LOCUS       c00103_gnlPro..        14228 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|MCGKMBIC_103.
ACCESSION   c00103_gnlPro..
VERSION     c00103_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-05 16:04:50
            Original ID  :: gnl|Prokka|MCGKMBIC_103
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 14228
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..14228
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[6054:11204]"
                     /cutoff="2000"
                     /detection_rule="(Complex1_51K and minimum(5, [FMN_bind,
                     FeS, Fer4, Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N,
                     SLBB]))"
                     /neighbourhood="10000"
                     /product="Rnf_complex"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      6055..11204
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="(Complex1_51K and minimum(5, [FMN_bind,
                     FeS, Fer4, Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N,
                     SLBB]))"
                     /neighbourhood="10000"
                     /product="Rnf_complex"
                     /protocluster_number="1"
     cand_cluster    1..14228
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Complex1_51K and minimum(5, [FMN_bind,
                     FeS, Fer4, Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N,
                     SLBB]))"
                     /kind="single"
                     /product="Rnf_complex"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..14228
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Rnf_complex"
                     /region_number="1"
                     /rules="(Complex1_51K and minimum(5, [FMN_bind, FeS, Fer4,
                     Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N, SLBB]))"
                     /tool="gutsmash"
     CDS             complement(3..1631)
                     /locus_tag="ctg103_1"
                     /transl_table=11
                     /translation="MNISYNWLKEYVNFDLTPDETAAALTSIGLETGGVEEVQTIKGGL
                     EGLVIGEVLTCEEHPNSDHLHITTVNLGDGEPVQIVCGAPNVAAGQKVVVATLGTKLYD
                     GDECFTIKKSKIRGVESTGMICAEDEIGIGTDHAGIIVLPAEAVPGTLAKDYYNIKSDY
                     VLEVDITPNRADACSHYGVARDLYAYLIQNGKQATLQRPSVDGFKVENHDLDIEVVVEN
                     SEACPHYAGVTVKGVTVKESPEWLQNKLRLIGVRPINNVVDITNYIVHAFGQPLHCFDA
                     GKIKGNEVIVKTLPEGTPFVTLDEVERKLNERDLMICNKEEAMCIAGVFGGLDSGSTEA
                     TTDVFIESAYFHPTWVRKTARRHGLNTDASFRFERGIDPNGVIYCLKLAALMVKELAGG
                     TISSEIKDVCVAAPQDFMVELSYEKVNSLIGKVIPVETIKSIVTSLEMKIMNETVDGLT
                     LAVPPYRVDVQRDCDVIEDILRIYGYNNVEIPTTLNSSLTTKGEHDKSNKLQNLVAEQL
                     VGCGFNEILNNSLTRAAYYDGLENYP"
     CDS             1771..1956
                     /locus_tag="ctg103_2"
                     /transl_table=11
                     /translation="MVGDKVAKNKGVFFVIFATYPYQNTTWLYSIKNNRPLDWSKSSGY
                     FHLTKRSFYSTQKMFF"
     CDS             complement(1953..3506)
                     /locus_tag="ctg103_3"
                     /transl_table=11
                     /translation="MAEQRRNSRNTKSTKVQPVNDYGRIQPQAPELEEAVLGALMIEKD
                     AYSLVSEILRPESFYEHRHQLIYAAITDLAVNQKPVDILTVKEQLSKRGELEEVGGPFY
                     ITQLSSKVASSAHIEYHARIIAQKSLARELITFTSNIQSKAFDETLDVDDLMQEAEGKL
                     FEISQQNMKKDYTQINPVIDEAYKLIQKAAARTDGLSGLESGFTKLDKMTSSWQNSDLI
                     IIAARPAMGKTAFVLSMAKNIAVDYRNPVALFSLEMSNVQLVNRLITNVCEIPSEKIKS
                     GQLASYEWQQLDYKLKDLLDAPLYVDDTPSLSVFELRTKARRLVREHGVRIIIIDYLQL
                     MNASGMAFGSRQEEVSTISRSLKGLAKELNIPIIALSQLNRGVESREGIDGKRPQLSDL
                     RESGAIEQDADMVCFIHRPEYYKIYQDDRGNDLRGMAEIVIAKHRNGAVGEVLLRFKGE
                     FTRFSNPEDDMVIPMPGEPAGAMLGSKLNAGAMPPPPPEPDFVPQGNNPFGATEGPLPF
                     "
     CDS             3705..4529
