LOCUS       c00043_gnlPro..        13499 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|LKECIGIB_43.
ACCESSION   c00043_gnlPro..
VERSION     c00043_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-05 13:57:18
            Original ID  :: gnl|Prokka|LKECIGIB_43
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 13499
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..13499
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[28:3499]"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      29..3499
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
     cand_cluster    1..13499
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /kind="single"
                     /product="Fumarate2succinate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..13499
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Fumarate2succinate"
                     /region_number="1"
                     /rules="(Succ_DH_flav_C and FAD_binding_2 and (Fer2_3 or
                     Fer4_7 or SucD_FumR))"
                     /tool="gutsmash"
     CDS             29..721
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: SucD_FumR"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg43_1"
                     /sec_met_domain="SucD_FumR (E-value: 1.2e-74, bitscore:
                     239.8, seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MWLLNSSIGKKLIMSISGLFLVLFLLFHLSMNVAAVFSGEAYNMV
                     CSLLGSNWYAVAATLVLAAGVVIHFVYAIILTLQNRKARGNDRYAINARPKGVEWASQN
                     MFVLGLIVILFMLLHFSQFWYKMMFAELIGHHEVALGSAMVSPQDGAAFINYYFQGNAV
                     ITVLYLIWYVALWFHLTHGFWSAIQTIGWNNTIWMNRWECISKIVATVICGLFAIITII
                     FFLNGVGA"
     CDS             770..2713
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Succ_DH_flav_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: FAD_binding_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1027:FAD binding domain (Score: 194.5; E-value:
                     1.1e-59)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg43_2"
                     /sec_met_domain="FAD_binding_2 (E-value: 2.2e-60, bitscore:
                     194.5, seeds: 62, tool: rule-based-clusters)"
                     /sec_met_domain="Succ_DH_flav_C (E-value: 1e-38, bitscore:
                     122.0, seeds: 739, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSEINSKIPQGPLAEKWTNYKNHQKLVNPANKRRLDVIVVGTGLA
                     GASAAASLAEMGFNVLNFCIQDSPRRAHSIAAQGGINAAKNYQNDGDSVYRLFYDTIKG
                     GDYRAREANVYRLAEVSNSIIDQCVAQGVPFAREYGGLLDNRSFGGAQVSRTFYARGQT
                     GQQLLLGAYSALSRQIGLGKVKMYTRHEMLDVVKVDGRARGIIARNLITGKIERYAAHA
                     VVVATGGYVNTFFLSTNAMASNGSAAWQCYKKGAYFANPCMVQIHPTCVPVKGDFQSKL
                     TLMSESLRNDGRIWVPKKLEDAKALQAGTKKGKDIPEADRDYYLERRYPAFGNLVPRDV
                     ASRAAKERCDAGFGVNSTGLAVFLDFSDAINRLGKEVVKQKYGNLFDMYEEITNDNPYE
                     TPMMIYPALHYSMGGLWVDYELMTSIPGLFAIGEANFSDHGANRLGASALMQGLADGYF
                     VLPYTIQNYLSDQIQVPRFSTDLPEFVEAEKAIKDRIQKLMNVKGKETVDTIHRKLGHI
                     MWEHIGMARDAKGLQEAIQMLKDLKKEFWSNVFIPGNADNLNTELEKALRVADFIEIGT
                     LMAHDALDRAESCGGHFRTEHQTEEGEALRHDDKFMYVSCWEYQGEDKDPVMLKEDLNY
                     EFVVPQTRNYKK"
