LOCUS       c00017_gnlPro..        10379 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|LLJLILHE_17.
ACCESSION   c00017_gnlPro..
VERSION     c00017_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-05 16:46:13
            Original ID  :: gnl|Prokka|LLJLILHE_17
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 10379
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..10379
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[466:4994]"
                     /cutoff="10000"
                     /detection_rule="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /neighbourhood="10000"
                     /product="succinate2propionate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      467..4994
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /neighbourhood="10000"
                     /product="succinate2propionate"
                     /protocluster_number="1"
     cand_cluster    1..10379
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /kind="single"
                     /product="succinate2propionate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..10379
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="succinate2propionate"
                     /region_number="1"
                     /rules="(minimum(4, [AcetylCoA_hyd_C, AcetylCoA_hydro,
                     B12-binding, Biotin_lipoyl, Glyoxalase_4, HMGL-like,
                     MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma, PYC_OADA]) and
                     minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /tool="gutsmash"
     CDS             3..266
                     /locus_tag="ctg17_1"
                     /transl_table=11
                     /translation="KSTFRTPAYKRVDLGFSYQLAGGTDAIMDRGVFRHLKNIWIGVDV
                     FNLFDIKNVSSYYWITNIDNQQYAVPNYLTGRQLNARLIVDF"
     CDS             467..877
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: Glyoxalase_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg17_2"
                     /sec_met_domain="Glyoxalase_4 (E-value: 1e-27, bitscore:
                     86.3, seeds: 51, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEITHIEHLGIAVKSIEACLPYYEEILGMKCYNIEEVADQKVKTA
                     FFKVGQTKIELLEPTSEDSTIAKFIEKKGEGIHHIAFAVPDVQAALDEAESKGVKLIDK
                     APRGGAEGLNIAFLHPKSTCSVLTELCMPGKK"
     CDS             915..2468
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: CT_Btheta"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg17_3"
                     /sec_met_domain="CT_Btheta (E-value: 1e-292, bitscore:
                     960.5, seeds: 72, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSNQLEKVKELIALREQARLGGGEKRIESQHKKGKYTARERIAML
                     LDEGSFEEFDMFVQHRCTNFGIEKTKFLGDGIVTGYGTIDGRLVYIFAQDFTVFGGALS
                     ESLAMKICKVMDQAMKMGAPVIGLNDSGGARIQEGVNALAGYAEIFQRNILASGVVPQI
                     SGIFGPCAGGAVYSPALTDFNIMTRGTSYMFLTGPKVVKTVTGEDVTQEQLGGASVHTT
                     KSGVAHFAVDTEEEGLQLIRKLLSFLPQNNLEETPLIECKDPIDRLDDVLNDIIPDNAN
                     QSYDMYEVIGTIVDNNEFLEVHADYAKNIIVGFARFNGQSVGIVANQPKVMAGCLDSNA
                     SRKAGRFVRFCDAFNIPLVTLVDVPGFLPGTGQEYNGVILHGAKLLYAYGEATVPKITV
                     TLRKSYGGAYCVMSSKHLRGDMNYAWPTAEIAVMGPSGAVEVIFAKEVAASEDPAKATA
