LOCUS       c00091_gnlPro..        16545 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|EPHPABLM_91.
ACCESSION   c00091_gnlPro..
VERSION     c00091_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-07 20:56:40
            Original ID  :: gnl|Prokka|EPHPABLM_91
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 16545
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..16545
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[6382:12845]"
                     /cutoff="10000"
                     /detection_rule="(minimum(1, [PFOR_II, POR, POR_N]) and
                     minimum(2, [CoA_binding, CoA_binding_2, Ligase_CoA, PTAC,
                     Succ_CoA_lig]) and not (Gly_radical_scatole or Gly_radical
                     or Gly_430_pcre or Gly_8-9_TMA))"
                     /neighbourhood="10000"
                     /product="OD_unknown"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      6383..12845
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(1, [PFOR_II, POR, POR_N]) and
                     minimum(2, [CoA_binding, CoA_binding_2, Ligase_CoA, PTAC,
                     Succ_CoA_lig]) and not (Gly_radical_scatole or Gly_radical
                     or Gly_430_pcre or Gly_8-9_TMA))"
                     /neighbourhood="10000"
                     /product="OD_unknown"
                     /protocluster_number="1"
     cand_cluster    1..16545
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(minimum(1, [PFOR_II, POR, POR_N]) and
                     minimum(2, [CoA_binding, CoA_binding_2, Ligase_CoA, PTAC,
                     Succ_CoA_lig]) and not (Gly_radical_scatole or Gly_radical
                     or Gly_430_pcre or Gly_8-9_TMA))"
                     /kind="single"
                     /product="OD_unknown"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..16545
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="OD_unknown"
                     /region_number="1"
                     /rules="(minimum(1, [PFOR_II, POR, POR_N]) and minimum(2,
                     [CoA_binding, CoA_binding_2, Ligase_CoA, PTAC,
                     Succ_CoA_lig]) and not (Gly_radical_scatole or Gly_radical
                     or Gly_430_pcre or Gly_8-9_TMA))"
                     /tool="gutsmash"
     CDS             104..328
                     /locus_tag="ctg91_1"
                     /transl_table=11
                     /translation="MKSCEMHLVLVLSDHVNVGKDPLYRPPKTQKAEEGRTTQTTVYPH
                     VKASGKFPGKNPRAQKAHLYAFKETFLEK"
     CDS             complement(569..2299)
                     /locus_tag="ctg91_2"
                     /transl_table=11
                     /translation="MRRVYSIALLLLVALGLSATTKEVKLKLVETSDIHGNFFPYNFIE
                     QREWGGSLARVYSFVQEERRAYGDNLLLLDNGDILQGQPSAYYYNFMDTVSTHIASAMM
                     NYIGYNAGNMGNHDVEAGHAVFDRWIKQCDFPILGANIIRTSDRETYLKPYEVFERDGV
                     KIVVLGMITPAIPVWLPETLWQGLYFADMEETARKWMKIIQEKEKPDVVVGIFHAGNEA
                     RTMSGQYREDASMEVAQRIPGFDVVMMGHDHRRYCGKVANIEGDSVLLINPASNGRVVG
                     SVDVVLKMEHGKVLDKQVSGVLTDVDKLEPSEEFMEKFAPQYKAVNDFVSEKVGTFTES
                     IATRPAYFGPSAFIDFIHSLQLELTGADVSFAAPLSFDAKIDKGDITISDMFSLYKYEN
                     MLYTMNLTGAEIKGFLEESYAMWTNRMKSPDDHVLLLKERKKGQENYVSFVNFSFNFDS
                     AAGIIYTVDVTKPEGEKITILKMADNRPFDENKTYKVALNSYRGNGGGELLTKGAGIPQ
                     DELKSRIIHSTDKDLRYYMIQYIKEKGVLSPQPLNQWQMIPQDWTRPAAERDCKFLFGE
                     "
     CDS             complement(2318..4744)
                     /locus_tag="ctg91_3"
                     /transl_table=11
                     /translation="MKTYLFLLLFVFQAFSLSSQISLKGYNQEKIDPSLFEGRWKARWI
                     SYPGEAPNVYGVYHFRKSFDLEVVPSRFIVHVSADNRYKLYVNGKLVSLGPARGDIYNW
                     SFETVDLAPYLRKGKNTLASVVWNYAERKPVAQISYDQTGFILQGNTGHEAVVNTDTTW
                     VCLRNKAYAPWTEWQVLGYYVAGPGEELEASAYPWGWEQPDYDDRKWEKAVRGMEGATK
                     GSRDYPGRLLVPSPIPPMDSRIERLAKLRRSEGIECPQGFPYWPKALTIPANTEVRLLL
                     DNDYLTTGYFSLAFSKGKEAEIHIGYSEALYKQEEESTTKSYALNGKGHRDELTDKQFI
                     GYGDKILADGGDNRLFTSLWWRTWRYVELKVKTASEPLVIEDMYGTFSAYPFRNETTFS