     CDS             2744..3499
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Fer2_3"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_8"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg43_3"
                     /sec_met_domain="Fer2_3 (E-value: 1.3e-26, bitscore: 82.5,
                     seeds: 38, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_8 (E-value: 2.7e-12, bitscore: 36.8,
                     seeds: 153, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 2.9e-06, bitscore: 17.5,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDKDISVTLKVWRQRGPKEKGQFETYKIEKINQSVSFLEMLDILN
                     EQLVNEGKEPIVFDHDCREGICGMCSLYVNGHPHGPATGATTCQLYMRRFHDGETITIE
                     PWRSAGFPVIRDLMVDRYAYDKIIQAGGFTSVNTGGVPDANAIPIPKKDADLAMDAAAC
                     IGCGACAAACKNGSAMLFVSAKVSQLALLPQGKVEAARRAKAMVAKMDELGFGNCTNTR
                     ACEMECPKNISVSNIARLNREFICAKLQD"
     CDS             complement(3536..3646)
                     /locus_tag="ctg43_4"
                     /transl_table=11
                     /translation="MKKPRCKYTDFSIPVKGYNAKLCFTTYNKNKKAPFF"
     CDS             3922..5133
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Radical_SAM"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg43_5"
                     /sec_met_domain="Radical_SAM (E-value: 2.9e-17, bitscore:
                     53.2, seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDKKRTTSSFRAMSTERKLESIFLFVTGRCNAKCAMCFYAQEMDK
                     KQPDLTFDEIKKISETAGQFNRLWISGGEPTLREDLPEILELFYKNNHIKDVNIPTNGL
                     KPDRIVEWIKRFRQNCPDCNINVSLSLDGFGTTHDTQRGVPGNFYKTLETLRKIQENFG
                     DDGKVLKNIATVITKYNIDQIEDFMTWVYGRFRTSTHTIEAARGMTRDDGVKILTESTL
                     RKIQDDISPIYSAYADRMVADTTGLRKPITRFFYLGLIRTLYNVRASNIDHPTPWGMDC
                     TAGETTLVIDYDGRFRACELREPLGNIKEYGCDISKVMNSEAMKQEIAAIGHGYKANCW
                     CTHGCWITSSVIFNPRKMIRSVYKGYRETKRLNHPLAINEQKLQTMEAKYHLDIERLRQ
                     LNIR"
     CDS             5167..6399
                     /locus_tag="ctg43_6"
                     /transl_table=11
                     /translation="MKILLVTRGSQGDVLPYLAIAAELERRGHEVTINLPQIFEETVKP
                     YGFKYVLQQFDDIGGMIDSAAQNSHKFRPFLKWMRNVIDKQFDQLIPLLKEHDILVSTN
                     SEFAVASIAEYCKKPLIRTAYAPFLPGKKIPPAVLPFPKPNPIITPAILWKLMNRMTNF
                     MVKDTINKNRAKYGLAPIRNFGYHAGERSYNYLLFSQHLGNVDPDWTFEWSIGGYCFND
                     TFQYDEKAYEEMISFVDSAQSPIIFFTLGSCSSKDGNRFSKALVDICKKHDYRLIIGSG
                     WAKTGITLQADKHLFLMKQPVPHNLIFPHCDGVIHHGGCGTTHSVGRAGKPQLITPLII
                     DQPYWSYRIHQLGLGPEGVKIAKASEQEIERKVCDLVTNPLYKKNAAHIGEMIQKEGGI
                     KNICDSIERFQ"
     CDS             complement(6605..9742)
                     /locus_tag="ctg43_7"
                     /transl_table=11
                     /translation="MIRNIINLKAIILYFGLILCLIAGMPTPAYGSFSYPVKDESYVLV
                     INSYVDGERWSGNLLNMISKFATPEEYTLRIDHMSVMLVDTPEKLKEKQEAFFEVNKKK
                     PDGIIYLGVNGWAFMRDKIREKWGDIPTLVCSETGEMAEDECYFNQRHSSDRVIPLQEA
                     VKGYNATGLVIPYYVKGSIDLVKELIPGLKRLIFISDRRYVSTWLRDEMEKHMETSFPE
                     GKVDFYTEGSCSMDSLMAVLSEKDPHRATAVMYYSWITEKPFLNHSLLYSTLYQGINGI