                     EKEAEYKKAFANPYNAAQYGYIDDVIEPRNTRFRIIRALQQLQTKKLSNPAKKHDNLPL
                     "
     CDS             2491..3375
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: OAD_gamma"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg17_4"
                     /sec_met_domain="OAD_gamma (E-value: 1.6e-12, bitscore:
                     37.7, seeds: 234, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTNKRFGVLLLFILLVSFGAQAQRATSMRINEVLVINEDNFVDDY
                     GKRHGWIELFNTSAGTVNIAGCFLTDDKNNPKKYPIPKGDVLTQIPPHQHTLFWADGEP
                     NRGTFHVNFTLDPSKENYIALYDADGKSLIDEITIPAAQKPDVSYGRIIDGKEEWAQLT
                     KVTPSTNNLTLDSNEKIENFKTNDSLGIGMTITAMAVVFLGLLLLFLIFKQVGKAAIAA
                     SKRNAQKAGAPVNVNTPDEVSGEVFAAIATALYEMSDDNHDIEHTVLTIRKVRRAYSPW
                     SSKIYSLRETPRK"
     CDS             3398..3829
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: Biotin_lipoyl"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1024:Biotin-requiring enzyme (Score: 63.9; E-value:
                     3e-20)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg17_5"
                     /sec_met_domain="Biotin_lipoyl (E-value: 5.8e-21, bitscore:
                     63.9, seeds: 40, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKSFKYTINGNVYKVHINSVVDDIAEVEVNGTPYNVKMEKPAKKQ
                     MVTLKRPAQAPTTASGEPVVTRPAASTTQGAVKTPLPGVILQIKCNVGDTVKRGQTLLI
                     LEAMKMENNINADRDGKIIEIKVHKGDSVLEGADLVVIG"
     CDS             3834..4994
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: OAD_beta"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg17_6"
                     /sec_met_domain="OAD_beta (E-value: 4.3e-154, bitscore:
                     502.3, seeds: 229, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQESFLSFLGDNLQLFLTYTGVYNATPGHIIMILVGLLFIFLAIK
                     YEFEPMLLIPIGFGILIGNIPFKDAGLQVGIYEQGSVLNILYQGVTSGWYPPLIFLGIG
                     AMTDFSALISNPKLMLIGAAAQFGIFGAYIIALQMGFEPNQAGAIGIIGGADGPTAIFL
                     SSKLAPNLMGAIAVSAYSYMALVPIIQPPFMRLLTTKKERLIRMKPPRAVSSTEKIIFP
                     IVGLLLTCFLVPSGLPLLGMLFFGNLLKESGVTRRLAETARGPLIDTITILLGITVGAS
                     TQATQFLTLNSIKIFGLGALSFVIATCAGVLFVKFFNLFLKQGNKINPLIGNAGVSAVP
                     DSARISQVVGLEYDPTNYLLMHAMGPNVAGVIGSAVAAGILLGFLG"
     CDS             5498..7240
                     /locus_tag="ctg17_7"
                     /transl_table=11
                     /translation="MSQVKGIPYGISDFKRLRNENFYYVDKTMYLPLIEKMPSYLFLIR
                     PRRFGKSLFLSLMRTYYDILQKDNFEKYFGDLWIGSHPTDQRNRFQVLYFDFSKAGCSQ
                     PGTDMMTSFNDYCGLIINQFAHEYASYYDADYKATIENIASAKAKLSYIEIKAKEKGYP
                     LYLIVDEYDNFTNVILSEHGQKMFHDLTHASGFYREYFKQFKGMFDRIFLMGVSPITLD
                     DLSSGYNIDWNISTDETFNAMMGFDETDVREMFHYYRQNDMLTGDIDTMIAEMKPWYNN
                     YCFARMALDSDRVFNCDMILYYLHNQVNFHRAPEEMVDKNICINYSKLKKLTGINHKSL
                     HEDSCMNTIKDIVAKGEVLVDLHTSFPAEKVMDIDNFRSLLYYYGLLTMCGTHGKLLKM
                     CIPNNCVREQYFGFLRDYYQQFHTINLSHLKDLIDDFAYDGQWKPFFESIALAYRENSS
                     VRDAMEGERNLQGFLKAYLALASYYLVEPELEMNYGYCDFFLLPDKKRYPDIGHSYILE
                     LKYAGRTTTDTELETQAEEGRRQLLQYSKDKIALQLAQDTTLHLILLQFRGWDLVKCEE
                     IASC"
