LOCUS       c00001_gnlPro..        14604 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|EEPNEEIB_1.
ACCESSION   c00001_gnlPro..
VERSION     c00001_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-07 21:58:56
            Original ID  :: gnl|Prokka|EEPNEEIB_1
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 14604
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..14604
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[125:4604]"
                     /cutoff="10000"
                     /detection_rule="(minimum(2, [Aminotran_5, GCV_H, GCV_T,
                     GDC-P, SoxG]) and GCV_H and GCV_T_C)"
                     /neighbourhood="10000"
                     /product="Glycine_cleavage"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      126..4604
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(2, [Aminotran_5, GCV_H, GCV_T,
                     GDC-P, SoxG]) and GCV_H and GCV_T_C)"
                     /neighbourhood="10000"
                     /product="Glycine_cleavage"
                     /protocluster_number="1"
     cand_cluster    1..14604
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(minimum(2, [Aminotran_5, GCV_H, GCV_T,
                     GDC-P, SoxG]) and GCV_H and GCV_T_C)"
                     /kind="single"
                     /product="Glycine_cleavage"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..14604
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Glycine_cleavage"
                     /region_number="1"
                     /rules="(minimum(2, [Aminotran_5, GCV_H, GCV_T, GDC-P,
                     SoxG]) and GCV_H and GCV_T_C)"
                     /tool="gutsmash"
     CDS             complement(126..2972)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Glycine_cleavage: GDC-P"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Beta_elim_lyase"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_1"
                     /sec_met_domain="Beta_elim_lyase (E-value: 5.4e-10,
                     bitscore: 32.5, seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="GDC-P (E-value: 3e-178, bitscore: 586.5,
                     seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNTHSDFASRHIGPQGEERREMLDSLGYRTLDELIADIVPADIRM
                     KAPLDLPAAKSETEALEELRSILRKNKLLKTFIGQGYYGTITPSVILRNVLENPGWYTA
                     YTPYQPEIAQGRLEMLMNFQTMVSSLTGLPVANASLLDEGTAAAEAVTMCRNARPKANT
                     FFVADTCHPQTISVIRTRAAFQGVNIIVGDCSSFDPASIGADLAGVLVQYPDTLGRICD
                     YTDFFSRVHATGALCVVAADLMALTVIREPGAFGADICIGNTQRFGIPMGFGGPHAAYM
                     SCTDALKRRMPGRLIGMSIDTLGRPAYRLALQTREQHIRRDKATSNICTAQVLLAVLAA
                     FYAVYHGQEGLKRIGTEIHLKTKSLYKALTEAGIAIENKNFFDTLLLSVPGQADAMVQK
                     ALEAGYNIRRVDADHAAISLDETATCADIAALASALAGAETSAACDCDAPAWDPVHTRQ
                     TPFCTEKAFNSYHSETEMMRYIRRLESRDLALNEAMIPLGSCTMKLNAASEMIPITWPE
                     ANSLHPFVPADQSEGIREMLSVLSDRLAKITGFAAVSLQPNAGAAGEYAGLLAIRRYQK
                     HAGEGHRNVCLIPTSAHGTNPASSAMAGLKVVPVKCDERGNIDMADLKSQAEAHKDNLS
                     CIMVTYPSTHGVYEQTIKELCDIVHANGGQVYMDGANMNAQVGLTCPGCIGADVCHLNL
                     HKTFAMPHGGGGPGIGPIGVAEHLVPFLPGHLTLGHEEGAVASAAWGSASIAAICWMYL
                     SMMGPDGLREATEMAILNANYIAKKLGHLFPVLYSGNKGLVAHECILDPRQLTHDAGLT
                     VDDIAKRLMDYGFHGPTMSFPVPGTLMVEPTESEPKKELDRFIEAMERIHAEITAIING
                     TADKEDNVLKNSPHTAEMVSADEWRHPYSRSEAAYPVSGLLIHKFWPYVGRVDNVYGDR
                     NLVCTCDTVEEFSKAVEL"
     CDS             complement(3068..3448)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Glycine_cleavage: GCV_H"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_2"
