LOCUS       c00021_gnlPro..        13689 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|ICOBNCGM_21.
ACCESSION   c00021_gnlPro..
VERSION     c00021_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-05 16:06:19
            Original ID  :: gnl|Prokka|ICOBNCGM_21
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 20161
            Orig. end    :: 33850
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..13689
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[30161:33651]"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..13490
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
     cand_cluster    1..13689
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /kind="single"
                     /product="Fumarate2succinate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..13689
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Fumarate2succinate"
                     /region_number="1"
                     /rules="(Succ_DH_flav_C and FAD_binding_2 and (Fer2_3 or
                     Fer4_7 or SucD_FumR))"
                     /tool="gutsmash"
     CDS             931..2076
                     /locus_tag="ctg21_25"
                     /transl_table=11
                     /translation="MPIKRLRPVLAIAADLPLGRLLTSFRNKDRRTIPWIFSLFHALES
                     QEDFDIHWITLSKAVSAPETIRMRNQTIHILPLGSMGRNILTAHFLTVRRIRKTLNDIQ
                     PDLLHVWGVEQAYALAGIAFRGKKLLSYQGALTAYCQRAPQAFLLHMQALWERMAVKHY
                     DLITCESPWACGRVAEIAPHARLSCMEYGVEPSFYHLARKPSPEPSCLFAGTIYELKGI
                     SYLVEAFTHPSLSHVQLFIAGNGALRERLEALSTPNIHWLGSISRAELQQHLSTAWFLV
                     HPTLGDCCPNIVKEARVMGLPVITTEEGGQTQYVQDGVSGYIVPVRNSAAIREAAQKLS
                     VSLDKTMSMGMERHQECRRLLDVKQTVTGCLSRYHTMLYPH"
     CDS             2076..2693
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Hexapep_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg21_26"
                     /sec_met_domain="Hexapep_2 (E-value: 3.9e-15, bitscore:
                     46.7, seeds: 55, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKLFLIHLLSGIGRLLLRLRGVRTGTGIILSGFPLIKKFPGASIT
                     IGNGVTIHSLTRMNPVLSHHTCLAALSHQASIILEDGCGISGATLVCVNGIRIGRHTLI
                     GADALILDNDMHYPRSGARWGSTLGKPEQGQPISIGEGCFIGARATILKGVTIGSGSVV
                     AAGAVVTRDVPPGCLAIGNPAVNKPLPERLKHPRETQKAICP"
     CDS             2740..3843
                     /locus_tag="ctg21_27"
                     /transl_table=11
                     /translation="MTPQNPTILLPSSREHWIDISRFLAACLIVCVHAPAFSFASLFQL
                     PVFNGRVAFFLILAGYFMGRNNSWNKAFKRGYTLLIPFLFWNIVISFLHPGIMNMGLPE
                     YLCNLAGFRSLFTPDFIPLSINGLTGEPFSPPTWFLRDIILCSLISPILLKLKYPVFVL
                     ILICFSTDWLQYPVPANKITLAPSTVSLFSLGLFLSSIKLAEVKHVYKNSFTPLVLLAV
                     GTGFLLSITNYLSVCQNNPEWNMHKILASYGVWNISWPAVHLNSLCPVFGALLLMALGI
                     WLEKKIPVARKLSNYAPACFLIFVLHYPLIMLIPSHIWKQSFFAPFVLIPAIIFLIVAF
                     YLFLRKFFPACLPYVANDRITHVPKKN"
     CDS             3824..4564
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Lipase_GDSL_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg21_28"
                     /sec_met_domain="Lipase_GDSL_2 (E-value: 7.8e-11, bitscore:
                     33.9, seeds: 1564, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFPKKIKACILFLLLTVPAALGAVWCAKHAYRYHLAVHPLPYSPE
