LOCUS       c00396_gnlPro..         3685 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|GMKFPMID_396.
ACCESSION   c00396_gnlPro..
VERSION     c00396_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-05 15:25:17
            Original ID  :: gnl|Prokka|GMKFPMID_396
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 3685
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..3685
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[493:3684]"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      494..3684
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
     cand_cluster    1..3685
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /kind="single"
                     /product="TPP_AA_metabolism"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..3685
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="TPP_AA_metabolism"
                     /region_number="1"
                     /rules="(TPP_enzyme_C and not (PFL-like or PFL_6_pcresol or
                     PFL_9_tma or Gly_radical or Gly_430_pcre or Gly_8-9_TMA or
                     PFL_acetate1 or PFL_acetate2 or Gly_radical_scatole or
                     PFL_proline or PFL_toluene) and minimum(2, [ALS_ss_C,
                     AlaDh_PNT_C, Arginase, BKACE, BcrAD_BadFG, Beta_elim_lyase,
                     CPSase_L_D2, Cys_Met_Meta_PP, ELFV_dehydrog, GRDB,
                     Glu_syn_central, Glu_synthase, Gly_reductase, HAAA1, HG2B1,
                     HG2B2, HGD-D, HleuD1, HleuD2, HleuS1, HleuS2,
                     Homoserine_dh, ILVD_EDD, IlvC, Lactoyl-CoA1, Lactoyl-CoA2,
                     Lyase_aromatic, MAAL_C, OKR_DC_1_5_lysine,
                     OKR_DC_1_5_ornithine, OKR_DC_1_7_arginine, OKR_DC_1_C,
                     OTCace, PALP, Proline_reductase, Sacchrp_dh_C, TPL,
                     Thr_dehydrat_C, TnaA, Urocanase]) and not (POR or POR_N or
                     PFOR_II))"
                     /tool="gutsmash"
     CDS             complement(2..457)
                     /locus_tag="ctg396_1"
                     /transl_table=11
                     /translation="MEKNKVGEFHFVTESYLTDFRGRITIPMIGTYLLHAASCHAADRG
                     FGYNDMTERHTAWVLSRLAIEMTSYPAMSESVTLYTWVDEVGKLFTSRCFELVNGEGKT
                     FGFARSIWAAIDMETRRPTLLDVEGLSAYITDRPCPIEKPGKIAPVEN"
     CDS             complement(494..1048)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ALS_ss_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg396_2"
                     /sec_met_domain="ALS_ss_C (E-value: 4.5e-19, bitscore:
                     56.7, seeds: 685, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNTKQLYTVIIFSENTVGLLNQITVIFTRRQLNIETLSVSPSAIK
                     GIHKFTITTFADEDTIDKVVKQIDKRVDILKAYYNTDEDLVYQEIALYKLSTELFIKMG
                     TVEDLIRKYNARILEMNEDCVVLEKSGHYDETQALFKELSETIGVLQFIRSGRVAITKS
                     KVERLSDMLSAMEKKLQEKHV"
     CDS             complement(1061..2761)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg396_3"
                     /sec_met_domain="TPP_enzyme_C (E-value: 1.3e-51, bitscore:
                     162.5, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDKQKITGSEALLKALIAEGVDTIFGYPGGQAIPIYDSLYDYRDQ
                     LKHILVRHEQGATHAAQGYARVSGKVGVTVVTSGPGATNTITGIADALMDSTPMVVIAG
                     QVPSPLLGTDAFQEVDVIGITQPITKWAYQIRRPEEIAWAVSRAFYIASTGRPGPVVLD
                     LAKDAQVGLVDYEYQKVDYVRSYQPEPDIREERIEAAASLINNAKKPFCLVGQGVILGG
                     AEEELKEFLLKNDIPAGSTVLGLSALPSDFPLNKGMLGMHGNVGPNRKTNECDVLIAIG
                     MRFDDRVTGDLKTYAKQAKIIHLDIDNSEIGKNVPVDVKVLGNAKHTIPMITALLEERK
                     RPEWNAEFEPDEKEEYNKVIEKELYPTEGQLKMGEVVRKVSEATDNDAILVTDVGQNQM
                     MGVRYFKYKQTRSVVTSGGLGTMGFGLPAAIGAKLGAPDRTVCFFTGDGGIQMTIQELG
                     TIMQENLNVKIIVLNNNFLGMVRQWQELFFNERYSNTIMKNPDFVAIAKAFGIASRAVD
                     KREDLDEAIAEMLNHDGAYMLVANVETCGMVYPMVPAGGSVTNMILGDK"
     CDS             complement(2788..3684)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ILVD_EDD"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg396_4"
                     /sec_met_domain="ILVD_EDD (E-value: 4.5e-96, bitscore:
                     310.5, seeds: 918, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="PSCSYHVEDVNRAGGIIGIMNELVKAGLVDGSVKRADGLTLNEAI
                     DQYCITSVNVTEEAINIYKSAPAHRFNLVLGSQESYYKELDTDRATGCIRDVEHAYVKD
                     GGLAVLYGNIAQDGCVVKTAGVDESIFRFAGPAKVFDSQDAACEGILKDQVVSGDVVVI
                     TYEGPKGGPGMQEMLYPTSYIKSKHLGKECALITDGRFSGGTSGLSIGHISPEAAAGGA
                     IGLVKDGDIIEINIPERTIHVKVTDEELAKRREAEEARGTKAFTPPFRQRTVSKALKAY
                     AKMVASADKGGVRIVED"
ORIGIN
        1 tgttttccac cggagcaatt ttacccggtt tttcaatcgg acagggacgg tcggtgatat
       61 aagcactcag gccctccaca tcgagcaagg tcgggcggcg ggtttccata tcgatagccg
      121 cccagataga gcgggcaaag ccaaaggtct tgccttcgcc gttcaccagt tcaaagcaac
      181 ggctggtaaa caacttaccg acctcatcca cccaggtata taaagttacg gattcagaca
      241 tggcaggata agaagtcatc tcgatagcca gacgggaaag aacccaggcg gtatgccttt
      301 cggtcatatc gttatatccg aatccacggt cggcggcatg gcaagaagca gcatgcaaca
      361 aataagttcc gatcataggg attgtaatac gtccccggaa gtccgtcaga taagactctg
      421 ttacgaaatg aaattctcct actttgttct tctccataat ttactttatt tacaaaatgt
      481 ttccttatta ttctcagaca tgtttttcct gcaacttctt ttccattgca gataacatgt
      541 cgctcagacg ttctacctta ctcttcgtta tagcaacgcg tccggaacgg ataaattgca
      601 ggacaccgat cgtctcactc aattctttaa acaaagcctg tgtctcatca taatgaccac
      661 tcttttccaa caccacacaa tcctcattca tttcaaggat acgggcattg tacttacgga
      721 tcagatcctc aaccgtcccc atcttgataa agagttcggt actcagttta taaagagcga
      781 tttcctggta aaccaggtct tcatccgtat tataataggc tttcaggata tccacacgct
      841 tgtcgatctg ttttacgacc ttgtcgatcg tatcctcgtc ggcaaaggta gtaattgtaa
      901 acttatgtat tccctttata gcagagggag aaacagaaag cgtctcaatg ttcagttgcc
      961 ggcgcgtaaa gataacagtt atctgattca gaagaccaac agtgttttcc gaaaagataa
     1021 taacggtata taattgtttt gtattcatag tttctcctcc ttacttatca cccaaaatca
     1081 tgtttgtcac gcttcctccg gccggaacca tcggatatac cataccacaa gtttccacat
     1141 tggcaaccaa catataggca ccatcgtgat tcaacatttc agcaatcgcc tcatccaagt
     1201 cttcccgttt atctaccgca cgggaagcaa taccaaaagc cttggctatc gctacaaaat
