LOCUS       c00035_gnlPro..        14660 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|OILJIPIG_35.
ACCESSION   c00035_gnlPro..
VERSION     c00035_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-07 17:03:09
            Original ID  :: gnl|Prokka|OILJIPIG_35
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 14660
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..14660
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[3349:13365]"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and (minimum(2, [ACD1_car,
                     ACP_syn_III_C, AcetylCoA_hyd_C, AcetylCoA_hydro,
                     Acyl-CoA_dh_1, Acyl-CoA_dh_2, Butyrate_kinase,
                     CT_Propionyl_CoA1, CT_Propionyl_CoA2, CT_Propionyl_CoA3,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_2_CAF, CoA_trans_6_Glutaconate, E1_dh, ECH_1,
                     ECH_2, HBT, HBT_2, HCDH, HpaB, Ketoacyl-synt_C, Thiolase_C,
                     Thiolase_N, adh_short, adh_short_C2]) or FA_synthesis) and
                     not (PFL-like or PFL_6_pcresol or PFL_9_tma or Gly_radical
                     or Gly_430_pcre or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and not
                     (POR or POR_N))"
                     /neighbourhood="10000"
                     /product="TPP_fatty_acids"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      3350..13365
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and (minimum(2, [ACD1_car,
                     ACP_syn_III_C, AcetylCoA_hyd_C, AcetylCoA_hydro,
                     Acyl-CoA_dh_1, Acyl-CoA_dh_2, Butyrate_kinase,
                     CT_Propionyl_CoA1, CT_Propionyl_CoA2, CT_Propionyl_CoA3,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_2_CAF, CoA_trans_6_Glutaconate, E1_dh, ECH_1,
                     ECH_2, HBT, HBT_2, HCDH, HpaB, Ketoacyl-synt_C, Thiolase_C,
                     Thiolase_N, adh_short, adh_short_C2]) or FA_synthesis) and
                     not (PFL-like or PFL_6_pcresol or PFL_9_tma or Gly_radical
                     or Gly_430_pcre or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and not
                     (POR or POR_N))"
                     /neighbourhood="10000"
                     /product="TPP_fatty_acids"
                     /protocluster_number="1"
     cand_cluster    1..14660
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TPP_enzyme_C and (minimum(2, [ACD1_car,
                     ACP_syn_III_C, AcetylCoA_hyd_C, AcetylCoA_hydro,
                     Acyl-CoA_dh_1, Acyl-CoA_dh_2, Butyrate_kinase,
                     CT_Propionyl_CoA1, CT_Propionyl_CoA2, CT_Propionyl_CoA3,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_2_CAF, CoA_trans_6_Glutaconate, E1_dh, ECH_1,
                     ECH_2, HBT, HBT_2, HCDH, HpaB, Ketoacyl-synt_C, Thiolase_C,
                     Thiolase_N, adh_short, adh_short_C2]) or FA_synthesis) and
                     not (PFL-like or PFL_6_pcresol or PFL_9_tma or Gly_radical
                     or Gly_430_pcre or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and not
                     (POR or POR_N))"
                     /kind="single"
                     /product="TPP_fatty_acids"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..14660
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="TPP_fatty_acids"
                     /region_number="1"
                     /rules="(TPP_enzyme_C and (minimum(2, [ACD1_car,
                     ACP_syn_III_C, AcetylCoA_hyd_C, AcetylCoA_hydro,
                     Acyl-CoA_dh_1, Acyl-CoA_dh_2, Butyrate_kinase,
                     CT_Propionyl_CoA1, CT_Propionyl_CoA2, CT_Propionyl_CoA3,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_2_CAF, CoA_trans_6_Glutaconate, E1_dh, ECH_1,
                     ECH_2, HBT, HBT_2, HCDH, HpaB, Ketoacyl-synt_C, Thiolase_C,
                     Thiolase_N, adh_short, adh_short_C2]) or FA_synthesis) and