                     APGHEELGRMLEIGWRTARLCANETYMDCPYYEQLQYFGDTRIQAMISMYNTSDPYMVK
                     NAIEQGRQSMVAEGITMSRYPSSVHQFISSYSLWWICMGHDYWMYRGDEAYMKTLLPAY
                     RQVLSWYEQWLKPDYSLSYVPHWFFVDWAAGFDYGEPIREKEGSSALQDLMYIMTLEFA
                     VEMEQAIGLPAMADHYRKIATEMRKTIRPKYWDAARNLFADTQDHRGYSQHVNALAILT
                     GVTKGEEAVKVMNQTLADTSLIQCTIYFRYYLNQALKVSGLGDQFLDNLQIWRDQMALG
                     LTTWAEMPEPSRSDCHAWGASPNIEFYRILLGIDSDAPGFRKIRIAPSLGKLKEVSGTI
                     PHPLGSVTAAYKLDERGEGTARLVLPEGTTGIFIWDGKEIPLKPGEQVISLSSRH"
     CDS             complement(4866..5654)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_7"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg91_4"
                     /sec_met_domain="Fer4_7 (E-value: 5.3e-11, bitscore: 32.9,
                     seeds: 208, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4 (E-value: 5.6e-11, bitscore: 31.8,
                     seeds: 528, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 1.1e-05, bitscore: 15.7,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKYSNIHLIYFSPTHTSAKIVYAIAEGMGATSMSESDVTCESLDM
                     EEYIDDELTIIAAPVYGGRVAETAMERFRMFRSAHHAPVVPVVLYGNRDYEDALKELCD
                     LVSEQGFVPVAAGAFIGEHSFSRKGMPIAEGRPDESDLNQATEFGKKIIEELEKVSCVE
                     CLSALEVKGNFPYRVKGPSTPQAPVTDNDLCTQCEYCVDVCPTHAISLADEGMYSDPNL
                     CIKCCACVKECPEGARTFDTPYTAMLHKNFSARREPEIFF"
     CDS             complement(5660..6235)
                     /locus_tag="ctg91_5"
                     /transl_table=11
                     /translation="MRFDENFNVSLSLNPKREMIKVMKKYLLASLLALLAFVGKAQEDN
                     SDIVKVGDTMPSFTIVSDNGSKLQSASLKGKVILVNFFATWCPPCQKELAAVQQTLWPK
                     YKNNKDFVLLVIGREHSDADLQKYNEKKGFDFPLYPDKDRAIFGAFAKNLIPRGYLVGK
                     DGKIIYTSKGYTDEEFAELMTKIEGALK"
     CDS             complement(6383..6964)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     OD_unknown: POR"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg91_6"
                     /sec_met_domain="POR (E-value: 2.2e-43, bitscore: 138.1,
                     seeds: 86, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKTDIILSGVGGQGILSIAAVIGEAALKEGLYMKQAEVHGMSQRG
                     GDVQSNLRLSDEPIASDLIPKGHADLIISLEPMESLRYLPYLKKEGWLVTNSRPFVNIP
                     NYPEIEKVNAELDKLPHKVVLDVEEIAKEAGSVRAANIVMLGAATPFIGIEYDKIEAGI
                     RQIFGRKGEDIVNMNLKALKAGYDLAQSLR"
     CDS             complement(6961..8562)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     OD_unknown: POR_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg91_7"
                     /sec_met_domain="POR_N (E-value: 1.4e-14, bitscore: 44.1,
                     seeds: 31, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 8.5e-19, bitscore:
                     57.6, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEKHLFLGDEAIAQAAIDAGISGVYAYPGTPSTEITEYIQGSPVT
                     KERGIHCRWSANEKTAMEAALGMCYAGKRALCCMKHVGLNVAADCFMNAAMSGINGGMI
                     ILTADDPSMHSSQNEQDNRIYGNFAMIPMFEPSSQQEAYDMVYHGFELSEKLGYPILLR
                     VTTRMAHSRAGVVTSPLKPENRMNCPEDGRQRFILLPALARKRFKSLLASQEAFTEASE
                     NSAYNKYFDAPNKDLGIITTGIAFNYLSENYPDGFEHPVLKISQYPLPRKQVEKIVGEC
                     KEILVLEEGYPVVEEQLKGFLAKGVTVHGRLDGTLQRDGELTPDAVGKALGKEIQSYYA
                     IPEVVEQRPPALCQGCGHRDMYEALNEVIAEYNGTAKVFGDIGCYTLGALPPFRAIDSC
                     IDMGASITMAKGASDAGVFPAISVIGDSTFTHSGMTGLLDCVNENTNITIVISDNETTA
                     MTGGQDSAGTGRLESICAGIGVDPAHIRVMVPLKKNYEEMKAIIREEIEYKGVSVLIPR
                     RECIQTLTRKKKASKK"
     CDS             complement(8667..9716)
                     /locus_tag="ctg91_8"
                     /transl_table=11
                     /translation="MDLNKQILSRRPIIIALIAILVVLIGGGGFWVYRLAWAPNFKPDK
                     TVYVYIDDKKDFDDLCRQLRDSANCLRIGSFKQLSGLLKYPASMRTGRYAVKPGMSNLT
                     LLNDLRRGHQVAARVTFNNIRFKEDLAERISDQLMFGKENLLRLLNDSVYCDSLGFTPE
                     TIDALFIPNTYEIYWNISADKFIRRMKREYDAFWTPERLKKAEEIGLTPVEVSILASIV
                     EEETAASDEYPIVAGLYINRLHAGIPLQADPTVKFAVGDFSLQRILFEHLEIDSPYNTY
                     KYAGLPPGPLRIPTIKGLNSVLNHTKHKYLYMCAKEDFSGRHNFAVTLAEHNRNANRYR