                     QGALLEKHRQDKRNARLNPHAPVLFLGSSTMEFWLKEGKHSWETWFSPLGCLNLGTRSE
                     TTGNLLWRLNDGLTSPLAPRIIVLYSGVNNLGVQKSLGWTAFQGNVAIVKKIREIYSPE
                     TTAIIVIPPLIAQKGSRMETFRNCLLQHDFGENVHVLPLHFFLPGKDASLYTWDGLHLN
                     ALGYEAISPPLFRFLQQLLSRSSF"
     CDS             4648..5532
                     /locus_tag="ctg21_29"
                     /transl_table=11
                     /translation="MTLFLAGPTGSGKSAVAVELAEMLDAEIVSSDAYQVYRELPILTA
                     APSPADRERVPHHMVSIIPVQRNWNATEHYHRAMRCMEEIHARGKIAIVTGGSGLYFKF
                     LSHGLSEAPPGDAALRAAFANCSTEALYARLSSLDPEGAASTDASNRRYVERNLEIVLA
                     GGKPLSFWKRNWLTPPRGPGWVISRDVPELDERIAHRAARMMQEGAVEETASLGPCSAT
                     AERTLGLALIRSMLRGEISRENCQGQLALATRQYAKRQRTWLKREQWLRKLPASPSDSP
                     RALAERIMEELGH"
     CDS             complement(5529..6893)
                     /locus_tag="ctg21_30"
                     /transl_table=11
                     /translation="MGRGMMEGLMPYRDLFDQKGPFIFLIYGFSYALCGSYWLVFVLEV
                     FAVTASMIFCYKAALLFVSGKKAFIVSLLILYSMCSFHYYAGGGHPSEFILPFQFAAIY
                     GVCRLYRDPDRFVRTGVVFGAGIGMALLLKFNLAAFWFVPFLYVLYRARMTGKAWIFTG
                     SVGGTLLLMLTPCLWYFYSRGALLDLYEGYIVFNAGYGADAVSFKEMCRNYSQWVKRDI
                     MYPSMLMYIVGGAGVILSRMPAREKIYYTAAFLITCMGVQGNGKTHFNHYAQTLIPFAA
                     VGYLVVARMIHVEEVVSRKWRRWLFPLVVAGVMACTFLNCVDFSCRSRAREWMSAFALP
                     DTSDEPGGENACAVLGRHAVWFYCVNGLVPPIRTFTICASDKQGAERERMRQYQEIRRG
                     KIDYVVIAGEYFKPDNTESPSLRAMRDLLSTEYCRERSFFREVTNLDIYRRVKRD"
     CDS             7307..8014
                     /locus_tag="ctg21_31"
                     /transl_table=11
                     /translation="MNKLLSTLILSAGMSLSATAATSLLDSSIVGYSDFASQTADFGTL
                     KDSVSITSDDSNLTLSGITFNGYGANNRDVMSVTMVLDLSKINTPEAYTALFNAKNSSV
                     SWGVGLNTDRKLQGLWNNTSYNGPVVDTPLGTEGSLTISVVTGDLGTRIYFGDSATYYS
                     NSGLKFGNQQIDQILMDAGLAESIEQLYIHDSLLSQEQVGQLMSEIASIPEPATASLGL
                     LGLAALMMRRRRA"
     CDS             8443..8676
                     /locus_tag="ctg21_32"
                     /transl_table=11
                     /translation="MNLQKQQLLLRLFRYFKSRKGEPRFFNKRNICLLAAAGAYILTPD
                     EFLFDGIGRLGLLDDAAVILGAVLTVFFPDGD"
     CDS             complement(8710..9525)
                     /locus_tag="ctg21_33"
                     /transl_table=11
                     /translation="MMAFIEPHIHMVCRTTDEYRAMAQAGCLAVGEPAFWAGYDRSSAD
                     GFRDYFVQLTECEPARAAKFGMDHYTWLCINPKEAQDVAFARDVMKLIPEFIDRPNVLG
                     IGEIGLNRNTSHEMTIFEEHLDLAVRLNQLVLIHTPHLEDKLKGTVMILSALKNRPDLD
                     PCRVLVDHCEEHTFPLVKEAGYWAGLTLYPTSKLNPKRAADILELYGMDRVWANSAADW
                     GDSDPLALTALACELRRRGFSRQETERLLLENPETFMGQSPKFRKVSSR"
     CDS             complement(9528..9800)
                     /locus_tag="ctg21_34"
                     /transl_table=11
                     /translation="MKRSKKEVLDADFAAARAGVLDVAAFLDRVDRGEGEADFRYHALM
                     DVLPLLSASGPGRVRAILEALSYRDDTVPETAAAKAACGAPNLSK"
     CDS             10001..10702
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: SucD_FumR"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg21_35"
                     /sec_met_domain="SucD_FumR (E-value: 1.5e-13, bitscore:
                     42.0, seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNALVKTICTFVTSSIGRKIIVALTGLCLVLFLAGHLAGNLLIFG
                     GPEWINTYAHGLHSMPEAALWGIRAGLAVIFIIHVWLTIQLKLENHAAREPYVFKNTIK
                     ATLSSRYMIYTGLTVLVFLIYHLYQYTLRVGYDPAQFTTFISDGTVETFDVYKMIVTGF
                     SNVWCSAFYILAVLMLFSHLRHGVQSIFQTVGVDSRKIRPFYNFIAIAYGAIICLGFIS
                     VPVSVLLGIIK"
     CDS             10724..12682
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: FAD_binding_2"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Succ_DH_flav_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1027:FAD binding domain (Score: 176.1; E-value:
                     4.2e-54)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg21_36"
                     /sec_met_domain="FAD_binding_2 (E-value: 2.5e-54, bitscore:
                     176.1, seeds: 62, tool: rule-based-clusters)"
                     /sec_met_domain="Succ_DH_flav_C (E-value: 7e-38, bitscore:
                     120.8, seeds: 739, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MINFPVSDWMPDAKIPSGPIQDKWSKYKLESKLINPNNKRKYTVL
                     VVGSGLAGASAAATLAELGYNVKCFCYQDSPRRAHSIAAQGGINAAKNYQNDGDSVYRL
                     FYDTVKGGDFRAREANVYRLAEVSSNIIDQCVAQGVPFGREYGGLLDNRSFGGAQLKRT
                     FYARGQTGQQLLLGAYQALEKEVAKGHIEMFSRHEMMDLVLVDGEAKGIVTRNLVTGEI
                     KSYAGDTVLLCTGGYGNVFFLSTNAMGCNVTAAYKAYKRGAFFANPCFTQIHPTCIPVK
                     GDYQSKLTLMSESLRNSGRIWVPKSRETAEKIRKKEIKPSDVPEEERDYYLERKYPSFG
                     NLAPRDISSRAAKEACDDGRGVAVTGKGVFLDFADEIKRMGREWIDGQYGNLFDMYEEI
                     TDDDPHETPMMIYPASHYTMGGLWVDYNLMSNVKGLHVLGEANFSDHGANRLGASALMQ
                     GLSDGYFVIPATLPAYLTTTKPGAVTTAAPEFKAAEDEVKERINKLLNVKGTKTVDSFH
                     RELGLIMWEDCGMARTEESLTHAIERIPQLRKEFWENVRVTGTADGINAELEKACRVAD
                     FLEFAQLLCYDALNRQESCGAHFRVEYQLPDGEAKRNDDEYAYVAAWEYTGVDSLPVLH
                     KEPLTFENVHLAIRSYK"
     CDS             12660..13490
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Fer2_3"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_8"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052:Succinate dehydrogenase-2Fe-2S iron-sulfur
                     cluster binding domain (Score: -1.6; E-value: 9.2)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg21_37"
                     /sec_met_domain="Fer2_3 (E-value: 1.6e-23, bitscore: 74.1,
                     seeds: 38, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_8 (E-value: 5.1e-11, bitscore: 34.2,
                     seeds: 153, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 2.8e-06, bitscore: 19.0,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LPSAATSKDSQYINTQKKDYNMAKTLNLTLKVWRQENREAKGRIE
                     TYAAKDIPVDASFLEMLDIVNEGLVKEGKEPIHFDHDCREGICGMCSLTINGIPHGPER
                     QVTTCQLHMRKFKDGDTVWIEPFRAKAFPILRDLMVDRSALDRIIAAGGYIDVRTGSAP
                     NANNIAVEKVKADAAFDAAACIGCGACVASCKNASAMLFTSAKIAHLNLLPQGQPERSK
                     RVLAMMKQMEAEGFGNCTNQYECEAACPKGISVDNIARLNRDFMRANAKEGLCF"
ORIGIN
        1 cggcacggga ttcaggcatt ccgttttttc tccgctccca tggtgcagct accaatttcc
       61 gctctttttt ccgcttcaat taccctcctt tcttcggcct gaaaaaatgg ctctgctcct
      121 tttttcaagt acgcagggat atcctcaacg tatgccggaa atcaccgtta aaccgtctcg
      181 tttttctcga tccttacggg acactgttca agagctttga ttattactgc gcatccagaa
      241 gcaaacttgc ccattactcc tgcattccca acacattccc ggctctgaaa agaaccgctc