                     not (PFL-like or PFL_6_pcresol or PFL_9_tma or Gly_radical
                     or Gly_430_pcre or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and not
                     (POR or POR_N))"
                     /tool="gutsmash"
     CDS             complement(3..1979)
                     /locus_tag="ctg35_1"
                     /transl_table=11
                     /translation="MKFFKTTIAMATLLGCLPTSPAEVAFPGPAPGTASAEQSASGYTL
                     SNNILTAKFILRNGSLSFGGMTSKLGPVAKAGDELFIINLQDGRSLKSSELKAGNVKFV
                     SLQPNPKAFRLADRFPGKAVSATFQALNGTLRISWRAVLRDHSHYLRQELRLASTKPVQ
                     MKNIVAMQYDLAEGKAGAPSVSGNARGALIVNDLAFTALETPMGINTVGGAGNMEGGET
                     AIWSADKWSTASWTGNFNVPQELKKQYGEQVSSAEGPVSIDGKGACTITFQYKGGDKGN
                     NKLNLAGVQLLSSKGAVLDSDFHNGSTGDSNAGNTYTVQVPSRGNYILRYWAQTKSEPI
                     ASKGEITFSLPVRTLEEKQEPQADESRLAQGLWSRKTTLQPGEIWDVSSVLGIFAPGQK
                     RRSFLAYMERERVMPYRPFIHYNSWYELNINRNNDSDPAKRMTEEQCLAVLKDWQEQFF
                     QKRGMSIDAFVWDDGWDEFNSLWDFHKMFPQGFKRIDAAAGRQKAGIGTWLGPVGGYGA
                     SKGKRLAYWNVKHPDNKIGNFQLSNKEYFDAFVGRCSQMVKDYNMKYFKFDGISTHFHA
                     KGPGNEEDAEGIIRVLNALRKKKGDLYINCTVGTWASPFWFRYADSVWRQENDFGTIGA
                     GDNRDKWMTYGDRLVHEVFVQGSP"
     CDS             2457..3185
                     /locus_tag="ctg35_2"
                     /transl_table=11
                     /translation="MAIAACCSVPALASPGSLEPSAGTSYAAGTATTTEGIALGKDMTF
                     GSLSQSALPGGFIPYGGNFYASNYTISLWLDASSLTEGTQTTLFGYYGTNAGQSYGTNA
                     LYLTSDAKFGMGDGNLNTSTGSFSQNRGDVSETPVVLEGGLLNVTLAVTGANQSQSVEV
                     YVNGSLFDTLSYNGNMNGNRTDIQSWINPNLTWGEIQWTDTKLSAEQIAGFAGLQVPEP
                     ASASLGILGLAVLMMRRRRS"
     CDS             3350..5080
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_fatty_acids: TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg35_3"
                     /sec_met_domain="TPP_enzyme_C (E-value: 2.1e-34, bitscore:
                     108.2, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MHRVADQIVEILEKAGVKRIYGIVGDSLNPVTDALRRRKTIEWIH
                     VRHEEVAAFAASAEAQLSGNLAVCCGSSGPGNLHLINGLFDAHRNHAPVLAIASHIPQS
                     QVGMEYFQATHPEQLFKECSAYAELVSEASQAPSILMSAIQHAWARRDVGVVVLPGDIA
                     DAPAEMKNLVHPPSYTRENVVPEHESVSLLARMLDDHRRITFFCGAGCAGAEDRVVRLA
                     HRLKAPIAYTWRGKDYFEHDNPLGIGMTGLLGWGDAYKAMHESDMLVLWGTDFPYFNFI
                     PTKPEIVQIDRRGEVLGRRCRLDLGICGDVSVTAEALLNMVQEKTDSGHLDAALKRHAR
                     DVKEMNAYMEGNDKESPIRPEQLTTALNRHAASDAVFTVDTGTPCIWSARFLCATPGRR
                     TLASFNHGSMANAMPMAIGAQMEYPERQVIALCGDGGLSMLLGDLITIVQYRLPVKIVV
                     YNNDCLDFIQLEMQAAGLIPWQINLNNPSFAAVADAVGIKGFLLDKSSQVDQMVDMFLN
                     YPGAALLDAHVDRDALALPPYISMGQAADFSLAMMKQTLAGEVKQVWNTLAGNRKLFKP
                     "
     CDS             complement(5135..6601)
                     /locus_tag="ctg35_4"
                     /transl_table=11
                     /translation="MAISDYIVTIGLEVHCQIKTKSKMFCSCETGFGFEPNTRVCPTCL
                     GLPGALPVLNEFAIERTLLTGLMLGCSSPEISQWDRKNYFYPDMAKNYQTSQLDLPLCL
                     GGEVPLYPWSYPNDVIKAGVPPFRTVKLTRIHLEEDAAKITHHANYSLIDYNRAGSALM
                     EIVSEPDIDTPEEAYAYLKSLQQILNYGDISDADMEKGQMRCDVNISLRPHGQKELGAK
                     VEMKNINSMSAVRRALHYEIQRQAEELDMGIPQIQSTRRWDDERGESVVMRTKEDAHDY
                     RYFPCPDLVPVRTAPLVEKVRGQIPELPQERQKRFMEGYGLSEYDANVLVGDLELARFF
                     EEAARGTASGKKIANWVINNISAVLNEKGMRPSECPVKPGAIRELIAIIDDGTVSNNQA
                     KDVFAKMWDEPALAAAQAAKLLGFEKADSSFLDGIVREVISANPDKVAEIQGGNEKLLN
                     WLTGQVMKAAKGKANPKIVTEALKKALSME"
     CDS             complement(6970..7701)
                     /locus_tag="ctg35_5"
                     /transl_table=11
                     /translation="MNDTAAAILKATAALRDGTEKLRFESPVHVTYNPLTYAWGPHEQY
