LOCUS       c00054_gnlPro..         9479 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|LJBHKMFB_54.
ACCESSION   c00054_gnlPro..
VERSION     c00054_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-07 21:22:51
            Original ID  :: gnl|Prokka|LJBHKMFB_54
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 9479
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..9479
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[1:4486]"
                     /cutoff="10000"
                     /detection_rule="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /neighbourhood="10000"
                     /product="succinate2propionate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      2..4486
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /neighbourhood="10000"
                     /product="succinate2propionate"
                     /protocluster_number="1"
     cand_cluster    1..9479
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /kind="single"
                     /product="succinate2propionate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..9479
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="succinate2propionate"
                     /region_number="1"
                     /rules="(minimum(4, [AcetylCoA_hyd_C, AcetylCoA_hydro,
                     B12-binding, Biotin_lipoyl, Glyoxalase_4, HMGL-like,
                     MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma, PYC_OADA]) and
                     minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /tool="gutsmash"
     CDS             complement(2..1111)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: OAD_beta"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg54_1"
                     /sec_met_domain="OAD_beta (E-value: 2.6e-147, bitscore:
                     479.7, seeds: 229, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQESFLQFLGENIQIFLSYTGFANATPGHIVMLLVGLLFIFLAIK
                     YEFEPMLLIPIGFGILIGNIPFKDAGLQLGIYEEGSVLNILYQGVKQGWYPPLIFLGIG
                     AMTDFSALISNPKLMLVGAAAQFGIFGAYIIALQMGFDPSQAGAIGIIGGADGPTAIFL
                     SSKLAPNLMGAIAVSAYSYMALVPIIQPPFMRLLTTKKERVIRMKPPRAVSQTEKIVFP
                     IVGLLLTAFLVPSGLPLLGMLFFGNLIKESGVTRRLAETARGPLIDVITILLGITVGAS
                     TQATQFLTLNSIKIFGLGALSFVIATCAGVLFVKFFNLFLKEGNKINPLIGNSGVSAVP
                     DAARISQNVGLEYDPSNYLLMHAMGPNVAG"
     CDS             complement(1116..1547)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: Biotin_lipoyl"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1024:Biotin-requiring enzyme (Score: 63.7; E-value:
                     3.5e-20)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg54_2"
                     /sec_met_domain="Biotin_lipoyl (E-value: 5.7e-21, bitscore:
                     63.7, seeds: 40, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKSFKYTINGNTYKVHINSVVDDVAEVEVNGTPYNVKMEKPAKKQ