                     AELNRRRIR"
     CDS             10082..10696
                     /locus_tag="ctg91_9"
                     /transl_table=11
                     /translation="MTIAFIRTYNNKQNSEVQEAVIREFAESQKIEIGKWAKEVGNSPR
                     ANRRLESIVKSLSPGDEILVSDISRVSRKMIEIIHIILLCIERKVTLRSVSDGYVFEDN
                     IDSKTLAFTFGLVSEIERKLVSIRTKEALALIRSKGVVLGRPKGSQQMGRLEPYKEQIE
                     KDLKDPSLTYAQIAEKYNVSLSSFKRFLKEYLPDKKKKKKK"
     CDS             complement(10785..12845)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     OD_unknown: Succ_CoA_lig"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     OD_unknown: CoA_binding_2"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg91_10"
                     /sec_met_domain="Succ_CoA_lig (E-value: 5.7e-37, bitscore:
                     116.4, seeds: 149, tool: rule-based-clusters)"
                     /sec_met_domain="CoA_binding_2 (E-value: 1.5e-21, bitscore:
                     66.9, seeds: 225, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MINRELINPQSIVVVGGSNNVHKPGGRIVRNLLDGKYKGELCVVN
                     AKETDVQGVKSYPSVHDIPGTELAIISIPSKSCPEVMEVLARQKGVKAFIVISAGFGEE
                     THEGGILEQQMLDVVNEAGASLIGPNCIGLMNMNYHGVFTQPIPEFHPDGVDFISSSGG
                     TALFIIESALTKGLRFSSVWSVGNSKQNGVEDILEYMDRNFDPVLDSKIKMLYIEQIKQ
                     PDKLLYHASSLIRKGCKIAAIKAGSTESGKRAASSHTGAIASSDSAVEALFRKAGIVRC
                     FSREELTTVASIFTLKDVKGKNCAIVTHAGGPAVMLADALSKGRLNVPSLEGPIADELK
                     SKLYPGAAVGNPIDIIGTGTPEHLATAIDFCENRFDNVDLMMVIFGSPGLVKLYDTYEV
                     LHKKMEECKKPIFPILPSIVTAGPEVKSFVKKGHVNFSDEVTLGTALSRVINTPKPMST
                     DIQLYGVDVPEVRRIIDRLPGSGYLNPEEVRTLLRAANIPLVEEYASDDRDALLAFAKK
                     VKYPVVAKVVGPVHKSDIGGVALNIRGEEHLLFEYERMMRLPGVTGIMVQPMLKGQELF
                     LGAKYEDRFGHVVLCGLGGIFVEVLKDVSYGLAPLSYDETYSMIRSLRGYPIIKGTRGQ
                     KGIDEQQYADIIVRLSTLLRFASEIKEMDINPLVATDRGLFAVDARIRIEK"
     CDS             complement(12925..13677)
                     /locus_tag="ctg91_11"
                     /transl_table=11
                     /translation="MCGTCGCGEHHHHHDHAHEHSHGHEHHHHPDEGIVINLEQDILQR
                     NNLLAERNRGYFEAKNLFCLNLMSSPGSGKTTLLEETIRRLKAKRPIYVIEGDQQTSND
                     ADRIAALEIPVFQVNTGTGCHLEADMVNHAVKHLNPKEGAILFIENVGNLVCPAMFDLG
                     ESKKVVIVSTTEGDDKPLKYPHIFQEADICVINKIDLAPYLNTKVEVLRENALKVNHHL
                     QIFEVSATKGDGMDAWCDWLQTESAKCK"
     CDS             complement(13707..14054)
                     /locus_tag="ctg91_12"
                     /transl_table=11
                     /translation="MHELSIARSIVELVEEQADNRGASVVEELELEIGHLSGVEIQTLA
                     FALDSAIKGSKLEKARIIRHYIEGEGQCSDCETIFPMNALFSPCPHCGSYLVKILKGKE
                     LRVKSIVIKKE"
     CDS             complement(14067..16349)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_M22"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg91_13"
                     /sec_met_domain="Peptidase_M22 (E-value: 1.4e-09, bitscore:
                     27.8, seeds: 111, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAKNKVYALIIQGLVQGVGFRPFIYRIAKDLGMKGCVENMNNGVR
                     ILVAATPDDRDLLISRIRTEHPRVAYIHRISYTSTEMDEDDFDDFTITPSHSESDEVTQ
                     VSPDIAVCADCMRDRTTQPHRIGYPFINCTHCGPRFSIIRDLPYDRSQTTMGGFLMCPD
                     CEKEYTNVIDRRFHAQPVACNHCGPTYYATYNEETYIYYETLLKLTSRLLLGGEVIAAK
                     GIGGYHLICDASNERAVARLREIKQRDTKPFAVMFRDLEHLQVYTVTEPMEERCLVSWR
                     RPIVLLRQRSRLASGINPGMHTLGCMLSYMPIHYDWFARTGIPALVMTSGNLSDLPIAI
                     TPEDAEAQLAGKVAILLHHNRPIHNRVDDSVLQVCGGQPCLIRRSRGYVPEPFFTDTNV
                     EGIMAFGAEKVNTFALGKGETILQSQYIGDLKNWETFRFYTESMEQFRHLFRFNPQRLV
                     CDLHPDYLSSQEAERISKSLSLPLLKVQHHHAHAAACMLEHGLNEPVLAIVMDGTGLGD
                     DGKVWGGEFFFCDRAKYRRLSHFEYVPLPGGDKAAEEPWRMVVAYLWHYFKDEPSGIPY
                     PADFVERIGTERIAMLERMMEKGVNTPYTSSAGRLFDAVASLLGICDVSSHQAEAPVLL
                     EQAAMGERNAYAYPVSAEGEEISFYSLFEALLHDKTNEVPVSLISARFHTTLASLFVQK
                     ARLLIKRTKATQVVISGGCFQNKLLTESMRRQFIMAGVPVYIPSRIPCNDGGIAVGQLT
                     IASVTPF"