                     VRTYGNGEKGHLFLGMNPGPFGMAQTGVPFGEVDAVVNWLHIRGEVGRPEHTHPKRPVE
                     GFGCPRSEVSGRRLWGLFAEAFGTAENFFRHNYVANYCPLIWMGATGANITPDKLPAEQ
                     RAAVDAVCMEHLLSLITILNPHTLVGVGAYATQKLRDAASRLPGKSFTIGTLLHPSPAS
                     PIANKLWPERPIQQLKELGIL"
     CDS             7830..8774
                     /locus_tag="ctg35_6"
                     /transl_table=11
                     /translation="MTSGGDAAGMNPAIKAAVDHARQLGMNPYVVYDGLEGLIDGKIKE
                     ATRELTNDMIYRGGTLLRSSRSKRFFDYEFRKQAYEHLKERNIDKLIIMGGDGSFRALN
                     DFFNDFEVPFAGIPATIDNDIAGTDYCLGVDTAQNVILDCIDSVRDTARSHHRAFVIET
                     MGRDCGYLAMTTALCSAADICIVPEIPYDLESIYKRLQPVINEEGSCIIAVVAEGTRVA
                     QYLTRWLTERAGMDTRLTVLGHVQRGGSPTARDRLMGTRFATRAVEALNNGDINQIMVY
                     HDGQYGYASLDSVAGQQYSVNQDIINLCRELSC"
     CDS             8906..9958
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GDP_Man_Dehyd"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg35_7"
                     /sec_met_domain="GDP_Man_Dehyd (E-value: 1.2e-98, bitscore:
                     320.2, seeds: 258, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKVIVTGGAGFIGSNLVRLLLERGHEVLNIDALTYAGNIHSLDGS
                     ADSPAYRFLHADVRDASLMRRTLREYAPDWVMHLAAESHVDRSIDDPGNFMTTNVMGTF
                     SMLQAALEYYRSLEGEKKERFRFHHISTDEVYGSLGKEGLFTESTPYRPHSPYSASKAS
                     SDHLVRAWHDTYGLPVLITNCSNNYGPCQFPEKLIPVVILKALGGEPIPVYGKGENVRD
                     WLYVGDHCEALLTVVSCGKPGETYNIGGNNEKTNLELVELLCSHLDELRPRPDGRSYRE
                     QISFVQDRPGHDLRYAIDASKIRRELGWTPRQDHSSGFRKTIQWYLDHEEWWRGILSGE
                     YRLERLGTNG"
     CDS             9968..10831
                     /locus_tag="ctg35_8"
                     /transl_table=11
                     /translation="MKGIVLAGGSGTRLHPVTLSVSKQLLPVYDKPMVYYPISVLMLAG
                     IREILVISTPRDLPLYRDLLGDGSRFGVSFEYREQPRPEGLAQAFIIGEEFIGKDSVAL
                     VLGDNIFYGRGLTEKLRRAAELTSGATIFGYQVHDPQRFGVVEFNEEGKAVSIEEKPLR
                     PKSDIAVTGLYFYDNRVVEIAKRIPKSSRGELEITSVNQEYLKQGLLRVEKLARGYTWL
                     DTGTHDTLLEASMFVRTLEHHQGFKVACLEEIAFNNGWISQETLRSQAGAMNNNGYGRY
                     LDELVK"
     CDS             complement(11049..11750)
                     /locus_tag="ctg35_9"
                     /transl_table=11
                     /translation="MNWMIYPAARAFIKVCSVLFGAGAAAAVLIHLFMPFFLRSPRTAA
                     PFLLLGTGAELLSILSLSFLMFWGVRVLLASRGSRITRNLSMLAFLPALYALLIPFAGM
                     PVPSQYTEMDRVWEAVLLLAAVTSFFSFPYTAGYGAAGRRLFLAWGIAAAGCGLQSALF
                     FLAVLLRQFLSTAVPSLAAPVAWLAVLLSCGLEIMLATPSAMQAQRLFKEVMSIASMPE
                     PIDPSMPGNRP"
     CDS             complement(11869..13365)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_fatty_acids: AcetylCoA_hydro"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_fatty_acids: AcetylCoA_hyd_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg35_10"
                     /sec_met_domain="AcetylCoA_hyd_C (E-value: 6.8e-47,
                     bitscore: 148.9, seeds: 181, tool: rule-based-clusters)"
                     /sec_met_domain="AcetylCoA_hydro (E-value: 4.8e-44,
                     bitscore: 140.4, seeds: 5, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSYKVLTPEEAASLIKHGHHIGLSGFTPAGTAKAVTAALAKIAEA
                     EHEKGNPFQVSVFTGASTGDSCDGILSRAKAIRYRAPYTTNVDFRKAVNNGEIAYNDIH
                     LSQMAQEVRYGFMGNVDIAIIEACEVTADGKIYLTAAGGIAPTICRLADKIIVELNAAH
                     SKSAMGLHDVYEPLDPPYRREISIFKPSDRIGKPYIQVDPKKIVGVVETNWPDEARSFA
                     AADPLTDKIGQNVADFLAADMKRGIIPSTFLPLQSGVGNIANAVLGSLGRDKTIPAFEM
                     YTEVIQNSVIGLIREGRVKFGSACSLTVTNDCLEGIYRDMDFFRDKLVLRPSEISNSPE
                     VIRRLGVISINTAIEADIYGNVNSTHIGGTKMMNGIGGSGDFTRNAYISIFTCPSVAKD
                     GKISAIVPMVSHHDHTEHDVNIIITEQGVADLRGKSPKERAQTIIENCVHPDYKNILWD
