LOCUS       c00056_gnlPro..        13497 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|EBIJBGDG_56.
ACCESSION   c00056_gnlPro..
VERSION     c00056_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-05 15:58:09
            Original ID  :: gnl|Prokka|EBIJBGDG_56
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 4874
            Orig. end    :: 18371
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..13497
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[14874:18345]"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..13471
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
     cand_cluster    1..13497
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /kind="single"
                     /product="Fumarate2succinate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..13497
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Fumarate2succinate"
                     /region_number="1"
                     /rules="(Succ_DH_flav_C and FAD_binding_2 and (Fer2_3 or
                     Fer4_7 or SucD_FumR))"
                     /tool="gutsmash"
     CDS             complement(578..703)
                     /locus_tag="ctg56_5"
                     /transl_table=11
                     /translation="MKKKKLLKQLIVNFQHSLPAEVYPRTLVLPTDSGKIITVPD"
     CDS             complement(1061..2041)
                     /locus_tag="ctg56_6"
                     /transl_table=11
                     /translation="MKIKDIDLGPRPVFLAPMEDVTDPAFRLMCKHFGADMVYTEFVSA
                     DALIRSVGKTQQKLNISDEERPVAIQIYGRDTATMVEAARIVEQAHPDTLDINFGCPVK
                     RVAGKGAGAGMLQNIPLMLEITRAVVDAVKIPVTVKTRLGWDANSKIIVDLAEQLQDCG
                     IAALTIHGRTRAQMYTGEADWTLIGEVKKNPRMHIPIIGNGDITTPQRAKECFDLYGVD
                     AIMIGRASFGRPWFFKEVKHYLETGEELPPLSSEWRLNVLRQEVEDSVNLLDERRGILH
                     VRRHLAASPLFKGIPNFRDTRIAMLRAETKEELYRIFEEIEPLLP"
     CDS             2111..3403
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_U32"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg56_7"
                     /sec_met_domain="Peptidase_U32 (E-value: 4.2e-72, bitscore:
                     232.2, seeds: 96, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MMKHSISDFEIMAPVGSRESLAAAIQAGADSIYFGIENLNMRARS
                     ANTFTIDDLREIARTCDEHGMKSYLTVNTIIYDHDIPLMRTIVDAAKAAGISAVIAADV
                     AVMSYARQIGQEVHLSTQLNISNVEALRFYAQFADVVVLARELNLEQVAEIYRHIREEN
                     ICGPSGEQIRIEMFCHGALCMAVSGKCYLSLHEMNHSANRGACMQVCRRSYTVRDKETN
                     VELEVDNQYIMSPKDLKTIHFMNKMLDAGVRVFKIEGRARGPEYVRTVVECYKEAIRSY
                     LDDTFTDEKIARWDERLKTVFNRGFWDGYYLGQRLGEWTKNYGSAATERKIYVGKGIRY
                     FSNIGVAEFLVEAAEVSVGDKLLITGPTTGAEFVTLDEARVDLKPVQTVKKGQHFSMKS
                     VKIRPSDKLYKLVSVEELKKFKGLDVEKQRG"
     CDS             3381..3851
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HBT"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HBT_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg56_8"
                     /sec_met_domain="HBT (E-value: 3.8e-12, bitscore: 36.7,
                     seeds: 132, tool: rule-based-clusters)"
                     /sec_met_domain="HBT_2 (E-value: 8.2e-11, bitscore: 32.7,
                     seeds: 72, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MWRNNVAKYQIVNSPIVNMNYIYELPMKVRDYECDLQGIVNNANY
                     QHYLEHTRHEFLLSAGVSFAGLHEQGVDPVVARINMAFKTPLRSGDEFVSKLYMKKEGI