                     MVTLKRPAQAPTNASGEPVITRQAAPSVAGAVKSPLPGVILSVDCKVGDTVKRGQKILV
                     LEAMKMENNINADRDGKIVEIKVNKGDSVLEGADLVVIG"
     CDS             complement(1571..2464)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: OAD_gamma"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg54_3"
                     /sec_met_domain="OAD_gamma (E-value: 1.3e-13, bitscore:
                     40.9, seeds: 234, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MINKKIGVLLLLMVLFSMGAKAQLTTSVKLNEVLVVNEDNFVDDY
                     GKRHPWFELFNNSAGTVDLRGCFLTNDKSNPRKYMIPKGDVLTKVPPRQHLLFWADDQP
                     TKGTFHVNFTFDPNKDNYLALYDSDGTTLIDEVTIPAGQKADVSYGLDLDGVGNWSILD
                     KVTPSTNNLTLDSNAKLENFQRNDPWGIGMTITAMAVVFLGLIILYLVFKQIGNAAIKA
                     SKRNAQKAAGTGAAVSANIGQESGEIFAAIATALYEMSDDNHDIENTVLTIHKVQRSYS
                     PWSSKLYSLRQTPNKK"
     CDS             complement(2486..4039)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: CT_Btheta"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg54_4"
                     /sec_met_domain="CT_Btheta (E-value: 8.4e-293, bitscore:
                     960.5, seeds: 72, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSNQLEKVKELIALREQARLGGGEKRIESQHKKGKYTARERIAML
                     LDEGSFEEFDMFVQHRCTNFGIEKTKYLGDGIVTGYGTIDGRLVYIFAQDFTVFGGALS
                     EALAMKICKVMDQAMKMGAPVIGLNDSGGARIQEGVNALAGYAEIFQRNILASGVVPQI
                     SGIFGPCAGGAVYSPALTDFNIMTRGTSYMFLTGPKVVKTVTGEDVTQEQLGGASVHTT
                     KSGVAHFAVDTEEDGLQLIRKLLSFLPQNNLEETPLVECKDPIDRLDDVLNDIIPDNAN
                     QSYDMYEVIGTIVDNNEFLEVHADYAKNIIVGFARFNGQSVGIVANQPKVMAGCLDSNA
                     SRKAGRFVRFCDAFNIPLVTLVDVPGFLPGTGQEYNGVILHGAKLLYAYGEATVPKITV
                     TLRKSYGGAYCVMSSKHLRGDMNYAWPTAEIAVMGPSGAVEVIFAKEVAAAEDPKACAA
                     EKEAEYKKAFANPYNAAQYGYIDDVIEPRNTRFRIIRALQQLQTKKLSNPAKKHDNLPL
                     "
     CDS             complement(4076..4486)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: Glyoxalase_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg54_5"
                     /sec_met_domain="Glyoxalase_4 (E-value: 2.2e-27, bitscore:
                     85.0, seeds: 51, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MELTHIEHLGIAVKSIEACLPYYEGVLGLKCYNIEVVADQKVKTA
                     FFKVGQTKIELLEPTSEDSTIAKFIEKKGEGIHHIAFAVPDVQAALNEAEEKGVKLIDK
                     APRGGAEGLNIAFLHPKSTCSVLTELCMPGNK"
     CDS             complement(4615..7026)
                     /locus_tag="ctg54_6"
                     /transl_table=11
                     /translation="MKIRAIAALLFILISVSAFGEGRIKITGYVRDADGNPLELVNVRV
                     KNTLIGSMTNEKGYYSFSISPGDSISIIYSCLGYNKAERIIPSAQADMRLNVQMNNTSF
                     DLGEVSVTAIRKQTTTMESLNADKIKLLPDPSGGSIESLVVTFAGVSSNNELSSQYSVR
                     GGSYDENIVYVNGIEVFRPLLIRSGQQEGLSFINPDLTEAVNFAAGGFEARYGDKMSSV
                     LDITYKKPKIFEGSASASLLGANAYVGSSIGKFTQVTGFRFKSGRSILGTMDTDAEYNP