                     YLKLSDGKAQTPQSIRAALGMHAELARSGDMKNVDWAQYK"
     CDS             complement(13426..14205)
                     /locus_tag="ctg35_11"
                     /transl_table=11
                     /translation="MNSAASFSTPPEEEGPCGDWTYHEWAEAFSTNDLARTLPPGHIAV
                     CRVQTGGRGRFNRKWIGEEGGLWASFTVPLSAPEDTAADVHWGHLPLVAGLALFNMLRG
                     MGLDSVRLRWPNDLLAGKSKLAGILVERPAENMAVIGIGINVFNDVSSIAGEIKDPPAR
                     LADLVRDCPSLHAVMASLGSHLNQVLSVFSHGGVPALQEGLSRAWAGERPVSILTDDET
                     VRGIFTGIDDQGNPVLSLPAGTVRTIPAHLINRLLEE"
     CDS             complement(14243..14659)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) OAD_beta"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg35_12"
                     /sec_met_domain="OAD_beta (E-value: 1.3e-63, bitscore:
                     204.7, seeds: 229, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LRECKVTERLVHASQNELINIVTIFLGTSVGLTMQGDRFLQSETL
                     LIILLGIVAFGVATAGGVIAAKIMNLIWRKNPVNPLIGSAGVSAVPMAARVSHNVGQKY
                     DPSNYLLMHAMGPNVAGVIGTAVIAGYYIATLAK"
ORIGIN
        1 agcggggagc cctgcacaaa aacttcatgc accaggcggt cgccgtaggt catccatttg
       61 tcgcggttgt cgcccgctcc gatggtgccg aagtcattct cctgcctcca tacggaatcc
      121 gcataacgga accagaaggg ggatgcccag gttcctacag tgcagttgat gtaaagatcc
      181 ccctttttct tgcgcagggc gttcagcacg cggatgatgc cttccgcatc ctcctcgttg
      241 ccgggcccct tggcatggaa gtgggtgctg atgccgtcga atttgaagta cttcatattg
      301 tagtccttca ccatctggga acagcggccc acaaaggcgt caaaatattc cttgttggag
      361 agctggaaat tgccgatctt gttgtccgga tgcttcacgt tccagtaagc gagacgcttg
      421 cccttggagg ctccgtagcc ccccaccgga cccagccacg tgccgatgcc ggccttttgc
      481 ctgccggctg cggcgtcaat gcgcttgaag ccctgcggga acattttgtg gaaatcccac
      541 aggctgttga attcatccca gccgtcgtcc cagacgaagg cgtcaatgga catgccgcgc
      601 ttctggaaaa actgttcctg ccagtctttc aggacggcca ggcattgttc ttccgtcatg
      661 cgcttggcgg ggtccgaatc attgttgcgg ttgatgttca gttcatacca ggaattataa
      721 tggatgaagg ggcggtaggg catcacgcgt tcccgttcca tataggccag gaaggagcga
      781 cgtttctggc cgggggcaaa aattccgaga acggatgata cgtcccatat ttccccgggc
      841 tgcaaggtgg ttttacggct ccagagtccc tgggccagcc gggattcgtc cgcctggggt
      901 tcctgctttt cctccagcgt gcgcacgggc agggaaaagg tgatttcccc cttgctggca
      961 atcggttcgc tcttggtctg ggcccagtag cgcagaatgt aatttcccct ggagggaacc
     1021 tgtaccgtgt aagtgttgcc ggcattggaa tctccggtgc tgccgttgtg gaaatcagag
     1081 tcaagaacgg cccccttgga agagaggagc tgcacgccgg caaggttcag cttattgttg
     1141 cccttgtccc ctcccttata ctggaaagtg atggtacatg ctcctttgcc gtcaatggaa
     1201 accgggcctt ccgcactgga aacctgttct ccgtactgct ttttcagttc ctggggaaca
     1261 ttgaaatttc cggtccatga agctgtggac cacttgtccg cactccagat ggcggtttct
     1321 cccccttcca tatttccggc gcctcccacg gtattgatgc ccatgggagt ttccagggcg
     1381 gtgaacgcca ggtcattgac gatgagtgct cctctggcgt ttccggaaac ggagggtgcc
     1441 ccggctttcc cttctgccag gtcatattgc atcgctacga tgtttttcat ctggacgggc
     1501 ttcgtacttg ccaggcggag ttcctgcctc aggtaatggg aatggtccct gagcacggca
     1561 cgccaggaaa tgcgaagggt tccgttcaga gcctggaatg ttgcgctgac ggcttttccc
     1621 gggaagcggt cagccagcct gaaggccttg gggttgggct gaagggagac gaatttgacg
     1681 tttcccgctt tcagctcgga ggatttaagg ctccgtccgt cctgaagatt gatgatgaat
     1741 aattcatccc ctgccttggc gacggggccc agtttggaag tcattcctcc gaaggaaaga
     1801 cttccgttcc gaaggataaa tttggccgtc aggatgttat tggaaagagt atagccggaa
     1861 gcagattgtt ccgcgctggc tgttccgggt gcaggccccg gaaaggcgac ttctgcgggg
     1921 gatgtgggca ggcagcccag cagggttgcc atggcaatgg ttgtcttgaa aaatttcatg
     1981 atgaaataat attacagcta gcgggaggat aatttgggga aggctctttt tcaagaaaaa
     2041 ggtcctggaa atggaaggaa agaaaattaa tttttattga atatgaaaac attatgttgc
     2101 tttttttgat ggctgaggga aaacaaccgg attcccaatc cgaggtcaat ctaacatttc
     2161 aattatgaaa ctattattac aattttttct attttgcgaa aagggattgc tgttcctata