                     SRHPVFSLYDMGVEEGYTIGGYYNSAKTIETALIPLLQQVYNGEDMGKIPVSTVNDPHK
                     YLNYASLISAISNEDNFPRDAIYLNAPPSFLEKYWMQLLGFLIFFLVVVFLAGHYVYRS
                     KQKMKEVELRLLSRYRDLFNNMPLPYIRQRLIREGSQIDVQVLDVNHAFEEKIAPKDFV
                     VNKRGKEIANLIGGSYPLLLSAVPTVLESGKSFTYEYYFEPTGLYYTIIIMPTSEENVV
                     DAFFIDITDIHKFQTHLKAMNHKLAMALEAADLLPWRYNLAEGKIIYESKVHPGDNIET
                     AEVHTHEVSLKEYFSKIHPSFRACVEKAFDDLCNGKIKKVRKEYCLERLIPGEDRHEWE
                     EIQVMAEYDASGKPKALIGSTISITERKQLEHDLRMARDKAEESNKLKSAFLANMSHEI
                     RTPLNAIVGFSNILASTDDLEDKKEFADIIENNNSLLLQLINDILDLSKIEAGTLEFTY
                     DYVDINAVLRDLEQSAHLKNKNPDVQISFKDYLEPCVIYTDRNRLSQLMINLLNNAMKF
                     TQAGSILFGYKLKDDNTLWFYVEDTGCGIPENKRKDIFGRFVKLNTFAQGTGLGLSICE
                     MIVTQMKGTIGVDSMEGKGSRFWFTLPFQPKKELLPNEEQKPVTLEKIARSEVTILIAE
                     DNSSNYRLFESILKPEYKLIHAWNGKEAVELFHQHKPQLILMDIKMPVMDGYEATAEIR
                     KVSASVPIIAVTAYAFAQDEQRIINSGFDAYTAKPINGKILKDKISTLLTHRIILM"
     CDS             9972..10748
                     /locus_tag="ctg43_8"
                     /transl_table=11
                     /translation="MELMDMKDYDIDFKEKRTNGYLIATLFIIVGILFLLRNLGMIDPS
                     LFDLLVSWPMLLVVSGIFTIFHRNPVGGMLLVGVGVYFLFPQLNWITNDFLRVYWPLGL
                     ILLGLVIMLKRKDSIRTKKHKRPFNHPPFGHRKPNDEINYETDNGFVSVDTTFNSVRHI
                     VLDPVFKGADIDVSFGNVILDLKKTTLEADETIINIDSSFSGVVIYVPKGWLVRLKVGS
                     FLAGCQDMRDLTETTDMTHTLYICGDLSFSGLELRD"
     CDS             10756..11550
                     /locus_tag="ctg43_9"
                     /transl_table=11
                     /translation="MQEHPITTSILHKGQGSLLLLLAIAIQCALLTLYGDLPLSITLVD
                     SLLSIALFAVAGYYLWYVQCTLHIMQARVAFAVLVQIACIAGCSILLQIFGLEDWEEFS
                     ITIPVRFLFGLMAWIILSQWYASRERKSEAEPIVRQMEEKTAPPPTTVPEEILDRISVK
                     DGTRIHIIPIKEIFYLQACGDYVTLFTTSGQHVKEQTMKYFERSLPSPEFVRIHRSYIV
                     NTEQILRVELFGKETYQVRLKDGTYLRASSAGYKLLKERLSL"
     CDS             complement(11888..12406)
                     /locus_tag="ctg43_10"
                     /transl_table=11
                     /translation="MKKYWHIALMLFCVLMITSCGDDDEALEVDEVWKVQNEEAFQAQM
                     LVPGFEQLSSQSNAGFILYKVLKTGESKEPIYYTSKVECYYKGSFINGEVFDDRSFEAG
                     EPAELTVSDMVDGFATALQNMHPGDRWEIWIPQQMGYGSAGRSASGSVIIKPYTTLIFD
                     LEVTRIVKE"
ORIGIN
        1 acaattaaat aacttaaatt attatcttat gtggttactt aattcttcta tcgggaagaa
       61 gctgataatg agtatatcag gcctctttct tgttctgttc ttattgttcc acctgtcgat
      121 gaacgtggcg gccgttttct ccggagaggc ttataacatg gtttgttcgc tgttgggctc
      181 taattggtac gctgtggcag ctactctcgt attggccgca ggcgttgtga tccacttcgt
      241 gtacgctatc attcttacct tgcaaaaccg taaggcacgt ggtaacgacc gttacgctat
      301 caacgctcgt ccgaaaggcg tggaatgggc atctcagaac atgttcgttt tgggtttgat
      361 tgttatcctg ttcatgctgt tgcacttcag ccagttctgg tataagatga tgttcgccga
      421 attgatcggt catcacgaag ttgcattggg gtcagctatg gtatctccac aagacggagc
      481 cgcttttatc aactattact tccaaggtaa tgccgtgatc actgttcttt atttgatctg
      541 gtacgtggct ttgtggttcc acttgactca cgggttctgg agcgctatcc aaacaattgg
      601 ttggaataat acgatctgga tgaaccgttg ggaatgtatc tctaagatcg tagctacggt