                     KFIDLQTYITYQLAPKWEINFLGNLANNNYKFTPYSRETSFGTAEHPKNFKVYFDGRER
                     DRFQTLFGALTLKHNPNENTELGLQASAFKSKEEEGYDIAGEYWLSENGAENPDDDASA
                     AMSVGRYHEHARNRLNSTVMNVGHYGMARLLNNTLKWGATVQMEKINDKISEWEKRDSS
                     GYSLPQTGNNVSVYSNLFSDNQIESTRFSAYAQDAFKFRTKQGLFTLVAGVRGSYWTYN
                     KEFLFSPRASLGFIPNFDQDLTLRFATGLYYQSPFYKELRRVDKDKNGNNITVLNKDLK
                     SQRSIHFILGGDYTFRAVDRNFKVTAEMYYKKLDNLNPYTVDNVKIRYYGENCAKGYAM
                     GLDVKFFGEFVPGTDSWISFSLMKAQQTIRETTTVPMANSQGYNISLFFQDYFPGYKRV
                     KLNLKGVLSGGLPQTIPGKGYEAGYFRTPAYKRVDIGLSYQLAGGTDAIMDRSFFRHLK
                     NIWLGLDVFNILDIKNVSSYYWITDVYNVQYAVPNYLTGRQLNVRLIVDF"
     CDS             7148..7708
                     /locus_tag="ctg54_7"
                     /transl_table=11
                     /translation="MESFATLIQNRRSTRKFTEQLLSPEQVELILKAALMAPASKRSNP
                     WQFVVVEDKEMLKKLAGCKKNGSAFLEGCALAVVVLANVMESDVWIEDASVASIYMQLQ
                     AEDLGLGSCWCQIRNRVTEDEADSNNYVRSLLDIPYQLDVLSIIGIGYKDQVRKPFDES
                     HLQWEKIHIGKFSLPEENKEAEE"
     CDS             7705..8472
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) F420_oxidored"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg54_8"
                     /sec_met_domain="F420_oxidored (E-value: 7.3e-10, bitscore:
                     28.9, seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRVVFVGAGNLATRLSLEMRKSGMSIGQVYSHTSEHAKILADELG
                     CGWTVVPEDIVEDADLYVFSLKDAVLQDVIARVKPNNGLWVHTAGSMPISVFEGLTARY
                     GVVYPLQTFSKSREVDFKKIPFFLEANSSEDEKVLGEVARALSSDVRFLSSEKRKNLHL
                     AAVFACNFTNHMYALAEKILEEQQIPGEVLLPLIDETAAKVHVMSPARAQTGPAIRYDE
                     NVINKHMAMLKDPDMRNLYELISRSIHKEARHE"
     CDS             8465..8986
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HAD_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg54_9"
                     /sec_met_domain="HAD_2 (E-value: 5.4e-09, bitscore: 25.8,
                     seeds: 51, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSSINYDLRKIKAFVFDVDGVLSCDVIPLHPNGDPMRTVNIKDGY
                     ALQLAVKKGYEVAIITGGYTEAVQIRFSRLGIQHIYMRSAVKVHDFKDFMEKTGLSPEQ
                     IMYAGDDIPDYEVMTQVGLPVAPADAAPEIKEIAKYISSRRGGEGVARDVIEQTMRAQG
                     HWFGEEAFGW"
     CDS             9024..9479
                     /locus_tag="ctg54_10"
                     /transl_table=11
                     /translation="MLENLKKYKIVLASNSPRRRNLLSGLDIDFEVRVIPDIDESYPDS
                     IDSMEIPLYIARSKAEAYKSTMADDELLITADTIVWTFDGVMGKPANREEAYAMLHALS
                     DHVHQVITGVCIMTKDKNVGFSVESAVCFAKLGDCLLYKSDAADEEDS"
ORIGIN
        1 cacctgctac gttcggaccc atagcgtgca tcaataagta gttacttgga tcgtattcca
       61 aacctacgtt ctgggaaata cgggcagcgt caggtacggc ggatacaccg gagttaccga
      121 tcaacggatt gatcttgttg ccttctttca ggaacaggtt aaagaactta acgaacaata