      301 cttttttccg ggaaaaatac ggactttcct ccgcccccgt ttttacctgc cctgccggcg
      361 ccagcatgag gaaacggcag cttctcttca tccgccatgt gaaacgctcc cgtctgcggc
      421 atatcatttt tctttttctg attccccagc acaatgccta cgcggaacaa atggaacaag
      481 ccatcgggga tgaccccaga ttcaggattc tctacaggct cccccgtttg gaagtagaag
      541 ccgccattat ggaaagcgat gccgttttcc tttactctta tcaggaacag cagcccctct
      601 ccattctgga ggcgatgtca tgcggcgttc cctggttcgc tccggacgca ggagctcttt
      661 ccaccctgga ggggggaatc gtcctgaaaa acacttcccc ctccgtgctg ggaaaagccg
      721 tggaatcgtt gacggacgaa aaaacacgca aactactggg gagtaaaggc cgccggcaat
      781 gggaagcctg tttcgccccc gacgcagtaa accaggaatg ggagcaactg cttttttcct
      841 ccatccgccc ggaaggaaag cctccgttcg catcttccat cgtccgggag catttaccca
      901 cctgctaacc ttgcctcctc tttccaatcc atgccgatca aacgcctccg tcccgtatta
      961 gccatagcag cggacctccc tctgggccgg ctgctgacgt ctttccgtaa taaggaccgg
     1021 cgtacgattc cctggatttt ttcccttttt catgctctgg aatctcagga agattttgac
     1081 atccactgga tcaccctcag caaagccgtt tctgccccgg aaaccatccg gatgcgcaac
     1141 cagaccatcc acattcttcc cctgggcagc atgggcagga atatcctgac ggcccatttc
     1201 ctgaccgtcc ggagaatacg caagaccctg aatgatatcc agccggacct cctgcacgta
     1261 tggggtgtgg agcaggctta cgctctggcg gggattgcct tccggggaaa gaagctcctt
     1321 tcctaccagg gagccctcac cgcctactgc cagcgcgctc cgcaggcctt cctcctccat
     1381 atgcaggccc tctgggaacg gatggccgtc aaacattatg atcttatcac gtgcgaatcc
     1441 ccctgggcgt gcggccgcgt tgcggaaatt gccccccatg cccgtctatc ctgcatggaa
     1501 tacggcgtgg aaccttcctt ttaccatctt gccagaaaac cttccccgga accttcctgc
     1561 ctctttgccg gaaccattta cgagttgaag ggcatttcct acctggtgga ggcctttacg
     1621 catccgtccc tttcccatgt ccagctgttc attgcgggca acggagccct cagggaaagg
     1681 ctggaagccc tgtccactcc caatatccac tggctgggca gcatttcccg cgcagaactt
     1741 cagcagcacc tctccacggc gtggttcctg gtgcatccca ccctggggga ttgctgcccc
     1801 aacatcgtga aggaggcaag agtcatgggc cttccggtaa tcaccacgga agaaggcgga
     1861 cagactcaat atgttcagga cggcgtatcc ggctatattg tccctgtccg caacagcgcc
     1921 gccatcaggg aggccgcgca gaaactttcc gtcagcctgg ataaaaccat gtccatggga
     1981 atggagcggc atcaggaatg ccgccgcctg ctggacgtaa agcagacagt aaccgggtgc
     2041 ctgtcacgtt atcataccat gctgtatcca cactgatgaa attattcctt atccatctgc
     2101 tttccgggat aggccgcctg ctgctcaggc tcaggggggt gcgcaccgga acaggcatca
     2161 ttctttccgg atttcccctc attaaaaaat tcccgggagc gtccatcacc atcggcaacg
     2221 gagtcaccat ccactccctg actcggatga atccggtact ttcccatcac acctgcctgg
     2281 ccgccctttc ccatcaggca agcatcattc tggaggacgg ctgcggcatc agcggagcca
     2341 ccctggtctg cgtcaacggc atccgcatcg gacgccacac gctgatagga gcagacgcgc
     2401 tgattctgga caacgacatg cactatcccc ggagcggcgc caggtgggga tcaaccctgg
     2461 ggaagcccga acagggacaa cccatttcca tcggggaagg atgcttcatc ggcgccaggg
     2521 ccaccatctt gaaaggagtc accatcggct ccggttccgt agtcgccgca ggagccgtcg
     2581 tcacccggga tgtgcctccc ggctgcctgg ccatcggaaa tcccgcagta aataaaccgc
     2641 tccccgaacg tctcaaacat ccccgggaaa cacaaaaagc catctgccct tgagcatttc
     2701 ccctgcctgc ctcagggggc tccaaaggca gactctttca tgacaccgca aaatcctaca
     2761 attttattac cctcatcccg ggaacattgg attgacatat cccgattcct cgcggcatgc
     2821 ctgattgtat gcgtccacgc gccggccttc tctttcgcca gcctgttcca gcttccggtt
     2881 ttcaacggcc gcgtggcatt tttcctgatt ctggcaggct atttcatggg ccggaataat