     2221 cagcaacttc agagccgcca caaaaaaatc tattctgcgt tttatttttt atattcataa
     2281 gtgatagaag gtaattatat tacatttttt agcggattga aaaagcttgt tctcatcttt
     2341 cctgtggggg agagaaaaag agcggattgg gaatccgata tacagagggc ggggaatatc
     2401 tctctgattg ctactcagtc catcattcac agaaaatgaa aaaaacatta gcattaatgg
     2461 ccattgcggc gtgttgttcc gttccggcgt tggcgtctcc cggctcttta gaaccatcgg
     2521 ccggaacgtc ttacgctgcc ggtacggcga cgacaactga aggtattgca ttgggaaaag
     2581 acatgacgtt tgggagtctc tcacagagtg cccttcctgg cggtttcatt ccttacggcg
     2641 gtaattttta tgcttccaat tacacgatct ccctctggct ggatgcctct tccttaacgg
     2701 aaggaaccca gaccacgctg tttgggtatt atggcaccaa tgcgggccaa agttacggga
     2761 caaatgcctt gtatctgacg tcagatgcca agtttggcat gggagatggg aacttgaata
     2821 cttctaccgg ctctttttcc caaaaccgtg gagacgtttc tgaaactccc gttgttttgg
     2881 agggaggtct tcttaacgtg actttggccg ttaccggcgc aaaccaaagc cagtctgtgg
     2941 aggtctatgt gaatggttcc ttgtttgaca cgttgtccta caacggcaac atgaacggaa
     3001 atcgcactga tatccaaagc tggattaatc ccaatcttac atggggtgaa attcagtgga
     3061 cggatacaaa actttccgcg gaacagattg ccggttttgc cggccttcag gttccggaac
     3121 cggcctcggc ttctctggga atcctgggcc tggccgttct gatgatgcgc cgccgccgtt
     3181 cctgacggtt ttccaccaga gaactggtaa attcataggc cgctgcctga aaaggcggcg
     3241 gccttatgat atcaggggaa atcctcaggc attttttccg gtgcggaaaa gatggagggg
     3301 atgacacata agaatgaatc cgttggaggt tggctggtgt ctaatctgca tgcacagggt
     3361 agccgatcag attgttgaaa ttttggagaa ggcgggagtt aagcggattt acggcattgt
     3421 gggggatagc ctgaaccccg ttacggacgc tttgaggagg aggaagacta ttgaatggat
     3481 tcatgtacgg catgaggaag tggcggcttt tgccgcgagc gcggaagccc agctgagcgg
     3541 gaatctggct gtatgctgcg gcagcagcgg ccccgggaac ctccatttga tcaacggcct
     3601 gtttgacgcc caccggaacc atgccccggt gctggccatt gcttcccaca tcccgcagag
     3661 ccaggtaggc atggaatatt tccaggccac gcatccggaa cagcttttta aggaatgcag
     3721 tgcatatgcg gaactggttt cggaagcttc ccaggccccg tccattttga tgtccgccat
     3781 tcagcacgcg tgggccaggc gcgacgtagg tgtcgtcgtc ttgcccggag acattgcgga
     3841 cgcccctgcg gagatgaaga atctggtgca tcctccttcc tacacgcggg agaatgttgt
     3901 tcctgagcat gaatccgtat cccttctggc acggatgctt gacgaccacc gccgcattac
     3961 tttcttctgc ggcgccggct gcgcgggagc ggaagacagg gtcgtccggc tcgcgcaccg
     4021 cctgaaagct ccgattgcct acacatggag gggaaaggat tattttgaac atgacaatcc
     4081 cctgggcatc ggcatgacgg ggctgcttgg atggggagat gcctacaagg ccatgcatga
     4141 aagcgacatg ctcgtgttgt gggggacgga tttcccctat ttcaatttca ttcccaccaa
     4201 acctgaaatc gtgcagattg acaggcgcgg tgaagtgctg ggccgccgct gccgcctgga
     4261 cctgggtatt tgcggggatg tttccgtcac ggcggaagct ctgctgaaca tggtgcagga
     4321 aaagacggat tccgggcatt tggacgccgc cctgaaacgc cacgccaggg acgtgaagga
     4381 gatgaacgcc tatatggaag gaaatgacaa ggagtctccc atccggccgg aacagctcac
     4441 gaccgccctg aacaggcatg cggcttccga cgccgtattt acggtagata ccggcacccc
     4501 ctgcatctgg agcgccaggt tcctgtgcgc cacgccgggc aggaggacgc tggcttcctt
     4561 caatcatggc tccatggcca atgccatgcc aatggctatt ggggcgcaga tggaataccc
     4621 cgaacggcag gtaattgccc tgtgtggaga tggcggcctg tccatgctgc tgggggatct
     4681 catcacgatt gtccagtaca ggctgccggt gaaaatcgtg gtgtataaca atgactgtct
     4741 ggatttcatc caattggaaa tgcaggcggc cgggctgatt ccgtggcaga tcaacctgaa
     4801 caacccctct tttgccgccg tggcggatgc cgtcggcatc aaggggtttt tattggacaa
     4861 atccagccag gtggaccaga tggtggacat gttcctgaat tatccgggcg ccgctctgct
     4921 ggacgcgcat gtggacaggg acgcccttgc cctgcctccc tacatcagta tgggccaggc
     4981 ggcggacttt tcccttgcca tgatgaagca gacgctggcc ggggaagtga agcaggtatg
     5041 gaacaccctg gccggaaaca ggaagctgtt caaaccgtga tgccctgcgg gcaaggagcc
     5101 ggcaccggca agggaagcgg ctctttgttt atggttactc catggaaagg gcttttttca
     5161 gcgcttccgt cacgattttc gggttggctt tgcctttggc ggccttcatg acctggccgg
     5221 taagccagtt caggagcttt tcattgcccc cctgtatttc cgccaccttg tccggattgg
     5281 cggaaatgac ttcccgcacg atgccgtcca gaaaagagga atccgccttt tcaaagccca
