LOCUS       c00137_gnlPro..        11024 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|IFBPMIFA_137.
ACCESSION   c00137_gnlPro..
VERSION     c00137_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-05 15:47:13
            Original ID  :: gnl|Prokka|IFBPMIFA_137
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 11024
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             1..2226
                     /locus_tag="ctg137_1"
                     /transl_table=11
                     /translation="TSPGDSVAVIFSCLGYNKSERILPSLQQDMRLNVQMNYTSIDLGE
                     VVAVGTRYQTSTLQTMNADRVKLLPDPAGGSIESLVVTFAGVSSSNELSSQYSVRGGSY
                     DENIVYVNGLEVFRPLLIRSGQQEGLSFINPDLTEAVNFAAGGFEARYGDKMSSVLDIT
                     YKKPKLFEGSASASLLGANAYVGSSIGKFTQITGVRYKTGRSLLKTMDTDAEYQPDFVD
                     LQSYMTYQLAPKWEVNFLGNLASNTFKFTPHKRETNFGTVENAQRFEVYFPNSRERDKF
                     QTIFGALTLKHNPNEKTELGLQASAFSSKEIETYDITGEYWLGDATTENDNNQNALEIA
                     RYHEHARNRLSSTIMNVGHYGSSKIKNNTLKWGATVQMEKINDRISEWEKRDSAGYSLP
                     QTGNGVNVISNLYSDNDLSTTRISGYLQDVFKFRTKQGMFTLIGGIRGSYWSYNKEFIF
                     SPRVSLGFIPNFDQNLTFRAATGIYYQSPFYKELRTTVQDAAGNDIIELNKDIKSQRSI
                     HFILGGDYTFRAADRNFKVSADLYYKKLDDLIPYTVDNVKIRYYGENCAKGHAMGIDVK
                     FFGEFVPGTDSWISFSLMKAEQTIRDMVTVPMPNSQGYNVSLFFQDYFPGYKRVKLNLK
                     GVLSGGLPFIAPRTKYEDVKSTFRTPAYKRVDLGFSYQLAGGTDAIMDRGVFRHLKNIW
                     IGVDVFNLFDIKNVSSYYWITNIDNQQYAVPNYLTGRQLNARLIVDF"
     protocluster    1..11024
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[2426:6946]"
                     /cutoff="10000"
                     /detection_rule="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /neighbourhood="10000"
                     /product="succinate2propionate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      2427..6946
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /neighbourhood="10000"
                     /product="succinate2propionate"
                     /protocluster_number="1"
     cand_cluster    1..11024
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /kind="single"
                     /product="succinate2propionate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..11024
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="succinate2propionate"
                     /region_number="1"
                     /rules="(minimum(4, [AcetylCoA_hyd_C, AcetylCoA_hydro,
                     B12-binding, Biotin_lipoyl, Glyoxalase_4, HMGL-like,
                     MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma, PYC_OADA]) and
                     minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /tool="gutsmash"
     CDS             2427..2828
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: Glyoxalase_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg137_2"