                     KYVFYQDIFRASDGKVCLKGIVETVCVVNGRLSDSELFDRLFAPYLNPCESV"
     CDS             3863..4981
                     /locus_tag="ctg56_9"
                     /transl_table=11
                     /translation="MNSDERICSIALTLCPGIGHIGAKRLIEGMGSAAEVFSRRKELPE
                     IMPGVNPGVVTALDCPAAFLRAEQEMEFVEKNRLSCLTLKDEAYPSRLRECEDAPIVLF
                     FKGNTDFNRLHVIDMVGTRRATDYGKQFCADFLRDLAVLCPDVLVVSGLAYGIDIHAHR
                     VALANHLPTIAVLAHGLDRIYPYVHRKTAIDMLAQGGLLTEFLTGTNPDKHNFVSRNRI
                     VAGMSDATIVVESAAKGGSLITAELAEGYHRDCFAVPGRVTDESSIGCNRLIRDNKAAL
                     IQSAEEFVQIMGWAVAEQPARTEGIQRNLFPELTEEEELVVRILMRQGDRHINAMVVEA
                     DIPVNRMSALLFELEMKGVVKAMVGGVYHLLT"
     CDS             complement(5001..5804)
                     /locus_tag="ctg56_10"
                     /transl_table=11
                     /translation="MKKPVLALLSIILLTAGCSQRPAATTKIPLTSAHRGAATIAPENT
                     MASVDSCIKYGVGNIECDVCISKDSVFYVLHDSTLDRTTNGTGAISQWLSTDIDTLDAG
                     SWFAPRFAGQRVLRLTDLLRKAKEHGLRITIDYRNGGLHQLLNLIKDEGMLENCNFTFS
                     KEYHAKCFRKMAPEVRTLQAYIKSEKDIEHVVKELHPDIAVVWIDSLTPQFVKKCREHN
                     LQVLALVLGLDDKTEENQKAVDLGVDIIATDHPEKFIMKYGQPSI"
     CDS             6233..6856
                     /locus_tag="ctg56_11"
                     /transl_table=11
                     /translation="MGKRIFIYVFWLLLFCMMSGQVIGQNKSVESHSHTCKTVLALKNN
                     LLYDLALAPNIEVELPLGKRWSLNVEYKCPWWSDSGCNFCYQLLSGGTEARYWLGNRHT
                     RGRLSGHFLGAYAEGGTYDFQLKKEKGYRGKYYAAAGITYGYVRPLARHLAIEFSVGIG
                     YLDTEYRKYTSYGNDLVWVSSGKYHFIGPTKAKVSLVWLLTSGR"
     CDS             6832..7836
                     /locus_tag="ctg56_12"
                     /transl_table=11
                     /translation="VASNVGEMSGMKDARHMILWLFFGLLPMLGSCDFRDMLDDYPVSG
                     VQIKLDWKGVTDKLPQTMRIIFYPKDTQGRKVESYLPAGGGEVKVPPGKYAVVAYNFNT
                     ESIQIRGDESYETIEAFTGHCTGLDVHEDMVWSPDPLYVVALDEVEIRQSDVALPLDWK
                     PEAVVDHYSFDIKVEGWDRISSIICHVDGLNGSYFIGNRACHLSEVPICVDTKRENGLL
                     WGYFSSFVLLKDTKTRADSPMLLTLKIVKRDKTVQEVKVDITEVIETAPPSGGGEEEPD
                     VGVPGSEIHIEVPVPEDKVVVDDLEPGTDEGDGGIGGDVDDWDDETDVELPVN"
     CDS             7882..8850
                     /locus_tag="ctg56_13"
                     /transl_table=11
                     /translation="MKKVLFLALAAAAVMSCSESEEIENAGQKAEIKLGTVVGNTTRAT
                     VTDLPELQKVGFTVYAYNTGATTMASVATFDAMKEFMAAVKVTYSAPDWSLTGETYYWP
                     MTDNLQFFAYGNPGTGALTYNQPAASAIYPSITYTVADVAAQTDLVAAKATDATKASNA
                     SGVSLKFGHILTQINFTVKAADALTYKLKTLTISGVHNKGTYGFDDSIWKSQEGTATYA
                     HTIDDGALEVNTTGVEVNTAWMLMPQTLDTNAKINVVYDIYEKDVLLDTVTSAIDLNDT
                     QAWGEGKKIRYTLTLANKAAKVTFVPEVGPWSTADDTNVEK"
     CDS             8915..9862
                     /locus_tag="ctg56_14"
                     /transl_table=11
                     /translation="MKVFGECFFYEYYLSIFVTATNKQIYLPMPNSSACRGKKQCAQCP
                     KAVDNAIIYASHLRGFHLPARKCEENIIIFLLKGEVLVNSKEYAGTVLHAGEFILQAIG
                     SKYEILAMTDVECVCYRFSKPEFFCEDRYNHIMKEVTPPLIFYPLTITPELQLFLESSK
                     AYLSEEKICREMLCFKRKELAFILGNYYSDYELSMLIHPLAQYTNSFHYFVLQNHAKVK
                     TVEELAQLGGYTVATFRRIFNSVFHQPVYEWMMERRKESVVYELRYTDASISEICYKYG
