LOCUS       c00042_gnlPro..        16293 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|DELKOMLB_42.
ACCESSION   c00042_gnlPro..
VERSION     c00042_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-05 16:20:20
            Original ID  :: gnl|Prokka|DELKOMLB_42
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 16293
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             1..1944
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_M22"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg42_1"
                     /sec_met_domain="Peptidase_M22 (E-value: 1.2e-09, bitscore:
                     28.2, seeds: 111, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="STNCYFSIYLFGWETLVINCTHCGPRFSIIRDLPYDRSQTTMGGF
                     LMCPDCEKEYTNVIDRRFHAQPVACNHCGPTYYATYNEETYIDYETLLKLTSRLLLGGE
                     VIAAKGIGGYHLICDASNERAVARLREIKQRDTKPFAVMFRDLEHLQVYTATEPMEERC
                     LVSWRRPIVLLRQRSRLASGINPGMHTLGCMLSYMPIHYDWFARTGIPALVMTSGNLSD
                     LPIAITPEDAEAQLAGKVAVLLHHNRPIHNRVDDSVLQVCGGQPCLIRRSRGYVPEPFF
                     TDTNVEGIMAFGAEKVNTFALGKGETILQSQYIGDLKNWETFRFYTESMERFRHLFRFN
                     PQRLVCDLHPDYLSSQEAERISKSLSLPLLKVQHHHAHAAACMLEHGLNEPVLAIVMDG
                     TGLGDDGKVWGGEFFFCDRAKYRRLSHFEYVPLPGGDKAAEEPWRMVVAYLWHYFKDEP
                     SGIPYPADFVERIGTERIAMLERMMEKGVNTPYTSSAGRLFDAVASLLGICDVSSHQAE
                     APVLLEQAAMGERNAYAYPVSAEGEEISFYSLFEALLHDKTNEVPVSLISARFHTTLAS
                     LFVQKARLLIKRTKATQVVISGGCFQNKLLTESMRRQFIMAGVPVYIPSRIPCNDGGIA
                     VGQLTIASVTPF"
     protocluster    1..16293
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[3165:9628]"
                     /cutoff="10000"
                     /detection_rule="(minimum(1, [PFOR_II, POR, POR_N]) and
                     minimum(2, [CoA_binding, CoA_binding_2, Ligase_CoA, PTAC,
                     Succ_CoA_lig]) and not (Gly_radical_scatole or Gly_radical
                     or Gly_430_pcre or Gly_8-9_TMA))"
                     /neighbourhood="10000"
                     /product="OD_unknown"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      3166..9628
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(1, [PFOR_II, POR, POR_N]) and
                     minimum(2, [CoA_binding, CoA_binding_2, Ligase_CoA, PTAC,
                     Succ_CoA_lig]) and not (Gly_radical_scatole or Gly_radical
                     or Gly_430_pcre or Gly_8-9_TMA))"
                     /neighbourhood="10000"
                     /product="OD_unknown"
                     /protocluster_number="1"
     cand_cluster    1..16293
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(minimum(1, [PFOR_II, POR, POR_N]) and
                     minimum(2, [CoA_binding, CoA_binding_2, Ligase_CoA, PTAC,
                     Succ_CoA_lig]) and not (Gly_radical_scatole or Gly_radical
                     or Gly_430_pcre or Gly_8-9_TMA))"
                     /kind="single"
                     /product="OD_unknown"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..16293
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="OD_unknown"
                     /region_number="1"
                     /rules="(minimum(1, [PFOR_II, POR, POR_N]) and minimum(2,
                     [CoA_binding, CoA_binding_2, Ligase_CoA, PTAC,
                     Succ_CoA_lig]) and not (Gly_radical_scatole or Gly_radical
                     or Gly_430_pcre or Gly_8-9_TMA))"
                     /tool="gutsmash"
     CDS             1957..2304
                     /locus_tag="ctg42_2"
                     /transl_table=11
                     /translation="MHELSIARSIVELVEEQADNRGASVVEELELEIGHLSGVEIQTLA
                     FALDSAIKGSKLEKARIIRHYIEGEGQCSDCETIFPMNALFSPCPHCGSYLVKILKGKE
                     LRVKSIVIKKE"
     CDS             2334..3086
                     /locus_tag="ctg42_3"
                     /transl_table=11
                     /translation="MCGTCGCGEHHHHHDHTHEHSHGHEHHHHPDEGIVINLEQDILQR
                     NNLLAERNRGYFEAKSLFCLNLMSSPGSGKTTLLEETIRRLKAKRPIYVIEGDQQTSND
                     ADRIAALEIPVFQVNTGTGCHLEADMVNHAVKHLNPKEGAILFIENVGNLVCPAMFDLG