                     /sec_met_domain="Glyoxalase_4 (E-value: 4.8e-28, bitscore:
                     87.0, seeds: 51, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEITHIEHLGIAVKSIEACLPYYEEILGMKCYNIEEVADQKVKTA
                     FFKVGQTKIELLEPTSEDSKFIEKKGEGIHHIAFAVPDVQAALDEAESKGVKLIDKAPR
                     GGAEGLNIAFLHPKSTCSVLTELCMPGKK"
     CDS             2866..4419
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: CT_Btheta"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg137_3"
                     /sec_met_domain="CT_Btheta (E-value: 7.5e-293, bitscore:
                     960.5, seeds: 72, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSNQLEKVKELIALREQARLGGGEKRIESQHKKGKYTARERIAML
                     LDEGSFEEFDMFVQHRCTNFGIEKTKFLGDGIVTGYGTIDGRLVYIFAQDFTVFGGALS
                     ESLAMKICKVMDQAMKMGAPVIGLNDSGGARIQEGVNALAGYAEIFQRNILASGVVPQI
                     SGIFGPCAGGAVYSPALTDFNIMTRGTSYMFLTGPKVVKTVTGEDVTQEQLGGASVHTT
                     KSGVAHFAVDTEEEGLQLIRKLLSFLPQNNLEETPLIECKDPIDRLDDVLNDIIPDNAN
                     QSYDMYEVIGTIVDNNEFLEVHADYAKNIIVGFARFNGQSVGIVANQPKVMAGCLDSNA
                     SRKAGRFVRFCDAFNIPLVTLVDVPGFLPGTGQEYNGVILHGAKLLYAYGEATVPKITV
                     TLRKSYGGAYCVMSSKHLRGDMNYAWPTAEIAVMGPSGAVEVIFAKEVAASEDPAKATA
                     EKEAEYKKAFANPYNAAQYGYIDDVIEPRNTRFRIIRALQQLQTKKLSNPAKKHDNLPL
                     "
     CDS             4442..5326
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: OAD_gamma"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg137_4"
                     /sec_met_domain="OAD_gamma (E-value: 1.2e-12, bitscore:
                     37.7, seeds: 234, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTNKRFGVLLLFILLVSFGAQAQRATSMRINEVLVINEDNFVDDY
                     GKRHGWIELFNTSAGTVNIAGCFLTDDKNNPKKYPIPKGDVLTQIPPHQHTLFWADGEP
                     NRGTFHVNFTLDPSKENYIALYDADGKSLIDEITIPAAQKPDVSYGRIIDGKEEWAQLT
                     KVTPSTNNLTLDSNEKIENFKTNDSLGIGMTITAMAVVFLGLLLLFLIFKQVGKAAIAA
                     SKRNAQKAGAPVNVNTPDEVSGEVFAAIATALYEMSDDNHDIEHTVLTIRKVRRAYSPW
                     SSKIYSLRETPRK"
     CDS             5350..5781
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: Biotin_lipoyl"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1024:Biotin-requiring enzyme (Score: 63.9; E-value:
                     3e-20)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg137_5"
                     /sec_met_domain="Biotin_lipoyl (E-value: 4.3e-21, bitscore:
                     63.9, seeds: 40, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKSFKYTINGNVYKVHINSVVDDIAEVEVNGTPYNVKMEKPAKKQ
                     MVTLKRPAQAPTTASGEPVVTRPAASTTQGAVKTPLPGVILQIKCNVGDTVKRGQTLLI
                     LEAMKMENNINADRDGKIIEIKVHKGDSVLEGADLVVIG"
