LOCUS       c00093_gnlPro..        10864 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|CMBKEKEM_93.
ACCESSION   c00093_gnlPro..
VERSION     c00093_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-05 15:37:01
            Original ID  :: gnl|Prokka|CMBKEKEM_93
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 10864
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..10864
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[7114:10863]"
                     /cutoff="10000"
                     /detection_rule="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /neighbourhood="10000"
                     /product="succinate2propionate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      7115..10863
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /neighbourhood="10000"
                     /product="succinate2propionate"
                     /protocluster_number="1"
     cand_cluster    1..10864
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /kind="single"
                     /product="succinate2propionate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..10864
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="succinate2propionate"
                     /region_number="1"
                     /rules="(minimum(4, [AcetylCoA_hyd_C, AcetylCoA_hydro,
                     B12-binding, Biotin_lipoyl, Glyoxalase_4, HMGL-like,
                     MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma, PYC_OADA]) and
                     minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /tool="gutsmash"
     CDS             3..680
                     /locus_tag="ctg93_1"
                     /transl_table=11
                     /translation="SIKRAGISIPVLAQTVVDAGDVIEVVGTRQEVEAAAKRLGYIDRP
                     TNQTDMIFVGLGILVGGLFGALSVHIGGIPISLSTSGGALIAGLFFGWLRSKHPTFGRI
                     PEPSQWVLNNVGLNMFIAVVGISAGPSFVQGFHDVGISLFLVGAAATALPLIIGLLLAR
                     YVFKFHPALALGVCAGARTTTAALGAVQDAVESETPALGYTVTYAVGNTLLIIWGVVIV
                     LLL"
     CDS             957..2591
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_1_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GlcNAc_2-epim"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg93_2"
                     /sec_met_domain="Aminotran_1_2 (E-value: 9.8e-23, bitscore:
                     70.2, seeds: 48, tool: rule-based-clusters)"
                     /sec_met_domain="GlcNAc_2-epim (E-value: 0.00011, bitscore:
                     10.9, seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDTKLLEKKMESISPFELKNRLIDMADESLKKTARTMLNAGRGNP
                     NWIATAPREAFFLLGSFGLEECRRIMDLPEGIAGIPEKKGIASHFEAFLKKNNNVSGAK
                     LLEQTYNYLLMQHAADPDSLVHEWAESIVGDQYPVPDRILHFTEILVQDYLSQEMCDNR
                     PPRGAYDLFATEGGTAAMCYIFDSLQENFLLNKGDGIVLMVPAFTPYIEIPQLSRYQFR
