LOCUS       c00080_gnlPro..        10967 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|AEBIMCOL_80.
ACCESSION   c00080_gnlPro..
VERSION     c00080_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-07 17:33:11
            Original ID  :: gnl|Prokka|AEBIMCOL_80
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 10967
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..10967
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[1081:7163]"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      1082..7163
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
     cand_cluster    1..10967
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /kind="single"
                     /product="TPP_AA_metabolism"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..10967
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="TPP_AA_metabolism"
                     /region_number="1"
                     /rules="(TPP_enzyme_C and not (PFL-like or PFL_6_pcresol or
                     PFL_9_tma or Gly_radical or Gly_430_pcre or Gly_8-9_TMA or
                     PFL_acetate1 or PFL_acetate2 or Gly_radical_scatole or
                     PFL_proline or PFL_toluene) and minimum(2, [ALS_ss_C,
                     AlaDh_PNT_C, Arginase, BKACE, BcrAD_BadFG, Beta_elim_lyase,
                     CPSase_L_D2, Cys_Met_Meta_PP, ELFV_dehydrog, GRDB,
                     Glu_syn_central, Glu_synthase, Gly_reductase, HAAA1, HG2B1,
                     HG2B2, HGD-D, HleuD1, HleuD2, HleuS1, HleuS2,
                     Homoserine_dh, ILVD_EDD, IlvC, Lactoyl-CoA1, Lactoyl-CoA2,
                     Lyase_aromatic, MAAL_C, OKR_DC_1_5_lysine,
                     OKR_DC_1_5_ornithine, OKR_DC_1_7_arginine, OKR_DC_1_C,
                     OTCace, PALP, Proline_reductase, Sacchrp_dh_C, TPL,
                     Thr_dehydrat_C, TnaA, Urocanase]) and not (POR or POR_N or
                     PFOR_II))"
                     /tool="gutsmash"
     CDS             complement(20..592)
                     /locus_tag="ctg80_1"
                     /transl_table=11
                     /translation="METVENKYITVAYKLYSIENGEKDFEEEAPVEHPFQFISGLGMTL
                     EPFEAQIKDLQIGDKFDFTIPASEAYGEYDDDHVIDLPKEIFMIEGEFDSDRVVEGAVI
                     PLMTSEGQRINGSVVEVKEDIVVMDMNHPLAGCDLNFTGEVVESRLATNEELAEVARMM
                     GGGCGSCGCGDCGDGCGDHECGGGCCH"
     CDS             1082..2884
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ILVD_EDD"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg80_2"
                     /sec_met_domain="ILVD_EDD (E-value: 2.1e-219, bitscore:
                     718.4, seeds: 918, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKHQLRSSFSTQGRRMAGARALWTANGMKKEQMGKPIIAIVNSFT
                     QFVPGHVHLHEIGQFVKEEIEKLGCFAAEFNTIAIDDGIAMGHDGMLYSLPSRDIIADS
