LOCUS       c00131_gnlPro..        13116 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|NGAEBGIN_131.
ACCESSION   c00131_gnlPro..
VERSION     c00131_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-05 15:46:36
            Original ID  :: gnl|Prokka|NGAEBGIN_131
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 13116
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..13116
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[6740:12726]"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      6741..12726
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
     cand_cluster    1..13116
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /kind="single"
                     /product="TPP_AA_metabolism"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..13116
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="TPP_AA_metabolism"
                     /region_number="1"
                     /rules="(TPP_enzyme_C and not (PFL-like or PFL_6_pcresol or
                     PFL_9_tma or Gly_radical or Gly_430_pcre or Gly_8-9_TMA or
                     PFL_acetate1 or PFL_acetate2 or Gly_radical_scatole or
                     PFL_proline or PFL_toluene) and minimum(2, [ALS_ss_C,
                     AlaDh_PNT_C, Arginase, BKACE, BcrAD_BadFG, Beta_elim_lyase,
                     CPSase_L_D2, Cys_Met_Meta_PP, ELFV_dehydrog, GRDB,
                     Glu_syn_central, Glu_synthase, Gly_reductase, HAAA1, HG2B1,
                     HG2B2, HGD-D, HleuD1, HleuD2, HleuS1, HleuS2,
                     Homoserine_dh, ILVD_EDD, IlvC, Lactoyl-CoA1, Lactoyl-CoA2,
                     Lyase_aromatic, MAAL_C, OKR_DC_1_5_lysine,
                     OKR_DC_1_5_ornithine, OKR_DC_1_7_arginine, OKR_DC_1_C,
                     OTCace, PALP, Proline_reductase, Sacchrp_dh_C, TPL,
                     Thr_dehydrat_C, TnaA, Urocanase]) and not (POR or POR_N or
                     PFOR_II))"
                     /tool="gutsmash"
     CDS             complement(580..684)
                     /locus_tag="ctg131_1"
                     /transl_table=11
                     /translation="MNIMSVNGLWRKQTYFLFVHSRKGKHTFINITDI"
     CDS             complement(1353..2942)
                     /locus_tag="ctg131_2"
                     /transl_table=11
                     /translation="MKRFINISFLSLVFAGMALTGCNDDLTTSSYVKVNDEDVLGNVSQ
                     LEKVLTSAYKQLYFNTDKGDRVYAGLPGFQMYVDASGADVISHTNMGGDQVTAYQYSNS
                     KTQADGNASKIWSMCYNVINRANIILTNVDAAAGDETQKKHIKGQALAMRGIQYFHLIQ
                     NYQQTYAIAKSKRGVILRTSSDDESHKGFSTVEEVYTQIVSDLTTAKTLLADYNPDDMW
                     LINSKICSGILARVYLVMQNWDGAYNEAKIVYDQHSQLMTREQYRSGFDDMISGNYAEV
                     VWAMKYTADNNLGGSTQFNFWYNQDASYGEGYADGPIYSFLDYFVDEQFVKLFEEKEDR
                     YQFWKRTNNANTEINTKWAFDKYKHYGEDGGSVIQSATRPEVCLMRGAEMLLIMAEAAA
                     QKGNSGEALNLLNRLQVARNATPTTNAGGEALLEDIYVERRKELICEGQAGFYDLVRLQ
                     KRLVRIGESTTNPAGHYVWGMQYLNGYNALDPQPIGTLESNDYRFFCQIPQMEILNNDA
                     ISESDQNPWSGQ"
     CDS             complement(2961..6239)
                     /locus_tag="ctg131_3"
                     /transl_table=11
