LOCUS       c00063_gnlPro..        13285 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|JJLNGNPP_63.
ACCESSION   c00063_gnlPro..
VERSION     c00063_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-05 13:24:28
            Original ID  :: gnl|Prokka|JJLNGNPP_63
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 13285
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             complement(1..978)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: NQR2_RnfD_RnfE"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg63_1"
                     /sec_met_domain="NQR2_RnfD_RnfE (E-value: 1.8e-119,
                     bitscore: 388.0, seeds: 472, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNKLIVSLSPHVHGGDSVKKNMYGVLIALIPAFLVSLYFFGLGAL
                     IVTATSVAACLFFEWAIGKFLMKKETTTITDGSAIITGVLLAFNLPSNLPIWIIILGAL
                     FAIGVGKMSFGGLGCNPFNPALAGRVFLLLSFPVQMTTWPAVGQLTAYTDATTAATPLA
                     IMKGVINGAPGMSLSDLPGAFDLLIGNNGGCLGEVSALALLLGLFYMLWKKIITWHIPV
                     SILVTVFVFSGIMYLVNPELYVSPVVQLLSGGLMLGAVFMATDYVTSPMSHKGMLIYGV
                     CIGLLTVIIRLFGAYPEGMSFAILIMNAFTPLINTYVKPKRFGEV"
     protocluster    1..13285
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[0:3285]"
                     /cutoff="2000"
                     /detection_rule="(Complex1_51K and minimum(5, [FMN_bind,
                     FeS, Fer4, Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N,
                     SLBB]))"
                     /neighbourhood="10000"
                     /product="Rnf_complex"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      1..3285
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="(Complex1_51K and minimum(5, [FMN_bind,
                     FeS, Fer4, Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N,
                     SLBB]))"
                     /neighbourhood="10000"
                     /product="Rnf_complex"
                     /protocluster_number="1"
     cand_cluster    1..13285
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Complex1_51K and minimum(5, [FMN_bind,
                     FeS, Fer4, Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N,
                     SLBB]))"
                     /kind="single"
                     /product="Rnf_complex"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..13285
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Rnf_complex"
                     /region_number="1"
                     /rules="(Complex1_51K and minimum(5, [FMN_bind, FeS, Fer4,
                     Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N, SLBB]))"
                     /tool="gutsmash"
     CDS             complement(985..2322)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: SLBB"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: RnfC_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Complex1_51K"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_10"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg63_2"
                     /sec_met_domain="Fer4_10 (E-value: 1.7e-09, bitscore: 27.3,
                     seeds: 59, tool: rule-based-clusters)"
                     /sec_met_domain="SLBB (E-value: 3.6e-16, bitscore: 48.5,
                     seeds: 67, tool: rule-based-clusters)"
                     /sec_met_domain="Complex1_51K (E-value: 9.3e-50, bitscore:
                     158.1, seeds: 88, tool: rule-based-clusters)"
                     /sec_met_domain="RnfC_N (E-value: 4.2e-30, bitscore: 93.4,