                     /sec_met_domain="GCV_H (E-value: 3.1e-47, bitscore: 153.0,
                     seeds: 13, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MHDVPENLLYSKDHEWIEIDGDIGTIGISDHAQAELSDVVFVDLP
                     EVGATVAAGDPVAVVESVKAASDVYTPVSGEILEVNEELSNDPSLINSDPYGAGWLYKI
                     RLDVPTETEDMMNATDYEEYCS"
     CDS             complement(3519..4604)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Glycine_cleavage: GCV_T_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Glycine_cleavage: GCV_T"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_3"
                     /sec_met_domain="GCV_T (E-value: 7.2e-87, bitscore: 284.4,
                     seeds: 72, tool: rule-based-clusters)"
                     /sec_met_domain="GCV_T_C (E-value: 5.8e-23, bitscore: 74.2,
                     seeds: 348, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTDTDVKSTPLATKHVELGARMVPFAGWNMPVQYTGILDEHKAVR
                     ETCGIFDISHMGQFTVAGGSAAAWLNSMLTNDINKLNVGQGQYSVMLNDRAGVIDDLIL
                     YRMEPETFFVVVNASKIDEDFAWLSAHQPAGVTLENHSDEYVGLAVQGPECGEVFSRVI
                     PGVELPPRNGISRITAEGTDLIICRTGYTGEDGFEFFCPAKEGVKWFEAFLGAGAKPCG
                     LGARDSLRLEMCYPLNGSDLSPDKTPLEAGLGFFCALDTDFIGSDILREQKANGLSRRL
                     AAIEYTGKGAPPRAHYAVHVPGGEAIGELTSGVLSPSLMKGIALAYLPAAHAKVGTELE
                     IDVRGRKFPAVVVKKPFYKKG"
     CDS             complement(4680..5801)
                     /locus_tag="ctg1_4"
                     /transl_table=11
                     /translation="MLQAGIVGLPNVGKSTLFNAVTRTRKAQAANYPFCTIDPNVGMVT
                     VPDPRLQVLSDMSGSEKIIPTLIEFVDIAGLVKGASEGAGLGNQFLANIREVDAIVQVV
                     RCFDNDDIIHELGSVDPLRDIDIINSELILADIATMEKRLSSRERKARSGDKEAKAEVA
                     LITKLLPHLNEGNPALTLEPQLDDDERKLLHSFQLLSDKKSIFACNVNEDELADAISNP
                     DAHPYVSQVKKYVAEHHNAEAIVISARIEEELIDVSEEESREFLESLGVKDSGVSDLIR
                     AVYHLLGLRTYLTTGIKETRAWTIPAGAKAPQAAGVIHTDFERGFIAAEVVHYDDLVSC
                     GGKAGAREHGKLRIEGKEYVVKDGDVIEFRFNV"
     CDS             complement(5860..6783)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_S11"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_5"
                     /sec_met_domain="Peptidase_S11 (E-value: 1.2e-54, bitscore:
                     178.7, seeds: 11, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRLFALLAGFSLCLSSTSCQSYGNSSDYIPLATPVPPQLSQPVSH
                     ALPRPANFPTRPVAIPSSAPRTPRCASACVMDALTGNVLFSHNGLQHRQVASTQKLVTA
                     MVVMEHGSLDKKVVIQPSDTKADPTKLGFRAGEVYSRRELLNAMMIRSFNDVALALARD
                     TAGSVPRFAQLMNAKARQMGMYNSRFANPNGLPADQYSTAIDMARCAYYVYRNPELRNI
                     ICKRQYAFTRANGRTLLLRNTNKLLTQNPWVTGMKTGYTNAAGRCLVSSAGVNGRHVIV
                     VVLGCHPSRIWTESENLIRWALGSAA"
     CDS             complement(7343..8470)
                     /locus_tag="ctg1_6"
                     /transl_table=11
                     /translation="MTPREAAIALNLIPGLGPVRIMRLLQVFASPELILESPSSLLMEI
                     PGVGAQLACRISSWRSIVNPYRELELADNAGAAVTTVFDDSYPSSLRALPDPPIVLYSW
                     GNWNGTDAERSIAVVGSRMATHYGRLCARNISHDLAEAGVTVISGLARGVDTEAHTGAM
                     DAEGRTIAVIGAGLNKLYPRENRNLAQRIADGHGAVVSEFPMDLSPSRTTFPMRNRIVS
                     GWSRATLVVEASGRSGALITARTAAEQGREVFCIPGPVDRHSSDGCHALIRDGAILATG
                     ASDILQDMNWAVPEQGLPLFSPCPPAGASTPLLPTLEEKEILHAIRLGFNTIDTLCTSL
                     GKAAHTITPLLAKMQIAGQITPDAGGYFSINGREL"
     CDS             complement(8467..9579)
                     /locus_tag="ctg1_7"
                     /transl_table=11
                     /translation="MKIVHLVPSMESGGVEQVVMELGSGLSSRGVENIVVSGGGRLVPR
                     LEKEGSRHILMPIGKKSISTLFRIGALRALLQAVRPDILHLHSRVPAWAGYLAWKKLPP