     5341 gcagcttggc ggcctgcgct gcggcgaggg ccggttcatc ccacattttg gcgaatacgt
     5401 ccttggcctg gttgttggaa acggtgccgt cgtcaataat ggcgatcagc tcccggatgg
     5461 caccgggttt caccgggcat tcagacgggc gcatgccttt ttcattcagc acggcggaaa
     5521 tgttgttaat cacccagttg gcgatttttt tgccgctggc ggttccccgc gccgcctctt
     5581 caaaaaagcg tgccagttcc aggtctccca ccagcacgtt ggcgtcgtac tcgctcaggc
     5641 cgtatccttc catgaagcgt ttctgccgtt cctgaggcag ttcgggaatc tgcccgcgca
     5701 ctttctccac cagcggggcc gtgcgtacgg gaactagatc cggacagggg aaataacggt
     5761 aatcgtgcgc gtcttccttg gttcgcatga cgacgctttc tccgcgttcg tcgtcccagc
     5821 ggcgggtgga ctggatttga ggaatgccca tgtccagttc ttccgcctgg cgctggattt
     5881 cataatgaag ggctctgcgg acggcggaca tggagttgat gttcttcatt tccaccttgg
     5941 cgcccaattc cttctgcccg tggggacgca gggaaatatt cacatcgcac cgcatctggc
     6001 ccttttccat gtccgcgtcg gagatatccc cgtaattcag aatctgctgg agagacttga
     6061 ggtaggcgta ggcttcttcc ggggtgtcga tgtccggctc ggaaacgatt tccatcaggg
     6121 cggaccccgc gcggttgtag tcgatcaggg aataattggc atgatgggta atcttcgccg
     6181 cgtcttcttc cagatggatg cgggtcagct tcacggtgcg gaaagggggg acgccggctt
     6241 tgatcacgtc attcggatag gaccaggggt acaggggcac ttcccctccc aggcacagcg
     6301 gaagatccag ctgggaggtc tggtaatttt tagccatgtc cggatagaaa taattcttgc
     6361 ggtcccattg ggaaatctcc gggctggaac atcccagcat caggccggtc agcagcgtgc
     6421 gttcaatggc gaactcattc aggacgggca gggcgcccgg cagccccagg caggtggggc
     6481 acacgcgcgt attgggttca aagccaaagc cggtctcgca ggagcagaac attttgctct
     6541 ttgtcttgat ctggcagtgg acttccaggc caatggtcac gatgtaatct gaaattgcca
     6601 taaattcgga acgcttgaag atcgcggaaa ctgtacggaa cccttttccc cctgtccagt
     6661 aaaaaggcct gcgggggaga gcggagggtt ttcagtctaa gaatgatgat tgatttggag
     6721 ggaggctgat ttttgtggtg gaagtgggga ggcgtttaag ttcttctccg tcccggtaga
     6781 tgccggcgtg cttttcttcc gtcaggaagg ccgtgtccct gggcaaatca agccagtaaa
     6841 gggggccgga tattccttca aaacgatgta gatttggagg agaacaagat gaactgccga
     6901 tttccggcct gtcgctctgg tgattccttc catgtcacgg agctttccac tctacctcct
     6961 ccgctctttt tataaaatgc ccagttcctt aagctgctgg atggggcgtt ccggccagag
     7021 cttgttggcg atggggctgg cggggcttgg gtggagcaac gtgccgatgg tgaagctttt
     7081 gccggggagc cgggaggcgg cgtcccgcag cttctgcgtg gcgtaggcac ccacacccac
     7141 cagcgtgtgg ggattcagga tggtgatgag ggaaagcagg tgttccatgc ataccgcgtc
     7201 cacggcggcg cgctgttccg ctggcagttt gtccggcgta atgttggctc cggtggctcc
     7261 catccagatc agcggacagt aattggccac gtaattgtga cggaagaagt tttccgcagt
     7321 gccgaaagct tccgcgaaaa gtccccagag gcggcggccg ctgacttccg acctggggca
     7381 gccgaagccc tccacgggac gtttggggtg ggtatgttcc ggccgcccga cttctccgcg
     7441 gatgtgcagc cagttgacga cggcgtccac ttccccgaag gggacgcctg tctgggccat
     7501 gccgaagggg ccgggattca tgcccaggaa cagatggccc ttttccccgt ttccgtaggt
     7561 gcgcacatac tgttcatgcg gcccccatgc ataggtgaga gggttgtagg taacatggac
     7621 cggggattcg aaccggagct tctccgtgcc gtcccggagg gcggccgtgg ctttcagaat
     7681 ggctgctgca gtgtcgttca tgcctccgca tcatgaagcg ttgccgttta ttgcgccagt
     7741 aaaaactccg cgcttgcatt atttgttccg cccggtaaca tctccccccg gacaagttaa
     7801 ccttattact tatgagtgga atagccatta tgacatctgg cggcgatgcc gccggaatga
     7861 acccggcgat caaggcggca gtggatcatg cccgccagct tgggatgaac ccgtacgttg
     7921 tttatgacgg cttggaaggg ctgatcgatg gaaaaatcaa ggaagccacc cgggaactga
     7981 ccaacgatat gatctacagg ggcggaactc tcctccgttc ctcacgatcc aagcgctttt
     8041 tcgactacga attccgcaag caggcctacg aacatctgaa ggaacgcaac atcgacaagc
     8101 tcatcatcat gggcggggac ggttccttcc gcgccctgaa cgactttttc aatgattttg
     8161 aagtgccttt tgccggtatt ccggccacga ttgacaacga cattgccggc acggactact
     8221 gcctgggcgt ggatacggcc cagaacgtga ttctggattg cattgattcc gttcgtgata
     8281 cggcccgttc ccatcaccgc gctttcgtga ttgaaacgat gggccgggac tgcggctatc
     8341 tggcgatgac caccgctctt tgcagcgcgg cggatatctg cattgtccct gaaattccgt
     8401 atgacctgga atccatttac aagcgcctcc agcctgtcat caatgaggaa ggaagctgca