                     seeds: 53, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 3.3e-05, bitscore: 14.0,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLKTFSIGGVHPHENKLSAHQPIIKAEIPAKAAILLGQHIGAPAK
                     PIVAKGDVVKVGTKIAEPGGFVSAAIHSSVSGKVAKIDTIVDASGYAKPAIFIDVEGDE
                     WEESIDRSETLVKECSLTSEEIVKKIADAGIVGLGGACFPTQVKLCPPPAFKAECVIIN
                     AVECEPYLTADHQLMLEHAEEIMVGVSILMKAVKVNKAFIGIENNKPDAIQLMTKVASS
                     YAGIEVVPLKVQYPQGGEKQLIDAVISRQVTAGALPISTGAVVQNVGTAFAVYQAVQKN
                     KPLFERVITVTGKSLAKPSNFLARIGTPMKQLIEACGGLPEDTGKIIGGGPMMGKALVN
                     TDVPTAKGSSGILIMNEKEAKRGEVQPCIRCAKCVGACPMGLEPYLLATVSAHGDFERV
                     EKEDIMSCIECGSCQFTCPSNRPMLDYIRLGKGKVGAMIRARQAKK"
     CDS             complement(2383..3285)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: FeS"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Fer4"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_7"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_6"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1016:4Fe-4S dicluster domain (Score: 37.6; E-value:
                     8.3e-12)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg63_3"
                     /sec_met_domain="Fer4_7 (E-value: 1.5e-12, bitscore: 37.6,
                     seeds: 208, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4 (E-value: 8.3e-10, bitscore: 27.9,
                     seeds: 528, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_2 (E-value: 4.5e-09, bitscore: 25.8,
                     seeds: 214, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_6 (E-value: 4.7e-09, bitscore: 25.8,
                     seeds: 134, tool: rule-based-clusters)"
                     /sec_met_domain="FeS (E-value: 1e-11, bitscore: 34.0,
                     seeds: 364, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 5.3e-06, bitscore: 16.5,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNVILIAVISLGVIALVSAAILYVASKKFAVYEDPRIAQVAEVLP
                     QANCGGCGYPGCSGFADACVKAGSLDGKLCPVGGQPVMTKIAEILGLDAAAAEPMVAVV
                     RCNGTCANRPRVNQYDGAKSCAIAASLYGGETGCGYGCLGCGDCVAACQFDAIHMNPET
                     GLPEVDEEKCTACGACAKACPKSIIEIRPQGKKSRRVYVQCVNKDKGAVARKACTVACI
                     GCGKCVKVCPFEAITLENNLAYIDPNKCKSCRKCEEACPQNTIIALNFPPRKPKADDAA
                     PQVKVAAPKAEVETPKAEV"
     CDS             complement(3323..3742)
                     /locus_tag="ctg63_4"
                     /transl_table=11
                     /translation="MANTIKHQGIVENINGSHLQVRIIQTSACASCSVKGHCTSADTKE
                     KLVDVADADAASYQPGDRVWVTGELSMGVMAVLFAFIFPFLILIISLFVFMAIWNDELR
                     SALCSLALLVPYYYILWLNKSRMGKKFSFSVRPMN"
     CDS             complement(3973..5373)
                     /locus_tag="ctg63_5"
                     /transl_table=11
                     /translation="MISSSVMAQNTLDTASKNSGQETTAKADTLPDIMKEYMILKLKPE
                     GMGYRLDTVSILYERYIGVLDYLNDPTTPERYIPSNPNYYRLFLPLTYYYAPMRRLSKV
                     DWHFQVPDTVPALTREMLPFDTLSFTSKDRANKLVDRTLLNTYVNCPNLVVMTEKEVMK
                     GKIFKDNIEKEVSSKPSVVKLFAQENMVGVKEEADVIIHKPNWWVTGGNGSLQITQNYI
                     SDNWYKGGESTNAVLANLQLFANYNDREKVQWENLLDAKLGFSSAPSDEFHNYLVSTDQ
                     LRLYSKLGIQAASKWYYTITTEFKTQFCNGYKANSEELVSAFFAPADWSSSIGMDYKLK
                     KQKFSLSVFMAPLTYMLRYVGNKGVNEVSFGLDEGKCVKHNFGSQIQPTLSWTIIPSIT
                     LDSRLDFQTSYEWTRIEWENTVNFVLNRYLSTKLYVHARYDDSAKPTEGDSYFQVKELL
