LOCUS       c00048_gnlPro..         9466 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|LDIECPJP_48.
ACCESSION   c00048_gnlPro..
VERSION     c00048_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-05 14:32:01
            Original ID  :: gnl|Prokka|LDIECPJP_48
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 9466
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..9466
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[2:6959]"
                     /cutoff="10000"
                     /detection_rule="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /neighbourhood="10000"
                     /product="succinate2propionate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      3..6959
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /neighbourhood="10000"
                     /product="succinate2propionate"
                     /protocluster_number="1"
     cand_cluster    1..9466
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /kind="single"
                     /product="succinate2propionate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..9466
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="succinate2propionate"
                     /region_number="1"
                     /rules="(minimum(4, [AcetylCoA_hyd_C, AcetylCoA_hydro,
                     B12-binding, Biotin_lipoyl, Glyoxalase_4, HMGL-like,
                     MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma, PYC_OADA]) and
                     minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /tool="gutsmash"
     CDS             complement(3..1322)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: AcetylCoA_hydro"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: AcetylCoA_hyd_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg48_1"
                     /sec_met_domain="AcetylCoA_hyd_C (E-value: 8.3e-41,
                     bitscore: 128.9, seeds: 181, tool: rule-based-clusters)"
                     /sec_met_domain="AcetylCoA_hydro (E-value: 3e-44, bitscore:
                     140.8, seeds: 5, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSYKVLTPEEAASLIKHGHHIGLSGFTPAGTAKAVTAALAKIAEA
                     EHEKGNPFQVSVFTGASTGDSCDGILSRAKAIRYRAPYTTNVDFRKAVNNGEIAYNDIH
                     LSQMAQEVRYGFMGNVDIAIIEACEVTADGKIYLTAAGGIAPTICRLADKIIVELNAAH
                     SKSAMGLHDVYEPLDPPYRREISIFKPSDRIGKPYIQVDPKKIVGVVETNWPDEARSFA
                     AADPLTDKIGQNVADFLAADMKRGIIPSTFLPLQSGVGNIANAVLGALGRDKTIPAFEM
                     YTEVIQNSVIGLIREGRVKFGSACSLTVTNDCLEGIYRDMDFFRDKLVLRPSEISNSPE
                     VIRRLGVISINTAIEADIYGNVNSTHIGGTKMMNGIGGSGDFTRNAYISIFTCPSVAKD
                     GKISAIVPMVSHHDHTEHDVNIIITEQGVADLRGKSPKERA"
     CDS             complement(1384..2163)
                     /locus_tag="ctg48_2"
                     /transl_table=11
                     /translation="MNSAASFSTPPEEEGPCGDWTYHEWAEAFSTNDLARTLPPGHIAV
