaaagg
    12181 actgataggc ggagaacttt atgaaatgcc gctggaacgc aaggcgccgg gagttatctt
    12241 ccgtcagccg gtgaatcagc cgctacagac cggtctgaag gctgtggatg ccatgatacc
    12301 tatcggccgt ggacagcgtg agctgattat cggtgaccgc cagaccggta agacggccat
    12361 tgccatcgat accatcatca accagcgtgc caattttgat gctggtgatc cggtatattg
    12421 catttatgta gccattggcc agaaaggttc taccgtagct tctattgtga ataccctgca
    12481 ccagtacggt gcgatggact ataccattgt ggtggctgct acggcgggag acccggctgc
    12541 attgcagtat tacgctccct ttgcaggggc tgccatcgga gagtatttcc gtgataccgg
    12601 ccgtcatgcg ctggtggtct atgacgactt gtccaagcag gcggtggcct atcgtgaagt
    12661 gtctctgatt ctgcgccgtc cgtcaggacg tgaggcctat ccgggtgata tcttctatct
    12721 gcactcccgt ttgttggaac gtgcggcgaa gattatcagc caggaggaag tggcacgcga
    12781 gatgaacgac ctgccggaca gtctgaaagg caaggtgaaa ggtggcggtt cgctgactgc
    12841 attgcccatt atcgaaactc aggcaggaga cgtgtccgcc tatatcccaa cgaatgtgat
    12901 ttcaatcact gacgggcaga tattccttga tacgaacctc ttcaaccagg gtaaccgtcc
    12961 ggccattgac gtgggtatct ctgtgagccg tgtgggtggt aatgcccaag tcaaggctat
    13021 gaagaaggtg gcaggtacat taaagattga ccaggcacag taccgggagc tggaagcgtt
    13081 taccaagttc agtggcgata tggaccccgt gacggcattg accatcgaca agggacagaa
    13141 gaatacacgc ctgctggtac agccccaata cagcccgatg ccggtagaaa agcagattgc
    13201 cattctttat tgcggcacgc acggcttgtt gaggaatgtt cctttggaca aggtcagcga
    13261 gtttgaacgc aacttccttg agtctcttga gatgaactat cgcatggagg tactcgacgt
    13321 tttaaagacg ggtgccatca atgacgatgt ctgcaagaag attgaggaga cggcagaggc
    13381 ggttgcaagg caattcatgt gatttacgat tggacgattt acgatttacg attggagtta
    13441 ctctatatgg taagttgtaa atcggacgca ggcagaagtt acctcaatcg taaatcgtaa
    13501 ataattaaat cgtaaataga tatatgtctt cactgaaaga ggtaaaaaat agaataagct
    13561 ccgtcaagag tacacgccag ataacatcgg ctatgaagat ggtggcatct gccaaactgc
    13621 ataaggcgca ggggcggatt gagaatatgc tgccttatca acggaagctg aatgagattc
    13681 tgacgaactt tctgcgtacg gatgcttcct tcgagtcgcc ctataccgag aaaagacccg
    13741 tgacgagggt agcggtcgtg gcgttttcgt ccaatagttc cttgtgcggt gcattcaact
    13801 cgaatgtggc gaagatgctg gaacgggctt tggaagatta ccagtcgctg ggcaaggaga
    13861 atattctgat atatcccgtt gggagaaagg tggaggaagc cgtcaagaaa atgggatatg
    13921 tgccgcaagg cagctaccag gtgatggcag acaagccttc gtacgttgaa gcgtatgagc
    13981 tggcagagaa gttgatgcat gagtttgtgg aaaagcagat tgaccatgtg gagctgattt
    14041 accatcactt caaatcgatg ggttcgcagg tgctgctccg cgagaattat ctgcccattg
    14101 acctgacgca agtagcgcag gaggcggcag aagatgtacc ggaggatgcc cgcagtttta
    14161 ataatgatta cattgtggaa ccttccgtcg gcgaactgat agcggaactt ctgccaaaag
    14221 tgttgagtca gaagatattt accgtgcttc tcgattccaa tacttcggaa catgctgccc
    14281 gtatgctagc catgcagacg gcgacagata atgccaacga gttgattcaa gatttgacga
    14341 aacagtataa caagagccgt cagcaggcca ttacgaatga gctgctcgat attatcggcg
    14401 gtagcttgaa atagtccgga ttgccccgta aagggctttc tcaggatggg tacaaataaa
    14461 tggaataata ggacaaggat aacgaaataa ccgctatctt tgtcctatta tcatatatga
    14521 ctactgatga aatccgtatc attctgagag agagcggatt ggttgaataa taaacatatc
    14581 aatggagaat aatcccgaaa tagcgcttgc atggcaattc attgaaaaca caggcactca
    14641 tctttttttg accggcaagg caggtaccgg taagacaact ttcctgcgaa aactgagggc
    14701 agagagtccg aaacggatga ttgtacttgc accgacggga attgccgcta tcaatgcagg
    14761 cggtgtcacc atccactcct ttttccaagt acctttcgct ccttatgtgc ccgaaagctc
    14821 attcagcgcg gatggcaaag catcttaccg tttccgttac gggaaagaga aaatcaacat
    14881 tatacgcagt atagatttat tggtcatcga tgaaatcagt atggtccgtg ccgacttgct
    14941 cgattcggtg gatgccgtct tgaggcggtt ccgcgaccgg aacaaaccct ttggcggcgt
    15001 gcaactgctg atgattggcg accttcagca gcttgctccc gtagtgaaag acgatgagtg
    15061 gcagatgctg cgtaaatact atgacacgcc ttatttcttc tc
//