     CDS             5786..6946
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: OAD_beta"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg137_6"
                     /sec_met_domain="OAD_beta (E-value: 3.2e-154, bitscore:
                     502.3, seeds: 229, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQESFLSFLGDNLQLFLTYTGVYNATPGHIIMILVGLLFIFLAIK
                     YEFEPMLLIPIGFGILIGNIPFKDAGLQVGIYEQGSVLNILYQGVTSGWYPPLIFLGIG
                     AMTDFSALISNPKLMLIGAAAQFGIFGAYIIALQMGFEPNQAGAIGIIGGADGPTAIFL
                     SSKLAPNLMGAIAVSAYSYMALVPIIQPPFMRLLTTKKERLIRMKPPRAVSSTEKIIFP
                     IVGLLLTCFLVPSGLPLLGMLFFGNLLKESGVTRRLAETARGPLIDTITILLGITVGAS
                     TQATQFLTLNSIKIFGLGALSFVIATCAGVLFVKFFNLFLKQGNKINPLIGNAGVSAVP
                     DSARISQVVGLEYDPTNYLLMHAMGPNVAGVIGSAVAAGILLGFLG"
     CDS             7450..9192
                     /locus_tag="ctg137_7"
                     /transl_table=11
                     /translation="MSQVKGIPYGISDFKRLRNENFYYVDKTMYLPLIEKMPSYLFLIR
                     PRRFGKSLFLSLMRTYYDILQKDNFEKYFGDLWIGSHPTDQRNRFQVLYFDFSKAGCSQ
                     PGTDMMTSFNDYCGLIINQFAHEYASYYDADYKATIENIASAKAKLSYIEIKAKEKGYP
                     LYLIVDEYDNFTNVILSEHGQKMFHDLTHASGFYREYFKQFKGMFDRIFLMGVSPITLD
                     DLSSGYNIDWNISTDETFNAMMGFDETDVREMFHYYRQNDMLTGDIDTMIAEMKPWYNN
                     YCFARMALDSDRVFNCDMILYYLHNQVNFHRAPEEMVDKNICINYSKLKKLTGINHKSL
                     HEDSCMNTIKDIVAKGEVLVDLHTSFPAEKVMDIDNFRSLLYYYGLLTMCGTHGKLLKM
                     CIPNNCVREQYFGFLRDYYQQFHTINLSHLKDLIDDFAYDGQWKPFFESIALAYRENSS
                     VRDAMEGERNLQGFLKAYLALASYYLVEPELEMNYGYCDFFLLPDKKRYPDIGHSYILE
                     LKYAGRTTTDTELETQAEEGRRQLLQYSKDKIALQLAQDTTLHLILLQFRGWDLVKCEE
                     IASC"
     CDS             complement(9227..10006)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_M22"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg137_8"
                     /sec_met_domain="Peptidase_M22 (E-value: 2.3e-26, bitscore:
                     82.3, seeds: 111, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LRPINPVDEQRSSIEKYLSLVNRQLSTIMSCILNIETSTSVCSVA
                     LSADGEVLFEKSSFEGPSHAALLGVYVEEAIAVTKEKGLKLDAVAVSSGPGSYTGLRIG
                     VSVAKGLCFGYGIPLISIPTLEVLAVAALEQQNNASDCLYCAMLDARRMEVYAAIYDVN
                     LKTVRETSADIVDAETYASWLEKGKVCFFGNGAAKCREVITSPNALFIDNIHPLAVNMI
                     TLSEKAFAGSRFEDVAYFEPFYLKEFQATIAKNKVLG"
     CDS             10146..11006
                     /locus_tag="ctg137_9"
                     /transl_table=11
                     /translation="MTGFGKVTAELPSKKVTVEIKALNSKQLDLSTRIPSIYKDKEMQI
                     RSQLLQSLERGKVDFSIYIEYIGKDTPTQINLTAFESYYSQVKDIAEKLNIALPADWFQ
                     TLLKMPDVIKSEIVEVDESEWEVVFNAVKGAIKHLCDFRIQEGAMLQKLFEDKIGNIAR