ORIGIN
        1 cacttgaaac aagtgctcca cgagtacatt cgcacgtaat aaaaacgatg aacatcatct
       61 tggccccgat aggaaatcac acagaaaaaa cggcttttag ctcatgaaat catgcgaaat
      121 gcacttggtt ttagtgcttt cggatcacgt aaacgtgggt aaggacccat tatatcgccc
      181 cccaaagacc caaaaagccg aagagggaag aaccacacaa acaactgtat atccacatgt
      241 taaggcatca ggaaaattcc ccggtaaaaa tcctagggcg caaaaggcgc atctttacgc
      301 tttcaaagaa acatttttag aaaaataata tttacatcac tctacagaca agaggggtat
      361 aaacgttatt tacagaaaaa gttttagaaa catacgtaaa gatgcgccct ttgcgcccta
      421 acctatcagc aacatcccta atacgggata caaaaaagtc aatgggacac ggccgtaaag
      481 tcattgagaa accatctcta ttccattgac tttaccaccg tttcccattg agatactatc
      541 gcaaaccaga cacttcaagg acggaaactc attccccgaa aagaaactta caatcccgtt
      601 cggccgccgg tctcgtccaa tcctgcggga tcatttgcca ttggtttaaa ggttgtgggc
      661 taagtacgcc cttttccttt atatattgaa tcatataata acggaggtct ttatcggtcg
      721 aatgaatgat acgactcttt aactcgtctt ggggaatacc ggcccctttc gtcaataact
      781 cacctcctcc attacctcgg taagagttga gagctacttt atacgtttta ttctcgtcga
      841 aaggcctgtt atccgccatt ttcaagatcg taatcttctc accctctggt ttcgttacgt
      901 ccacggtgta aatgatacca gctgcggagt caaagttaaa actgaagttg acgaatgaga
      961 cataattctc ctgtcctttc tttctctctt tcaataataa gacatgatcg tccggagatt
     1021 tcatccggtt ggtccacata gcgtatgatt cctccaagaa acctttgatc tcggctcccg
     1081 tcaaattcat cgtataaagc atattctcat atttgtaaag actgaacata tcgctgatcg
     1141 tgatatcccc tttatctatt tttgcgtcaa aggataacgg ggcggcaaaa gagacgtccg
     1201 caccagtcaa ctccaattgt aaagagtgaa taaaatcaat aaaagcggat ggcccaaagt
     1261 aagcgggacg ggtcgcgata ctctccgtaa aagttcccac cttctcggag acaaaatcat
     1321 tcaccgcttt gtattgcgga gcgaatttct ccataaactc ctcgctaggc tccaacttat
     1381 ccacatccgt caaaacaccc gatacttgtt tatccaaaac ctttccatgc tccatcttta
     1441 acacgacatc aacggaaccg actacacgcc cattacttgc cggatttatc agcaacacgg
     1501 aatctccctc gatattcgcc accttaccac aataccggcg atgatcatgc cccatcataa
     1561 ccacatcgaa gcccggaatg cgctgggcaa cctccatcga cgcatcctca cggtactggc
     1621 cggacatggt acgagcctcg tttcccgcat gaaagatacc taccacaaca tccggcttct
     1681 ccttctcctg aatgatcttc atccatttac gggccgtctc ttccatatcg gcgaaataaa
     1741 gaccttgcca cagagtctcc ggcaaccata caggaatagc cggagtaatc atccccagta
     1801 caacgatctt cacaccgtca cgctcaaata cctcataggg ctttaaatag gtctcccggt
     1861 cggaggtacg gataatattg gcacccaaga ttgggaaatc acattgtttg atccaacgat
     1921 cgaaaacggc atggccagcc tctacatcat ggttacccat atttcccgca ttgtacccga
     1981 tataattcat catggcggaa gctatatgcg tagagaccgt atccatgaaa ttataataat
     2041 acgccgaagg ttgtccttgc aagatatcgc cattatccaa tagcaaaagg ttatcgccat
     2101 acgcccggcg ttcttcttgc acgaacgaat atacccgtgc cagacttcct ccccactccc
     2161 gctgctcgat aaaattatac gggaagaagt ttccatggat atcactggtt tccactaatt
     2221 tcaactttac ttccttcgtt gtcgccgaca gaccgagagc gaccagcagc aataaggcaa
     2281 ttgaataaac tcgtctcata tcaggatttt agatagatta atgacgcgaa gataacgaaa
     2341 taacctgttc gcccggtttc aacgggattt cttttccatc ccagataaat atacccgtag
     2401 taccttccgg caagaccaga cgggcggttc cctcacctct ctcatccaat ttataagcgg
     2461 cggtcacgct tccaagcgga tgtgggatcg taccggaaac ctccttcagt tttcccaaag
     2521 acggagcgat ccgtatcttc ctaaatccgg gagcatcgct atctatcccc aacaagatcc
     2581 ggtaaaactc gatattcgga ctggctcccc aagcatggca atcagaacgg gatggctccg
     2641 gcatctctgc ccatgtggtc aatcccaacg ccatctgatc ccgccatatt tgtaagttat
     2701 ccaagaactg atcccctaaa ccggaaactt tcaacgcttg attcaagtaa taacggaaat
     2761 agatcgtaca ctggatcaag ctcgtatccg ccaaggtttg gttcatcacc tttacggcct
     2821 cctccccttt cgtaacccca gtcaagatcg ccaaggcgtt cacatgctgg gaatagccac
     2881 gatgatcctg cgtatcggcg aatagattac gggcagcgtc ccaatatttc gggcggatcg
     2941 tcttacgcat ctcggtagcg atcttccggt aatgatccgc catggcaggg aggccgatcg
     3001 cttgttccat ctccaccgca aactccaagg tcattatata catcaaatct tggagcgccg
     3061 agcttccctc tttctcccgt atcggctcgc cataatcaaa accggccgcc caatccacga
     3121 agaaccaatg aggaacgtac gacaaactat aatccggctt caaccattgc tcgtaccacg
     3181 acaaaacctg acggtaagcg ggaagcaagg tcttcatgta tgcctcatcc ccacggtaca
     3241 tccaataatc gtgccccata caaatccacc agagagagta cgaggatata aactgatgta