                     CRVQTGGRGRFNRKWIGEKGGLWASFTVPLSAPEDTAAGVHWGHLPLVAGLALFNMLRG
                     MGLDSVRLRWPNDLLAGKSKLAGILVERPAENMAVIGIGINVFNDVSSIAGEIKDPPAR
                     LADLVRDCPSLHAVMASLGSHLNQVLSVFSHGGVPSLQEGLSRAWAGERPVSILTDDET
                     VRGIFTGIDDQGNPVLSLPAGTVRTIPAHLINRLLEE"
     CDS             complement(2201..3865)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: OAD_beta"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg48_3"
                     /sec_met_domain="OAD_beta (E-value: 1.2e-159, bitscore:
                     520.2, seeds: 229, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSLFDSLITFLQGMGVFSLSWQMVGMWGIAILLLYLGVAKQYEPL
                     LMVPIAFGALIANIPDNGMLITQLNQQVISSNEQGEVTATSLNNVGYLRVHVAPLQQAP
                     SKVPANLTTPESRAQYQEIMQQPMQVYPGSQLTVSKIKSVRESQEKAKADAARLGDDSL
                     TVDPNLKDFQNVTEDNGNEPVFLLTNGEGTTVVRQQGVNYFDTSGNRIPVDLKTQKLEP
                     LVVSAAGKYVAVGQHTQELLVTSIHGGLYDWIGLGIKAEIFPPIIFLGVGALTDFGPLL
                     AAPRTLLLGAAAQVGVAATFFMALFMGFTPNESASIGIIGGADGPTSIFLTMKLAPHLL
                     GAVAVAAYTYMSLVPLIQPPIMALLTTKKERLIRMKSLRTVSKSEKLFFAVLVTIVTIL
                     LIPDASPLIGMLMLGNFLRECKVTERLVQASQNEIINIVTIFLGTSVGLTMQGDRFLQS
                     ETLLIILLGIVAFGVATAGGVIAAKIMNLIWRKNPVNPLIGSAGVSAVPMAARVSHNVG
                     QKYDPSNYLLMHAMGPNVAGVIGTAVIAGYYIATLAK"
     CDS             complement(3944..4345)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: Biotin_lipoyl"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1024:Biotin-requiring enzyme (Score: 58.8; E-value:
                     1.2e-18)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg48_4"
                     /sec_met_domain="Biotin_lipoyl (E-value: 2e-19, bitscore:
                     58.8, seeds: 40, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKLRITVDGKVFDVSVELLDQVSSTTAAPAPAPVAAPAPAASAP
                     VAAPAPAPAPAPAPAAASAGDVPSPLAGKVVSLDVAAGAPVKAGDQILTLEAMKMNTII
                     YAPASGTLTAFCVNPGDTVQEGQALAKIG"
     CDS             complement(4418..4870)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: OAD_gamma"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg48_5"
                     /sec_met_domain="OAD_gamma (E-value: 2.3e-10, bitscore:
                     30.5, seeds: 234, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLLTTLAFAFAQGIANVMNNLNYQVVGIMVVMLCLGGMAVILTVS
                     GSIAAAIQNRAKAKTAAPVAVPAAAPAAAGKPGMTPEMLAILSAAVDSAMTELTPEMVA
                     VISAAVDAGLDGMSHRIVEIKQSPGSGYAAAGRAEIFASHRIRPSR"
     CDS             complement(4892..6457)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: CT_Vparvula"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg48_6"
                     /sec_met_domain="CT_Vparvula (E-value: 9.2e-217, bitscore:
                     709.8, seeds: 132, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAIDPKLIDDLNSRRKKVTLSGGQEKIDKRHEKGEMTARDRMGYL
