LOCUS       c00059_gnlPro..        13851 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|PELNKDKE_59.
ACCESSION   c00059_gnlPro..
VERSION     c00059_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-07 21:57:07
            Original ID  :: gnl|Prokka|PELNKDKE_59
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 13851
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..13851
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[2568:12571]"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and (minimum(2, [ACD1_car,
                     ACP_syn_III_C, AcetylCoA_hyd_C, AcetylCoA_hydro,
                     Acyl-CoA_dh_1, Acyl-CoA_dh_2, Butyrate_kinase,
                     CT_Propionyl_CoA1, CT_Propionyl_CoA2, CT_Propionyl_CoA3,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_2_CAF, CoA_trans_6_Glutaconate, E1_dh, ECH_1,
                     ECH_2, HBT, HBT_2, HCDH, HpaB, Ketoacyl-synt_C, Thiolase_C,
                     Thiolase_N, adh_short, adh_short_C2]) or FA_synthesis) and
                     not (PFL-like or PFL_6_pcresol or PFL_9_tma or Gly_radical
                     or Gly_430_pcre or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and not
                     (POR or POR_N))"
                     /neighbourhood="10000"
                     /product="TPP_fatty_acids"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      2569..12571
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and (minimum(2, [ACD1_car,
                     ACP_syn_III_C, AcetylCoA_hyd_C, AcetylCoA_hydro,
                     Acyl-CoA_dh_1, Acyl-CoA_dh_2, Butyrate_kinase,
                     CT_Propionyl_CoA1, CT_Propionyl_CoA2, CT_Propionyl_CoA3,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_2_CAF, CoA_trans_6_Glutaconate, E1_dh, ECH_1,
                     ECH_2, HBT, HBT_2, HCDH, HpaB, Ketoacyl-synt_C, Thiolase_C,
                     Thiolase_N, adh_short, adh_short_C2]) or FA_synthesis) and
                     not (PFL-like or PFL_6_pcresol or PFL_9_tma or Gly_radical
                     or Gly_430_pcre or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and not
                     (POR or POR_N))"
                     /neighbourhood="10000"
                     /product="TPP_fatty_acids"
                     /protocluster_number="1"
     cand_cluster    1..13851
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TPP_enzyme_C and (minimum(2, [ACD1_car,
                     ACP_syn_III_C, AcetylCoA_hyd_C, AcetylCoA_hydro,
                     Acyl-CoA_dh_1, Acyl-CoA_dh_2, Butyrate_kinase,
                     CT_Propionyl_CoA1, CT_Propionyl_CoA2, CT_Propionyl_CoA3,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_2_CAF, CoA_trans_6_Glutaconate, E1_dh, ECH_1,
                     ECH_2, HBT, HBT_2, HCDH, HpaB, Ketoacyl-synt_C, Thiolase_C,
                     Thiolase_N, adh_short, adh_short_C2]) or FA_synthesis) and
                     not (PFL-like or PFL_6_pcresol or PFL_9_tma or Gly_radical
                     or Gly_430_pcre or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and not
                     (POR or POR_N))"
                     /kind="single"
                     /product="TPP_fatty_acids"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..13851
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="TPP_fatty_acids"
                     /region_number="1"
                     /rules="(TPP_enzyme_C and (minimum(2, [ACD1_car,
                     ACP_syn_III_C, AcetylCoA_hyd_C, AcetylCoA_hydro,
                     Acyl-CoA_dh_1, Acyl-CoA_dh_2, Butyrate_kinase,
                     CT_Propionyl_CoA1, CT_Propionyl_CoA2, CT_Propionyl_CoA3,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_2_CAF, CoA_trans_6_Glutaconate, E1_dh, ECH_1,