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GHMP_kinases_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GHMP_kinases_N"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg103_4"
                     /sec_met_domain="GHMP_kinases_C (E-value: 9.8e-10,
                     bitscore: 28.9, seeds: 112, tool: rule-based-clusters)"
                     /sec_met_domain="GHMP_kinases_N (E-value: 2e-10, bitscore:
                     31.0, seeds: 447, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MITFPNAKINLGLSITEKRPDGYHNLETVFYPVALEDALEIRTSP
                     EADKKFSLHQYGMEISGNPEDNLVVKAYLLLDKEFHLSPIEIHLYKHIPSGAGLGGGSS
                     DAAFMLKLLNEHFQLNLSEDQLEIYAATLGADCAFFIRNAPTFAEGIGNIFSPIPLSLK
                     GYQILIIKPDVFVSTREAFANIHPHHPEYSIKEAIKRPANEWKEILINDFEDSVFPQHP
                     VIGEIKAELYRQEAVYASMSGSGSSVYGLFEPEGTLPETDWGTNVFRFKGRL"
     CDS             complement(4762..5796)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GDP_Man_Dehyd"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg103_5"
                     /sec_met_domain="GDP_Man_Dehyd (E-value: 1.1e-52, bitscore:
                     169.5, seeds: 258, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKERILVTGGTGYIGSHTVVELQNSGYEVIIIDNLSNSSADVVDN
                     IEKVSGIRPAFEKLDCLDFAGLDAVFAKYKGIKAIIHFAASKAVGESVEKPLLYYRNNL
                     VSLINLLELMPKHGVEGIVFSSSCTVYGQPDELPVTEKAPIKKAESPYGNTKQINEEII
                     RDTIASGAPINAILLRYFNPIGAHPTALLGELPNGVPQNLIPYLTQTAMGIREKLSVFG
                     DDYDTPDGSCIRDFINVVDLAKAHVIAIRRILEQKQKEKVEVFNIGTGRGVSVLELING
                     FEKATGVKLNYQIVGRRAGDIEKVWANPDFANQELGWKAVETLEDTLRSAWNWQLKLRE
                     RGIQ"
     CDS             complement(6055..6372)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Rnf-Nqr"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg103_6"
                     /sec_met_domain="Rnf-Nqr (E-value: 2.3e-33, bitscore:
                     105.8, seeds: 650, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVEIFLKKVSPSLYQALGVFLPLITTNCCILGVAILVIQKDFDLL
                     TGVVYAFSTALGFGLALVLFAGLREQMTLVKIPKGMQGTPIALITAGLLAMAFMGFSGV
                     V"
     CDS             complement(6427..6627)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Rnf-Nqr"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg103_7"
                     /sec_met_domain="Rnf-Nqr (E-value: 5e-24, bitscore: 75.3,
                     seeds: 650, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEYILIFISAIFVNNIVLSQFLGICPFLGVSKKVETAMGMSAAVA
                     FVLTIATIVTFLIQKFVLDAF"
     CDS             complement(6650..7216)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Rnf-Nqr"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg103_8"
                     /sec_met_domain="Rnf-Nqr (E-value: 1.4e-70, bitscore:
                     226.9, seeds: 650, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MMNGIIKENPIFVLLLGMCPTLGTTSSAINGMGMGLATMFVLICS
                     NVVISSIKNLIPDMVRIPSFIVVIASFVTLLQMIMQAYVPDLYATLGLFIPLIVVNCIV
                     LGRAEAFAAKNNPLASMFDGIGMGFGFTIALTLLGAVREFLGTGKIFNLTILPEEYGML
                     IFVLAPGAFIALGYLIAIINSLKKA"
     CDS             complement(7252..7935)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: FMN_bind"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg103_9"
                     /sec_met_domain="FMN_bind (E-value: 1.1e-23, bitscore:
                     73.8, seeds: 891, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLLVLTGVTAVSVALLAYVNELTKGPIAEANAKTLNEALKKVLPE
                     YTNNPVAESDTVFSEKDGKKIVDFIIYPAKNGEKWVGSAVEAKSMGFGGELKVLVGFDA
                     EGKIYNYSLLAHAETPGLGSKADKWFGAYDPAKNEKPVSHEESAKSILGMNPGETPLAV
                     TKDMNGQVDAITASTITSRAFLNAVNAAYQAYKGGEVDTNSGASQKNEPAVAPEGEAAA
                     NDTNN"
     CDS             complement(7962..8954)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: NQR2_RnfD_RnfE"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg103_10"
                     /sec_met_domain="NQR2_RnfD_RnfE (E-value: 7.2e-121,