                     EDRPGLVTSVHGFYSVNRYSAIMSRGERVIAVSNCIRDYILDHYPSTPPDHIRIIPNAI
                     SPDQYHPAYSPSREWLTGWFMSYPELKGKFTLCLPGRITRLKGHLDLIPVVRQLLEQGI
                     PAHAVIVGEAKKGKEEYKNEVLRAIERSGVSQSFTWTGHRQDLREILSTCSVTLSLTKS
                     PEAFGKSTLEALALGKPVAGYAHGGVKEQLDAFLPEGNVAVGDTASMADLLARWHAQPP
                     PLPRQIPSPYNMQDMIQAHLDVYQELTPYS"
     CDS             complement(9576..10592)
                     /locus_tag="ctg1_8"
                     /transl_table=11
                     /translation="MNKSMPPTKNFLLSGGNWIACTPPPLHNAAYMNIRILSDGKQGHL
                     NQSLGLAQALISKAGGTVETVDLQGLSLLGKIRKVVTGSDIPRPDLFISAGHATHIPLI
                     CARHHFKTRAVLCMKPTLPCSFFDLCLIPRHDLDSGRDYTDTDIFPTQGALHPMRPDPS
                     VPKDTTLILIGGPSKDFDWDDESMLNQLASISIHTPGHLVLTTSRRTPDGFAEKIRTAV
                     PELTVVPVEETRPGWVARHLAHASAAWVSQDSVSMVYEALGSGAPVGILSVPRRHGSRK
                     SRILSGLETLEKEGMVTGYSDWKKQNFRLTAPGSPLLEADRAADYILSRFFPQLRAL"
     CDS             10602..11663
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_16"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1019:4Fe-4S dicluster domain (Score: 66.5; E-value:
                     1e-20)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_9"
                     /sec_met_domain="Fer4_16 (E-value: 3e-20, bitscore: 66.5,
                     seeds: 227, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VLTPDSSVIKDSLCAVSRQLGFSGCRVARAEKSPHAEKLFQWLER
                     GWHAGMEWMARSPERRTDPAEVLPGCRSVICLSYDYDSPGRRPEGEGSICLYAHGKDYH
                     GILEEKLADLQELLSIYGGKQRGYVDSGPVMERDHAEACGLGWRGKSGLIVRRKGGSRF
                     FIATLLTTLELEPDAPVSNGCGSCRRCAALCPTGAIMENGQVDAGRCLSYWTIEHRGAI
                     PEEIRPLIGTRLYGCDTCVTVCPWNGKPLPDVDERFRMSRLLASIPLRGLLSLDAGGFA
                     ALFRNSPLKRLKREGLLRNGCVVLGNAGTPDDIDFLKALYGESPLVEEHASWAVERILR
                     RHGRHASSSGARD"
     CDS             11782..12159
                     /locus_tag="ctg1_10"
                     /transl_table=11
                     /translation="MARLFGTEIPNEKRIEASLPYIYGIGRSTSKRILEQAGINPDIRT
                     GQLTDEQLTKIVQVITTDGILIEGDLRREKQSILKRLTSINCYRGQRHRRGLPVRGQRT
                     RTNARTRKGKKKTVGAQAKKK"
     CDS             12193..12744
                     /locus_tag="ctg1_11"
                     /transl_table=11
                     /translation="MASEEITNETAEQPVEAAASAPVAETPAAAVSAPEEIKKPEPRKD
                     IFAELGLGGDDDKPKILKAKGSKNVSTGVVHVSSTFNNTVVTVTDQRGNVIGWSSAGKM
                     GFKGSRKSTAYAGQVVCQDACRQAMGHGLREVEVRVKGPGSGRESAVRAVQTIGIEITS
                     IKDVTPIPHNGCRPPKARRV"
     CDS             12780..13391
                     /locus_tag="ctg1_12"
                     /transl_table=11
                     /translation="MARYTGPRDKVSRRFGVALFGSTKALEKRPFPPGQHGMRAGRKKK
                     SDYGVMLAEKQKLRFQYGVLEGQFRKYYAEAARRRGITGDILLQLLELRLDNVVYRLGF
                     SNTRAGARQLVSHGHITVNGKKTNIASYSCRPGDVIAVGGKASSQQLVTRSLDLTQATV
                     VPDWLECDRDKLTGKIARVPSKEEIAPIVNEQLIVEFYSR"
     CDS             13524..14291
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HAD"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_13"
                     /sec_met_domain="HAD (E-value: 3e-35, bitscore: 115.8,
                     seeds: 107, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTDDWKKRGAALFDMDGTLLPWDTQYIFSCFVVRRHPWRRLLIFL
                     FLACIPLYILRIWDENRMKRAYLMYLWGLPAETVREYGRKFAEMAQEWIYPELKERLAG
                     YRKKGYLCLMVSASPSFYVKPLGELLGFDEVLGTDVLLEERMPAMPELPNGNNKGAVKV
                     ERLRERNVLPEHGVLENAVAYSDSAADLPMLLSCRRRVLVNPSPALKEDRLLDGAECLY
                     PARPWKGRFGKIWRIGFFVMGLVDVNNVKSMTC"
