LOCUS       gnlProkkaELELMNCO_32   10828 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|ELELMNCO_32.
ACCESSION   gnlProkkaELELMNCO_32
VERSION     gnlProkkaELELMNCO_32
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-12-02 03:10:57
            Original ID  :: gnl|Prokka|ELELMNCO_32
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 10828
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..10828
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="True"
                     /core_location="[2286:5828]"
                     /cutoff="20000"
                     /detection_rule="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /neighbourhood="5000"
                     /product="phosphonate"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      2287..5828
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /neighbourhood="5000"
                     /product="phosphonate"
                     /protocluster_number="1"
     cand_cluster    1..10828
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /kind="single"
                     /product="phosphonate"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..10828
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="phosphonate"
                     /region_number="1"
                     /rules="(phosphonates and minimum(1, [2-Hacid_dh_C, Aldedh,
                     Aminotran_1_2, Aminotran_5, AurF, CTP_transf_like, DUF4992,
                     Fe-ADH, HMGL-like, Metallophos_2, NTP_transf_3,
                     NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C, TPP_enzyme_N,
                     phosphonates]) and not (phosphonatesHydrolase or
                     phosphonatesMeIsocitrateLyase))"
                     /tool="antismash"
     CDS             2..298
                     /locus_tag="ctg32_1"
                     /transl_table=11
                     /translation="MHSLQREELATGNLLQGGSGKYIIHSHHGTVYRLAVTDITNVKFY
                     FGILQVMTHVILLFLVTTKNTNLLDIRIKETTQYSVTKTAGTSGYKEDFVFKY"
     CDS             complement(316..1062)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_1"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg32_2"
                     /sec_met_domain="Glycos_transf_1 (E-value: 7.8e-13,
                     bitscore: 39.9, seeds: 63, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSWKELMIEKARNLYLYYYFKRGVTAFWTENPYISEKVKHLFPTI
                     KAYTVSNYYNQVFDDENTQIEHALPSFDGCTLLSINAPYPHKNLAIAIEVARYLKKHYS
                     EFSFRFVFTVTENDLPPIPSYLREHFCLIDKVSVAECPSLYRQADIMFQPTLLECFTAT
                     YVEAMRMQVPILTTDLPFAHGLCGNAAVYYSPLDAEDCAKSIYKMAVDTSFQDYLVGEG
                     IKQLKSFDNYNRRAEKLIDLISNLDD"
     CDS             complement(1490..1579)
                     /locus_tag="ctg32_3"
                     /transl_table=11
                     /translation="MKTNFNIRSIIVINKIIINFFFRQYRWYL"
     CDS             complement(1586..2302)
                     /locus_tag="ctg32_4"
                     /transl_table=11
                     /translation="MSRGISEKEQRWLLVLSQVIEVLDKNNLLYFIDTGTLLGAVRDKM