      661 tatttgcgga cttttcgcga tcattactat catcttcttc ctaaacggag taggtgctta
      721 attgcaagct acaggtttta taattaagaa cttttgaaat taaatcatta tgtctgaaat
      781 aaattctaaa atacctcaag gcccgttggc tgagaagtgg actaattata aaaatcacca
      841 gaaattggtg aaccccgcta acaagcgtcg tttggatgtt atcgtagtcg gtacaggttt
      901 ggccggagct tccgctgccg catctttggc agagatggga ttcaacgtat tgaacttctg
      961 tatccaagat tctccccgcc gtgcgcactc tatcgccgct caaggtggta tcaacgccgc
     1021 taagaactac cagaatgatg gtgactctgt ttaccgtttg ttctacgata cgatcaaagg
     1081 tggtgactac cgtgctcgtg aggctaacgt ttatcgtttg gctgaggttt ctaactcaat
     1141 catcgaccag tgcgtggctc aaggcgttcc tttcgctcgc gaatatggtg gtttgttgga
     1201 taaccgttca ttcggtggcg ctcaggtatc gcgtacgttc tacgcccgtg gccagacggg
     1261 tcagcagctt ttgttaggcg cttattcagc gttgagccgt cagatcggtt tgggtaaggt
     1321 taagatgtac actcgtcatg agatgttgga tgtagttaag gtagacggtc gtgctcgtgg
     1381 tatcatcgcc cgcaacttga ttacaggtaa gatcgagcgt tacgccgctc acgctgtagt
     1441 tgtagctacg ggtggttacg ttaatacgtt cttcttgtca accaacgcta tggcatctaa
     1501 cggttccgcc gcatggcaat gctacaagaa aggcgcttac ttcgctaatc cttgtatggt
     1561 tcagatccac ccgacttgcg taccggtgaa aggtgacttc caatctaaat tgactttgat
     1621 gtccgaatcc ttgcgtaacg acggccgtat ctgggttccg aagaaactgg aagacgctaa
     1681 agctctacag gccggaacga agaaaggtaa agatattccc gaggcagacc gtgattatta
     1741 tttggagcgt cgttatccgg cattcggaaa cttggttcct cgcgacgtgg cttctcgtgc
     1801 cgctaaagag cgttgcgacg caggtttcgg cgtgaacagc acgggcttgg ccgtattctt
     1861 ggatttctcc gacgcgatca atcgcttggg taaagaggtc gttaagcaga aatacggtaa
     1921 cttgttcgat atgtacgaag agatcacgaa cgataatcca tacgagactc cgatgatgat
     1981 ctacccggca ttgcactact caatgggtgg attgtgggtt gactatgagt tgatgacctc
     2041 cattccgggt ctgttcgcta tcggtgaggc aaacttctcc gatcacggag cgaaccgttt
     2101 aggtgcttcc gctttgatgc agggattggc cgatggttat ttcgtattac catacacgat
     2161 ccagaactat ttgtccgacc aaatccaagt tcctcgcttc agcacggatc tgccggagtt
     2221 cgtcgaggca gaaaaggcca tcaaggatcg tatccaaaaa ttgatgaacg tcaagggtaa
     2281 agaaaccgta gacactatcc accgcaaact aggtcatatc atgtgggaac atatcggtat
     2341 ggcacgcgac gcaaaaggtt tgcaagaagc tatccagatg ctgaaagact tgaagaaaga
     2401 gttctggagc aacgtattca tcccaggcaa cgcagacaac ttgaataccg agttagagaa
     2461 agcattacgt gtagccgact ttatcgagat cggtacattg atggcacacg atgctttgga
     2521 ccgcgctgag tcttgtggtg gtcacttccg tacggagcac cagacagaag aaggtgaggc
     2581 cttgcgtcat gacgataagt tcatgtacgt atcttgctgg gagtaccaag gcgaggacaa
     2641 agatcctgtc atgttgaaag aggatttgaa ctatgagttc gttgttcctc aaacacgtaa
     2701 ctacaagaag taataatcat caatctcaga aaaaattaga atcatggata aagatataag
     2761 tgtaacactt aaggtttggc gtcagagagg tccgaaggag aaaggacagt tcgagacata
     2821 caaaattgag aagatcaatc agagtgtctc tttcttggaa atgttggata tcttgaacga
     2881 gcagttggtc aacgagggta aggaaccgat cgtattcgat cacgactgcc gcgagggtat
     2941 ctgtggcatg tgttcattgt atgtaaacgg acacccgcac ggaccggcaa ctggagctac
     3001 gacttgccag ttatatatgc gtcgtttcca cgatggagag acgatcacga tcgaaccgtg
     3061 gcgttccgca ggtttccctg ttatccgcga cttgatggta gaccgctacg cttacgacaa
     3121 aatcatccaa gcgggtggtt tcacatctgt caacacaggt ggtgtacccg acgctaatgc
     3181 gatacctatc ccaaagaagg acgcagactt agccatggac gctgccgctt gtatcggttg