ORIGIN
        1 gcttttgggc ttaattgttt tctggatatg tttgctcttt cggattggaa atccgattct
       61 tgaacataag aaaaaggctg ctccaaatga atggaacagc ctttttgaaa ggaaggatga
      121 gatttttata actctacggc cttggagaat tcctccaccg tgtcgcaggt gcagaccaga
      181 ttgcggtctc cgtacacatt atccacccgg cctacatacg gccagaattt gtgaataagg
      241 agaccggaga ccggataagc cgcttcactg cgggagtagg ggtgccgcca ttcgtcggcg
      301 gagaccattt ctgcggtatg gggcgagttt ttcaggacgt tgtcttcctt gtctgccgta
      361 ccgttgataa tggccgtgat ttccgcatga atgcgttcca tggcttcaat gaagcggtcc
      421 agttcttttt tgggttccga ttccgtcggc tccaccatca gggtgcccgg aacggggaag
      481 gacatggtgg ggccgtggaa gccgtagtcc atgagccttt tggcaatgtc atccaccgtg
      541 aggccggcgt catgagtgag ctgacgcgga tccagaatgc attcatgcgc caccagcccc
      601 ttgttgccgg agtagagaac cgggaagaga tgtccgagtt tcttggcaat gtagttggcg
      661 ttaaggatgg ccatttccgt ggcttccctg aggccgtccg gccccatcat ggagaggtac
      721 atccagcaga tggcggcgat ggaggcgctt ccccacgccg cagacgctac ggccccttct
      781 tcatggccca gcgtgaggtg cccgggcagg aagggtacga ggtgttccgc tacgccgatg
      841 ggcccgatgc cgggaccgcc gccgccgtgc ggcatggcaa aggttttatg caggttcagg
      901 tggcagacgt ccgcgccaat gcagccgggg caagtcagac ctacctgggc attcatgttg
      961 gcgccgtcca tgtacacctg gccgccattg gcatggacga tgtcgcagag ttccttgatt
     1021 gtctgttcat ataccccgtg cgtggagggg tacgtgacca tgatgcagga gagattgtcc
     1081 ttatgggctt ccgcctggga tttcaggtct gccatgtcga tgttgcctct ttcgtcgcat
     1141 ttgacgggca ccaccttgag gccggccatg gcggaggatg cgggatttgt tccgtgggcg
     1201 gaggtgggaa tgaggcagac attgcggtgg ccttctccgg cgtgcttctg gtagcggcgg
     1261 atggccagta gcccggcata ttcccctgcg gcgccggcgt tgggctggag ggatacggcg
     1321 gcaaagccgg tgattttcgc cagacggtcg gacaggacgg agagcatttc ccggatgcct
     1381 tccgactggt ccgccggaac aaagggatgc agggagttgg cttccggcca cgtgatggga
     1441 atcatttcag aggcggcgtt cagcttcatc gtgcaggagc ccagagggat catggcttca
     1501 tttagagcca ggtcccggga ttccaggcgg cggatgtagc gcatcatttc cgtttcggaa
     1561 tggtaggagt tgaaagcctt ttccgtgcag aaaggcgtct ggcgcgtgtg gacgggatcc
     1621 caggcaggag cgtcgcaatc gcaggcggcg gatgtttccg caccagcaag ggcggaggcc
     1681 agtgccgcta tatccgcaca ggttgcggtt tcatccagag agatggctgc gtggtcggca
     1741 tccaccctgc ggatgttata cccggcttcc agggcttttt gcaccatggc gtccgcttgt
     1801 ccgggaacgg acagcagcag ggtgtcaaag aagtttttgt tttcaatggc gatgccggct
     1861 tccgtgagcg ccttgtacag gcttttggtt ttcaagtgga tttccgtgcc gatgcgtttg
     1921 aggccttcct ggccgtggta tacggcgtaa aaggcggcaa gcacggccag gagcacctgg
     1981 gcggtgcaga tgttggaggt cgccttgtcg cggcgaatat gctgttccct cgtttgcagg
     2041 gccaggcggt aggccgggcg gcccagggta tctatggaca tgccgataag gcggccgggc
     2101 atgcggcgtt tgagagcgtc cgtgcaggac atgtaggcgg catgggggcc gccgaagccc
     2161 attgggatgc cgaagcgctg cgtgttgccg atgcagatat cggctccgaa ggcgccgggt
     2221 tcccggatga cggtaagggc catgagatcc gctgccacga cgcagagcgc gcccgtggca
     2281 tgcacgcggg aaaagaagtc cgtgtagtcg cagatgcggc cgagcgtgtc cggatattgg
     2341 acaagcactc cggccagatc cgcaccgatg gatgcggggt caaaggagga gcaatctccc
     2401 acgatgatgt taacgccctg gaaggcggcg cgggtacgga tgacgctgat ggtctggggg
     2461 tggcaggtgt ccgccacaaa gaaggtgttt gctttggggc gcgcgttccg gcacatggtg
     2521 actgcttctg ctgctgcggt gccttcatcc agcagggagg cgttcgctac cggcagccct
     2581 gtcagggaag agaccatggt ctggaaattc atgagcattt ccagccgtcc ctgggcgatt
     2641 tccggttgat aaggggtgta ggccgtgtac cagccggggt tctccagtac attgcggagg
     2701 atgacggagg gagtgatggt gccgtaatag ccctggccaa tgaaggtttt caggagcttg
     2761 tttttccgca gaatggaacg gagttcctcc agggcttccg tttccgattt ggctgcgggc
     2821 aggtccagcg gggccttcat gcggatatct gcggggacga tgtccgcaat gagttcgtca