                     ECH_2, HBT, HBT_2, HCDH, HpaB, Ketoacyl-synt_C, Thiolase_C,
                     Thiolase_N, adh_short, adh_short_C2]) or FA_synthesis) and
                     not (PFL-like or PFL_6_pcresol or PFL_9_tma or Gly_radical
                     or Gly_430_pcre or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and not
                     (POR or POR_N))"
                     /tool="gutsmash"
     CDS             26..1690
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) OAD_beta"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg59_1"
                     /sec_met_domain="OAD_beta (E-value: 1.4e-159, bitscore:
                     520.3, seeds: 229, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSLFDSLITFLQGMGVFSLSWQMVGMWGIAILLLYLGVAKQYEPL
                     LMVPIAFGALIANIPDNGMLITQLNQQVISSNEQGEVTATSLNNVGYLRVHVAPLQQAP
                     SKVPANLTTPESRSQYQEIMQQPMQVYPGSQLTVSKIKSVRESQEKAKADAARLGDDSL
                     TVDPNLKDFQNVTEDNGNEPVFLLTNGEGTTVVRQQGVNYFDTSGNRIPVDLKTQKLEP
                     LVVSAAGKYVAVGQHTQELLVTSIHGGLYDWIGLGIKAEIFPPIIFLGVGALTDFGPLL
                     AAPRTLLLGAAAQVGVAATFFMALFMGFTPNESASIGIIGGADGPTSIFLTMKLAPHLL
                     GAVAVAAYTYMSLVPLIQPPIMALLTTKKERLIRMKSLRTVSKSEKLFFAVLVTIVTIL
                     LIPDASPLIGMLMLGNFLRECKVTERLVQASQNEIINIVTIFLGTSVGLTMQGDRFLQS
                     ETLLIILLGIVAFGVATAGGVIAAKIMNLIWRKNPVNPLIGSAGVSAVPMAARVSHNVG
                     QKYDPSNYLLMHAMGPNVAGVIGTAVIAGYYIATLAK"
     CDS             1728..2507
                     /locus_tag="ctg59_2"
                     /transl_table=11
                     /translation="MNSAASFSTPPEEEGPCGDWTYHEWAEAFSTNDLARALPPGHIAV
                     CRVQTGGRGRFNRKWIGEEGGLWASFTVPLSAPEDTAAGVHWGHLPLVAGLALFNMLRG
                     MGLDSVRLRWPNDLLAGKSKLAGILVERPAENMAVIGIGINVFNDVSSIAGEIKDPPAR
                     LADLVRDCPSLHAVMASLGSHLNQVLSVFSHGGVPALQEGLSRAWAGERPVSILTDDET
                     VRGIFTGIDDQGNPVLSLPAGTVRTIPAHLINRLLEE"
     CDS             2569..4065
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_fatty_acids: AcetylCoA_hyd_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_fatty_acids: AcetylCoA_hydro"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg59_3"
                     /sec_met_domain="AcetylCoA_hyd_C (E-value: 6.8e-47,
                     bitscore: 148.9, seeds: 181, tool: rule-based-clusters)"
                     /sec_met_domain="AcetylCoA_hydro (E-value: 4.8e-44,
                     bitscore: 140.4, seeds: 5, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSYKVLTPEEAASLIKHGHHIGLSGFTPAGTAKAVTAALAKIAEA
                     EHEKGNPFQVSVFTGASTGDSCDGILSRAKAIRYRAPYTTNVDFRKAVNNGEIAYNDIH
                     LSQMAQEVRYGFMGNVDIAIIEACEVTADGKIYLTAAGGIAPTICRLADKIIVELNAAH
                     SKSAMGLHDVYEPLDPPYRREISIFKPSDRIGKPYIQVDPKKIVGVVETNWPDEARSFA
                     AADPLTDKIGQNVADFLAADMKRGIIPSTFLPLQSGVGNIANAVLGALGRDKTIPAFEM
                     YTEVIQNSVIGLIREGRVKFGSACSLTVTNDCLEGIYRDMDFFRDKLVLRPSEISNSPE
                     VIRRLGVISINTAIEADIYGNVNSTHIGGTKMMNGIGGSGDFTRNAYISIFTCPSVAKD
                     GKISAIVPMVSHHDHTEHDVNIIITEQGVADLRGKSPKERAQTIIENCVHPDYKNILWD
                     YLKLSDGKAQTPQSIRAALGMHAELARSGDMKNVDWAQYK"
     CDS             4185..4886
                     /locus_tag="ctg59_4"
                     /transl_table=11
                     /translation="MNWMIYPAARAFIKVCSVLFGTGAAAAVLIHLFMPFFLRSPRTAA
                     PFLLLGTGAELLSILSLSFLMFWGVRVLLASRGSRITRNLSMLAFLPALYALLIPFAGM
                     PVPSQYTEMDRVWEAVLLLSAVTSFFSFPYTAGYGAAGRRLFLAWGIAAAGCGLQSALF
                     FLAVLLRQFLSTAVPSLAAPVAWLAVLLSCGLEIMLAALSAILAQRLFKEVMSIASMPE
                     PIDPSMPGNRP"
     CDS             complement(5090..5953)