                     FEEGTFSEIGMHVRHNCHNFGMGKKEIPGDGVVSGFGLVDGRPVACAASDFLAQGGSLG
                     YMHAMKIADAQKYALKAGIPMVTVNDSGGARLQEGVAALSGYAQVFYNNVLASGVVPQI
                     SMILGPCAGGAAYSPALTDFIIMRNSGNAGMYITGPKVIEQVTYEKCTMDDIGSAAIHA
                     TVSGNVHFVADSDAHAMDILKRLLSFLPSNNTEEPPHKLDTPLDLSADEGMSDLIPGDN
                     RTPLDVQPIISRLVDNGDFLEVHKDFAKNVVVGFGRICGVVVGIIANQPNVKAGCLDID
                     SSDKAARFIRFCNAFNIPLVNLVDVPGFLPGKNQERGGIIRHGAKLIFAYSQATVPKVT
                     LIMRKAYGGAYIAMCCKDLGADAVFAWPGAEIAVMGAEGAVPVLYGRELKAVEDPAEKA
                     KRQGELLEEYREAFYNPYVAAGMGQITEVINPEETRAKIAFALRTLLNKKEVRPAKKHG
                     NIPL"
     CDS             complement(6489..6959)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: Glyoxalase_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg48_7"
                     /sec_met_domain="Glyoxalase_4 (E-value: 7.2e-26, bitscore:
                     80.1, seeds: 51, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MYCRPPPCIPYNHHTHMIQQIDHIGIAVKSLDATVPYYRDALGLG
                     EPHIEEVPTQKVRVAMFDVAGVHIELLEPTSPESAIAKAIEKKGEGIHHIAFKTNDIAG
                     NISQAKEAGLTVLNDPPVPGAHNTQVTFLHPKCTFGVLTEFCQHPGGCECGK"
     CDS             7077..8615
                     /locus_tag="ctg48_8"
                     /transl_table=11
                     /translation="MFKSGLAVLFLLASWFSAACAYELLPAHVAVIYNGKSELSRRMAR
                     EYARVRGVPEGNLVSLDCPMTSEISRKEYEDTIRVPLLETARKQRWWVPSGIASSPLMN
                     RKIFVLVLMADLPMKIRHETPAPLPGKGVNQMQTDRAAVDSELALLAVGGYERKSWQVN
                     PYFNKREDFVGSGLPSFLVCRLDGLTPDTCMRLVTEPANVEKKGLWGWAVVDRGGPYAQ
                     GDRWLDDVFERVREAGIPAYLDDWPQTLPEKFPLSRDTALYCGWYAGNANGPFSDPSFR
                     FRPGAIAMHLHSFSAADFKIPGRGWSSALLEKGAAVTVGNVYEPFLGACHRFDIFVDRL
                     LDGYTVAEASWMSMPVLSWQGVVFGDPLYRPYARMKDMDVKPTEEDRYFQGWWASSVQF
                     GDRWKDRSARLMESARKAPFSCLYEALALECLYRKEPFRAGELLSSALDGAADARTRAR
                     LLLEILMAERARGGNKAFLQRADSIRGLMSSSAFLPALEEWLARVAPPPAPPKK"
     CDS             8725..9072
                     /locus_tag="ctg48_9"
                     /transl_table=11
                     /translation="MNIINKIEQEQLKADVTPFNVGDTIKVHTRVIEGGKERIQIFQGI
                     VIAKRGSGINEAFTVRKISYGEGVERVFPLHTPRIAKIEVVNRGKVRRAKLHYLRGRIG
                     KDAMIVKSANR"
     CDS             complement(9189..9464)
                     /locus_tag="ctg48_10"
                     /transl_table=11
                     /translation="FGGHAENYRFLSPSRKSRTGQGLMECHALSSGIGFAYEIFRFLLH
                     SPEAIQARTEENPKNVFAPDGKQPPLSTFPTLEKRSHPHMAPGEIS"
ORIGIN
        1 tgggcccgtt ctttcgggct cttgccgcgc aggtccgcga ccccctgctc ggtaataatg
       61 atattgacgt catgttccgt atggtcatgg tgggaaacca tggggacgat ggcgctgatc
      121 ttgccgtcct tggcaacgga cgggcaggtg aaaatggaga tgtaggcgtt gcgcgtgaag
      181 tcgccggacc cgccgatgcc gttcatcatc ttcgtgccgc caatgtgcgt ggagttgacg