                     bitscore: 393.1, seeds: 472, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MENKLIVSLSPHVHGGDSVQKNMYGVLIALIPAFLVSLYFFGLGA
                     LIVTATSVAACLFFEWAIVKFLMKKPATTICDGSAVITGVLLAFNLPSNLPIWIIILGA
                     LFAIGVGKMSFGGLGCNPFNPALAGRVFLLLSFPVQMTTWPVVGQLTSYMDATTGATPL
                     ALMKQAVHGDASALSQIPDALTLFIGQNGGCIGEVSALALLLGLVYMLWKKIITWHIPV
                     SIIVTVFVFAGIMHMVDPEKYVSPVLQLLSGGLMLGAVFMATDYVTSPMSKKGMLIYGV
                     CIGLLTVVIRLFGAYPEGMSFAILIMNAFTPLINTYCKPKRFGEVAKKK"
     CDS             complement(8961..10298)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: RnfC_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: SLBB"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Complex1_51K"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_10"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg103_11"
                     /sec_met_domain="Fer4_10 (E-value: 1.6e-09, bitscore: 28.0,
                     seeds: 59, tool: rule-based-clusters)"
                     /sec_met_domain="SLBB (E-value: 9.3e-17, bitscore: 50.9,
                     seeds: 67, tool: rule-based-clusters)"
                     /sec_met_domain="Complex1_51K (E-value: 3.3e-51, bitscore:
                     163.3, seeds: 88, tool: rule-based-clusters)"
                     /sec_met_domain="RnfC_N (E-value: 2.1e-30, bitscore: 94.9,
                     seeds: 53, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 3.2e-06, bitscore: 17.7,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLKTFSIGGVHPHENKLSAHQPIITAEVPAKAVILLGQHIGAPAK
                     PIVAKGDMVKVGTKIAEPAGFVSAAIHSSVSGKVAKIDTVVDASGYAKPAIFIDVEGDE
                     WEETIDRSKTLVKECELSSEEIVKKIADAGIVGLGGACFPTQVKLCPPPSFKAECVIIN
                     AVECEPYLTADHQLMLEHAEEVMVGVSILMKAVKVNKAFIGIENNKPDAIELMTKVASS
                     YAGIEVVPLKVKYPQGGEKQLIDAITKRQVASGALPISTGAVVQNVGTAFAVYEAVQKN
                     KPLFERVITVTGKSVAKPSNFLARIGTPMKQLIDACGGLPEDTGKVIGGGPMMGKALVN
                     IEVPTAKGSSGILIMNQKEAKRGEAQTCIRCAKCVSACPMGLEPYLLGALSENGDFETM
                     EKERIMDCIECGSCQFTCPANRPLLDYCRLGKGKVGAMIRARQAKK"
     CDS             complement(10323..11204)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: FeS"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Fer4"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_7"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_6"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_17"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1016:4Fe-4S dicluster domain (Score: 38.6; E-value:
                     4e-12)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg103_12"
                     /sec_met_domain="Fer4_7 (E-value: 1e-12, bitscore: 38.6,
                     seeds: 208, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4 (E-value: 3.5e-09, bitscore: 26.4,
                     seeds: 528, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_2 (E-value: 7.2e-09, bitscore: 25.6,
                     seeds: 214, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_6 (E-value: 3.4e-09, bitscore: 26.7,
                     seeds: 134, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_17 (E-value: 1.2e-08, bitscore: 25.6,
                     seeds: 82, tool: rule-based-clusters)"
                     /sec_met_domain="FeS (E-value: 3e-11, bitscore: 33.0,
                     seeds: 364, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 4e-06, bitscore: 17.4,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNLILIAVISLGAIALVLAAILYVASKKFAVYEDPRIAQVGEVLP
                     QANCGGCGYPGCSGFADACVKAGSLDGKFCPVGGQPVMAQIADILGLAATEAEPMVAVV
                     RCNGSCANRPRINQYDGAKSCAIAASLYGGETGCSYGCLGCGDCVAACQFDAIHMNPET
                     GLPEVDEAKCTACGACVKACPKAIIEIRPQGKKSRRVYISCVNKDKGAVARKACTVSCI
                     GCGKCVKTCPFEAITLENNLAYIDPNKCKSCRKCVEVCPQNTIIELNFPPRKPKAEEAP
                     KTVAAEAPKVTE"