                     VTKIHANRMNSEGMHLWQYSDEDIDRLKSPKIKALFVTNPSNPPSYTLSPDTMARIVSI
                     VRNDNPNLMIITDDVYGTFSPHFRSFMAEIPYNTLCVYSFSKYFGATGWRNAVIALHEF
                     NLFDKLIAKLPKEKREILHHRYSTLTLEPERLKFIDRMVADSRQVALNHTAGLSLPQQM
                     QMGLFAAFALLDKENKYKQKMQEIIHRRLHALWENTGFTLTEDPLRVGYYTEIDMLVWA
                     KKFYGDDFVEYLKRTYSPLNVVFRLAKETSLVLLNGGGFDGPEWSVRASLANLDEKDYA
                     TIGRGIKKILEEYAKEFFKNGKAKGKN"
     CDS             complement(2625..3938)
                     /locus_tag="ctg93_3"
                     /transl_table=11
                     /translation="VRIKFFFFILVLFLLGLGGMLVYLLSGKPLLYLYVLEGLIGFILI
                     YLIVFYNKIVKPMNTIGSGMELLREQDFSSRLSRVGQYEADRIVNIFNRMMEQLKNERL
                     RMREQNHFLDLLIQASPMGVIILTMDDEVSQLNPMAVKMLGVRMEEAMAKRLDQMDSPL
                     AAELSSIPKDETAVVRLNDANIYKCTHSSFIDRGFKHPFFLIERMTEEVMRAEKRAYEK
                     VIRMIAHEVNNTTAGITSTLDTVEQALSTEDDMEDICDVMRVCTERCFSMSRFITRFAD
                     VVKIPEPTLVPVQLNELVSMCKRFMEGMCNDRNIELRLECDPEVGMVRMDASLFEQVLV
                     NIIKNAAESIEGDAGENGQQGEIIVRTTAPASVEVVDNGPGISKETEAKLFSPFFSTKP
                     NGQGIGLVFIREVLSRHGCTFSLRTYNDGLTRFRILFN"
     CDS             complement(3929..5290)
                     /locus_tag="ctg93_4"
                     /transl_table=11
                     /translation="MILIIDDDSAVRSSLSFMLKRAGYEVKTAPGPREAMDIVRAEAPA
                     LILMDMNFTLSTTGEEGLTLLKQVKVFRPDVPVILMTAWGSIQLAVQGMQAGAFDFITK
                     PWNNAALLQRIETALELTAAPKEVPEEQTTALNRSYIIGKSKGLMEVLNTVARIARTNA
                     SVLITGESGTGKELIAEAIHINSQRVKQPFVKVNLGGISQSLFESEMFGHKKGAFTDAS
                     ADRIGRFEMANKGTIFLDEIGDLDPSCQVKLLRVLQDQTFEVLGDSRPRKVDVRVVSAT
                     NADLRKMVSERTFREDLFYRINLITVKLPSLRERREDIPLLARHFADRQAEVNGLPRTD
                     FSADALNFLSRLPYPGNIRELKNLVERTILVSGKPVLDATDFDAQYLRHDEPAKVAEGT
                     SFAGMTLDEIERQTILQALEQHKGNLSQVAVSLGISRAALYRRLEKYNIQVPCA"
     CDS             complement(5434..6921)
                     /locus_tag="ctg93_5"
                     /transl_table=11
                     /translation="MKKNILLAVCFLMPLATMAQNDTLGHERNITLSEAIVLARTQSVD
                     AAVALNELKTAYWEYRTFRADLLPEVNFTGTLPNYNKSYSTYQNSDGSYSFVRNNTLGL
                     SGQLSVDQNIWFTGGKLSLTSSLDYLKQLGSGGAKQFMSVPVSLELTQPVFGVNTLKWN
                     RRIEPVRYAEAKAEFISATEEVTMKTITYFFELLLAKESLATAMQNKTNADRLYEVAIA
                     KRKMGQISENDLLQLKLNSLQGKADVTEAESNLNAKMFQLRSFLGVSEQESLNPVLPAT
                     VPDIKMEYDRVLNKALERNSFAQNIRRRQLEADYEVATARGNLRSIDLFASVGYTGQNH
                     EFSSAYRDLLDNQIVQVGVKIPILDWGKRRGKVRVAKSNREVVLSRIRQEQMDFNQDIF
                     LLVANFNNQAQQLDIAEEADVIAEKRYKTSVETFMIGKISTLDLNDAQNSKDEARQKHI
                     SELYYYWYYFYQLRSLTLWDFERDTELEADFEEVVRG"
     CDS             7115..7627