     3301 cgctagacgg atatcggctc atcgtaatcc cttccgccac catggactgc cgtccttgct
     3361 ctatggcatt cttcaccata taagggtctg atgtattata catggaaatc attgcctgta
     3421 tgcgtgtatc cccgaaatat tgcagttgct cgtaatacgg gcagtccata tacgtctcat
     3481 tggcgcacag acgggcggta cgccatccta tctcgagcat acggcccagc tcctcatgtc
     3541 ccggagcgga gaaagtggtc tcgttacgga aaggataggc agagaaagtc ccatacatat
     3601 cctcgatcac caaaggctcg gaagccgtct tcactttcaa ctccacatat ctccatgtac
     3661 gccaccacag ggaggtgaag agacgattat ctcccccatc agccagtatc ttatccccgt
     3721 acccgataaa ctgcttatcc gtcaactcgt cccgatgtcc cttgccattc aacgcatacg
     3781 atttagtggt cgattcctct tcttgcttat agagggcttc cgaataaccg atatggatct
     3841 cggcctcctt tcctttgctg aaggctaagg agaaataacc cgtcgtcaag taatcattat
     3901 ccagaagcaa gcggacctct gtattcgccg ggatcgtcaa agcttttggc cagtaaggaa
     3961 atccttgcgg gcattcgatc ccttccgacc ggcggagctt ggccagacgc tcgatccggc
     4021 tgtccatcgg aggtatcggg ctaggaacca gcaaccgtcc cgggtaatct ctcgatcctt
     4081 tcgtggcacc ttccatgccc cgtacggcct tctcccattt cctgtcgtcg taatccggtt
     4141 gttcccagcc ccaaggataa gcggaggctt ccagttcctc acccgggcca gccacgtaat
     4201 accccaatac ctgccattcg gtccaaggag catacgcctt attacgcagg cagacccaag
     4261 tggtatccgt atttaccacc gcctcatgcc ccgtattgcc ttgcaggata aaacccgtct
     4321 gatcgtaact gatctgggca acaggtttcc gctcggcata attccagaca acggaggcca
     4381 gcgtattctt ccctttcctc agataaggag ccagatccac cgtctcgaaa ctccagttat
     4441 agatatcccc acgggccggg cccaaggata ccaatttccc gtttacatat aatttataac
     4501 ggttatcggc ggaaacatgg acgataaacc gggaaggaac cacctccaga tcgaacgatt
     4561 tacgaaaatg atagacccca tatacattcg gggcctcacc cgggtaggag atccaacggg
     4621 ctttccatcg tccctcgaaa agagaaggat cgatcttctc ctgattatac cctttcaggc
     4681 taatctggga ggaaagggaa aaggcttgaa acacaaaaag caaaaggaat aaataggttt
     4741 tcatacaaac acggtattat ttgagattaa cgatccgaac aaaggtacaa aaaaagagaa
     4801 agcgccaaaa gaacttttgc cttttgacgc tttccctcac aatataccgg atgcccggtc
     4861 ctccattaga agaatatctc cggctccctg cgtgcgctaa agttcttatg gagcatcgcc
     4921 gtgtaaggag tatcgaaagt acgtgcgccc tcgggacact ctttcacgca ggcgcaacat
     4981 ttgatacata ggttcgggtc gctatacata ccctcgtctg ccaaggatat cgcatgtgta
     5041 ggacacacat ccacgcaata ctcacattgc gtacataaat cgttatccgt aacaggagct
     5101 tgaggagtgg aagggccttt cacccgatac gggaaattac ctttcacctc caaggcggac
     5161 aagcattcca cgcaggaaac cttctccagc tcctcgataa tctttttccc gaattccgta
     5221 gcctgattaa gatccgactc gtccggacgc ccctcggcaa tgggcatccc cttgcggctg
     5281 aaagaatgct cgccgataaa cgctccggca gccacaggta cgaacccctg ctccgacact
     5341 aaatcacaga gctctttcaa ggcatcctca taatcccggt tcccatacag taccacgggg
     5401 actaccggcg catggtgggc agaacggaac atgcgaaaac gttccatggc agtctccgcc
     5461 acacggccac cgtatacagg agcggctata atcgtcagct catcatcaat atactcttcc
     5521 atatccagac tctcacaagt gacatcagac tcggacatcg aagtggcacc cattccttcc
     5581 gctatcgcgt aaacgatctt ggcggacgtg tgtgtcggag aaaaataaat taaatgtatg
     5641 ttactatatt tcatgattct tattttaacg caccctctat tttagtcatt aactcagcaa
     5701 attcctcatc ggtatagcct ttgctcgtat aaatgatctt cccgtctttt ccgaccaaat
     5761 agccacgagg gatcaagttc ttggcgaaag cgccgaaaat agcccggtcc ttatcgggat
     5821 acaaaggaaa atcgaagcct tttttctcgt tatatttctg tagatcggca tcggaatgct
     5881 cacgcccgat caccaagaga acgaagtcct tgttgttctt gtatttcggc cagagggttt
     5941 gttggacagc ggccaattct ttttggcagg gaggacacca agtggcgaag aaattcacga
     6001 ggatcacttt tccctttaac gaagcggact gcaacttact cccgttgtcg gaaacaatcg
     6061 taaatgacgg catggtatca ccgaccttca cgatatcgga attatcctcc tgagctttgc
     6121 ctacgaaagc caataacgct agtaaactag ccaataaata cttcttcata accttaatca
     6181 tttctcgttt aggattcagc gacaaagata cattaaaatt ctcatcaaac cgcataattc
     6241 taaggcttac gaaagttcta cgatgctgta cctacccctc gacagctctt ctaaaagttc
     6301 tagggggtta gatgttaaaa aaaacgtacg tgaaacccgg agatgtcacg tacgctgata
     6361 ccatgcaaac ccggagaaag atttaccgca gactttgcgc taagtcataa ccggctttca
     6421 acgcctttag gttcatatta actatatcct cgcccttacg accgaatatc tgacggattc
     6481 ccgcctcgat cttatcatac tcgatcccga taaatggggt agctgccccc aacatcacga
     6541 tattggcggc acggacagaa cccgcttcct tggcgatctc ctccacgtcc aatacgacct