     3241 tggcgcttgt gctgccgctt gtaagaatgg ttccgctatg ttattcgtat ccgctaaggt
     3301 tagccagctg gctttgttgc ctcaaggtaa agtcgaggct gctcgccgtg ccaaagctat
     3361 ggtcgctaaa atggatgagc ttggcttcgg taactgtacg aacacacgtg cttgcgagat
     3421 ggaatgtccg aagaatatct ccgttagcaa catcgctcgt ttgaaccgcg agttcatttg
     3481 cgctaaatta caagactaat atttgattag tatatcatgg aaaaggcgtc tttctctaaa
     3541 agaaaggcgc ctttttgttt ttgttatatg tcgtaaaaca taatttagca ttatagccct
     3601 tgacaggaat tgaaaagtcc gtatatttgc atcgtggttt tttcataata gtattagatt
     3661 taaggttaac aaagtttggt tagggcttgt cgtgagacag gctttaattg tttatagacc
     3721 taccttttaa acatggacca taaaatactg caaatagaga ttgtttagcg tcattttatc
     3781 gtcgatcttt gcctttaaag atcatatagt atatgctaat aagtatttta tttggcttct
     3841 tatgttattt tctccgggtg ttgatcaaac acaaggaaaa aatcatgcgc cagataagac
     3901 aaatggtaaa acaaaaataa aatggacaaa aaacgaacca ccagttcttt cagggcaatg
     3961 agcacggaaa gaaaactcga gtcgatcttc cttttcgtaa caggccgatg caacgccaaa
     4021 tgcgcaatgt gtttctatgc ccaagaaatg gataagaagc aacccgacct cactttcgat
     4081 gaaatcaaga agatatcaga aaccgccggg caattcaatc gattatggat atccgggggt
     4141 gagcctacct tgcgtgagga tctaccggaa atattggagt tattctacaa aaataaccat
     4201 atcaaagatg tgaacatccc tacgaacggc ttaaaaccag accggatcgt cgaatggata
     4261 aaacggttcc gccagaactg cccggattgt aatattaacg taagcctttc cttggatggt
     4321 ttcggtacga cccacgatac acagagaggc gtaccgggaa acttctataa gacactggaa
     4381 accctgcgta agatacagga gaatttcgga gatgacggca aagtcttaaa aaatatagca
     4441 accgttatca cgaaatacaa tatagaccag atagaagact tcatgacttg ggtatacgga
     4501 cgtttccgta cctccacgca tacgattgag gctgccagag gcatgacccg tgacgatggc
     4561 gtgaaaatcc taaccgagtc aacgctacgc aaaatacaag atgacatatc ccctatctat
     4621 tctgcttatg cggatcggat ggtagcggat accaccggct taaggaaacc gatcacacgc
     4681 ttcttctatc tcggccttat acgtacctta tataatgtgc gtgccagcaa catagatcac
     4741 ccgacccctt gggggatgga ttgtacggcc ggagagacta ccttggtaat cgactacgac
     4801 ggacgttttc gtgcctgcga gctacgggaa ccgctcggaa atataaaaga atatggttgc
     4861 gatataagta aagtgatgaa tagcgaagcg atgaaacagg aaatagccgc tatcggacat
     4921 gggtataaag ccaactgttg gtgtacgcac ggctgttgga tcacctcatc cgtcattttc
     4981 aatccacgta agatgattcg ctccgtatat aaaggatacc gggaaacgaa acgattgaat
     5041 catcccctag ccatcaatga gcagaaacta caaacgatgg aagccaaata ccatctggac
     5101 atcgagcgtt tgcgtcaact gaatatccgg taaacaagac cctcatagcc cataaataaa
     5161 cgtagcatga aaatactatt agtaaccaga ggctcacaag gcgacgttct tccttatttg
     5221 gccatagcgg ccgaattgga aagacgtggc catgaggtga ccatcaatct ccctcaaata
     5281 ttcgaggaga ccgttaaacc ctacggattt aaatacgtat tgcagcagtt tgacgatatc
     5341 ggcggcatga tcgatagcgc agcgcaaaac tcacataaat tccggccatt ccttaaatgg
     5401 atgaggaacg tgatcgataa acagttcgat caattgattc ccctactaaa agagcatgat
     5461 attttagtat cgaccaactc ggaatttgct gtcgcaagta tcgccgagta ttgcaagaag
     5521 cccttgatac gtaccgccta cgccccgttc ttgccgggta agaagattcc cccggccgta
     5581 ttgccatttc ccaaacccaa cccgatcatc actcccgcta tcctatggaa gttgatgaac
     5641 cggatgacca atttcatggt caaagacacg atcaataaga accgggctaa atacggactc
     5701 gctccgatcc gcaattttgg ctatcacgcg ggagagcgtt catataatta cttgcttttc
     5761 agccagcacc taggaaacgt agatccggac tggacgttcg aatggtcgat cggaggctat