                     SFGINYKW"
     CDS             complement(5445..5651)
                     /locus_tag="ctg63_6"
                     /transl_table=11
                     /translation="MPRAYTACRSRCILLPSVHVELKKRKIIKKRGSRESFDETIIKKY
                     DFIEESPSCLFLMAFLCFLNILS"
     CDS             5683..7302
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GATase"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg63_7"
                     /sec_met_domain="GATase (E-value: 6.5e-55, bitscore: 175.4,
                     seeds: 97, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VGETKYIFVTGGVASSLGKGIISSSIGKLLQARGYKVTIQKFDPY
                     INIDPGTLNPYEHGECYVTVDGHEADLDLGHYERFLGIQTTKANNITTGRIYKSVIDKE
                     RRGDYLGKTIQVIPHITDEIKRNVKLLGNKYKFDFVITEIGGTVGDIESLPYLESIRQL
                     KWELGKDALCVHLTYVPYLAAAGELKTKPTQHSVKELQSAGIQPDVLVLRTEHELSTTL
                     RKKVALFCNVDENAVVQSIDAPTIYEVPILMQSQGLDVTILKKMGLPVGDTPGLGPWRA
                     FLERRHKAEETAPLHIALVGKYDLQDAYKSIREALSQAGTYNDRKVSVDFVNSEKLTDE
                     NVAEALKGMAGVLIGPGFGERGVAGKFVAIKYARTHDIPTFGICLGMQCIAIEFARNVL
                     GYADANSREMDEKTPHNVIDIMEEQKSITNMGGTMRLGAYECVLQKGSKAYEAYGTEHI
                     QERHRHRYEFNNSFKDAYEAAGMKCVGINPESDLVEIVEIPALKWFVGTQFHPEYSSTV
                     LHPHPLFVAFVKAAIENENEKK"
     CDS             7334..9187
                     /locus_tag="ctg63_8"
                     /transl_table=11
                     /translation="MDKNTITGLVLIAILLVGFSFLSRPSQEQLEAQQRYYDSIAQVQQ
                     READLKAKAEAALANESGAEASVDSTALFFDARQGTNSQVTIQNNLAEITVDTKGGRIA
                     SATLKEYMGQDKTTPVTLFSGNDASMNFLFYNKKETIQTEDYYFTAVNRTDSTVTMRLS
                     ADSNSYIDFTYSMHNDTYLIDFTIQAVNMEGKLAATNNYVDIEWSQRARQIEKGYTYEN
                     RLAELTYKITGEGTDYLSANKNDEKEVPERLDWIAFKNQFFSSVFLADADFEKTKLSSK
                     METQGSGYIKDYSAEMSTKFDPAGKEPTQLFFYFGPNHYKTLTALDKGRDDKWELNRLV
                     YLGWPLIRWINKWFTINIFDWLSSWGLSMGIVLLFMTLIVKAVVFPATWKTYMSSAKMR
                     VLKPKIDEINKKYPKQEDAMKKQQEVMGLYSQYGVSPMGGCLPMLIQFPILMALFMFVP
                     SAIELRQQSFLWADDLSTYDAFINFPFHIPFLGSHLSLFCLLMTVTNILNTKYMMQQQD
                     TGANPQMAAMKWMSYLMPVMFLFILNDYPSGLNYYYFISTLVSVVTTLIMRKTTNEEAL
                     LAQLEANKKDPKKMKKTGFAARLEAMQKQQEQMMKEKQNKK"
     CDS             9290..10621
                     /locus_tag="ctg63_9"
                     /transl_table=11
                     /translation="MQTKYTYKQIWLIAYPILISLLMEQMIGMTDTAFLGRVGEVELGA
                     SAIAGVFYMVIFMVAFGFSIGAQILIARRNGERQYKEIGDLFYQGIYFQVGMAAVMFLL
                     SYCFSPIILKRIVASEHIYEAATSYLHWRVFGAFFSFSAVMFRAFFLGTTQTKTLTLNS
                     IVMVLSNVVFNYILIFGKFGFPALGIAGAAIGSSLAELVSLLFFILYTRSRIDCCKYGL
                     DRIPKFRLDVLKRMLNVSFWTMIQNFFSLSTWFLFFLYVEHLGERSLAVTNIVRNVSGI
                     LFMVLMAFASTCGSLVSNLIGAGHSDCVAGTIRQHVRIAYVFVLPLALLFALFPKLILG
                     IYTDIPDLQDAAVHSLWVMCSTYLFLVPANVYFQAVSGTGNTRTALGMELATLVIYTAY
                     ITYIILILQLDVAICWTSEMVYSSFILIFCWLYIKRGNWQGRKI"
     CDS             10683..12782
                     /locus_tag="ctg63_10"
                     /transl_table=11
                     /translation="MSAAMTLASCGGTKDAGQQQDAAVLIQRSDIKIEGKRMTPEALWA
                     MGRIGSVAVSPDEKQIAYTVSYYSVPQNKSNSEVFVMNADGSGNTQITHDAWQEGQPTW
                     FKDGKKLAFLCNESGSSQVWEMNPDGSGRKQLTQYEGDIEGFSFSPDGKKLLFIAQVKT
                     VKSTADKHPDLPKATGIIVTDLMYKHWDEWVTTAPHPFVADFDGNAISNVTDILEGEPY