     2941 tcctggaaca aagcgttcaa acggggttat acgcttctca ttccctttct gttctggaat
     3001 atagtcatct ctttcctcca tccgggaatc atgaatatgg gactgccgga atacttatgc
     3061 aaccttgcag gcttccgctc ccttttcact cccgatttta ttcctctttc catcaatgga
     3121 ttgacgggag aacccttttc ccctcccaca tggtttttga gggatatcat tctctgttcc
     3181 ctcatttccc ccatcctgct gaaattgaaa tatccggttt ttgtcctgat cctgatctgc
     3241 ttcagcacgg actggctcca ataccccgtg ccggccaaca agattaccct tgctccatcc
     3301 accgtctccc tgttcagtct gggccttttc ctgtcttcca tcaaactggc tgaagtaaaa
     3361 cacgtttaca aaaattcctt tactcccctc gtcctgctcg ccgtaggaac cgggtttctg
     3421 ctcagcatca ccaattactt gagcgtttgc cagaataacc cggaatggaa catgcacaaa
     3481 atactggcat cctatggagt atggaatatc tcctggccgg ctgtccattt gaattccctc
     3541 tgcccagtct tcggggcgct tcttctcatg gcccttggaa tctggctgga aaagaaaatt
     3601 cccgttgcca gaaagctgtc caactatgct cccgcctgtt tcctgatatt cgttcttcat
     3661 tatcctttga tcatgctgat cccctcccac atctggaaac aatccttttt cgctcccttt
     3721 gtattaatac cggccatcat tttcctgatc gtcgcattct atcttttcct gagaaaattc
     3781 ttcccggcct gcctgcccta cgtcgccaac gaccgcatca cccatgttcc caaaaaaaat
     3841 taaggcctgt atcctctttc ttcttttaac cgttccggcc gcattaggcg ccgtctggtg
     3901 cgccaaacac gcctaccgct accatttggc tgtccatccc cttccctatt ccccggaaca
     3961 gggcgccctg ctggaaaaac accggcagga caaacgcaat gcccggctga atccccatgc
     4021 ccccgtgttg ttcctgggtt cctccaccat ggaattctgg ctgaaagaag ggaaacattc
     4081 ctgggaaacc tggttttccc ctctgggatg cctcaacctg ggaaccagga gcgagaccac
     4141 gggcaacctg ctctggcgcc tcaatgacgg cctgacaagc ccgctggcgc ccagaatcat
     4201 cgtcctgtat tcgggagtca acaatctggg agtacaaaaa agcctgggat ggacggcttt
     4261 tcagggaaac gtggccatcg tcaaaaaaat cagggagatt tacagcccgg aaacgaccgc
     4321 catcattgtc attcccccgc tcatcgcaca aaaagggtcg cgcatggaaa ccttcaggaa
     4381 ttgtctgctg caacacgact ttggagaaaa tgtccatgtc ctccccctcc atttcttcct
     4441 tccgggaaaa gacgccagcc tttatacttg ggacggcctc catctcaacg ccctgggata
     4501 tgaagccatt tcgcctccgc ttttccgctt cctccaacag cttttaagca ggagcagctt
     4561 ttagggcttc acaggaacaa caaactttat ccgccattac tccacgtgat gattgaatct
     4621 tctccacccc atcaggcaac acttcccatg accctgtttc tggcaggtcc caccggatcg
     4681 ggcaaatccg cggtagccgt ggaactggcg gagatgctgg acgcagaaat cgtcagttcc
     4741 gacgcttacc aggtgtaccg ggagctgccc atcctgacgg cggcgccttc cccggcagac
     4801 cgggaacggg tcccccacca catggtttcc atcattccgg tccaaaggaa ctggaatgcc
     4861 acggaacact accaccgcgc catgcgctgc atggaagaaa ttcacgcacg cggaaaaatc
     4921 gccatcgtca cgggcggttc cggcctgtac ttcaaattcc tctcccacgg cctgtcggaa
     4981 gcgccgccgg gggacgctgc tctccgcgcc gctttcgcga actgttccac ggaagcgcta
     5041 tacgccagac tctcttccct ggatccggaa ggagcggcct cgacggatgc ctccaaccgg
     5101 cgttatgtgg aacgcaatct ggaaatcgtc cttgccgggg ggaaacctct ttccttctgg
     5161 aagaggaact ggctgacccc gccgcgcggg cccggctggg tcatcagcag ggatgttcct
     5221 gaactggacg aaagaatagc ccaccgtgcc gcacgcatga tgcaggaggg ggccgtggag
     5281 gaaacggctt ccctcggccc atgctccgcc acagcggaac gtaccctggg cctggcgttg
     5341 atacgaagca tgctgcgcgg ggaaatctcc cgtgaaaact gccagggcca gctggccctc
     5401 gccacccggc aatacgccaa acggcagcgc acctggctga aacgcgaaca atggctccgg
     5461 aaacttccgg cttccccttc cgactctccc cgggctcttg cagaacgcat catggaagaa
     5521 ctggggcatt aatccctctt cacacggcgg taaatatcca agttcgtcac ttctctgaaa
     5581 aaggatcgtt cccggcaata ttccgtactt agcaaatccc gcatagccct cagggaggga