      241 ttcccgtaaa tgtcggcttc aatggcggtg ttgatggaga tgacgccgag acggcggata
      301 acttccgggc tgttggatat ttccgaggga cggagcacca gtttgtcgcg gaaaaagtcc
      361 atatccctgt aaatgccttc caggcagtcg ttcgtcacgg tcagggagca ggcgctgccg
      421 aatttcacgc ggccttcccg aatcaggccg atgacggaat tctggatgac ttccgtgtac
      481 atctcgaacg cgggaatcgt cttgtcgcgg cccagggcgc ccagcaccgc gtttgcgatg
      541 ttgcctacgc cggactggag aggcaggaac gtggagggaa tgatgccccg tttcatgtcg
      601 gcagccagga aatcggccac gttctgcccg attttatcgg tcaggggatc cgctgcggcg
      661 aaggaacggg cttcatccgg ccagttggtt tccacaacgc ccacaatctt tttcgggtca
      721 acctggatgt acggcttgcc gatgcggtcg ctgggtttga agatggaaat ttcgcggcgg
      781 tagggaggat ccaggggttc gtaaacgtcg tgcaggccca tggcgctctt gctgtgggcg
      841 gcgtttaatt ccacgataat tttgtctgcc aggcggcaga tggtgggagc gatcccgccc
      901 gcggccgtca ggtaaatttt gccgtcggcc gtgacttcac aggcttcaat aatggcgatg
      961 tccacgttgc ccatgaaccc gtagcgcact tcctgggcca tctgggacaa atggatgtca
     1021 ttataggcga tttccccgtt gttcaccgcc ttgcggaaat caacgttggt ggtgtaggga
     1081 gcgcggtagc ggattgcctt ggcccgggaa aggatcccgt cgcaggaatc gccggtggaa
     1141 gcaccggtga agacgctcac ctggaaaggg ttccccttct catgttccgc ttctgcgatt
     1201 tttgccagcg cagccgtaac ggccttggcc gttccggcgg gcgtgaatcc gctcagccca
     1261 atatggtggc catgcttgat caggcttgct gcttcttctg gtgtcagtac cttgtaactc
     1321 atgtcagtga tttttgttgg atgaaaaaag aaagaaaccc cgtgtaaaaa cggagcggta
     1381 ggctcattct tcgaggagcc tgttgatcag gtgcgccgga atggtgcgga cggtgccggc
     1441 cggaagggat agcacaggat tgccctgatc gtcaatccct gtaaaaatgc cccggacggt
     1501 ttcgtcatcc gtaagaatgg aaaccggcct ttctccggcc catgcccggg acagcccctc
     1561 ctgaagggag gggacgccgc cgtgggaaaa gacggaaaga acctggttca aatgactgcc
     1621 cagggaagcc atgacggcgt gcagggaagg gcagtcccga acaagatccg ccagccttgc
     1681 cggagggtcc ttgatttccc cggcgatgga ggatacatca ttgaaaacat tgatgccgat
     1741 gccgatgacg gccatgttct ccgccgggcg ttccaccagt attcccgcca gtttggattt
     1801 gcccgccagc aggtcgttcg gccagcgcag gcgcacggaa tccagcccca tgccgcggag
     1861 catgttgaac agggccagcc ccgcaaccag gggcaaatgg ccccagtgta cgccggccgc
     1921 tgtatcctca ggagcggaca gggggacggt gaaggatgcc cacaggccgc ctttctcccc
     1981 tatccatttg cggttgaacc tgccgcggcc tcctgtctga acacggcaga cggcaatatg
     2041 ccccgggggg agggtgcggg ccagatcatt ggtggaaaaa gcctcggccc attcatgata
     2101 agtccagtcg ccgcatggtc cttcctcctc cggaggggtg gaaaatgagg ctgcggaatt
     2161 catgggacgg gccgaggccg ggagtaattt tcaattctgg ttatttcgcc agagtggcga
     2221 tgtagtagcc cgcgatgact gcggtgccga tcacgcctgc aacgttcggg cccatggcgt
     2281 gcatgagcag gtagttggag gggtcgtact tctggcccac attgtgggag acgcgggctg
     2341 ccatcgggac ggcggagacg cctgcggacc cgatcagggg gttgaccgga ttcttgcgcc
     2401 agatgaggtt cataatcttg gcggcaatca ctccgcccgc tgttgccacg ccgaaggcga
     2461 cgatacccag aaggatgatc agcagcgttt ccgactgcag gaagcggtcg ccctgcatcg