                     ESPMKPWGGIEQLAWSPSSDKVAYTCRKKTGLAYAISTNSDIYIYDLASKETKNITEEN
                     KGYDTNPQYSPDGKYIAWQSMERDGYEADLNRLFIMNLETGEKRFVSKAFESNVDAFLW
                     NKDSRSIYFIGVWHGETQIYNIDLAGNDKLTQLTDGMYDYASLALCGDKIIAKRHSMSM
                     GDEIYAVNSARNGDAFAEAVQLTTENKQIYDQLEMGKVEARWMKTTDGKQMLTWVIYPP
                     QFDPNKKYPTLLFCEGGPQSPVSQFWSYRWNFQIMAANDYIIVAPNRRGLPGFGVEWNE
                     AISGDYGGQCMKDYFTAIDEMAKEPFVDKDRLGCVGASFGGFSVYWLAGHHDKRFKAFI
                     AHDGIFNMEMQYLETEEKWFANWDMGGAYWEKNNATAQRTFANSPHLFVDKWDTPILCI
                     HGEKDFRILANQAMAAFDAAVMRGVPAELLIYPDENHWVLKPQNGVLWQRTFFEWLDKW
                     LKPAK"
ORIGIN
        1 tacctcccca aagcgtttag gtttaacata ggtgttgatg agcggagtga acgcattcat
       61 aatcagaatg gcaaacgaca taccctccgg atatgcaccg aacagacgga tgatgacagt
      121 cagtaggccg atgcaaacac cataaatcag catacctttg tggctcatcg gagaagtcac
      181 gtagtccgta gccataaaga cagcacccag catcagacca ccggacaaca actgtacgac
      241 cggggataca taaagttccg gattgaccag atacatgata ccggagaaca cgaataccgt
      301 caccagaata gataccggaa tgtgccaggt gatgattttc ttccacaaca tgtagaacaa
      361 accaagcagc agcgccaagg cactcacctc accgagacat cctccattat tacctatcag
      421 aaggtcgaaa gctcccggaa ggtcgctcag ggacatgccc ggagcaccat tgatgacacc
      481 tttcataata gccagcggcg tagcagctgt cgtggcatcc gtataggctg tcaactggcc
      541 tacagccggc catgtcgtca tctgcacggg gaatgaaagc aacaggaaca cacgtcctgc
      601 cagtgcaggg ttaaagggat tgcaacccaa acctccgaag gacatcttgc ctaccccgat
      661 ggcaaacaag gcaccaagga tgataatcca gatgggcagg ttggaaggca ggttaaaggc
      721 cagcaacaca ccggtaatga tggcagaacc gtcggtaatg gttgtggtct cttttttcat
      781 gaggaatttg ccgatggccc attcaaagaa caagcaggct gctacggaag tggccgtaac
      841 aatcagcgca cccagtccga aaaagtaaag cgaaacaagg aatgccggaa tcaatgcgat
      901 aagcacaccg tacatattct tcttcacgct gtcaccgccg tgaacgtggg gcgaaaggga
      961 tacgattaat ttattcatac ttcgttattt tttagcttga cgtgcacgga tcatcgctcc
     1021 taccttaccc ttacccaagc ggatataatc cagcatcgga cggttggaag gacaagtgaa
     1081 ctggcatgaa ccgcattcta tacacgacat aatgtcttct ttctctactc tttcaaaatc
     1141 tccgtgggcc gaaacggtag ccagcagata cggctccaac cccatcgggc aggctcccac
     1201 gcacttagca caacggatac aaggctgtac ttcgccgcgc ttggcttcct tctcgttcat
     1261 aatcagaata ccggagcttc ctttggctgt cggtacatcc gtatttacca gagctttacc
     1321 catcatcggg ccaccgccga taatcttgcc cgtatcttcg ggcagaccgc cgcaagcttc
     1381 aatcagctgc ttcatcggcg taccgatacg tgccaggaaa ttggacggct ttgccaacga
     1441 cttaccagtc acggtaatga cacgctcaaa cagaggtttg ttcttctgta cggcctggta
     1501 aacggcaaat gcggtaccca cattctgcac cacagctccc gtggagatag gcagcgcacc
     1561 ggctgtaacc tggcgactga tgacagcatc aatcaactgc ttttcaccac cctgcggata
     1621 ttgtaccttc aagggtacca cctcgatacc tgcatagctg gaagcaacct tcgtcatcag
     1681 ctggatggca tcgggcttgt tgttctcaat gccaatgaat gccttgttca cctttaccgc
     1741 tttcatcaga atggatacac ctaccataat ttcttccgca tgttccagca tcagctgatg
     1801 gtcggcagtc agatacggtt cgcactctac ggcgttgatg atgacacact ctgccttgaa
     1861 tgcaggagga ggacacaact tgacctgcgt aggaaagcat gcaccgccca gacctacgat
     1921 accggcatca gcgattttct tcacgatttc ctcggaggtc agactgcatt ccttcaccaa
     1981 cgtttcggaa cggtcaatgg attcttccca ttcatcccct tctacgtcaa tgaatatagc
     2041 aggcttggcg taaccgctgg catcgacaat cgtgtcaatc ttagcgactt tcccgctgac
     2101 agacgaatga atggctgctg atacaaaacc gccgggctcg gcaatcttcg tacccacttt
     2161 cacaacatca cctttggcaa cgataggctt ggcaggagca ccgatgtgct gtcccagcaa
