LOCUS       c00100_gnlPro..         5188 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|JJLNGNPP_100.
ACCESSION   c00100_gnlPro..
VERSION     c00100_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-05 13:24:28
            Original ID  :: gnl|Prokka|JJLNGNPP_100
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 5188
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..5188
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[2:5187]"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      3..5187
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
     cand_cluster    1..5188
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /kind="single"
                     /product="TPP_AA_metabolism"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..5188
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="TPP_AA_metabolism"
                     /region_number="1"
                     /rules="(TPP_enzyme_C and not (PFL-like or PFL_6_pcresol or
                     PFL_9_tma or Gly_radical or Gly_430_pcre or Gly_8-9_TMA or
                     PFL_acetate1 or PFL_acetate2 or Gly_radical_scatole or
                     PFL_proline or PFL_toluene) and minimum(2, [ALS_ss_C,
                     AlaDh_PNT_C, Arginase, BKACE, BcrAD_BadFG, Beta_elim_lyase,
                     CPSase_L_D2, Cys_Met_Meta_PP, ELFV_dehydrog, GRDB,
                     Glu_syn_central, Glu_synthase, Gly_reductase, HAAA1, HG2B1,
                     HG2B2, HGD-D, HleuD1, HleuD2, HleuS1, HleuS2,
                     Homoserine_dh, ILVD_EDD, IlvC, Lactoyl-CoA1, Lactoyl-CoA2,
                     Lyase_aromatic, MAAL_C, OKR_DC_1_5_lysine,
                     OKR_DC_1_5_ornithine, OKR_DC_1_7_arginine, OKR_DC_1_C,
                     OTCace, PALP, Proline_reductase, Sacchrp_dh_C, TPL,
                     Thr_dehydrat_C, TnaA, Urocanase]) and not (POR or POR_N or
                     PFOR_II))"
                     /tool="gutsmash"
     CDS             3..968
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ILVD_EDD"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg100_1"
                     /sec_met_domain="ILVD_EDD (E-value: 2.9e-112, bitscore:
                     364.2, seeds: 918, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LHLLAVAHEAGADFKMDDIDMLSRKTPCLCKVAPNTQKYHVQDVN
                     RAGGIIAIMDELAKGGLVDTNVRRVDGMTLAEAIDRYSITSSNVCKEAIKKYSSAAAGK
                     FNLVLGSQNASYKELDTDRATGCIRDLEHAYSKDGGLAVLKGNIAQDGCVVKTAGVDES
                     IWKFTGPAKVFDSQDAACDGILGGKVVSGDVVVITHEGPKGGPGMQEMLYPTSYIKSRH
                     LGKECALITDGRFSGGTSGLSIGHVSPEAAAGGNIGKIKDGDIIEIDIPNRSINVKLTD
                     EELAARLMTPVTRNREVSKALKAYASMVSSADKGAVRLID"
     CDS             1060..2811
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg100_2"
                     /sec_met_domain="TPP_enzyme_C (E-value: 4.2e-48, bitscore:
                     151.4, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MADNNKKSTFPPPSQGEGRGEALITGAEALMRSLEHQGVKTIFGY
                     PGGSIMPVFDALYDHRKELNHILVRHEQGATHAVQGFARVSGEVGVCLVTSGPGATNTI