     CDS             complement(7275..8054)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_M22"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg17_8"
                     /sec_met_domain="Peptidase_M22 (E-value: 3e-26, bitscore:
                     82.3, seeds: 111, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LRPINPVDEQRSSIEKYLSLVNRQLSTIMSCILNIETSTSVCSVA
                     LSADGEVLFEKSSFEGPSHAALLGVYVEEAIAVTKEKGLKLDAVAVSSGPGSYTGLRIG
                     VSVAKGLCFGYGIPLISIPTLEVLAVAALEQQNNASDCLYCAMLDARRMEVYAAIYDVN
                     LKTVRETSADIVDAETYASWLEKGKVCFFGNGAAKCREVITSPNALFIDNIHPLAVNMI
                     TLSEKAFAGSRFEDVAYFEPFYLKEFQATIAKNKVLG"
     CDS             8194..9054
                     /locus_tag="ctg17_9"
                     /transl_table=11
                     /translation="MTGFGKVTAELPSKKVTVEIKALNSKQLDLSTRIPSIYKDKEMQI
                     RSQLLQSLERGKVDFSIYIEYIGKDTPTQINLTAFESYYSQVKDIAEKLNIALPADWFQ
                     TLLKMPDVIKSEIVEVDESEWEVVFNAVKGAIKHLCDFRIQEGAMLQKLFEDKIGNIAR
                     LLTEVEEYEGERIEKIKARIMDNLEKVANQDYDKNRFEQEMIYYIEKLDVNEEKNRLDN
                     HLKYFISTMKDGHGQGKKLGFIAQEMGREINTLGSKSNHAEMQKIVVQMKDELEQIKEQ
                     VLNVL"
     CDS             9056..9625
                     /locus_tag="ctg17_10"
                     /transl_table=11
                     /translation="MAGKLIIFSAPSGSGKSTIINHLLKQNLNLHFSISATSRAPRGTE
                     QNGVEYYFLTPDEFRARIAAGDFLEYEEVYTDKYYGTLKSEVERQLNEGNNVIFDVDVV
                     GGCNIKKFYGDRALSVFIQPPSIAHLRERLEGRGTDAPEVIDSRIAKAEFELGFIPHFD
                     VCIVNDDLATAQAEAVEVIKDFLSKE"
     CDS             9622..9801
                     /locus_tag="ctg17_11"
                     /transl_table=11
                     /translation="MNNNRQLSRKWGYIFALTGIAALGTCIAGLIYKEYLIAFATGLVF
                     GVQAFNFIMWKKQR"
     CDS             9783..10379
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) CTP_transf_like"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg17_12"
                     /sec_met_domain="CTP_transf_like (E-value: 1.7e-24,
                     bitscore: 76.4, seeds: 65, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VEETTVKENNKLKTGIFSGSFNPVHIGHLALANWLCEFAGLDELW
                     FVITPHNPLKKRDDLMDDRLRLELVEAAVAGYAKFRTSDIEFTLPQPTYTIDTLRTLDR
                     TYPDREFHFIMGADNWSSINRWKESETLITSYPILIYPRKGYEINIPDNLPDIRKVDAP
                     LMEISSTFIRESLAAGKDIRFFLPEAIRNHKCFSNI"
ORIGIN
        1 tgaagagtac tttccgcacg ccggcctaca aacgtgtcga cctcggtttc tcttaccagc
       61 tggccggagg aaccgatgcg atcatggacc gcggagtctt tcgtcacctg aaaaatatct
      121 ggatcggagt ggacgtattt aacctgttcg atataaaaaa tgtcagttcc tattactgga
      181 tcaccaacat cgacaaccag caatatgctg taccgaatta cctgacaggc cgacaactca
      241 atgcacgact gattgtcgat ttctaaaaat atgccaataa gataatttgc caatatgccg
      301 ataaaaaaca ggatttgcca atgagaagtc aaggctttca ttggcaattt tgcatattgg
      361 caaattggca aattattatt aatgaaatat ttcttgattc ttcaaaaaga atgtaccttt
      421 gccatcaaaa caaaaagcat ttatcaatta ttaaattctt attgacatgg aaattacaca
      481 tattgaacat ctgggaattg cagtaaaaag catcgaagct tgtctgccgt attatgaaga
      541 aattttaggc atgaaatgct acaacatcga agaagttgct gaccaaaaag taaagactgc
      601 gttctttaaa gtaggccaaa caaaaatcga attacttgaa ccgaccagcg aagacagcac