                     LLTEVEEYEGERIEKIKARIMDNLEKVANQDYDKNRFEQEMIYYIEKLDVNEEKNRLDN
                     HLKYFISTMKDGHGQGKKLGFIAQEMGREINTLGSKSNHAEMQKIVVQMKDELEQIKEQ
                     VLNVL"
ORIGIN
        1 acgtcgccgg gcgattccgt agcggttatt ttctcttgtc tgggatataa taagtcagaa
       61 cgtattctac ccagtttgca acaggacatg cggctgaatg tacagatgaa ctacacaagt
      121 atcgacctgg gagaagttgt tgctgtaggt acccgttacc aaaccagtac ccttcaaacc
      181 atgaatgcag accgtgtcaa gctcctcccc gaccctgccg gcggaagcat cgaaagtctc
      241 gtggtcactt ttgccggagt ttcatccagc aacgaattaa gttcccagta ttcggttcgc
      301 ggcggtagtt acgatgaaaa catagtatat gtaaacggcc tggaagtatt ccgcccgtta
      361 ctgatccgtt ccggccagca ggaaggtctg agctttatca atcccgacct gaccgaagcg
      421 gtcaacttcg cagccggagg atttgaagca cggtatggag ataaaatgag ctctgttctt
      481 gacatcacct ataaaaaacc caagttattt gaaggatcgg cctccgccag cttactggga
      541 gcaaacgcct atgtgggcag ttccatcggc aagttcacac aaataaccgg tgttcgttat
      601 aagacaggac gttcgctact aaaaacaatg gatacggacg ccgaatacca gccggatttc
      661 gtcgatctgc aatcatacat gacttatcag ttagctccga aatgggaagt aaactttctg
      721 gggaacctgg cgtccaacac gttcaaattc accccgcata aacgggagac aaacttcggt
      781 acggtagaaa acgcccaacg gtttgaagtg tatttcccca acagccgcga gcgggataag
      841 ttccagacaa tcttcggcgc actgaccttg aaacacaatc cgaacgagaa aacagaactg
      901 ggcctccagg catccgcttt ctccagcaag gaaatagaaa cctatgacat caccggcgaa
      961 tactggctgg gcgatgctac aacagaaaac gacaataacc agaatgccct tgaaatagcc
     1021 cgctaccatg agcatgcccg caaccgttta agttcaacca tcatgaatgt gggacattac
     1081 ggcagtagca agatcaaaaa caacacgctg aaatggggag ccaccgtaca gatggaaaag
     1141 ataaacgacc gcatcagcga atgggaaaaa cgcgactcgg caggttactc acttcctcaa
     1201 acagggaacg gggtaaacgt gatctccaat ctttattcgg acaatgattt gtcgactacc
     1261 cggatatcgg gatatttgca ggacgttttc aagttccgta ccaagcaagg tatgttcaca
     1321 ctcatcggcg gtatccgcgg aagctactgg agctataaca aagaattcat tttcagccca
     1381 cgcgtttctt taggttttat ccctaatttc gatcagaatc tgacctttcg tgcagcgaca
     1441 ggtatctact accagtcacc gttctataaa gaattacgaa ccaccgtgca ggatgccgca
     1501 ggcaatgata ttatcgaact gaacaaggat atcaaatcgc aacgttccat ccatttcatt
     1561 ctcggtggcg attatacgtt ccgggcagcc gaccgtaact ttaaagtcag tgccgacctc
     1621 tattacaaga aactggacga cctgattcct tacaccgtcg acaacgtaaa gatccggtac
     1681 tacggagaga actgtgccaa aggccatgca atgggtatcg atgttaaatt cttcggtgaa
     1741 tttgtacccg gaaccgattc atggatcagc ttctcgctta tgaaagcaga gcaaacaatc
     1801 cgtgacatgg taaccgttcc catgcccaac agccagggat ataacgtatc gttattcttt
     1861 caggattatt ttcccggata caaacgtgta aaactgaatc tgaaaggcgt cctctccggc
     1921 ggacttcctt ttattgcacc acgcacgaaa tacgaagatg tgaagagtac tttccgcacg
     1981 ccggcctaca aacgtgtcga cctcggtttc tcttaccagc tggccggagg aaccgatgcg
     2041 atcatggacc gcggagtctt tcgtcacctg aaaaatatct ggatcggagt ggacgtattt