      181 caccggcaca agtagcgata acgaatgaca acgcacccaa accgaaaatc ttgatagagt
      241 tcaatgttaa gaactgggta gcttgtgtag aagcacctac cgtgatgcct aataagatcg
      301 tgataacatc gatcagcggg ccgcgggctg tctctgccaa acggcgagta acaccacttt
      361 ccttgatcaa gttaccgaag aacaacattc ctaacaatgg caaaccagac ggtaccaaga
      421 aggctgttaa taacaagcca acgatcggga aaacgatttt ctccgtctgt gaaacggctc
      481 ttggaggttt catacgtatc acacgttctt tcttcgttgt aagcaatctc ataaacggtg
      541 gctggataat aggaaccaat gccatatatg agtatgcgga tacagcgata gcacccatca
      601 agttaggagc taacttggat gacaagaaga ttgcggttgg accatcagct cctccgataa
      661 taccgatagc accggcttgg ctcgggtcaa atcccatttg caatgcaatg atataagctc
      721 cgaaaatacc aaattgggcg gcagctccga ctagcattaa cttaggattg gatatcaaag
      781 cggagaagtc tgtcatggca ccgataccga ggaatatcaa ggggggatac caaccttgtt
      841 tcactccttg gtataaaatg ttcaatacag aaccctcttc gtatatacct aattgtaatc
      901 cggcatcctt gaaagggata tttccgatca agataccgaa accaataggg atcagaagca
      961 ttggctcgaa ttcatattta atcgctagga atatgaacag caaacctacc aatagcatca
     1021 cgatatgccc tggagtcgcg ttcgcaaatc ctgtatagga gagaaatatt tggatatttt
     1081 ctcctaggaa ttgtaagaaa ctttcttgca tatcattaac cgattacaac gagatctgca
     1141 ccttccaata cagagtcgcc tttgtttact ttaatttcta caattttacc gtcacgatcg
     1201 gcattgatgt tgttttccat cttcatggct tccaatacca agatcttttg gcctctctta
     1261 actgtatcgc cgactttaca gtctacactt aaaattacac ctggcagcgg agatttaaca
     1321 gcgccggcta cacttggagc tgcttgacgg gtgataacag gttcaccgct ggcattggtc
     1381 ggagcttgag ccggacgttt caatgtaacc atttgttttt tcgcaggttt ctccattttt
     1441 acgttataag gggttccgtt tacctctacc tctgccacat catctacaac tgagttgata
     1501 tgtactttat atgtgttacc gttaatggta tatttaaaac ttttcattcg tcaattggat
     1561 tttaggatga ttacttttta tttggagtct gacgcagaga ataaagctta gaactccatg
     1621 gtgaatagct gcgttgaacc ttgtggatag tcaataccgt gttctcgata tcgtggttgt
     1681 catcgctcat ctcataaaga gcggtagcga tagcggcaaa aatttcacct gattcttgac
     1741 cgatattggc tgatacggca gcacctgttc ctgcggcttt ttgagcgtta cgcttgctag
     1801 ctttgatcgc tgcgttaccg atctgcttga atactagata caaaatgatt aagccaagga
     1861 atacgactgc catggctgtt atggtcatac caatacccca tgggtcgttc cgttggaagt
     1921 tctcaagttt cgcattcgaa tctaacgtca gattattggt gctaggagtc actttgtcaa
     1981 ggatactcca attacctact ccatcaagat ccagaccgta actaacatct gctttttgcc
     2041 cggcagggat tgtcacctcg tcgatcaaag ttgtaccatc tgaatcatat aaggctagat
     2101 aattatcttt gtttggatcg aatgtgaagt ttacatgaaa tgtccctttt gttggctgat
     2161 catctgccca aaaaagaaga tgctggcggg gaggaacttt ggtaagtaca tctcccttcg
     2221 ggatcatata ttttctggga ttacttttat cgttcgttaa gaagcatcct cgtaaatcca
     2281 ccgtacctgc tgagttatta aacaactcaa accatggatg gcgttttcca tagtcatcaa
     2341 caaagttatc ttcattgaca actagcactt catttaattt aacggaggta gtcaactgtg
     2401 ccttggctcc catactgaag agaaccatta acagtagcaa tacccctatt ttcttattta
     2461 tcatattcat ctcctgtttt acggattata gaggcaggtt atcatgtttc ttagcaggat