      661 tatcgccaaa ttcatcgaaa agaaaggcga aggtattcac catatcgcat ttgctgtacc
      721 tgatgtacag gctgcattgg acgaagctga atcaaaaggt gtcaaactga tcgacaaagc
      781 tccccgcggt ggtgcagaag gtctgaacat tgcattcctt cacccgaaat caacttgcag
      841 cgtattgact gaactttgca tgccgggtaa aaaataatta atcagttcat ttctaacaac
      901 aaatcagaaa tacaatgagt aaccaacttg aaaaagtaaa agagcttatc gctcttcgcg
      961 aacaagcccg tttaggtggt ggagaaaaaa gaatcgaatc tcagcacaag aaaggcaagt
     1021 acacagcacg cgaacgtatc gccatgttgc ttgacgaagg tagtttcgag gagtttgata
     1081 tgttcgttca gcaccgttgt actaacttcg gtattgaaaa aacaaaattc ctgggtgatg
     1141 gtatcgtaac cggatatggt acgatcgacg gccgtttggt ctacatcttc gcacaggact
     1201 tcaccgtatt cggaggagct ttgtcagaat cactggccat gaagatttgt aaggtaatgg
     1261 atcaggccat gaagatgggt gcccctgtca tcggcttgaa cgactcaggt ggagcacgta
     1321 tccaggaagg cgttaacgct ctggcaggat atgctgaaat cttccagcgt aatatccttg
     1381 catccggtgt tgtacctcag atttcaggta tcttcggtcc gtgtgcaggt ggcgcagttt
     1441 attctccggc gctgactgac tttaacatca tgacacgtgg taccagctac atgttcctga
     1501 caggtccgaa agtagtaaaa accgttaccg gtgaagacgt aactcaggaa caactgggtg
     1561 gcgcaagcgt acacacaacc aaatcgggtg ttgcccattt cgctgtcgac acagaagaag
     1621 aaggtctgca actgatccgc aaattgctca gcttccttcc gcagaacaac ctggaagaaa
     1681 ctccgctgat cgaatgcaaa gacccgatcg accgtctgga cgatgtattg aacgacatca
     1741 ttcctgacaa cgctaaccag tcatatgaca tgtatgaagt aatcggcaca atcgttgaca
     1801 acaacgaatt cctggaagta catgctgatt atgctaaaaa tattattgtt ggtttcgcac
     1861 gtttcaacgg ccagtctgtt ggtatcgtag ctaaccagcc gaaagtaatg gcaggctgtc
     1921 tggacagcaa cgcttcccgt aaggcaggcc gcttcgttcg cttctgcgac gctttcaaca
     1981 ttcctttggt aacattggta gacgtaccgg gattccttcc gggaacaggc caggaataca
     2041 atggtgtaat ccttcacgga gccaaattgc tttacgctta cggcgaagca actgtgccta
     2101 aaatcactgt tacattgcgt aaatcttacg gtggtgctta ctgcgtgatg agttctaaac
     2161 acctgcgtgg cgatatgaac tacgcatggc cgacagcaga aatcgcagtt atgggcccga
     2221 gcggtgctgt agaagttatc ttcgcaaaag aagttgccgc atccgaagat cctgcaaaag
     2281 caacagccga aaaagaagca gaatacaaga aagcattcgc aaacccgtac aacgcagctc
     2341 aatacggtta tatcgacgat gtgatcgaac cgcgtaatac ccgtttccgt atcattcgtg
     2401 ctttacaaca attgcagacg aaaaagttaa gcaatcctgc taagaaacat gacaatctgc
     2461 ctctataatt cttaaaacag gaaaatgaat atgactaaca aaagatttgg agtattgctg
     2521 ctgttcatcc tgctcgtatc attcggggca caggcacagc gtgcaacctc catgcgaata
     2581 aatgaagtgc tggtcatcaa cgaagataat ttcgttgacg actatggcaa acgtcacggc
     2641 tggatagaat tattcaatac ttctgccgga acggttaata ttgcaggttg tttcttgaca
     2701 gacgacaaga acaatcctaa aaaatatccg atccccaagg gtgacgtact aactcagatc
     2761 cccccccatc aacacactct gttctgggcg gatggtgaac ctaaccgtgg tacttttcat
     2821 gtcaatttca cgttagaccc gtcaaaagaa aattatatag cactttatga cgccgatggt
     2881 aaatccttga tcgacgaaat aacaattccg gctgcacaaa aaccggatgt tagctatggt
     2941 agaattattg acggaaaaga agaatgggca caactcacaa aagtgactcc cagcacaaac
     3001 aacctgacgt tagattctaa cgaaaagatc gaaaacttta agacaaatga ctctttgggt
     3061 atcggtatga ctattacagc tatggctgtt gtttttctag gcttgctcct tcttttcctg
     3121 atcttcaaac aagtcggaaa agcagctatc gcagccagca aacgtaatgc tcagaaagca
     3181 ggggcacctg ttaatgtaaa tacaccggac gaagtttcgg gcgaagtttt tgcagcaatc