     2101 aacctgttcg atataaaaaa tgtcagttcc tattactgga tcaccaacat cgacaaccag
     2161 caatatgctg taccgaatta cctgacaggc cgacaactca atgcacgact gattgtcgat
     2221 ttctaaaaat atgccaataa gataatttgc caatatgccg ataaaaaaca ggatttgcca
     2281 atgagaagtc aaggctttca ttggcaattt tgcatattgg caaattggca aattattatt
     2341 aatgaaatat ttcttgattc ttcaaaaaga atgtaccttt gccatcaaaa caaaaagcat
     2401 ttatcaatta ttaaattctt attgacatgg aaattacaca tattgaacat ctgggaattg
     2461 cagtaaaaag catcgaagct tgtctgccgt attatgaaga aattttaggc atgaaatgct
     2521 acaacatcga agaagttgct gaccaaaaag taaagactgc gttctttaaa gtaggccaaa
     2581 caaaaatcga attacttgaa ccgaccagcg aagacagcaa attcatcgaa aagaaaggcg
     2641 aaggtattca ccatatcgca tttgctgtac ctgatgtaca ggctgcattg gacgaagctg
     2701 aatcaaaagg tgtcaaactg atcgacaaag ctccccgcgg tggtgcagaa ggtctgaaca
     2761 ttgcattcct tcacccgaaa tcaacttgca gcgtattgac tgaactttgc atgccgggta
     2821 aaaaataatt aatcagttca tttctaacaa caaatcagaa atacaatgag taaccaactt
     2881 gaaaaagtaa aagagcttat cgctcttcgc gaacaagccc gtttaggtgg tggagaaaaa
     2941 agaatcgaat ctcagcacaa gaaaggcaag tacacagcac gcgaacgtat cgccatgttg
     3001 cttgacgaag gtagtttcga ggagtttgat atgttcgttc agcaccgttg tactaacttc
     3061 ggtattgaaa aaacaaaatt cctgggtgat ggtatcgtaa ccggatatgg tacgatcgac
     3121 ggccgtttgg tctacatctt cgcacaggac ttcaccgtat tcggaggagc tttgtcagaa
     3181 tcactggcca tgaagatttg taaggtaatg gatcaggcca tgaagatggg tgcccctgtc
     3241 atcggcttga acgactcagg tggagcacgt atccaggaag gcgttaacgc tctggcagga
     3301 tatgctgaaa tcttccagcg taatatcctt gcatccggtg ttgtacctca gatttcaggt
     3361 atcttcggtc cgtgtgcagg tggcgcagtt tattctccgg cgctgactga ctttaacatc
     3421 atgacacgtg gtaccagcta catgttcctg acaggtccga aagtagtaaa aaccgttacc
     3481 ggtgaagacg taactcagga acaactgggt ggcgcaagcg tacacacaac caaatcgggt
     3541 gttgcccatt tcgctgtcga cacagaagaa gaaggtctgc aactgatccg caaattgctc
     3601 agcttccttc cgcagaacaa cctggaagaa actccgctga tcgaatgcaa agacccgatc
     3661 gaccgtctgg acgatgtatt gaacgacatc attcctgaca acgctaacca gtcatatgac
     3721 atgtatgaag taatcggcac aatcgttgac aacaacgaat tcctggaagt acatgctgat
     3781 tatgctaaaa atattattgt tggtttcgca cgtttcaacg gccagtctgt tggtatcgta
     3841 gctaaccagc cgaaagtaat ggcaggctgt ctggacagca acgcttcccg taaggcaggc
     3901 cgcttcgttc gcttctgcga cgctttcaac attcctttgg taacattggt agacgtaccg
     3961 ggattccttc cgggaacagg ccaggaatac aatggtgtaa tccttcacgg agccaaattg
     4021 ctttacgctt acggcgaagc aactgtgcct aaaatcactg ttacattgcg taaatcttac
     4081 ggtggtgctt actgcgtgat gagttctaaa cacctgcgtg gcgatatgaa ctacgcatgg
     4141 ccgacagcag aaatcgcagt tatgggcccg agcggtgctg tagaagttat cttcgcaaaa
     4201 gaagttgccg catccgaaga tcctgcaaaa gcaacagccg aaaaagaagc agaatacaag
     4261 aaagcattcg caaacccgta caacgcagct caatacggtt atatcgacga tgtgatcgaa