     CDS             complement(11211..11636)
                     /locus_tag="ctg103_13"
                     /transl_table=11
                     /translation="MTNNTIKHLGIVENIQGSHLSVRIVQTSACAACSAKGHCSSADSK
                     DKVIDITDVTAASYQVGERVMVIGETSMGMMAVTLAFIIPFVLLIVSLFAWMALIGNEL
                     YAALLSLAVLIPYYFVLWLNKTRMKQHFSFTIKPINN"
     CDS             complement(11867..11959)
                     /locus_tag="ctg103_14"
                     /transl_table=11
                     /translation="MKKTWSVVLKVIIAVAGAIAGVLGVQAASL"
     CDS             complement(11995..12516)
                     /locus_tag="ctg103_15"
                     /transl_table=11
                     /translation="MSVIYKVVTRPSDPRVPNSPKKYYPHLITLGQSVNLKYIAQKMQG
                     YSSLSIGDIKSVIQNFVEKMKEQLLEGKSVNIEGLGVFMLTACSKGADAAKDVNAKSVD
                     SVRIFFQANKELRITKTATRADEKLDLISLDEYLKKLNASVTPNDPDDGENGGGGNEGG
                     GDEEAPDPTV"
     CDS             complement(12673..14226)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) CbiA"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg103_16"
                     /sec_met_domain="CbiA (E-value: 7.8e-11, bitscore: 32.3,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="RIGIISKELGSTEANLESFKRDAGITDLTSEAQIALAGNAEYEKK
                     SVENRTQISLVNDLRKYLRGNEYEVLPSNVGLQDAALIGAIERYNEMLIERKRLLRTST
                     ENNPTIVNLDTSIRAMKANVQATLEGTLQGLMITKESLDREASRYSRRISNAPGQERAY
                     VSIARQQEIKAGLYLMLLQKREENAIALAATANNAKIIDEAIADDIPVSPKRSMIYLIA
                     LVLGVGIPVGIIYLIELTKFKIEGRADVEKLTSVPVVGDIPLTDEKNDKNGSIAVFENK
                     NNLMSETFRNIRTNLQFMLNNDQKVILVTSTVSGEGKSFVSSNLAISLSLLGKKVVIVG
                     LDIRKPGLNKVFQLSNKERGITQYLSNPETDLMELVQPSDVNKNLFILPGGTVPPNPTE
                     LLARNGLDRAIETLKKNFDYVILDTAPIGMVTDTLLIGRIADLSVYVCRADYTHKAEYT
                     LINELSFEKKLPNLCTVINGVDLKKRKYGYYYGYGKYGKHYGYGKRYGYGYGYGQDTKR
                     "
ORIGIN
        1 gatggatagt tctccagacc gtcgtagtaa gcggcacgag tcagagaatt attcagtatt
       61 tcattgaagc cacagccaac caactgttct gcaaccagat tctgtaattt gtttgattta
      121 tcatgctcac ccttggttgt cagactggag ttcagcgtag tcgggatttc tacattatta
      181 tatccgtaga tacgtagaat atcttcgatc acatcgcaat cacgctgtac gtctacacga
      241 taaggaggaa cggctaatgt cagtccgtca actgtctcat tcatgatttt catttccagg
      301 ctggtaacaa tgctcttgat cgtttccacg ggaatcactt taccaatcag cgaatttact
      361 ttctcataag aaagttctac cataaagtct tgtggagctg caacgcaaac atccttaatt
      421 tcggatgaga tagtgccacc ggccagttct ttcaccatca gagcagccag tttcagacaa
      481 tagattactc cgttcggatc gatgccacgt tcgaaacgga aagaagcatc cgtattcaga
      541 ccgtgacgac gggcagtctt acgcacccat gtaggatgga aataagcgct ttcgataaat
      601 acatctgtcg tagcttccgt agaaccggaa tccagtccgc cgaatacacc ggcaatacac
      661 atcgcttctt ctttgttgca gatcatcaga tcgcgttcgt tcaacttgcg ttccacttca
      721 tccaatgtga cgaatggagt gccttccggc aatgtcttga caattacttc attgcctttt
      781 atctttccgg catcgaaaca atgcaatggc tgaccgaaag catgaacgat ataattagta
      841 atatccacta cattattaat aggacgtaca ccgatcaagc gcaatttatt ctgcaaccat
      901 tcggggcttt ccttcacagt aacgcctttc accgtaacgc cggcatagtg aggacaggct
      961 tcgctgtttt caaccactac ttcgatatcc aaatcatgat tttccacctt aaatccatct
     1021 acagatggac gttgcaaagt agcctgcttg ccattctgaa tcaggtaagc atacaagtcg
     1081 cgggccacac catagtgtga gcaagcgtct gcacggttag gagtaatatc tacttcgagt
     1141 acgtagtcac tcttgatatt ataatagtct ttggcgagag tacccggaac agcttcagcc
     1201 ggcaacacga tgattcctgc atgatcggta ccaataccga tttcgtcttc tgcacaaatc
     1261 atccctgtag attctacacc acggattttt gacttcttga tagtaaagca ttcatcaccg
     1321 tcataaagtt tggtacccaa agtggcaacc actactttct gtccggcagc tacattcgga
     1381 gcaccgcata caatctgtac aggttcgccg tctcccagat tgacggtagt gatatgcaaa
     1441 tggtcggaat tcggatgttc ttcgcaagtc agcacttcac cgattacgag tccttccaaa
     1501 ccacccttaa tggtttgcac ttcttctaca ccacctgttt ccaagccgat tgaggtcagc
     1561 gcagcagccg tttcatcggg ggtcaaatca aagttgacat actctttcag ccagttataa