                     ESKKVVIVSTTEGDDKPLKYPHIFQEADICVINKIDLAPYLNTKVEVLRENALKVNHHL
                     QIFEVSATKGDGMDAWCDWLQTESAKCK"
     CDS             3166..5226
                     /gene_functions="biosynthetic (rule-based-clusters)
                     OD_unknown: CoA_binding_2"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     OD_unknown: Succ_CoA_lig"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg42_4"
                     /sec_met_domain="Succ_CoA_lig (E-value: 6.6e-37, bitscore:
                     116.4, seeds: 149, tool: rule-based-clusters)"
                     /sec_met_domain="CoA_binding_2 (E-value: 5.8e-22, bitscore:
                     68.5, seeds: 225, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MINRELINPQSIVVVGGSNNVHKPGGRIVRNLLDGKYKGELCVVN
                     AKETDVQGVKSYPSVHDIPETELAIISIPSKSCPEVMEVLARQKGVKAFIVISAGFGEE
                     THEGGILEQQMLDVVNEAGASLIGPNCIGLMNMNYHGVFTQPIPEFHPDGVDFISSSGG
                     TALFIIESALTKGLRFSSVWSVGNSKQNGVEDILEYMDRNFDPVLDSKIKMLYIEQIKQ
                     PDKLLYHASSLIRKGCKIAAIKAGSTESGKRAASSHTGAIASSDSAVEALFRKAGIVRC
                     FSREELTTVASIFTLKDVKGKNCAIVTHAGGPAVMLADALSKGRLNVPSLEGPIADELK
                     SKLYPGAAVGNPIDIIGTGTPEHLATAIDFCENRFDNVDLMMVIFGSPGLVKLYDTYEV
                     LHKKMEECKKPIFPILPSIVTAGPEVKSFVKKGHVNFSDEVTLGTALSRVINTPKPMST
                     DIQLYGVDVPEVRRIIDRLPGSGYLNPEEVRTLLRAANIPLVEEYASDDRDALLAFAKK
                     VKYPVVAKVVGPVHKSDIGGVALNIRGEEHLLFEYERMMRLPGVTGIMVQPMLKGQELF
                     LGAKYEDRFGHVVLCGLGGIFVEVLKDVSYGLAPLSYDETYSMIRSLRGYPIIKGTRGQ
                     KGIDEQQYADIIVRLSTLLRFASEIKEMDINPLVATDRGLFAVDARIRIEK"
     CDS             complement(5315..5929)
                     /locus_tag="ctg42_5"
                     /transl_table=11
                     /translation="MTIAFIRTYNNKQNSEVQEAVIREFAESQKIEIGKWAKEVGNSPR
                     ANRRLESIVKSLSPGDEILVSDISRVSRKMIEIIHIILLCIERKVTLRSVSDGYVFEDN
                     IDSKTLAFTFGLVSEIERKLVSIRTKEALALIRSKGVVLGRPKGSQQMGRLEPYKEQIE
                     KDLKDPSLTYAQIAEKYNVSLSSFKRFLKEYLPDKKKKKKK"
     CDS             5999..6181
                     /locus_tag="ctg42_6"
                     /transl_table=11
                     /translation="MKHFNSVGLKTKKPTNKFISWLFAEAGGFEPPVPLRVRQFSKLVV
                     SATHPHFLVCSVLLP"
     CDS             6295..7344
                     /locus_tag="ctg42_7"
                     /transl_table=11
                     /translation="MDLNKQILSRRPIIIALIAILVVLIGGGGFWVYRLAWAPNFKPDK
                     TVYVYIDDKKDFDDLCRQLRDSANCLRIGSFKQLSGLLKYPASMRTGRYAVKPGMSNLT
                     LLNDLRRGHQVAARVTFNNIRFKEDLAERISDQLMFGKENLLRLLNDSVYCDSLGFTPE
                     TINALFIPNTYEIYWNISADKFIRRMKREYDAFWTPERLKQAEEIGLTPVEVSILASIV
                     EEETAASDEYPIVAGLYINRLHAGIPLQADPTVKFAVGDFSLRRILFEHLEIDSPYNTY
                     KYAGLPPGPLRIPTIKGLNSVLNHTKHKYLYMCAKEDFSGRHNFAVTLAEHNRNANRYR
                     AELNRRRIR"
     CDS             7449..9050
                     /gene_functions="biosynthetic (rule-based-clusters)
                     OD_unknown: POR_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg42_8"
                     /sec_met_domain="POR_N (E-value: 1.7e-14, bitscore: 44.1,
                     seeds: 31, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 2e-18, bitscore:
                     56.6, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEKHLFLGDEAIAQAAIDAGISGVYAYPGTPSTEITEYIQGSPVT
                     KERGIHCRWSANEKTAMEAALGMCYAGKRALCCMKHVGLNVAADCFMNAAMSGINGGMI
                     ILTADDPSMHSSQNEQDNRIYGNFAMIPMFEPSSQQEAYDMVYHGFELSEKLGYPILLR
                     VTTRMAHSRAGVVTSPLKPENRMNCPEDGRQRFILLPALARKRFKSLLASQEAFTEASE
                     NSAYNKYFDAPNKDLGIITTGIAFNYLSENYPDGFEHPVLKISQYPLPRKQVEKIVGEC
                     KEILVLEEGYPVVEEQLKGFLGKGVTVHGRLDGTLQRDGELTPDAVGKALGKEIQSYYA
                     IPEVVEQRPPALCQGCGHRDMYEALNEVIAEYNGTAKVFGDIGCYTLGALPPFRAIDSC
                     IDMGASITMAKGASDAGVFPAISVIGDSTFTHSGMTGLLDCVNENTNITIVISDNETTA
                     MTGGQDSAGTGRLESICAGIGVDPAHIRVMVPLKKNFEEMKSIIREEIEYKGVSVLIPR
                     RECIQTLTRKKKASKK"
     CDS             9047..9628