     4321 ccgcgtaata cccgtttccg tatcattcgt gctttacaac aattgcagac gaaaaagtta
     4381 agcaatcctg ctaagaaaca tgacaatctg cctctataat tcttaaaaca ggaaaatgaa
     4441 tatgactaac aaaagatttg gagtattgct gctgttcatc ctgctcgtat cattcggggc
     4501 acaggcacag cgtgcaacct ccatgcgaat aaatgaagtg ctggtcatca acgaagataa
     4561 tttcgttgac gactatggca aacgtcacgg ctggatagaa ttattcaata cttctgccgg
     4621 aacggttaat attgcaggtt gtttcttgac agacgacaag aacaatccta aaaaatatcc
     4681 gatccccaag ggtgacgtac taactcagat ccccccccat caacacactc tgttctgggc
     4741 ggatggtgaa cctaaccgtg gtacttttca tgtcaatttc acgttagacc cgtcaaaaga
     4801 aaattatata gcactttatg acgccgatgg taaatccttg atcgacgaaa taacaattcc
     4861 ggctgcacaa aaaccggatg ttagctatgg tagaattatt gacggaaaag aagaatgggc
     4921 acaactcaca aaagtgactc ccagcacaaa caacctgacg ttagattcta acgaaaagat
     4981 cgaaaacttt aagacaaatg actctttggg tatcggtatg actattacag ctatggctgt
     5041 tgtttttcta ggcttgctcc ttcttttcct gatcttcaaa caagtcggaa aagcagctat
     5101 cgcagccagc aaacgtaatg ctcagaaagc aggggcacct gttaatgtaa atacaccgga
     5161 cgaagtttcg ggcgaagttt ttgcagcaat cgctacagct ttgtatgaaa tgagtgatga
     5221 caatcacgac atcgaacata cagtgcttac aatccgcaaa gttcgccgtg catattctcc
     5281 atggagttct aagatctata gtttacgtga aactcccaga aagtgattat ctctaaaaac
     5341 gaacaaagaa tgaaaagttt taaatatacc atcaacggta acgtatataa agtacacatc
     5401 aattcagtgg tcgacgatat cgctgaagta gaagtaaacg gtactcctta taatgtaaaa
     5461 atggagaaac cggcgaaaaa acaaatggtt acactcaaac gcccggcaca ggctcctact
     5521 acagccagcg gcgaaccggt tgttactcgt ccggcagcat ctacaaccca gggcgccgtt
     5581 aaaactccgc ttccaggtgt tatcctgcaa atcaaatgca atgtaggcga cactgtgaag
     5641 agaggacaaa ctttacttat cctcgaggct atgaagatgg aaaacaacat caacgctgac
     5701 cgcgacggta agattattga aattaaagta cataagggag actccgtact ggaaggtgct
     5761 gatctcgtcg taatcggata agagtatgca agagagtttt ttatcattcc tgggtgacaa
     5821 cctacagttg ttcctcacct atacaggagt atataatgca actccgggcc atatcattat
     5881 gatattggtt ggtttgctct ttatattcct tgcgattaaa tatgaatttg aacccatgtt
     5941 gctgatccct atcggattcg gtatcctgat cggtaacatt ccttttaaag atgcagggct
     6001 tcaggtaggt atctacgaac aagggtctgt acttaacatc ctctatcaag gggtaacctc
     6061 cggatggtat ccgccgttga tcttcctcgg tatcggggcg atgaccgact tctccgcttt
     6121 gatttccaat ccaaagctga tgttgatcgg tgctgccgcc cagttcggta tcttcggtgc
     6181 ttatattatc gctcttcaga tgggattcga accgaaccag gccggtgcta tcggtattat
     6241 cggtggtgct gacggtccta cggctatctt cctgtcttcc aagctggccc ctaacctgat
     6301 gggtgctatt gcggtgtcag cctactcata tatggcgttg gtacctatta tccagccgcc
     6361 gttcatgaga ctgcttacaa caaagaaaga acgtctgatc cgtatgaaac cgccgagagc
     6421 cgtttcttct acagaaaaga tcatcttccc gatcgtaggt ctgttgctga cttgcttcct
     6481 tgtaccttca ggtctgccct tgctgggtat gttgttcttc ggaaacctgt tgaaagaaag