     1621 gagatattca tataattaaa tttttattgt ttctcaaaaa gtttcgcaaa gttaataaga
     1681 tttttcggtt gacatagaac gatttgagag aaaaatgtca agagaagcta aactaacaag
     1741 gacctgactg tattattccc caataaattc atggttggtg acaaagtggc aaaaaacaaa
     1801 ggggtattct ttgtcatttt tgccacctat ccctatcaga atacaacttg gctatactct
     1861 ataaaaaata atcgaccgct cgattggagt aaatcgagcg gttattttca tctgactaag
     1921 cggtcattct attcaaccca aaagatgttt ttttagaaag gtaacggtcc ttccgttgca
     1981 ccgaacggat tatttccctg cggaacaaag tccggttccg gcggaggcgg aggcatagca
     2041 ccggcattca gtttagaccc cagcatggca cctgcaggtt cacccggcat cggtataacc
     2101 atatcatctt ccggattaga gaatcgtgta aactcacctt tgaatcggag caagacttca
     2161 cctaccgcac cattacgatg cttggctatc acaatttccg ccataccgcg caggtcgtta
     2221 ccacgatcat cctgataaat cttataatat tccggacggt gaataaaaca caccatatcg
     2281 gcatcctgct cgatggctcc ggattcacga aggtcactca actgagggcg tttaccgtca
     2341 ataccttcac gactctccac accacgattc aactgcgaca aggctataat gggaatgttc
     2401 aactcctttg ccaatccttt caacgaacgg gatatcgtac taacctcttc ctgacggcta
     2461 ccgaatgcca taccactcgc attcatcaac tgaaggtagt caataataat gattctcacc
     2521 ccatgttcac gcaccagacg acgtgctttg gtccggagtt caaacacaga caaagacgga
     2581 gtatcgtcca cataaagcgg agcatccagc aggtctttca gtttgtagtc caactgttgc
     2641 cactcatagc ttgccaattg tccacttttg atcttctcac tcggaatctc acaaacattg
     2701 gtgataagac ggttgaccaa ctggacgtta ctcatttcaa gagagaacaa cgctaccgga
     2761 ttccgataat caacagcaat attcttagcc atagaaagta cgaaagctgt cttacccatg
     2821 gcaggacggg cagcgattat aataaggtcg gagttctgcc aactggaggt cattttgtcc
     2881 agtttcgtaa atccactttc aagaccactc agaccgtccg ttcgtgcagc cgctttctga
     2941 atcagcttat acgcttcgtc aattaccgga ttaatctgcg tatagtcttt cttcatattc
     3001 tgctgggaaa tctcaaacag cttgccttcc gcctcctgca tcaagtcgtc cacatccagt
     3061 gtctcatcaa aagccttgct ttgaatatta ctggtaaacg ttatcaattc gcgcgccaac
     3121 gatttttgtg caataatacg ggcgtgatat tcgatatgtg cggaagaagc aaccttactg
     3181 ctcaactgag taatatagaa cggtccaccg acctcttcca actcacctct tttgctcaac
     3241 tgctctttga ccgtcagaat gtccaccggc ttctgattaa cggcaagatc agtaatggca
     3301 gcataaatca actgatgacg atgctcataa aatgactccg ggcgaagaat ctcactcacc
     3361 agcgaataag catccttctc aatcattaaa gcacccaaca ccgcctcttc cagctccggt
     3421 gcctgaggtt ggatacgacc ataatcattg accggttgta ctttagttga ttttgtgtta
     3481 cgggaatttc ttctttgttc agccatctgc ttatatacaa ttttatgatt tacaatttat
     3541 gatccccggc ttttatacat agtaaaatcc gaaagggatg acaaagatag aatataataa
     3601 tgaagaaaag ataaggaaaa atgaagattt tagtaacttt gtcaccaata gcataaattc
     3661 gcaacccata atttaaaatt caaaaataat aattcagaac gaatatgatc actttcccaa
     3721 acgcaaaaat aaacctggga ctctctatta ccgagaagcg tccggacgga tatcacaacc
     3781 tcgaaaccgt attctacccc gtcgctctcg aagatgcgct ggaaatccgg accagccccg
     3841 aagcggacaa aaagttctcc ctgcatcagt acggaatgga gatatccggt aatccagaag
     3901 acaatttagt ggtgaaagca tatctgctat tagataaaga gtttcacctc tctcctatcg
     3961 agatccatct gtacaaacac attccttccg gtgccggact gggaggaggc tcatcagacg
     4021 cagctttcat gctgaaatta ctcaacgaac actttcagct gaatttatcc gaagatcagc
     4081 tggaaatata tgccgcaact ttgggagcag actgcgcttt ctttatcaga aacgccccga
     4141 cctttgccga aggaatcggc aacatattct cccccattcc actatcctta aaaggatatc
     4201 agattctgat catcaaaccg gatgtattcg tatcaacgcg ggaagctttc gccaatattc
     4261 accctcatca tcccgaatac tcgatcaaag aagcgatcaa acgcccggca aatgaatgga
     4321 aagagatatt aatcaatgat tttgaagaca gcgtattccc ccagcatccg gtgatcggag
     4381 aaattaaagc cgaactatac aggcaagagg ctgtttatgc ctctatgagc ggttccggtt
     4441 cttccgtata tggattgttc gagccggaag gaactttacc tgaaaccgat tggggaacta
     4501 acgtattccg ttttaaaggc aggctgtaaa ggagtaacaa aaaacggtac cacgactccc
     4561 gtcgtagtac cgtcacaaca caaacacaaa ataaaacacg acaaaactac tatgcaatca
     4621 tacctgtcta tgccggagag gcataagtac catttactca tattcacata ctcacaaaca
     4681 gatcaagctg attagcatct aataaacaaa tcgcatgaac gatttgttta aacttttatg
     4741 ttaattaaaa caaatatctt tttactgaat gcctctttca cggagtttca gctgccaatt
