LOCUS       gnlProkkaCBNGDKLJ_36   12384 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|CBNGDKLJ_36.
ACCESSION   gnlProkkaCBNGDKLJ_36
VERSION     gnlProkkaCBNGDKLJ_36
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-12-02 06:13:28
            Original ID  :: gnl|Prokka|CBNGDKLJ_36
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 12384
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..12384
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[2117:2384]"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      2118..2384
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
     cand_cluster    1..12384
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /kind="single"
                     /product="RRE-containing"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..12384
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="RRE-containing"
                     /region_number="1"
                     /rules="minimum(1, [Bottromycin_Methyltransferase_RRE,
                     Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /tool="antismash"
     CDS             complement(3..923)
                     /gene_functions="transport (smcogs) SMCOG1288:ABC
                     transporter related protein (Score: 81.3; E-value: 1e-24)"
                     /gene_kind="transport"
                     /locus_tag="ctg36_1"
                     /transl_table=11
                     /translation="MKKQQKDKKVKKDRREKLRYIREVSAEQRGRILLSCLTGILGVAF
                     ALAFIYATKRVIDTATGITDDNLTHVAVLTVVLLTAQLLCGAADTWISTRMQIETGNAL
                     RHRLFSRLLQSRWNELERFHTGDVVNRVEQDTAAIVTLLTSSVPAFIVTSIQLLAAFLF
                     FYFLDPSLPWLIVAILPVFLLGSRFYMRRMKRYTHDIRNSDGRIQSVIQESLQHRIVIK
                     TLEQGERHLDKLDDLQDMLHSQVMGRTRFSLSAHMLVALAFSGGYLTAFLWGAVHLSAG
                     CITFGTMTAFLQLVGKVQRPVLDLSR"
     CDS             complement(946..2109)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NTP_transf_5"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg36_2"
                     /sec_met_domain="NTP_transf_5 (E-value: 1.3e-46, bitscore:
                     149.3, seeds: 77, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQHAFFSLVRSGLWGTPADRQLFRSVSPDDWETVYRMANSQALLA
                     LTFDGISSLPAELRPPRALYLKWAARTAQIEQANKRLNQLLPELNTLYREAGLHPVLLK
                     GQGIGTNYRTPLHRQCGDIDIYLGKQGQPIANRLLLQQGAIVEGEASDKHASYSLKGVH
                     IENHRIILRLNSPLANRHFQQIIRKWYPQETDYALFSETGKEDSKAVSIAIPPATFNAL
                     YIFLHAFVHFLNSGIGLRQLCDWTCLLANRHKEIDATTLLRQLQDLGLLHAAQAFGYIA
                     VTRLGLPANRLPFPLEGTKQIGEQLLEDILSTGNFGQHDNRIKPRPKGYWAGKWYTFCR
                     ATRRCNELRQFAPYEALWYPVTLIGGTIAIQINRLKGVKDKKARTKK"
     CDS             complement(2118..2384)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: Stand_Alone_Lasso_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg36_3"
                     /sec_met_domain="Stand_Alone_Lasso_RRE (E-value: 1.3e-13,
                     bitscore: 41.0, seeds: 25, tool: rule-based-clusters)"
                     /sec_met_domain="PF05402 (E-value: 6.3e-16, bitscore: 48.7,