     6541 tggtgtaacc cgtcgtctgg ctgaaacagc ccgcggtccg ctgatcgata caatcaccat
     6601 cctgttaggt atcacagtag gtgcttctac acaggcaact cagttcctga cactgaactc
     6661 tatcaagatc ttcggtttag gtgcgttgtc attcgtgatt gcaacctgtg ccggtgtatt
     6721 gttcgttaag ttcttcaacc tgttcctgaa acaaggcaac aagatcaatc cgcttatcgg
     6781 taatgccggt gtatctgccg ttcccgactc agcacgtatc tctcaggttg taggtctgga
     6841 atatgacccg accaactatc tgttgatgca cgccatgggt ccgaacgtag caggtgtaat
     6901 cggttctgct gtagcagccg gtatcctgtt aggattctta ggataataaa acaagtgaca
     6961 gttgatagat ggcaagtgac agataaatag aatcttttct aaatctgtca actgtcactt
     7021 atcaactgtc aactttttat acattttgtt cgacctccat cggatttgtt tccggattag
     7081 ttacttcttc caatgtcgtc cccacaaaca accataccat caaaaggaca atcgcaataa
     7141 taaccccgat gatcaaccat agatttttct ttttcatacc ttcgtaattc tgattttgtt
     7201 ttatatgagc ataaaacaac agaaacaagt ctttggttta aaaagatcta tgagtaaaat
     7261 acgaaaccta ctgccatact atcatagttg acaaatattc atccgattac aaatgattta
     7321 gcaccatact ctcatacgca attcatataa taatagactg taaaacacaa agctggaata
     7381 ctttctcaaa cattgtttta tttgccggaa taaactaact ttgtctctat atcttaaaaa
     7441 gtatccaaca tgagccaagt aaaaggaata ccatacggaa tatctgattt caaacggttg
     7501 agaaacgaaa acttttatta cgtagacaag acgatgtatc tgccgctgat cgaaaagatg
     7561 cccagctact tgtttcttat ccgtcccaga cgattcggaa aaagtctgtt ccttagcttg
     7621 atgcgtacct attatgatat attgcaaaag gataatttcg aaaagtattt cggcgattta
     7681 tggattggca gccacccgac cgaccagcgc aaccgctttc aggtgcttta cttcgatttc
     7741 tcaaaagccg gttgttcgca accgggaacc gatatgatga ccagcttcaa cgactattgc
     7801 ggtctgatca tcaatcagtt cgcacatgaa tatgcatcct attacgatgc cgattataaa
     7861 gctacgatcg aaaatatagc aagtgccaaa gcaaaactgt cgtacatcga gataaaagca
     7921 aaagaaaaag ggtatccgct ttatcttatc gtagacgaat atgacaactt cacaaacgtc
     7981 atactgagtg aacacggaca gaaaatgttt cacgacctaa cacatgccag cggtttctac
     8041 agggaatact ttaaacagtt caaagggatg ttcgaccgga ttttcctgat gggggtcagt
     8101 cctatcactt tggatgattt atcgagcggt tataacatcg actggaatat ctcgactgac
     8161 gaaactttta acgcaatgat gggattcgat gaaacagatg ttcgtgaaat gtttcattat
     8221 taccggcaaa acgatatgct gacaggagac atagatacaa tgatcgcaga aatgaaaccg
     8281 tggtataata attattgttt cgcacgaatg gcattggata gtgaccgggt gttcaattgt
     8341 gacatgattt tgtattattt acacaatcag gtaaatttcc accgtgcccc ggaagagatg
     8401 gtagacaaaa atatttgcat aaattacagc aaactaaaaa agctaaccgg tatcaaccat
     8461 aaaagtttac acgaagatag ctgtatgaat actatcaaag atattgtcgc aaaaggagaa
     8521 gtgctagtcg acttgcacac ctctttcccg gctgaaaaag taatggatat cgataatttc
     8581 cgaagtctac tttattacta cggactgctt actatgtgcg gtacacacgg aaaactatta
     8641 aaaatgtgta tccccaataa ttgcgtacgt gaacaatact ttggtttcct gcgcgattat
     8701 tatcaacagt ttcatacaat aaacctttct catctgaaag atttaataga cgacttcgct
     8761 tacgacggcc aatggaaacc gtttttcgaa tccatcgccc ttgcctatcg tgaaaactct