     2221 gatagcggcc ttggccggaa tctctgcctt gatgataggc tgatgtgctg aaagtttatt
     2281 ttcgtgtgga tggactccac caattgaaaa tgtcttcaac atacaattct gtatttttag
     2341 tcgtttattt actttattaa ttcatacctc aacttgggaa gtctaaacct ctgctttggg
     2401 agtctcaacc tcagctttag gagctgcaac ctttacttgg ggagctgcat cgtcagcctt
     2461 cggtttgcgc ggcgggaagt tgagggcaat gattgtgttt tgcggacaag cttcctcgca
     2521 cttgcgacag gatttgcact tattggggtc aatgtaagcc agattgtttt ccagcgtgat
     2581 agcctcgaac ggacaaacct tcacacactt gccgcaaccg atacatgcca cggtacaagc
     2641 cttgcgtgct acagccccct tgtccttgtt tacacactgt acgtaaacac gacgtgattt
     2701 cttgccttga ggacggattt caatgataga tttcggacaa gccttggcac aagctccaca
     2761 agccgtacac ttttcctcat ccacttcggg aagtccggtc tccggattca tgtggatagc
     2821 atcgaactgg caggcagcca cacagtcgcc gcatcccaga cagccataac cacaacccgt
     2881 ttcaccacca tagagagaag ccgcaatggc acaactcttg gcgccatcgt attggttcac
     2941 acgaggacgg ttggcacaag ttccattaca tctcaccacc gcaaccatag gttcggcagc
     3001 agcggcatcc aagcccagaa tctcggcaat ctttgtcatg acgggctgtc cacccaccgg
     3061 acaaagttta ccatccagcg aacctgcctt tacgcaagca tctgcaaatc cgctacaacc
     3121 ggggtaacca catccaccgc aatttgcctg gggaagcacc tctgctacct gggcaatccg
     3181 cggatcttca tacacggcga atttcttgga agccacgtaa agaatagcgg ccgataccag
     3241 cgctataact cccaatgaaa tcactgcaat cagaattaca ttcataaatt agttgtttat
     3301 taattatttg ttttattatt agttagttca tcggtcgtac ggagaatgag aacttcttac
     3361 ccatccgcga cttgttcagc cacaatatat aataataagg tacaagaagt gctagcgaac
     3421 aaagcgcgga acgcagctcg tcattccaga tagccataaa gacaaacagt gagattatca
     3481 gaataaggaa aggaaatata aaggcaaaca gaactgccat cactcccatt gaaagttcgc
     3541 ccgtcaccca tacacggtcg ccgggctggt aggatgcggc atcggcatcg gccacatcga
     3601 caagtttctc tttcgtatcc gcagaggtac aatgtccctt gacactacac gaagcgcatg
     3661 ctgaagtctg gatgattctc acttggagat gagaaccgtt tatgttttcc acaatacctt
     3721 gatgttttat agtattcgcc attttgcaaa gtgtgcatta caaatcgtgg caaatttacg
     3781 cattatttgt gaactgcaaa cctttcctat gtattttctg tgttcgcaaa catgcttttt
     3841 ctatgttttt atgttttttc acctgccaca gactacaaaa agacaaaaaa cagacggtct
     3901 gtcaagggaa aacagaccgt ctgactaact aaaacagata atctgttcac tccgaacaga
     3961 ccatttgttt atttaccatt tataattgat accgaaactg agcaattctt ttacctgaaa
     4021 atagctgtcc ccttccgtcg gcttggcact gtcgtcatag cgggcgtgca catagagctt
     4081 ggtggaaaga tagcggttca gcacaaagtt caccgtgttt tcccattcaa tacgtgtcca
     4141 ctcataactg gtctggaagt ccaagcggga atccagcgtg atggaaggaa tgatggtcca
     4201 tgaaagtgta ggctgtatct gcgaaccgaa gttatgcttc acgcatttgc cctcatcaag
     4261 accgaaactc acttcattca cccccttatt tcctacatag cgcagcatgt acgtcagcgg
     4321 agccatgaaa acggacaagc tgaatttctg cttcttcaac ttgtagtcca taccgatact
     4381 gctcgaccag tctgccggag caaagaaagc cgaaaccagc tcttcactgt tggccttgta
     4441 gccattgcag aactgggtct taaactcagt cgtgatggta taataccact tggacgcagc
     4501 ctgaataccc agtttactgt acagccggag ttggtcggta cttaccagat agttatgaaa
     4561 ctcgtcggaa ggtgcggagc tgaagcccag cttggcatcg agcagatttt cccactgcac
     4621 cttttcacgg tcattatagt tggcaaacaa ttgcaggttg gcaagcacgg cgttagtgct
     4681 ctcacctccc ttgtaccagt tgtcggagat atagttctgg gtaatctgca atgaaccgtt
     4741 tccacccgtc acccaccagt tgggcttgtg gataatcacg tcggcttcct ccttcactcc
     4801 caccatattc tcttgtgcaa acagtttcac gacggacggc ttggaagaaa cctccttctc
     4861 tatattatcc ttgaatatct tccctttcat cacctccttc tcggtcatta caaccagatt
     4921 gggacaattc acatacgtgt tcagcagcgt acggtccacc agtttgttgg ctcggtcctt