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: Glyoxalase_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg93_6"
                     /sec_met_domain="Glyoxalase_4 (E-value: 3.2e-26, bitscore:
                     81.2, seeds: 51, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKNFFIKEEFSFFVLLYTFIKKDTILTLIYIVMKISHIEHLGIAV
                     KSIEEALPYYENVLGLKCYNIETVEDQKVRTAFLKVGDVKIELLEPTSPESTIAKFIEK
                     NNGNGGMHHLAFAVEDGVAGALAEVEEKGIRLIDKAPRKGAEGLNIAFLHPKSTLGVLT
                     ELCEKPE"
     CDS             7686..9239
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: CT_Btheta"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg93_7"
                     /sec_met_domain="CT_Btheta (E-value: 1e-291, bitscore:
                     956.9, seeds: 72, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSNQLEKIKELIDRRAAARLGGGEKAIAKQHEKGKYTARERIAML
                     LDEGSFEEMDMFVEHRCTNFGMEKKHYPGDGVVTGCGTIEGRLVYIFAQDFTVSAGSLS
                     ETMSLKICKIMDQAMKMGAPCIGINDSGGARIQEGINALAGYAEIFQRNILASGVIPQI
                     SGIFGPCAGGAVYSPALTDFTLMMEGTSYMFLTGPKVVKTVTGEDVSQENLGGASVHST
                     KSGVTHFTAQTEEEGLALIRKLLSYIPQNNLEEAPYVDCTDPIDRLEDSLNDIIPDNPN
                     KPYDMYEVIGAIIDNGEFLEIQKDYSKNIIIGFARFNGQSVGIVANQPKYLAGVLDSNA
                     SRKGARFVRFCDAFNIPIVSLVDVPGFLPGTGQEYNGVILHGAKLLYAYGEATVPKVTI
                     TLRKSYGGSHIVMSCKQLRGDMNYAWPTAEIAVMGGAGAVEVLYAREAKEQENPAQFLA
                     EKEAEYTKLFANPYNAAKYGYIDDVIEPRNTRFRIIRALQQLQTKKLTNPAKKHGNIPL
                     "
     CDS             9271..10203
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: OAD_gamma"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg93_8"
                     /sec_met_domain="OAD_gamma (E-value: 8.4e-18, bitscore:
                     54.3, seeds: 234, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNKTKIGIFLSLMLVLGFCSSCKEQKSNNKLLLNEVLVNNESNYQ
                     DDYGVHSAWIEIFNRSYGSADLAGCYLKFSSQPGDTASYFIPKGDVLTLIKPRQHALFW
                     ADGEPRRGTFHTNFKLDATNANWIGLYDSGKKLLDQVIVPAGTLKANQSYARVSDAADQ
                     WEVKGGSEDKYVTPSTNNKTIDSNAKMEKFEEHDSVGIGMAISAMSVVFCGLILLYISF
                     KIIGKISVNLSKRNAMKAKGITDKQEAKEKQLGQAPGEVFAAISMAMHEFQSDVHDVED
                     TILTITRVKRSYSPWSSKIYTLRETPHKK"
     CDS             10227..10661
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: Biotin_lipoyl"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1024:Biotin-requiring enzyme (Score: 67.3; E-value:
                     2.7e-21)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg93_9"
                     /sec_met_domain="Biotin_lipoyl (E-value: 4.4e-22, bitscore:
                     67.3, seeds: 40, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKEYKYKINGNVYKVAIGDIEDNIAHVEVNGTPYKVEMEKAPKVV
                     VKPVARPAATSAPAAPATPVVKPAAASTGKSGVKSPLPGVILDIKVNVGDTVKKGQVII