                     FESLPHFSNFCKKNFGASPRSLRAGNLSEVNGMS"
     CDS             complement(10001..10756)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Fer4_7"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Fer2_3"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg56_15"
                     /sec_met_domain="Fer4_7 (E-value: 1.5e-12, bitscore: 38.3,
                     seeds: 208, tool: rule-based-clusters)"
                     /sec_met_domain="Fer2_3 (E-value: 4.7e-26, bitscore: 81.2,
                     seeds: 38, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 5.5e-07, bitscore: 20.2,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDKNISFTLKVWRQKGPKAKGAFETYQMKDIPGDTSFLEMLDILN
                     EQLISEGKEPVVFDHDCREGICGMCSLYINGHPHGPATGATTCQIYMRRFNDGDTITVE
                     PWRSAGFPVIKDLMVDRTAYDKIMQAGGYVSVRTGAPQDANAILIPKPIADEAMDAASC
                     IGCGACVAACKNGSAMLFVSAKVSQLNLLPQGKPEALRRAKAMLSKMDELGFGNCTNTR
                     ACEAECPKNVSISNIARLNRDFIIAKLKD"
     CDS             complement(10790..12736)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: FAD_binding_2"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Succ_DH_flav_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1027:FAD binding domain (Score: 199.7; E-value:
                     2.8e-61)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg56_16"
                     /sec_met_domain="FAD_binding_2 (E-value: 7.7e-62, bitscore:
                     199.7, seeds: 62, tool: rule-based-clusters)"
                     /sec_met_domain="Succ_DH_flav_C (E-value: 1.3e-37,
                     bitscore: 118.8, seeds: 739, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTKIDSKIPEGPVAEKWTNYKAHQKLVNPANKRRLDIIVVGTGLA
                     GASAAASLGEMGFRVFNFCIQDSPRRAHSIAAQGGINAAKNYQNDGDSVYRLFYDTVKG
                     GDYRAREANVYRLAEVSNNIIDQCVAQGVPFAREYGGTLDNRSFGGAQVSRTFYAKGQT
                     GQQLLLGAYSALSRQVNVGTVKLYTRYEMEDVVLIDGRARGIIAKNLVTGKLERFAAHA
                     VVIATGGYGNAYFLSTNAMACNCSAAMACYRKGAWFANPAYVQIHPTCIPVHGDKQSKL
                     TLMSESLRNDGRIWVPKKLEDAKKLQEGTLQGKDIPEEDRDYYLERRYPAFGNLVPRDV
                     ASRAAKERCDKGFGVNNTGLAVFLDFSEAINRLGKDVVAQRYGNLFDMYEEITDVSPYE
                     NPMMIYPAIHYTMGGIWVDYELMTSIKGLFAIGECNFSDHGANRLGASALMQGLADGYF
                     VLPYTIQNYLADQITVPRFSTDLPEFAAAEKAVQEKIDWMMNIKGKKSVDSIHKELGHI
                     MWEYVGMGRTAEGLKEGLKKLKEVRKEFEKELFIPGDKEGMNVELDKAIRLYDFITMGE
                     LVAYDALNRNESCGGHFREEYQTEEGEAKRDDENYFYVACWEYQGSDEKEPVLLKEPLV
                     YEAIKVQTRNYKS"
     CDS             complement(12773..13471)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: SucD_FumR"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg56_17"
                     /sec_met_domain="SucD_FumR (E-value: 1.1e-129, bitscore:
                     419.9, seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MWLSNSSVGRKVVMSVTGIALVLFLTFHMAMNLVALVSANGYNMV
                     CEFLGANWYALVATVGLAALFIIHIIYAFWLTMQNRKARGSERYAVTEKPKTVEWASQN
                     MLVLGIIVIVGLGLHLVNFWAKMQLPELMHNMGMHADTLTLAYAANGVYHIQNTFSNPV
                     FVVLYLVWLGALWFHLTHGFWSSMQSLGWNNKVWINRWKCISNIYSTIVVLCFALVVVV
                     FFAKSLCGAC"
ORIGIN
        1 gggtgagcga gccgtttaat atggggtact tcttctatta tccgatgatt ctgctggtgg
       61 tggtgtggta tttcctttat cgtttcgacc ttttcgagaa ggtttcgttc gtcatcgtca