                     seeds: 461, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKIKQGFILHRIGDDYIIMQDGSSNVDFSKVISLNQTSAMLWQEI
                     ENKEFDTDSVTEALTSRYDVDNESARRDAQKFIDSLDREGIIE"
     CDS             complement(2397..2837)
                     /locus_tag="ctg36_4"
                     /transl_table=11
                     /translation="MKKSIPNEILLPEVARLIKEGHTVTITVRGNSMNPFLVDRRDRVT
                     LGDFTTEQLQPGVAVLARDLTERIVFHRIIRRNGNILILQGDGNLAQTEETDIGRVMGV
                     MTEAMRKDKRYTADGKVWKLYSYWWMKLNPARRWLLALFRRI"
     CDS             complement(2864..3790)
                     /locus_tag="ctg36_5"
                     /transl_table=11
                     /translation="MRIQILDYQVGPHTFRMVKPSDFNIFKALPSLIPFITTIDTTQKV
                     IFETEIDDDETATKRTIAKTPDDICFNWEDADCIIRPLPHSSHLVSITPRKSGKNYWME
                     CNDNFRQCFIHLPACRTETPAPENETNFVLNNFLMMLYAFNAARHHTLLMHASVVATET
                     GKGYLFLGKSGTGKSTHTGLWLQQFSDCHLLNDDNPIVHVDSLGKQATVFGSPWSGKTP
                     CYRKESMTVGAFVRLEQAPQNEIEQERAAHAFATLLPSCSCLKQNKEIYNAIVTTVTEL
                     ATLAPVYHLKCLPDREATELCRKAVEG"
     CDS             complement(4037..7615)
                     /locus_tag="ctg36_6"
                     /transl_table=11
                     /translation="MMKLRNLMQVACMATAALTAFSCSQEEFENSGRKGNITVNATFEG
                     AGTDTRTTVNDEYKILWQDTDALGLFCSNAESNYSNTKLEYASGAGQTSATFNGSKPSG
                     ETAVFSIYPYQQNMSVSGNTLTMTLPATLTNYNGSSNGPMYAKVTNPDNLSALSFKHMA
                     AMIKLTVNKIPAEATTFKIIASNNIAGTCTVDLTAADPILAVTSDESKEITASFTASAD
                     IKSRNFYIPLPTGTYSSITAQLTNGSDKVYFTKTLNDKILGRRDILVVPPLDCVVVEAT
                     TPSALSTALADSKNLPQEAPTAATVTDIAVSGSFNTTSGSNDGIAIPVLQNSDINLAFN
                     TAPTTSTAAPLTLTDKTNTSIGAPAATATNSVSLAVPETNAEQEAPSVAITMPSTTVTL
                     AAVGNKATYNEVTATTAQQTLIINAGVTVKKLTVKGGNLKIYGKVEQLVHDAGDTTIYI
                     IKGTEASLPATIDSKFVVQSDVAVLKAAFANGEDFKLSADADITGQSVSVPAGKSVVLD
                     LNGYTLTADNSATGKIIVLGKMTLKDSSTEKKGKIVASQDYTAASYNGSLIEIAGEDAS
                     MTMESGNISAVRKTPNSNGQYGVGVTDGGDFTMTGGKIEAGWFAVAGNGNYKTQNSIIN
                     ITDGELISTADYAVYLPQSGTTTISGGKVYGAAGGVCIQRGTLNVEGTALITSKGTGST
                     GNWGDGTGGLDCAAINVSGAYGIATVNIKGGTLIAEAKSLITEGTTYTPVINVTGGTFS
                     DPSALKYMKTNANVNIKLTADKTCPGFKTTSGQTLTMDLGGKILTLADPTVGSTGTETN
                     SCQLLEGSNVTFKNGTLKSDNNKIMIQNYCNLTLDNMTVEDTNAQYVVSNNCGNISINN
                     TTINAGSNANQFAFDVCGYAKYTAGVTVTVSGTSVINGKVEISKSAGNTEPMKLNITGG
                     TFNGDLKVDASVGTENAKSIISVSGGTFSDPSVLKYMATNATVDIKLLSNINIAKTELA
                     TGYILNAANATANLNLNGHDIINSSETADATPFTQIFTVQNGTLNISGNGNVKCDASAT
                     AKDDGYRMVIEARGHGTVNIHGGSYYNTQKLNTQIDLIYARENGKINIYGGTFESGKYG
                     TPNNDTDGRYWVLNLKNTDKNTASIQVSGGTFINFNPANPNMDDNESYLVTGYEVTRDG
                     SVYTAAHKVNDGRKEYIVGPTSQENR"
     CDS             complement(7629..7844)
                     /locus_tag="ctg36_7"
                     /transl_table=11