                     FIPWDNDIDLAVIGGDTSTTNLLKVSKLLYALGFYVTLTKKEIAICSRDGVNLGIKLYK
                     KQASHYEACMGKVYRHRLFYSINLYLSGEVLYKKGFSFKYKAISLFVKFSQVFKLKLSC
                     IWQMKLLFWAKYDEKTVIIPFEFVDAIIDYNFYNIIVKVPNKPERYLAYRYGENWKVPK
                     QDYDYMIDDKSIINID"
     CDS             complement(2287..3381)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: Fe-ADH"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg32_5"
                     /sec_met_domain="Fe-ADH (E-value: 5.4e-76, bitscore: 247.2,
                     seeds: 218, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEQRFFLGESSIKELIPILQEYTPDHIFLVRGKKSYEKCGAQAVL
                     ESVFVKLACGVTEFFDFEANPKIEDMEKGLSLLKEYPTNMIIAIGGGSVLDMAKLLRFF
                     YSYSGNPTGGEFEKKRQLIPLITLPTTAGTGSEATHFSVLYKDKVKYSVEHDAILPDVA
                     IVYPKFTYGNSKYLTSCTGFDALAQAIEAYWNVNATEESDKYAAKAIKLLWPNLPLVVN
                     SPTAEARNKVSEGSYWAGRAINITKTTAPHAFSYSFTTDYGYPHGHAVALTFPFFMRYN
                     IGNSDILLNPNINPYLYKIKMQKMLQWLNMECVDVAIAMKEYIRNLGLDIDISQIDISK
                     IVSSVNIQRLINNPYKVEAICLEE"
     CDS             complement(3389..4519)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: TPP_enzyme_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: TPP_enzyme_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1055:pyruvate oxidase/decarboxylase (Score: 69;
                     E-value: 6e-21)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg32_6"
                     /sec_met_domain="TPP_enzyme_N (E-value: 6.5e-17, bitscore:
                     53.2, seeds: 75, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 1.1e-20, bitscore:
                     65.5, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MISPNIFVDSLGAMQMDFFTGVPDSLLKNICAYLTDHLASEHNII
                     AANEGAAIGLATGYYLATRKIPVVYMQNSGLGNAVNPLMSLTDKEVYNIPLLLLIGWRG
                     EPGVKDEPQHIKQGKVTLPLLEAMGIRYAVLSQDEKKFISQLNVAKSYMDETREPFAFV
                     IQKDTFLEYSSENCEDERLSLKREAAIHFIAASLTEKDIIISTTGMISRELFEYRESTS
                     LEHERDFLTVGSMGHASQIALGIALKKRDCKVYCFDGDGSTLMHMGSLAIVGSLHPENY
                     VHVVFNNGAHDSVGGQPTVALDIDLCKIAQACGYEIVLSVSDNEGLCEALKKIQQIRGP
                     ILLEVKVRKGARKNLGRPANTPIQNKEAFMLFLDNL"
     CDS             complement(4551..5828)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: PEP_mutase"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: CTP_transf_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: phosphonates"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1231:carboxyvinyl-carboxyphosphonate (Score: 202.7;
                     E-value: 1.2e-61)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg32_7"
                     /sec_met_domain="CTP_transf_like (E-value: 1.9e-12,
                     bitscore: 39.1, seeds: 65, tool: rule-based-clusters)"
                     /sec_met_domain="phosphonates (E-value: 2.8e-119, bitscore:
                     388.9, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PEP_mutase (E-value: 9.2e-64, bitscore:
                     206.7, seeds: 69, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSADIIHPGHLNIIHEASKLGHVTVGVLTDSAIASYKRLPYLNFD
                     QRSLIVLNLKGVDEVIPQTTLDYVPNLELIRPDFVVHGDDWKEGIQQETRQRVIDTISK
                     WGGKVIDVPYTKGISSTLLNTRLKEIGTTPEIRLKRLKRLIAAKSIVRICESHSGLTGL
                     IIENTSVEVNGVKREFDGMWSSSLTDSTSKGKPDIEAVDLTTRLHDLNDALECTTKPVI
                     FDGDTGGKIEHFVFTVRTLERLGISAVIIEDKIGLKKNSLFGTDAVQTQDTIEGFCDKI
                     QAGKRAQITDDFMIIARIESFIAGKGLDDALGRALAYIKAGADGIMIHSKDKSGEDIKN
                     FCLALRKIHKSIPIVVVPTTYNHISEDELASWGVNVVIYANHMLRSAYPAMLNTAKSIL
                     ANARSYEANDLCMPIKEILELIPGTK"
     CDS             complement(5818..6948)
                     /locus_tag="ctg32_8"
                     /transl_table=11
                     /translation="MKVTTDNSFYNLVIGNNKMILLLMLACIVTYYYAMKFALVIELYG
                     AGEGRMMRFEAGELFTSNLEVYLYDFLIKPFTQFVMLIVACMLLSKIKRRILLLSVLFL
                     FLYASVGNGRGGLIVFLFYCFIIYYLRRELYYINLLASKRKKWNFGVVSFVCLFVGVGI
                     IVVVISYMTAQRMGFDTFSAEVVKIGFEELKSQAVWYFLGPFRALDYSFRANYESITGF
                     WYGRATMGGIDNLLKLVIHYLGGSYTIAHDEIGHLLQNSKISVGNGIIFNYAYTNIIFH
                     YLDFGYVGVLLFPFLYGFIVRYSIYKFTQKPTLLTLGIMIYLVYISMFNIFSWEFQKPS
                     SIIYVLLLLFFQYVYSHKFVILKLNGKKKGLCRHEC"
     CDS             complement(7194..8126)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg32_9"
                     /sec_met_domain="Glycos_transf_2 (E-value: 2.5e-25,
                     bitscore: 80.8, seeds: 256, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNGSITVSICCLTYNHEKYIRQCLDGLIMQKTEFDFEILVHDDAS
                     SDATQSIINEYVVAYPNLIKPILQIRNQYSQGISPLRQILFPLVKGKYVALCEGDDYWT
                     DPLKLQKQVNAMESDHSLAGCAHQSLVFYENGTPSHMFHHVKKQILKTKDLLDVRLFHT
                     ASFLFKKEVLDYIKDFNSSLYAGDRFLFLACSLKGNILYMPDVMCCYRKNAMGVTSRVS
                     YSLHVLDLKVPEYFHNKDLKFPYYRYLAFVHRAIFSESLDISLKKYIYHFTLFVKYSFS
                     YFPKNLKDIYKALYVSFWWLTKGQKYRIK"
     CDS             complement(8127..9122)
                     /NRPS_PKS="Domain: NAD_binding_4 (91-233). E-value: 3e-07.
                     Score: 21.7. Matches aSDomain:
                     nrpspksdomains_ctg32_10_NAD_binding_4.1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1010:NAD-dependent epimerase/dehydratase (Score:
                     114.5; E-value: 1.1e-34)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg32_10"
                     /transl_table=11
                     /translation="MKKKIIIFGATGNTGSYLLEYALNFFNKEEYEIIASGRRETTFFS
                     KRGIPYYSVDITKEEDFDKLPMENIHAVMLLSAQIPSYMDTYCPIKYLDSIVIGGFNVL
                     EYCRKCHVDRIIYTQTVFDISLYSHDTILKPDMKPNFSYTGDHAIYVISKNTALDLIEH
                     YYQEYGLKKFIFRLPTIYSYSPYPYYFPNGVKTKRPIYQMIENAQKGLPIEIWGDPHYA
                     KDMVHVNDFSQMLCKAVEVEQESGFYNVGTGMPITLEEQIRTIISVFSPKESPSEVIYR
                     PDKVCGGGYIMNIENAKKELGYVPQYDCRKLFEDYKSEMEIKRFAELRLK"
     aSDomain        complement(8424..8849)