                     VEYMVNAHKADAMVCISNCDKITPGMLMAAMRLNIPTVFVSGGPMEAGEWNGQHLDLID
                     AMIKSADESVGDKEVAQIEQHACPTCGCCSGMFTANSMNCLNEAIGLALPGNGTIVATH
                     ENRKKLFEDAARLIVENAFRYYEEGDESVLPRSIATREAFLNAMTLDIAMGGSTNTVLH
                     LLAVAHEAGADFKMDDIDMLSRKTPCLCKVAPNTQKYHVQDVNRAGGIIAIMDELAKGG
                     LVDTNVRRVDGMTLAEAIDRYSITSSNVCKEAIKKYSSAAAGKFNLVLGSQNASYKELD
                     TDRATGCIRDLEHAYSKDGGLAVLKGNIAQDGCVVKTAGVDESIWKFTGPAKVFDSQDA
                     ACDGILGGKVVSGDVVVITHEGPKGGPGMQEMLYPTSYIKSRHLGKECALITDGRFSGG
                     TSGLSIGHVSPEAAAGGNIGKIKDGDIIEIDIPNRSINVKLTDEELAARPMTPVTRNRE
                     VSKALKAYASMVSSADKGAVRLID"
     CDS             2976..4727
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg80_3"
                     /sec_met_domain="TPP_enzyme_C (E-value: 6.8e-48, bitscore:
                     151.4, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MADNNKKSNFSSLSQGEGRGEALITGAEALMRSLEHQGVKTIFGY
                     PGGSIMPVFDALYDHRKELNHILVRHEQGATHAAQGFARVSGEVGVCLVTSGPGATNTI
                     TGIADAMIDSTPIVVIAGQVGTNFLGTDAFQEVDLVGITQPITKWSYQIRRAEDVAWAV
                     ARAFYVAKSGRPGPVVLDFAKNAQVEKTEYAPTKVDYVRSYLPVPEMEPEAIRKAAELI
                     NGAKRPLVLVGQGVELGEAQQELRAFIEKAGMPAGCTLLGLSALPTNHPLNKGMLGMHG
                     NLGPNINTNKCDVLIAVGMRFDDRVTGKLETYAKQAKIIHFDIDPAEIDKNVKTDVAVL
                     GDCKETLAAVTQLLEPANHQEWIDSFRQYEEVEEEKVIRPELHPAGKALSMGEVVRAVS
                     EATHNEAILVTDVGQNQMMSARYFKYSKERSIVTSGGLGTMGFGLPAAIGATFGRPDRT
                     VCVFMGDGGLQMNLQELGTIMEQKAPVKMILLNNNFLGNVRQWQAMFFNRRYSFTPMMN
                     PDYMKIASAYDIPARRVMTREELAKAIDEMIATDGPFLLEACVEEEGNVMPMTPPGGSV
                     NQMLLEC"
     CDS             4760..5320
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ALS_ss_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg80_4"
                     /sec_met_domain="ALS_ss_C (E-value: 4.8e-20, bitscore:
                     60.8, seeds: 685, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDKKLYTIIVHSENFAGLLNQVTAVFTRRQINIESLNVSASSIKG
                     VHKYTITAWTDKDTIEKVTKQITKKIDVLQAHYFTDDEIYQHEIALYKITTPTLEEKPE
                     VSKVIRKYNARIVEVNAVFAIVEKNGMSEEITNLYEELRQLDCVLQFVRSGRVAITTSC
                     FERVNEYLADREAKYRQSKHQES"
     CDS             5317..6069
                     /locus_tag="ctg80_5"
                     /transl_table=11
                     /translation="MMSENNKIGTYKFVAEPFHVDFTGRLTMGVLGNHLLNCAGFHASD
                     RGFGIATLNEDNYTWVLSRLAVELDEMPYQYEDFSIQTWVENVYRLFTDRNFAIIDKEG
                     KKIGYARSVWAMISMNTRKPADLLALHSGSIVDYVCDEPCPIEKPSRIKVASKEPVAAL
                     VAKYSDIDINGHVNSIRYIEHILDLFPIEMYKEKRIRRFEMAYVAESYYGDELTLFMDD
                     AGEGVYDVEVKKNGSEVVCRSKVIFTEK"