                     TGIADAMIDSTPIVVIAGQVGTNFLGTDAFQEVDLVGITQPITKWSYQIRRAEDVAWAV
                     ARAFYVAKSGRPGPVVLDFAKNAQVEKTEYAPTKVDYVRSYLPVPEMEPEAIRKAAELI
                     NGAERPLVLVGQGVELGEAQQELRAFIEKAGMPAGCTLLGLSALPTNHPLNKGMLGMHG
                     NLGPNINTNKCDVLIAVGMRFDDRVTGKLETYAKQAKIIHFDIDPAEIDKNVKTDVAVL
                     GDCKETLAAVTQLLEPANHQEWIDSFRQYEEVEEEKVIRPELHPAGKALSMGEVVRAVS
                     EATHNEAILVTDVGQNQMMSARYFKYSKERSIVTSGGLGTMGFGLPAAIGATFGRPDRT
                     VCVFMGDGGLQMNLQELGTIMEQKAPVKMILLNNNFLGNVRQWQAMFFNRRYSFTPMMN
                     PDYMKIASAYDIPARRVMTREELAKAIDEMIATDGPFLLEACVEEEGNVMPMTPPGGSV
                     NQMLLEC"
     CDS             2844..3404
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ALS_ss_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg100_3"
                     /sec_met_domain="ALS_ss_C (E-value: 3e-20, bitscore: 60.8,
                     seeds: 685, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDKKLYTIIVHSENFAGLLNQVTAVFTRRQINIESLNVSASSIKG
                     VHKYTITAWTDKDTIEKVTKQITKKIDVLQAHYFTDDEIYQHEIALYKITTPTLEEKPE
                     VSKVIRKYNARIVEVNAVFAIVEKNGMSEEITNLYEELRQLDCVLQFVRSGRVAITTSC
                     FERVNEYLADREAKYRQSKHQES"
     CDS             3401..4153
                     /locus_tag="ctg100_4"
                     /transl_table=11
                     /translation="MMSENNKIGTYKFVAEPFHVDFTGRLTMGVLGNHLLNCAGFHASD
                     RGFGIATLNEDNYTWVLSRLAVELDEMPYQYEDFSIQTWVENVYRLFTDRNFAIIDKEG
                     KKIGYARSVWAMISMNTRKPADLLALHSGSIVDYVCDEPCPIEKPSRIKVASKEPVAAL
                     VAKYSDIDINGHVNSIRYIEHILDLFPIEMYKEKRIRRFEMAYIAESYYGDELTLFMDD
                     AGEGVYDVEVKKNGSEVVCRSKVIFTEK"
     CDS             4204..5187
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: IlvC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) IlvN"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg100_5"
                     /sec_met_domain="IlvN (E-value: 1.7e-47, bitscore: 149.5,
                     seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="IlvC (E-value: 4.6e-37, bitscore: 116.0,
                     seeds: 295, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAQLNFGGVIENVMTREEFPLEKAREILKDETIAVIGYGVQGPGQ
                     ACNLRDNGFNVIVGQRPGKTYEKAVADGWVPGETLFGIEEACQKGTIVMCLLSDAAVMS
                     VWPTIKPYLTPGKALYFSHGFAITWNDRTGVVPPKDIDVIMVAPKGSGTSLRTMFLEGR
                     GLNSSYAVYQDATGKAFDKTIALGIGIGSGYLFETTFIREATSDLTGERGSLMGAIQGL
                     LLAQYEVLRENGHTPSEAFNETVEELTQSLMPLFAKNGMDWMYANCSTTAQRGALDWMT
                     PFHDAIKPVVQKLYASVKSGNEAQISIDSNSKPDYREKLNAELKALR"
ORIGIN
        1 tacttcattt gttggctgtg gctcacgaag ccggagcgga ttttaagatg gacgatattg
       61 acatgctctc ccgcaagacc ccctgcttat gcaaggtggc tcccaatacc caaaagtatc
      121 atgtacaaga cgttaaccgt gccggtggca tcattgccat catggatgag cttgccaagg
      181 gcggattggt cgatacgaat gtccgccgtg tggatggaat gacgttggca gaggcaatcg
      241 accggtatag tattaccagc tctaatgtat gtaaagaggc aatcaagaaa tactccagtg