                     /translation="MISVLLGAAGAIAANPTGPETMVVQQGNKVTGLVEDQMGPVAGAS
                     VVVKGTTIGTITDIDGKFTLDNVRRGAVIVISFVGLATQEITWNGQSILNVKLSDATQD
                     LDEVVVVAYGTAKKSTFTGSASVVKAEKLEKIMGSGFAEALQGMSAGVNVVNVQGNPGA
                     DARVEIRGIASMSGKADPLYIVDGMPYDGKLNQINPTDIESMTVLKDAAATSLYGSRAA
                     NGVVMITTKRGKSEKPRINFRGGWGTSDNAVKNPKKADPYQQLENTWYALYYDALLYDG
                     MNMQQAGDYASSQALTKQVKATKDSNGNLIYVTPFRHINENYVLHDGNGNPYMNPNLEY
                     VWDEDDWDVYKAIFSRKLRQDYSVDISGQANGGKTAYFFSGGYLDDQGYGNRQYYKRYS
                     FRTNLSTELFDWWKVAGSLSYSRHRQNLSGGASRAANFTTTLSSPWLRNEDNTGWVVSE
                     KTGERMYSYGKYTNNFFGAHILNNSGDYWDNPNDDSFDNNMGHILSAQVNTEFTLPFNL
                     KFRSALNIDDYWYRTMQYTSAVHGSGQTAPYGISILADGGYASRYNFNKRSTTWNNVLS
                     GEWMIGDHTISGLVGHEWYTWDSHYEQGWGEGIMELGKYELSNTTKNFGVSGGRDKYSL
                     LSFFGKVDYNFLNKYYLSASLREDGSSRFSSDHRWGTFWSTGGSWRISKEGFMEDLKWI
                     DNLSLRGSYGTTGNDKLIVRESNGKAGDEVLYGYQGTYESDDLYLKSGLKPSTYPTPDL
                     KWESNQQWNIGLDFSVFNRLSGTVEYYSRTSHDLLYYKELPLSAQVGSASGYNMNIGDL
                     RNSGIEITLNANILTTKDFRWDIDANMSTLKNEVTYLPTGPYTYSGTACTYKMEEGKSL
                     YEFIAPQYDGVNPETGVPGWLIRDGNGGWKRTEKQEEVTTDDFVYCGSAIPKVFGAITN
                     NFQFKGIDLSFMFYYSYGSKISDYTYKERIMNRPGVGVIQELVEDRWRQPGDADVLIPR
                     WSYNQYGATVKYADNFVFDNHYWRLRNLTLGYTLPKSLTRKALVENLRVYVTGNNLLTF
                     GPAKKRYTDPETGIMGNSYNGNAETDNGIQGSRRLYMVGIQITL"
     CDS             complement(6741..7787)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: IlvC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) IlvN"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg131_4"
                     /sec_met_domain="IlvN (E-value: 9.8e-49, bitscore: 154.2,
                     seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="IlvC (E-value: 2.2e-44, bitscore: 140.3,
                     seeds: 295, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAVMNFGGVDENVVTREEFPLEKAREVLKDETIAVIGYGVQGPGQ
                     SLNLRDNGFNVIVGQRKGGKTWEKAVADGWVPGETLFDIEEACEKATIIQYLLSDAAQI
                     EVWPRIKKYLTPGKALYFSHGFGITYKERTNIIPPADVDVILVAPKGSGTSLRRMFLQG
                     RGLNSSYAIFQDATGKAWDRVIALGIGVGSGYLFETTFKKEVYSDLTGERGTLMGAIQG
                     LLLAQYETLRENGHEPSEAFNETVEELTQSLMPLFAENGMDWMYANCSTTAQRGALDWM
                     GPFHDATKPVFQKLYSEVACGNEAQRSIDTNSKPDYREGLEKELAALRESEMWRAGAVV
                     RKLRPENN"
     CDS             complement(7829..8560)
                     /locus_tag="ctg131_5"
                     /transl_table=11
                     /translation="MEKNKVGEFHFVTESYLTDFRGRITIPMIGTYLLHAASCHAADRG
                     FGYNDMTERHTAWVLSRLAIEMTSYPAMSESVTLYTWVDEVGKLFTSRCFELVNGEGKT
                     FGFARSIWAAIDMETRRPTLLDVEGLSAYITDRPCPIEKPGKIAPVENNTSGEPYRVKY
                     SDLDVNGHLNSIKYMEHLLDLFDISLFREKEISRFEIAYQSEGKYGMELTLHNQEVSLD
                     KYNMAICNDGKAISRAAVTWI"
     CDS             complement(8597..9151)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ALS_ss_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg131_6"
                     /sec_met_domain="ALS_ss_C (E-value: 9e-19, bitscore: 56.7,