     6601 tgtgagggag cttgtccaac tcggcgttca ctttctcgat ctccggatag ttcgggatgt
     6661 tcacgaacgg acgggagttt gtcaccagcc aaccctcttt cttcaggtaa ggcagataac
     6721 gcaagctctc catcggttcc aaggagatga tcaaatcggc gtggcccttc gggatcaagt
     6781 ccgaggcgat cggctcgtcg gaaagacgca ggttagactg cacgtctccc ccccgttgac
     6841 tcataccgtg tacttccgct tgcttcatat acagaccttc ttttaaggcg gcttctccaa
     6901 taacggcggc gatagaaagg ataccctgtc ctcctacacc tgatagtata atatctgttt
     6961 tcatttcttg cttgcttttt tctttctggt taatgtctgg atacactcac ggcgggggat
     7021 caatacggat acgcccttgt actcgatctc ctcgcggatg atagctttca tctcctcata
     7081 gttctttttc aaaggaacca tcacacggat gtgagccggg tccacaccga taccggcgca
     7141 gatagactcc agacgtcctg ttccggcgga atcctgcccc ccggtcatgg ccgttgtctc
     7201 attatcggag ataacgatgg tgatattcgt gttctcgttc acgcaatcca gcaaaccagt
     7261 cataccggaa tgggtaaacg tagaatcgcc gatcacggag atagccggga atacacccgc
     7321 gtcggaagcg cccttcgcca tcgtgatgga ggcgcccata tcgatacaag aatcgatcgc
     7381 acggaaagga ggcaaagctc ccaaggtata acagccgata tcgccaaaca ccttagccgt
     7441 accgttatac tcggcgatca cctcgttcaa ggcctcatac atatcccggt gtccacaacc
     7501 ttggcacaat gcgggcggac gttgctcaac cacctcgggg atcgcataat agctctggat
     7561 ctccttaccc aaggctttgc ctaccgcatc tggcgtaagc tcaccgtcac gctgaagcgt
     7621 accgtccaga cggccatgaa ccgtcacgcc tttcgccaag aagcctttta attgctcttc
     7681 aacgaccgga tatccctctt ccaacaccaa gatctcctta cactcgccaa cgatcttctc
     7741 cacttgcttt ctcggaagcg gatactggga gatcttcaat acgggatgct cgaaaccgtc
     7801 cggataattc tcggaaagat aattgaaagc gatacccgtc gtgatgatac ccaagtcttt
     7861 attcggggca tcgaaatact tattatacgc ggaattctcg gaagcttccg tgaaagcctc
     7921 ttgagacgcc agcaaactct tgaaacgttt acgagccaat gccgggagta agataaaacg
     7981 ttgacgaccg tcttccggac aattcatccg gttctccggc ttcaacgggc tggttacgac
     8041 accggcacga gaatgcgcca tacgggtcgt tacacgcagc aagataggat accctaattt
     8101 ctcggataac tcgaatccat gatataccat atcataagcc tcttgctggc tggatggctc
     8161 aaacatcggg atcatggcga aattgccata aatacggttg tcttgctcat tctgggaaga
     8221 gtgcatggat gggtcgtcgg ccgtaaggat gatcatacct ccgttgatac cgctcatagc
     8281 ggcgttcata aagcaatcgg cggctacatt caaacccacg tgcttcatgc agcaaagcgc
     8341 acgtttaccg gcatagcaca tacccaaagc ggcttccatg gcggttttct cattcgcgct
     8401 ccagcgacaa tggatacctc tttccttcgt taccggagaa ccttggatat attctgtgat
     8461 ttcagtagaa ggggttcccg ggtatgcgta taccccggag attccagcgt ctatagcggc
     8521 ttgcgctatg gcctcgtccc ccaaaaataa atgtttttcc atgtgtatct gttttcttaa
     8581 tattgactat tcacactatt tagccgccaa aggtaatgaa aaatgttcaa tttagaatga
     8641 gagacttatg atttatacta gatccattac cgtatccggc gcctattcaa ctccgcccga
     8701 taccggttgg cattgcggtt atgctccgcc aacgtcacgg cgaaattatg ccgtcccgag
     8761 aaatcctcct tagcgcacat gtataagtat ttatgtttcg tatgattcaa tacgctattc
     8821 aagcccttga tagtaggaat ccgtagagga ccaggaggca ggcccgcata tttataggta
     8881 ttatagggag aatctatttc caaatgctca aataagatac gttgcaaaga aaaatccccc
     8941 accgcgaact ttacggtagg gtctgcctgt aaaggaatac cagcatgaag gcggttgata
     9001 taaaggcccg ccacgattgg atattcgtcc gatgccgccg tctcctcttc tacgatagaa
     9061 gccaagatag atacctcgac tggagtaagc ccgatctcct ctgccttttt caatcgttcc
     9121 ggtgtccaga aagcgtcata ttcacgcttc atgcgacgta taaatttatc cgcggatata
     9181 ttccaataaa tctcataggt attaggaatg aagagggcat cgatcgtttc cggggtaaaa
     9241 cctaaagagt cgcaatacac agaatcattc aatagacgca ggagattttc cttcccgaac
     9301 atcaattgat cacttatacg ttccgccaaa tcttccttga aacggatatt attaaaagta
     9361 acccgggccg ctacttgatg tcctctccgc aaatcattca ataaggttaa attactcatg
     9421 ccgggcttca cggcgtatcg accggtacgc atggacgcag gatacttcaa caatccactc
     9481 aattgcttaa agctaccgat acggagacag ttcgccgaat ccctcaactg ccggcaaaga
     9541 tcatcaaaat cctttttatc atctatatag acatagaccg tcttatccgg cttaaaattc
     9601 ggagcccaag ccaaacggta cacccaaaag cctccaccgc ctatcaaaac aacgagaatc
     9661 gctatcaagg cgataattat cgggcgcctc gataaaattt gtttgttcaa atccatgaat
     9721 aatctattga atatcagaat aaggcacaaa agtagtatct tttttcgaaa aaaatgatgt
     9781 gcaaagcctt gtttatttaa aattatagtt ctacctttgc atcgcaattc taaggaagaa
     9841 gcacagaaca cacaaggaag tgtgggtgag tggctgaaac caccagtttg ctaaactgac