                     /translation="MKQNKPDGREAYITPSIEVIKMENEGVIATSGEPYHPITRSYSGS
                     TSTHSYNSASSSDLEDLINDILTVEN"
     CDS             7894..8070
                     /locus_tag="ctg36_8"
                     /transl_table=11
                     /translation="MFVYPLFRPSHCPFPGYTTVTHVVCVYTIPLMGENHINIDVSILV
                     VIFREIFKVAKFE"
     CDS             complement(8210..8569)
                     /locus_tag="ctg36_9"
                     /transl_table=11
                     /translation="MDICKNMESLIMKNCYGIDFRSWRKELRTREKTKQTPCKLPDRVS
                     RSLQGVLFKVYQISVLILLKKILFSFFSVCLPLFIRHIAAMLLRKTSSKTMQTVTKYLK
                     ELSGVRSDNSPNSYK"
     CDS             9402..9734
                     /locus_tag="ctg36_10"
                     /transl_table=11
                     /translation="MKQLIACCGLDCENCAARIATVNNDDELREKTAKEWSVLNNTPEI
                     TAETIHCMGCRADGVKFAYCSDYCAIRKCVYEKGFNTCGDCKELETCQVVGAVLQHAPG
                     AKENLY"
     CDS             9968..10744
                     /NRPS_PKS="Domain: oMT (51-145). E-value: 6.2e-11. Score:
                     32.8. Matches aSDomain: nrpspksdomains_ctg36_11_oMT.1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089:methyltransferase (Score: 78.7; E-value:
                     7.7e-24)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg36_11"
                     /transl_table=11
                     /translation="MSNENKTIHDFELSLICDFFSNMERQGPGSPEATLKALSFVDGLT
                     DKSLIADIGCGTGGQTIVVAGHVPGRITGIDLFPGFIDIFNRNARQLGLQDRVKGIVGS
                     MDALPFGEEELDMIWCEGAIYNIGFERGLKEWRKYLKPGGYIAVSESSWFTDERPAEIN
                     DFWMDAYSEMDTLPNQVAKLYKAGYLPVATFILPENCWTEHYFASKVAAQEIFRKKYAG
                     NKIAEEFSSLQMIEDELYGKYKEFYGYVFFIAKKVG"
     aSDomain        10121..10402
                     /aSDomain="MT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg36_11_oMT.1"
                     /domain_subtypes="oMT"
                     /evalue="6.20E-11"
                     /label="ctg36_11_oMT.1"
                     /locus_tag="ctg36_11"
                     /protein_end="145"
                     /protein_start="51"
                     /score="32.8"
                     /tool="antismash"
                     /translation="DIGCGTGGQTIVVAGHVPGRITGIDLFPGFIDIFNRNARQLGLQD
                     RVKGIVGSMDALPFGEEELDMIWCEGAIYNIGFERGLKEWRKYLKPGGY"
     CDS             complement(10819..11667)
                     /locus_tag="ctg36_12"
                     /transl_table=11
                     /translation="MNISEFNINAEFIACNHITTNELNPLVEKPYHTKASIFALCTKGV
                     LKTIINHTQFRVEANTLLVIPPETFVQLLHTSDDAEIYVVIFSQQLIQSSGAGKVMMDK
                     FHIIGKHYIFPLSKTDFQLYAEFMTYLSHLYQRTESPSSLVSLQTLLTYLLQGISELCP
                     ERPRIKETPGSRHFNQYRIFIRLVHTDYVREHQVSYYALKMNMRPAALCRLVKKESGHT
                     AMEIINNTIIMDAKAQLCTANTPIKDIAVSLGFNNAAFFNKFFKRHTGIPPQKFRTSSK
                     Q"
ORIGIN
        1 aggcgtgaga ggtcgagcac gggacgctgg acttttccta ccaattgcaa aaaggcggtc
       61 atcgttccga aggtgataca gcctgcgctg aggtgaacgg ctccccaaag aaaagccgtg