     8461 tcattgccgt ggtggcggaa ggcacccgcg tggcgcagta cctgacccgc tggctgacgg
     8521 aacgcgccgg catggatacc cgcctgaccg tgctgggcca tgtgcagcgc ggcggttccc
     8581 ccaccgcccg tgaccgcctg atgggcaccc gttttgccac ccgcgccgtg gaagctctga
     8641 acaacgggga catcaaccag atcatggtgt atcatgacgg ccagtacggc tatgcctccc
     8701 tggattccgt agccgggcag cagtactccg tgaaccagga tatcatcaac ctttgccggg
     8761 agctgagctg ctagccgtct cagcggttac ggaacccgct ttttcccgcc catgccgcca
     8821 cgttcccgcg gcatgggcgg atttgttttg aaaaaaaacg ccgctgctgt atgatggcgc
     8881 cgcatctttc cctgaaaaca gtgctatgaa agttatcgtt acgggcggcg ccggattcat
     8941 cggctccaat ctggtcaggc tgctgctgga gcgcggccat gaagtcctga atattgacgc
     9001 cctgacctat gccggcaaca tccattcact ggacggctcg gcggattctc cggcataccg
     9061 ctttctgcac gccgacgtcc gggacgcttc cctgatgcgg cgcactttgc gggagtacgc
     9121 tccggactgg gtgatgcacc tggcggcgga atcccatgtg gaccgttcca ttgacgatcc
     9181 gggaaatttt atgaccacca acgtcatggg cactttttcc atgcttcagg ccgccctgga
     9241 atattaccgt tccctggagg gagagaaaaa ggagcgtttc cgctttcatc acatttccac
     9301 ggatgaagtg tacggctccc tgggaaagga aggcctgttc acggagtcca cgccgtatcg
     9361 cccccattcc ccgtattccg ccagcaaggc ctccagcgac cacctggtgc gcgcctggca
     9421 cgatacgtac ggtctgcccg tgctgatcac caactgttcc aacaattacg gcccctgcca
     9481 gttcccggaa aagctgatac ccgtcgttat cctgaaagcg ctgggcgggg aacccattcc
     9541 tgtatacggc aaaggggaaa acgtgcggga ctggctgtat gtgggggatc actgcgaggc
     9601 tctgttgacg gtcgtttcct gcggaaaacc gggggaaacg tacaacatcg gcggcaataa
     9661 cgagaaaacc aatctggagc tggtggagct gctgtgttcc catctggatg aactgcggcc
     9721 ccggccggac ggccggagct accgggagca aatctccttt gtgcaggaca ggccgggcca
     9781 tgacctgcgc tatgcgattg acgcttccaa aatacggagg gaattggggt ggactccgcg
     9841 ccaggaccat tcttccggat tcagaaagac cattcagtgg tatctggacc atgaggaatg
     9901 gtggcggggc atcctgtccg gggaataccg cctggaacgt cttggaacca atggctagga
     9961 atttgatatg aagggtattg ttctggccgg gggaagcggc acgcgtctgc atcccgttac
    10021 gctttccgtc agcaagcaat tgctgcccgt ttatgataag ccgatggttt attatcccat
    10081 ctccgtgctg atgctggccg ggatacggga aatccttgtt atttccacgc cccgggatct
    10141 gcccctgtac cgggatttgc tgggggacgg cagcaggttc ggcgtttcct ttgaatacag
    10201 ggaacaaccc aggccggagg ggctggctca ggcctttatt attggagagg agttcatagg
    10261 aaaggattcc gttgccctgg tgctggggga caatattttt tacgggcgtg gcctgacgga
    10321 gaagctgagg agggccgccg aactgacgag cggagcgacc attttcggtt accaggtgca
    10381 tgacccgcag cgtttcgggg tagtggaatt caatgaggag gggaaggcgg tttccattga
    10441 ggaaaaaccg ctcaggccca aatcggatat tgcggtgacg ggcctctatt tttacgacaa
    10501 ccgggtggtg gagatagcca aacggattcc caagtcttcc cgcggcgagt tggaaatcac
    10561 ctctgtgaat caggaatacc tgaagcaggg cctgttgcgc gtggaaaaac tggcgcgcgg
    10621 ttatacgtgg ctggatacgg gcacgcacga tacccttctg gaggcttcca tgttcgttcg
    10681 tactctggag caccaccagg ggttcaaggt agcctgcctg gaggagatag cctttaataa
    10741 cggctggatt tcccaggaaa cgctgcgctc ccaggccgga gccatgaata ataacggtta
    10801 tggccgttat ctggatgaat tggtgaaata gggctgtctg ccgccggagt ggaaacggga
    10861 ggggtgttcc tgcgaacccg cggctttccg gggtggggcg ggttgctttc cggcaatgct
    10921 ttccatacgg attccgttcc accggcggaa atttccggac ggctttttgc gcaaagccgt
    10981 aaaagccttt catgccgggg aatgagggtg ctcttccggc aggccggtaa aaacggaggg
    11041 gaggaaagtc agggacggtt gcccggcatg gaaggatcaa tcggttccgg catggatgct
    11101 atggacatga cctctttaaa caggcgctgc gcctgcatag cggaaggggt cgccagcatg
    11161 atttccaggc cgcaggacag aagaacggcc agccatgcaa caggcgctgc cagggaggga
    11221 actgcggtgg acaggaactg acgcaacagg acggcaagaa aaaacagggc gctctgcaaa
    11281 ccgcagcctg ccgccgcgat gccccaggcc aggaataatc tcctgcctgc ggcaccgtat
    11341 cccgccgtat aagggaagga aaagaaagaa gtgacggccg ccagaaggag gacggcctcc
    11401 caaaccctgt ccatttccgt atattgcgat gggacgggca tgcccgcaaa cggaatgagg
    11461 agggcgtaca gggcgggcag gaaggccagc atgctcagat ttcttgttat tctgcttccg
    11521 cgggaggcca gcagaactct gacgccccag aacatgagga aggacaggga aaggatggag