      301 cggcagccgg aaagttcaat ctggtactcg gctcacaaaa tgcgtcttat aaggaactcg
      361 atacggaccg tgcgaccggt tgtatccgtg atttggaaca tgcatacagc aaggatggcg
      421 gtctggcggt tttgaaggga aatatagctc aggacggttg cgttgtcaag actgccggtg
      481 tagacgagag tatctggaaa tttacggggc cagcgaaagt cttcgactca caagatgcgg
      541 cttgtgacgg tattctgggt ggaaaggtgg tcagtggaga cgtcgtcgtc atcactcacg
      601 aagggccgaa aggtggaccg ggtatgcaag agatgcttta tcctacttct tatatcaaat
      661 cccgccatct gggtaaggag tgtgcattga ttaccgacgg gcgtttcagt ggtggtactt
      721 ccggactaag tatcggacat gtttctcccg aagcggctgc cggtggtaat atcggcaaga
      781 ttaaggatgg ggacattatc gaaattgata taccgaaccg ttctatcaat gtgaagttga
      841 cggatgaaga gcttgcagca cgccttatga ctccggtaac ccgcaaccgt gaagtctcca
      901 aagcattgaa agcatatgcc agtatggtga gttccgctga caaaggggct gtgaggctga
      961 ttgattaaaa gccccccttt ccgaaagcga ggggaggaga gaatgaaaca aatttttcaa
     1021 gctactattg agcttttaaa tataatgaat agataaagta tggctgataa taataaaaag
     1081 agtacctttc cccccccctc ccaaggagag ggtcggggtg aggctctaat aacaggcgca
     1141 gaagcattga tgcgctctct ggagcatcag ggagtaaaga ctattttcgg ttatccggga
     1201 gggagcatca tgccggtatt cgatgcctta tacgaccacc ggaaggaatt gaaccacatc
     1261 ttggttcgcc atgaacaagg agcaacccat gcggtacaag gctttgcacg tgtatcaggc
     1321 gaggttggcg tttgtctggt taccagtgga ccgggtgcta ccaatactat cacgggcatt
     1381 gcagatgcca tgattgacag tacgcctatc gttgtcattg ccggccaggt agggacgaac
     1441 ttcttgggta cggatgcatt tcaggaagtg gacttggtag gcattactca gcctatcacg
     1501 aaatggagtt accagattcg tcgtgcagaa gatgtggcct gggcagtggc acgtgctttc
     1561 tatgtggcaa agagcggacg tccgggaccg gtcgtgctgg attttgctaa aaacgcccaa
     1621 gtggagaaaa cagaatatgc gcctactaag gtggactatg tccgtagcta tcttcccgtt
     1681 cccgaaatgg agccggaggc catacggaag gctgctgaat taataaatgg tgcggaacgg
     1741 cctttggtgc tggtaggaca aggcgtggag ctgggagaag cccagcaaga gcttcgtgct
     1801 ttcattgaga aagccggaat gcctgccgga tgcactttat tgggactttc cgcattacct
     1861 acgaaccatc cgttgaacaa aggaatgctt ggtatgcacg gtaacctggg gcccaatatc
     1921 aataccaata aatgtgatgt ccttatcgcc gtaggcatgc gctttgatga ccgtgtgacg
     1981 ggtaaattgg aaacatatgc caagcaggcg aagattatcc actttgatat tgaccctgcc
     2041 gaaatagata agaatgtaaa gaccgatgtt gctgtcctgg gagattgcaa agagacactg
     2101 gctgccgtta cccaattgct ggaacccgcc aaccatcagg aatggattga cagtttccgg
     2161 caatacgagg aagtggaaga ggaaaaggta atccgtccgg aattacatcc ggcaggaaaa
     2221 gcgctaagca tgggtgaggt ggtgcgtgct gtgagtgagg ctacccataa cgaggcgata
     2281 ttggtgactg atgtcggcca gaatcagatg atgtccgccc gttatttcaa atacagcaag
     2341 gaacgtagca ttgttacttc cggtggcctg ggtactatgg gcttcggcct tccggcagct
     2401 atcggtgcca cttttggacg tccggaccgc acggtatgcg tattcatggg agacggcggc
     2461 ttgcagatga acctgcagga actgggtacc atcatggaac aaaaggctcc ggtgaagatg
     2521 attctgttga acaataactt cctgggcaat gttcgtcaat ggcaggcgat gttcttcaat
     2581 cgtcgttatt cgtttactcc gatgatgaat ccggattata tgaagattgc ttcggcatat
     2641 gatattcctg cacgcagggt aatgacccgc gaggagctgg caaaagcgat tgacgagatg
     2701 atagcgactg acggaccgtt cctgctcgaa gcttgtgtgg aggaagaagg aaatgtaatg