      121 aggtatccgc cggaaaaggc aagggccact aacatgtggg cggaaagcga gaaacgggta
      181 cgtcccatga cttggctgtg gagcatgtct tgcaagtcat cgagtttgtc cagatgccgt
      241 tcgccttgtt ccaatgtttt aatcactatg cgatgttgca ggctctcttg tatgacggac
      301 tggatgcgac cgtcactgtt ccgaatatca tgtgtatagc gtttcattcg tcgcatatag
      361 aaacggctgc ctaatagaaa gacgggcagg atggcaacaa tcagccatgg cagtgaaggg
      421 tctaaaaagt agaagaatag aaaggctgcc agcagttgta tactcgtgac gatgaatgcc
      481 gggacagaag aggtgagcaa tgtgacgatg gcggcggtgt cttgttctac ccggttcact
      541 acgtctccgg tatggaaacg ctccaattcg ttccagcggc tttgcagtaa gcgcgagaag
      601 aggcggtggc gaagggcgtt gcccgtctct atctgcatac gggtacttat ccaagtgtca
      661 gcagctccgc acagtaattg ggcagtcagc aggacaacgg tgagaacggc gacatgcgtc
      721 aggttgtcgt ctgttattcc ggtagcggtg tctatcaccc gtttggttgc atagataaag
      781 gctagggcaa aggccacgcc cagaatgccg gtgaggcaac ttagcaggat acgtccgcgt
      841 tgttcggcag atacctctcg aatataccta agtttttcac gtctgtcctt tttcactttt
      901 ttgtccttct gttgcttttt cattcctttt attttccggg ttcttttatt tctttgtcct
      961 tgctttcttg tcttttactc cttttaatcg gtttatttgt atagctatcg ttccccctat
     1021 cagagtcacg ggataccaga gtgcttcgta cggtgcaaat tgacgcagtt cgttgcagcg
     1081 tcgggtggcg cggcagaagg tgtaccactt tcctgcccaa tatcctttgg ggcgtggctt
     1141 gatgcggtta tcatgttgcc cgaagttacc ggtagacagg atgtcttcca ataattgttc
     1201 tcctatctgc ttggtgcctt ccaaggggaa aggaagccgg ttggcgggca atcccagtcg
     1261 ggtgacggca atgtagccga atgcttgtgc ggcatgcaat agtccgaggt cctgcaactg
     1321 gcgaagcagg gtggtggcat ctatttcttt gtggcgattg gcaagcagac aagtccagtc
     1381 gcatagctgg cgcaggccga ttccgctgtt caggaaatgt acaaaggcat gcaggaagat
     1441 ataaagtgca ttgaaggtgg ccggaggtat ggcgatactg acggccttcg agtcctcttt
     1501 cccggtttcg gagaataggg catagtctgt ttcctgcgga taccattttc tgataatctg
     1561 ctgaaagtgc cggttggcaa gcggactgtt cagccggagg atgatgcggt ggttctcgat
     1621 gtgtactcct ttcaaactgt agctggcatg cttgtcggac gcttctccct cgactatggc
     1681 gccttgttgc agcaggaggc ggttggctat gggttgtcct tgttttccta aatagatgtc
     1741 gatgtctccg cattgccggt gcaagggagt gcggtagttg gtgccgatgc cttgcccttt
     1801 cagcagtacg ggatgcagcc cggcttcccg gtaaagggta ttgagttcgg gcagaagctg
     1861 gttgaggcgt ttgttggctt gttctatctg tgcagtccgg gcagcccatt tcagatagag
     1921 ggcgcgtgga gggcgcagtt cggccggtag actgcttatg ccgtcaaaag tcagtgcaag
     1981 cagggcttgt gagtttgcca tgcggtacac ggtttcccag tcgtccggcg agaccgaccg
     2041 gaagagttgt cggtctgccg gagtgcccca caggccggag cgtaccaatg aaaagaaagc
     2101 gtgttgcata tccgtcctta ttctatgatt ccttcgcggt caagggagtc gataaacttc
     2161 tgcgcatcgc gacgggccga ttcgttatct acatcatagc ggctggtcag ggcttctgtc
     2221 acgctgtctg tatcgaactc tttgttttct atctcttgcc aaagcatggc ggaagtttgg
     2281 ttcaggctga tgactttgct gaagtccacg ttcgacgagc cgtcttgcat gatgatgtag
     2341 tcatcgccta tccggtgcag gataaatcct tgtttgattt tcatggttat tttgttttat
     2401 attcttctga acagggcgag cagccagcgg cgagcagggt ttagcttcat ccaccagtag
     2461 gagtagagct tccagacttt gccgtcggcg gtgtaccgtt tgtcttttcg catggcttcg
     2521 gtcatgacgc ccattacccg tccgatgtcg gtttcttcgg tctgggcgag gttgccgtcg