      121 ccgctttctt catctattac cttatttata tcttcgtccc cgttgccggg ccgcagttct
      181 acttccccgc cattggaagc gaccatgtgg cgcaaggtat ctttccgtcc atcggtgact
      241 atttccatca ccatcaggaa cttcttcccg gtccgggcta tgagcacggc ttcttctaca
      301 acctggtgga gagttcccag caggtgggtg agcgccccac ggctgctttt cccagttcgc
      361 atgtcggaat gtctacggta ctgatgatta tggcatggcg tggcagcaag cgtctgtttg
      421 cctgcttgtt tcctttctat ctgctgttgt gcggggctac ggtctatatc caggcacatt
      481 acctgataga ctctatcgtg ggtttcgtat cggctttcgg catttatatc ctggccacgt
      541 ggatgttcaa gcgatggttt gcgcagccga tgttccgcta gtcgggcacg gtgattatct
      601 ttccactgtc tgtgggcaat accaatgtac gcggataaac ttctgccgga agtgaatgct
      661 ggaagtttac gatgagctgt ttgagcagtt ttttcttttt cataaagaca tatttatggg
      721 attctttctt tcttgggaag acgaatatag ggacttgttt ctttctgcca aagaaacaat
      781 gttttttttc ttgcctcctt gttggtaagg ttttgccttc ccattggcaa ggctttgcca
      841 ccgcgttggc aaaactttgc cataggcatg gcaaaagttt gccaagggca aggcaagtgg
      901 ttggcaaaat ttcttgctga cagacagtga gttatgcgga tggcaacaaa gcgtgtcatc
      961 tgcgtctgga tccccccctc tcagaagcta ttcaagaagg ggcgtgagga tgattgctca
     1021 aatgtcggac tcgatggtaa aaatcgtatg cggttttctc ctatggcagc aacggttcta
     1081 tctcttcgaa gatgcggtac agttcctcct tcgtctctgc ccgcagcatg gctatccggg
     1141 tgtcgcggaa attgggaatc cctttgaaga gcgggcttgc tgccaggtgg cggcgcacgt
     1201 gcagtatgcc ccgtcgttca tccagcaggt tgacgctgtc ttccacttcc tggcggagta
     1261 cgttcagtcg ccattcggaa ctcagcggag ggagttcttc gcccgtctcc aaataatgct
     1321 tcacttcctt aaagaaccac gggcggccga agctggcacg gcctatcatg atggcgtcca
     1381 caccgtagag gtcgaagcat tctttggccc gttggggagt ggtgatatca ccgttgccga
     1441 tgatgggaat gtgcatgcgt gggttctttt tcacctcgcc gataagtgtc cagtccgcct
     1501 cgccggtata catctgggcg cgggtacggc cgtggatggt gagggcggca atgccgcagt
     1561 cctgcaactg ctcggcaagg tctacgatga ttttactgtt ggcatcccag cccaggcggg
     1621 tcttcacggt gacgggaatc ttcacggcat ctaccacggc acgagtgatt tccagcatca
     1681 gcggaatgtt ctgtagcata ccggcaccgg cacccttgcc ggcaacgcgc ttcacggggc
     1741 agccgaagtt gatgtccagc gtgtccggat gtgcctgctc cacaatgcgg gcggcttcta
     1801 ccatggtggc ggtgtcccgt ccgtatatct gtatggctac gggccgctct tcatcgctga
     1861 tgttcagttt ctgctgggtc ttgcctacgg agcgtatcaa ggcatcggca gaaacgaact
     1921 cggtatatac catgtctgct ccgaagtgct tgcacatcag gcggaaagca gggtcggtga
     1981 cgtcctccat cggggcgagg aatacggggc gtgggcccag gtctatatct ttaatcttca
     2041 taatctaagc ggatttgtcc gcaaaagtac agaaaaaagc ctacctttgc atactctaat
     2101 tcaaaaagaa atgatgaaac actcaatcag tgacttcgaa atcatggcac cggtaggctc
     2161 gcgcgaatct ctcgcagcag ccatacaagc aggtgccgac tccatctatt tcggtatcga
     2221 gaacctgaac atgcgtgccc gttcggcaaa taccttcact atcgacgatt tgcgggaaat
     2281 agcccggacg tgcgacgaac atggcatgaa gagctacctc accgtcaata ccattatata
     2341 cgaccatgac attccgctga tgcgtaccat tgtagatgcg gcaaaggcgg caggcatctc
     2401 ggcagtcatt gccgctgatg tggcagtgat gagctatgcc cggcagatag ggcaggaggt
     2461 acacctcagc acacagctca acatcagcaa cgtggaagcc ctgcgcttct atgcacagtt
     2521 tgccgatgtg gtggtgctgg cgcgtgagct gaatttggag caggtggcag aaatctaccg
     2581 acatatccgt gaggagaata tctgcggtcc cagtggagag cagatacgta tagagatgtt
     2641 ctgtcacggt gcgctttgca tggcagtcag cggaaagtgt tatctctcat tgcatgaaat
     2701 gaaccactcc gccaaccgcg gtgcctgcat gcaggtatgc cgccgtagtt atacggtgcg