     2521 tgagccccac ggaggttccc aggaagatgg tgacgatgtt gatgatttca ttctgggagg
     2581 cctgaaccag gcgttccgtc accttgcatt cgcgcaggaa gttgccaagc atcagcatgc
     2641 cgatcagcgg ggatgcgtcc ggaatcagca aaatggtgac aatggttacc agcacggcga
     2701 aaaacagttt ttcgctcttg ctgaccgttc gcagggattt catgcggatg aggcgttcct
     2761 tcttggtcgt cagcaacgcc atgatgggcg gctgtatcag cggaaccagg gacatgtacg
     2821 tgtatgcggc cacggccacg gcgcccagca ggtgcggggc cagcttcatc gtcaggaaga
     2881 tggaggtggg gccgtcagcg ccgccaatga tgccgatgga cgcggattca ttcggggtga
     2941 accccatgaa cagggccatg aagaacgtgg cggctacgcc cacctgggcc gctgcgccca
     3001 gaagcagggt gcgcggagcg gcaagcagcg ggccgaagtc cgtcagggct cctacgccca
     3061 gaaagatgat gggcgggaaa atttcagcct tgatgcccag cccgatccag tcatacaggc
     3121 ccccgtggat ggaggtgacc agcagttcct gggtatgctg gcctacggcc acgtatttgc
     3181 ctgcggctga aaccaccagg ggctccagct tctgggtttt cagatccacc ggaatccggt
     3241 tgccgctggt gtcaaagtaa ttgacgccct gctggcggac gacggtggtc ccttctccgt
     3301 tcgtgagcag gaagaccggt tcattgccgt tgtcttccgt cacgttctgg aaatccttca
     3361 ggttggggtc caccgtcagg ctgtcgtcgc ccaggcgggc cgcgtcagct tttgcttttt
     3421 cctgggattc ccgcacggac ttgatcttgg aaacggtcag ctggctgccg gggtaaactt
     3481 gcatgggctg ctgcatgatt tcctgatact gggcacggga ttcaggcgtg gtcagattgg
     3541 ccggcacctt ggagggagcc tgctgaagcg gagccacgtg aacgcgcagg taccccacgt
     3601 tgttcagaga cgtggcggtt acttccccct gttcattgga ggagatgacc tgctggttca
     3661 gctgggtgat gagcattccg ttatccggaa tgttggcaat gagggcgccg aaagcaatgg
     3721 gaaccatcag gagcggttcg tattgcttgg ctacacccag atacaggagg agaatggcaa
     3781 tgccccacat ccctaccatc tgccatgata gggagaagac gcccatcccc tgtaaaaagg
     3841 tgattaatga atcaaaaaga ctcataggga atatttttgt agcggtttat tatttgagtc
     3901 ggagcccggt actgttggcg tttccgggct gccgccgccg ggattaacca attttggcca
     3961 gtgcctgtcc ttcctgaacc gtgtcgcccg ggttcacgca gaaagcggtg agcgtgccgg
     4021 aggcgggagc gtagatgatg gtgttcatct tcatggcttc cagcgtcaga atctggtcac
     4081 cggccttcac gggtgcgcct gctgccacgt ccagggagac gaccttaccg gcaagcgggc
     4141 tgggaacgtc tcctgcgctg gcggcggccg gagccggagc aggtgcggga gccggggccg
     4201 gagcggccac gggtgcggaa gccgcaggag cgggagcggc cacaggtgcg ggggccggcg
     4261 ccgcagtggt ggaggacacc tggtccagaa gttctacgga tacgtcaaat actttgccgt
     4321 ctacggtgat gcgaagtttc ttcataatag tgtgtggtat gggatattaa gttaaatgat
     4381 tccgactggg cggggtaagg gtgaataatg cagtagttca gcgggaaggc cggatgcggt
     4441 gggaggcgaa aatttccgcc ctgcccgcgg ccgcatagcc ggaacccggg gattgcttga
     4501 tttccacgat gcggtggctc atgccgtcca ggcctgcgtc cacggcggcg gagatgacgg
     4561 ccaccatttc cggcgtaagc tccgtcatgg cggaatccac ggcggcggaa aggatggcga
     4621 gcatttccgg agtcatgccc ggtttgcccg ccgcagcggg agcggcggca ggcacggcta
     4681 cgggagcggc tgttttggct ttggccctgt tctgaatggc ggcggcgatg gagccgctga
     4741 cggtcagaat gacggccatg cctcccaggc acagcataac caccatgatg ccgacaacct
     4801 gatagttcag attgttcata acgttggcga tgccctgtgc gaaggcaaaa gcgagtgttg