                     seeds: 685, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNTKQLYTVIIFSENTVGLLNQITVIFTRRQLNIETLSVSPSAIK
                     GIHKFTITTFADEDTIDKVVKQIDKRVDILKAYYNTDEDLVYQEIALYKLSTELFIKMG
                     TVEDLIRKYNARILEMNEDCVVLEKSGHYDETQALFKELSETIGVLQFIRSGRVAITKS
                     KVERLSDMLSAMEKKLQEKHV"
     CDS             complement(9164..10864)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg131_7"
                     /sec_met_domain="TPP_enzyme_C (E-value: 2.7e-51, bitscore:
                     162.5, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDKQKITGSEALLKALIAEGVDTIFGYPGGQAIPIYDSLYDYRDQ
                     LKHILVRHEQGATHAAQGYARVSGKVGVTVVTSGPGATNTITGIADALMDSTPMVVIAG
                     QVPSPLLGTDAFQEVDVIGITQPITKWAYQIRRPEEIAWAVSRAFYIASTGRPGPVVLD
                     LAKDAQVGLVDYEYQKVDYVRSYQPEPDIREERIEAAASLINNAKKPFCLVGQGVILGG
                     AEEELKEFLLKNDIPAGSTVLGLSALPSDFPLNKGMLGMHGNVGPNRKTNECDVLIAIG
                     MRFDDRVTGDLKTYAKQAKIIHLDIDNSEIGKNVPVDVKVLGNAKHTIPMITALLEERK
                     RPEWNAEFEPDEKEEYNKVIEKELYPTEGQLKMGEVVRKVSEATDNDAILVTDVGQNQM
                     MGVRYFKYKQTRSVVTSGGLGTMGFGLPAAIGAKLGAPDRTVCFFTGDGGIQMTIQELG
                     TIMQENLNVKIIVLNNNFLGMVRQWQELFFNERYSNTIMKNPDFVAIAKAFGIASRAVD
                     KREDLDEAIAEMLNHDGAYMLVANVETCGMVYPMVPAGGSVTNMILGDK"
     CDS             complement(10891..12726)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ILVD_EDD"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg131_8"
                     /sec_met_domain="ILVD_EDD (E-value: 2.1e-218, bitscore:
                     715.1, seeds: 918, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MMKNPLRSSYSTEGRRMAGARALWRANGMKEEQFGKPIIAIVNSF
                     TQFVPGHVHLHEIGQQVKAEIEKLGCFAAEFNTIAIDDGIAMGHDGMLYSLPSRDIIAD
                     SVEYMVNAHKADAMVCISNCDKITPGMLMASMRLNIPTIFVSGGPMEAGNLDGRALDLI
                     DAMIEAADDSISDEQVEKVERSACPTCGCCSGMFTANSMNCLNEAIGLALPGNGTVVAT
                     HANRTRLFKKAAKMIVDNAFKYYRDGDDSVLPRSIATRQAFLNAMSLDIAMGGSTNTVL
                     HLLAVAHEAEVDFTMKDIDMLSRKTPVICKVAPSCSYHVEDVNRAGGIIGIMNELVKAG
                     LVDGSVKRADGLTLNEAIDQYCITSVNVTEEAINIYKSAPAHRFNLVLGSQESYYKELD
                     TDRATGCIRDVEHAYVKDGGLAVLYGNIAQDGCVVKTAGVDESIFRFAGPAKVFDSQDA
                     ACEGILKDQVVSGDVVVITYEGPKGGPGMQEMLYPTSYIKSKHLGKECALITDGRFSGG
                     TSGLSIGHISPEAAAGGAIGLVKDGDIIEINIPERTIHVKVTDEELAKRREAEEARGTK
                     AFTPPFRQRTVSKALKAYAKMVASADKGGVRIVED"
ORIGIN
        1 gagcacggga acgggatagt tcaaatattt ctatattgaa acatcctttt gctgcggttg
       61 ccttgtttac tattgatgat ttactttttg ggatataaaa gccaagtcct atccggagaa
      121 catactattg gatacaaagc gtcaggagag ttcctggaag ttaaaggatt gtcaaaatga
      181 tattttatgt atgtgctgaa ggaattgtac gggcaaaggg aaatgtcgat ctgtttttat
      241 agaaatctcg ccgacttacc tttgttcgct ttgacctgat tgttgcaata ttcatatcac
      301 aaaaaatgta tattatctat gattgttacc catataccac atctattcat aatttattaa
      361 catattgcta ttttacacac acatcaaaaa gcggttgctc tggaaataaa aactgtctaa
      421 aaacatatga ttttcttttt taaaagcact aattgaggtg tttttcttct ctaaacgaat