                     /locus_tag="ctg59_5"
                     /transl_table=11
                     /translation="MKGIVLAGGSGTRLHPVTLSVSKQLLPVYDKPMVYYPISVLMLAG
                     IREILVISTPRDLPLYRDLLGDGSRFGVSFKYREQPRPEGLAQAFIIGEEFIGKDSVAL
                     VLGDNIFYGRGLTEKLRRAAELTSGATIFGYQVHDPQRFGVVEFNEEGKAVSIEEKPPR
                     PKSDIAVTGLYFYDNRVVEIAKRIPKSSRGELEITSVNQEYLKQGLLRVEKLARGYTWL
                     DTGTHDTLLEASMFVRTLEHHQGFKVACLEEIAFNNGWISQETLRSQAGAMNNNGYGRY
                     LDELVK"
     CDS             complement(5963..7015)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GDP_Man_Dehyd"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg59_6"
                     /sec_met_domain="GDP_Man_Dehyd (E-value: 2.2e-99, bitscore:
                     322.6, seeds: 258, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKVIVTGGAGFIGSNLVRLLLERGHEVLNIDALTYAGNIHSLDGS
                     ADSPAYRFLHADVRDASLMRRTLREYAPDWVMHLAAESHVDRSIDDPGNFMTTNVMGTF
                     SMLQAALEYYRSLEGEKKERFRFHHISTDEVYGSLGKEGLFTESTPYRPHSPYSASKAS
                     SDHLVRAWHDTYGLPVLITNCSNNYGPYQFPEKLIPVVILKALGGEPIPVYGKGENVRD
                     WLYVGDHCEALLTVVSCGKPGETYNIGGNNEKTNLELVELLCSHLDELRPRPDGRSYRE
                     QISFVQDRPGHDLRYAIDASKIRRELGWTPRQDHSSGFRKTIQWYLDHEEWWRGILSGE
                     YRLERLGTNG"
     CDS             complement(7147..8091)
                     /locus_tag="ctg59_7"
                     /transl_table=11
                     /translation="MTSGGDAAGMNPAIKAAVDHARQLGMNPYVVYDGLEGLIDGKIKE
                     ATRELTNDMIYRGGTLLRSSRSKRFFDYEFRKQAYEHLKERNIDKLIIMGGDGSFRALN
                     DFFNDFEVPFAGIPATIDNDIAGTDYCLGVDTAQNVILDCIDSVRDTARSHHRAFVIET
                     MGRDCGYLAMTTALCSAADICIVPEIPYDLESIYKRLQPVINEEGSCIIAVVAEGTRVA
                     QYLTRWLTERAGMDTRLTVLGHVQRGGSPTARDRLMGTRFATRAVEALNNGDINQIMVY
                     HDGQYGYASLDSVAGQQYSVNQDIINLCRELSC"
     CDS             8220..8951
                     /locus_tag="ctg59_8"
                     /transl_table=11
                     /translation="MNDTAAAILKATAALRDGTEKLRFESPVHVTYNPLTYAWGPHEQY
                     VRTYGNGEKSHLFLGMNPGPFGMAQTGVPFGEVDAVVNWLHIRGEVGRPEHTHPKRPVE
                     GFGCPRSEVSGRRLWGLFAEAFGTAENFFRHNYVANYCPLIWMGATGANITPDKLPAEQ
                     RAAVDAVCMEHLLSLITILNPHTLVGVGAYATQKLRDAASRLPGKSFTIGTLLHPSPAS
                     PIANKLWPEHPIQQLKELGIL"
     CDS             9320..10786
                     /locus_tag="ctg59_9"
                     /transl_table=11
                     /translation="MAISDYIVTIGLEVHCQIKTKSKMFCSCETGFGFEPNTRVCPTCL
                     GLPGALPVLNEFAIERTLLTGLMLGCSSPEISQWDRKNYFYPDMAKNYQTSQLDLPLCL
                     GGEVPLYPWSYPNDVIKAGIPPFRTVKLTRIHLEEDAAKITHHANYSLIDYNRAGSALM
                     EIVSEPDIDTPEEAYAYLKSLQQILNYGDISDADMEKGQMRCDVNISLRPHGQKELGAK
                     VEMKNINSMSAVRRALHYEIQRQAEELDMGIPQIQSTRRWDDERGESVVMRTKEDAHDY
                     RYFPCPDLVPVRTAPLVEKVRGQIPELPQERQKRFMEEYGLSEYDANVLVGDLELARFF
                     EEAARGTASGKKIANWVINNISAVLNEKGMRPSECPVKPGAIRELIAIIDDGTVSNNQA
                     KDVFAKMWDEPALAAAQAAKLLGFEKADSSFLDGIVREVISANPDKVAEIQGGNEKLLN
                     WLTGQVMKAAKGKANPKIVTEALKKALSME"
     CDS             complement(10841..12571)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_fatty_acids: TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg59_10"
                     /sec_met_domain="TPP_enzyme_C (E-value: 2.1e-34, bitscore:
                     108.2, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MYRVADQIVEILEKAGVKRIYGIVGDSLNPVTDALRRRKTIEWIH
                     VRHEEVAAFAASAEAQLSGNLAVCCGSSGPGNLHLINGLFDAHRNHAPVLAIAFHIPQS
                     QVGMEYFQATHPEQLFKECSAYAELVSEASQAPSILMSAIQHAWARRDVGVVVLPGDIA