     CDS             6120..7163
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: IlvC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) IlvN"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg80_6"
                     /sec_met_domain="IlvN (E-value: 3.1e-47, bitscore: 149.3,
                     seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="IlvC (E-value: 2.8e-41, bitscore: 130.3,
                     seeds: 295, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAQLNFGGVIENVMTREEFPLEKAREILKDETIAVIGYGVQGPGQ
                     ACNLRDNGFNVIVGQRPGKTYEKAVADGWVPGETLFGIEEACQKGTIVMCLLSDAAVMS
                     VWPTIKPYLTPGKALYFSHGFAITWNDRTGVVPPKDIDVIMVAPKGSGTSLRTMFLEGR
                     GLNSSYAVYQDATGKAFDKTIALGIGIGSGYLFETTFIREATSDLTGERGSLMGAIQGL
                     LLAQYEVLRENGHTPSEAFNETVEELTQSLMPLFAKNGMDWMYANCSTTAQRGALDWMT
                     PFHDAIKPVVQKLYASVKSGNEAQISIDSNSKPDYREKLNAELKALRESEMWQTAVTVR
                     KLRPENN"
     CDS             complement(7225..9138)
                     /locus_tag="ctg80_7"
                     /transl_table=11
                     /translation="MITFATMKEQDSNSPIIHLQQQQVLLRMEYEYEKEEFKRQTENMG
                     VARKVKRGLCWYPATPGRSYYNSLNQLVIEITHTENTDIEHNFEFGRPVCFFRQSADGK
                     ITYMNFTATVSYADETRMVAIMPGAGAVMEVQETDNLGVQLYFDETSYRTMFEALEDTL
                     RSKGNRLAELRDILLGTSKAGFRELYPVRFPWLNSTQETAVNKVLCARDVAIVHGPPGT
                     GKTTTLVEAIYETLHREPQVLVCAQSNTAVDWISEKLVDRGVNVLRIGNPTRVNDKMLS
                     FTYERRFENHPLYPELWSIRKNLRELGSRARRGSYDEREGVRSRMSRLRDRATALEIQI
                     NAELFDGAHVIASTLVSSNHRLLNGRRFGTLFIDEAAQALEAACWIAIRKADRVVLAGD
                     HCQLPPTIKCYEAARGGLERTLMEKVVSNKPAVVSLLKVQYRMHEEIMKFPSQWFYNGE
                     LEAAPEVRYRGILDWDTPIHWIDTSEMDFKEEFVGETFGRINKAEADLLLSELKIYINR
                     IGGNRILEEKIDIGIISPYKAQVQYLRSKIKADASLKPYRSLFTVNTVDGFQGQERDVI
                     FISLVRANEEGQIGFLNDLRRMNVAITRARMKLVILGEAETLKHHGFYRKLLEFIQNIG
                     NQ"
     CDS             9253..10965
                     /locus_tag="ctg80_8"
                     /transl_table=11
                     /translation="MVYDLTMLKTFYAAYSEKIERVRNVLRRPMTLAEKILYAHLYDGD
                     KVKNYRRGEDYVNFRPDRVAMQDATAQMALLQFMNAGREQVAVPSTVHCDHLIQAYKGA
                     KEDVATATKTNEEVYNFLRDVSSRYGIGFWQPGAGIIHQVVLENYAFPGGMMVGTDSHT
                     PNAGGLGMVAIGVGGADAVDVMTGMEWELKMPRLIGVHLKGKLSGWVAPKDVILKLAGI
                     LTVKGGTNAIIEYFGPGTASLSATGKATICNMGAEVGATTSLFPYDERMGTYLKATGRE
                     EVAKMAASVAADLRADDEVLANPEKYYDRIIEIDLSLLEPYINGPFTPDAATPISKFAE
                     VVITNNYPRRMEVGLIGSCTNSSYQDLSRAASLARQVKEKNLKVASSLIVNPGSEQIRA
                     TAERDGMIAAFEDIGATIMANACGPCIGQWKRHTDDPERKNSIVTSFNRNFAKRADGNP