     5641 gattccgtgt tgtccggctt gaagtattct cccgctatca ccacatagtc tatctttccg
     5701 cggcggattt cctgatactg acgcatcctt tcccgttctg caccctgttt gtcggaagcg
     5761 caaatcgtaa acgtgcgtat gggcggcacc aaaccattga cacagtaaaa ccatacggca
     5821 tgccgcccaa ggactgcaca agcattctcc ccccccggtt catcactggt atctggaaga
     5881 gcaaaagcgg acatccattc gcgggcgcgg cttctgcatg aaaaatccac gcaattcagg
     5941 aaggtgcaag ccatcactcc cgcaacaacc agaggaaaaa gccatcggcg ccactttcgg
     6001 gaaacaacct cttccacatg gatcatcctg gccaccacca ggtatcccac agcagcgaag
     6061 ggaataagtg tctgggcgta atggttgaaa tgcgtctttc catttccctg gacgcccatg
     6121 caggtaatca gaaaagcggc tgtataataa atcttttccc tggcgggcat ccggcttaaa
     6181 atcacccccg ctcctcccac gatgtacatc aacatgctag gatacatgat atcccttttc
     6241 acccattggg aataattccg gcacatctcc ttgaacgata ccgcatcggc gccgtaaccg
     6301 gcattaaaaa caatgtatcc ttcatataaa tccagcaacg cgccgcggct gtaaaaatac
     6361 cagaggcagg gcgtcagcat caacaggagc gttcctccca cgcttcctgt aaaaatccat
     6421 gccttcccgg tcatccgcgc acgatacagg acatacagga agggaacgaa ccaaaaagcg
     6481 gccaagttga atttcaacag aagcgccatc ccgatgcccg cgccaaacac cacgcccgtt
     6541 cttacgaagc gatcgggatc ccgatacagg cggcacactc cataaatcgc ggcaaactgg
     6601 aaaggcagaa taaattcgga gggatgacct cctcctgcat aatagtggaa actgcacatg
     6661 gaataaagga tgagcagcga aacgataaac gctttttttc cagatacgaa gagaagggcc
     6721 gccttgtaac aaaagatcat ggaggccgtc actgcgaata cctcaagaac gaatacaagc
     6781 cagtaagaac cacacaaggc gtaggaaaag ccatatatca aaaaaatgaa gggccccttt
     6841 tgatcaaaca aatcccgata aggcatcaac ccttccatca ttccgcgtcc catgagatga
     6901 taaataatgg gatcacaact tacgggaatt tcataatagg gagacacata actggaataa
     6961 taacaaatca gaaatgagaa aatagaccac catgcaatac aacatccatt taccctatta
     7021 caacgaaaca tttttatatg ggtacggatt tggaattccc caatcggatt tggaatccgt
     7081 caagtaatga aaaagaggcc aaatcaatca tgaaaccaat gaataacaaa gactgacccg
     7141 tcatcttgac aaaaggacca gagatattaa aaaatcatta ttttcaatga attataaaca
     7201 caatatacta actcttaata tttttaattg cttgcggatt ccaaattcgt tattcaagca
     7261 caagtacata cattgaacct tgaatcattt tattaagata ctgaccatga ataaattatt
     7321 atccaccctg attctttcgg ccggcatgag cctgagcgct accgcggcta cctctctgct
     7381 ggatagctcc atcgtgggat attcggactt tgcctcccaa acggcggatt tcggcaccct
     7441 gaaagattcc gtttccatca cgtctgacga cagcaatctg acgttatccg ggataacctt
     7501 caacggatac ggtgccaaca accgcgacgt tatgtctgtg acgatggttc ttgacctgtc
     7561 caaaatcaac actccggagg cctataccgc tctgtttaac gccaaaaaca gcagtgtaag
     7621 ctggggcgtg ggcctgaaca cggaccggaa actccaggga ttatggaaca acacctcata
     7681 caacgggccc gtcgttgaca ccccgctggg cacggaaggt tccctgacca tttccgtagt
     7741 caccggagat cttggcaccc gcatctattt tggcgacagc gctacgtact attccaacag
     7801 cggcctgaaa ttcggcaacc agcaaattga tcagattctc atggacgcag gactggctga
     7861 atccatcgaa cagctctaca tccacgactc cctcctttcc caggaacaag ttggtcagct
     7921 gatgagtgaa atcgccagca ttccggaacc cgccacggct tccctgggcc tgctgggact
     7981 ggccgcgctg atgatgcgcc gccgcagggc ataagcctgt accgtccgcc tccctatatt
     8041 caaaggccgg ctcacaaaat cgtgagccgg ccttttcctt atccgttcaa acatctgccg
     8101 aaaaaacaga ggggaaaagc ttccatttgc tgcggcaacc tcacggccag cacttgacgg
     8161 aaaaatggca ttcagtctcc cccggtaggg tcatttcaag agcttccggc cccgccccac
     8221 ttccgtacac gccccttttt cccatgccgg gacagccgga accggagcat gcaaagcccg
     8281 gcttccctca gcatccggaa cagcccatcc tttcagcaat ccatttcccc gcacggtccg