                     DAPAEMKNLVHPPSYTRENVVPEHESVSLLARMLDDHRRITFFCGAGCAGAEDKVVRLA
                     HRLKAPIAYTWRGKDHFEHDNPLGIGMTGLLGWGDAYKAMHESDMLVLWGTDFPYFNFI
                     PTKPEIVQIDRRGEVLGRRCRLDLGICGDVSVTAEALLNMVQEKTDSGHLDAALKRHAR
                     DVKEMNAYMEGNDKESPIRPEQLTTALNRHAASDAVFTVDTGTPCIWSARFLCATPGRR
                     TLASFNHGSMANAMPMAIGAQMEYPERQVIALCGDGGLSMLLGDLITIVQYRLPVKIVV
                     YNNDCLDFIQLEMQAAGLIPWQINLNNPSFAAVADAVGIKGFLLDKSSQVDQMVDMFLN
                     YPGAALLDAHVDRDALALPPYISMGQAADFSLAMMKQTLAGEVKQVWNTLAGNRKLFKP
                     "
     CDS             complement(12736..13464)
                     /locus_tag="ctg59_11"
                     /transl_table=11
                     /translation="MAIAACCSVPALASPGSLEPSAGTSYVAGTATTTEGIALGKDMTF
                     GSLSQSALPGSSIPYGGNFYASNYTISLWLDTSSLTEGTQTTLFGYYGTNVGQSYGTNA
                     LYLTSDAKLGMGDGNLNTSTGSFSQNRGDVSEASVVLGGGLLNVTLAVTGADQSQSVDV
                     YVNGSLLDTLSYNGNMNGNRSDIQSWINPNLTWGEIQWTDTKLSAEQIAGFAGLQVPEP
                     ASASLGILGLAVLMMRRRRS"
     CDS             13641..13772
                     /locus_tag="ctg59_12"
                     /transl_table=11
                     /translation="MNIKNKTQNRFFVEVLKLLYRNSNPFSQNRKNCNNSFIIEMLD"
ORIGIN
        1 ataaaccgct acaaaaatat tccctatgag tctttttgat tcattaatca cctttttaca
       61 ggggatgggc gtcttctccc tatcatggca gatggtaggg atgtggggca ttgccattct
      121 cctcctgtat ctgggtgtag ccaagcaata cgaaccgctc ctgatggttc ccattgcttt
      181 cggcgccctc attgccaaca ttccggataa cggaatgctc atcacccagc tgaaccagca
      241 ggtcatctcc tccaatgaac agggggaagt aaccgccacg tctctgaaca acgtggggta
      301 cctgcgcgtt cacgtggctc cgcttcagca ggctccctcc aaggtgccgg ccaacctgac
      361 cacgcctgaa tcccgttccc agtatcagga aatcatgcag cagcccatgc aggtttaccc
      421 cggcagccag ctgactgttt ccaagatcaa gtccgtgcgg gaatcccagg aaaaagcaaa
      481 agctgacgcg gcccgtctgg gcgacgacag cctgacggtg gaccccaacc tgaaggattt
      541 ccagaacgtg acggaagaca acggcaatga accggtcttt ctgctcacga acggagaagg
      601 gaccaccgtc gtccgccagc agggcgtcaa ttactttgac accagcggca accggattcc
      661 ggtggatctg aaaacccaga agctggagcc cctggtggtt tcagccgcag gcaaatacgt
      721 ggccgtaggc cagcataccc aggaactgct ggtcacctcc atccacgggg gcctgtatga
      781 ctggatcggg ctgggcatca aggctgaaat tttcccgccc atcatctttc tgggagtagg
      841 agccctgacg gacttcggcc cgctgcttgc cgctccgcgc accctgcttc tgggcgcagc
      901 ggcccaggtg ggcgtagccg ccacgttctt catggccctg ttcatggggt tcaccccgaa
      961 tgaatccgcg tccatcggca tcattggcgg cgctgacggc cccacctcca tcttcctgac
     1021 gatgaagctg gctccgcacc tgctgggcgc cgtggccgtg gccgcataca cgtacatgtc
     1081 cctggttccg ctgatacagc cgcccatcat ggcgttgctg acgaccaaga aggaacgcct
     1141 catccgcatg aaatccctgc gaacggtcag caagagcgaa aaactgttct tcgccgtgct
     1201 ggtaaccatt gtcaccattt tgctgattcc ggacgcatcc ccgctgatcg gcatgctgat
     1261 gcttggcaac ttcctgcgcg aatgcaaggt gacggaacgc ctggttcagg cctcccagaa
     1321 tgaaatcatc aacatcgtca ccatcttcct gggaacctcc gtggggctca cgatgcaggg
     1381 cgaccgcttc ctgcagtcgg aaacgctgct gatcattctt ctgggtatcg tcgccttcgg
     1441 cgtggcaaca gcgggcggag tgattgccgc caagattatg aacctcatct ggcgcaagaa
     1501 tccggtcaac cccctgatcg ggtccgcagg cgtctccgcc gtcccgatgg cagcccgcgt
     1561 ctcccacaat gtgggccaga agtacgaccc ctccaactac ctgctcatgc acgccatggg
     1621 tccgaacgtt gcaggcgtga tcggcaccgc agtcatcgcg ggttactaca tcgccactct
     1681 ggcgaaataa ccagaattga aaattactcc cggcctcggc ccgtcccatg aattccgcag
     1741 cctcattttc cacccctccg gaggaggaag gaccatgcgg cgactggact tatcatgaat
     1801 gggccgaggc tttttccacc aatgatctgg cccgagccct ccccccgggg catattgccg
     1861 tctgccgcgt tcagacagga ggccgcggca ggttcaaccg caaatggata ggggaggaag
     1921 gcggcctgtg ggcatccttc accgtccccc tgtccgctcc tgaggataca gcggccggcg