                     /gene_functions="biosynthetic (rule-based-clusters)
                     OD_unknown: POR"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg42_9"
                     /sec_met_domain="POR (E-value: 2.6e-43, bitscore: 138.1,
                     seeds: 86, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKTDIILSGVGGQGILSIAAVIGEAALKEGLYMKQAEVHGMSQRG
                     GDVQSNLRLSDEPIASDLIPKGHADLIISLEPMESLRYLPYLKKEGWLVTNSRPFVNIP
                     NYPEIEKVNAELDKLPHKVVLDVEEIAKEAGSVRAANIVMLGAATPFIGIEYDKIEAGI
                     RQIFGRKGEDIVNMNLKALKAGYDLAQSLR"
     CDS             9776..10351
                     /locus_tag="ctg42_10"
                     /transl_table=11
                     /translation="MRFDENFNVSLWLNPKREMIKVMKKYLLASLLALLAFVGKAQEDN
                     SDIVKVGDAMPSFTIVSDNGSKLQSASLKGKVILVNFFATWCPPCQKELAAVQQTLWPK
                     YKNNKDFVLLVIGREHSDADLQKYNEKKGFDFPLYPDKDRAIFGAFAKNLIPRGYLVGK
                     DGKIIYTSKGYTDEEFAELMTKIEGALK"
     CDS             10357..11145
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_7"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg42_11"
                     /sec_met_domain="Fer4_7 (E-value: 6.1e-11, bitscore: 32.9,
                     seeds: 208, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4 (E-value: 6.4e-11, bitscore: 31.8,
                     seeds: 528, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 1.3e-05, bitscore: 15.7,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKYSNIHLIYFSPTHTSAKIVYAIAEGMGATSMSESDVTCESLDM
                     EEYIDDELTIIAAPVYGGRVAETAMERFRMFRSAHHAPVVPVVLYGNRDYEDALKELCD
                     LVSEQGFVPVAAGAFIGEHSFSRKGMPIAEGRPDESDLNQATEFGKKIIEELEKVSCVE
                     CLSALEVKGNFPYRVKGPSTPQAPVTDNDLCTQCEYCVDVCPTHAISLADEGMYSDPNL
                     CIKCCACVKECPEGARTFDTPYTAMLHKNFSARREPEIFF"
     CDS             11267..13693
                     /locus_tag="ctg42_12"
                     /transl_table=11
                     /translation="MKTYLFLLLFVFQAFSLSSQISLKGYNQEKIDPSLFEGRWKARWI
                     SYPGEAPNVYGVYHFRKSFDLEVVPSRFIVHVSADNRYKLYVNGKLVSLGPARGDIYNW
                     SFETVDLAPYLRKGKNTLASVVWNYAERKPVAQISYDQTGFILQGNTGHEAVVNTDTTW
                     VCLRNKAYAPWTEWQVLGYYVAGPGEELEASAYPWGWEQPDYDDRKWEKAVRGMEGATK
                     GSRDYPGRLLVPSPIPPMDSRIERLAKLRRSEGIECPQGFPYWPKALTIPANTEVRLLL
                     DNDYLTTGYFSLAFSKGKEAEIHIGYSEALYKQEEESTTKSYALNGKGHRDELTDKQFI
                     GYGDKILADGGDNRLFTSLWWRTWRYVELKVKTASEPLVIEDMYGTFSAYPFRNETTFS
                     APGHEELGRMLKIGWRTARLCANETYMDCPYYEQLQYFGDTRIQAMISMYNTSDPYMVK
                     NAIEQGRQSMVAEGITMSRYPSSVHQFISSFSLWWICMGHDYWMYRGDEAYMKTLLPAY
                     RQVLSWYEQWLKPDYSLSYVPHWFFVDWAAGFDYGEPIREKEGNSALQDLMYIMTLEFA
                     AEMEQAIGLPAMADHYRKIATEMRKTIRPKYWDAARNLFADTQDHRSYSQHVNALAILT
                     GVTKGEEAVKVMNQTLADTSLIQCTIYFRYYLNQALKVSGLGDQFLDNLQIWRDQMALG
                     LTTWAEMPEPSRSDCHAWGASPNIEFYRILLGIDSDAPGFRKIRIAPSLGKLKEVSGTI
                     PHPLGSVTAAYKLNERGEGTARLVLPEGTTGIFIWNGKEIPLKPGEQVISLSSRH"
     CDS             13712..15442
                     /locus_tag="ctg42_13"
                     /transl_table=11
                     /translation="MRRVYSIALLLLVALGLSATTKEVKLKLVETSDIHGNFFPYNFIE
                     QREWGGSLARVYSFVQEERRAYGDNLLLLDNGDILQGQPSAYYYNFMDTVSTHIASAMM
                     NYMGYNVGNMGNHDVEAGHAVFDRWIKQCDFPILGANIIRTSDRETYLKPYEVFERDGV
                     KIVVLGMITPAIPVWLPETLWQGLYFADMEETARKWMKIIQEKEKPDVVVGIFHAGNEA
                     RTMSGQYREDASMEVAQRIPGFDVVMMGHDHRRYCGKVANIEGDSVLLINPASNGRVVG
                     SVDVVLKMEHGKVLDKQVSGVLTDVDKLEPSKEFMEKFAPQYKAVNDFVSEKVGTFTES
                     IATRPAYFGPSAFIDFIHSLQLELTGADVSFAAPLSFDAKIDKGDITISDMFSLYKYEN
                     MLYTMNLTGAEIKGFLEESYAMWTNRMKSPDDHVLLLKERKKGQENYVSFVNFSFNFDS
                     AAGIIYTVDVTKPEGEKITILKMADNRPFDENKTYKVALNSYRGNGGGELLTKGAGIPQ
                     DELKSRIIHSTDKDLRYYMIQYIKEKGVLSPQPLNQWQMIPQDWTRPAAERDCKFLFGE
                     "
     CDS             complement(15683..15907)
                     /locus_tag="ctg42_14"
                     /transl_table=11