     5821 tgcttcaatg acacttttca atatgatgag aaggcttacg aggaaatgat atcattcgtc
     5881 gacagcgctc aaagccctat tatctttttt accctcggga gttgtagttc caaggatggt
     5941 aaccgtttca gcaaagcctt ggtcgatatt tgcaagaaac atgattatcg gctcatcatc
     6001 ggttccggtt gggcaaagac aggaatcacc ttacaagcgg ataaacattt attcttaatg
     6061 aagcagccgg ttccgcataa tttgatattc ccgcactgcg acggcgttat ccatcatgga
     6121 ggttgcggca cgacccatag cgtaggaagg gcgggaaagc cccaattaat cactccgttg
     6181 attatcgatc aaccctattg gtcctatcga atccaccaat tagggttagg gccggaaggg
     6241 gttaagatag cgaaagcgag cgagcaggag atcgaacgca aggtttgtga tctggtcacc
     6301 aatccgcttt ataagaaaaa tgccgctcat ataggcgaga tgatccaaaa agagggaggt
     6361 ataaagaata tatgcgactc tatcgaaaga tttcaatgag gcataagttc ctattagatt
     6421 ttattacatg ttacaaaaca caatttagca cttaaactgt tgacaaataa cagtaactcc
     6481 gtatatttgc accgtggttt tttcataata gtattagatt taaggttaac aaagtttggt
     6541 tagggcttgt cgtgagacag gctttaattg ttttatgagg tctgcttccc gcaaagccct
     6601 tcgattacat cagaataatc cgatgcgtca ataaagtcga tatcttgtct tttaagatct
     6661 tcccattaat cggtttcgcc gtataggcat caaatccact attaatgatc cgttgctcat
     6721 cttgggcgaa agcataagcc gtcaccgcga taataggtac gctagcagaa accttacgaa
     6781 tctctgcggt agcctcgtat ccatccatga ccggcatctt tatatccatc aagatcaatt
     6841 gcggtttgtg ctgatgaaat agctctacag cctcctttcc attccatgca tgaatcaatt
     6901 tatattcagg ctttaatata gactcaaaca ggcgataatt actggaattg tcctcagcga
     6961 tcaagatcgt aacctcactt cgggcgatct tctccaaagt aacaggcttc tgctcttcat
     7021 taggcaataa ttctttcttc ggctgaaaag gcaatgtaaa ccagaaccta gagcctttcc
     7081 cttccataga atcaacccct atcgttcctt tcatctgggt aacaatcatc tcacagatgc
     7141 ttaaacccaa tcctgttcct tgagcgaaag tattcagttt cacaaaacgt ccgaaaatat
     7201 ctttccgttt attctccggg attccgcagc ccgtatcctc tacatagaac cacaacgtat
     7261 tatcatcctt caacttatag ccaaataaaa tcgatcctgc ctgcgtaaat ttcatggcat
     7321 tgttcaacag attgatcatc agttgagaca gacgatttcg atccgtataa atcacgcaag
     7381 gctccagata atccttaaat gagatctgta catccggatt cttattcttc aaatgagccg
     7441 attgctccaa atccctcaat acagcgttaa tatccacata gtcataagta aactccaagg
     7501 tacccgcctc gatctttgat aaatccaaga tatcgtttat caactgcaac aatagggaat
     7561 tattattctc gataatatca gcgaattcct tcttatcctc aaggtcatcg gtcgaggcaa
     7621 ggatattaga gaaacctacg atcgcattta acggtgtacg tatctcatgg ctcatatttg
     7681 ctaaaaacgc tgatttcaat ttattcgact cttccgcctt atccctagcc attcgaaggt
     7741 catgttccaa ttgcttacgc tcggtaatag atatcgtaga cccgatcaac gctttcggtt
     7801 taccggaagc atcatattca gccattacct gtatctcctc ccactcatgg cgatcttctc
     7861 ccggaatcaa ccgctccaga caatattctt ttcgtacttt ctttattttc ccattacaca
     7921 aatcatcgaa agccttttcc acgcaagccc tgaaagacgg gtgtatcttg ctgaaatatt
     7981 ccttcaacga aacctcatgg gtatgcacct ctgctgtctc tatattatct cccggatgta
     8041 ctttcgactc atagataatc ttcccttcag ccagattata tcgccacggt aaaagatctg
     8101 ccgcctctaa cgccatagcc agcttatgat tcatggcttt caaatgcgtc tggaatttat
     8161 ggatatccgt aatatcaata aaaaacgcgt caactacatt ctcttccgag gtaggcatga
     8221 tgataatcgt atagtaaagc cctgtcggct caaaataata ctcataagtg aaggattttc
     8281 cactctctaa aaccgtaggc actgccgata ggagcaaagg ataactcccg ccaatcaaat