     2761 cgacaaggag acgaatgtgg aattggaggt ggacaaccaa tacatcatgt cccccaaaga
     2821 cttaaaaact atccacttca tgaacaagat gctggatgca ggtgttcgtg ttttcaaaat
     2881 agaaggacgt gcccgcggac ccgagtacgt gcgcacggta gtggagtgtt acaaagaagc
     2941 catccgttcc tatctggacg atacattcac cgatgagaag attgcccggt gggacgaacg
     3001 tttgaagacg gtcttcaatc gtggtttctg ggacggctac tacttgggac aacgcttggg
     3061 cgaatggacc aagaactacg gctctgccgc tacggaacgt aaaatctatg tgggtaaggg
     3121 catccgctac ttctcaaaca tcggtgtggc agagttcctg gtagaagcag ccgaagtgag
     3181 cgtaggcgac aagttgctga ttacgggtcc cacaacgggt gccgaattcg tcactttgga
     3241 cgaggcacgc gtcgatttga aacccgtgca gactgtaaag aaaggccagc atttctcgat
     3301 gaaatcggtg aaaatacgtc ccagtgacaa actctacaag ctggtcagcg tagaggaact
     3361 gaagaagttc aaaggcttgg atgtggagaa acaacgtggc taagtatcaa atagtaaata
     3421 gtccaatagt aaatatgaat tatatctatg aacttcccat gaaggtgcgc gactatgaat
     3481 gcgacctgca aggcatcgtc aataatgcca attatcagca ttatctggag catacgcgcc
     3541 atgagtttct gttgagtgcc ggcgtcagct ttgccggact gcacgagcag ggggtagacc
     3601 cggtagtggc acgtatcaat atggctttca agactcccct gaggagtggt gacgagtttg
     3661 tctccaaact ctacatgaag aaggagggta tcaagtacgt cttttaccaa gatatcttcc
     3721 gtgcttccga cggcaaagtc tgtctcaaag gcatagttga aaccgtatgt gtggtgaacg
     3781 ggcggttaag cgatagcgaa ctgttcgacc gtctctttgc cccttatctc aatccgtgtg
     3841 aatctgtgta atctgtggtg gaatgaacag tgacgaacgg atttgcagca tagctctcac
     3901 actttgcccc ggtataggac atatcggggc aaagcgttta atagagggta tgggcagtgc
     3961 tgccgaagta ttcagtcggc ggaaggagct ccccgaaatc atgcccggtg tgaatccggg
     4021 ggtagtgacg gctcttgatt gtcccgctgc ctttctgcgt gccgagcagg agatggagtt
     4081 tgtagagaag aatcgtcttt cctgcctgac gttgaaggat gaggcttacc cttcccgcct
     4141 gcgtgaatgt gaagatgcgc cgattgtact tttctttaaa ggaaacaccg atttcaaccg
     4201 cctgcatgtc atcgatatgg taggtacacg tcgtgccacc gattacggca agcaattctg
     4261 tgccgacttc ctgcgcgatt tggccgttct ttgtcccgat gtgctggtag taagcggact
     4321 ggcctacggg atagatatcc atgcccatcg ggtcgctttg gcaaatcatc tccctaccat
     4381 tgctgtcctt gctcacggac tggaccgcat ttatccgtat gtccaccgga aaacagccat
     4441 cgacatgctg gcacaaggtg gactgctgac cgaattcctt accgggacga atccggacaa
     4501 gcataacttt gttagccgta accgtattgt ggcgggtatg agtgatgcta ccattgtggt
     4561 ggagtctgcc gcaaagggag gttcccttat cactgcagag ttggcagagg gatatcatcg
     4621 tgactgcttt gccgttccgg ggcgtgttac ggacgaatct tccatcggtt gtaaccggtt
     4681 gatacgcgac aacaaggccg cccttatcca gagtgcggaa gagtttgtgc agattatggg
     4741 ctgggccgta gcggagcagc ctgcccggac agaaggtatt cagcgtaatc tctttccgga
     4801 actgacggaa gaggaggagc tcgttgtgcg tattcttatg cggcagggag accgccatat
     4861 caatgcgatg gtggtggaag cggatatacc cgtcaaccgg atgagtgcct tgctttttga
     4921 attggagatg aaaggagtgg tcaaggcaat ggtgggcggt gtctatcatt tgctgacctg
     4981 agcgcggcag gtctcttgcc ttatatggac ggttgcccgt atttcatgat gaacttttct
     5041 ggatggtccg tcgctatgat gtctaccccc aggtcgaccg ccttctggtt ctcttccgtc
     5101 ttgtcgtcca gccccaggac gagtgccagt acctgcaggt tgtgctcacg gcatttcttt
     5161 acgaattgcg gggtaaggga gtcaatccag acgacagcga tgtcgggatg cagttccttt
     5221 acgacatgct ctatgtcttt ttcacttttg atgtaggctt gcagggttct tacctcgggt
     5281 gccatctttc tgaagcattt ggcatgatac tccttgctga aggtgaagtt gcagttttcc
     5341 agcatgcctt cgtcctttat caagttcagt aattggtgca gaccgccgtt gcggtagtcg
     5401 atggtgattc ttaaaccgtg ctctttggcc ttgcgtagca ggtcggtaag gcgtagtacc