                     /translation="MKSCEMHLVLVLSDHVNVGKDLLYRPPKTQKAEEGRTTQTTVYPH
                     VKASGKFPGKNPRAQKAHLYAFKETFLEK"
     CDS             16138..16293
                     /locus_tag="ctg42_15"
                     /transl_table=11
                     /translation="MFYNTSFAPAFERERRSKMMKQTFRKKSSEIIWKFKIKVLIFAAT
                     FAKRKRQ"
ORIGIN
        1 tcgacaaact gttatttttc tatctattta tttgggtggg aaactttagt tattaattgt
       61 acgcattgtg gccctcgttt ctctattatc cgggaccttc cttacgaccg ttcgcagaca
      121 acgatgggcg gtttccttat gtgtcccgat tgtgagaaag aatatacgaa tgttatcgat
      181 cgccgtttcc atgcccaacc ggtcgcttgc aatcattgtg gcccgactta ttacgcgact
      241 tataacgagg agacttatat cgattatgag accttattga aacttacctc tcgtctattg
      301 cttggtggag aggttattgc ggctaaagga atcggaggct atcatttgat ttgtgatgcc
      361 tcgaacgaga gagcggttgc ccgtctgcga gagataaagc agcgggatac caaaccattc
      421 gctgttatgt tccgtgattt ggaacatttg caggtctata cggctacgga accgatggag
      481 gagcgatgcc tcgtctcttg gcgccgtccg atcgtgctgc tgaggcaacg gagccggtta
      541 gcttccggaa tcaatccggg catgcatacg ctaggatgta tgttgtctta tatgccgatt
      601 cattacgatt ggtttgctcg tacagggata cctgcgttgg taatgaccag cgggaatcta
      661 agcgatttgc caatagcgat caccccggag gatgcggagg cgcaattagc gggaaaggta
      721 gcggtcctct tgcatcataa tcgcccgatc cataaccggg tagatgattc tgtattgcag
      781 gtctgcggag gacaaccttg cttgatccgt cgttcccggg gctatgtgcc ggaacccttt
      841 ttcacggata caaatgtgga ggggatcatg gctttcggtg cggagaaagt gaacacgttc
      901 gctttgggga aaggagagac gatcctgcaa agtcaatata ttggcgactt aaagaactgg
      961 gagactttcc ggttctatac ggaatctatg gagcggtttc gtcatttgtt tcgtttcaat
     1021 ccccagcgat tggtttgtga cctgcatccg gattatcttt ccagccaaga ggcggaacgt
     1081 atctcgaaat ctctttcctt acctttatta aaggtacaac atcatcatgc tcatgccgct
     1141 gcttgtatgt tggagcatgg attgaatgag ccggttctcg ctatcgtgat ggatgggaca
     1201 ggtctgggtg atgatggtaa ggtttgggga ggcgagttct tcttttgtga ccgagcgaaa
     1261 taccgtcgcc tttcccattt tgagtatgtc ccgttaccgg gaggcgacaa ggcggctgag
     1321 gagccatggc gaatggttgt cgcctatttg tggcattatt tcaaggacga accgtcgggt
     1381 attccttatc cggccgattt cgtggaacgc ataggcacgg aaaggatcgc tatgcttgaa
     1441 cgaatgatgg agaaaggtgt gaatacaccc tatacatcca gcgctggccg gctgtttgat
     1501 gcggtagctt ctttattggg gatttgcgat gtctccagcc accaagcgga ggctccggtc
     1561 ttattggagc aggcggcgat gggagagagg aacgcttatg cgtatccagt ctcggcggag
     1621 ggagaggaaa tctcttttta ttctttgttt gaggcattat tgcatgataa gacgaacgag
     1681 gtcccggtga gcttgatatc cgcccgtttc catacgacat tggcttcctt gtttgtgcag
     1741 aaagcccgct tgttgattaa acggacgaaa gcgacacaag tggttatctc gggaggatgt
     1801 ttccagaata aattattgac ggagtcgatg aggagacagt tcatcatggc tggggtcccc
     1861 gtctatattc cgtctcgtat accttgtaac gatgggggga tagccgtggg gcaattaacg
     1921 atcgcctcgg tgactccctt ttaaaagaga tcagatatgc atgagttgtc tatagcccgt
     1981 agcatcgtgg agctggtcga ggaacaagcg gataaccggg gagcctcggt ggtcgaagag
     2041 ttggagttag agataggaca tttgtccggc gtagagatcc aaaccttagc gttcgcattg
     2101 gatagcgcca taaaaggtag caagctggaa aaggcccgga ttatccgtca ttatattgag
     2161 ggggaaggac agtgtagcga ctgtgagacc attttcccaa tgaacgcctt gttttcccct
     2221 tgtccccatt gtggctccta tttagttaaa atccttaaag ggaaggaact tcgggtgaag
     2281 tcgattgtta ttaaaaagga atgatatatt aatgaaataa aaacttaaat actatgtgcg
     2341 gaacttgcgg atgcggagag catcatcacc atcacgatca tacgcatgag cattctcatg
     2401 gccatgaaca tcatcaccat cctgatgaag ggatcgtaat caatctggaa caagatatac
     2461 ttcaacgtaa caacttattg gcggagcgaa accggggata tttcgaggct aagagcctgt
     2521 tctgcctgaa cttgatgagt tcgcccggat ccggtaagac aactttgctg gaagagacga
     2581 tccgccgttt gaaagcgaag cgaccgatct atgtgataga aggcgatcaa caaacctcaa
     2641 acgatgccga ccgtatagcg gcgttggaga ttcccgtgtt tcaggtaaat accggtaccg
     2701 gctgtcattt ggaagccgac atggtcaatc atgccgttaa gcatctgaat ccgaaggagg
     2761 gagcgatcct ttttatagag aatgtcggca atctggtctg tccggccatg ttcgatctcg
     2821 gagagtccaa gaaagtcgtt atcgtgagta cgacggaggg agatgataaa ccgttgaaat
     2881 acccacatat ctttcaggag gcagatatct gcgtaatcaa caagattgat ctggctcctt
     2941 atctgaatac aaaagtggaa gtgcttcggg aaaacgcctt gaaggtaaat caccatctcc
     3001 agatattcga ggtgtccgcc acgaaaggag acgggatgga tgcatggtgt gactggttgc