                     ILEAMKMENNINADKDGKITAINVNKGDSVLEGTDLVIIE"
     CDS             10663..10863
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: OAD_beta"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg93_10"
                     /sec_met_domain="OAD_beta (E-value: 5.6e-16, bitscore:
                     47.8, seeds: 229, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGEFITFLGNNLADFWTYTGFANATVGHVVMLLVGLFFIYLAVAK
                     EFEPMLLIPIGFGMLIGNIPFN"
ORIGIN
        1 ggagcatcaa gcgcgccgga atatccattc ccgtgctggc acaaacggta gtagatgccg
       61 gcgacgtcat cgaagtggta ggtaccaggc aggaagtgga agcagcagcc aaacgtctgg
      121 ggtatataga ccgccctacc aaccagacgg atatgatatt cgtaggcctt ggtatccttg
      181 tcggaggttt gttcggagca ctttccgtcc atatcggcgg catccccatc agcttgagca
      241 caagcggcgg cgcattgatt gcgggcttgt tcttcggctg gctccgcagt aagcacccca
      301 ccttcgggcg cattcccgaa ccttcgcaat gggtgttgaa caatgtcggt ctgaacatgt
      361 tcattgcggt agtgggcatt tcggcaggtc ccagtttcgt gcagggcttc cacgacgtag
      421 gtatcagcct gtttctggtg ggagcagccg ccaccgccct gccgctgatt atcggcttgc
      481 tgctggcaag gtatgttttc aagttccatc cggcactggc tttgggcgtc tgcgcggggg
      541 cacgtaccac tacggccgct ttaggcgcag tgcaggatgc cgttgagagc gagacacctg
      601 ctctgggata caccgtgacc tatgccgtgg gcaatacctt attaataata tggggtgtag
      661 tcatcgtttt gctactataa gacgattctg tgccgatact tactaatccg aaccattcaa
      721 agaattattg ccggaaatgc aagcgactat atacccattc actaatagct attcgtccga
      781 cagctgtcgg acgataattc aacagttgtc ggacgatgat tcaacaactg tcggacgaaa
      841 aggaaacata tatcggacga ttaatttcaa gcaaggaaag aaatagtata ccgcatgaac
      901 agagattatt cgccgaatga ctgaaaacaa taaataacga acctaaactt gagcttatgg
      961 atacaaaact tttagaaaag aaaatggaat ctatcagtcc tttcgaactg aagaaccgcc
     1021 tgatagacat ggcagacgag agtctgaaga aaaccgcccg taccatgctg aacgcagggc
     1081 gcggcaaccc caactggatt gcaaccgctc cacgcgaagc ctttttccta ttgggaagct
     1141 tcggcttgga agagtgccgt cgcatcatgg atttgcccga gggcattgca ggcatccccg
     1201 aaaaaaaagg cattgcctcc cacttcgaag ccttcctgaa aaagaacaat aacgtatcgg
     1261 gcgccaaatt gctggaacaa acctacaact acctgctgat gcagcatgcc gccgaccccg
     1321 acagccttgt acacgaatgg gccgaaagca ttgtaggcga tcagtatccc gtgcccgacc
     1381 gcatccttca ttttacggaa atccttgtgc aagattacct ttcgcaagag atgtgcgaca
     1441 accgtcctcc ccggggtgcc tatgacctgt ttgccaccga aggtggaaca gccgccatgt
     1501 gctacatctt cgactccctg caggaaaact tcctgctgaa caaaggggac ggcatcgtcc
     1561 tcatggttcc tgcctttacc ccctatattg aaatcccaca actcagccgc taccagtttc
     1621 gagtgaccaa aatacatgcc aaccgcatga atagcgaagg gatgcacctc tggcagtaca
     1681 gcgacgaaga catagaccgc ttgaaaagcc ctaaaatcaa ggccctcttt gtcaccaatc
     1741 ccagtaatcc gcccagctac acactcagtc cggatacaat ggcgcgcatc gtgagcatcg
     1801 tcagaaatga caaccctaat ctgatgatta ttacagacga cgtatacggt acattcagtc