     2881 agcgtccggt agccgaggct gtcaagcatt tcccggcgtt cttccccctg ggggccgatg
     2941 tgccggctgg caaaatctga gtgggtattc atgtggtatc tctggctggt aatagcgtcc
     3001 ggccgcggaa cgggccaaac aaaatgcccc gggatggaat caccggggcg ggggagggaa
     3061 gaatggttca ggagcagtat tcctcgtaat ccgtggcgtt catcatatct tccgtttccg
     3121 tgggaacgtc caggcggatt ttgtacagcc agcctgcgcc gtaggggtcg gagttaatga
     3181 gggacggatc attggaaagc tcttcgttca cttccaggat ttctcctgaa acgggggtgt
     3241 acacgtcgct ggcagctttg acagattcca cgacagcgac agggtcgcca gctgcgacgg
     3301 tggcgcctac ttcgggaagg tctacaaaga cgacatcgga gagttcggcc tgggcatggt
     3361 cggaaatgcc gatggtgccg atgtccccgt caatttcaat ccattcgtga tctttggaat
     3421 acagcagatt ttctggtacg tcgtgcataa gatgtaattg tttgaagtga gagtgtagta
     3481 aaatgaggtg tttgtcagtt tatttttgcg ccgtagtgtc agcctttttt ataaaagggt
     3541 ttttttacga ccacggctgg gaatttcctt ccccttacgt caatttccag ctccgtgccg
     3601 accttggcat gggcggcagg caggtaggcc agggcaatgc ccttcatcag cgaaggagag
     3661 agcacgccgc tggtaagttc tccgatggct tctccaccgg ggacgtgcac ggcatagtgg
     3721 gcgcggggag gagctccctt gccggtgtat tcaatagcgg ccagccgacg gctgaggccg
     3781 ttggcttttt gttcccggag aatatcggaa ccgatgaagt ccgtatccag cgcgcagaag
     3841 aatccgagcc cggcttccag aggcgttttg tccggagaga ggtcggagcc gttcagagga
     3901 tagcacattt ccagacgcag gctgtcgcgg gcgcccaggc cgcagggttt ggctcctgct
     3961 ccaagaaagg cttcaaacca tttgacgcct tccttagccg ggcagaagaa ttcaaaacca
     4021 tcttccccgg tatagccggt gcggcagata atgagatccg tcccttccgc cgtgatgcgg
     4081 gagattccat tgcggggggg aagttccacg ccggggatga cgcgggagaa tacttctccg
     4141 cattcgggac cttgaacagc cagccccacg tattcgtcgg agtggttttc cagagttacg
     4201 cctgcaggtt gatgggcgga aagccatgcg aagtcttcat caatcttgga ggcgttcacc
     4261 actacgaaga aggtttccgg ttccatccgg tacaggatga ggtcgtcaat gactccggcc
     4321 ctgtcattga gcatgacgga gtattgcccc tgccctacat tcagtttgtt gatgtcattg
     4381 gtcagcatgg agttcagcca tgccgcagcg gaaccgccgg ctaccgtgaa ctgccccatg
     4441 tgggagatgt caaaaatgcc gcaggtttcg cgcactgctt tgtgttcgtc cagaatgccg
     4501 gtgtactgca ccggcatatt ccagccggcg aaaggaacca ttctggctcc cagttcaacg
     4561 tgtttagttg ccaggggggt ggatttgacg tctgtatcag tcatgaggcg atgtgaaggt
     4621 tatgagcaat ctgcccctta tatcagtaaa agtcaatgga attccggtaa cgcttccgtc
     4681 tagacattga agcggaattc gatgacgtcc ccgtctttga cgacatattc ttttccttcg
     4741 atgcgcagct tgccgtgttc cctcgctccg gccttgccgc cgcaggaaac caagtcgtcg
     4801 tagtgcacta cctccgcggc gataaaaccg cgttcaaagt ccgtgtggat gacgccggcc
     4861 gcctggggtg cttttgcccc ggccggaatg gtccaggccc gcgtttcctt gattcccgtg
     4921 gtgaggtagg tgcgcaggcc cagaaggtgg tacacggcgc ggataaggtc ggaaacgccg
     4981 gagtccttca cacccaggga ttccaggaat tcgcgggatt cttcctccga gacgtcgatg
     5041 agttcctctt caatccgggc ggagatgaca atggcttccg cgttatggtg ttccgctacg
     5101 tattttttca cctgggagac gtagggatgg gcgtccgggt tggagatggc gtccgccagt
     5161 tcgtcttcat tgacattgca ggcgaaaatg ctttttttat ccgaaagcag ctggaaagaa
     5221 tggagcagct tgcgttcatc gtcgtccagc tgcggttcaa gggtgagggc gggattgcct
     5281 tcgttcaggt ggggcaggag tttggtgatg agggccactt cggccttggc ttccttgtcg
     5341 ccgctgcgtg ccttgcgttc gcgggaagag agtctctttt ccatggtggc gatatccgcc
     5401 agaatgagtt ccgagttgat gatgtcaatg tcgcgcagag gatccacgga accgagttca
     5461 tggataatat catcattgtc aaagcagcgg actacctgca cgatggcgtc cacttcacgg
     5521 atgttcgcca gaaactggtt gcccaggccg gctccttccg aggctccctt gaccagaccg
     5581 gcaatatcca cgaattcaat aagcgtgggg atgatttttt cagaaccgga catgtcggaa
     5641 agaacctgca ggcggggatc cgggactgtt accataccca cgttcgggtc aatggtgcag
     5701 aagggatagt tggccgcctg ggccttgcgc gtccgggtga ccgcattgaa tagagtggat
     5761 ttgccgacgt tggggagacc tacaatacct gcctgtaaca taggcaggac tgatagcggg