     3061 agacagagag tgcaaagtgt aaataaatac cccgggtttt aatgaataaa tggagaaaaa
     3121 aactatattt gctcccattc attgaatcta actaatcaaa atgttatgat taaccgagaa
     3181 ttgattaatc ctcaaagcat cgtagtggtg ggaggttcca acaacgtaca taaaccgggc
     3241 ggtcgtatcg tgcgaaacct gttggatgga aaatataaag gagaattatg tgtggtaaac
     3301 gccaaggaga cagatgtgca aggcgtcaag tcttatcctt ctgtacatga tatcccggag
     3361 actgagttgg cgatcatctc gattccgagt aaatcgtgcc ccgaggtgat ggaagtgctg
     3421 gcccggcaaa agggggtaaa agcttttatc gtgatctcgg ccggcttcgg cgaggagaca
     3481 cacgagggcg gtatcttgga gcaacagatg ctggatgtcg tgaatgaggc gggagcttcc
     3541 ttgatcggcc cgaactgtat cgggttgatg aatatgaatt atcatggcgt gtttacgcaa
     3601 ccgataccgg aattccatcc cgatggcgtg gatttcatct ctagctccgg cggtacggcc
     3661 ttgttcatta tcgagtcggc gctgacaaaa gggctgcgtt tctcttctgt ttggtcggtt
     3721 gggaactcca agcagaatgg agtagaggat atccttgaat atatggatcg gaactttgat
     3781 ccggtattgg attccaagat caagatgttg tatatcgagc aaatcaagca accggataaa
     3841 ttgttgtatc atgcgtcttc cttgatacgt aagggatgca agatcgccgc tatcaaggcg
     3901 ggaagtacgg agtcgggaaa gcgagctgcc tcttcgcata cgggcgctat cgctagttcg
     3961 gactctgccg tggaggcttt gttccgtaag gcgggtatcg tgcgttgttt tagccgtgag
     4021 gaattgacta ccgtggcgag tatctttacc ttgaaagacg tgaaagggaa gaattgtgcg
     4081 atcgtgacac atgccggagg gcctgcggta atgctggcgg acgctttatc caaggggcgt
     4141 ttgaatgttc ctagtttgga aggccctatc gctgatgagt tgaaatccaa actgtatccg
     4201 ggtgccgctg tcggtaatcc gattgatatt atcggtacgg ggacaccgga acatctggct
     4261 acagccatcg atttctgtga gaatcgtttc gataatgtgg atttgatgat ggtcatcttc
     4321 ggtagtcccg gtttggtaaa actttatgat acctatgagg tacttcataa aaagatggaa
     4381 gagtgcaaga agccgatctt cccgatatta ccgtctatcg taacggccgg accggaggtg
     4441 aagagctttg tcaagaaagg ccatgtgaac ttctcggacg aggtgacatt gggtactgcc
     4501 ctttcacggg tgatcaatac gccgaaaccg atgagcacgg atatccagct atatggcgtg
     4561 gatgtaccgg aagttcgtcg tatcatagac cggttgccgg gtagcggtta tttaaatccg
     4621 gaggaagtgc gtacattgtt gcgtgccgct aatatcccgt tagtggagga atatgcttcg
     4681 gatgataggg atgcgttgct ggcttttgcc aagaaggtga aatatccggt ggtagccaag
     4741 gttgtggggc ctgtgcataa gagcgatatc ggtggtgtgg ccttgaatat ccgtggagaa
     4801 gagcatttat tgttcgagta tgaacgtatg atgcgtctgc cgggtgttac gggcatcatg
     4861 gtacaaccga tgttgaaagg acaggaatta ttcttgggag ctaaatatga ggatcgtttc
     4921 ggccatgtgg tactttgcgg gttgggtgga atcttcgtgg aggtattgaa ggatgtgtct
     4981 tatggtttgg caccgttatc atatgatgag acttattcaa tgattcgttc tttgagaggg
     5041 tatccgatca ttaaaggtac gcgtgggcaa aagggcatcg acgagcaaca atatgcggac
     5101 attatcgttc gcctctctac cttattgcgt tttgccagcg agataaaaga aatggatata
     5161 aatccgttgg tggctacgga tagaggcttg ttcgctgtag acgcccgtat ccgtatagag
     5221 aaataataat gattcaatgt gccaatatgc gaatatgcta atatctgaat tatccacttc
     5281 tggtatttca ttggcatatt ggcacattga atcattattt cttcttcttc tttttcttat
     5341 cgggaagata ctctttcaga aagcgtttga agctacttag cgatacattg tatttctccg
     5401 ctatctgggc gtaagtcaag ctcgggtctt tcaagtcttt ctcgatttgt tccttataag
     5461 gctccaagcg tcccatttgt tgactacctt tcggacggcc cagcaccaca cctttacttc
     5521 tgatcaaggc aagggcttcc ttcgtacgga tagagaccag ctttcgctcg atctcggaga
     5581 ccagaccgaa ggtaaaggcc aaagtcttac tgtcgatatt atcctcgaac acatatccgt
     5641 cgcttacgct acgaagcgtt acctttcgct ctatacaaag caaaatgata tggatgatct
     5701 cgatcatctt acggctcaca cgggatatat cggacacaag tatctcatcc ccgggactta
     5761 aagatttgac aatactttcc agtctgcggt tcgcacgagg actatttccc acctctttag
     5821 cccacttccc gatctctatc ttctgagatt cggcaaattc ccggatcaca gcttcttgga
     5881 cctcggagtt ttgcttatta ttatatgttc ggataaaagc aattgtcata atgtatatat
     5941 ttaattatct ccttttaata acagatcgac ttacgataag ttcaaatatg acaaatatat
     6001 gaaacacttt aattcggttg gcttaaaaac aaaaaaacca actaataaat ttattagttg
     6061 gctctttgcg gaagcggggg gattcgaacc cccggtaccc ttacgagtac gtcagtttag
     6121 caaactggtg gtttcagcca ctcacccaca cttccttgtg tgttctgtgc ttcttcctta
     6181 gaattgcgat gcaaaggtag aactataatt ttaaataaac aaggctttgc acatcatttt
     6241 tttcgaaaaa agatactact tttgtgcctt attctgatat tcaatagatt attcatggat
     6301 ttgaacaaac aaattttatc gaggcgtccg ataattatcg ccttgatagc gattctcgtt