                     NTFAYVASPEITMALTIAGDLCFDPLRDTLVNAKGEVVKLSEPVGEELPAHGFIGGKEG
                     YIAPGKGQTEITVNPHSQRLQLLTPFPAWDGMDLLDMPLLIKVQGKCTTDHISM"
ORIGIN
        1 ttctttaatt tttaattctt tagtggcagc atccgcctcc acattcatgg tcgccgcatc
       61 cgtcgccaca gtcaccacaa ccgcagctgc cgcaaccgcc acccatcata cgggcgactt
      121 cggcaagttc ttcgtttgta gccaggcggc tttccactac ttctccagtg aagttcaagt
      181 cacaacctgc gagcggatgg ttcatatcca ttacgacgat atcttccttc acttctacca
      241 cacttccgtt gatgcgttga ccttcagaag tcatcaaggg gataacggca ccttctacta
      301 cacgatcgct gtcgaattct ccttctatca tgaagatttc tttggggagg tcaataacat
      361 ggtcgtcgtc atattcacca taagcttctg atgccggaat ggtaaagtcg aatttatcgc
      421 ctatctgcaa gtcttttatc tgggcttcaa aaggttcgag tgtcattccc agacctgaga
      481 taaactggaa aggatgctct acgggtgctt cttcttcgaa atctttttct ccgttttcga
      541 ttgagtacag cttatatgct acggtgatgt acttgttttc tactgtttcc attaattttc
      601 tatctttatt taattagtaa atactttttt ttgagtattt gaagagacaa agatacgaat
      661 tatttgtttc gggatgtaga gagcctttgg taattttcag attattaaat ggtttcaatg
      721 attggcaata catttacatt ggctgtctga atggttctat ttagaactgt taagtgataa
      781 aataggattt tagggcgatt ttttcttacg attattcata tttatcttat ttttttcttc
      841 aatttgtttg gagattataa aaaagccctt acctttgcag cacgtttgaa acaaaaaaga
      901 agaattaagt tatgaattta catacatcta ttaacctggc agtcctgcat attattcgcg
      961 tcgtggtggt ggcatcaaga gcgtgagaaa ggttatgtat gtattcgtac gttagaagat
     1021 aatttattaa gcctttctca ctatagtggg agaggctttt tcattaaaag gagatttgaa
     1081 aatgaagcat cagttacgca gctcgttcag cacacaaggt cgccgcatgg cgggagcccg
     1141 tgcattgtgg acggcgaatg gtatgaagaa ggaacagatg ggtaagccca ttatcgctat
     1201 agtcaattca tttacacaat tcgtccccgg gcatgtacac ctgcacgaaa taggccagtt
     1261 tgtaaaggaa gagattgaaa aactggggtg ttttgctgcg gagttcaata cgattgccat
     1321 tgacgacggt atcgctatgg gacacgacgg tatgctttat tccctgcctt caagagatat
     1381 cattgccgat agtgtggagt atatggtaaa tgcccataag gcggatgcta tggtttgcat
     1441 cagtaactgt gacaagatta ctccggggat gctgatggcg gctatgaggc tgaatatacc
     1501 gactgtgttt gtttcaggcg gtccgatgga agccggggaa tggaacggac agcatttgga
     1561 tttgattgat gccatgatta aatctgctga tgaaagtgtg ggcgataaag aggtggcaca
     1621 gattgagcaa catgcctgcc ccacttgcgg atgctgctca ggcatgttta ccgctaattc
     1681 catgaattgc ctgaatgaag cgattggatt ggcactgccc ggtaacggca cgattgtagc
     1741 cactcacgaa aatcgcaaga aactatttga ggatgcagcc aggttgattg tagagaatgc
     1801 ctttagatat tatgaagaag gggatgagag tgtactcccg cgcagtattg ctactcgcga
     1861 ggcatttttg aatgccatga cgctggatat tgcgatgggc ggttccacta atacagtact
     1921 tcatttgttg gctgtggctc acgaagccgg agcggatttt aagatggacg acattgacat
     1981 gctctctcgc aagaccccct gcttatgcaa ggtagctccc aatacccaaa agtatcatgt
     2041 acaagacgtt aaccgtgccg gtggcatcat tgccatcatg gatgagcttg ccaagggcgg