      481 aaaaactcca ctacaataga aatttatctc agtttaaacg aaattgaaat ctgtttaaac
      541 taaaattttc ttcggtttaa acgagataaa aagtcgatat cagatatctg ttatgttaat
      601 aaatgtatgc ttcccttttc tagaatgaac aaataaaaaa taagtctgtt tcctccaaag
      661 gccatttaca ctcataatat tcatatatca ttcattttta tatcattttg attttgccgt
      721 ctgtttggtt acaggaagtg aagtttccat acgacactga tttgcatcaa ccgtttcact
      781 gatatcatgt ccactattat cggttgaaag agaaactatt tttcgcaatg acatacgttt
      841 actggtaatt ctggatcagg tgaaaatact ggattccacg catcgccagc gcctgacctt
      901 tgatgtgttt tttctgtggt acaaatatta tcaggcaact ctttccgata tttattatga
      961 gagataaacc ggatttattt tctactaacc ctttcgacat acgaaaaaag aagtaatctg
     1021 gagccggaag taatcgaaaa gattgccaaa gcattagata tacccgaaga agcaattacg
     1081 gaactaggcg aagccacttc cattaatatc ttttccggca cctggcaaga taatgctaat
     1141 tgccagaatt ataatcctac atttaacccc ttagaaaaag tcgttgaatt atacgaacgt
     1201 ttattgaaag cggagcagga gaaggtggcc atgttacagg aagtgctaaa ggacaaaaag
     1261 taaaacagtg aacatcaaat gttacaaata aaagagaggg aggcatgtaa taaacacctc
     1321 cctctctttt atttatttac aacagatgaa acttactgcc cgctccacgg attctgatct
     1381 gattcggaga tcgcatcatt attcaggatt tccatttgcg ggatttggca gaagaaacgg
     1441 taatcgttcg actccagcgt ccctatcggt tgcggatcga gcgcattata tccgttcaga
     1501 tactgcatgc cccatacgta atgtccggca ggattggtag ttgattcacc gatacgaacc
     1561 aatctctttt gcaggcgcac caggtcataa aaaccggctt gtccttcaca gatcaactct
     1621 ttacggcgtt ccacatagat gtcttccagc aaagcttcgc ctccggcatt ggttgtcggg
     1681 gtagcattac gcgccacctg caaacggttc agcagattca gagcctcgcc ggagttaccc
     1741 ttttgggcag cagcctccgc cataatcagc agcatttcgg ctccgcgcat caggcagact
     1801 tccggacggg tggcgctttg aataacgctt ccgccgtctt caccataatg cttgtatttg
     1861 tcgaaagccc attttgtatt gatttccgta ttcgcattgt tcgtacgttt ccagaactgg
     1921 taacggtctt ctttttcttc aaatagtttc acaaactgct catccacgaa gtagtcaagg
     1981 aacgagtaga taggaccatc ggcataaccc tcgccgtagc tggcatcctg gttataccag
     2041 aaattgaact gcgtactacc gcccaggtta ttatcggcgg tatatttcat ggcccatacc
     2101 acttccgcat aattgccgga gatcatatcg tcgaaaccgg aacggtattg ttcgcgggtc
     2161 atcaactggc tgtgctggtc gtagacgatc ttggcttcat tgtaagcgcc gtcccagttc
     2221 tgcatcacca gataaacacg ggccaggatt cccgaacata ttttggagtt gatcagccac
     2281 atatcgtccg gattataatc ggcaagcaat gttttagccg tcgtcaggtc ggacacaatc
     2341 tgggtataga cttcctctac agtagaaaaa cctttatggg attcatcatc ggaagaggta
     2401 cgcaggatca ccccacgctt gcttttagct atcgcatacg tctgctggta attctggatc
     2461 agatggaaat actggattcc acgcatcgcc aacgcctggc ctttgatatg ttttttctgt
     2521 gtttcatcac cggcggcggc atccacattg gtcaggatga tattggcacg gttgatcaca
     2581 ttatagcaca tcgaccagat ttttgaggca tttccgtcag cctgtgtttt tgagttggaa
     2641 tactggtatg ctgttacctg atcacctccc atattggtat ggctgatcac gtcggcacca
     2701 ctcgcatcga catacatctg gaatccggga agaccggcat acacacggtc tcctttatca
     2761 gtattaaaat acagctgctt ataggctgaa gtcaatactt tttccaactg ggagacattc
     2821 cccagtacat cttcatcgtt tactttcacg taggagctgg ttgtcaggtc gtcgttacat
     2881 ccggtcaggg ccataccagc aaaaaccagg gacaggaagg atatatttat aaatcgtttc
     2941 ataaatatca ttttttacgt ttacaatgtg atttgaatac cgaccatata cagtcttctc