    11581 agcagttccg cccctgttcc caaaagcagg aagggcgcgg ctgttcgggg agagcggagg
    11641 aaaaaaggca tgaacagatg gatgaggact gccgctgctg cgcccgcgcc gaaaagaacg
    11701 gagcagactt tgatgaaagc cctggctgcc gggtaaatca tccagttcat ggtgaagaga
    11761 aggagtagag gggatgggaa aaaggaaaag gaccgctccc tttgcggaag cggtcctgag
    11821 gggttaacgt gaattcatgg atgccaatgc gaatgacggc atgcggaatt acttatactg
    11881 ggcccagtcg acattcttca tgtctccgct tctggccagt tcggcgtgca tgcccaaagc
    11941 ggccctgatg gattgcggtg tctgggcttt gccgtcggac agcttcaggt aatcccagag
    12001 gatgtttttg taatccgggt ggacgcagtt ttcaataatg gtctgggccc gttctttcgg
    12061 gctcttgccg cgcaggtccg cgaccccctg ctcggtaata atgatattga cgtcatgttc
    12121 cgtatggtca tggtgggaaa ccatggggac gatggcgctg atcttgccgt ccttggcaac
    12181 ggacgggcag gtgaaaatgg agatgtaggc gttgcgcgtg aagtcgccgg acccgccgat
    12241 gccgttcatc atcttcgtgc cgccaatgtg cgtggagttg acgttcccgt aaatgtcggc
    12301 ttcaatggcg gtgttgatgg agatgacgcc gagacggcgg ataacttccg ggctgttgga
    12361 tatttccgag ggacggagca ccagtttgtc gcggaaaaag tccatatccc tgtaaatgcc
    12421 ttccaggcag tcgttcgtca cggtcaggga gcaggcgctg ccgaatttta cgcggccctc
    12481 ccgaatcagg ccgatgacgg aattctggat gacttccgtg tacatctcga acgcgggaat
    12541 tgtcttgtcg cggcccaggg agcccagcac cgcgtttgcg atgttgccta cgccggactg
    12601 gagaggcagg aacgtggagg gaatgatgcc ccgtttcatg tcggcagcca ggaaatcggc
    12661 cacgttctgc ccgattttat cggtcagggg atccgctgcg gcgaaggaac gggcttcatc
    12721 cggccagttg gtttccacaa cgcccacaat ctttttcggg tcaacctgga tgtacggctt
    12781 gccgatgcgg tcgctgggtt tgaagatgga gatttcgcgg cggtagggag gatctagggg
    12841 ttcgtaaacg tcgtgcaggc ccatggcgct cttgctgtgg gcggcgttta attccacgat
    12901 aattttgtct gccaggcggc agatggtggg agcgatcccg cccgcggccg tcaggtaaat
    12961 tttgccgtcg gccgtgactt cacaggcttc aataatggcg atgtccacgt tgcccatgaa
    13021 cccgtagcgc acttcctggg ccatctggga caaatggatg tcattatagg cgatttcccc
    13081 gttgttcacc gccttgcgga aatcaacgtt ggtggtgtag ggagcgcggt agcggattgc
    13141 cttggcccgg gaaaggattc catcgcagga atcgccagtg gaagcaccgg tgaagacgct
    13201 cacctggaaa gggttcccct tctcatgttc cgcttctgcg atttttgcca gcgcagccgt
    13261 aacggccttg gccgttccgg cgggcgtgaa tccgctcagc ccaatatggt ggccatgctt
    13321 gatcaggctt gctgcttctt ctggtgtcag taccttgtaa ctcatgtcag tgatttttgt
    13381 tggatgaaaa aagaaagaaa ccccgtgtaa aacggagcgg caggctcatt cttcgaggag
    13441 cctgttgatc aggtgcgccg gaatggtgcg gacggtgccg gccggaaggg atagcacagg
    13501 attgccctga tcgtcaatcc ctgtaaaaat gccccggacg gtttcgtcat ccgtaagaat
    13561 ggaaaccggc ctttctccgg cccatgcccg ggacagaccc tcctgaaggg cggggacgcc
    13621 accgtgggaa aagacggaaa gaacctggtt caaatgactg cccagggaag ccatgacggc
    13681 gtgcagggaa gggcagtccc gaacaagatc cgccagcctt gccggagggt ccttgatttc
    13741 cccggcgatg gaggatacat cattgaaaac attgatgccg atgccgatga cggccatgtt
    13801 ctccgccggg cgttccacca gtattcccgc cagtttggat ttgcccgcca gcaggtcgtt
    13861 cggccagcgc aggcgcacgg aatccagccc catgccgcgg agcatgttga acagggccag
    13921 ccccgcaacc agaggcaaat ggccccagtg cacgtcggcc gctgtatcct caggagcgga
    13981 cagggggacg gtgaaggatg cccacaggcc gccttcctcc cctatccatt tgcggttgaa
    14041 cctgccgcgg cctcctgtct gaacacggca gacggcaata tgccccgggg ggagggtgcg
    14101 ggccagatca ttggtggaaa aagcctcagc ccattcatga taagtccagt cgccgcatgg
    14161 tccttcctcc tccggagggg tggaaaatga ggctgcggaa ttcatgggac gggccgaggc
    14221 cgggagtaat tttcaattct ggttatttcg ccagagtggc gatgtagtag cccgcgatga
    14281 ctgcggtgcc gatcacgcct gcaacgttcg ggcccatggc gtgcatgagc aggtagttgg
    14341 aggggtcgta cttctggccc acattgtggg agacgcgggc tgccatcggg acggcggaga
    14401 cgcctgcgga cccgatcagg gggttgaccg gattcttgcg ccagatgagg ttcataatct
    14461 tggcggcaat cactccgccc gctgttgcca cgccgaaggc gacgataccc agaaggatga
    14521 tcagcagcgt ttccgactgc aggaagcggt cgccctgcat cgtgagcccc acggaggttc
    14581 ccaggaagat ggtgacgatg ttgatgagtt cgttctggga ggcatgaacc aggcgttccg
    14641 tcaccttgca ttcgcgcagg
//