                     /aSDomain="NAD_binding_4"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg32_10_NAD_binding_4.1"
                     /evalue="3.00E-07"
                     /label="ctg32_10_NAD_binding_4.1"
                     /locus_tag="ctg32_10"
                     /protein_end="233"
                     /protein_start="91"
                     /score="21.7"
                     /tool="antismash"
                     /translation="YLDSIVIGGFNVLEYCRKCHVDRIIYTQTVFDISLYSHDTILKPD
                     MKPNFSYTGDHAIYVISKNTALDLIEHYYQEYGLKKFIFRLPTIYSYSPYPYYFPNGVK
                     TKRPIYQMIENAQKGLPIEIWGDPHYAKDMVHVNDFSQ"
     CDS             complement(9119..10084)
                     /locus_tag="ctg32_11"
                     /transl_table=11
                     /translation="MMSIGGYFELEIREGEHFHQGAIKLSTARQCFEYILKARRYTKVY
                     IPYYTCDVIIEPLMKLNVKYEYYHINSLLDPVFDKKIESSEAFLYTNYFGLKQDTVLYL
                     SRFYPNLIVDNAQAFFAKPIEGVDTFYSARKFFGVPDGAYLYTTALLDIDFPIYNPIDN
                     INYLIGRITDSAEGYYKDFQESEERMSNQEIHRMSVLSDKILSSLDYVSIIERRRFNYH
                     LLYSALTAFNKFDFSISENQNVPLIYPFYTSKAGLRQQLILEHVYVPQYWQNVVNKIDA
                     KCLEYSIANNMIALPIDQRYDEKTMNILIEKISNLNNHLS"
     CDS             complement(10081..10740)
                     /locus_tag="ctg32_12"
                     /transl_table=11
                     /translation="MPYIGYFQLIKAVDKYVVYDDVNYIKGGWVNRNNILVNGEKKMFT
                     ITLKGASAYKHFNEIEIGDDFRKFMKTLELNYSKAPFYHETMELLYRIIMFPNRQLALF
                     LANSFKEILDYLNIQTEILLSSDLPKDCSLKGKDKVLHICKLLSADTYYNAIGGKQIYN
                     KEDFMQNGINLKFVDTIIKRYPQQSKEFVPYLSIIDVLMNNSKEETCMLLDSFSLQ"
ORIGIN
        1 tctgcacagc ctgcaacggg aagaactcgc aactgggaac ctgcttcaag gcggcagcgg
       61 caaatacata atccactccc atcatggcac cgtctacaga ctggcggtca cggacattac
      121 caatgtaaaa ttttactttg ggattttgca ggtgatgacg catgtcatcc tgctttttct
      181 cgtcacgact aaaaatacga atctccttga tatcagaatc aaggaaacga cgcaatacag
      241 cgttaccaaa actgccggta cctccggtta taaggaggac tttgtcttta aatactgaca
      301 taaatataat atgtattaat catccaaatt cgatatcaaa tcgattaatt tttctgctct
      361 ccgattataa ttatcgaagg acttaagttg ttttattcct tctccgacca gataatcttg
      421 aaaggatgtg tctacagcca ttttataaat tgatttggca cagtcttctg catctaacgg
      481 cgaatagtac acagctgcat ttccacataa tccatgagca aatggcaaat ctgtagttaa
      541 aattggcact tgcattcgca tcgcttcgac atatgtggca gtgaaacatt caagtaaagt
      601 tggttgaaac attatatctg cctgacgata taaggaaggg cattctgcta cactaacttt
      661 atcaatcaga cagaaatgct ctcgcaaata agaaggaata ggtggcaagt cattctctgt
      721 caccgtaaaa acgaatcgaa aactaaattc ggaataatgt tttttaagat atcgagcgac
      781 ttcgatagca attgctaaat tcttatgagg ataaggagca tttatggaca gtaaagtaca
      841 accgtcaaaa gacggtaagg catgttctat ttgagtattt tcatcatcga aaacctgatt
      901 ataataattc gatacagtat aggcttttat ggtagggaac aagtgcttta ctttctctga
      961 aatataagga ttctcagtcc aaaaagcagt cacaccacgt ttgaagtaat aatataaata
     1021 aagatttctc gccttttcta tcattagttc cttccaagac atacgttgaa aatagggaga
     1081 atcgttcaaa acgagatggg atctggcaaa tccacataga tgcttacatt tcggcttcca