     3001 gaaccctgaa taccgttatc ggtttcagca ttaccgttat aactgttacc cattatacct
     3061 gtttcggggt ctgtgtagcg ttttttggca ggaccgaaag tcaacaggtt attaccggtt
     3121 acataaacac gcaggttttc taccagggcc ttgcgggtaa ggctcttagg cagcgtatag
     3181 cctaatgtca ggtttctcag acgccagtag tggttgtcga atacgaagtt atctgcatat
     3241 tttaccgtcg cgccatactg gttgtacgac caacgtggga taagcacatc cgcatcgccc
     3301 ggctgacgcc atctgtcctc aaccaactcc tgtatcacac cgacacccgg acggttcatg
     3361 atacgttctt tatatgtata gtccgatatt ttggaaccat aagaataata gaacatgaac
     3421 gacaggtcga tccctttgaa ctggaagtta ttggtgatag caccgaacac tttgggaatc
     3481 gcggagccac agtacacaaa atcgtctgtc gttacttctt cctgcttttc cgtacgtttc
     3541 caaccgccgt taccatcgcg gatcaaccag ccgggtactc cggtttccgg attaacaccg
     3601 tcgtactggg gagcgataaa ttcatacaga gacttgcctt cctccatctt gtaggtacag
     3661 gcggtaccag aataagtgta aggacctgta ggcaaataag tcacctcatt tttcagcgta
     3721 ctcatgttgg catcgatatc ccatctgaaa tctttcgttg taaggatatt cgcattcaat
     3781 gtgatttcaa tcccgctatt acgcaggtca ccgatattca tattataccc ggatgcacta
     3841 ccaacctggg cagagagagg cagttcctta taatacaaca agtcatggga agtacgggaa
     3901 taatattcca ctgtaccgct aagtcggttg aatacggaaa aatctaaacc gatattccat
     3961 tgctgattac tttcccactt caagtccggt gtcggatagg tagatggttt taaaccggat
     4021 ttcagataca ggtcatcact ttcataagta ccctggtatc cgtaaaggac ttcatcccct
     4081 gccttaccat tcgattcacg cacgatcagc ttatcattac cagtcgtacc gtaactacca
     4141 cgcaacgaaa ggttatcaat ccatttcagg tcttccataa aaccttcttt cgatattcgc
     4201 catgaaccgc ctgtcgacca gaatgtaccc cagcgatgat cggagctgaa acgggaagaa
     4261 ccatcctcac gaagtgaagc ggacaagtaa tacttattca agaagttata atcgacctta
     4321 ccaaagaacg aaagcagaga gtatttatca cgtccgccgg aaacaccgaa gttcttggtg
     4381 gtattcgata attcatattt acccagttcc atgatacctt caccccaacc ttgttcgtag
     4441 tgggagtccc aggtatacca ctcatgtccg accagacctg aaatcgtatg gtcaccaatc
     4501 atccattcac cagacaatac attattccag gtggtggaac gtttattgaa attataacgg
     4561 ctggcataac caccgtctgc cagtatagaa ataccataag gtgcagtctg tccgctgcca
     4621 tgtacggcgg aagtatattg catggtacga taccagtaat cgtcaatatt caaagccgaa
     4681 cggaatttca ggttgaaagg aagagtaaac tctgtattta cctgagcaga caggatatgc
     4741 cccatattgt tatcgaaact gtcatcgttc ggattatccc aataatcacc cgagttattc
     4801 aggatatggg caccaaagaa gttattggta tatttaccgt aactgtacat ccgttcccct
     4861 gttttttcag aaacgaccca accggtatta tcttcattac gtaaccaggg tgaagacaaa
     4921 gtcgtcgtaa agttagccgc acggctggca ccaccggaaa ggttctggcg atgacgcgaa
     4981 taagaaaggc taccggccac tttccaccaa tcgaacaact ctgtactcag gttggtacgg
     5041 aaagaataac gtttataata ctgccggtta ccatatccct ggtcgtccag ataaccgccg
     5101 gagaagaaat aggctgtttt tccaccattg gcctgaccac ttatatccac actataatcc
     5161 tggcgcagtt tacgggagaa gatagctttg tagacatccc aatcatcttc atcccagaca
     5221 tattccagat taggattcat gtaaggattc ccattgccgt catgcaatac gtaattttca
     5281 ttgatatgtc tgaacggagt gacataaatc agattaccat tcgaatcttt tgtagccttt
     5341 acctgtttgg tcaatgcctg cgacgaagca taatcgcccg cctgttgcat attcatgccg
     5401 tcataaagaa gggcatcata atacaaggca taccaggtat tttccagctg ctggtacgga
     5461 tcggcttttt tcggattctt gacagcatta tccgaagtac cccaacctcc gcggaagtta