     2101 attggtcgat acgaatgtcc gccgtgtgga tggaatgacg ttggcagagg caatcgaccg
     2161 gtatagtatt accagctcta atgtatgtaa agaggcaatc aagaaatact ccagtgcggc
     2221 agccggaaag ttcaatctgg tactcggctc acaaaatgcg tcttataagg aactcgatac
     2281 ggaccgtgcg actggttgta tccgtgattt ggaacatgca tacagcaagg atggcggtct
     2341 ggcggttttg aagggaaata tagctcagga cggttgcgtt gtcaagactg ccggtgtaga
     2401 cgagagtatc tggaaattta cggggccagc gaaagtcttc gactcacaag atgcggcttg
     2461 tgacggtatt ctgggtggaa aggtggtcag tggagacgtc gtcgtcatca ctcacgaagg
     2521 gccgaaaggt ggaccgggta tgcaagagat gctttatcct acttcttata tcaaatcccg
     2581 ccatctgggt aaggagtgtg cattgattac cgacgggcgt ttcagtggtg gtacttccgg
     2641 actaagtatc ggacatgttt ctcccgaagc ggctgccggt ggtaatatcg gcaagattaa
     2701 ggatggggac attatcgaaa ttgatatacc gaaccgttct atcaatgtga agttgacgga
     2761 tgaagagctt gcagcacgcc ctatgactcc ggtaacccgc aaccgtgaag tctccaaagc
     2821 attgaaagca tatgccagta tggtgagttc cgctgacaaa ggggctgtga ggctgattga
     2881 ttaaaagccc ccctttccga aagcgagggg aggagagaat gaaacaaatt tttcaagcta
     2941 ctattgagct tttaaatata atgaatagat aaagtatggc tgataataat aaaaagagta
     3001 acttttcctc cctctcccaa ggagagggtc ggggtgaggc tctaataaca ggcgcagaag
     3061 cattgatgcg ctctctggag catcagggag taaagactat tttcggttat ccgggaggga
     3121 gcatcatgcc ggtattcgat gccttatacg accatcggaa ggaattgaac cacatcttgg
     3181 ttcgtcatga acaaggagca acccatgcgg cacaaggctt tgcacgtgta tcaggcgagg
     3241 ttggcgtttg tctggttacc agtggaccgg gtgctaccaa tactatcacg ggcattgcag
     3301 atgccatgat tgacagtacg cctatcgttg tcattgccgg ccaggtaggg acgaacttct
     3361 tgggtacgga tgcatttcag gaagtggact tggtaggcat tactcagcct atcacgaaat
     3421 ggagttacca gattcgtcgt gcagaagatg tggcctgggc agtggcacgt gctttctatg
     3481 tggcaaagag cggacgtccg ggaccggtcg tgctggattt tgctaaaaac gcccaagtgg
     3541 agaaaacaga atatgcgcct actaaggtgg actatgtccg tagctatctt cccgttcccg
     3601 aaatggagcc ggaggccata cggaaggctg ctgaattaat aaatggtgcg aaacggcctt
     3661 tggtgctggt tggacaaggc gtggagctgg gagaagccca gcaagagctt cgtgctttca
     3721 ttgagaaagc cggaatgcct gccggatgca ctttattggg actttccgca ttacctacga
     3781 accatccgtt gaacaaagga atgcttggta tgcacggtaa cctggggccc aatatcaata
     3841 ccaataaatg tgatgtcctt atcgccgtag gcatgcgctt tgatgaccgt gtgacgggta
     3901 aattggaaac atatgccaag caggcgaaga ttatccactt tgatattgac cctgccgaaa
     3961 tagataagaa tgtaaagacc gatgttgctg tcctgggaga ttgcaaagag acactggctg
     4021 ccgttaccca attgctggaa cccgccaacc atcaggaatg gattgacagt ttccggcaat
     4081 acgaggaagt ggaagaggaa aaggtaatcc gtccggaatt acatccggca ggaaaagcgc
     4141 taagcatggg tgaggtggtg cgtgctgtga gtgaggctac ccataacgag gcgatattgg
     4201 tgactgatgt cggccagaat cagatgatgt ccgcccgtta tttcaaatac agcaaggaac
     4261 gtagcattgt tacttccggt ggcctgggta ctatgggctt cggccttccg gcagctatcg