     6361 gttttgatag gcggtggagg cttttgggtg taccgtttgg cttgggctcc gaattttaag
     6421 ccggataaga cggtctatgt ctatatagat gataaaaagg attttgatga tctttgccgg
     6481 cagttgaggg attcggcgaa ctgtctccgt atcggtagct ttaagcaatt gagtggattg
     6541 ttgaagtatc ctgcgtccat gcgtaccggt cgatacgccg tgaagcccgg catgagtaat
     6601 ttaaccttat tgaatgattt gcggagagga catcaagtag cggcccgggt tacttttaat
     6661 aatatccgtt tcaaggaaga tttggcggaa cgtataagtg atcaattgat gttcgggaag
     6721 gaaaatctct tgcgtctatt gaatgattct gtgtattgcg actctttagg ttttaccccg
     6781 gaaacgatca atgccctctt cattcctaat acctatgaga tttattggaa tatatccgca
     6841 gataaattta tacgtcgcat gaagcgtgaa tatgacgctt tctggacacc ggaacgattg
     6901 aaacaggcag aggagatcgg gcttactcca gtcgaggtat ctatcttggc ttctatcgta
     6961 gaagaggaga cggcggcatc ggacgaatat ccaatcgtgg cgggccttta tatcaaccgc
     7021 cttcatgctg gtattccttt acaggcagac cctaccgtaa agttcgcggt gggggatttt
     7081 tctttgcgac gtatcttatt tgagcatttg gaaatagatt ctccctataa tacctataaa
     7141 tatgcgggcc tgcctcccgg tcctctacgg attcctacta tcaagggctt gaatagcgta
     7201 ttgaatcata cgaaacataa atacttatac atgtgcgcta aggaggattt ctcgggacgg
     7261 cataatttcg ccgtgacgtt ggcggagcat aaccgcaatg ccaaccggta tcgggcggag
     7321 ttgaataggc gccggatacg gtaatggatc tagtataaat cataagtctc tcattctaaa
     7381 ttgaacattt ttcattacct ttggcggcta aatagtgtga atagtcaata ttaagaaaac
     7441 agatacacat ggaaaaacat ttatttttgg gggacgaggc catagcgcaa gccgctatag
     7501 acgctggaat ctccggggta tacgcatacc cgggaacccc ttctactgaa atcacagaat
     7561 atatccaagg ttctccggta acgaaggaaa gaggtatcca ttgtcgctgg agcgcgaatg
     7621 agaaaaccgc catggaagcc gctttgggta tgtgctatgc cggtaaacgt gcgctttgct
     7681 gcatgaagca cgtgggtttg aatgtagccg ccgattgctt tatgaacgcc gctatgagcg
     7741 gtatcaacgg aggtatgatc atccttacgg ccgacgaccc atccatgcac tcttcccaga
     7801 atgagcaaga caaccgtatt tatggcaatt tcgccatgat cccgatgttt gagccatcca
     7861 gccagcaaga ggcttatgat atggtatatc atggattcga gttatccgag aaattagggt
     7921 atcctatctt gctgcgtgta acgacccgta tggcgcattc tcgtgccggt gtcgtaacca
     7981 gcccgttgaa gccggagaac cggatgaatt gtccggaaga cggtcgtcaa cgttttatct
     8041 tactcccggc attggctcgt aaacgtttca agagtttgct ggcgtctcaa gaggctttca
     8101 cggaagcttc cgagaattcc gcgtataata agtatttcga tgccccgaat aaagacttgg
     8161 gtatcatcac gacgggtatc gctttcaatt atctttccga gaattatccg gacggtttcg
     8221 agcatcccgt attgaagatc tcccagtatc cgcttccgag aaagcaagtg gagaagatcg
     8281 ttggcgagtg taaggagatc ttggtgttgg aagagggata tccggtcgtt gaagagcaat
     8341 taaaaggttt cttggggaag ggcgtgacgg ttcatggccg tctggacggt acgcttcagc
     8401 gtgacggcga gcttacgcca gacgcggtag gcaaagcctt gggtaaggag atccagagct
     8461 attacgcgat ccccgaggtg gttgagcaac gtccgcccgc attgtgccaa ggttgtggac
     8521 accgggatat gtatgaggcc ttgaacgagg tgatcgccga gtataacggt acggctaagg
     8581 tgtttggcga tatcggctgt tataccttgg gagctttgcc tcctttccgt gcgatcgatt
     8641 cttgtatcga tatgggcgcc tccatcacga tggcgaaggg cgcttccgat gcgggtgtat
     8701 tccctgctat ctccgtgatc ggcgattcta cgtttaccca ttccggtatg actggtttgc
     8761 tggattgcgt gaacgagaac acgaatatca ccatcgttat ctccgataat gagacgacgg
     8821 ccatgaccgg agggcaggat tccgccggaa caggacgtct ggagtctatc tgcgccggta
     8881 tcggtgtgga tccggctcac atccgtgtga tggttccttt aaaaaagaac ttcgaggaga
     8941 tgaagtctat catccgtgag gaaatcgagt acaagggcgt atccgtattg atcccccgcc
     9001 gtgagtgtat ccagacatta accagaaaga aaaaagcaag caagaaatga aaacagatat
     9061 tatactatca ggtgtaggag gacagggtat cctttctatc gccgccgtta ttggagaagc
     9121 cgccttaaaa gaaggtctgt atatgaagca agcggaagta cacggtatga gtcaacgggg
     9181 tggagacgtg cagtctaacc tgcgtctttc cgacgagccg atcgcctcgg acttgatccc
     9241 gaagggccac gccgatttga tcatctcctt ggaaccgatg gagagcttgc gttatctgcc
     9301 ttacctgaag aaagagggtt ggctggtgac gaactcccgt ccgttcgtga acatcccgaa
     9361 ctatccggag atcgagaaag tgaacgccga gttggacaag ctccctcaca aggtcgtatt
     9421 ggacgtggag gagatcgcca aggaagcggg ttctgtccgt gccgccaata tcgtgatgct
     9481 gggggctgct accccattta tcgggatcga gtatgataag atcgaggcgg gaatccgtca
     9541 gatattcggt cgtaagggcg aggatatagt taatatgaac ctaaaggcat tgaaagccgg
     9601 ttatgactta gcgcaaagtc tgcggtaaat ctttctccgg gtttgcatgg tatcagcgta