     5521 atacgcggtt tttctgattt accccgcttg gttgtaatca ttacgacgcc gtttgctgca
     5581 cgcgaaccgt agagcgaagt ggccgccgca tccttcagca ccgtcatcga ttctatgtcc
     5641 gtaggattga tctgattcag ttttccatcg taaggcatcc cgtccacaat atataacgga
     5701 tcggcctttc cggacatgga agcaatacca cggatctcca cacgggcatc agctccgggg
     5761 ttaccctgta cattcacaac attcacaccg gcactcatcc cctgcaatgc ttccgcaaag
     5821 ccggagccca tgatcttttc gagtttttca gcttttacaa cggaggccga tccggtgaag
     5881 gttgatttct tagccgttcc ataggctacg acaacgactt catccaggtc ctgtgtcgca
     5941 tcacttaatt ttacatttaa aatagattgt ccgttccaag tgatctcctg agtggccagg
     6001 ccgacaaagg aaataacaat aaccgctccc cgccgaacat tatccagcgt aaactttcca
     6061 tcgatatcgg ttatcgtacc gatagtggtt cctttcacta caacagaagc tccggcgaca
     6121 ggtcccatct ggtcctctac caggccggtt accttattac cctgttgtac taccatcgtt
     6181 tccggacctg taggattggc agcaatcgca cctgccgcac ctaataatac agaaatcatt
     6241 agtgatctaa ttagttttga gttggtccac atagctaaat tcaagtcttt aattaaataa
     6301 aattaatcac aatagcgttc atttcattag aggttacact tttctaagat aaaagtgact
     6361 ggcatacatt tcaataaaat aaagttaact aaaacaaaga tatactgatc attacacaca
     6421 acatccttct atatttccac tctacaaact acagtatctc catcagcaaa tataacttat
     6481 cattatttaa tacaagcata attatgtata tttattgctc taataaatat attttaacca
     6541 ccatttaatt gattttttta tctaaaatcc acattcaaac aatgacatac atattgggat
     6601 gaaaaatcaa taacagttgc aatcaaaaac attttttaac cattaacgca ttacataaac
     6661 cataaaaaaa cggcaacccg aaaagccgga ttgccgtttt tatatcacaa aatgtttaac
     6721 tattaatgta tcaccattta ttagttgttt tcaggacgaa gtttacgaac aacagcacct
     6781 gcacgccaca tttcactttc gcgaagagca gccagttctt tttccagacc ttcacgatag
     6841 tcaggcttgc tgtttgtgtc gatagaacgc tgtgcttcgt taccgcaggc aacttcgcta
     6901 tacaacttct ggaacaccgg ttttgtagca tcgtggaacg ggcccatcca gtccaaagca
     6961 ccacgctgtg cagttgttga acagtttgca tacatccagt ccataccgtt ttctgcgaac
     7021 aacggcatca atgactgagt cagttcttct actgtttcat tgaatgcttc agaaggttcg
     7081 tgaccgtttt cacgcaaagt ttcgtactga gccaacagta atccctggat agctcccatc
     7141 aaagtaccac gttcgccggt caggtcagaa taaacttctt tcttgaatgt tgtttcaaac
     7201 aagtaaccag aaccaacacc gatacccagt gcaatcacgc gatcccatgc tttgcctgtt
     7261 gcatcctgga agattgcgta gcttgagttc agaccacgac cctgcaagaa catacggcgc
     7321 agtgaagtac ctgaaccttt cggagcaacc aggattacgt ctacatcagc aggagggatg
     7381 atgtttgtac gttctttgta agtgataccg aatccgtgag agaaatacaa agccttaccc
     7441 ggagtcaggt attttttgat gcgcggccaa acttcaatct gagcagcatc tgaaagcaga
     7501 tactggatga tagttgcttt ttcgcatgct tcttcgatat cgaacagtgt ttcgcccggt
     7561 acccaaccgt cagcaacggc cttttcccag gtcttaccac ctttacgttg tcctacaatt
     7621 acgttaaaac cgttgtcgcg caggttcagg ctctggccag gaccttgtac gccgtaacct
     7681 attacagcga ttgtttcgtc tttcaatact tctcttgcct tttccaacgg aaattcttcg
     7741 cgggttacta cgttttcgtc aacgccgcca aaattcatta ctgccatttt ctttttacta
     7801 ttaaaatgta tataaaataa tttgtttttc agatccaggt aacggcagcg cggctgatgg
     7861 ctttgccgtc gttacagatt gccatattat atttatcgag ggatacttcc tggttatgga
     7921 gagtcagctc catcccatac tttccttcgg actgataagc tatttcgaaa cggcttatct
     7981 ctttttctcg gaacagactg atatcgaaca agtcgagcag gtgttccatg tatttgatac
     8041 tgttcaggtg gccgtttacg tccaggtcac tatacttcac acggtaaggt tcgccggaag