     1261 ccggattctt catgatggta ttcgaatacc gttcgttgaa gaacagctcc tgccactggc
     1321 gtaccattcc caggaaattg ttgttaagaa cgatgatctt tacattcaga ttttcctgca
     1381 tgatagttcc caactcctgg atagtcatct ggataccacc gtcgccggta aagaaacaga
     1441 ccgtacggtc aggcgctccc agcttcgctc caatggcggc gggaaggcca aagcccatcg
     1501 ttcccaaacc tcctgaagta actacgctgc gtgtttgttt atatttgaaa tagcgaacac
     1561 ccatcatctg gttctgacct acatccgtaa ccagaatcgc atcattatcg gttgcttcgg
     1621 aaaccttacg gactacttcg cccattttca gttggccttc ggtaggatag agttcttttt
     1681 ctattacctt attatattcc tctttttcat ccggttcgaa ttcagcattc cattccggac
     1741 gcttccgttc ttccagtaaa gccgtaatca tcggaatcgt atgcttggca tttcccagca
     1801 ctttcacgtc gaccggcaca ttctttccga tctccgaatt gtcgatatcc aggtggataa
     1861 tctttgcctg cttggcataa gtcttcaggt cgccggttac gcgatcatcg aaacgcatac
     1921 cgatagcaat cagcacgtca cattcgtttg tcttgcggtt cggtccgaca tttccatgca
     1981 tccccaacat acctttattt aatgggaagt ccgaaggtaa tgcagacaag cccaatacgg
     2041 tagaaccggc tggtatatcg tttttcaaca agaattcttt cagttcttct tcagctcctc
     2101 ccaggataac cccctgccct accagacaga atggcttttt ggcattattt atcaatgaag
     2161 cagccgcctc gatacgttcc tccctgatat ccggttcagg ttggtaacta cgaacataat
     2221 ccactttctg atactcataa tctaccaaac ccacctgtgc atctttcgcc aaatccagta
     2281 ccacaggtcc cgggcgaccg gtcgatgcga tatagaaagc acgggaaacg gcccaagcaa
     2341 tttcttccgg gcggcgtatc tggtaagccc atttggtaat cggttgtgtg ataccgatca
     2401 catcaacttc ctggaaagca tctgttccaa gcagcggaga cggaacctgg ccggcaatca
     2461 ccaccatcgg tgtactgtcc atcagcgcat cggcaatacc agtgatggta ttggttgccc
     2521 cgggacccga agtaaccacc gttactccca cttttccgga aacacgggca tatccctgtg
     2581 cagcatgtgt tgcaccttgt tcgtggcgca ccagaatatg ttttaactga tctctgtaat
     2641 cgtataaact atcgtaaatt ggtatcgcct gcccacccgg ataaccgaag atagtatcta
     2701 ctccttcagc gatcagcgct ttcagcaaag cttccgaacc ggttatcttt tgtttgtcca
     2761 tctctaaaat atagtatttg gtgtttatta atcttctact attcgtacac cgcccttatc
     2821 ggccgaagca accatctttg catatgcttt cagtgctttc gataccgtac gttggcggaa
     2881 aggaggtgta aaggcttttg ttccgcgggc ttcttccgct tcacggcgtt tggccagttc
     2941 ttcgtctgtc acctttacat gtatggttct ttcgggaata ttaatttcga taatatcgcc
     3001 gtctttcact aagccaatcg ctccgcctgc agccgcttcg ggagaaatat gtccgattga
     3061 caaacccgat gttccaccgc tgaagcgtcc gtctgtgatt aacgcacatt ctttacccag
     3121 atgtttactc tttatataag aggtaggata caacatttcc tgcatacccg gaccaccctt
     3181 aggaccttca taggtgataa cgacgacatc gccggagacg acttgatctt tcaggatacc
     3241 ttcgcaagcg gcatcctgcg aatcgaatac tttggcaggg ccggcaaaac ggaagatact
     3301 ttcatctacc ccggctgttt taaccacaca accgtcctgt gcaatatttc catacagaac
     3361 agccagaccg ccgtctttca cataagcatg ttccacatcg cggatacatc cggttgcacg
     3421 gtcggtatcc agttctttat aataactttc ctgcgatccg agcaccagat tgaaacggtg
     3481 ggccggagca cttttataaa tattgattgc ttcttccgtt acatttacag aggtaatgca
     3541 gtattggtcg atagcctcat tcaaagtcag accatccgca cgtttcacgg aaccgtccac
     3601 cagaccggct tttaccagct cattcataat accgataata cctccggcac ggttcacatc
     3661 ttccacatga taagaacaac tcgga
//