     4801 ccatgcagag cgtaaagtat cttctaatgt ttctaccgct ttccaaccca gttcctggtt
     4861 ggcaaaatcg gggttagccc ataccttttc aatatcacct gcgcgacggc ctacaatctg
     4921 ataattcagt ttaacgccag tagctttttc aaagccatta atcagttcca atactgaaac
     4981 accgcgtcct gtaccgatat tgaatacttc tactttttct ttctgttttt gctccaaaat
     5041 acggcggatt gcaatcacgt gtgctttagc caagtcaaca acgttgataa agtcacggat
     5101 acaagaaccg tcaggagtat cataatcgtc accgaataca cttagttttt cacggatacc
     5161 catcgctgtc tgagtcagat aaggaatcag gttttgagga acaccgttcg gaagttcacc
     5221 cagcaatgct gtaggatgtg cgccaatcgg attgaaataa cgcagcaaaa tagcattgat
     5281 cggggcaccg gaagctattg tatcacggat aatttcttca ttaatctgtt ttgtatttcc
     5341 ataaggagat tccgctttct tgatcggagc cttttccgtt acaggcaact catccggttg
     5401 accatatact gtacaggaag aagagaacac tatgccttct actccatgtt taggcattaa
     5461 ctccagaagg ttgattaaag aaaccaggtt gttacgataa taaagcaacg gcttctctac
     5521 cgactctcct actgctttgc ttgctgcgaa atgaataatc gctttaattc ctttatattt
     5581 ggcaaatacg gcatcaaggc cagcaaaatc aagacaatcc agtttctcaa aagctgggcg
     5641 gataccggat actttctcta tattgtcaac aacgtcagca ctcgaatttg ataaattatc
     5701 gataatgatt acttcgtatc cactgttttg tagttctaca acggtatgag acccaatata
     5761 gcctgttcct cccgttacta aaattctttc tttcatataa ttttaaaata tggttagttt
     5821 ttcggttttc agtttgtttg aggtacaaat gtatggaaat aaaatggaaa tgcaataaac
     5881 tatcgcaatt ttattcacag gaagatactt acgggacgat ttgagggcgt tttggtatga
     5941 taaaaaacat attcggtatg aacagatata aagaaaaagg ccggaaacaa actgcctgta
     6001 tgttgccata cgacagagtt tccagcctct ttatctaatt atcaacttag tcttttacac
     6061 gacgccagag aagcccatga atgccattgc cagcaaacct gcggtaatca aagcaatcgg
     6121 agtcccctgc attcctttcg gaatcttcac cagggtcatc tgctcacgca atccggcaaa
     6181 caataccagt gccagaccaa agccaagagc agtagagaat gcatatacaa cacctgtcag
     6241 cagatcaaag tctttctgga ttaccaggat tgccacaccg agaatacagc agttcgttgt
     6301 aatcaacggc aggaacaccc ccagtgcctg atacaaagaa ggagaaactt tcttcagaaa
     6361 aatttctacc atctgcacca gtccggcaat aaccagaata aaagtgattg tctgtaagta
     6421 ccccaatcag aaagcgtcca acacaaactt ctgaatcagg aatgtgacga tggtagcgat
     6481 agtcagcacg aaagcaactg ccgcactcat acccatcgct gtttccacct tcttggaaac
     6541 acccaggaac ggacagattc ccaggaactg cgacaacaca atgttgttta caaagattgc
     6601 cgagataaat atcaatatat attccatatt cttttcttat ttaatagagt taggctttct
     6661 tcagactatt aataatggca atcagataac ctaaagcgat aaaggcaccc ggagccaaaa
     6721 caaagatcag cattccgtat tcttccggca gaatggtcag attaaatatc ttacctgttc
     6781 cgaggaattc acgtacggca cccaacagag tcagggcaat ggtaaaacca aatcccatac
     6841 cgataccatc aaacatagaa gccagcggat tgttcttcgc tgcaaaagct tccgcacgtc
     6901 ccaatacgat acaatttact acgatcagcg gaatgaaaag accgagggta gcatacagat
     6961 cgggcacgta tgcttgcatt atcatctgca acagtgtcac gaatgacgcg atcaccacga
     7021 taaatgaagg gatgcgtacc atatccggaa tcagattctt gatagatgaa attaccacgt
     7081 tcgagcaaat caggacgaac atagtggcca gtcccatacc cataccgttg attgccgatg
     7141 atgtcgtacc cagtgtagga cacataccga gcaggagcac aaaaatagga ttctctttga
     7201 taatcccgtt catcattact ttaaaattat tcataactgt ctcctccttt cttagttatt
     7261 agtgtcatta gcagctgctt caccttccgg cgcaacagcc ggttcatttt tctgggaagc
     7321 tccggaattc gtatccacct caccgccttt atatgcctga taagcagcat tcaccgcatt
     7381 caggaaagca cgtgaagtga tagtagaagc cgtgatagca tctacctgtc cattcatgtc
     7441 tttggtcaca gccaatggag tctctcccgg attcatgccc aaaatagact ttgcactttc
     7501 ttcgtgagat accggttttt cgttctttgc aggatcataa gctccaaacc atttgtccgc
     7561 tttcgaaccc aatcccggag tttcagcgtg cgccaataaa gagtagttat aaatcttgcc
     7621 ttcagcatca aagcccacca gcactttcag ttcaccgcca aatcccattg acttggcttc
     7681 aacggcagaa cctacccact tttcgccatt cttggccgga tagataatga aatccacgat
     7741 tttctttccg tctttctcgc tgaaaacagt atcgctttcg gctaccggat tattggtata
     7801 ttcaggaagc acctttttca aggcctcgtt cagcgtcttt gcattcgctt cggcaatagg
     7861 gcctttcgtc agttcgttca cataagccag caacgctacg gaaacagctg taacgcccgt