     8101 tgttgttttc caccggagca attttacccg gtttttcaat cggacaggga cggtcggtga
     8161 tataagcact caggccctcc acatcgagca aggtcgggcg gcgggtttcc atatcgatag
     8221 ccgcccagat agagcgggca aagccaaagg tcttgccttc gccgttcacc agttcaaagc
     8281 aacggctggt aaacaactta ccgacctcat ccacccaggt atataaagtt acggattcag
     8341 acatggcagg ataagaagtc atctcgatag ccagacggga aagaacccag gcggtatgcc
     8401 tttcggtcat atcgttatat ccgaatccac ggtcggcggc atggcaagaa gcagcatgca
     8461 acaaataagt tccgatcata gggattgtaa tacgtccccg gaagtccgtc agataagact
     8521 ctgttacgaa atgaaattct cctactttgt tcttctccat aatttacttt atttacaaaa
     8581 tgtttcctta ttattctcag acatgttttt cctgcaactt cttttccatt gcagataaca
     8641 tgtcgctcag acgttctacc ttactcttcg ttatagcaac gcgtccggaa cggataaatt
     8701 gcaggacacc gatcgtctca ctcaattctt taaacaaagc ctgtgtctca tcataatgac
     8761 cactcttttc caacaccaca caatcctcat tcatttcaag gatacgggca ttgtacttac
     8821 ggatcagatc ctcaaccgtc cccatcttga taaagagttc ggtactcagt ttataaagag
     8881 cgatttcctg gtaaaccagg tcttcatccg tattataata ggctttcagg atatccacac
     8941 gcttgtcgat ctgttttacg accttgtcga tcgtatcctc gtcggcaaag gtagtaattg
     9001 taaacttatg tattcccttt atagcagagg gagaaacaga aagcgtctca atgttcagtt
     9061 gccggcgcgt aaagataaca gttatctgat tcagaagacc aacagtgttt tccgaaaaga
     9121 taataacggt atataattgt tttgtattca tagtttctcc tccttactta tcacccaaaa
     9181 tcatgtttgt cacgcttcct ccggccggaa ccatcggata taccatacca caagtttcca
     9241 cattggcaac caacatatag gcaccatcgt gattcaacat ttcagcaatc gcctcatcca
     9301 agtcttcccg tttatctacc gcacgggaag caataccaaa agccttggct atcgctacaa
     9361 aatccggatt cttcatgatg gtattcgaat accgttcgtt gaagaacagc tcctgccact
     9421 ggcgtaccat tcccaggaaa ttgttgttaa gaacgatgat ctttacattc agattttcct
     9481 gcatgatagt tcccaactcc tggatagtca tctggatacc accgtcgccg gtaaagaaac
     9541 agaccgtacg gtcaggcgct cccagcttcg ctccaatggc ggcgggaagg ccaaagccca
     9601 tcgttcccaa acctcctgaa gtaactacgc tgcgtgtttg tttatatttg aaatagcgaa
     9661 cacccatcat ctggttctga cctacatccg taaccagaat cgcatcatta tcggttgctt
     9721 cggaaacctt acggactact tcgcccattt tcagttggcc ttcggtagga tagagttctt
     9781 tttctattac cttattatat tcctcttttt catccggttc gaattcagca ttccattccg
     9841 gacgcttccg ttcttccagt aaagccgtaa tcatcggaat cgtatgcttg gcatttccca
     9901 gcactttcac gtcgaccggc acattctttc cgatctccga attgtcgata tccaggtgga
     9961 taatctttgc ctgcttggca taagtcttca ggtcgccggt tacgcgatca tcgaaacgca
    10021 taccgatagc aatcagcacg tcacattcgt ttgtcttgcg gttcggtccg acatttccat
    10081 gcatccccaa cataccttta tttaatggga agtccgaagg taatgcagac aagcccaata
    10141 cggtagaacc ggctggtata tcgtttttca acaagaattc tttcagttct tcttcagctc
    10201 ctcccaggat aaccccctgc cctaccagac agaatggctt tttggcatta tttatcaatg
    10261 aagcagccgc ctcgatacgt tcctccctga tatccggttc aggttggtaa ctacgaacat
    10321 aatccacttt ctgatactca taatctacca aacccacctg tgcatctttc gccaaatcca
    10381 gtaccacagg tcccgggcga ccggtcgatg cgatatagaa agcacgggaa acggcccaag
    10441 caatttcttc cgggcggcgt atctggtaag cccatttggt aatcggttgt gtgataccga
    10501 tcacatcaac ttcctggaaa gcatctgttc caagcagcgg agacggaacc tggccggcaa
    10561 tcaccaccat cggtgtactg tccatcagcg catcggcaat accagtgatg gtattggttg