     1141 tcttgcaggt ccgaatatgg taagaactcc accaatattg tgtctggtta ccaaattatc
     1201 catagcctta tcacgtcccc aaaacaatgt ataccaactg tttcgtatat catgacgcac
     1261 tacagtgaca tttttgtatt ccgataccct atcagcagta tcatccatac atgaggataa
     1321 tactaaaaaa aaatcatgtt ggggaattgt attcaaacaa gaacaaaccg aatcagcgac
     1381 ttgaagccct ccacctttct tgagattgga gcaatttatt agaatgttca tttgttccga
     1441 gaatataata tataagtgcc caattttggt gtataaatga aagtgctatt tataaatacc
     1501 atctatattg tctaaagaaa aagttgatta taattttatt aattacaata atactcctta
     1561 tgttgaaatt tgttttcata tttttttaat caatatttat aatagacttg tcatcaatca
     1621 tataatcata gtcttgtttg ggaaccttcc aattttcacc atatctatat gctagatatc
     1681 tttctggctt atttggcact ttcacaatta tattataaaa attataatca ataattgcat
     1741 ctacaaactc aaaaggaata atcaccgtct tttcatcata cttagcccaa aacaataact
     1801 tcatttgcca aatacaagac aattttaact taaagacttg actaaacttc acaaagagtg
     1861 agatagcttt atacttaaaa gaaaagcctt ttttatacag gacctctcca gagaggtata
     1921 aatttataga ataaaatagt ctatgtctat aaacttttcc catacatgct tcataatgac
     1981 ttgcttgctt tttatataat ttaattccta aatttacccc gtctctagaa cagatagcaa
     2041 tttctttctt tgtcaaagtg acgtaaaagc ctaaagcata taacaatttt gacactttaa
     2101 gcaaattagt agtagatgta tctcctccaa taactgctaa atcaatatca ttatcccaag
     2161 gaataaacat tttatctcta acagctccta aaagagtacc agtatcaata aaatataata
     2221 aattattttt atcaagaact tcaataactt gtgataatac taacaaccat cgttgctcct
     2281 tttcacttat tcctctagac atatcgcttc aactttatat ggattgttta ttaatctttg
     2341 aatattaaca gaagatacga ttttcgatat gtcaatttga gatatgtcaa tatctaatcc
     2401 caagtttctt atatactctt tcatagcgat tgcaacatct acgcattcca tatttaacca
     2461 ctgtaacatt ttttgcattt taatcttata taagtaagga tttatattag gattcaataa
     2521 gatatccgaa tttccaatat tatatctcat aaaaaaggga aatgttaatg ctactgcatg
     2581 tccatgcgga tatccataat cagttgtaaa tgaatacgaa aaagcatgtg gagctgtagt
     2641 cttagttata ttaattgcac gaccagccca ataagagcct tccgaaacct tattcctagc
     2701 ctccgctgta ggagaattta caaccaatgg caaattaggc cataagagtt taattgcttt
     2761 cgccgcatat ttatccgact cttccgtagc attcacattc caataagctt ctatcgcctg
     2821 cgctagagca tcaaagcctg tacaagatgt tagatatttt gaatttccat aagtaaattt
     2881 tggatataca atcgctacat ccggaagaat agcatcatgt tctactgaat attttacttt
     2941 atctttatat aaaacagaaa aatgagttgc ttcactacct gtaccagctg tagtaggaag
     3001 tgttattaat ggaattaatt gtcgcttctt ttcaaactcc ccccccgtag gattaccaga
     3061 ataggaataa aaaaaacgaa gcaattttgc catatctaat acactacctc cacctatagc
     3121 aataatcata tttgtcggat attctttcaa taatgaaagt cctttttcca tatcttcaat
     3181 tttaggattt gcttcaaaat caaagaattc cgtcacgcca caagctaatt taacaaaaac
     3241 agattctaac acagcctgtg caccacattt ctcataagac ttttttcctc ttacaagaaa
     3301 tatatgatca ggagtatatt cttgcaagat aggaatcaat tcttttatag aagactctcc
     3361 taaaaaaaaa cgctgttcca taattactct ataaattatc taagaaaagc atgaatgcct
     3421 ctttattttg tataggagtg ttggctggtc ttcccaaatt cttacgagct ccctttcgaa
     3481 cctttacttc caacaaaata gggccgcgta tttgctgtat ctttttaaga gcttcacata