     4321 gtgccacttt tggacgtccg gaccgcacgg tatgcgtatt catgggagac ggcggcttgc
     4381 agatgaacct gcaggaactg ggtaccatca tggaacaaaa ggctccggtg aagatgattc
     4441 tgttgaacaa taacttcttg ggcaatgttc gtcaatggca ggcgatgttc ttcaatcgtc
     4501 gttattcgtt tactccgatg atgaatccgg attatatgaa gattgcttcg gcatatgata
     4561 ttcctgcacg cagggtaatg acccgcgagg agctggcaaa agcgattgac gagatgatag
     4621 cgactgacgg accgttcctg ctcgaagctt gtgtggagga agaaggaaat gtaatgccga
     4681 tgacacctcc gggcggttcg gtcaatcaga tgttgttgga atgctgaagt catgcgaaat
     4741 taaagaattt actctatcta tggataaaaa actatataca atcattgttc attcggaaaa
     4801 ctttgccggt ttgctgaatc aggtgacggc tgtgtttacc cgccggcaga taaacatcga
     4861 gagtttgaat gtatcggcct cctccatcaa gggggtacat aaatatacca ttaccgcttg
     4921 gacggacaag gataccattg aaaaggtgac caagcagatt accaagaaaa tagatgtgct
     4981 gcaagcccat tatttcacgg atgatgaaat ctatcagcac gagattgccc tttataaaat
     5041 aacgacccct acgctggaag aaaaaccgga ggtgtccaaa gtaatccgta agtacaatgc
     5101 ccgtattgtg gaggtgaatg ctgtatttgc cattgttgag aagaatggca tgagtgagga
     5161 aataaccaat ctttatgagg agttgcgcca gttggattgc gtacttcagt tcgtccgttc
     5221 gggtcgcgta gccattacga ccagctgctt tgagcgtgtc aatgaatatc tggcggaccg
     5281 tgaagcaaaa tatcgtcaaa gtaaacacca ggaatcatga tgagcgagaa caataaaata
     5341 ggtacctaca agtttgttgc cgaaccgttt catgtcgact ttaccggacg gctgacaatg
     5401 ggagtattgg gcaaccattt gttgaattgt gcgggtttcc atgccagcga ccgcggtttt
     5461 ggcatcgcga ctctaaacga ggacaattat acttgggtat tgtcccgtct ggctgtcgaa
     5521 ctggatgaaa tgccttatca gtacgaagat ttctccattc agacttgggt ggagaatgtc
     5581 tatcgccttt ttacagaccg taatttcgct atcatcgata aggagggtaa gaagattggg
     5641 tatgcacgtt ccgtttgggc gatgattagc atgaataccc gtaagccggc agatttgctg
     5701 gctcttcata gtggcagcat tgtagattat gtttgcgatg agccttgccc gatagaaaaa
     5761 ccttcgcgga taaaggtggc ctcaaaggaa ccggttgctg ctttggtagc caaatacagt
     5821 gatattgaca ttaacgggca tgtgaacagc atccgttaca tcgagcatat ccttgatttg
     5881 ttcccgatag agatgtataa ggagaagcgc atccgtcgtt ttgaaatggc atatgtagcc
     5941 gaaagctatt atggggatga gttgactttg ttcatggatg atgccggtga gggcgtttac
     6001 gatgtggagg tgaaaaagaa tggcagcgaa gtggtctgtc gctctaaagt gatatttaca
     6061 gagaaataaa taaatttatc aacgttggcg taagccacaa ataaaaatta aaacaaaaaa
     6121 tggcacaatt gaattttggc ggtgttattg agaatgtaat gacccgcgaa gaatttcctt
     6181 tggaaaaagc acgtgagatt ttgaaagatg aaacaattgc agtaatcggt tatggcgtac
     6241 aaggcccggg ccaggcttgc aacttgcgtg ataacggttt caatgtgatt gtaggacaac
     6301 gtccgggtaa gacatacgaa aaggctgtgg ctgacggatg ggtaccgggt gagactttgt
     6361 tcggcatcga agaggcttgt cagaaaggta ctatcgtcat gtgtctgttg tctgacgcag
     6421 ctgtaatgtc tgtatggccg actatcaaac cttatttgac tcccggaaag gctctttact
     6481 tctctcatgg ttttgctatt acctggaacg accgtaccgg cgtggttcct cctaaagata