     7921 aagtaccagc aacatattct ttaaagatga ttgtaacttt ttcatttctt cttcgctacc
     7981 tccccaaagc gtttaggttt acaataggtg ttaatcagcg gagtgaacgc attcataatc
     8041 aggatggcga atgacatacc ttcgggatat gcaccgaaca gacggataac caccgtcagc
     8101 agaccgatac aaacaccgta aatcagcata cctttcttgc tcatcggaga agtcacatag
     8161 tcggttgcca taaagacagc tcccagcatc agacctccgg agagtagttg caataccgga
     8221 gaaacatact tttcgggatc caccatatgc ataatgcctg caaatacaaa tacagtcaca
     8281 atgatagaaa ccggaatatg ccaggtgatg atctttttcc agagcatgta taccagtccg
     8341 agcaacagtg ccagcgcact tacttcaccg atacatccgc cgttctgtcc gataaacaga
     8401 gtcagcgcat caggtatctg gctcaaagca cttgcatcgc cgtgaacagc ctgtttcatc
     8461 aatgccagcg gagtagcacc ggtggtagcg tccatataag atgtcagctg acctactacc
     8521 ggccatgttg tcatctgcac cgggaaagaa agcaacagga atacacgtcc cgccaatgcc
     8581 gggttgaatg ggttgcagcc cagaccaccg aaagacatct tgcctacacc aattgcgaac
     8641 agtgcaccca gaatgataat ccagataggc agattggaag gtagattgaa tgccagcaac
     8701 acacctgtaa tgacagcaga accgtcacaa atggttgtag caggtttctt cattaagaat
     8761 ttaacgatcg cccattcgaa gaataaacag gctgctaccg aagtagccgt gacaatcaga
     8821 gcccccaggc cgaagaaata aagcgacacc agaaaagccg gaatcagtgc gatcagcacg
     8881 ccatacatat ttttctgtac gctgtctccg ccatgcacgt ggggtgatag tgatacgatt
     8941 aatttatttt ccatacttcg ttatttttta gcttgacgtg cacgaatcat agctcctact
     9001 ttacccttac ccaagcggca gtaatcaagc agcggacggt tggcaggaca agtgaactga
     9061 caggaaccgc actcgataca atccatgatt ctttcttttt ccattgtttc aaaatctccg
     9121 ttttcggaca aagctccgag caagtacggc tccagtccca tcggacaagc gctcacacac
     9181 tttgcgcaac ggatacaggt ttgtgcttca ccacgtttgg cttccttctg attcataatc
     9241 aggataccgg aactgccttt tgcggtagga acttcgatat tcaccagagc cttacccatc
     9301 atcggaccgc caccgatcac ttttcccgta tcctccggca gaccgccaca agcatcaatc
     9361 agctgtttca tcggtgtacc gatacgcgcc aggaagttgg aaggtttggc cacagacttg
     9421 ccagttacgg taatcacacg ctcaaacaac ggtttatttt tctgaacagc ttcataaaca
     9481 gcaaatgccg tacccacatt ctgcacaact gccccagtag agataggcag cgcaccactt
     9541 gccacctggc gtttggtaat cgcatcaatc aactgtttct caccaccctg aggatatttc
     9601 actttcaaag gaacaacttc gatgcctgca taactggaag caactttcgt catcagttca
     9661 atagcatccg gcttgttatt ctcaattccg ataaatgcct tatttacctt cacggctttc
     9721 atcagaatgg agacacctac catgacttct tccgcgtgtt ccagcatcag ctgatggtcg
     9781 gcagtcagat acggttcaca ttccaccgca ttgataatca cacattctgc cttgaacgaa
     9841 ggaggcggac aaagtttcac ctgtgtaggg aaacaagcac cacccaaacc tacgataccg
     9901 gcatcggcaa tcttcttcac gatttcttcg gacgaaagct cacattcttt gaccagtgtc
     9961 ttgctacggt caatggtttc ttcccattcg tcgccttcta catcaataaa gatagcaggt
    10021 tttgcataac cgctcgcatc gactactgta tcaatcttcg ccacttttcc actgacagaa
    10081 gagtgaattg ctgccgaaac gaagccggca ggttcggcaa tcttcgtgcc taccttcacc
    10141 atatcacctt ttgctactat cggtttggca ggtgcgccaa tgtgctgccc caacagaata
    10201 actgcctttg caggaacttc cgctgtgatg ataggttgat gtgccgacaa tttattttcg
    10261 tgtggatgaa ctccaccaat tgaaaatgtc tttaacatac aattctgtat tttattctgt
    10321 tattattctg ttaccttcgg agcttctgca gcaactgttt tcggtgcttc ttccgccttc
    10381 ggtttacgtg gagggaagtt cagctcgata atcgtgttct gcggacaaac ttccacgcac
    10441 ttacggcatg atttacactt gttcggatcg atgtaagcca ggttgttctc cagcgtaatg
    10501 gcttcgaacg gacaagtctt gacacactta ccacagccga tacagctcac tgtacaagcc
    10561 ttacgtgcta cggctccctt gtctttgttc acacaagaga tgtacacacg gcgtgatttc
    10621 ttgccttgcg gacgaatctc gatgatcgcc ttcggacaag ccttcacaca agcgccacaa
    10681 gctgtacatt tggcttcatc cacttccgga agtcccgttt caggattcat gtggatagcg
    10741 tcaaactggc aggcagccac acagtcgcca catccgaggc atccgtagct acaacctgtt
    10801 tctccaccat acaatgaagc ggcaatagcg caactcttcg caccgtcgta ttgattaata
    10861 cgcggacgat tggcacagct tccgttacat cttactactg ctaccatcgg ttcagcttca
    10921 gtagctgcca gtccgagaat atcagcaatt tgtgccatga caggctgacc gcctacaggg
    10981 cagaatttac catccagcga accggctttg acgcaagcat cggcaaatcc gctacaacca
    11041 ggatagccac atccaccaca gtttgcctgg ggcaacactt cccccacctg ggcaatccgc