     5821 tcacgccgtg aaagtcaaat accaattgcc gacgggcatt tatgcggcgg atcccagagc
     5881 ccatctgatc aggttttccg attccgtcca gatacgggac ggatggcagc cgaggacgac
     5941 gacgatgaca tggcgcccgt tgacgccggc tgaggaaacc aggcagcgtc cggcggcgtt
     6001 cgtgtatccg gttttcattc cggtaaccca ggggttctgg gtgagcagct tgttggtgtt
     6061 tctcagcaga agcgttctgc cgttggcgcg ggtaaaggca tattggcgtt tgcagataat
     6121 attgcgcagt tccgggttgc ggtacacata ataggcgcag cgggccatgt caatggcagt
     6181 ggaatattga tccgccggga ggccgttggg attggcgaag cgtgagttgt acatgcccat
     6241 ctgccgggct ttggcattca tcaactgggc gaaacgggga acggaacccg ccgtatcgcg
     6301 ggccagagcc agggctacgt cgttgaaact gcggatcatc atggcattga gcagttcgcg
     6361 gcgtgaatag acttcccccg cccggaatcc cagtttggtg gggtccgcct tggtatcgga
     6421 aggctggatg accacttttt tgtccaggct gccgtgttcc atcacgacca tggccgtcac
     6481 gagtttctgc gtgctggcta cctggcggtg ctggaggccg ttgtgggaaa agagcacgtt
     6541 gccggtaagg gcgtccatga cgcaggcgct ggcgcagcgg ggcgtgcgtg gggcgcttga
     6601 ggggatggct acgggacgtg tggggaaatt ggccggtcgg gggagggcat gggaaaccgg
     6661 ctgggagagt tgtgggggaa cgggcgttgc aagggggatg tagtcacttg aattcccgta
     6721 cgattggcag cttgtggagc tcaggcaaag ggagaatcct gcaagaaggg cgaataaacg
     6781 catgtcttgt tgctacagta agaagtttcg ttcatcaagc ccaaactccg catttgaaag
     6841 agagccggac gaaaaaggcc gcggatcgga caatccgcgg ccttttttct ctattaacta
     6901 cctatggaac caaaaaccac cctgaacgga ttttgaattg cttttcccat ccgtcggaca
     6961 gatcttgtga aggatgagac tccaggcagg agtgatgcgt tcaaaatatg ttcgtcaaca
     7021 attcttttta agaggtgttg ccgtatgagc ccgagcctgc gtccagtaaa tatggcagag
     7081 attttttccg aacatatttt gtttttcgcg agcatgtaaa tttaccgcag gcatttaaaa
     7141 tgccggggat gtcctgccga tatatttaat ttttggaata aaattattga aggaaaggat
     7201 ttggcgactg ttttaagacg tttttttgca tccggatgga aaggttttta tacgggagat
     7261 ggacggcgct cccttccggt tccatggtca gggagaggag gcccggacct ggcgttttcc
     7321 ccggcggaaa agcggaatct tcctaaagtt ccctgccgtt aatggagaaa taccctccgg
     7381 cgtccggagt aatttgccct gcaatttgca ttttggccaa aagcggggtg atggtatgcg
     7441 ccgcttttcc cagagaggtg cagagggtgt caatagtatt gaaacccagt ctgatggcgt
     7501 ggagaatctc cttttcttcc aaagtgggaa gcagtggggt tgaggctccg gcagggggac
     7561 atggcgagaa gagaggcagt ccctgttccg gaacggccca gttcatgtcc tgcagaatat
     7621 cggaggctcc ggtagccagg atggctccgt cccggatgag ggcatggcat ccgtcggaag
     7681 aatgccggtc aaccggtccg ggaatgcaga aaacctctcg gccctgttcg gccgccgttc
     7741 gggccgtgat cagggccccg ctgcgtccgg acgcctccac caccagcgta gcgcggctcc
     7801 agccgctcac gatgcggttg cgcatgggaa aagtggtgcg ggagggggac aggtccattg
     7861 ggaactcgga gactaccgct ccatgcccgt ccgcaatgcg ctgcgccaag tttctgtttt
     7921 cccgaggata cagtttgttg agacctgccc cgataacggc gatggtgcgc ccctccgcgt
     7981 ccatggcccc ggtatgggct tccgtgtcca caccgcgcgc cagtccggaa atgacggtga
     8041 ctccggcttc cgccaggtca tgggagatgt ttctggcgca aagcctgccg taatgggtgg
     8101 ccatccgtga gccgacgacg gcaatggagc gttcggcatc cgttccgttc cagtttcccc
     8161 aggagtagag gacaatgggc gggtctggga gagcacgcag ggaggatggg taggagtcgt
     8221 caaaaaccgt ggttactgcg gcccccgcgt tatccgccag ttccagttcc ctgtacgggt
     8281 tgacgatgct ccgccaagag gaaatgcggc aagccagctg cgcccccacg ccgggaattt
     8341 ccatcaacag ggaggaaggg gattccagaa tcagttccgg agaggcgaat acctgcagga
     8401 gacgcatgat tctgacaggg cccaggcccg gtatcaggtt cagggctatg gctgcttccc
     8461 ggggtgtcat gaataagggg tcagttcctg gtaaacgtcc agatgggctt gaatcatatc
     8521 ctgcatattg taaggggaag gaatttgccg gggcaggggg gggggctggg catgccagcg
     8581 ggccagcagg tccgccatgg aggcggtatc tcctacggcg acgttccctt caggaaggaa
     8641 ggcgtccagc tgttccttga ctccgccgtg ggcgtatccg gccacaggtt tgcccagggc
     8701 gagcgcctcc agggttgatt tgccgaaggc ttccgggctt ttggtcaggg agagggtgac