     9661 cgtgacatct ccgggtttca cgtacgtttt ttttaacatc taacccccta gaacttttag
     9721 aagagctgtc gaggggtagg tacagcatcg tagaactttc gtaagcctta gaattatgcg
     9781 gtttgatgag aattttaatg tatctttgtg gctgaatcct aaacgagaaa tgattaaggt
     9841 tatgaagaag tatttattgg ctagtttact agcgttattg gctttcgtag gcaaagctca
     9901 ggaggataat tccgatatcg tgaaggtcgg tgatgccatg ccgtcattta cgattgtttc
     9961 cgacaacggg agtaagttgc agtccgcttc gttgaaggga aaagtgatcc tcgtgaattt
    10021 tttcgccact tggtgtcctc cttgccaaaa agaattggcc gctgtccaac aaaccctctg
    10081 gccgaaatac aagaacaaca aggacttcgt tctcttggtg atcgggcgtg agcattccga
    10141 tgccgatcta cagaaatata acgagaaaaa aggcttcgat tttcctttgt atcccgataa
    10201 ggaccgggct attttcggcg ctttcgccaa gaacttgatc cctcgtggct atttggtcgg
    10261 aaaagacggg aagatcattt atacgagcaa aggctatacc gatgaggaat ttgctgagtt
    10321 aatgactaaa atagagggcg cgttaaaata agaatcatga aatatagtaa catacattta
    10381 atttattttt ctccgacaca cacgtccgcc aagatcgttt acgcgatagc ggaaggaatg
    10441 ggtgccactt cgatgtccga gtcggatgtc acttgtgaga gtctggatat ggaagagtat
    10501 attgatgatg agctgacgat tatagccgct cctgtatacg gtggccgtgt ggcggagact
    10561 gccatggaac gttttcgcat gttccgttct gcccaccatg cgccggtagt ccccgtggta
    10621 ctgtatggga accgggatta tgaggatgcc ttgaaagagc tctgtgattt agtgtcggag
    10681 caggggttcg tacctgtggc tgccggagcg tttatcggcg agcattcttt cagccgcaag
    10741 gggatgccca ttgccgaggg gcgtccggac gagtcggatc ttaatcaggc tacggaattc
    10801 gggaaaaaga ttatcgagga gctggagaag gtttcctgcg tggaatgctt gtccgccttg
    10861 gaggtgaaag gtaatttccc gtatcgggtg aaaggccctt ccactcctca agctcctgtt
    10921 acggataacg atttatgtac gcaatgtgag tattgcgtgg atgtgtgtcc tacacatgcg
    10981 atatccttgg cagacgaggg tatgtatagc gacccgaacc tatgtatcaa atgttgcgcc
    11041 tgcgtgaaag agtgtcccga gggcgcacgt actttcgata ctccttacac ggcgatgctc
    11101 cataagaact ttagcgcgcg cagggagccg gagatattct tctaatggag gaccgggcat
    11161 ccggtatatg gtgagggaaa gcgtcaaaag gcaaaagttc ttttggcgct ttctcttttt
    11221 ttgtaccttt gttcggatcg ttaatctcaa ataataccgt gtttgtatga aaacctattt
    11281 attccttttg ctttttgtgt ttcaagcctt ctccctttcc tcccagatta gcctgaaagg
    11341 gtataatcag gagaagatcg atccttctct tttcgaggga cgatggaaag cccgttggat
    11401 ctcctacccg ggtgaggccc cgaatgtata tggggtctat cattttcgta aatcgttcga
    11461 tctggaggtg gttccttccc ggtttatcgt ccatgtttcc gccgataacc gttataaatt
    11521 atatgtaaac gggaaattgg tatccttggg cccggcccgt ggggatatct ataactggag
    11581 tttcgagacg gtggatctgg ctccttatct gaggaaaggg aagaatacgc tggcctccgt
    11641 tgtctggaat tatgccgagc ggaaacctgt cgcccagatc agttacgatc agacgggttt
    11701 tatcctgcaa ggcaatacgg ggcatgaggc ggtggtaaat acggatacca cttgggtctg
    11761 cctgcgtaat aaggcgtatg ctccttggac cgaatggcag gtattggggt attacgtggc
    11821 tggcccgggt gaggaactgg aagcctccgc ttatccttgg ggctgggaac aaccggatta
    11881 cgacgacagg aaatgggaga aggccgtacg gggcatggag ggtgccacga aaggatcgag
    11941 agattacccg ggacggttgc tggttcctag cccgatacct ccgatggaca gccggatcga
    12001 gcggctggcc aagctccgcc ggtcggaagg gatcgaatgc ccgcaaggat ttccttactg
    12061 gccaaaagct ttgacgatcc cggcgaatac agaggtccgc ttgcttctgg ataatgatta
    12121 cctgacgacg ggttatttct ccttagcctt cagcaaagga aaggaggccg agatccatat
    12181 cggttattcg gaagccctct ataagcaaga agaggaatcg accactaaat cgtatgcgtt
    12241 gaatggcaag ggacatcggg acgagttgac ggataagcag tttatcgggt acggggataa
    12301 gatactggct gatgggggag ataatcgtct cttcacgtcc ctgtggtggc gtacatggag
    12361 atatgtggag ttgaaagtga agacggcttc cgagcctttg gtgatcgagg atatgtatgg
    12421 gactttctct gcctatcctt tccgtaacga gaccactttc tccgctccgg gacatgagga
    12481 gctgggccgt atgctcaaga taggatggcg taccgcccgt ctgtgcgcca atgagacgta
    12541 tatggactgc ccgtattacg agcaactgca atatttcggg gatacacgca tacaggcaat
    12601 gatttccatg tataatacat cagaccctta tatggtgaag aatgccatag agcaaggacg
    12661 gcagtccatg gtggcggaag ggattacgat gagccgatat ccgtctagcg tacatcagtt
    12721 tatatcctcg ttctctctct ggtggatttg tatggggcac gattattgga tgtaccgtgg
    12781 ggatgaggca tacatgaaga ccttgcttcc cgcttaccgt caggttttgt cgtggtacga
    12841 gcaatggttg aagccggatt atagtttgtc gtacgttcct cattggttct tcgtggattg
    12901 ggcggccggt tttgattatg gcgagccgat acgggagaaa gagggaaact cggcgctcca