     1981 tgcactgggg ccatttgccc ctggttgcgg ggctggccct gttcaacatg ctccgcggca
     2041 tggggctgga ttccgtgcgc ctgcgctggc cgaacgacct gctggcgggc aaatccaaac
     2101 tggcgggaat actggtggaa cgcccggcgg agaacatggc cgtcatcggc atcggcatca
     2161 atgttttcaa tgatgtatcc tccatcgccg gggaaatcaa ggaccctccg gcaaggctgg
     2221 cggatcttgt tcgggactgc ccttccctgc acgccgtcat ggcttccctg ggcagtcatt
     2281 tgaaccaggt tctttccgtc ttttcccacg gcggcgtccc cgcccttcag gaggggctgt
     2341 cccgggcatg ggccggagaa aggccggttt ccattcttac ggatgacgaa accgtccggg
     2401 gcatttttac agggattgac gatcagggca atcctgtgct atcccttccg gccggcaccg
     2461 tccgcaccat tccggcgcac ctgatcaaca ggctcctcga agaatgagcc tgccgctccg
     2521 tttttacacg gggtttcttt cttttttcat ccaacaaaaa tcactgacat gagttacaag
     2581 gtactgacac cagaagaagc agcaagcctg atcaagcatg gccaccatat tgggctgagc
     2641 ggattcacgc ccgccggaac ggccaaggcc gttacggctg cgctggcaaa aatcgcagaa
     2701 gcggaacatg agaaggggaa ccctttccag gtgagcgtct tcaccggtgc ttccactggc
     2761 gattcctgcg acgggatcct ttcccgggcc aaggcaatcc gctaccgcgc tccctacacc
     2821 accaacgttg atttccgcaa ggcggtgaac aacggggaaa tcgcctataa tgacatccat
     2881 ttatcccaga tggcccagga agtgcgctac gggttcatgg gcaacgtgga catcgccatt
     2941 attgaagcct gtgaagtcac ggccgacggc aaaatttacc tgacggccgc gggcgggatc
     3001 gctcccacca tctgccgcct ggcagacaaa attatcgtgg aattaaacgc cgcccacagc
     3061 aagagcgcca tgggcctgca cgacgtttac gaacccctgg atcctcccta ccgccgcgaa
     3121 atctccatct tcaaacccag cgaccgcatc ggcaagccgt acatccaggt tgacccgaaa
     3181 aagattgtgg gcgttgtgga aaccaactgg ccggatgaag cccgttcctt cgccgcagcg
     3241 gatcccctga ccgataaaat cgggcagaac gtggccgatt tcctggctgc cgacatgaaa
     3301 cggggcatca ttccctccac gttcctgcct ctccagtccg gcgtaggaaa catcgcaaac
     3361 gcggtgctgg gcgccctggg ccgcgacaag acgattcccg cgttcgagat gtacacggaa
     3421 gtcatccaga attccgtcat cggcctgatt cgggagggcc gcgtgaaatt cggcagcgcc
     3481 tgctccctga ccgtgacgaa cgactgcctg gaaggcattt acagggatat ggactttttc
     3541 cgcgacaaac tggtgctccg tccctcggaa atatccaaca gcccggaagt tatccgccgt
     3601 ctcggcgtca tctccatcaa caccgccatt gaagccgaca tttacgggaa cgtcaactcc
     3661 acgcacattg gcggcacgaa gatgatgaac ggcatcggcg ggtccggcga cttcacgcgc
     3721 aacgcctaca tctccatttt cacctgcccg tccgttgcca aggacggcaa gatcagcgcc
     3781 atcgtcccca tggtttccca ccatgaccat acggaacatg acgtcaatat cattattacc
     3841 gagcaggggg tcgcggacct gcgcggcaag agcccgaaag aacgggccca gaccattatt
     3901 gaaaactgcg tccacccgga ttacaaaaac atcctctggg attacctgaa gctgtccgac
     3961 ggcaaagccc agacaccgca atccatcagg gccgctttgg gcatgcacgc cgaactggcc
     4021 agaagcggag acatgaagaa tgtcgactgg gcccagtata agtaattccg catgccgtca
     4081 ttcgcattgg catccatgaa ttcacgttaa cccctcagga ccgcttccgc aaagggagcg
     4141 gtccttttcc tttttcccat cccctctact ctcttctctt cgccatgaac tggatgattt
     4201 acccggcagc cagggctttc atcaaagtct gctccgttct tttcggcacg ggcgcagcag
     4261 cggcagtcct catccatctg ttcatgcctt ttttcctccg ctctccccgg acagccgcgc
     4321 ccttcctgct tttgggaaca ggggcggaac tgctctccat cctttccctg tccttcctca
     4381 tgttctgggg cgtcagagtt ctgctggcct cccgcggaag cagaataaca agaaatctga
     4441 gcatgctggc cttcctgccc gccctgtacg ccctcctcat tccgtttgcg ggcatgcccg
     4501 tcccatcgca atatacggaa atggacaggg tttgggaggc cgtcctcctt ctgtcggccg
     4561 tcacttcttt cttttccttc ccttatacgg cgggatacgg tgccgcaggc aggagattat
     4621 tcctggcctg gggcatcgca gcggcaggct gcggtttgca gagcgccctg ttttttcttg
     4681 ccgtcctgtt gcgtcagttc ctgtccaccg cagttccctc cctggcagcg cctgttgcat
     4741 ggctggccgt tcttctgtcc tgcggcctgg aaatcatgct ggcggccctt tccgctattc
     4801 tggcgcagcg cctgtttaaa gaggtcatgt ccatagcatc catgccggaa ccgattgatc
     4861 cttccatgcc gggcaaccgt ccctgacttt cctcccctcc gtttttaccg gcctgccgga