     8761 ggaacatgtg gaaaggattt ccctcagatc ctggcgatgt cctgtccagg tgaaggactg
     8821 ggagacgccg gaacgttcta ttgcccgcag gacctcgttt ttatattctt cttttccctt
     8881 ctttgcttct cctacaatga cggcgtgggc cgggattccc tgttccagaa gctgcctgac
     8941 gaccggaatc agatccagat gccctttcag gcgcgtgatg cggcccggca ggcacagggt
     9001 gaatttcccc ttcagttcag gataggacat gaaccagccc gtgagccatt cccgggaggg
     9061 ggagtaggcc gggtgatatt ggtccgggga aatagcattg ggtatgattc tgatatggtc
     9121 cggaggggtg gacggataat ggtcaaggat gtagtccctg atgcagttgg agacggcgat
     9181 cacccgctct ccccggctca tgatggcgga gtaccggttg acggagtaga agccgtgaac
     9241 gctggtgacg aggccgggac ggtcttcggg cgggagcttt ttccatgcca ggtagcctgc
     9301 ccacgcagga acgcgggaat ggagatgcag gatatccggc ctgacggcct gaagcagggc
     9361 gcggagggcc ccgatgcgga agagagtgga gatgcttttt ttgcctatcg gcatcaggat
     9421 gtggcgggag ccttcctttt ccagacgggg caccaggcgt ccgcctccgg aaacgacgat
     9481 attttccacg ccccgggaag aaaggccgct gcccagttcc ataacgactt gttccacgcc
     9541 tccggattcc atggagggga cgagatgtac tattttcata aggcgcggag ctgagggaaa
     9601 aatctggaga ggatgtagtc tgctgcacgg tccgcttcca gaagcgggga accgggagcc
     9661 gtcaggcgga agttctgttt tttccagtca ctgtatccag taaccatgcc ttccttttcc
     9721 agtgtctcca ggccggacag gatgcgggat ttgcggctgc cgtgtcggcg cggtacggaa
     9781 aggatgccta caggcgcgcc ggagccaaga gcctcatata ccatggagac gctgtcctgg
     9841 ctgacccagg cggcggaggc gtgcgccaga tgccgggcta cccaccccgg ccgggtttcc
     9901 tccacgggaa cgacggttag ttccggaacg gccgtccgga ttttttccgc aaagccgtcc
     9961 ggcgtccggc gcgaggtggt tagaacaagg tgtccggggg tgtggatgct gatggacgcg
    10021 agctggttga gcatgctttc gtcatcccag tcaaaatctt tgctgggccc tcctatgaga
    10081 atcagtgtgg tatcctttgg tacggaggga tccggcctca tggggtggag agctccctgg
    10141 gtggggaaga tatccgtatc cgtgtaatcg cggccggaat ccaggtcatg gcggggaata
    10201 aggcagaggt cgaaaaagga acagggaagc gtaggcttca tgcagaggac ggcccgggtt
    10261 ttgaaatggt gccgcgcgca gatgagcggg atatgcgttg catgtccggc ggaaatgaac
    10321 agatccggcc gtggaatgtc gctgcctgtg acgaccttcc ggattttccc caaaagggaa
    10381 agcccctgca ggtctaccgt ttccacggtt ccccccgctt tggagatcag agcctgcgcc
    10441 agccccaggg actggttgag gtggccctgt ttcccatcgc tcagaatccg gatgttcata
    10501 tatgcggcat tatgaagcgg cggcggggtg caggcaatcc aatttccacc ggacagaaga
    10561 aaattcttgg tgggaggcat gctcttgttc atgattccgg cgtgctgact ccggattcct
    10621 ctgttattaa agattccttg tgcgccgtgt cccggcagct tggtttttcc ggctgccggg
    10681 tggcccgtgc ggaaaaaagc ccgcatgcgg aaaaattgtt tcaatggctg gagcgcggat
    10741 ggcacgccgg gatggagtgg atggcgcgtt ccccggagcg gcgcacggat cctgcggaag
    10801 tgcttcccgg atgccgttca gtcatttgcc tgtcctatga ttatgacagc cccggtaggc
    10861 gcccggaggg ggagggtagc atttgccttt acgcccatgg aaaggattac cacggaattc
    10921 tggaggaaaa actggcggat ttgcaggagc tgctttccat ttacggcggg aagcagaggg
    10981 ggtatgtgga ctccggccct gttatggaac gggaccatgc ggaggcctgc ggcctgggct
    11041 ggcgcgggaa aagcggtttg atcgtgcgca ggaaaggggg ctcccgcttt tttatcgcta
    11101 ccctgctgac tacgctggaa ctggaaccgg acgctccggt ttcaaacgga tgcggcagtt
    11161 gccgccgttg tgcggccctg tgtccgacgg gcgcaattat ggaaaacggt caggttgatg
    11221 ccggacgctg cctttcctac tggacgattg aacaccgggg ggctattccg gaagaaatcc
    11281 gtcccctgat aggcacgcgc ctgtacgggt gcgatacctg cgtgacggtc tgtccctgga
    11341 atggtaagcc tttgccggac gttgacgaac ggttccgcat gtcccgtctg ctggcttcca
    11401 ttcccctgcg tggtcttctt tccctggatg ccggcggttt tgcggccctg ttccggaatt
    11461 ccccgttgaa aaggctcaag agggaagggc tgctgcgtaa cggctgcgtt gtgctgggga
    11521 atgcggggac tccggatgac attgattttc tgaaggcgct ttacggggag tctcctctgg
    11581 tggaggaaca cgcttcctgg gctgtggagc gcatcctccg ccgccacggg cggcatgcat
    11641 cttcaagcgg tgcaagagat taaaaataga aaaaatgatg ttttggtctt gtcaaaacct