     8341 gatcgctgcg gttccgtccg tcggcaacag actccttccc cgaaacaggg aaaaggagtg
     8401 ggaaaatggc tgagcttgaa cctttatccc ccgttcccgt ccatgaacct tcaaaaacag
     8461 cagctgctac tgcgcctgtt ccggtatttc aaaagcagaa aaggagaacc gcgttttttc
     8521 aacaaacgga atatatgcct tctggccgcc gccggcgcct acatcctgac tcccgacgaa
     8581 ttcctgtttg acggaatcgg caggctgggc cttctggatg acgcggcggt catcctgggc
     8641 gccgtcctca ccgtcttttt cccggacggg gactagaggg ccgtaccctc cgccgcgcct
     8701 cgggcggaat tagcgggacg acactttccg gaacttcggg gactgtccca tgaatgtctc
     8761 cggattttcc aggagaagac gttccgtttc ctgccgggaa aaaccgcgcc tgcgtagctc
     8821 gcaggccagg gccgtcagcg ccaggggatc ggaatccccc cagtccgccg cggaattggc
     8881 ccagacacgg tccattccgt acaattccag aatatccgcc gcccgcttgg gattcagctt
     8941 gctggtggga taaagggtca gcccggccca gtaaccggcc tccttcacca gcgggaaggt
     9001 atgttcctca cagtgatcca ccagcacgcg gcaagggtcc agatccggac ggtttttcag
     9061 ggcggaaaga atcattacgg tccccttaag cttgtcttcc agatggggag tgtgaatcag
     9121 cacaagctgg ttgaggcgca ccgccagatc cagatgctct tcaaaaatag tcatttcatg
     9181 ggaagtattc cggttcagcc ctatttcccc gatgccgagg acattgggcc ggtcaatgaa
     9241 ctccggaatc agtttcatca catcccgcgc gaaagccacg tcctgcgcct ccttgggatt
     9301 gatgcacagc catgtgtaat ggtccatgcc gaacttggcc gccctggcgg gttcgcattc
     9361 cgtaagctgt acgaaataat cccggaaacc gtccgcggac gaacggtcgt aaccggccca
     9421 gaacgccggt tcccctaccg ccaggcagcc ggcctgcgcc atggcccggt attcgtccgt
     9481 ggtgcggcac accatatgta tatgaggttc tatgaaagcc atcattctta tttgctgagg
     9541 ttcggggctc cgcaggccgc tttggctgcg gcggtttccg gcacggtgtc atccctgtag
     9601 gaaagggctt ccagaatggc ccggacgcgt ccggggccgg atgcggacaa gaggggaaga
     9661 acatccatca gggcatggta gcggaaatcc gcctcccctt ccccgcggtc cacccggtcc
     9721 agaaatgcgg ccacatccag aacgccggcg cgcgccgctg cgaaatccgc gtccagcacc
     9781 tcctttttac ttcttttcat gcacagacga tacgcctatg cggaaagcct cgtcaagccg
     9841 gaacaggcaa caaaatgata accattccaa actgataaac agcaacctct ttccccggtt
     9901 tttcaaaaat ccgaaaagcg ccggaaattc aagaagaggc ttgccatccg ggcttgaacc
     9961 gggcatcctg tgaagacgca tttatttcat tagagcgcct atgaatgcac tagtaaaaac
    10021 catatgtaca ttcgtgacat cctccatcgg ccgcaaaatc attgtggctc tgacggggtt
    10081 atgtttggtc ttgttccttg cgggacacct ggcaggcaac cttctcatct tcggaggccc
    10141 tgaatggatc aacacctacg cccacggcct gcactccatg ccggaagcag ccctctgggg
    10201 aatccgcgcg gggcttgcgg tgatcttcat catccacgtc tggctgacca tccagctgaa
    10261 gctggaaaac catgcggccc gcgaacccta cgtgttcaag aacaccatta aggcaacgct
    10321 ctcctcccgc tacatgatct ataccggttt gaccgtcctg gtgttcctga tctaccacct
    10381 gtaccagtac accctgcgcg tgggatacga ccccgcccag ttcaccacct tcatttccga
    10441 cggtacggtg gaaacctttg acgtgtacaa gatgatcgtg accggattct ccaacgtatg
    10501 gtgctccgcc ttctacatcc tggccgttct gatgctgttc agccatctgc gccacggggt
    10561 acagtccatc ttccagactg tgggcgtcga ttcccgcaaa atccggccct tctacaactt
    10621 tatcgccatc gcctacggcg cgattatctg cctgggcttc atctccgtgc cggtctcggt
    10681 tcttctgggt atcatcaaat aaccatcaac tcctctcaaa gtcatgatta attttcccgt
    10741 aagcgactgg atgccggatg ccaaaattcc ctccggccct attcaggaca aatggtccaa
    10801 gtacaaactt gagtccaaac tgatcaatcc gaacaacaag cgcaagtaca cggtgcttgt
    10861 ggtaggttcc ggcctggctg gcgcctccgc tgccgccacg cttgccgaac ttggctacaa
    10921 cgtcaaatgc ttctgctacc aggacagccc ccgccgcgcc cactccattg cggcccaggg
    10981 cggcattaac gcagccaaga actaccagaa cgacggcgac tccgtttacc gcctgtttta