     9901 gtactcgtaa gggtaccggg ggttcgaatc cccccgcttc cgcaaagagc caactaataa
     9961 atttattagt tggttttttt gtttttaagc caaccgaatt aaagtgtttc atatatttgt
    10021 catatttgaa cttatcgtaa gtcgatctgt tattaaaagg agataattaa atatatacat
    10081 tatgacaatt gcttttatcc gaacatataa taataagcaa aactccgagg tccaagaagc
    10141 tgtgatccgg gaatttgccg aatctcagaa gatagagatc gggaagtggg ctaaagaggt
    10201 gggaaatagt cctcgtgcga accgcagact ggaaagtatt gtcaaatctt taagtcccgg
    10261 ggatgagata cttgtgtccg atatatcccg tgtgagccgt aagatgatcg agatcatcca
    10321 tatcattttg ctttgtatag agcgaaaggt aacgcttcgt agcgtaagcg acggatatgt
    10381 gttcgaggat aatatcgaca gtaagacttt ggcctttacc ttcggtctgg tctccgagat
    10441 cgagcgaaag ctggtctcta tccgtacgaa ggaagccctt gccttgatca gaagtaaagg
    10501 tgtggtgctg ggccgtccga aaggtagtca acaaatggga cgcttggagc cttataagga
    10561 acaaatcgag aaagacttga aagatccgag cttgacttac gcccagatag cggagaaata
    10621 caatgtatcg ctaagtagct tcaaacgctt tctgaaagag tatcttcccg ataagaaaaa
    10681 gaagaagaag aaataatgat tcaatgtgcc aatatgccaa tgaaatacca gaagtggata
    10741 attcagatat tagcatattc gcatattggc acattgaatc attattattt ctctatacgg
    10801 atacgggcgt ctacagcgaa caagcctcta tccgtagcca ccaacggatt tatatccatt
    10861 tcctttatct cgctggcaaa acgcaataag gtagagaggc gaacgataat gtccgcatat
    10921 tgttgctcgt cgatgccctt ttgcccacgc gtacctttaa tgatcggata ccctctcaaa
    10981 gaacgaatca ttgaataagt ctcatcatat gataacggtg ccaaaccata agacacatcc
    11041 ttcaatacct ccacgaagat tccacccaac ccgcaaagta ccacatggcc gaaacgatcc
    11101 tcatatttag ctcccaagaa taattcctgt cctttcaaca tcggttgtac catgatgccc
    11161 gtaacacccg gcagacgcat catacgttca tactcgaaca ataaatgctc ttctccacgg
    11221 atattcaagg ccacaccacc gatatcgctc ttatgcacag gccccacaac cttggctacc
    11281 accggatatt tcaccttctt ggcaaaagcc agcaacgcat ccctatcatc cgaagcatat
    11341 tcctccacta acgggatatt agcggcacgc aacaatgtac gcacttcctc cggatttaaa
    11401 taaccgctac ccggcaaccg gtctatgata cgacgaactt ccggtacatc cacgccatat
    11461 agctggatat ccgtgctcat cggtttcggc gtattgatca cccgtgaaag ggcagtaccc
    11521 aatgtcacct cgtccgagaa gttcacatgg cctttcttga caaagctctt cacctccggt
    11581 ccggccgtta cgatagacgg taatatcggg aagatcggct tcttgcactc ttccatcttt
    11641 ttatgaagta cctcgtaggt atcataaagt tttaccaaac cgggactacc gaagatgacc
    11701 atcatcaaat ccacattatc gaaacgattc tcacagaaat cgatggctgt agccagatgt
    11761 tccggtgtcc ccgtaccgat aatatcaatc ggattaccga cagcggcacc cggatacagt
    11821 ttggatttca actcatcagc gatagggcct tccaaactag gaacattcaa acgccccttg
    11881 gataaagcgt ccgccagcat taccgcaggc cctccggcat gtgtcacgat cgcacaattc
    11941 ttccctttca cgtctttcaa ggtaaagata ctcgccacgg tagtcaattc ctcacggcta
    12001 aaacaacgca cgatacccgc cttacggaac aaagcctcca cggcagagtc cgaactagcg
    12061 atagcgcccg tatgcgaaga ggcagctcgc tttcccgact ccgtacttcc cgccttgata
    12121 gcggcgatct tgcatccctt acgtatcaag gaagacgcat gatacaacaa tttatccggt
    12181 tgcttgattt gctcgatata caacatcttg atcttggaat ccaataccgg atcaaagttc
    12241 cgatccatat attcaaggat atcctctact ccattctgct tggagttccc aaccgaccaa
    12301 acagaagaga aacgcagccc ttttgtcagc gccgactcga taatgaacaa ggccgtaccg
    12361 ccggagctag agatgaaatc cacgccatcg ggatggaatt ccggtatcgg ttgcgtaaac
    12421 acgccatgat aattcatatt catcaacccg atacagttcg ggccgatcaa ggaggctccc
    12481 gcctcattca cgacatccag catctgttgt tccaagatac cgccctcgtg tgtctcctcg
    12541 ccgaagccgg ccgagatcac gataaaagct tttaccccct tttgccgggc cagcacttcc
    12601 atcacctcgg ggcacgattt actcggaatc gagatgatcg ccaactccgt ccccgggata
    12661 tcatgtacag aaggataaga cttgacgcct tgcacatctg tctccttggc gtttaccaca
    12721 cataattctc ctttatattt tccatccaac aggtttcgca cgatacgacc gcccggttta
    12781 tgtacgttgt tggaacctcc caccactacg atgctttgag gattaatcaa ttctcggtta
    12841 atcataacat tttgattagt tagattcaat gaatgggagc aaatatagtt tttttctcca
    12901 tttattcatt aaaacccggg gtatttattt acactttgca ctctctgtct gcaaccagtc
    12961 acaccatgca tccatcccgt ctcctttcgt ggcggatacc tcgaatatct ggagatggtg
    13021 atttaccttc aaggcgtttt cccgaagcac ttccactttt gtattcagat aaggagccag
    13081 atcaatcttg ttgattacgc agatatctgc ctcctgaaag atatgtgggt atttcaacgg
    13141 tttatcatcc ccctccgtcg tactcacgat aacgactttc ttggactctc cgagatcgaa
    13201 catggccgga cagaccagat tgccgacatt ctctataaaa aggatcgctc cctccttcgg