     2581 ccttgcagga tgagtatatt tccgttccga cggatgatgc ggtgaaagac gatgcgttcc
     2641 gtcaggtcgc gtgccagtac ggcgacgccc ggttgcagct gttctgtggt gaaatcgccc
     2701 agtgtcaccc ggtcacggcg gtccactaag aaaggattca tgctgttgcc ccgcacggtg
     2761 atggttactg tatgcccctc tttgatgaga cgcgccactt cgggaagcaa tatctcgttg
     2821 ggaatgcttt tcttcatcgg ctgttcagtt catcattcat aacttatcct tctaccgcct
     2881 ttctgcaaag ctccgtcgct tcacggtcgg gcaggcattt cagatgatag acgggtgcca
     2941 gcgtggcaag ttccgtcaca gtggtgacaa tggcgttata gatttccttg ttctgcttca
     3001 ggcaagagca ggaggggagg agggtggcga aagcatgtgc tgctctctct tgctctattt
     3061 cattctgcgg tgcttgttcc aagcggacga aggcacctac ggtcatggat tctttccgat
     3121 agcatggtgt ctttccgctc catggagaac cgaaaacagt ggcttgcttg ccgaggctgt
     3181 ccacatgtac tatcggattg tcatcgttca gtagatggca gtccgagaac tgttgcagcc
     3241 agagcccggt gtgcgtactt ttgcccgtgc cgcttttccc taagaagagg tagcctttgc
     3301 ctgtttcagt agcgacaacc gaggcatgca tcagcagtgt atggtggcgg gcggcattga
     3361 aggcatagag catcatcaag aagttgttca gtacgaagtt cgtttcgttt tccggagccg
     3421 gtgtttctgt cctgcaggcc ggtaggtgga tgaagcattg cctgaagtta tcgttgcact
     3481 ccatccaata gtttttcccg cttttccgtg gggtgatgga tacaaggtgt gagctgtggg
     3541 gcaaagggcg aatgatgcaa tcggcatctt cccagttgaa acatatatca tcgggagttt
     3601 tcgctatggt tcgttttgtc gctgtttcgt catcgtctat ctctgtttca aagattactt
     3661 tttgcgtcgt gtctattgtc gtgatgaacg gaatcagtga aggcaacgcc ttgaatatat
     3721 tgaagtcgga aggtttcacc atgcggaagg tgtgcggtcc tacttgataa tccaatatct
     3781 gtattctcat atgttttgat tgttagttgt tattcatgat actttgggct actcagaaaa
     3841 ataatgaatg tttgtgtgaa tgaggaagat ttgagagatt tttcaactgt cttgttgtca
     3901 ttttttagac gcggaggacg cagatttata aaagaaaatc cgctgtccgc cgcatctaaa
     3961 agatagtaat aaggcgattc cgatacctct tcgtttggtc tgcgaggata tattgcttcc
     4021 tttcttagaa tttggcttat cggttctcct gacttgttgg gccaacaata tattctttcc
     4081 tcccatcgtt gactttgtgg gctgctgtat atacactgcc gtcacgggta acctcgtaac
     4141 ctgttaccaa ataggattca ttgtcgtcca tattcggatt tgccgggttg aaattgatga
     4201 acgttccacc ggacacctgg atgctggcag tgttcttgtc tgtattcttt aagttcagta
     4261 cccagtatct gccatccgtg tcgttgttgg gtgtaccata tttgccggat tcaaatgttc
     4321 ctccatagat attgattttc ccattctctc ttgcataaat caggtctatc tgggtgttca
     4381 gtttctgggt gttatagtaa gaaccgccat gaatatttac tgtcccgtgt cctcgggctt
     4441 caattaccat gcgataacca tcgtctttcg ctgtagcaga tgcatcgcac ttcacattgc
     4501 cgttgcctga aatgtttagt gttccgttct gtacagtaaa gatttgtgtg aaaggagtgg
     4561 catcagctgt ttctgaggaa ttgatgatgt cgtggccatt caggtttaag tttgccgttg
     4621 cgtttgcagc attcaatatg tagcctgtgg caagctccgt cttggcgatg ttgatatttg
     4681 agagaagttt tatatccaca gttgcgttgg ttgccatgta cttcagtacg cttgggtcgg
     4741 agaatgtacc tccggaaaca gagatgatac ttttggcatt ttcggttccc acggatgcat
     4801 ctacctttaa gtcaccgttg aaagtaccgc ctgtgatatt cagcttcata ggttcggtat
     4861 ttcctgcact cttggaaatt tccacttttc cattgatgac gctcgtaccg cttaccgtaa
     4921 ccgtgactcc agcagtgtac tttgcatagc cgcatacgtc gaatgcaaat tgattcgcat
     4981 tgcttcctgc gttgatagtg gtattgttga tgcttatatt gccacaattg ttgcttacta