     2521 tgcttaactt cttagtctgc aattgctgca aagcacgaat aatacggaaa cgagtgttac
     2581 gcggttcgat aacatcgtcg atataaccgt attgagctgc gttataagga ttagcgaatg
     2641 ctttcttata ttcagcttct ttctctgctg cgcatgcttt cggatcttca gcggctgcta
     2701 cttccttggc gaagataacc tctacggcac cgctcgggcc cataacggcg atctcggctg
     2761 tcggccatgc gtaattcata tcaccacgta aatgtttaga actcatcacg caataagctc
     2821 caccgtaaga cttacgcaat gtaacggtaa tcttaggaac ggtagcctca ccataagcgt
     2881 aaagcaattt agcgccatga aggattacac cgttgtattc ctgacctgta cccggaagga
     2941 atcccggaac gtcaaccaat gttaccaaag gaatattgaa agcgtcgcag aaacgaacga
     3001 agcgacctgc tttacgagat gcgttgctat ccaagcatcc tgccataacc ttcggctggt
     3061 tagctacgat accgacggat tgtccgttga aacgagcgaa acctacgatg atattcttag
     3121 cgtagtccgc atggacctct aggaactcgt tgttatcgac gatcgtaccg ataacctcat
     3181 acatatcgta agattggttg gcgttatcgg gaatgatatc gttcaataca tcatccagac
     3241 gatcgatcgg gtctttgcac tcaactaacg gcgtttcctc taagttgttc tgaggtaaga
     3301 aactgagcaa tttacgaatc aattgcaaac catcttcttc tgtatcgaca gcgaaatggg
     3361 ctacacccga tttggtagtg tgtacgctgg ctccacccaa ctgctcttgg gttacatcct
     3421 cacctgttac ggtttttacg actttcggac cagtcaagaa catatagctg gtaccacgtg
     3481 tcatgatgtt gaagtctgtc aaagccggag aataaacggc tccaccggcg caagggccga
     3541 agataccgga aatctgggga acaacaccgg aagccaagat gttacgttgg aaaatctctg
     3601 cgtatcctgc caaggcattt actccttctt ggatacgagc tccaccggag tcgttcaaac
     3661 cgataacggg agcgcccatc ttcatggctt gatccattac tttacagatc ttcatagcca
     3721 aagcctcaga caaggctcca ccgaatacgg tgaaatcttg agcgaagata tataccaaac
     3781 gtccgtcgat cgtaccataa cctgttacga taccatcgcc taaatattta gttttctcga
     3841 taccgaagtt tgtacaacgg tgttgaacaa acatgtcgaa ttcctcgaaa ctaccttcgt
     3901 caagcaacat ggcgatacgc tcacgagcgg tatatttgcc ttttttgtgc tgtgattcga
     3961 ttcttttctc tcctccaccc aagcgagctt gctcacgaag tgcgatgagc tcttttactt
     4021 tttcaagctg gttactcatt gtattttgat ttgttgttag aaatgaacgg attaattatt
     4081 tgttgcccgg catgcaaagt tctgtcaata cgctgcaagt tgatttcggg tgaaggaaag
     4141 cgatgttcaa gccttccgca ccaccacggg gagctttatc gattaattta acgccttttt
     4201 cctcagcctc gttcaaagct gcctgtacat caggtaccgc gaatgcgata tggtggatac
     4261 cttcaccttt tttctcgata aatttcgcga tcgtgctatc ttcgctggtc ggctctagta
     4321 attcaatctt agtctgtcct accttgaaaa atgcggtttt tactttttgg tctgctacta
     4381 cttcgatatt gtagcatttt aatccaagaa cgccttcata atagggtaaa caagcctcga
     4441 tactcttcac tgcgatacct aaatgttcga tatgtgtaag ttccatgtca ataataattt
     4501 aaagatttag taaatgtttg tttctattgt gtgcaaatgt acactacttt ttatgaatga
     4561 ggaaataatt ttttgttttt atctcccagt aaatgtgttt aaagatacat tttattaaaa
     4621 atcgacaatc agacgaacgt tcaattgacg tccggtcaga tagtttggaa ctgcgtattg
     4681 gacattatat acatctgtta tccaatagta ggaactaacg tttttgatgt ctaatatgtt
     4741 aaacacatcc agacctagcc aaatgttttt caaatggcgg aagaagcttc tgtccatgat
     4801 agcgtccgtg cctcctgcca attgatagga gagtccgata tctacacgtt tgtaggcggg