     1861 cgcacttccg ttcgttcatg gcagaaattc cctacaatac gctttgcgtc tattcattct
     1921 ccaaatactt cggtgccacc ggatggcgca atgcggtcat tgccctgcac gaattcaacc
     1981 tgttcgacaa gctgatagcc aaactgccga aagagaaacg ggagattctg caccaccgct
     2041 actccaccct cactctggaa cctgaaagac tgaagtttat cgaccgtatg gttgccgaca
     2101 gccgtcaggt ggcactgaac cataccgccg gactgtcatt gccacaacag atgcagatgg
     2161 gccttttcgc cgcctttgcc ctgctggaca aggaaaacaa atacaagcaa aagatgcagg
     2221 agattatcca ccgccgattg catgcccttt gggagaatac cggtttcacg ctgacggaag
     2281 acccgttgcg cgtaggttat tatacagaaa tcgacatgct ggtttgggca aagaagttct
     2341 atggggacga ctttgtagaa tatctgaaac gcacctacag cccgctgaac gtagtcttcc
     2401 gccttgccaa agaaacctct ctggtgctgc tgaacggcgg tggttttgac ggccccgaat
     2461 ggagcgtgcg cgcctcactc gccaatctgg acgagaaaga ctatgcgacc atcggccgag
     2521 gcattaaaaa gatactggag gagtatgcaa aagaattctt taaaaatgga aaggcgaaag
     2581 gtaaaaattg aaaattgaaa ggtgaaaggt aaaactttca aatttcaatt aaatagtata
     2641 cggaagcggg tcaatccatc gttgtaggta cgtagggaga acgtgcaacc atgacggctc
     2701 aaaacttccc ggataaacac caggccaatt ccctgcccgt tcggcttggt ggaaaagaag
     2761 ggactgaaga gtttagcttc ggtctcttta cttatccccg gaccattgtc aacgacttcg
     2821 acagaagcgg gggcagtggt ccttactatt atctcacctt gctgtccgtt ttctccggcg
     2881 tccccctcta tactttcggc ggcattcttg atgatattca caagcacctg ctcaaaaaga
     2941 gaagcatcca tacgcaccat tcccacctcc gggtcgcatt ccagacgtag ctctatattg
     3001 cggtcattgc acattccttc cataaaacgc ttgcacatgg acaccaactc attcagttgg
     3061 acgggcacca gggtaggttc aggtatcttt accacatctg caaaacgggt aatgaaacgg
     3121 ctcatcgaga aacaacgctc cgtacagacg cgcatcacgt cgcagatgtc ctccatatca
     3181 tcttctgtag aaagtgcctg ctccactgta tcgagtgtgg aagtgatgcc cgcagtggta
     3241 ttgttcactt catgagctat catgcggatt accttttcat aggcacgctt ctcggcacgc
     3301 atcacttctt ctgtcatacg ctctatcaag aaaaaaggat gtttgaaccc tctgtcaata
     3361 aaagaagaat gggtgcattt ataaatattc gcgtcattga gacggaccac tgccgtctcg
     3421 tctttgggaa tggacgaaag ttcggcagcc aacggggagt ccatctggtc cagccgcttt
     3481 gccatcgcct cctccatacg gacaccgagc atctttaccg ccatcggatt cagttgcgac
     3541 acttcatcgt ccattgtcag gataataacc cccattggag atgcctgaat cagcaaatcc
     3601 aagaagtgat tctgctcgcg catgcgcaac cgttcattct tgagctgctc catcattcgg
     3661 ttaaagatat tcacaatgcg gtctgcttcg tactgcccta cccggctgag acgactactg
     3721 aaatcctgct cgcgcagcaa ctccataccg ctgcctatgg tgttcatcgg cttcactatc
     3781 ttattataga atactatcag atagataagg ataaacccga tgagcccctc caatacgtac
     3841 agatacaaaa gcggcttccc actcagcaaa tataccaaca ttccacccag accgagcaga
     3901 aaaaggacaa gtatgaagaa aaagaatttt atgcgcacgg gacttgaata ttatattttt
     3961 ccaaacgtct gtaaagcgca gcgcggctga tgcctaatga cactgccacc tgactgagat
     4021 tccctttatg ctgttccaac gcctgcaaga tagtctgccg ctctatttca tccaaggtca