     5041 cgtattgggc atttgtgtct tctactgtca tattatctaa tgtcaggttg cagtagttct
     5101 gaatcatgat tttgttgttg tcactcttca gcgttccgtt cttgaaagta acgtttgaac
     5161 cttcgagtaa ttgacagctg ttcgtttcgg tgccggtgga acctacggtc gggtcagcaa
     5221 gtgtaaggat cttgccgcct aagtccatcg tcaaggtttg tccgcttgtg gtcttgaatc
     5281 ccgggcaggt cttgtcggcg gtcaacttta tgttcacatt tgcatttgtc ttcatgtact
     5341 tcagcgcgct tgggtcggag aatgtaccgc cggtaacgtt gatgaccggt gtataagtgg
     5401 tgccttctgt gatgagtgac tttgcttcgg caatcagtgt accgcctttg atgtttactg
     5461 tggcaatgcc atatgctcca cttacgttga tggcggcgca gtccagtcct ccggtaccgt
     5521 ctccccagtt gccggtgctg cctgtgcctt tactggtaat caaggctgtg ccttccacgt
     5581 tcagagtgcc tcgttggatg catacacctc ctgcggcacc ataaaccttg ccgccactga
     5641 tggtcgttgt gccggattgg ggcagataga ctgcatagtc agcagtagaa atgagttctc
     5701 cgtctgtgat gttgatgatg gagttctgcg tcttgtaatt gccgttgcct gccactgcaa
     5761 accatccggc ttctatcttg ccgcctgtca tggtgaagtc tccaccgtcc gtcactccga
     5821 cgccatattg gccgttactg ttcggagtct ttctgactgc actgatgttg ccgctttcca
     5881 tggtcatgga ggcatcttca ccggctattt caatcagact gccattataa gaagccgctg
     5941 tataatcctg gctggcaact atcttgcctt tcttctcggt agagctgtcc ttcagtgtca
     6001 tcttgcccaa gacgatgatt ttgcctgttg cgctgttgtc ggcagtcagt gtatatccgt
     6061 tcaagtcaag aaccacggac tttccggcgg gtacactgac gctttgccct gtgatgtcgg
     6121 catcggcgga caatttaaaa tcttcgccgt tggcgaaagc ggcctttagg actgccacgt
     6181 cggattgaac tacaaatttg ctgtcgattg ttgccggaag tgatgcttcg gttcctttta
     6241 ttatatagat tgtggtatcg ccggcatcgt gtaccaattg ttctaccttt ccatatatct
     6301 tcaagttacc gccttttacg gtcagcttct ttacggtgac gcctgcattg ataatcaatg
     6361 tctgctgggc ggtagtggca gtcacttcat tgtaagtggc tttattgcct actgctgcca
     6421 atgtaacggt ggtgcttggc atggtgatgg ctacagaagg agcttcttgc tctgcattgg
     6481 tttccggcac agccaaggat acactgttgg tggcagtggc ggcgggagca cctatgctgg
     6541 tattggtctt gtcggtcagc gtcaacggag cggcagtact ggtcgttggg gctgtattga
     6601 acgccaggtt gatgtccgag ttctgtaaaa ccgggatggc gatgccgtcg ttgctgccgg
     6661 aagtggtatt gaagctgccg ctgactgcaa tgtcggttac ggttgctgct gtcggtgctt
     6721 cttgtgggag attttttgaa tcagctaaag ctgtactaag cgcactgggg gttgtagcct
     6781 ctaccacaac gcaatccaaa ggaggtacta ccaatatgtc tcttctgcct aggattttgt
     6841 cattaagcgt cttggtaaaa tataccttgt cgcttccatt cgtcagttgg gcagtgatgg
     6901 aactataagt acctgtgggc aaaggaatgt agaagttgcg agactttata tcagctgagg
     6961 ctgtgaagga ggcggtgatt tccttgcttt catcgctcgt tactgccagt atcgggtctg
     7021 ctgcggttaa gtctaccgta caagtacctg caatgttatt ggaggcaata atcttgaaag
     7081 tagtggcctc tgccggaatc ttgttgacgg tcagttttat catggctgcc atgtgcttga
     7141 aggacagagc gctcagattg tcgggatttg tcaccttggc atacatcggg ccattgctgc
     7201 tgccgttata atttgtaagc gtggcaggta gagtcatggt caatgtattg ccgcttacgc
     7261 tcatgttttg ttggtaagga tagatggaga atacagccgt ttctccgctt ggcttgctgc
     7321 cgttgaaagt ggcggaagtt tgaccagcac cgcttgcata ttctaatttt gtattgctat
     7381 aattactttc tgcattacta cagaacaacc ctagggcatc ggtatcttgc catagaatct
     7441 tgtattcatc gtttacggta gtacgggtgt cggtacctgc gccttcaaac gttgcgttaa