     4861 cgtacggaaa tagccggctt cgtatccttt gcccgggatt gtctggggaa gtcctccgga
     4921 tagaactcct ttcagattta gcttgactcg tttatagccc gggaaataat cttggaagaa
     4981 gagtgagatg ttgtagcctt ggctattggc cataggaacg gtcgttgttt cccggatggt
     5041 ttgctgggct ttcatcaagg agaagctgat ccatgagtcg gtacccggta cgaattctcc
     5101 gaagaatttg acatcgagtc ccatggcgta acctttggcg cagttctcgc cgtaatagcg
     5161 gatcttgacg ttatctacgg tgtagggatt cagattgtcc agctttttat agtacatctc
     5221 ggcggtcacc ttgaaattcc ggtctacggc acggaacgta taatctcctc ccaatatgaa
     5281 atggatggag cgttgtgact ttagatcttt gttcaatacc gtgatattat tgccgttctt
     5341 atctttgtct actctacgta attccttgta gaagggcgat tgataataca gtccagtggc
     5401 gaaacggagc gtcaagtctt ggtcgaagtt cgggataaag cccaatgagg cacggggact
     5461 gaaaaggaac tccttattat aagtccaata actacctcta actcctgcga ctaacgtgaa
     5521 cagaccttgc ttggtcctga atttgaacgc gtcttgcgca taagcggaaa agcgtgtgct
     5581 ttctatctga ttatcagaaa agaggttcga atatacactt acgttattac cggtttgggg
     5641 caaagaataa cctgaggaat cccttttttc ccattcactg atcttatcat tgattttctc
     5701 catttgtacc gtggctcccc atttcaacgt attgtttaaa aggcgggcca tcccatagtg
     5761 cccgacattc atgacggtgg agttcaaacg gtttcgtgcg tgctcgtgat aacggcctac
     5821 ggacatggcg gctgacgcgt cgtcatccgg attttccgct ccgttctcgc tcagccaata
     5881 ttctccggcg atatcgtatc cctcttcttc cttgcttttg aaagcggagg cttgaagtcc
     5941 caactctgtg ttctcattgg ggttgtgttt caatgtaagc gcaccgaata aggtttggaa
     6001 acggtctctt tcccttccgt cgaaatagac tttgaagttc ttgggatgct cggctgtacc
     6061 gaaagaggtt tcccggctat aaggggtgaa tttataatta ttgttagcga ggtttcccaa
     6121 gaaattgatt tcccatttag gggccaattg gtacgtgatg taagtttgca gatcgataaa
     6181 tttagggttg tattctgcgt ctgtatccat ggtacccaaa atagaccgac cgcttttaaa
     6241 gcggaaaccc gttacttggg taaatttacc gatagaactg cctacataag cattcgcgcc
     6301 caacaagctc gcagaagctg agccttcgaa tatcttaggc tttttatagg taatatccag
     6361 cacggaactc atcttgtctc cgtaacgagc ctcgaagcca ccggcggcga aattgaccgc
     6421 ctccgtcagg tccggattga taaagctaag gccctcttgt tgtcccgagc gaatcagaag
     6481 cggacggaat acctcgatcc cattcacata aacgatattt tcatcataac tacctccacg
     6541 tacggaatac tgggaactta actcgttatt ggacgagact ccggcaaacg taacgaccaa
     6601 gctctctata ctacctccgg agggatcggg caataacttg attttgtccg catttaggga
     6661 ctccatggtc gtggtctgct tgcggatggc agtaacagat acttccccta aatcaaatga
     6721 ggtattgttc atctgtacgt tcaggcgcat atcggcttgt gccgaaggaa tgatacgttc
     6781 agctttatta tatcccagac aagagtaaat aatggagata gaatcccccg gcgatatgga
     6841 aaaggaataa tatcccttct cgttggtcat ggagccgatc aacgtgttct taacccggac
     6901 attcactaat tccagagggt taccgtcggc gtcacggaca taaccagtga tttttatgcg
     6961 gccttcgcca aaggcactca cggaaataag tataaatagc agcgcggcta tcgcacgaat
     7021 cttcataatc tattgttcaa ttataaaaat actaacgaga aaaaagaacg atacgtatat
     7081 atgggtgcaa aaaattatat ttatatttgc gaatcttaat attaaaagag tacaaagaac