    12961 agatttgatg tatataatga ccttggagtt tgcggcggag atggaacaag cgatcggcct
    13021 ccctgccatg gcggatcatt accggaagat cgctaccgag atgcgtaaga cgatccgccc
    13081 gaaatattgg gacgctgccc gtaatctatt cgccgatacg caggatcatc gcagctattc
    13141 ccagcatgtg aacgccttgg cgatcttgac tggggttacg aaaggggagg aggccgtaaa
    13201 ggtgatgaac caaaccttgg cggatacgag cttgatccag tgtacgatct atttccgtta
    13261 ttacttgaat caagcgttga aagtttccgg tttaggggat cagttcttgg ataacttaca
    13321 aatatggcgg gatcagatgg cgttgggatt gaccacatgg gcagagatgc cggagccatc
    13381 ccgttctgat tgccatgctt ggggagccag tccgaatatc gagttttacc ggatcttgtt
    13441 ggggatagat agcgatgctc ccggatttag gaagatacgg atcgctccgt ctttgggaaa
    13501 actgaaggag gtttccggta cgatcccaca tccgcttgga agcgtgaccg ccgcttataa
    13561 attgaatgaa agaggtgagg gaaccgcccg tctggtcttg ccggaaggta ctacgggtat
    13621 atttatctgg aatggaaaag aaatcccgtt gaaaccgggc gaacaggtta tttcgttatc
    13681 ttcgcgtcat taatctatct aaaatcctga tatgagacga gtttattcaa ttgccttatt
    13741 gctgctggtc gctctcggtc tgtcggcgac aacgaaggaa gtaaagttga aattagtgga
    13801 aaccagtgat atccatggaa acttcttccc gtataatttt atcgagcagc gggagtgggg
    13861 aggaagtctg gcacgggtat attcgttcgt gcaagaagaa cgccgggcgt atggcgataa
    13921 ccttttgcta ttggataatg gcgatatctt gcaaggacaa ccttcggcgt attattataa
    13981 tttcatggat acggtctcta cgcatatagc ttctgccatg atgaattata tggggtacaa
    14041 tgtgggaaat atgggtaacc atgatgtaga ggctggccat gccgttttcg atcgttggat
    14101 caaacaatgt gatttcccta tcttgggtgc caatattatc cgtacctccg accgggagac
    14161 ctatttaaag ccttatgagg tatttgagcg tgatggtgtg aagatcgttg tactggggat
    14221 gattactccg gccattcctg tatggttgcc ggagactctg tggcaaggtc tttatttcgc
    14281 cgatatggaa gagacggccc gtaaatggat gaagatcatt caggagaagg agaagccgga
    14341 tgttgtggta ggtatctttc atgcgggaaa cgaggctcgt accatgtctg gccagtaccg
    14401 tgaggatgcg tcgatggagg ttgcccagcg cattccgggc ttcgatgtgg ttatgatggg
    14461 gcatgatcat cgccggtatt gtggtaaggt ggcgaatatc gagggagatt ccgtgttact
    14521 gataaatccg gcaagtaatg ggcgtgtagt cggttccgtt gatgtcgtgt taaagatgga
    14581 gcatggaaag gttttggaca aacaagtatc gggtgttttg acggatgtgg ataagttgga
    14641 gcctagcaag gagtttatgg agaaattcgc tccgcaatac aaagcggtga atgattttgt
    14701 ctccgagaag gtgggaactt ttacggagag tatcgcgacc cgtcccgctt actttgggcc
    14761 atccgctttt attgatttta ttcactcttt acaattggag ttgactggtg cggacgtctc
    14821 ttttgccgcc ccgttatcct ttgacgcaaa aatagataaa ggggatatca cgatcagcga
    14881 tatgttcagt ctttacaaat atgagaatat gctttatacg atgaatttga cgggagccga
    14941 gatcaaaggt ttcttggagg aatcatacgc tatgtggacc aaccggatga aatctccgga
    15001 cgatcatgtc ttattattga aagagagaaa gaaaggacag gagaattatg tctcattcgt
    15061 caacttcagt tttaactttg actccgcagc tggtatcatt tacaccgtgg acgtaacgaa
    15121 accagagggt gagaagatta cgatcttgaa aatggcggat aacaggcctt tcgacgagaa
    15181 taaaacgtat aaagtagctc tcaactctta ccgaggtaat ggaggaggtg agttattgac
    15241 gaaaggggcc ggtattcccc aagacgagtt aaagagtcgt atcattcatt cgaccgataa
    15301 agacctccgt tattatatga ttcaatatat aaaggaaaag ggcgtactta gcccacaacc
    15361 tttaaaccaa tggcaaatga tcccgcagga ttggacgaga ccggcggccg aacgggattg
    15421 taagtttctt ttcggggaat gagtttccgt ccttgaagtg tctggtttgc gatagtatct
    15481 caatgggaaa cggtggtaaa gtcaatggaa tagagatggt ttctcaatga ctttacggcc
    15541 gtgtcccatt gacttttttg tatcccgtat cagggatgtt gctgataggt tagggcgcaa
    15601 agggcgcatc tttacgtatg tttctaaaac tttttctgta aataacgttt atacccctct
    15661 tgtctgtaga gtgatgtaaa tattattttt ctaaaaatgt ttctttgaaa gcgtaaagat
    15721 gcgccttttg cgccctagga tttttgccgg ggaattttcc tgatgcctta acatgtggat
    15781 atacagttgt ttgtgtggtt cttccctctt cggctttttg ggtctttggg gggcgatata
    15841 ataggtcctt acccacgttt acgtgatccg aaagcactaa aaccaagtgc atttcgcatg
    15901 atttcatgag ctaaaagccg ttttttctgt gtgatttcct atcggggcca agatcgtttt
    15961 tgtcgttttc atacgtgcaa atgtactcgt ggagcacttg ttttaagtgc acgtggtgac
    16021 acgtgaggcc acgtggtggg ccatgtgagc cgagaatgga tatcgacgta ttattaatgt
    16081 acgcgatccc cctcgtgaaa aaaacttgaa aaataatacc ggaaaagttt ggaggttatg
    16141 ttttataaca ctagttttgc acccgcattc gagagagaac gccggtccaa aatgatgaaa
    16201 caaactttta gaaaaaaaag ttccgaaata atttggaagt ttaaaataaa agtccttatc
    16261 tttgcagcca cgttcgcaaa acgaaagcga caa
//