     7501 cggtgatgtt tcctttccgc ccgctgtttt caaattcctc ttggctgcaa ctgaatgcgg
     7561 tcaaggcagc agttgccatg caggcaactt gcataaggtt tcttaatttc atcataatga
     7621 agtccccctt agttttctac ggttaagatg tcattgatta ggtcttccaa gtcgctgctg
     7681 gatgccgaat tgtagctatg ggtagaggtg ctgcccgaat aggagcgcgt aatgggatgg
     7741 taaggttcgc cgcttgttgc aatgactcct tcattctcca ttttgataac ttcgatagac
     7801 ggagtgatgt atgcttctct accgtctggt ttgttctgtt tcatatacac aaattattta
     7861 aaggttaaac aataaaaaaa aacgtgagta actatgtttg tatatccttt attcaggcct
     7921 tcgcattgcc ctttccctgg atatacaaca gtcactcacg tcgtttgtgt atataccatc
     7981 cccctgatgg gagaaaacca tataaacata gacgtgagca tccttgttgt tatcttcagg
     8041 gaaattttca aagttgcgaa gtttgaataa agaagataat ttcaataatg ctcttactaa
     8101 tatgtaaata aacccactac gctatagcga atttgtgaca aagataattg ttttttgttt
     8161 aagtgtatct atgtttctct atttttttgg ggaaaggctc acgtctcttt catttatagg
     8221 agttaggaga gttatcactt ctaactcccg ataactcctt caaatattta gtaactgtct
     8281 gcattgtctt tgaggatgtt tttctgagga gcatagcggc tatgtggcga ataaagagag
     8341 gaagacagac cgaaaagaag ctgaataaaa tctttttaag caaaattaaa acagagattt
     8401 gatatacttt aaacagaaca ccctgcaaac tccggcttac tctgtccggc agtttgcagg
     8461 gtgtctgctt ggttttctca cgtgtacgta gctctttacg ccacgaacgg aagtcgatgc
     8521 catagcaatt tttcataata agactttcca tatttttgca aatgtccata ctgcctttgg
     8581 ctgaaacaat ttatataagt aattgaagtt tcgtaagtga gtatgcctgc tgataaatgg
     8641 gaatttatcg cacagagcgc gaagcctgct ctcataacct atggagagca cgagtgaaag
     8701 cttgtggatt tttatctaaa acataggtat tcctttgctc ttctcccttt gtttgtctgc
     8761 tgtggcatag ggaatttatg acgcctaacg gccatgaaca accctgcttt cgaccataaa
     8821 gcgatcgctt gacgaccgta agcagagttg ttcatggccg ttaggcgtca ctaactccag
     8881 agctattacg gatgaagtac gtagcccgaa cctattgcgc acaaggcgca aacgtattat
     8941 acaacggtgt aaaagacatt agagtgcatt attcatagtc ggcctttgat tcccgataac
     9001 tcctactatg cccctacagt ccaactccat atccgttgac ttcacagtaa ggacaagccc
     9061 gaaaatgcag gaaaaccgaa cctgccgatt catgtaatct gcatgctgta ttatggtagg
     9121 ggatagcagc ttactgcaaa actcaagcgt ttcaggcagg tggaagcaaa ttttgcttcc
     9181 accttttcag gttgcttcca ccgcagggca aatgccgatg gacaggggga tgcaggaggt
     9241 gggtggaagt gtggaagcaa agtgatggaa aattaatttg gcattcacac aataataacc
     9301 gtatatttgt agcatggctg tctgcctcct cttaaattca gataaagagg aggtagacaa
     9361 atgcttgcta tgagaaacac ataaatggtt ataaccaagt gatgaaacaa ttaattgcat
     9421 gttgcggact ggattgcgaa aattgcgccg cccgtatagc cactgtcaat aatgacgatg
     9481 agctgagaga gaaaaccgcc aaagagtgga gtgtgctgaa caatacgccg gaaattacgg
     9541 cagaaaccat ccattgtatg gggtgccgtg cagacggggt gaagtttgcc tattgcagcg
     9601 attattgtgc tatccgcaaa tgtgtgtacg aaaaaggttt caatacttgc ggtgactgta
     9661 aggaactgga aacttgccag gtggtaggtg ccgttcttca gcatgcaccc ggtgcaaagg
     9721 aaaatcttta ttaaccgtaa attctttgat taaataaaat attgcttatc tttgcagtat
     9781 gacaaagaca tttaaatcgg atttggtttt gtaaacaatc tgtgttcctt gcacagattg
     9841 tccctttcgt ttactctcgg ataacttctt tcgagagtgt ttctctattg ttataattaa
     9901 agtttaatcc gcgtattatg ctgaaggtat tgtgatactt tccgtatatg caaaatatag