     8341 ttgcgatctc ttttccacgc ttatttacca caaaatcttt aggagcgatt ttctcctcga
     8401 aagcatggtt cacatctaaa acctgcacat cgatttgcga accttcccga atcagccgct
     8461 gccgtatata aggtaacggc atattattaa ataaatcacg gtaacgggac aacaacctca
     8521 actctacttc cttcatcttt tgtttagaac gatacacata atgccccgct aaaaacacta
     8581 ctaccagaaa gaatattaga aagcctaaca gctgcatcca atatttttcc aagaaagagg
     8641 gaggcgcatt caagtagatc gcatcacgcg ggaaattatc ttcattagat atcgcactta
     8701 tcaacgaagc ataattcaag tatttatgag gatcatttac cgtcgaaacc gggatcttgc
     8761 ccatatcttc accgttataa acttgctgta gcaagggaat tagagcagtc tcaatcgttt
     8821 tagcgctatt ataatatcca ccaatcgtat atccttcttc cacgcccata tcatataaag
     8881 aaaaaacagg atgcctagaa ataccgttta taccttgata caaagtacta tataataacg
     8941 agtgattcaa gaaaggtttc tcggtaatcc acgagtaata catcacggcc gtcgctcgat
     9001 gtgggtcttt ctccgacaga accgccatta aactatccat ggagcaagaa ccctccgtat
     9061 aaaaatccac tttcccctca gggaaagaag tttccatatg tttctccatc tcatcccgga
     9121 gccatgtgga aacataacgt ctgtcggata tgaaaatcag acgtttcaaa cccgggatta
     9181 attccttcac caagtcgatc gaacctttaa cataataagg gataaccaat cccgtagcgt
     9241 tatacccctt aaccgcctct tgtaaaggaa tcaccctatc agaggaatgc cgctgattaa
     9301 aataacattc atcttctgcc atttcacccg tttccgaaca gaccagagtg ggaatatccc
     9361 cccatttctc ccggatctta tcccgcataa aagcccatcc atttacgcct aagtagataa
     9421 ttccatccgg cttcttctta ttaacttcaa agaaggcctc ttgcttctct tttaatttct
     9481 ctggcgtatc aaccaacatc acgctcatat gatctatccg gagggtgtac tcctccgggg
     9541 tagcgaactt cgagatcatg tttaataaat taccagacca gcgttcgcca tccacatatg
     9601 aatttattac caatacatac gattcatcct tgaccggata tgaaaaactc ccataagccg
     9661 gagtcggcat accggctatc aagcataaaa tcaatccaaa ataaagtatt attgccttta
     9721 aatttataat atttcgtatc attccctaca ttcctctatt gcagttgtaa agacaaagat
     9781 attccttaat tatcaactaa tcttatcaaa ctagtttttt tatcaagttt tggtgtcaaa
     9841 ttcacgtttc ttacaaacta aaggcttttt taatcgggat tattcggtta tttaccgata
     9901 ctcgtataga aatcagcggt atttacttgt gtatagaatg acgaacccgt acatttgata
     9961 aaaaacaaaa aatggaactt atggatatga aagattatga catcgatttt aaagagaaga
    10021 ggacaaacgg gtatctgatc gctaccttat ttatcattgt cggtatatta tttttactgc
    10081 ggaatctagg aatgatagat ccatccttat ttgacttgct tgtatcttgg ccgatgctgc
    10141 ttgtcgtgtc gggcatcttt acgattttcc accgtaatcc ggtaggaggt atgctcctcg
    10201 tgggcgtggg agtctatttc cttttcccgc agttaaattg gatcacgaac gatttcttac
    10261 gtgtatattg gccgttagga ttaatcctgt taggattggt catcatgctg aagcggaaag
    10321 attctatccg cacgaaaaag cataaacgtc cttttaacca tccccctttc gggcaccgaa
    10381 agcctaacga tgagatcaac tacgagacag ataacggttt cgtatcggtt gacaccactt
    10441 tcaactcggt aaggcacatc gtactggacc ccgtattcaa gggggcggac atagacgtat
    10501 ctttcggcaa cgtgattctt gatcttaaaa aaacaacatt agaggctgat gaaaccatca
    10561 taaacataga tagctccttc agcggcgtag taatatacgt tcctaaagga tggctggttc
    10621 gtctaaaggt tggttctttc ttggctggat gccaagatat gagggacctg acagaaacaa
    10681 ccgacatgac gcacacgttg tatatatgtg gagacttgtc gttcagcggc cttgaactaa
    10741 gagactaaac tcatcatgca agaacatcct attacaacat ccatattaca taaagggcag
    10801 ggaagcctat tattactttt agccatagcg atccaatgcg cattattaac tctttatggc
    10861 gatcttccgt tgagcatcac tttggtcgat agcttacttt ccatcgcatt gttcgccgta