     4921 agagcaccct cattccccgg catgaaaggc ttttacggct ttgcgcaaaa agccgtccgg
     4981 aaatttccgc cggtggaacg gaatccgtat ggaaagcaac ccgccccacc ccggaaagcc
     5041 gcgggttcgc aggccccccc tcccgtttcc acgccgacgg cagacagccc tatttcacca
     5101 attcatccag ataacggcca taaccgttat tattcatggc tccggcctgg gagcgcagcg
     5161 tttcctggga aatccagccg ttattaaagg ctatctcctc caggcaggct accttgaacc
     5221 cctggtgatg ctccagagta cgaacgaaca tggaagcctc cagaagggta tcgtgcgtgc
     5281 ccgtatccag ccacgtatag ccgcgcgcca gtttttccac gcgcaacagg ccctgcttca
     5341 ggtattcctg attcacagag gtgatttcca actcgccgcg ggaagacttg ggaatccgtt
     5401 tggctatctc caccacccgg ttgtcgtaaa aatagaggcc cgtcaccgca atatccgatt
     5461 tgggcctggg cggtttttcc tcaatggaaa ccgccttccc ctcctcattg aattccacta
     5521 ccccgaaacg ctgcgggtca tgcacctggt aaccgaaaat ggtcgctccg ctcgtcagtt
     5581 cggcggccct cctcagcttc tccgtcaggc cgcgcccgta aaaaatattg tcccccagca
     5641 ccagggcaac ggaatccttt cctatgaact cctctccaat aataaaagcc tgagccagcc
     5701 cctccggcct gggttgttcc ctgtatttaa aggaaacgcc gaacctgctg ccgtccccca
     5761 gcaaatcccg gtacaggggc agatcccggg gcgtggaaat aacaaggatt tcccgtattc
     5821 cggccagcat cagcacggag atgggataat aaaccatcgg cttatcataa acgggcagca
     5881 attgcttgct gacggaaagc gtaacgggat gcagacgcgt gccgcttccc ccggccagaa
     5941 caataccctt catatcaaat tcctagccat tggttccaag acgttccagg cggtattccc
     6001 cggacaggat gccccgccac cattcctcat ggtccagata ccactgaatg gtctttctga
     6061 atccggaaga atggtcctgg cgcggagtcc accccaattc cctccgtatt ttggaagcgt
     6121 caatcgcata gcgcaggtca tggcccggcc tgtcctgcac aaaggagatt tgctcccggt
     6181 agctccggcc gtccggacgg ggccgcagtt catccagatg ggaacacagc agttccacca
     6241 gctccagatt ggttttctcg ttattgccgc cgatgttgta cgtttccccc ggttttccgc
     6301 aggaaacgac cgtcaacagc gcctcgcagt gatcccccac atacagccag tcccgcacgt
     6361 tttccccctt gccgtataca ggaatgggtt ccccgcccag cgctttcagg ataacgacgg
     6421 gtatcagctt ttccgggaac tggtaagggc cgtaattgtt ggaacagttg gtgatcagca
     6481 cgggcagccc gtacgtatcg tgccaggcgc gcaccaggtg gtcgctggag gccttgctgg
     6541 cggaatacgg ggaatggggg cgatacggcg tggactccgt gaacaggcct tcctttccca
     6601 gggagccgta cacttcatcc gtggaaatgt ggtggaagcg gaaacgctcc tttttctctc
     6661 cctccaggga acggtaatat tccagggcgg cctgaagcat ggaaaaagtg cccatgacgt
     6721 tggtggtcat aaaatttccc ggatcgtcaa tggaacggtc cacatgggat tccgccgcca
     6781 ggtgcatcac ccagtccgga gcgtactccc gcaaagtgcg ccgcatcagg gaagcgtccc
     6841 ggacgtcggc gtgcagaaag cggtatgccg gagaatccgc cgagccgtcc agtgaatgga
     6901 tgttgccggc ataggtcaga gcgtcaatat tcaggacttc atggccgcgc tccagcagca
     6961 gcctgaccag attggagccg atgaatccgg cgccgcccgt aacgataact ttcatagcac
     7021 tgttttcagg gaaagatgcg gcgccatcat acagcagcgg cgtttttttt caaaacaaat
     7081 ccgcccatgc cgcgggaacg tggcggcata ggcgggaaaa agcgggttcc gtaaccgctg
     7141 agacggctag cagctcagct cccggcaaag gttgatgata tcctggttca cggagtactg
     7201 ctgcccggct acggaatcca gggaggcata gccgtactgg ccgtcatgat acaccatgat
     7261 ctggttgatg tccccgttgt tcagagcttc cacggcgcgg gtggcaaaac gggtgcccat
     7321 caggcggtca cgggcggtgg gggaaccgcc gcgctgcaca tggcccagca cggtcaggcg
     7381 ggtatccatg ccggcgcgtt ccgtcagcca gcgggtcagg tactgcgcca cgcgggtgcc
     7441 ttccgccacc acggcaatga tgcagcttcc ttcctcattg atgacaggct ggaggcgctt
     7501 gtaaatggat tccagatcat acggaatttc agggacaatg cagatatccg ccgcgctgca
     7561 aagagcggtg gtcatcgcca gatagccgca gtcccggccc atcgtttcaa tcacgaaagc
     7621 gcggtgatgg gaacgggccg tatcacgaac ggaatcaatg caatccagaa tcacgttctg
     7681 ggccgtatcc acgcccaggc agtagtccgt tccggcaatg tcgttgtcaa tcgtagccgg
     7741 aataccggca aaaggcactt caaaatcatt gaaaaagtcg ttcagggcgc ggaaggaacc
     7801 gtccccgccc atgatgatga gcttgtcgat gttgcgttcc ttcagatgtt cgtaggcctg
     7861 cttgcggaat tcgtagtcga aaaagcgctt ggatcgtgag gaacggagga gagttccgcc