     7141 gaaaaaaatg gagagttttg caacacttat acaaaataga agaagtacac gtaagtttac
     7201 cgaacaacta ctttcacccg agcaggtaga actgatcttg aaagcggcgt tgatggctcc
     7261 ggcctcaaaa cgtagtaatc cttggcagtt cgtggtcgtg gaagataagg aaatgttgaa
     7321 gaaacttgcc gggtgtaaga aaaatggttc tgcttttctg gagggttgtg ccttggccgt
     7381 ggttgtcttg gcgaatgtga tggaaagcga tgtttggatc gaggacgctt cggtcgcttc
     7441 tatttatatg caattgcaag cggaggattt gggattgggc agttgctggt gtcagatccg
     7501 gaaccgggta acagaggatg aggcggattc gaataattat gttcgttcgt tgctggatat
     7561 tccttatcaa ttggatgtct tgtctatcat tggtatcggt tataaggatc aggttcgtaa
     7621 gccttttgat gaatcccatt tacaatggga gaagatacat ataggaaagt tctctcttcc
     7681 ggaagaaaat aaagaggcgg aagaatgaga gtcgtatttg ttggtgccgg aaacttagct
     7741 acccggcttt cgttggaaat gcgtaagtcc ggaatgagta tcgggcaagt gtatagtcac
     7801 acaagtgagc atgctaagat tttagccgat gaattgggat gtgggtggac tgttgtcccg
     7861 gaagatattg tggaagatgc cgacttgtat gttttctctt tgaaagatgc cgtgctccaa
     7921 gatgttatcg cccgtgtaaa accgaataac ggtttgtggg tgcacacggc agggagtatg
     7981 ccaatctctg tatttgaagg tcttacggct agatatgggg tggtttatcc gttacaaacg
     8041 tttagtaaga gtagggaggt ggatttcaag aaaataccgt tttttttaga ggcgaactcg
     8101 tctgaagatg agaaggtgct gggagaggtg gctagggcgc tctccagtga tgtccgtttc
     8161 ctctcctccg agaagcgaaa gaacttacat ttagcggcgg ttttcgcttg taattttacg
     8221 aatcatatgt atgcgctagc tgaaaagatc ttggaagaac agcaaatacc gggagaggtc
     8281 ttgctacctt tgatagacga gacagccgct aaggtacatg taatgtcgcc ggcgcgagcc
     8341 caaacgggac cagctatacg atatgacgag aatgtgataa acaaacatat ggctatgctt
     8401 aaagatccgg atatgcgaaa tctatatgag ctgattagcc gaagtataca taaggaggct
     8461 cgacatgagt agtataaact atgatttgag aaaaataaag gcttttgtct ttgatgtaga
     8521 cggggtgcta tcctgcgatg tgattccgct tcacccgaat ggcgatccga tgcgtactgt
     8581 caatatcaag gatggctatg ccttgcaatt ggccgtgaag aaaggttatg aggtcgctat
     8641 aattacgggt ggatatacgg aagccgtaca gattcgcttt tctcgtttgg gaatacaaca
     8701 tatttatatg cgtagcgctg taaaggtgca tgactttaag gatttcatgg aaaaaacggg
     8761 cttgtctcct gagcaaatca tgtatgcggg tgatgatatt cctgattatg aggtaatgac
     8821 gcaagtcgga ttgccggtgg cacctgcgga tgcggctccg gagatcaagg agatagcgaa
     8881 atatatatcc tcccggcgag gtggcgaagg cgtagctagg gacgtgatcg agcaaacgat
     8941 gcgggctcaa ggacactggt tcggcgagga ggcttttggg tggtaaaatt ttggtgaatg
     9001 tgtaacgctt aatcgaatag gttatgttag agaatttaaa aaagtacaag atcgtcttag
     9061 cctctaattc tccgagacga cggaatttgt tatctggtct ggatatcgac ttcgaggtga
     9121 gggtaattcc ggatattgac gagtcttacc cggattctat tgactccatg gagatccctt
     9181 tatatattgc ccgttcgaaa gcggaggcct ataaatcgac tatggcagat gatgaattgc
     9241 tgatcacggc ggacacgatc gtctggacgt ttgacggggt tatggggaag cctgcgaacc
     9301 gggaggaagc ttatgctatg cttcatgctt tgtcggatca tgtacatcag gtaataaccg
     9361 gcgtttgtat catgacgaag gacaaaaatg taggcttttc cgtcgaatct gcagtttgtt
     9421 tcgcaaaatt gggtgactgt ctcttataca aatctgacgc tgccgacgaa gaggatagt
//