     4081 tacctgcaaa agaagtacct tcggcaactt tggccggttc gtcgtgacgc agatattggg
     4141 catcgaaatc cgtggcatcc agcaccggct tgccgctgac cagaatggta cgctccacta
     4201 gattcttcaa ctcacgaatg ttgcccggat aaggcaggcg ggaaaggaaa ttcagagcgt
     4261 cggccgagaa atccgtacgc ggcaagccgt tcacctctgc ctgacggtcg gcaaagtgac
     4321 gtgccagcaa aggaatatct tcacggcgct cccgcaagga gggcagtttt acggtaatca
     4381 ggttgatacg gtaaaaaagg tcttcacgga aagtacgttc ggacaccatc ttgcggaggt
     4441 ctgcattagt ggcggacaca acgcgtacat cgactttgcg gggacggcta tcgcccagca
     4501 cttcgaatgt ctggtcttga agcacgcgca gcagtttcac ctggcaggaa gggtcgaggt
     4561 caccaatctc gtcgaggaag atagtacctt tatttgccat ttcaaaacgc cctatacggt
     4621 cggcgctggc atcggtaaac gcccctttct tatggccgaa catctcgctc tcgaacaagc
     4681 tctgcgagat gccaccaagg ttcaccttga caaagggctg cttcacgcgt tggctgttga
     4741 tatggatggc ttcggcaatc agctccttgc ccgttccgct ttcgcccgta atcagcaccg
     4801 aagcattggt acgggctatg cgggccactg tgttcaacac ttccatcaac cctttggact
     4861 tacctataat atagctgcga ttcaatgcgg tagtctgttc ttccggcacc tctttcgggg
     4921 cggccgtaag ctcaagggcc gtctcgatgc gctgcaaaag agcagcattg ttccaaggct
     4981 tagttatgaa atcgaatgcg ccggcctgca taccctgcac ggcaagctgg atacttcccc
     5041 atgccgtcat caaaataacg ggcacatcgg gacggaacac ctttacctgc ttcaataagg
     5101 taagtccctc ttctccggta gtggaaagag tgaagttcat atccatcaaa atcaaagcgg
     5161 gagcttcggc cctaactata tccatagctt cgcgaggacc cggagccgtt ttcacctcat
     5221 atccggcacg cttcagcata aagctgaggg aagagcgcac agcactatcg tcgtctatta
     5281 tcagtatcat aaaaattgta gtttgtttcc cgcaaaaata agtaaaaaag cagagttatg
     5341 aatgataagt tataagttat ttacctataa tatcgcatat acggtacttt taccggcaaa
     5401 taattcataa cttatcactt gcaacccgtc gacttatcct cttaccacct cttcaaaatc
     5461 agcttccaat tccgtatcgc gttcaaaatc ccaaagggtc aagctgcgga gctgatagaa
     5521 gtaataccaa tagtagtaca gctctgaaat atgcttttga cgggcttcgt ctttagagtt
     5581 ctgtgcatcg ttcaggtcca gggtgctgat tttacctatc ataaaggtct ctacactagt
     5641 cttgtaacgc ttctcagcaa tgacatccgc ctcttcggct atgtccagct gttgcgcctg
     5701 gttgttgaag ttagccacca gcaaaaagat gtcctggtta aagtccatct gttcctgacg
     5761 gattctggac aagaccactt cacggttgct ctttgccacc cttaccttgc cgcggcgctt
     5821 gccccagtca aggataggaa tcttgacgcc tacctgcaca atctgattgt caagcaagtc
     5881 ccggtaggct gaagagaatt catggttctg ccccgtatag cccacactgg caaagaggtc
     5941 gatgctgcgc aagtttccgc gtgccgttgc cacttcataa tcagcttcga gctggcggcg
     6001 gcgaatgttc tgtgcaaagg agttgcgttc cagtgccttg ttcagcacac ggtcatactc
     6061 catctttata tcgggaacag tggcgggcaa caccggattc aggctttcct gctcggacac
     6121 cccgaggaaa gaacggagct ggaacatttt tgcattcagg ttgctctctg cctcagtcac
     6181 gtcggccttg ccctgcaatg aattcagttt aagctgcaac aaatcattct cggatatctg
     6241 tcccatttta cgtttggcta tggccacttc ataaaggcgg tcggcattcg tcttgttctg
     6301 catggcggta gcgagcgatt ctttggccag cagcaactca aagaaataag tgatggtttt