    11041 cgacaccgtt aaaggcggcg acttccgcgc ccgtgaagcc aatgtctacc gtctggcgga
    11101 agtctcctcc aacatcattg accagtgtgt ggcccagggc gttcccttcg gccgtgaata
    11161 cggcggcctg ctggacaacc gctccttcgg cggcgcccag ctcaagcgaa ccttctacgc
    11221 acgcggacag acgggccagc agctcctgct gggtgcctac caggccctgg aaaaggaagt
    11281 ggccaaggga cacattgaaa tgttctcccg ccatgaaatg atggatctgg tgctggtgga
    11341 cggcgaagcc aagggcatcg tcacccgcaa tctggttacc ggcgaaatca aatcctacgc
    11401 aggggatacc gtcctgctct gcacgggcgg ctacggcaac gtgttcttcc tgtccaccaa
    11461 cgcgatgggc tgcaacgtca ctgccgccta caaggcctac aagcgcggtg ccttcttcgc
    11521 caacccctgc ttcacgcaaa tccaccccac ctgcattccg gtcaagggcg actaccagtc
    11581 caaactgacg ctgatgtcgg aatccctccg caacagtggc cgcatctggg tgcccaagtc
    11641 ccgtgaaacc gcagaaaaaa tccgtaaaaa ggaaatcaag ccttccgatg ttcccgaaga
    11701 agaacgggac tactacctgg aacgcaagta tccctccttc ggcaacctgg ctccgcgcga
    11761 catttcctcc cgcgccgcca aggaagcctg cgacgacggc cgcggcgtgg ccgtcaccgg
    11821 caagggcgtc ttcctggatt ttgcggatga aatcaagcgc atgggccgcg aatggattga
    11881 cggccaatac ggcaatctgt ttgacatgta cgaagaaatc acggacgacg acccccatga
    11941 aacgcccatg atgatctacc ccgcctccca ctacaccatg ggcggcctgt gggtggacta
    12001 caacctcatg tccaacgtga aggggctgca cgtcctcggt gaagccaact tctccgacca
    12061 cggcgccaac cgcctgggag cctccgccct gatgcagggc ctgtctgacg gctacttcgt
    12121 cattcccgcc acgctgcccg cttacctgac gaccaccaag cccggcgccg tcaccaccgc
    12181 cgccccggaa ttcaaggctg cggaagacga agtgaaggaa cgcatcaaca agctcctgaa
    12241 tgtgaagggc accaagacgg tggactcctt ccaccgggaa ctgggcctca tcatgtggga
    12301 agactgcggc atggcccgca cggaagaaag cctgacccac gccattgaac gcattcccca
    12361 gctccgcaag gaattctggg aaaacgtgcg cgtaaccggc acggcggacg gcatcaacgc
    12421 ggaactggaa aaagcctgcc gcgtggccga cttcctggaa ttcgcccagc tgctctgcta
    12481 tgacgccctg aaccgccagg aatcctgcgg cgcccacttc cgcgtggaat accagctgcc
    12541 ggacggcgaa gctaagcgca acgacgatga atacgcctat gtagccgcct gggaatacac
    12601 tggcgtggac agcctgcctg ttctccacaa ggaaccgctg accttcgaga acgtgcacct
    12661 tgccatccgc agctacaagt aaagatagcc aatacattaa cactcaaaag aaagattata
    12721 acatggctaa aacactcaat ctcactctca aggtctggcg ccaggaaaac cgggaagcca
    12781 agggccgcat tgagacctat gccgccaagg acattccggt ggacgcctcc ttcctggaaa
    12841 tgctggacat cgtcaatgaa ggcctggtca aggaaggcaa ggaacccatc cattttgacc
    12901 acgactgccg ggaaggcatc tgcggcatgt gctccctgac catcaacggc attccccacg
    12961 ggccggaacg ccaggtgacc acttgccagc ttcacatgcg caagttcaag gatggcgata
    13021 ccgtctggat tgaacccttc cgcgcgaagg ctttcccaat cctgcgggac ctgatggtgg
    13081 accgctccgc cctggaccgc atcatcgccg ctggaggcta tattgacgtg cgtaccggtt
    13141 ccgcgccgaa cgccaacaac atcgccgtgg aaaaagtgaa ggcggacgcc gcctttgacg
    13201 cggccgcctg catcggctgc ggcgcctgcg tggcctcctg taaaaacgct tccgccatgc
    13261 tgttcacctc cgccaagatc gcccatctca atctgctgcc gcagggccag ccggaacgtt
    13321 ccaagcgcgt cctggccatg atgaagcaga tggaagcgga aggctttggc aactgcacga
    13381 accagtatga atgtgaagcc gcctgcccga aaggcatcag cgtggacaac atcgcccgcc
    13441 tcaaccgcga cttcatgcgg gccaacgcca aggaaggcct ctgtttctaa agaagattcc
    13501 ttcttaagac gctctgtaaa aactcccggc ggcatcggct gtcgggagtt ttttcattac
    13561 cagatttcct tgaaccagga ataaaatacc agacagttgc ttcctcatcg tcgcgcagcg
    13621 taaaaaattg ttacaccgga aggcacccag taatccagga gaccgtactt ggaaatgccg
    13681 gacgaaacc
//