     6541 ttgatgttat tatggttgct cccaaaggtt ccggtacttc acttcgtacc atgttcctcg
     6601 agggtcgtgg cttgaactca tcatatgccg tctatcagga tgctacgggt aaggcttttg
     6661 acaagacgat tgcactgggt atcggcatcg gttcgggata tttgttcgag acaactttca
     6721 tccgcgaagc cacttccgac ttgaccggtg aacgcggttc attgatgggt gctatccagg
     6781 gattgctgtt ggctcagtat gaagtattgc gcgaaaacgg tcacactcct tctgaagcat
     6841 tcaatgaaac tgtggaagag ttgactcaat ctttgatgcc attgtttgcc aagaatggta
     6901 tggactggat gtatgccaac tgttctacta cggcacagcg tggtgcgctg gattggatga
     6961 ccccgttcca tgatgccatc aagccggttg tacagaaatt gtatgcaagt gtgaagtcgg
     7021 gcaacgaagc tcagatttct atcgacagta actccaaacc cgattatcgt gagaagctga
     7081 atgcagaatt gaaagccttg cgtgaaagcg aaatgtggca gacagctgtt acagttcgta
     7141 aacttcgtcc ggaaaacaat taatcagctt tatataaata ggtgaaatac cctcttcggt
     7201 gttaccggag ggggtatttc tttattattg attccctata ttttgaataa actccaatag
     7261 cttccggtaa aaaccgtgat gtttcagcgt ctctgcctct cccaatatca ccagcttcat
     7321 acgtgcccgg gtgatggcta cattcattct ccttaaatca ttcaggaatc ctatctgccc
     7381 ttcttcgttg gcgcggacaa ggctgatgaa gataacatcg cgctcttgcc cttggaagcc
     7441 atccaccgta tttacagtga acaagctgcg ataaggcttg agtgaagcgt ctgcctttat
     7501 cttgctgcgg agatattgca cttgtgcctt gtaaggggag atgatgccga tgtctatttt
     7561 ttcttccaga atgcggttgc caccgatacg gttgatgtag attttcagtt ctgataggag
     7621 caggtccgct tccgctttat tgatgcgtcc gaaagtctct cccacaaatt cttctttgaa
     7681 atccatttcg gaggtgtcaa tccagtggat aggggtatcc cagtccagga tgccccggta
     7741 acgcacttcg ggagcggctt ccaactcgcc attataaaac cattgggaag gaaatttcat
     7801 gatttcctcg tgcatgcggt attgtacttt cagcaaagag acaacggcag gtttgttgga
     7861 caccactttc tccatcaatg ttcgttccag acctccacgg gcagcttcgt agcattttat
     7921 agtgggcgga agttggcagt ggtcacccgc caacaccacg cggtctgctt ttcggatagc
     7981 tatccagcag gcagcttcta aggcctgggc tgcttcatca atgaaaaggg tgccgaaacg
     8041 gcgtccgttc agcagccggt gattgctgct tactagcgtg gaggctatga catgtgcccc
     8101 atcaaaaagc tctgcattga tttgtatttc caatgcggtg gcgcggtcgc gcaggcggct
     8161 catacggctg cgtactcctt cgcgttcgtc atagctgcca cggcgggcac ggctgcccag
     8221 ttcacggaga tttttccgga tgctccacag ctccggataa agcggatggt tctcgaaacg
     8281 acgctcgtag gtaaaggaaa gcatcttgtc gttgacacgg gtcggattgc cgatacgcag
     8341 gacattgacg ccacggtcca caagtttttc cgaaatccag tcgacggcag tattgctttg
     8401 ggcacatacc agtacctgcg gttcccgatg cagggtttcg tagatggctt ccactaaggt
     8461 ggtcgttttt ccggttcccg gaggaccatg tacaatggcc acgtcgcggg cacacagcac
     8521 tttgtttaca gctgtctcct gcgtggagtt cagccaggga aaccgtacgg gatagagctc
     8581 tcggaaaccg gctttcgagg ttcccagcaa tatgtcccgc aattcggcca ggcggttgcc
     8641 tttggagcgt aacgtatctt ccaaggcttc gaacatggtc cgataggatg tttcgtcgaa
     8701 ataaagttgc acgccgaggt tgtccgtttc ctgcacttcc ataacggcac cggctccggg