     7921 cctgtagatc atatcgttgg tcagttcccg ggtggcttcc ttgatttttc catcgatcag
     7981 cccttccaag ccgtcataaa caacgtacgg gttcatccca agctggcggg catgatccac
     8041 tgccgccttg atcgccgggt tcattccggc ggcatcaccg ccagatgtca taatggctat
     8101 tccactcata agtaataagg ttaacttgtc cggggggaaa tgttaccggg cggaacaaat
     8161 aatgcaagcg cggagttttt actggcgcaa taaacggcaa cacttcatga tgcggaggca
     8221 tgaacgacac tgcagcagcc attctgaaag ccacggccgc cctccgggac ggcacggaga
     8281 agctccggtt cgaatccccg gtccatgtta cctacaaccc tctcacctat gcatgggggc
     8341 cgcatgaaca gtatgtgcgc acctacggaa acggggaaaa gagccatctg ttcctgggca
     8401 tgaatcccgg ccccttcggc atggcccaga caggcgtccc cttcggggaa gtggacgccg
     8461 tcgtcaactg gctgcacatt cgcggagaag tcgggcggcc ggaacatacc caccccaaac
     8521 gtcccgtgga gggtttcggc tgccccaggt cggaagtcag cggccgccgc ctctggggac
     8581 ttttcgcgga agctttcgga actgcggaaa acttcttccg tcacaattac gtggccaatt
     8641 actgtccgct gatctggatg ggagccaccg gagccaacat tacgccggac aaactgccgg
     8701 cggaacagcg cgccgccgtg gacgcagtat gcatggaaca cctgctttcc ctcatcacca
     8761 tcctgaatcc ccacacgctg gtgggtgtgg gtgcctacgc cacgcagaag ctgcgggacg
     8821 ccgcctcccg gctccccggc aaaagcttca ccatcggcac gttgctccac ccaagccccg
     8881 ccagccccat cgccaacaag ctctggccgg aacaccccat ccagcagctt aaggaactgg
     8941 gcattttata aaaagagcgg aggaggtaga gtggaaagct ccgtgacatg gaaggaatca
     9001 ccagagcgac aggccggaaa tcggcagttc atcttgttct cctccaaatc tacatcgttt
     9061 tgaaggaata tccggccccc tttactggct tgatttgccc agggacacag ccttcctgac
     9121 ggaagaaaag cacgccggca tctaccggga cagagaagaa cttaaacgcc tccccacttc
     9181 caccacaaaa atcagcctcc ctccaaatca atcatcattc ttagactgaa aaccctccgc
     9241 tctcccccgc aggccttttt actggacagg gggaaaaggg ttccgtacag tttccgcgat
     9301 cttcaagcgt tccgaattta tggcaatttc agattacatc gtgaccattg gcctggaagt
     9361 ccactgccag atcaagacaa agagcaaaat gttctgctcc tgcgagaccg gctttggctt
     9421 tgaacccaat acgcgcgtgt gccccacctg cctggggctg ccgggcgccc tgcccgtcct
     9481 gaatgagttc gccattgaac gcacgctgct gaccggcctg atgctgggat gctccagccc
     9541 ggagatttcc caatgggacc gcaaaaatta tttctatccg gacatggcta aaaattacca
     9601 gacctcccag ctggatcttc cgctgtgcct gggaggggaa gtgcccctgt acccctggtc
     9661 ctatccgaat gacgtgatca aagccggcat cccccctttc cgcaccgtga agctgacccg
     9721 catccatctg gaagaagacg cggcgaagat tacccatcat gccaattatt ccctgatcga
     9781 ctacaaccgc gcggggtccg ccctgatgga aatcgtttcc gagccggaca tcgacacccc
     9841 ggaagaagcc tacgcctacc tcaagtccct ccagcagatt ttgaattacg gggatatctc
     9901 cgacgcggac atggaaaagg gccagatgcg gtgcgatgtg aatatttccc tgcgtcccca
     9961 cgggcagaag gaattgggcg ccaaggtgga aatgaagaac atcaactcca tgtccgccgt
    10021 ccgcagagcc cttcattatg aaatccagcg ccaggcggaa gaactggaca tgggcattcc
    10081 tcaaatccag tccacccgcc gctgggacga cgaacgcgga gaaagcgtcg tcatgcgaac
    10141 caaggaagac gcgcacgatt accgttattt cccctgtccg gatctggttc ccgtacgcac
    10201 ggccccgctg gtggagaaag tgcgcgggca gattcccgaa ctgcctcagg aacggcagaa
    10261 acgcttcatg gaagaatacg gcctgagcga gtacgacgcc aacgtgctgg tgggagacct
    10321 ggaactggca cgcttttttg aagaggcggc gcggggaacc gccagcggca aaaaaatcgc
    10381 caactgggtg attaacaaca tttccgccgt gctgaatgaa aaaggcatgc gcccgtctga
    10441 atgcccggtg aaacccggcg ccatccggga gctgatcgcc attattgacg acggcaccgt
    10501 ttccaacaac caggccaagg acgtattcgc caaaatgtgg gatgagccgg ccctcgccgc
    10561 agcgcaggcc gccaagctgc tgggctttga aaaggcggat tcctcttttc tggacggcat
    10621 cgtgcgggaa gtcatttccg ccaatccgga caaggtggcg gaaatacagg ggggcaatga
    10681 aaagctcctg aactggctta ccggccaggt catgaaggcc gccaaaggca aagccaaccc
    10741 gaaaatcgtg acggaagcgc tgaaaaaagc cctttccatg gagtgaccat aaacaaagag
    10801 ccgcttccct tgccgatgcc ggctccttgc ccgcagggca tcacggtttg aacagcttcc