     5461 cgctgtccgg caaatcgggg cgcaaaccaa gagccggcat ccagtgtgtc gatgtcggtg
     5521 gacagccatt gggagatggc accggtaccg ttggtggtac ggtcgagggt ggaatcgtgc
     5581 agtacgtaga agacactgtc cttactgatg cagacatcgc attctatatt gcctacaccg
     5641 tatttgatgc acgaatctac ggatgccatt gtgttttcgg gagcgatggt ggcggcacca
     5701 cggtgtgcgc tggttagggg tatcttggtg gtggcagcag gccgttggga acatcctgcg
     5761 gtaagtagga ttatggaaag caatgcgagt accggttttt tcataatggg ctcaagtggt
     5821 gatgttttct tctttaacag ttataaaagc catcgaagat agctattttt tgtcattcgg
     5881 agaaacgtat gggcataaaa aaaggagtac cgctgtactc caacctttgt taaccttaaa
     5941 tctaatacta tgaaaaaaat cacattacaa atgtaaggtt cccgttgtta tcttccaaat
     6001 ttcagaatgt tcctgctact tcttttgtat ttctttcact gaattttact gttttcgcac
     6061 acggattgac tttttgagag agaagaatct attcacagcg tcccggataa ggcagaagtt
     6121 gcaaatctgt ttcaatcgtt tcacagaacc tttcagcctt tgaaaagagt gatggaaagt
     6181 gatttttatt cggtaattat cttctacttt tgtttgtata caacgcgaaa ttatgggaaa
     6241 acgcattttt atatatgtct tttggctact ccttttttgc atgatgtcgg ggcaggtaat
     6301 agggcagaat aagtcggtag aatcccatag ccatacttgt aaaacggtgc tggcgttaaa
     6361 aaataatttg ctttacgacc tggccttggc tccgaacata gaagtggagc tgccattggg
     6421 aaagaggtgg tctttgaatg ttgagtacaa atgcccttgg tggtctgaca gcggatgtaa
     6481 tttctgctat cagctccttt cgggagggac agaggcgcgt tactggttgg gaaaccgcca
     6541 tacgcgcgga agattgtccg gacacttcct gggagcatat gccgaaggag gtacctatga
     6601 ttttcagttg aaaaaggaga agggataccg ggggaagtat tacgcagctg caggaataac
     6661 ttatggatac gtgcgtccac tggctcggca tctggcgatt gaattcagtg tgggcattgg
     6721 atacttggat acggagtaca ggaaatatac ttcttatgga aatgacttgg tttgggtcag
     6781 cagtggaaag tatcacttta tcgggccgac aaaagcaaaa gtttctttgg tgtggcttct
     6841 aacgtcgggg agatgagtgg tatgaaagat gcacggcata tgattctctg gctgttcttc
     6901 gggctgttgc caatgctggg aagctgtgac ttccgcgata tgctggatga ttatcccgtt
     6961 agcggagtac agattaaact ggattggaaa ggggtgacgg ataagctgcc gcagaccatg
     7021 cggattatct tctatccgaa agatactcag gggagaaagg ttgaaagtta tctgcctgcc
     7081 ggagggggtg aggtgaaggt accgccgggg aagtatgcgg tggtggccta taacttcaat
     7141 acggagagta tacagatacg gggcgacgag agttatgaga cgattgaggc ttttacggga
     7201 cactgtacgg ggctggatgt acacgaagat atggtttggt cgcccgaccc tttgtatgtg
     7261 gtggctttgg acgaggtgga aataaggcag agtgatgtgg cgcttccgtt ggactggaag
     7321 ccggaagcgg tagtggacca ttattccttt gatataaagg tggaaggatg ggatagaata
     7381 tcgagcatca tctgccatgt ggacggcttg aacggaagtt actttatagg caaccgtgct
     7441 tgccatttga gcgaggtacc tatatgtgtg gatacaaagc gtgaaaacgg gcttttatgg
     7501 gggtatttct ccagttttgt attactgaaa gataccaaga cccgtgcgga tagtcctatg
     7561 ttgctgacac tgaagattgt gaaacgagat aaaacggttc aagaggtgaa ggtagacatc
     7621 acggaagtga ttgaaacagc tcctccctcg ggaggaggcg aagaagaacc tgatgtgggc
     7681 gttcctgggt cggaaatcca tatcgaggtt cccgtaccgg aggacaaggt tgtggtggat
     7741 gatttggaac cgggaaccga tgaaggagat ggagggattg gtggcgatgt ggacgattgg
     7801 gatgatgaga cggatgtgga gctaccggtg aattgatagc aaacagacaa ataaatatat
     7861 taactttaat aacagacaat tatgaagaag gttttatttt tggctttggc tgcagcagca
     7921 gtaatgagtt gctcggaaag tgaggagata gagaatgccg gacaaaaggc ggagattaaa
     7981 ttgggaacag tagtgggtaa cactacgaga gccacagtga ctgatttgcc ggaattgcag
     8041 aaggtagggt tcactgtgta tgcttataat acgggagcaa caacaatggc ctctgttgcg
     8101 acttttgatg cgatgaagga attcatggca gctgttaagg taacttatag tgctcccgac