     9961 taagaaaatg agtaacgaaa ataaaaccat ccacgatttc gaacttagtt taatctgtga
    10021 ctttttctcc aatatggaac ggcaaggccc tggcagtccc gaagcgacgt tgaaggcatt
    10081 gagctttgta gacggcctta ctgataaatc ccttattgcc gatataggtt gtggaacggg
    10141 tggccagaca atagtagtag ccgggcatgt gccggggcgg attaccggaa ttgacctttt
    10201 ccccggcttt attgacatct tcaaccgtaa tgcaaggcag ttgggcttgc aggacagagt
    10261 aaaaggaatt gtcggttcaa tggatgccct ccctttcggt gaggaggagc tggatatgat
    10321 ttggtgtgaa ggtgctatct ataacatcgg ctttgaacgt ggcttgaagg agtggcgtaa
    10381 atatctgaaa ccgggagggt atattgccgt atccgagagt tcatggttta cggacgaacg
    10441 tcctgcggaa atcaatgact tctggatgga cgcctattct gaaatggata cacttcccaa
    10501 tcaggtagcc aagttgtaca aggcgggtta tctccccgtt gctacattca ttctgccgga
    10561 gaattgctgg acagagcatt actttgcttc aaaggttgcg gctcaggaga ttttccgtaa
    10621 gaaatatgcc ggtaataaaa ttgccgaaga gttcagctca ctccaaatga ttgaggatga
    10681 actatacggc aaatataagg aattctacgg ttatgtgttt tttattgcta agaaggtagg
    10741 ttgatggcag acttctctta ttgaggaatg cgggtattct catggcagaa tatccgcatt
    10801 ttgtgttttg agtggatttt attgttttga ggatgtgcgg aacttctgag gaggtattcc
    10861 cgtatgacgt ttaaagaatt tgttgaagaa ggccgcatta ttaaaaccta gactcacggc
    10921 tatatccttt atcggagtgt tggcggtaca aagttgtgct ttggcatcca tgatgatagt
    10981 attgttgatg atttccatgg ctgtatgtcc tgattccttt ttgacaaggc ggcaaagagc
    11041 tgccggtctc atattcattt tcaatgcata ataggacact tgatgctccc ggacatagtc
    11101 tgtgtgtacc aatcggataa aaatgcggta ttggttgaaa tgcctgctgc ccggagtctc
    11161 ttttattcta gggcgttccg gacagagttc ggatatacct tgtaacagat aggtcagtag
    11221 agtttgcaat gaaactagac ttgaggggct ttctgttctt tggtagaggt gtgacaaata
    11281 ggtcatgaac tcggcataaa gctggaagtc cgttttcgat agaggaaaaa tatagtgttt
    11341 gcctataatg tgaaacttat ccatcatgac cttgccggcc cctgaactct ggataagttg
    11401 ttgggaaaat atgacgacat atatttcagc atcgtctgac gtgtgtagca attgtacgaa
    11461 ggtctcggga ggaataacta ggagggtgtt agcttcaacc ctgaattgag tatggtttat
    11521 gatggttttc agaactcctt tggtgcatag agcgaagata ctggccttgg tgtggtatgg
    11581 cttttccact agcggattca gttcattggt tgtgatatga ttgcaggcaa tgaactcggc
    11641 atttatattg aattcggata tattcatgtt ggagatttta agacacaaaa atgggggata
    11701 ataatgtata aatgacagag ataacagtta aaatcaatat tacgctcaat ttgtctctgt
    11761 taaataaggt aaagttgtga ataatagaat atatacatgc taaaacggaa tattgattta
    11821 taagggtttg tttgtggcat aagcatttta gcccgaactt tgctccttgt atgataaaac
    11881 aattctgatg aatccgaatg ttcctcaaga agtacgtata ataaatgcca tctccgagca
    11941 gttgttcaac tcatggcccg tcagcattat tatgattgat ttggaagatt gtatctggcg
    12001 tctgaatcag caggtgatga atgaactcca tttgaatgag tatgtgatag ggcggcgtat
    12061 cactgactta ttggaagtgg tatgtgataa aaagaatgtg ttagaagacc ttttgctgca
    12121 acttcgggag agggatgtgc ggattattcc cttagatatc aattgcttta tacgtgaatt
    12181 gaagagtggt atcagttttc tgatacaagg tgctatggtg ggaattcatg aagatggaca
    12241 attggtgagg attgtactct atttcaggaa tgtgttggaa gaacggacac agaagcattt
    12301 gctgaatatt gcgctgagcc gcacccagat atttcaatgg tctttcgaca tggaacataa
    12361 tctgatgatt atagaaccgc gtta
//