     8821 tccgtacgtg atgctatgga aggagaaaga aatctgcaag gttttctgaa ggcatatctg
     8881 gcactcgctt cttattatct ggtagaaccg gaactggaaa tgaattacgg ttactgcgat
     8941 ttctttttat tacctgacaa aaagcggtat cccgatatcg gacacagcta catattggag
     9001 ttaaagtacg ctggacgtac caccaccgac acggaactcg aaacgcaagc agaagaagga
     9061 cgccgccaac tattacaata cagtaaagac aaaatcgctt tacagttggc ccaagacaca
     9121 acacttcatt tgatactgct tcaattccgg ggttgggatt tggttaagtg tgaagaaata
     9181 gcttcctgct aacaatcttc accggatgat agctttcaaa acgctatcat cccaacacct
     9241 tattcttagc gattgttgcc tgaaattctt tcaggtagaa cggctcgaaa taagcgacat
     9301 cctcaaaccg acttccggca aatgcttttt cagacaaggt tatcatatta acagccagcg
     9361 ggtggatatt atcaataaag agcgcattcg gagaagtaat cacctcccga catttggctg
     9421 caccgttccc aaagaaacaa actttccctt tttccagcca ggaagcataa gtttctgcat
     9481 ctacaatatc agcagacgtt tcgcgaaccg tcttcaaatt aacatcatag atagctgcat
     9541 acacctccat ccgacgggca tcgagcatgg cgcaatacaa acagtcggac gcattatttt
     9601 gctgttccaa tgcggcaaca gccaacactt ccagcgtagg gatactgatc agaggtatgc
     9661 cgtaaccgaa acacaaacct ttggcgaccg atacgccgat acgcaatccg gtataagatc
     9721 ccggaccgct gctgacagct actgcatcca gcttcaatcc tttttctttg gtcaccgcaa
     9781 tagcctcttc cacataaaca cccaacaaag cagcatgcga cggaccttca aacgaactct
     9841 tttcaaaaag cacctcacca tcagccgata aagcgacgga acacaccgag gtcgatgttt
     9901 caatatttaa aatacaagac ataatagttg acagttgacg gttgacaagt gacagatatt
     9961 tttcaataga actccgctgt tcatcaaccg gattaattgg tcgcaaaagt acaaaaacgt
    10021 ctttatacga atgagaaaat aacgaacttt ttctctatca ggacgaagaa ttatcaactg
    10081 tcaactgtca actatcaact gaataagcta tctttgcaca aatttttaga acaatgatac
    10141 aatcaatgac tggattcggt aaggttacag ccgaacttcc ttcaaaaaag gtaaccgtag
    10201 aaataaaagc actcaacagc aaacaactgg atttatcaac ccgcatccct tctatctaca
    10261 aagataagga aatgcaaatc cgtagccagc tgcttcagtc gcttgaacgg ggtaaggtcg
    10321 atttcagcat ttatatcgaa tatataggaa aagatactcc tacccagatc aaccttaccg
    10381 cttttgaaag ttattacagc caggttaagg atattgcaga aaaactgaat attgcacttc
    10441 cggctgactg gttccagaca ttactaaaaa tgccggacgt tatcaaatct gaaattgtag
    10501 aagtagacga aagcgaatgg gaagttgttt tcaatgcggt aaagggagcc atcaaacatc
    10561 tttgtgactt ccgcatccag gaaggcgcca tgctgcaaaa gttatttgaa gacaaaatcg
    10621 gtaatatcgc ccgcctgctg accgaagtgg aagaatatga aggcgaacgc atcgaaaaga
    10681 tcaaagcccg tatcatggat aacctcgaaa aggtagccaa ccaggattac gacaagaacc
    10741 gcttcgagca ggaaatgatc tattacatcg aaaaactgga tgtgaacgaa gaaaagaacc
    10801 gcctcgacaa ccatctgaaa tatttcatca gcacgatgaa agacggacac ggacaaggca
    10861 aaaagctcgg tttcatcgct caggaaatgg gccgcgaaat caacacgctc ggttcgaaaa
    10921 gcaaccatgc ggaaatgcag aaaattgtcg ttcagatgaa agacgaactg gaacaaatca
    10981 aggaacaggt actaaacgta ttataatatg gctggtaaat taat
//