     8161 tggagtttga ctggggaaac atattattgg ccaatgacgg ataacttgca gttctttgct
     8221 tacgggaatc cgggtaccgg ggccttgacg tacaatcaac cggctgctag tgctatatat
     8281 ccttccatta cttatacggt agcggatgta gctgcccaaa cggacttggt agccgcgaaa
     8341 gcgacggatg caaccaaggc atcaaatgcc agtggggtat ctttgaaatt cggccatata
     8401 ctgacccaaa taaatttcac tgtcaaggca gccgacgctt tgacttataa actgaaaaca
     8461 cttacaatat ccggtgtgca caataaagga acttatggtt ttgatgattc aatatggaag
     8521 tcacaggaag gaacagccac ttatgcacat acgattgacg atggtgcatt ggaagtgaat
     8581 acaacgggtg tggaagtgaa tacagcctgg atgttgatgc cccagacgtt ggatacgaat
     8641 gccaaaatca atgttgtcta tgacatctat gagaaagacg ttcttcttga tactgtaact
     8701 tccgccattg acttgaatga tacacaagcc tggggtgaag gcaaaaagat acgttatacg
     8761 ctgacgctgg ccaataaggc ggcaaaagta acctttgtac ctgaagttgg tccatggagt
     8821 acggctgatg atacgaacgt ggaaaaataa aacggcactg tccgcaataa aaaactgaat
     8881 tacttctatt ttattcattc cccgaaactt ctttatgaaa gttttcgggg aatgtttctt
     8941 ttatgagtat tatttatcta tttttgtcac tgcaacaaac aaacaaatct acttgccgat
     9001 gcccaactct tctgcttgca gaggtaaaaa acaatgcgct caatgtccca aggctgtgga
     9061 caatgcaata atatatgctt cccacctcag aggattccat ctgccggcgc gaaagtgtga
     9121 ggaaaatatt ataattttcc tgctgaaagg agaagtgctt gtcaacagta aggagtatgc
     9181 gggaactgtg ttgcatgcag gtgagttcat ccttcaagct attggttcca agtacgaaat
     9241 acttgccatg acggatgtgg aatgcgtttg ttaccggttc agtaagcctg aattcttctg
     9301 tgaggaccgg tataaccata ttatgaaaga ggttacccct ccattgatat tctatccttt
     9361 gaccattact cccgagttgc agctctttct ggaaagttcc aaggcctatt tgtccgagga
     9421 gaagatttgc cgggaaatgc tttgtttcaa acggaaagaa cttgctttca ttcttggaaa
     9481 ttactactcc gactatgagc tttccatgct gatacatcct cttgcccagt atactaattc
     9541 cttccactac tttgtcttgc agaatcatgc caaagtcaag acggtagagg aacttgccca
     9601 gttgggagga tatacagtag ctactttccg gcgtatattc aattctgttt ttcatcaacc
     9661 ggtgtacgag tggatgatgg aacggaggaa ggaaagcgtg gtttatgaac ttcgttatac
     9721 ggatgcttct atatcagaga tttgctataa atatggcttt gaatcgctgc ctcatttttc
     9781 caatttctgc aaaaagaatt tcggggcttc tccccgtagc ttgcgtgccg gcaatttatc
     9841 tgaagtaaac ggcatgtcat aaaaaaactc ctccggcggt ttcccggcag aggagtctct
     9901 tgtgatatta atcaaatata gtgaaagctg agtgataaat ctgagcttgc tcaaaaggtt
     9961 tatccgaagc gcatcctata ttatttgcag aaagaccgga ttagtctttc agtttcgcaa
    10021 tgataaagtc gcggttcagg cgagcaatgt tgctgatgga aacattcttc gggcattcag
    10081 cttcgcacgc acgagtgttt gtacagttac cgaaaccgag ttcgtccatc ttgctcaaca
    10141 tagccttggc acggcgcaat gcttccggtt tgccttgggg caacaggttc agctggctca
    10201 ccttggcaga aacgaacagc atagcagaac cgttcttaca agcagccaca caagcaccac
    10261 aaccgataca gctggcagca tccatagcct cgtcagcgat gggcttcgga atcaggatag
    10321 cgttggcatc ctggggagca ccggtacgta cgctgacgta gccgcctgcc tgcataatct
    10381 tgtcgtaggc cgtacggtcg accatcaagt ccttgataac cgggaaaccg gcagagcgcc
    10441 acggttcaac agtgatggta tcgccgtcgt tgaaacgacg catataaatc tggcaagtcg
    10501 tagcgccggt tgcaggaccg tgggggtgtc cgttgatgta gagcgaacac ataccgcaga
    10561 taccttcgcg gcagtcgtgg tcgaatacaa ccggttcttt accttcagaa atcagctgtt
    10621 cgttcaagat atccagcatt tcgaggaatg aagtatcgcc cgggatatct ttcatttggt
    10681 atgtttcaaa agcgcctttt gctttcggac ccttctggcg ccataccttg agcgtaaatg
    10741 atatattttt atccattttc tttaattctt taaatgttca acttcccgat tagcttttgt