     3541 aaccttcgtt atcagaaaca gacaatacta tttcataacc acaagcttga gcaattttac
     3601 ataaatcaat atctaaagcg actgttggtt gtccccccac agaatcgtga gcgccattat
     3661 taaagactac gtgtacatag ttttccggat gtaaagaacc gacaattgct aacgaaccca
     3721 tatgcatcaa agtggaacca tctccatcaa agcaataaac tttacagtct ctctttttaa
     3781 gagctattcc caatgctatc tgcgacgcgt gccccataga acctacagtc aaaaaatctc
     3841 tctcatgttc taaagaagta gattcacgat attcaaataa ttcacgtgat atcatacctg
     3901 ttgtcgatat tataatatct ttttctgtta atgaagctgc tatgaaatga atagcagctt
     3961 cgcgtttcaa agacaaccgt tcatcttcac aattttcaga actatactct aagaaagtgt
     4021 ctttctgaat tacaaaagca aaaggctctc ttgtctcatc catgtaagat tttgcaacat
     4081 taagttgaga tataaacttc ttttcatctt gagataaaac agcatatctg atacccattg
     4141 cctcaagtaa tggaagtgtg acttttccct gcttaatatg ttgtggctca tctttcacac
     4201 caggttcacc acgccaacca attagcaata acaatggaat attataaact tctttatccg
     4261 tcaatgacat taaaggattt actgcatttc caagacctga attctgcata taaacaactg
     4321 gaattttcct cgtagccaaa taatatcctg tagccaaacc tatagcagca ccttcattag
     4381 cggcaataat gttatgttca gaagcaaggt gatctgttaa atatgcacat atattcttca
     4441 ataaagaatc gggaactcca gtaaaaaaat ccatctgcat agcgccaaga gagtctacaa
     4501 aaatattagg agaaatcata ataataagaa tttaatttta aagagtctat ttacttagtc
     4561 cctggaatca attccagaat ttctttaata ggcatgcata agtcattggc ttcataagag
     4621 cgtgcattgg caagaatgga cttcgccgta ttaagcatag cgggatatgc acttctaagc
     4681 atatgatttg catatattac aacatttact ccccaagaag ccaattcatc ttctgatata
     4741 tggttataag tagttggaac aaccactatc ggaatggatt tatgtatttt gcgtaaagca
     4801 agacagaagt tctttatatc ctcaccagac ttatctttgc tatggatcat aatcccatcc
     4861 gcacctgctt taatatatgc taatgcacgt cctaaagcat catctaaacc ttttccagca
     4921 ataaaacttt caatacgagc tattatcata aaatcatccg ttatctgagc acgtttaccc
     4981 gcttgaattt tatcacaaaa cccttcaatt gtatcctggg tctgaacagc gtctgttcca
     5041 aaaagcgagt tcttcttcag acctatttta tcctcgataa taacagctga tatccctaaa
     5101 cgttccagcg tgcgaacagt aaatacaaaa tgttctattt taccacctgt atcaccatca
     5161 aaaattactg gtttggtagt acactccaaa gcatcattca aatcatgaag acgagttgtc
     5221 aagtcaacgg cttcaatatc aggcttacct ttagaagtcg aatcagtaag actactggac
     5281 cacatcccat caaattcacg cttaactccg ttgacttcta cactggtatt ttctattatc
     5341 aaacctgtta acccactatg agattcacag atacgaacaa tacttttagc agcaattaag
     5401 cgtttaagtc gcttcaaacg aatttcggga gtggttccta tttccttcaa cctagtattc
     5461 aataaagtgg aagaaatacc tttcgtataa ggaacatcta tcacttttcc accccattta
     5521 gagatagtat caatcacacg ctggcgagtt tcttgttgaa taccctcttt ccagtcatca
     5581 ccatgtacta caaagtcagg cctaatcaat tccaaattcg gaacataatc aagagtagtt
     5641 tgaggtatta cttcatcaac acccttcaaa ttcagaacta tcaatgagcg ctgatcaaaa
     5701 ttcaagtaag gcaaacgctt gtaactggca atagctgaat ctgttaatac accaaccgtt
     5761 acatgcccca attttgaagc ctcatgaatg atattcaaat gacctggatg aataatatca
     5821 gcactcatgc cgacataaac cttttttttt tccatttaat tttaatatta cgaatttatg
     5881 agaataaaca tattgaaaaa atagcaacaa caaaacataa ataattgagg aaggcttctg
     5941 aaattcccac gaaaaaatat tgaacattga tatatagacc aaatatatca taataccaag