    10861 tgtttccggc cagggtgttc catacctgct tcacttcccc ggccagcgtc tgcttcatca
    10921 tggcaaggga aaagtccgcc gcctggccca tactgatgta gggaggcagg gcaagggcgt
    10981 ccctgtccac atgcgcgtcc agcagagcgg cgcccggata attcaggaac atgtccacca
    11041 tctggtccac ctggctggat ttgtccaata aaaacccctt gatgccgacg gcatccgcca
    11101 cggcggcaaa agaggggttg ttcaggttga tctgccacgg aatcagcccg gccgcctgca
    11161 tttccaattg gatgaaatcc agacagtcat tgttatacac cacgattttc accggcagcc
    11221 tgtactggac aatcgtgatg agatccccca gcagcatgga caggccgcca tctccgcaca
    11281 gggcaattac ctgccgttcg gggtattcca tctgcgcccc aatagccatc ggcatggcat
    11341 tggccatgga gccatgattg aaggaagcca gcgtcctcct tcccggcgtg gcgcacagga
    11401 acctggcgct ccagatacag ggggtgccgg tatctaccgt aaatacggcg tcggatgccg
    11461 catgcctgtt cagggcggtc gtgagctgtt ccggccggat gggagactcc ttgtcatttc
    11521 cttccatata ggcgttcatc tccttcacgt ccctggcgtg gcgtttcagg gcggcatcca
    11581 aatgcccgga atccgtcttt tcctgcacca tgttcagcag agcttccgcc gtgacggaaa
    11641 catccccgca aatacccagg tccaggcggc agcggcggcc cagcacttca ccgcgcctgt
    11701 caatctgcac gatttcaggt ttggtgggaa tgaaattgaa ataggggaaa tccgtccccc
    11761 acaacacgag catgtcgctt tcatgcatgg ccttgtaggc atctccccat cccagcagcc
    11821 ccgtcatgcc gatgcccagg ggattgtcat gttcaaaatg atcctttccc ctccatgtgt
    11881 aggcaatcgg agctttcagg cggtgcgcga gccggacgac cttgtcttcc gctcccgcgc
    11941 agccggcgcc gcagaagaaa gtaatgcggc ggtggtcgtc aagcatccgt gccagaaggg
    12001 atacggattc atgctcagga acaacattct cccgcgtgta ggaaggagga tgcaccagat
    12061 tcttcatctc cgcaggggcg tccgcaatgt ctccgggcaa gacgacgacg cctacgtcgc
    12121 gcctggccca cgcgtgctga atggcggaca tcaaaatgga cggggcctgg gaagcttccg
    12181 aaaccagttc cgcatatgca ctgcattcct tgaaaagctg ttccggatgc gtggcctgga
    12241 aatattccat gcctacctgg ctctgcggga tgtggaaagc aatggccagc accggggcat
    12301 ggttccggtg ggcgtcaaac aggccgttga tcaaatggag gttcccgggg ccgctgctgc
    12361 cgcagcatac agccagattc ccgctcagct gggcttccgc gctcgcggca aaagccgcca
    12421 cttcctcatg ccgcacatga atccattcaa tggtcttcct cctcctcaaa gcgtccgtaa
    12481 cggggttcag gctatccccc acaatgccgt aaatccgctt aactcccgcc ttctccaaaa
    12541 tttcaacaat ctgatcggct accctgtaca tgcagattag acaccagcca acctccaacg
    12601 gattcattct tatgtgtcat cccctccatc ttttccgcac cggaaaaaat gcctgaggat
    12661 ttcccctgat atcataaagc cgccgccttt tcaggcagcg gcctatgaat ttaccagttc
    12721 tctggtggaa aaccgtcagg aacggcggcg gcgcatcatc agaacggcca ggcccaggat
    12781 tcccagagaa gccgaggccg gttccggaac ctgaaggccg gcaaaaccgg caatctgttc
    12841 cgcggaaagt tttgtatccg tccactgaat ttcaccccat gtaagattgg gattaatcca
    12901 gctttggata tcagagcgat ttccgttcat gttgccgttg taggacaacg tgtcaagcaa
    12961 ggaaccattc acatagacat ccacagactg gctttggtct gcgccggtaa cggccaaagt
    13021 cacgttaaga agacctcccc ccaaaacaac ggaagcttca gaaacgtctc cacggttttg
    13081 ggaaaaagag ccggtagaag tattcaagtt cccatctccc atgcccagct tggcatctga
    13141 cgtcagatac aaggcatttg tcccgtaact ttggcccaca ttggtgccat aatacccaaa
    13201 cagcgtggtc tgggttcctt ccgttaagga agaagtatcc agccagaggg agatcgtgta
    13261 attggaagca taaaaattac cgccgtaagg aatggaactg ccaggaaggg cactttgtga
    13321 gagacttcca aacgtcatgt cttttcccaa tgcaatacct tcggttgtcg tcgccgtacc
    13381 ggcaacgtaa gacgttccgg ccgatggttc taaagagccg ggagacgcca acgccggaac
    13441 ggaacaacac gccgcaatgg ccattaatgc taatgttttt ttcattttct gtgaatgatg
    13501 gactgagtag caatcagaga gatattcccc gccctctgta tatcggattc ccaatccgct
    13561 ctttttctcc cccacaggaa agatgagaac aagctttttc aatccgctaa aaaatataat
    13621 ataattacct tctatcactt atgaatataa aaaataaaac gcagaataga ttttttgtgg
    13681 aggttctgaa gttgctgtat aggaacagca atcccttttc gcaaaataga aaaaattgta
    13741 ataatagttt cataattgaa atgttagatt gacctcggat tgggaatccg gttgttttcc
    13801 ctcagccatc aaaaaaatca acataatgtt ttcatattca ataaaaatta a
//