     2761 ccgatgacac ctccgggcgg ttcggtcaat cagatgttgt tggaatgctg aagtcatgcg
     2821 aaattaaaga atttactcta tctatggata aaaaactata tacaatcatt gttcattcgg
     2881 aaaactttgc cggtttgctg aatcaggtga cggctgtgtt tacccgccgg cagataaaca
     2941 tcgagagttt gaatgtatcg gcctcctcca tcaagggggt acataaatat accattaccg
     3001 cttggacgga caaggatacc attgaaaagg tgaccaagca gattaccaag aaaatagatg
     3061 tgctgcaagc ccattatttc acggatgatg aaatctatca gcacgagatt gccctttata
     3121 aaataacgac ccctacgctg gaagaaaaac cggaggtgtc caaagtaatc cgtaagtaca
     3181 atgcccgtat tgtggaggtg aatgctgtat ttgccattgt tgagaagaat ggcatgagtg
     3241 aggaaataac caatctttat gaggagttgc gccagttgga ttgcgtactt cagttcgtcc
     3301 gttcgggtcg cgtagccatt acgaccagct gctttgagcg tgtcaatgaa tatctggcgg
     3361 accgtgaagc aaaatatcgt caaagtaaac accaggaatc atgatgagcg agaacaataa
     3421 gataggtacc tacaagtttg ttgccgaacc gtttcatgtc gactttaccg gacggctgac
     3481 aatgggagta ttgggcaacc atttgttgaa ttgtgcgggt ttccatgcca gcgaccgcgg
     3541 ttttggcatc gcgactctaa acgaggacaa ttatacttgg gtattgtccc gtctggctgt
     3601 cgaactggat gaaatgcctt atcagtacga agatttctcc attcagactt gggtggagaa
     3661 tgtctatcgc ctttttacag accgtaattt cgctatcatc gataaggagg gtaagaagat
     3721 tgggtatgca cgttccgttt gggcgatgat tagcatgaat acccgtaagc cggcagattt
     3781 gctggctctt catagtggca gcattgtaga ttatgtttgc gatgagcctt gcccgataga
     3841 aaaaccttcg cggataaagg tggcctcaaa ggaaccggtt gctgctttgg tagccaaata
     3901 cagtgatatt gacattaacg ggcatgtgaa cagcatccgt tacatcgagc atatccttga
     3961 tttgttcccg atagagatgt ataaggagaa gcgcatccgt cgttttgaaa tggcatatat
     4021 agccgaaagc tattatgggg atgagttgac tttgttcatg gatgatgccg gtgagggcgt
     4081 ttacgatgtg gaggtgaaaa agaatggcag cgaagtggtc tgtcgctcta aagtgatatt
     4141 tacagagaaa taaataaatt tatcaacgtt ggcgtaagcc acaaataaaa attaaaacaa
     4201 aaaatggcac aattgaattt tggcggtgtt attgagaatg taatgacccg cgaagaattt
     4261 cctttggaaa aagcacgtga gattttgaaa gatgaaacaa ttgcagtaat cggttatggc
     4321 gtacaaggcc cgggccaggc ttgcaacttg cgtgataacg gtttcaatgt gattgtagga
     4381 caacgtccgg gtaagacata cgaaaaggct gtggctgacg gatgggtacc gggtgagact
     4441 ttgttcggca tcgaagaggc ttgtcagaaa ggtactatcg tcatgtgtct gttgtctgac
     4501 gcagctgtaa tgtctgtatg gccgactatc aaaccttatt tgactcccgg aaaggctctt
     4561 tacttctctc atggttttgc tattacctgg aacgaccgta ccggcgtggt tcctcctaaa
     4621 gatattgatg ttattatggt tgctcccaaa ggttccggta cttcacttcg taccatgttc
     4681 ctcgaagggc gtggcttgaa ctcatcatat gccgtctatc aggatgctac gggtaaggct
     4741 tttgacaaga cgattgcact gggtatcggt atcggttcgg gatatttgtt cgagacaact
     4801 ttcatccgcg aagccacttc cgacttgacc ggtgaacgcg gttcattgat gggtgctatc
     4861 cagggattgc tgttggctca gtatgaagta ttgcgcgaaa acggtcacac tccttctgaa
     4921 gcattcaatg aaactgtgga agagttgact caatctttga tgccattgtt tgccaagaat
     4981 ggtatggact ggatgtatgc caactgttct actacggcac agcgtggtgc gctggattgg
     5041 atgaccccgt tccatgatgc catcaagccg gttgtacaga aattgtatgc aagcgtgaag
     5101 tcgggtaacg aagctcagat ttctatcgac agcaactcca aacccgatta tcgtgagaag
     5161 ctgaatgcag aattgaaagc cttgcgtg
//