     6001 agtcagtaat gttggttttt gagtaaattt ataaatacta tatcgtacga taaagccata
     6061 taaaaatggg aataaaagaa cgccaacgta accaaaatcc aaataatgaa atattatatt
     6121 agtgtatgca taattaaaga tgattccatt cccaactgaa atttttgaat tttgcaaaag
     6181 atgacctatt tcatcatgag caatggtata acttcctcct aaataatgga ttacaagttt
     6241 taataaatta tcaattccac ccattgttgc ccttccatac caaaacccgg ttatcgattc
     6301 ataattagct ctaaatgaat agtctaaagc tctaaatgga cctaaaaaat accatacggc
     6361 ctgacttttt agttcttcaa aacctatttt tacgacctca gcactaaatg tatcaaatcc
     6421 cattctttga gctgtcatat atgaaataac cacaactatt attccaacgc caacgaacaa
     6481 gcatacaaaa gaaactacac caaaattcca ttttttcctt ttgctggcta acaaattgat
     6541 atagtacaat tctcttctta aataataaat gataaaacaa taaaatagaa aaacaatcaa
     6601 tcccccacgc ccattaccaa cagatgcgta taaaaacaga aaaagcaccg atagcaacag
     6661 aattctacgt ttaatcttag aaagtagcat acacgctaca attagcataa caaactgtgt
     6721 aaaaggtttt attagaaaat catatagata tacttctaaa ttactcgtaa aaagttcacc
     6781 agcctcaaat ctcatcatcc gaccttcgcc cgctccatat agttcaataa ctagagcaaa
     6841 cttcattgcg taataataag taacaataca tgccaacata agaagtaata tcatcttatt
     6901 attgccaata accagattat aaaaactatt atctgttgta accttcaatc gtattttttt
     6961 tatttttcca aaacaaagaa atccccaatt aaacgcccaa acattgatca ataataacat
     7021 atatgttttc attgacacag aatatagttc agctggatca aaagtagaaa taacaatagc
     7081 agttccccac cacaataaat atatgaaact tatttttctt gaaaaagaat caattataag
     7141 cctattagat atcaaaatct gaattaagaa tagaataaga aaaattatag caatcatttg
     7201 attctatact tttgtccctt tgtcaaccac cagaaagaaa catataaagc cttatagata
     7261 tctttcagat tcttaggaaa ataagaaaaa gaatatttca caaataaagt aaaatgatat
     7321 atatatttct ttaaggaaat gtcaagtgat tctgaaaata tagctctatg aacaaatgcc
     7381 aaatatctgt aataaggaaa tttcaaatct ttattatgaa aatattcagg aacttttagg
     7441 tctaatacat gtaatgaata agaaactcta gaagtaactc ccattgcatt cttcctataa
     7501 caacacatta catctggcat atataaaata tttcctttca acgaacaagc caaaaacaga
     7561 aaacgatctc cagcatataa actactattg aaatctttaa tataatcaag tacttctttt
     7621 ttaaaaagga aagacgctgt atgaaaaagt cttacatcca ataagtcttt agtttttaaa
     7681 atctgttttt tcacatgatg aaacatatgg gatggagttc cattctcata aaaaactaaa
     7741 gattgatgcg cacaacctgc taacgaatga tcactctcca ttgcatttac ttgtttttgt
     7801 aacttcaacg gatcagtcca ataatcatcc ccctcacaaa gcgcaacata tttacctttt
     7861 actaaaggaa ataatatttg acgtaacgga gaaatacctt gagaatactg gtttcgaatc
     7921 tgaagaattg gtttaataag attaggatat gccacaacat attcattaat aatactctga
     7981 gtagcatcag aagacgcatc atcatgaaca agaatttcaa aatcaaattc tgttttttgc
     8041 attataaggc catctaaaca ctgccttata tatttttcat gattatacgt caagcaacat
     8101 atgctaactg ttattgaacc gttcatttat tttaatctta attcagcaaa acgctttatt
     8161 tccatttcac ttttataatc ctcaaacaac ttacgacaat catattgagg cacatatcct
     8221 aattctttct ttgcattttc aatgttcatt atgtacccac caccacaaac tttgtctggt
     8281 ctatatataa cttcagatgg tgactcctta ggcgaaaaaa cactaataat agtgcgaatt
     8341 tgttcttcta atgtaattgg cattcctgta cccacattat aaaagccact ttcttgttcc