    13261 attcagatgc ttaacggcat gattgaccat gtcggcttcc aaatgacagc cggtaccggt
    13321 atttacctga aacacgggaa tctccaacgc cgctatacgg tcggcatcgt ttgaggtttg
    13381 ttgatcgcct tctatcacat agatcggtcg cttcgctttc aaacggcgga tcgtctcttc
    13441 cagcaaagtt gtcttaccgg atccgggcga actcatcaag ttcaggcaga acaggttctt
    13501 agcctcgaaa tatccccggt ttcgctccgc caataagttg ttacgttgaa gtatatcttg
    13561 ttccagattg attacgatcc cttcatcagg atggtgatga tgttcatggc catgagaatg
    13621 ctcatgcgca tgatcgtgat ggtgatgatg ctctccgcat ccgcaagttc cgcacatagt
    13681 atttaagttt ttatttcatt aatatatcat tcctttttaa taacaatcga cttcacccga
    13741 agttccttcc ctttaaggat tttaactaaa taggagccac aatggggaca aggggaaaac
    13801 aaggcgttca ttgggaaaat ggtctcacag tcgctacact gtccttcccc ctcaatataa
    13861 tgacggataa tccgggcctt ttccagcttg ctacctttta tggcgctatc caatgcgaac
    13921 gctaaggttt ggatctctac gccggacaaa tgtcctatct ctaactccaa ctcttcgacc
    13981 accgaggctc cccggttatc cgcttgttcc tcgaccagct ccacgatgct acgggctata
    14041 gacaactcat gcatatctga tctcttttaa aagggagtca ccgaggcgat cgttaattgc
    14101 cccacggcta tccccccatc gttacaaggt atacgagacg gaatatagac ggggacccca
    14161 gccatgatga actgtctcct catcgactcc gtcaataatt tattctggaa acatcctccc
    14221 gagataacca cttgtgtcgc tttcgtccgt ttaatcaaca agcgggcttt ctgcacaaac
    14281 aaggaagcca atgtcgtatg gaaacgggcg gatatcaagc tcaccgggac ctcgttcgtc
    14341 ttatcatgca ataatgcctc aaacaaagaa taaaaagaga tttcctctcc ctccgccgag
    14401 actggatacg cataagcgtt cctctctccc atcgccgcct gctccaataa gaccggagcc
    14461 tccgcttggt ggctggagac atcgcaaatt cccaataaag aagctaccgc atcaaacagc
    14521 cggccagcgc tggatgtata gggtgtattc acacctttct ccatcattcg ttcaagcata
    14581 gcgatccttt ccgtgcctat gcgttccacg aaatcggccg gataaggaat acccgacggt
    14641 tcgtccttga aataatgcca caaataggcg acaaccattc gccatggctc ctcagccgcc
    14701 ttgtcgcctc ccggtaacgg gacatactca aaatgggaaa ggcgacggta tttcgctcgg
    14761 tcacaaaaga agaactcgcc tccccaaacc ttaccatcat cacccagacc tgtcccatcc
    14821 atcacgatag cgagaaccgg ctcattcaat ccatgctcca acatacaagc agcggcatga
    14881 gcatgatgat gttgtacctt taataaaggt aaggaaagag atttcgagat acgttccgcc
    14941 tcttggctgg aaagataatc cggatgcagg tcacaaacca atcgctgggg attgaaacga
    15001 aacaaatgac gaaactgctc catagattcc gtatagaacc ggaaagtctc ccagttcttt
    15061 aagtcgccaa tatattgact ttgcaggatc gtctctcctt tccccaaagc gaacgtgttc
    15121 actttctccg caccgaaagc catgatcccc tccacatttg tatccgtgaa aaagggttcc
    15181 ggcacatagc cccgggaacg acggatcaag caaggttgtc ctccgcagac ctgcaataca
    15241 gaatcatcta cccggttatg gatcgggcga ttatgatgca agaggatcgc tacctttccc
    15301 gctaattgcg cctccgcatc ctccggggtg atcgctatcg gcaaatcgct tagattcccg
    15361 ctggtcatta ccaacgcagg tatccctgta cgagcaaacc aatcgtaatg aatcggcata
    15421 taagacaaca tacatcctag cgtatgcatg cccggattga ttccggaagc taaccggctc
    15481 cgttgcctca gcagtacgat cggacggcgc caagaaacta agcatcgctc ctccatcggc
    15541 tccgttactg tatagacttg cagatgttcc agatcacgga acataacagc gaatggtttg
    15601 gtatcccgct gctttatctc tcgcagacgg gcaaccgctc tctcgttcga ggcatcacaa
    15661 atcaaatgat agcctccgat tcctttagcc gcaataacct ctccaccaag caataagcga
    15721 gaggtaagtt tcaataaggt ctcataatag atataagtct cctcgttata agtcgcgtaa
    15781 taagtcgggc cacaatgatt gcaagcgacc ggttgggcat ggaaacggcg atcgataaca
    15841 ttcgtatatt ctttctcaca atcgggacac ataaggaaac cgcccatcgt tgtctgcgaa
    15901 cggtcgtaag gaaggtcccg gataatagag aagcgagggc cacaatgcgt acaattaata
    15961 aaaggatatc cgattcgatg gggttgagta gtccggtctc gcatacaatc cgcacaaaca
    16021 gcgatatccg gggagacctg cgtgacctca tccgattctg aatggctagg cgtaatcgta
    16081 aaatcgtcaa aatcatcttc atccatttcc gtagatgtat aggagatccg atggatataa
    16141 gcgacacgag gatgctcggt ccgtatacga cttatcagca aatcccgatc atccggagta
    16201 gcggcaacca agatacgtac tccattattc atattctcca cacaaccttt catccccaga
    16261 tctttagcga tccggtagat aaaagggcga aaaccaaccc cttgaaccaa gccttgaata
    16321 atcaacgcat atactttatt cttcgccata gcacaaatat aggaagaatt cgtgagattc
    16381 aggcagattt tggtggaata aagtaagtga ttggaggcta aaggaattcg gtgttgaatg
    16441 acaatgttct tccttttact gaaaaagcgg gatatcgaga ggttatgagg taattttgct
    16501 acctatccgt tgcccttttt tagtgtcaat ccggtggtga aaacg
//