     4981 tgaggtgaaa ctcagtgtgt cgaacggcaa catctcgcgc gtcagggcag gcaccgtatc
     5041 aggcacctgg aaatgccagt ccaccttgga aaggcgtctc atgggggcat aataataggt
     5101 aaggggaagg aacaacctat agtagttcgg attggaaggt atataacgct ccggagtcgt
     5161 ggggtcattc aaataatcca gcactccgat atacctttca tataatatgg aaacagtatc
     5221 cagcctgtac cccatacctt ccggtttcaa tttcagaatc atgtattctt tcattatatc
     5281 cggcaaggtg tcggctttgg cagttgtttc ctgtccactg ttcttcgagg cggtatccag
     5341 cgtattctgt gccatcaccg acgaagaaat catcgtagca attaaccaaa atgcaatgtg
     5401 tctattcttc ataatgccct aaagtctatg tttcgagcgc aaatttagct taaaatgttt
     5461 agaaaacata gaaaagccat aagaaaaagg caagaaggac tttcttcgat gaaatcgtat
     5521 tttttaataa ttgtttcatc gaaactttct ctacttcctc ttttttttat aattttgcgc
     5581 tttttaagtt ctacgtgtac tgacgggagc agtatgcacc ttgaacgaca agccgtatag
     5641 gctcttggca ttagattaaa caattaataa aataatatag ttgtgggaga aacaaagtat
     5701 attttcgtca ccggtggtgt tgcctcttca ttaggtaaag gtatcatctc atcctccatc
     5761 ggtaaattgc tgcaagcaag aggttacaag gtaaccatcc agaagtttga cccgtacatc
     5821 aacatcgacc cgggtacact gaacccttat gaacacggcg aatgctacgt taccgtggat
     5881 ggccacgaag ccgacctcga tttgggccat tacgaacgct tcctgggcat ccagaccacc
     5941 aaggccaaca atatcacgac cggacgcatc tacaaaagcg tcatcgacaa agagcgccgg
     6001 ggtgactatc tgggaaagac catccaggtt attccccata ttacagacga aatcaagcgt
     6061 aatgtaaaac tgctgggaaa caaatacaaa ttcgactttg ttattaccga gattggcggt
     6121 acagtgggtg acatcgagtc tctgccctat ctggaaagca tccgtcagct gaagtgggaa
     6181 ctgggaaaag acgccttgtg cgtacacctt acttatgtcc cctacctggc agctgccggt
     6241 gagctgaaga ccaagcccac ccagcactcc gtaaaggaac tgcaaagtgc cggtatccaa
     6301 cccgatgtcc tcgtactgcg tacggagcac gagttgagca ctaccctgcg caagaaggtg
     6361 gctctgttct gcaatgtgga cgagaatgcc gtggtgcaga gcatcgacgc gcctaccatc
     6421 tacgaggtgc ccatcttgat gcagagccag ggactggacg ttaccatttt gaagaaaatg
     6481 ggacttcccg tcggtgatac tccgggactg ggaccgtggc gtgctttcct cgaacgccgt
     6541 cacaaagccg aagagactgc cccactgcac atcgcattgg tgggcaaata tgacttgcag
     6601 gatgcctaca agtccatccg cgaggccctt tcacaagcag gaacctacaa tgaccgcaaa
     6661 gtatcggtag acttcgtgaa cagtgaaaag ctgactgacg agaatgtggc agaagccctg
     6721 aaaggcatgg caggcgtact tatcggtcca ggcttcggcg aacgcggcgt tgccggcaag
     6781 ttcgtagcca tcaaatatgc gcgtacgcac gacatcccca ccttcggtat ctgtctgggt
     6841 atgcagtgta tcgccatcga atttgcccgt aacgtactgg gttatgccga tgccaactca
     6901 cgcgagatgg acgaaaagac accgcacaat gtcatcgaca tcatggaaga gcagaagtcc
     6961 atcaccaata tgggtggaac catgcgtctg ggtgcctacg aatgtgttct gcagaaaggc
     7021 agcaaggcat acgaggcata tggtaccgag catatccagg aacgtcaccg tcaccgctac
     7081 gagttcaaca acagcttcaa ggatgcctac gaagcagcag gcatgaagtg tgtgggtata
     7141 aaccccgaat cggacctggt ggaaattgtt gagattcccg cattgaagtg gtttgtcggt
     7201 acccagttcc atcccgaata cagcagtacg gtattgcatc cgcacccact gttcgtagca
     7261 ttcgtgaagg ccgccatcga aaatgaaaac gaaaagaaat aatttgtaat aagtaatttg
     7321 taatcaacaa agaatggata aaaataccat cacaggtctt gttctgatag cgatattgtt
     7381 agtaggtttc agctttctga gccgtcccag ccaggagcag ttggaagcac agcaacgtta
     7441 ctacgactcc atagcccagg tgcaacagcg cgaagccgac ttgaaagcca aggcggaagc
     7501 agccctggcc aacgaaagcg gagcggaagc aagcgttgac tccactgccc tcttcttcga
     7561 cgcccgtcaa ggaaccaact cgcaggtaac catccagaac aacctggcag aaataaccgt
     7621 agatacaaaa ggcgggcgca tagcttcggc cacgctgaag gaatacatgg gacaagacaa
     7681 gacgaccccc gtcacactgt tcagcggcaa tgacgcctcc atgaatttcc tcttttacaa