     8401 acctcaacag ctttacacaa catttgacta aaatcgttaa catgaaccat atcctttgca
     8461 taatgaggat ctccccatat ctctataggt agtcctttct gagcattttc aatcatttgg
     8521 taaataggtc gcttcgtctt gactccatta ggaaagtagt acggataagg gctatagcta
     8581 tatattgttg gaagcctaaa aatgaatttt ttcaaaccgt attcttgata ataatgctct
     8641 atcaagtcta aagcagtatt tttggaaatt acatatatag catgatcacc cgtatagcta
     8701 aaatttggtt tcatatcggg ttttaaaata gtatcatgag aatacaatga aatatcaaaa
     8761 acggtttgag tataaattat cctatctaca tgacatttgc ggcaatactc taatacatta
     8821 aatcctccta ttacaataga atctaaatac tttatggggc aataagtatc catataagaa
     8881 ggtatttgag cagagagtag cataactgca tgtatatttt ccattggaag cttatcaaaa
     8941 tcttcttcct tcgtaatgtc cacagaataa tatggtattc cccttttgga aaaaaaagta
     9001 gtttcgcgac gtcctgaagc tattatttca tactcttcct tattaaagaa atttaatgcg
     9061 tattctaaca aataagaccc tgtattaccg gttgctccaa aaataataat tttctttttc
     9121 atgataaatg gttatttaag ttagatattt tttcaattaa tatattcatt gttttttcat
     9181 catatctctg atctataggc aatgcaatca tattattcgc gattgagtat tccagacatt
     9241 tagcgtctat cttattcact acgttttgcc aatattgagg tacatatacg tgctctaata
     9301 ttaattgttg gcgaagccca gctttgctcg tataaaaagg atatatcaac gggacatttt
     9361 gattttcaga aatactaaaa tcaaatttat taaatgcagt taatgcactg tagagaagat
     9421 gataattaaa acgacgcctt tcaattattg agacgtaatc caaagaagac aaaattttat
     9481 cagacaatac agacattcta tgtatctctt gatttgacat cctttcttca gattcttgaa
     9541 aatctttata atacccctct gcagagtcag ttatacgccc tatcaagtag ttaatattat
     9601 caataggatt ataaatcggg aaatcaatat ccagtaacgc agttgtgtac aaataagcgc
     9661 catctggaac tccaaaaaat ttacgggcag aataaaatgt atctacccct tcaattggtt
     9721 ttgcaaaaaa agcttgtgca ttatcaacta ttaagttagg ataaaaccga gataaataaa
     9781 gaacagtatc ttgttttaag ccgaaataat tagtatatag aaaagcctct gagctttcta
     9841 tttttttatc aaacacagga tccagtaaac tatttatatg ataatattca tactttacat
     9901 ttaatttcat gagaggttct attatcacat cacaagtgta atatggaata tacacttttg
     9961 tataccgtct agcttttaat atatactcaa agcattgacg agcagtactc agttttattg
    10021 caccttgatg aaaatgttct ccttcacgta tttccagttc aaaatagcca cctattgaca
    10081 tcattgtaaa ctaaatgaat ctaataacat acaagtttct tctttagaat tattcattag
    10141 tacatctatt attgataaat atggaacaaa ttctttagat tgctggggat acctttttat
    10201 tatcgtatct acaaatttca aattaatacc attttgcata aagtcttcct tattatagat
    10261 ttgttttcca cctatagcat tataataagt atctgccgat agtaacttac aaatatgaag
    10321 aactttatcc tttcctttta aagagcaatc tttaggtaaa tctgaagata gcaatatttc
    10381 agtctgaata tttagataat ctaaaatttc tttaaaacta ttagccaaga agagagccaa
    10441 ttgtctattt ggaaacataa ttatcctata caacaattcc attgtttcat gatagaaagg
    10501 agctttagag taattcaatt ccaatgtttt cataaattta cgaaaatcat ctcctatctc
    10561 tatttcattg aaatgtttat aggcactagc ccccttcaaa gtgatagtaa acattttctt
    10621 ttcaccattt accaatatat tgttacgatt cacccaccct cctttaatat aattaacatc
    10681 atcgtataca acgtatttat caacagcctt aattagctgg aaataaccta tataaggcat
    10741 aaaataaggt tgcattatac ctaatttcat ttcaatatca gatttaaaat tctttcaaca
    10801 tcttcattcg acaatccaca atacattg
//