    10621 ccccgggacc cgaagtaacc accgttactc ccacttttcc ggaaacacgg gcatatccct
    10681 gtgcagcatg tgttgcacct tgttcgtggc gcaccagaat atgttttaac tgatctctgt
    10741 aatcgtataa actatcgtaa attggtatcg cctgcccacc cggataaccg aagatagtat
    10801 ctactccttc agcgatcagc gctttcagca aagcttccga accggttatc ttttgtttgt
    10861 ccatctctaa aatatagtat ttggtgttta ttaatcttct actattcgta caccgccctt
    10921 atcggccgaa gcaaccatct ttgcatatgc tttcagtgct ttcgataccg tacgttggcg
    10981 gaaaggaggt gtaaaggctt ttgttccgcg ggcttcttcc gcttcacggc gtttggccag
    11041 ttcttcgtct gtcaccttta catgtatggt tctttcggga atattaattt cgataatatc
    11101 gccgtctttc actaagccaa tcgctccgcc tgcagccgct tcgggagaaa tatgtccgat
    11161 tgacaaaccc gatgttccac cgctgaagcg tccgtctgtg attaacgcac attctttacc
    11221 cagatgttta ctctttatat aagaggtagg atacaacatt tcctgcatac ccggaccacc
    11281 cttaggacct tcataggtga taacgacgac atcgccggag acgacttgat ctttcaggat
    11341 accttcgcaa gcggcatcct gcgaatcgaa tactttggca gggccggcaa aacggaagat
    11401 actttcatct accccggctg ttttaaccac acaaccgtcc tgtgcaatat ttccatacag
    11461 aacagccaga ccgccgtctt tcacataagc atgttccaca tcgcggatac atccggttgc
    11521 acggtcggta tccagttctt tataataact ttcctgcgat ccgagcacca gattgaaacg
    11581 gtgggccgga gcacttttat aaatattgat tgcttcttcc gttacattta cagaggtaat
    11641 gcagtattgg tcgatagcct cattcaaagt cagaccatcc gcacgtttca cggaaccgtc
    11701 caccagaccg gcttttacca gctcattcat aataccgata atacctccgg cacggttcac
    11761 atcttccaca tgataagaac aactcggagc cactttacag ataaccggtg ttttgcgtga
    11821 aagcatatcg atgtctttca ttgtaaaatc gacttccgct tcatgagcca cggccaacag
    11881 gtgaaggact gtattcgtcg atccccccat ggcaatatcc agcgacatag cattcagaaa
    11941 ggcctgacgg gtggcaatac tgcgaggcaa tacggaatca tcgccgtcac gataatattt
    12001 aaaggcatta tcaacaatca tcttcgcggc ttttttgaac aggcgggtac ggttggcatg
    12061 tgttgcaaca actgttccgt tgccgggaag agccaatcca atcgcttcgt tcagacagtt
    12121 catagagtta gccgtgaaca taccagaaca gcaaccgcag gtcgggcaag cggaacgttc
    12181 caccttttct acttgttcat cgctgataga atcgtcagcc gcttcaatca tggcgtcgat
    12241 caaatcgagt gcacgtccgt ccagattacc ggcttccatc ggaccgccgg atacaaagat
    12301 tgtcggaata ttcagacgca tactggccat cagcataccc ggagtaatct tgtcgcagtt
    12361 actgatacaa accattgcat cagccttatg cgcattcacc atatattcca cactgtcagc
    12421 aatgatgtcg cgggaaggca gagaataaag cattccgtcg tgtcccatag caataccgtc
    12481 atcaatagcg atcgtattaa attctgcggc aaagcaaccg agcttttcga tttccgcttt
    12541 tacctgctgt ccgatctcgt gtagatgcac atggcccggt acaaactggg taaatgaatt
    12601 cacaatggca atgatcggtt taccgaactg ttcttctttc atgccgttgg cacgccataa
    12661 tgcacgggct ccggccatac gtctgccttc tgtgctatag gagcttctta acggattctt
    12721 catcatatct gtttttatct tttagtcaat aaaaaagccc ttctctatat ggagaaaggc
    12781 ttaagaaata tcttttacga cttcacaact tcttacacac ctttctcctt acctactaat
    12841 gactagaagg accaccacga gaataatatg taatacattg ttcatcatct tttcttatcg
    12901 tctttatttt gtttgacgct gcaaatgtag aataataatt tgtacgagca aaggatttaa
    12961 aagaaaaatc ttactttttc tttcatttat caataaaaga gggcggttca tcttgcattt
    13021 taacagtatt attaaaatct acatcaatcg accgaccaac cggctatgtt ccgtgtttca
    13081 ttatcaaagt tcacccctat cttaaaaagt ttccgt
//