     7741 caagaaagag actatccaga cggaagacta ttatttcacc gcagtaaacc gtacggacag
     7801 taccgtcacc atgcgtttgt cggcagacag caacagctat atcgacttta cctacagcat
     7861 gcacaatgac acatacctga tagactttac tatccaggca gtcaatatgg aaggcaagct
     7921 ggcggctacc aacaattatg tggacatcga gtggtctcag cgtgcccgtc agatagagaa
     7981 gggttacacc tacgagaacc gtctggctga actgacttac aaaatcaccg gagagggtac
     8041 cgattatctg tccgccaaca agaacgacga aaaggaagtt ccggaacgcc tggactggat
     8101 tgctttcaag aaccagttct tctcttcagt atttttggca gatgccgact ttgaaaagac
     8161 caaactgagt tccaagatgg agactcaagg cagcggctac atcaaggact attctgcgga
     8221 gatgagcacg aagttcgacc ctgccggcaa ggaacctacc cagctgttct tctacttcgg
     8281 ccccaatcac tacaagactc tgaccgcact cgacaaggga cgtgacgata agtgggagct
     8341 gaaccgtctg gtctatctgg gctggccgct catccgctgg ataaacaaat ggttcaccat
     8401 caacatcttc gactggttgt ccagttgggg tttgagcatg ggtatcgtac tgttgttcat
     8461 gacgctgatt gtaaaggcag tggtattccc ggctacgtgg aagacctaca tgtcttctgc
     8521 caagatgcgc gtactgaaac cgaaaatcga cgagataaac aagaagtacc ccaagcagga
     8581 agatgccatg aagaagcagc aggaagtgat gggcctctac agccagtacg gagtcagccc
     8641 gatgggcgga tgtctgccga tgctgataca gttccctatc ctgatggcct tgttcatgtt
     8701 cgtgccgagt gccattgaac tccgccaaca gagcttctta tgggcagacg acctttccac
     8761 ttatgatgcg ttcatcaact tcccgttcca tatcccgttc ctgggcagcc acctcagctt
     8821 gttctgcctg ctgatgacgg ttaccaacat attgaacacg aagtacatga tgcagcagca
     8881 ggatacgggt gccaatccgc agatggctgc catgaagtgg atgtcatacc tgatgcctgt
     8941 catgttcctc ttcatattga acgactatcc ttcgggattg aactattact acttcatctc
     9001 tacgttagtc agtgtggtaa caacgctcat catgcgcaag acaaccaatg aggaagccct
     9061 tcttgctcag ttggaagcca acaagaaaga cccgaagaag atgaagaaaa ccggtttcgc
     9121 cgctcgtctg gaagccatgc agaaacagca ggaacagatg atgaaagaaa aacagaacaa
     9181 aaagtagtaa gactaccgtt caagatattc ttttgcagaa agccggacaa tgacatttgc
     9241 ccggctttct tatccttaca ccaacgaaaa aattcacaga ctctaaatta tgcagactaa
     9301 atacacttac aaacaaatct ggctcatagc ctaccctatc ctaatcagcc tccttatgga
     9361 gcagatgata ggtatgacgg acaccgcctt cctcggacgt gtaggtgaag tcgagttggg
     9421 agcatctgcc atcgccggtg tcttctatat ggtcatcttc atggttgcct tcggtttcag
     9481 catcggggca cagatactca ttgcccggcg caacggcgaa cggcagtata aggaaatcgg
     9541 tgacttgttc tatcagggca tctatttcca agtcgggatg gcggcagtca tgttcctgct
     9601 atcttattgc ttctcgccga ttatcctgaa acgcatcgta gcctcggaac atatctacga
     9661 agcagccacc agctacctgc actggcgtgt attcggtgcc ttcttctcgt tcagcgcagt
     9721 catgttccgt gcctttttct tgggaaccac ccagaccaag acactgacac tgaactccat
     9781 cgtcatggtg ttgagcaatg tcgtattcaa ctatatcctg attttcggta aattcggttt
     9841 tcctgcactc ggcattgccg gagccgccat cggctcctca ttggccgagc tggtttcgct
     9901 gttattcttc atcctctata cccgtagccg tatcgactgc tgcaagtacg ggctggaccg
     9961 tattccgaag ttccggctgg acgtattgaa acggatgctg aacgtctctt tctggaccat
    10021 gatacagaat ttcttctccc tctccacctg gttcttgttc ttcctttatg tggagcatct
    10081 gggagagcga tcgctggcag tgaccaacat tgtccgcaat gtgtccggca tactgttcat
    10141 ggtactcatg gcatttgcct ctacctgcgg ttcattggtc agcaacctca tcggtgcagg
    10201 ccactccgat tgcgtggcag gcactatccg gcagcacgta cgcatagcct acgtcttcgt
    10261 acttccgctg gcattgcttt tcgcgctgtt ccccaagctg attctgggaa tttataccga
    10321 catacccgac ctgcaggacg ctgccgtgca ttcgctttgg gtgatgtgct ccacctatct
    10381 gttcctggtt cctgccaatg tctatttcca ggcagtttcc ggaaccggca atacgcgtac
    10441 tgcattgggc atggagctgg caacgctggt catctacaca gcctatatca cctacattat