     4861 taagtaacat ataaatccgt tgggatggat gttagagcgg aatgttgccg tgtttcttgg
     4921 ccgggcgcac ttccttcttg ttcagcaggg tgcgcagggc gaaggcgatt ttggcgcggg
     4981 tttcttccgg attgatgact tccgtaatct gtcccatgcc ggccgccaca tacgggttgt
     5041 aaaaggcttc ccggtattct tccagaagtt ctccctggcg cttggctttt tccgccgggt
     5101 cttccacagc cttcagttcg cggccgtaga gtaccgggac ggcgccttcc gcgcccataa
     5161 cggcaatttc cgcaccaggc caggcgaaga cggcgtcagc gcccaggtcc ttgcagcaca
     5221 tggcgatgta ggcgccgccg taggctttcc gcatgatcag ggtgactttg ggcaccgtgg
     5281 cctgggaata ggcgaagata agtttggcgc cgtggcggat aatgccgccc cgttcctggt
     5341 tcttgccggg caggaagccg ggcacgtcca ccaggttcac caacggaatg ttgaacgcgt
     5401 tgcagaaacg gatgaagcgc gcggccttgt cggaggagtc gatatccagg cagccggctt
     5461 tcacattggg ctggttggcg atgatgccga ccaccacgcc gcagatgcgg ccgaatccga
     5521 cgacgacatt tttggcgaag tccttgtgta cttccaggaa gtccccgttg tccaccagac
     5581 ggctgatgat gggctggacg tccagcggcg tgcggttgtc gccgggaatc aggtcgctca
     5641 tgccttcgtc agcgctcagg tccagcggag tgtccagttt gtggggcggt tcttccgtgt
     5701 tgttggaagg aaggaaggaa agaagcctct tcaggatgtc catggcgtgc gcgtcgctgt
     5761 ccgctacgaa atggacgttg ccggacacgg tggcgtgaat ggcggcggag ccgatgtcgt
     5821 ccatcgtgca tttttcatac gtgacctgtt caatcacttt gggaccggtg atgtacatgc
     5881 ccgcgttgcc ggaattgcgc atgatgatga agtccgtcag ggcgggggag taggccgcgc
     5941 cacccgcgca ggggcccagg atcatggaga tttgcggaac cacgccggag gcaagcacgt
     6001 tgttgtaaaa cacctgggcg tatccggaaa gggccgccac tccttcctgg aggcgcgcgc
     6061 cgccggagtc gttcacggtc accatcggga tgccggcttt cagagcatac ttctgggcat
     6121 ccgcaatttt catggcgtgc atgtagccga gggaaccgcc ctgggccagg aaatcggagg
     6181 ccgcgcaggc taccgggcgg ccgtccacca ggccgaaacc ggaaacgacg ccgtcgccgg
     6241 ggatttcctt cttacccatg ccgaagttgt ggcagttgtg gcgcacatgc atgccgattt
     6301 ccgagaaggt gccttcctca aagaggtacc ccatgcggtc gcgggctgtc atttcgccct
     6361 tttcatgtct cttgtcgatc ttttcctgac cgccgctgag ggtgaccttc ttgcggcggc
     6421 tgttcagatc gtcaatcaat ttgggatcaa tagccattgg tctagtggta tggtgaatag
     6481 ggagaatgtt acttgccgca ttcgcagccg ccggggtgct ggcagaattc ggtcaggacg
     6541 ccgaaggtgc acttgggatg caggaaggtg acctgcgtgt tgtgagcgcc ggggacgggc
     6601 gggtcgttca gcacggtaag gcctgcttcc ttggcctggg agatatttcc ggcgatgtca
     6661 ttggtcttga aagcgatgtg gtggatgcct tccccttttt tctcaatagc cttggcgata
     6721 gcgctttccg gagaggtggg ttcgagcagt tcgatgtgga ctccggcaac gtcaaacatg
     6781 gcgacgcgga ccttttgagt gggaacttcc tcaatgtggg gctctccgag cccgagcgca
     6841 tcgcggtaat aggggacggt ggcgtcaagg ctcttgacgg cgatgccgat atggtcaatt
     6901 tgctgaatca tatgcgtgtg atggttatag ggaatgcagg ggggaggcct gcaatacatc
     6961 aagagttatt aaagcgtatt tttttaggat gtgaagcgaa aagcggaaaa atggcgaatt
     7021 cgtggccgcc cctttcacct gcttgattgc cccggaagat gaggtatggt aggggcatgt
     7081 tcaagagtgg attagccgtg ttatttctgc tggcgtcgtg gttttccgcc gcgtgtgcct