    11701 caatttatgg tatccatctt gccccaagca atagctctgc gcgaggcaga gaaaaataac
    11761 agctagcaaa tccaatccat tatggcacgc cttttcggta cagaaatacc caacgagaag
    11821 cgcatcgagg cttcccttcc gtatatttac ggaattggtc gctcgacttc taagagaatc
    11881 ctggaacaag caggcatcaa tcccgacatc cgcacgggac agcttaccga cgaacagctc
    11941 acgaagattg ttcaagtaat caccaccgac ggcattttga ttgaaggtga ccttcgtcgt
    12001 gaaaagcaat ccattctcaa gcgtctgacc tccatcaact gctatcgtgg tcagcgccac
    12061 cgccgcggcc ttccggtacg cggtcagcgt acccgcacga atgcccgcac ccgtaaaggc
    12121 aagaagaaga ccgttggcgc gcaggccaag aagaagtaat ccgccaacct gaatttttaa
    12181 tatagcttta ctatggctag cgaagaaatc accaacgaaa ccgccgaaca gcctgtggaa
    12241 gcggcagctt ccgctcccgt cgctgaaact ccggccgccg ctgtttccgc tcctgaagaa
    12301 atcaagaagc ccgaaccccg caaggatatc tttgcggaac ttggtctggg cggcgatgat
    12361 gacaagccca aaatcctgaa ggccaagggc agcaaaaacg tttccacggg cgtggttcac
    12421 gtttcctcca cgttcaataa caccgtcgta actgtgactg accagcgcgg caatgtcatc
    12481 ggctggtcct ccgccggcaa gatgggcttt aagggttccc gcaagagcac ggcctatgcc
    12541 gggcaggtgg tgtgccagga cgcctgccgc caagccatgg gccacggctt gcgtgaagtg
    12601 gaagtgcgcg taaaggggcc cggttccggt cgtgaatccg ctgtacgtgc cgtgcagacg
    12661 atcggtattg aaatcacctc catcaaggac gtgaccccca tcccccacaa cggctgccgt
    12721 cctccgaagg cccgccgcgt ctaattgaga atcttttacc tatatagatc taatatatca
    12781 tggctcgtta taccggtccc cgcgataaag tgtcccgccg ttttggcgtt gcccttttcg
    12841 gttccaccaa ggctcttgaa aagcgcccct tccctcccgg ccagcatggc atgcgcgccg
    12901 gccgcaagaa gaaatccgac tatggcgtga tgcttgctga aaaacagaaa ctgcgtttcc
    12961 agtacggtgt gcttgaaggc cagttccgca agtattatgc agaagccgcc cgccgccgcg
    13021 gcattaccgg cgatattctg cttcagctcc ttgagcttcg tctggacaat gttgtgtacc
    13081 gcctcggctt cagcaatacc cgtgccggcg cccgtcagct tgtttcccac ggccacatca
    13141 ccgtgaacgg caagaagacg aatatcgcgt cctactcctg ccgtccgggc gacgtcattg
    13201 ccgtaggcgg caaggcttct tcccagcagc tggttacccg ttcccttgac ctgactcagg
    13261 ctactgtggt tcctgactgg ctggaatgcg accgtgacaa gctcacgggc aagattgccc
    13321 gcgtgccttc caaggaagag attgctccca tcgtcaatga gcagctcatc gtggaattct
    13381 actcccgtta atcttatttc cttctggatt tgcttcaaaa ccccggttgc ctttcggcgg
    13441 ccggggtttt gggcattcag ggggggaggg gcatggaaga gttgggtgtt gagagttaag
    13501 ggaagctggt ataggatgaa agcatgacgg acgattggaa aaaaagaggc gcagcgcttt
    13561 tcgatatgga cggcacgctc cttccctggg atacgcaata tattttttcc tgttttgtgg
    13621 tgaggcgcca tccttggaga cgcttgctga tttttctttt cctggcctgt atcccgctct
    13681 atattttgag aatatgggat gagaaccgga tgaagagggc ttatctcatg tatttgtggg
    13741 ggcttcccgc tgaaacggtg cgggaatatg gacggaagtt tgccgagatg gcgcaggaat
    13801 ggatttatcc ggagctgaag gagcggctgg cagggtatcg gaagaagggt tatttgtgtc
    13861 tcatggtttc cgcttctcca tcattttacg tgaagcccct gggcgaactg ctgggatttg
    13921 acgaagttct gggaacggat gtgcttctgg aggaacgcat gccggcaatg ccggaactgc
    13981 cgaacggtaa taataagggg gcggtgaagg tggagcgtct gcgggagcgg aatgtactgc
    14041 cggaacatgg tgttctggaa aacgccgttg cctacagcga cagtgccgcg gatctgccca
    14101 tgctgctttc ctgcaggcgg agggttctgg tgaatccttc tcctgccctg aaagaagaca
    14161 ggcttctgga tggtgcggag tgtctgtatc cggccaggcc ttggaaggga aggtttggca
    14221 agatatggag aattggattt tttgtcatgg ggttggtgga tgtaaataat gtgaaatcaa
    14281 tgacttgctg atttatcaag agaaaattct ttacttttgt gacgaaaatg tttcactttt
    14341 cttaacaagg ggggaaaaag catttttctt tccatgttag caaatcaaca attaataccc
    14401 taaccaagta atagtcatgc aaaccaagaa catcatcagt gttgcggcag ttgtggcatc
    14461 ctttgccgga gctgctcttg cgggtactcc cgtcaagatt gttgctccga ctccggttcc
    14521 cgctcctgtg gcgacttcca gcccgctgtc cggcgatatt tacgccggct acgcttccaa
    14581 ttacacctgc cgcggcattg tggc
//