     8761 cattatcgct accatccgtg tctcgtcggc atagcttacg gtagcggtga agttcatata
     8821 ggttattttt ccatcagcag actggcggaa aaaacatacg ggacggccga actcaaaatt
     8881 atgttctata tcggtatttt ctgtgtgtgt aatttctatt actaattgat tcagtgaatt
     8941 atagtaactt cgtcccggag tggcaggata ccagcaaagt ccccgtttca ctttccgggc
     9001 aactcccatg ttttcggttt ggcgtttgaa ttcctctttt tcgtattcgt attccatgcg
     9061 cagcaaaact tgttgctgct ggaggtgaat aataggacta tttgaatctt gttccttcat
     9121 ggttgcaaag gtaatcattc ttcgcttccg acggaaaaaa tgctttattt tgttaaacta
     9181 ttcagccttt ttatttgttt atgatattaa tttgtaatct ttacaataat gaaaaactaa
     9241 aaaatagtgg ttatggtata tgatttaacg atgctcaaaa cgttttatgc tgcttattcg
     9301 gagaagatag aacgcgtacg gaacgtactg cggcgtccga tgactttagc ggagaaaatt
     9361 ttgtatgctc atttgtatga tggggataaa gtgaagaact acagacgggg agaagactat
     9421 gtgaatttcc gtcccgaccg tgtggccatg caggatgcaa cggctcaaat ggccttattg
     9481 caatttatga atgcaggccg tgagcaggtt gccgtgcctt ccactgtgca ttgtgaccat
     9541 ttgattcaag catataaagg tgcaaaagaa gatgttgcga ctgctacgaa gaccaacgag
     9601 gaggtctata attttctccg tgatgtttct tcccgctatg gcataggttt ttggcagccg
     9661 ggagcaggta ttattcacca ggtggtattg gagaactacg catttccggg tggaatgatg
     9721 gtaggcacgg actctcatac gcccaatgcc ggaggtttgg gcatggtggc cattggtgtg
     9781 ggtggtgccg atgcggtgga tgtgatgacc ggcatggaat gggaactgaa aatgccgcgt
     9841 ctgataggcg tacacttgaa gggtaaattg agtggctggg tagctcccaa agacgttatt
     9901 ctgaagttgg cgggtattct tactgtaaaa gggggaacca atgccatcat tgaatatttt
     9961 ggaccgggaa ccgcttcatt gtctgccact ggaaaggcta ccatctgcaa tatgggggca
    10021 gaggtggggg cgactacctc ccttttccct tacgatgagc gcatgggtac ctacttgaag
    10081 gctaccggac gtgaagaagt ggcaaaaatg gctgcttccg tagctgccga ccttcgcgcc
    10141 gacgacgaag tgctggcaaa tccggaaaaa tattacgacc gcatcattga aatagacctc
    10201 tcgctattgg aaccgtatat caacgggccc tttacgccgg atgcagcaac accgatatcg
    10261 aaatttgccg aggtagtgat aaccaataac tatccccgcc ggatggaagt cggtctgata
    10321 gggtcgtgca ccaattcgtc ctatcaggat ttgagccgcg cggcctccct tgcccggcag
    10381 gtaaaggaaa agaatttgaa ggttgcttcc tcgctgattg tcaaccccgg ctcggagcag
    10441 atacgtgcca ctgctgaacg cgacggcatg attgccgctt tcgaagatat tggcgcaacg
    10501 ataatggcga atgcctgcgg accttgtatt ggccagtgga agcgccatac tgatgacccc
    10561 gaacgcaaaa attccatcgt cacctctttt aaccgtaatt ttgccaaacg tgccgatgga
    10621 aatcccaaca cttttgctta cgtcgcttcc ccggagataa cgatggcgct gaccattgcc
    10681 ggtgaccttt gtttcgaccc gttgagggat acgctggtca atgccaaagg agaggttgtg
    10741 aaactgtccg aaccggtcgg tgaagaattg ccggcacacg ggtttatagg aggaaaggaa
    10801 ggatacattg ctccaggcaa aggacagacg gaaattacgg tcaatcctca ttcacagcgc
    10861 ttgcaactgc tgactccctt ccctgcctgg gatggcatgg atttgctgga catgccttta
    10921 ttgattaaag tacaggggaa atgtaccacc gaccacattt ccatggc
//