     7141 atgagctgct gcccgctcat gtggccgtga tttataacgg aaaatccgag ctgagccgcc
     7201 gcatggccag ggagtatgcg cgggtgcgcg gcgttccgga agggaatctc gtttccctgg
     7261 attgccccat gaccagcgag atttcgcgga aggaatatga ggatacgatc cgcgtcccgc
     7321 tgctggagac ggcgcggaaa caacggtggt gggtgccttc cggcattgcg tcctccccct
     7381 tgatgaaccg gaagattttt gtgctggtgc tgatggcgga cctgccgatg aagatacggc
     7441 atgaaacgcc cgctcccctt cccgggaaag gcgtcaacca gatgcagacg gatcgcgctg
     7501 cggtggattc cgaattggct ctgctggcgg tgggcggtta tgaaaggaag tcctggcagg
     7561 tgaatcccta ttttaataaa agggaggatt ttgtgggttc cggccttcct tcgtttctgg
     7621 tatgccgcct ggacggactg acgcccgata cctgcatgcg gctggtgacg gaaccggcga
     7681 acgtggagaa aaaaggttta tgggggtggg ccgttgtgga ccggggcggt ccctatgccc
     7741 agggggaccg gtggctggac gacgtgttcg agcgcgtgag ggaggcgggc attcccgctt
     7801 atctggatga ctggccccag accttgccgg aaaaattccc cttgagccgg gatacggctc
     7861 tttactgtgg gtggtatgcg gggaatgcga acggaccgtt ttcggatcct tcgttccgtt
     7921 tccggcccgg ggcgatagcc atgcatctgc attccttcag cgccgccgat ttcaagatcc
     7981 ccggcagggg gtggagttcc gccctgctgg agaagggggc tgctgtgacg gtgggaaacg
     8041 tgtatgagcc gttcctgggc gcctgccacc gctttgatat ttttgtggac cgcctcctgg
     8101 acggctatac cgtggcggag gcttcctgga tgagcatgcc tgtgctgtcc tggcaggggg
     8161 tggtgttcgg agaccccctg taccgtccat acgcccgtat gaaggatatg gacgtgaagc
     8221 cgacggaaga agaccgttat ttccaggggt ggtgggcttc ctccgtgcag ttcggagacc
     8281 gctggaagga ccgttccgcg cgtttgatgg agtccgcccg gaaggcccct ttttcctgcc
     8341 tttatgaagc tctggcgctg gaatgcctgt accggaagga accgttccgc gccggagagc
     8401 tcctttcctc cgccctggac ggcgcggctg acgcccgcac ccgcgcgcgc ctgctgctgg
     8461 aaatcctgat ggcggaacgg gcccggggcg gcaacaaggc ctttctgcag cgggcggaca
     8521 gcatccgggg cctcatgtct tcctccgctt ttcttccggc gctggaggaa tggcttgcca
     8581 gggtggctcc gccgccggcc ccgccgaaaa aataaattaa ggacgtatgg caaatttgga
     8641 ttgcctttta ggggattatg gctcatattc tgcgtcccgt aagttttcct tttactgata
     8701 ttcaccagca atagataaca caagatgaac attatcaaca aaatcgagca agagcaactc
     8761 aaggcggatg tgaccccatt taacgtaggt gataccatca aggttcacac tcgtgttatt
     8821 gaaggcggca aggaacgtat ccagattttc cagggcattg tgatcgccaa gcgcggttcc
     8881 ggcatcaatg aagctttcac cgtccgcaaa atttcctacg gtgaaggcgt ggaacgcgta
     8941 ttccccctgc atactccccg cattgccaag attgaagtcg tgaaccgcgg caaagtccgc
     9001 cgcgccaaac ttcactatct gcgcggccgc atcggcaagg atgccatgat tgtgaagtct
     9061 gccaaccggt aatcggaaga attgctattt tgctggcccg gcccgccgtg aggcggcgcc
     9121 gggtttttta ttttccggag tattattttt cctgaatggg aaaggggtcc acagggacga
     9181 cagccgcttc aggatatttc cccgggagcc atatggggat gagagcgttt ttccagggtg
     9241 gggaaggtgg agaggggcgg ctgtttccca tccggagcaa atacgttttt cggattttcc
     9301 tccgtccggg cctggatggc ttccggagaa tggagcagaa accggaaaat ttcatacgcg
     9361 aagccaatcc cggaacttag cgcgtgacat tccatcaggc cctgtcccgt cctgcttttc
     9421 cgggaagggg aaaggaaacg gtagttttca gcatggcccc cgaagg
//