    11101 gggtcttcat acacggcaaa tttcttggaa gctacataaa gaatagcggc cagcacgagc
    11161 gctatagctc ccaatgaaat cactgcaatc agaatcaaat tcataatgtt ttagttattt
    11221 attggtttta tagtaaatga aaaatgttgt ttcattcgcg ttttattgag ccacaatacg
    11281 aaataataag gaataagaac tgccagagaa agaagagccg catacagttc attccctatc
    11341 aacgccatcc atgcgaacag ggaaacaatc agaagtacaa aaggaattat gaatgcaagg
    11401 gttacagcca tcatgcccat cgacgtttcg ccgatcacca tcacccgctc tcctacctga
    11461 taggaagcag ctgtaacatc cgttatatct atgactttgt ctttactatc cgccgaagaa
    11521 cagtggcctt ttgcgctaca agccgcacaa gccgacgtct gaacgattct caccgacaga
    11581 tgagaaccct gtatgttttc cacaatacct agatgcttta tagtattatt cgtcattttg
    11641 caaactcaac attacaaatc gcggcaaatt taatcattat ttgtgaacta cgaagcattc
    11701 cctcattttt ttctacataa taaaatgtta ttttttgtgt tttcgttatc gcacacgaaa
    11761 aagtaacgcc aactatttga tattttagca tacaacaaag caggcgggaa agttcttccc
    11821 gcctgcctgt cttatctaac caattacttt atttactgaa tgctgcttac aatgatgcag
    11881 cctgtactcc cagtactccg gcaatcgcac cggctacagc aatgattact ttcaaaacta
    11941 cactccaagt tttcttcata gatttttcct cctttctttt ttaagctttt cagattatac
    12001 agtcggatcc ggagcttcct catctcctcc tccttcattt ccaccaccgc cattttcacc
    12061 atcatccgga tcattcggag tcacagaggc attcaacttc ttcagatatt catccaaact
    12121 gatcaaatcc agtttttcat ctgcacgggt agccgtcttc gtgatacgca gttccttatt
    12181 cgcctgaaag aagatgcgca cgctatccac acttttagca ttgacgtctt tcgccgcatc
    12241 cgcccctttc gagcaggcag tcagcataaa tacacccaag ccttcgatat tcacagactt
    12301 accttccaga agttgctctt tcattttctc cacaaaattc tgaatcacac tcttgatatc
    12361 accgatggat aaagaagaat agccctgcat tttctgcgca atatatttca gattgacaga
    12421 ctgacctaaa gtgatcagat gcggataata tttcttggga gaattgggaa cacgcgggtc
    12481 agatggtcgc gtaacaactt tgtaaattac actcataata cgttttttta aagattcaaa
    12541 ttcaagttat tttattcacg ttttgttgat caacaatgca aaggtgaggc ttttatttca
    12601 gataacaaaa agaaaagccc cttgcggggc tctttttctg agaaaagtta taattcatag
    12661 atattcagat atttatcttt ttgtatcttg gccatatcca tagccgtagc cataacgttt
    12721 gccatagccg taatgcttgc catacttacc gtagccgtag taataaccgt attttcgctt
    12781 cttcaggtct acaccgttga tgacagtaca aagattaggc agcttcttct caaaagacag
    12841 ttcattgatc aatgtatatt ccgccttatg agtgtagtca gcacggcaca cgtaaactga
    12901 caagtctgct atacggccga ttaataaggt atccgttacc atgccgatag gagcagtatc
    12961 aagaatgaca taatcgaagt tcttcttcaa ggtttcaatc gctctgtcca gaccgttacg
    13021 agccaacagt tctgttggat taggaggaac agtaccaccc ggaagaataa acagattctt
    13081 atttacatca gaaggctgaa caagttccat caaatccgtt tcaggattgg aaagatactg
    13141 agtaatacct ctctccttat tagagagctg gaatacttta ttcagtcctg gcttacgaat
    13201 atcgagcccg acaatcacca ctttctttcc caaaagagaa agactgattg ccaaattcga
    13261 cgagacgaat gattttcctt cgccactgac agtcgaggtc acaaggatca ccttctgatc
    13321 attattgagc ataaactgaa gattggtccg aatattacgg aaggtttcac tcatcagatt
    13381 attcttgttc tcgaagacag cgatagaacc attcttatca ttcttctcat cagttaatgg
    13441 aatatcaccg acaacaggca cacttgtcag tttctctaca tcggcacgac cttcgatctt
    13501 gaatttagtc agttcaatca aatagatgat accaaccgga attccaacac caagtaccaa
    13561 tgcaatcaaa tagatcatag agcgtttggg agataccgga atatcgtcag ctatcgcttc
    13621 atcaatgatc ttcgcattat tcgcagtagc agcaagcgca atagcattct cttcacgttt
    13681 ctgtaacaac atcagataca atccggcctt gatctcctgc tgacgggcaa tacttacata
    13741 agcacgttcc tgccccggag cgttgctgat acggcgggaa tagcgactcg cttcacggtc
    13801 aaggctctct ttggtaatca tcagtccctg caaggttcct tcaagagtag cctgcacatt
    13861 ggctttcatg gcacggatac tcgtatccaa gttaacaatc gtgggattat tctctgttga
    13921 cgtacgcagc aggcgtttac gttcaataag catctcgtta taacgttcaa tcgctccaat
    13981 caaggcagca tcttgtaaac ccacattact tggcaaaact tcatattcat tacctcgcaa
    14041 atacttacgc aagtcattca ccaagctgat ttgagtacga ttctccacac tcttcttttc
    14101 atattccgca ttaccggcca aggctatctg agcttcactc gtcaaatccg tgataccggc
    14161 atcacgcttg aaggactcca gattagcttc tgtactaccc aattcttttg agataatgcc
    14221 aatacgtt
//