    10801 agttacgagt ctgtaccttg attgcttcgt aaaccagcgg ctctttcagc aataccggtt
    10861 ccttttcgtc agaaccctga tattcccagc aagccacgta gaagtagttt tcatcgtcac
    10921 gcttggcttc gccttcttca gtctgatatt cttcacggaa gtgaccgccg cagctttcgt
    10981 tacggttcag tgcatcgtaa gcaaccagct cgcccatagt gatgaagtcg tacagacgga
    11041 tagccttgtc gagttctaca ttcatacctt ccttgtcgcc cgggatgaac agttctttct
    11101 cgaactcctt gcggacttct ttcagcttct tcagaccttc cttcaagcct tcggccgtac
    11161 gtcccatacc tacatattcc cacataatgt ggcccagttc cttgtggata gagtctacag
    11221 acttcttacc cttgatgttc atcatccagt caatcttctc ctgaacggcc ttttctgcag
    11281 ctgcaaattc gggcaggtcg gtagagaaac ggggaactgt aatctggtcg gccagatagt
    11341 tctggatagt gtaaggcaat acgaagtaac catcggccag accttgcatc agggcggaag
    11401 caccgaggcg gtttgcaccg tggtcggaga agttacattc accgatggcg aacagtccct
    11461 tgatggaggt catcagttcg tagtcaaccc agataccacc catggtatag tggatagccg
    11521 gataaatcat catcgggttt tcgtatgggc tgacatcagt gatttcttca tacatatcga
    11581 agaggttgcc gtaacgttgt gcaacgacat ctttacccag acggttgata gcttcggaga
    11641 agtcaaggaa tacggcaaga ccggtgttgt tcacgccgaa gcccttgtcg cagcgttctt
    11701 tggcagcgcg gctggcaacg tcacgcggaa cgaggttacc gaatgccgga taacggcgtt
    11761 ccaggtagta gtcgcggtct tcctcgggaa tatcttttcc ttgcagtgta ccttcctgca
    11821 gtttcttggc atcttccagc ttcttcggaa cccagatacg accatcgtta cgcagagatt
    11881 cggacatcaa agtcagctta gactgcttgt caccgtgaac cgggatacaa gtggggtgaa
    11941 tctgtacgta agcagggttg gcaaaccagg cacctttacg gtagcaagcc attgctgcag
    12001 agcagttaca tgccattgca ttggtagaaa ggaagtaggc attgccgtaa ccaccggtag
    12061 cgattaccac agcgtgggcg gcaaaacgtt ccaatttacc ggtaacgagg ttctttgcaa
    12121 tgataccgcg ggcacgtccg tcaatgagga caacgtcttc catttcgtag cgggtataca
    12181 gtttcacagt gcctacgttc acctggcggc tcaatgcaga gtatgcaccc agcaacagct
    12241 gctgtccggt ctgacccttg gcatagaaag tacgggatac ctgagcacca ccgaaagaac
    12301 ggttgtccag tgtaccgccg tattcgcggg cgaaaggaac accttgtgca acgcattggt
    12361 cgataatatt gttggatact tcagccagac ggtaaacgtt ggcttcgcgg gcacggtagt
    12421 cgccaccctt tactgtatcg tagaacagac ggtatacaga gtcaccgtcg ttttggtaat
    12481 tcttagcagc attgatacca ccttgtgcag cgatggagtg tgcacggcgc ggagagtcct
    12541 ggatgcagaa gttgaatact ctgaaaccca tttcgcccag agaggcggca gcactggcac
    12601 cggcaagtcc ggttcctact acgatgatgt ccagacgacg tttgttggca gggtttacta
    12661 atttttggtg agccttataa ttggtccatt tctcagccac cggtccttcc ggtattttag
    12721 aatctatctt agtcataatg caatttacaa tttagtcatt tacaatttga atttagcaag
    12781 cgccgcacaa tgattttgca aagaatacga caactaccag agcgaagcag aggacaacga
    12841 tagtagaata gatgttggag atacatttcc aacggttaat ccatactttg ttgttccagc
    12901 ccaaagactg catggagctc cagaaaccgt gagtgaggtg gaaccacaat gcgcccagcc
    12961 aaacgaggta aagcactacg aataccggat tgctgaaggt gttctgaatg tgatagacac
    13021 cgttggctgc atatgccagc gtgagggtgt cagcatgcat gcccatgttg tgcatcaact
    13081 cgggaagctg cattttagcc cagaagttta ccaggtgcag gcccaaaccc acgattacga
    13141 tgatacccag tacgagcatg ttttgagaag cccattccac agtcttgggc ttttccgtaa
    13201 cggcatagcg ttcgctacca cgtgccttac ggttctgcat agtcagccag aaagcgtaga
    13261 tgatgtggat gatgaataag gcagccagac ctaccgtagc caccaatgcg taccagtttg
    13321 ctcccaggaa ctcacaaacc atgttgtagc cattagccga gactaatgca accaggttca
    13381 tcgccatgtg aaatgtcaga aacaggacaa gggcgatacc ggtaacgctc atcaccactt
    13441 tccttcctac agatgaatta cttaaccaca taaatgattg aatttaagtt atttaat
//