     6361 catcgtcacc tcttccgtag ctgaaatgaa ctcggccttt gcctcggcat agcgtacggg
     6421 ctctatacgg cggttccact tcaaggtatt cactccgaag accggttgcg tcaactccag
     6481 actcacgggg actgacatga actgcttcgc tcctccggaa cccagttgtt tgagataatc
     6541 cagcgaagaa gtcagtgaca gcttaccccc cgtaaaccaa atgttctggt ctaccgaaag
     6601 ctgtccggac agccccagtg tattgttgcg aacaaagcta taggagccgt cggaattctg
     6661 gtaggtactg taggacttgt tatagttggg tagtgtaccg gtgaaattca cttccggcaa
     6721 caagtccgca cggaatgtac ggtattccca atacgcggtt ttcaattcat tcaatgccac
     6781 agcagcatcc acagactgcg tacgggccag tacaatggcc tccgacagcg taatattgcg
     6841 ttcatgtccc aaagtatcat tctgcgccat ggttgccaac ggcatcaaaa aacaaactgc
     6901 aagtaaaata ttctttttca tgttcaatct ttaaaattgt cgcaaacaga aaagcaaaga
     6961 gtgtgccaag tggccggaaa ggtttcatag aggggtaagt gttcattttc ggacagtggg
     7021 gatgtccgtt agcggacgat atcaagaaaa caaccggtct ctatctaaag tctgaaaaaa
     7081 tccttctaaa gttcaattaa ccattaatta attgatgaaa aatttcttta ttaaggaaga
     7141 attctctttc tttgtgctgc tttatacctt tattaaaaag gatacaatac taacattaat
     7201 ttatatagtt atgaagattt cacacattga gcatctgggc attgccgtta agagcattga
     7261 agaagccctt ccgtactacg aaaacgtttt aggtttgaaa tgctacaaca tcgaaaccgt
     7321 ggaagatcag aaagttagaa ccgctttcct gaaagtgggc gatgtaaaga tcgaattgtt
     7381 ggaacctact tctcccgaaa gcacaattgc caagttcatc gaaaagaaca acggtaacgg
     7441 tggcatgcat catctcgcat tcgccgttga agacggagtg gccggtgcgc ttgccgaagt
     7501 cgaagaaaaa ggtatccgcc ttatagacaa agctccccgc aaaggtgcag aaggtctgaa
     7561 cattgcattc ctgcatccga agtcaactct cggtgtcctg accgagcttt gcgagaaacc
     7621 ggaataagca agactgtaaa atcatcaaat cataaattgt ataaacactt aaagaatata
     7681 aattcatgag taatcaactt gaaaagatta aagagcttat agaccgccgc gctgcagcac
     7741 gtctcggtgg tggtgaaaaa gcgattgcaa agcaacacga gaagggtaaa tatacagctc
     7801 gcgagcgcat agccatgctt ctcgacgaag gcagtttcga agaaatggac atgttcgtag
     7861 aacatagatg caccaacttc ggcatggaaa agaaacacta ccccggtgac ggtgtagtaa
     7921 ccggttgcgg tacaatcgaa ggccgtctgg tttatatctt cgcacaggac ttcacagttt
     7981 ctgccggttc actgtccgaa accatgtctc tgaaaatctg taagattatg gaccaagcca
     8041 tgaaaatggg tgctccgtgt atcggtatca acgactcggg cggtgcacgt attcaggaag
     8101 gtattaatgc cttggctggc tacgctgaaa tcttccaacg taacatactt gcttcgggtg
     8161 tcattccgca gatttccggt attttcggtc cttgtgccgg tggcgccgtt tactctcctg
     8221 ccttgacaga ctttactttg atgatggaag gtacatccta catgttcctt accggtccga
     8281 aggtagtaaa gactgtaacc ggagaagacg taagccagga aaacctgggt ggcgcgagcg
     8341 ttcactccac caaatctggt gttactcatt ttactgcaca gacagaagaa gaaggtttgg
     8401 cccttatccg caaactgttg agctacattc cccagaacaa tctggaagaa gctccctatg
     8461 tagactgtac agaccctatt gaccgtctgg aagattccct gaacgatatc attcctgata
     8521 acccgaacaa accgtacgat atgtacgagg taattggcgc tatcatagat aatggtgagt
     8581 tcctcgaaat ccaaaaagat tattcaaaga atatcattat tggtttcgca cgtttcaacg