    10921 gcgggatatt atctttggta tgtacaatgt acgttacata tcatgcaagc acgagtggct
    10981 ttcgccgtac tcgtacaaat cgcttgcata gccggatgct cgatcttgct acaaatattc
    11041 ggattggaag attgggagga attctcgatc acgattcctg ttcgattcct gttcggccta
    11101 atggcatgga tcattctatc ccaatggtat gccagccggg aaagaaagag tgaggcggaa
    11161 cctatcgtga gacaaatgga ggaaaagacg gcacctcccc cgactaccgt tccggaggag
    11221 attctagatc gtatatccgt aaaagacggg acacgtattc atatcatccc gataaaagag
    11281 atattctatt tgcaagcatg tggcgactat gtgaccttat tcaccacttc cggtcagcac
    11341 gtaaaggagc aaaccatgaa gtatttcgag cgaagccttc cttctccgga gttcgttcgt
    11401 atacatcgct cttatatcgt taatacggaa cagatattgc gagtagaact attcggaaaa
    11461 gaaacctatc aagtacgatt aaaggatgga acctatcttc gtgccagtag cgctggctat
    11521 aagctactca aagaacgtct ttccctttag cagtcctata aaagggacct aatcatcgtt
    11581 aaaattagaa gattttgatt gtaatatata gagttttgtg ttgtgtaaca ctttttggca
    11641 agcatcgata tgttacttaa catatattag ttgcaaaaga cttgacaaat ggtcttgacg
    11701 aacgtatctt tgcatcgtgg ttttttcata atagtattag atttaaggtt aacaaagttt
    11761 ggttagggct tgtcgtgaga caggctttaa ttgtttatag ggatttgctt ccctagattt
    11821 acatataact ataaaaaaac ggccacccct aaaaagaggc gaccgtaatt attcttaatg
    11881 aaagaaccta ctctttgaca atccttgtaa cttccaaatc aaagatcaaa gtcgtataag
    11941 gctttattat gacacttccc gaagcactcc ttccagccga accgtatccc atctgttgag
    12001 gaatccaaat ctcccaacga tctcctgggt gcatattctg taacgctgta gcaaaaccat
    12061 ctaccatatc agaaacagta agctcggcag gctctccagc ctcgaaagaa cgatcatcaa
    12121 aaacttcacc atttataaaa gagcctttat aataacattc caccttgctc gtataataaa
    12181 tcggctcctt actctcccca gtcttcaaga ccttgtaaag gataaatccg gcattacttt
    12241 gagaactcaa ttgctcgaaa cccggaacca gcatctgggc ttgaaaagcc tcctcattct
    12301 ggaccttcca aacctcatcc acctctagtg cctcatcatc atccccacaa gaggtgatca
    12361 tgagcacgca aaacaacatc aacgcgatat gccagtactt cttcattcgt ttactctatt
    12421 acctttttca ataaattctt catgctcacc ttctccgtga taatatcgtg aagcttatcg
    12481 atgcttacgc gctcttgctc catcgtgtca cggaaacgga tcgttacgca attatccttc
    12541 aaggtgtcat ggtctaccgt aatacaatac ggggtaccga tcgcatcctg acggcgataa
    12601 cgcttaccaa tagaatcctt ctcgtcgtat tggcaacgga agtcgaaacg caacatattt
    12661 ataatctcct cagctttctc gggcaggcca tctttcttca ccaatggcaa tacggccaat
    12721 ttgatcggag ccaaggctgc gggcaacttc aataccacac ggctctcgcc attcgccaac
    12781 gtctcctcgc agtaagaacc cgccatgatg ctcaagaaca cacggtctac accgatcgag
    12841 gtctcgatta catacggagt gtaactctgg ttcaactccg gatcgaaata ttggatcttt
    12901 ttaccggaaa acttctcatg ctgactcaag tcgaagttcg tacggctatg tataccctcc
    12961 acttccttaa atccgaacgg catttcaaac tcgatatccg tagccgcgtt agcgtagtga
    13021 gccaatttct catgatcgtg atagcgatac ttctcatcgc ccaaacctag ggcttgatgc
    13081 catttcaaac gagtagactt ccatttctta aaccactcga tctcctcacc cggacgaacg
    13141 aagaattgca tctccatttg ctcgaactca cgcatacgga agataaactg acgagccacg
    13201 atctcgttac ggaacgcctt accgatctga gcgataccga acgggatctt catacggcca
    13261 gtcttctgca cattcaagaa gttcacgaaa ataccttggg ccgtctccgg acgaagataa
    13321 atcttagtcg ctccatcagc ggtagaaccc atatccgtag agaacatcaa gttaaactgg
    13381 cgaacctccg tccagttacg agttccggaa atcgggcaaa cgatctcgca atccaagatc
    13441 aattggcgaa gatcctcgaa gtttgactcg ttcatcgcct tgctataacg ctcatggat
//