    10501 tctgattctg caactcgacg tggccatctg ctggacctcg gaaatggttt attccagctt
    10561 tattctcatt ttctgctggc tatatatcaa acgtgggaat tggcaaggaa ggaaaattta
    10621 gtatctttgc attgaaataa ccgaaacaaa aaacatatat gaaacaagta aatctactac
    10681 ttatgtcagc agccatgaca ttggcctcct gcggaggaac aaaagatgcc ggacagcagc
    10741 aggacgcagc agtgctcatc cagcggtcgg acatcaagat tgaaggaaag cgtatgacac
    10801 ccgaggcact ctgggcgatg ggacgtatcg gcagtgtagc cgtatctccc gacgaaaagc
    10861 aaattgccta cacggtatcc tattacagcg tgccccagaa caagagtaac agcgaagtct
    10921 tcgtcatgaa tgccgacggt agtggcaata cccagataac gcatgacgcc tggcaagaag
    10981 gacagcccac atggttcaag gacggcaaga agcttgcctt cctctgcaac gaaagcggca
    11041 gcagccaggt atgggaaatg aatcccgacg gcagcggacg caagcagctg acccaatacg
    11101 agggagacat cgaagggttc tctttctcgc ccgacggcaa gaaactcctt ttcattgccc
    11161 aggtaaagac cgtgaagagt acggcagaca aacatccgga ccttcctaaa gccaccggca
    11221 tcatcgttac cgacctgatg tacaagcatt gggacgaatg ggtgactact gctccccatc
    11281 cgtttgttgc tgatttcgac ggcaatgcca tcagcaatgt cactgatatt cttgagggag
    11341 agccatacga aagcccgatg aagccctggg gcggtatcga gcagctggca tggagcccgt
    11401 cttctgataa ggtggcctat acatgccgta agaaaaccgg actggcgtat gccatttcca
    11461 ccaactccga catttatatc tacgaccttg cctccaagga aaccaaaaac atcacggaag
    11521 aaaacaaggg atatgatacg aatccccaat actctcccga cggcaaatac atcgcctggc
    11581 agagcatgga gcgtgacggc tacgaagccg acttgaaccg cttgtttatc atgaacctcg
    11641 agaccggcga gaaacgtttt gtaagcaaag ctttcgaatc gaacgtggac gccttcttgt
    11701 ggaacaaaga ttcccggagc atctacttca tcggtgtatg gcatggcgag acacagattt
    11761 acaacatcga ccttgccgga aacgacaagc ttacccagct caccgacggc atgtacgact
    11821 atgcttcgct tgccctttgc ggagacaaga ttatcgccaa acgccactcc atgagcatgg
    11881 gcgacgaaat ctatgccgta aacagtgcac gcaacggcga cgcttttgca gaagcagtgc
    11941 aactgaccac agaaaacaag cagatttacg accagctgga gatgggtaag gtggaagccc
    12001 gctggatgaa gaccaccgac ggcaagcaga tgctgacctg ggtgatttat cctccgcagt
    12061 tcgaccctaa caagaagtac cccaccctcc tcttctgtga aggcggtcct cagagtcccg
    12121 tcagccagtt ctggagctac cgttggaatt tccagattat ggcagcaaac gactatatca
    12181 tcgtagctcc caaccgccgt ggtcttcctg gcttcggtgt agaatggaac gaagccatca
    12241 gcggtgatta cggcggccag tgcatgaaag actacttcac tgccattgac gaaatggcca
    12301 aggaaccttt cgtcgacaaa gaccgcctgg gttgcgtagg tgccagcttc ggaggcttct
    12361 ccgtatattg gcttgccgga caccatgaca aacgcttcaa ggcattcatc gcacacgacg
    12421 gtatcttcaa catggaaatg caatatctgg aaacggaaga gaaatggttt gccaactggg
    12481 atatgggcgg cgcttattgg gaaaagaaca acgctacggc acaacgcact ttcgccaact
    12541 ccccgcacct cttcgtcgac aaatgggaca cccctatcct ctgcatccac ggagagaagg
    12601 acttccgcat ccttgccaac caggcaatgg ccgccttcga tgcagccgtg atgcgtggcg
    12661 ttcctgccga actgcttatc tatccggacg aaaaccactg ggtactgaaa cctcagaatg
    12721 gcgtgctgtg gcaacgtacc ttctttgaat ggctggacaa atggttgaag ccggctaagt
    12781 aaagcccctc aaaaacgata aaaacaaata gtcccggatt ctttgtcaag aatccgggac
    12841 tatttgtttt tattgtacac cgcccgattc attttttatg actataattt gggcagttca
    12901 aataaagtca atacatttgc tttatgcaca ctccgaagaa gtgtaaacaa tatgtcctaa
    12961 tataacccga taaaagatga atgaaaattg gcctgagatt gtggaaacac tgataccgta
    13021 ttttgaaaca aattcggtag aaggtgacta ccagcgggaa atagagaact gcctgaaatt
    13081 tcttggatgg aagaagacca atggaacaat ggtatcccaa tatacattac cgataggcaa
    13141 tagcaactcc atacgcccgg acattgtact ttggcgaaag aacgagcatg acacacaatc
    13201 ccccgtactc cctattgaaa taaagcgtcc gtctaatata cgaaatgaaa gacaagaaaa
    13261 tcaactgatg tcgtatatgc gccag
//