     8641 gacagtccgt aggtattgtt gccaaccagc cgaagtatct ggcaggtgtg ctcgacagca
     8701 acgcatcccg caagggcgca cgcttcgtcc gtttctgcga cgccttcaat attcctatcg
     8761 tatcattggt agacgtaccg ggattccttc cgggaaccgg ccaggagtac aacggcgtca
     8821 tcctgcacgg tgccaaactg ctgtatgcat acggtgaagc tactgtaccc aaggttacca
     8881 tcacactgcg taaatcctac ggtggttcgc acatcgtgat gagctgtaag cagctgcgtg
     8941 gcgacatgaa ttatgcttgg cctactgctg aaatcgctgt aatgggtggt gcaggtgctg
     9001 tagaagtatt atatgcccgc gaagccaaag agcaggaaaa tccggctcaa ttcctggctg
     9061 aaaaagaggc tgaatacacc aagttgtttg ccaatcctta taatgcagct aaatatggct
     9121 acattgatga tgttatcgaa ccgcgtaaca cacgtttccg catcattcgt gccctgcaac
     9181 agttgcaaac caagaaattg actaacccgg ctaagaagca tggtaatatt cccttgtaat
     9241 caagcttttc acactaaaac aagaacgatt atgaataaaa ctaaaatcgg aatattcctt
     9301 tcattgatgc tggtgttggg cttttgctct tcttgcaaag aacagaaatc gaacaacaaa
     9361 ctgctgctga atgaagtgct ggtcaacaac gaaagcaact atcaggatga ctacggtgtg
     9421 cacagcgcat ggattgaaat attcaacaga tcatacggca gcgccgacct tgcaggttgc
     9481 tatctgaaat tcagcagcca gccgggtgat actgccagtt atttcattcc caaaggtgac
     9541 gttctgacac tcataaaacc acgtcagcat gcacttttct gggctgatgg agaaccaaga
     9601 cgcggtacat ttcatacgaa cttcaaactg gatgccacaa atgccaactg gattgggttg
     9661 tatgattccg gcaagaaatt gcttgatcaa gtcatagtgc ctgccggtac tttaaaagcc
     9721 aaccaatcct atgcccgtgt cagtgatgca gccgaccaat gggaagtaaa gggtggaagc
     9781 gaagataaat atgtcactcc gagtaccaac aacaagacta tcgacagcaa tgccaaaatg
     9841 gaaaaattcg aagagcatga cagcgtaggt atcggtatgg ctatttctgc catgagcgtt
     9901 gtattctgcg ggctgatatt actctacatc tccttcaaga ttataggtaa aatatcagtt
     9961 aacctcagca aacgcaatgc catgaaagct aaaggtatta ctgataaaca agaagcaaaa
    10021 gagaaacaac tggggcaggc tccgggagaa gtttttgctg ccatttcaat ggccatgcac
    10081 gaattccaaa gcgatgtaca cgatgtggaa gacacgatac ttaccattac ccgtgtaaaa
    10141 cgcagttact caccgtggag ttcaaagatt tatacgttgc gtgagactcc tcacaaaaag
    10201 taagtcaccc ataataaaat aaaacgatga aagaatataa atataaaatt aacggtaacg
    10261 tatataaagt tgccattgga gatattgaag acaacatcgc tcacgtagaa gtgaacggta
    10321 ctccctacaa agttgaaatg gaaaaagcac cgaaggtagt cgttaaaccg gtagcacgtc
    10381 cggcagccac atccgctcct gctgctcctg ctactccggt agtaaaaccg gccgctgctt
    10441 ctaccggcaa gtcaggtgta aaatctccgc ttcccggtgt aatcctcgat atcaaagtaa
    10501 atgtcggcga tacagtaaag aagggacaag ttatcatcat tctggaagcc atgaagatgg
    10561 aaaacaatat caatgctgat aaagacggta agattacagc catcaatgta aacaaagggg
    10621 actctgttct cgaaggtact gaccttgtaa ttattgaata atatgggaga atttatcaca
    10681 tttttaggaa acaaccttgc cgacttctgg acttatacag gttttgccaa tgcaacggta
    10741 ggacatgtgg taatgcttct ggtaggtttg tttttcatat acttggctgt agccaaggaa
    10801 tttgagccga tgctattaat tcctatcggt ttcggtatgc tgattggtaa tatacctttc
    10861 aata
//