     3241 gctacagctt tgtatgaaat gagtgatgac aatcacgaca tcgaacatac agtgcttaca
     3301 atccgcaaag ttcgccgtgc atattctcca tggagttcta agatctatag tttacgtgaa
     3361 actcccagaa agtgattatc tctaaaaaca aacaagaatg aaaagtttta aatataccat
     3421 caacggtaac gtatataaag tacacatcaa ttcagtggtc gacgatatcg ctgaagtaga
     3481 agtaaacggt actccttata atgtaaaaat ggagaaaccg gcgaaaaaac aaatggttac
     3541 actcaaacgc ccggcacagg ctcctactac agccagcggc gaaccggttg ttactcgtcc
     3601 ggcagcatct acaacccagg gcgccgttaa aactccgctt ccaggtgtta tcctgcaaat
     3661 caaatgcaat gtaggcgaca ctgtgaagag aggacaaact ttacttatcc tcgaggctat
     3721 gaagatggaa aacaacatca acgctgaccg cgacggtaag attattgaaa ttaaagtaca
     3781 taagggagac tccgtactgg aaggtgctga tctcgtcgta atcggataag agtatgcaag
     3841 agagtttttt atcattcctg ggtgacaacc tacagttgtt cctcacctat acaggagtat
     3901 ataatgcaac tccgggccat atcattatga tattggttgg tttgctcttt atattccttg
     3961 cgattaaata tgaatttgaa cccatgttgc tgatccctat cggattcggt atcctgatcg
     4021 gtaacattcc ttttaaagat gcagggcttc aggtaggtat ctacgaacaa gggtctgtac
     4081 ttaacatcct ctatcaaggg gtaacctccg gatggtatcc gccgttgatc ttcctcggta
     4141 tcggggcgat gaccgacttc tccgctttga tttccaatcc aaagctgatg ttgatcggtg
     4201 ctgccgccca gttcggtatc ttcggtgctt atattatcgc tcttcagatg ggattcgaac
     4261 cgaaccaggc cggtgctatc ggtattatcg gtggtgctga cggtcctacg gctatcttcc
     4321 tgtcttccaa gctggcccct aacctgatgg gtgctattgc ggtgtcagcc tactcatata
     4381 tggcgttggt acctattatc cagccgccgt tcatgagact gcttacaaca aagaaagaac
     4441 gtctgatccg tatgaaaccg ccgagagccg tttcttctac agaaaagatc atcttcccga
     4501 tcgtaggtct gttgctgact tgcttccttg taccttcagg tctgcccttg ctgggtatgt
     4561 tgttcttcgg aaacctgttg aaagaaagtg gtgtaacccg tcgtctggct gaaacagccc
     4621 gcggtccgct gatcgataca atcaccatcc tgttaggtat cacagtaggt gcttctacac
     4681 aggcaactca gttcctgaca ctgaactcta tcaagatctt cggtttaggt gcgttgtcat
     4741 tcgtgattgc aacctgtgcc ggtgtattgt tcgttaagtt cttcaacctg ttcctgaaac
     4801 aaggcaacaa gatcaatccg cttatcggta atgccggtgt atctgccgtt cccgactcag
     4861 cacgtatctc tcaggttgta ggtctggaat atgacccgac caactatctg ttgatgcacg
     4921 ccatgggtcc gaacgtagca ggtgtaatcg gttctgctgt agcagccggt atcctgttag
     4981 gattcttagg ataataaaac aagtgacagt tgatagatgg caagtgacag ataaatagaa
     5041 tcttttctaa atctgtcaac tgtcacttat caactgtcaa ctttttatac attttgttcg
     5101 acctccatcg gatttgtttc cggattagtt acttcttcca atgtcgtccc cacaaacaac
     5161 cataccatca aaaggacaat cgcaataata accccgatga tcaaccatag atttttcttt
     5221 ttcatacctt cgtaattctg attttgtttt atatgagcat aaaacaacag aaacaagtct
     5281 ttggtttaaa aagatctatg agtaaaatac gaaacctact gccatactat catagttgac
     5341 aaatattcat ccgattacaa atgatttagc accatactct catacgcaat tcatataata
     5401 atagactgta aaacacaaag ctggaatact ttctcaaaca ttgttttatt tgccggaata
     5461 aactaacttt gtctctatat cttaaaaagt atccaacatg agccaagtaa aaggaatacc
     5521 atacggaata tctgatttca aacggttgag aaacgaaaac ttttattacg tagacaagac
     5581 gatgtatctg ccgctgatcg aaaagatgcc cagctacttg tttcttatcc gtcccagacg
     5641 attcggaaaa agtctgttcc ttagcttgat gcgtacctat tatgatatat tgcaaaagga
     5701 taatttcgaa aagtatttcg gcgatttatg gattggcagc cacccgaccg accagcgcaa
     5761 ccgctttcag gtgctttact tcgatttctc aaaagccggt tgttcgcaac cgggaaccga
     5821 tatgatgacc agcttcaacg actattgcgg tctgatcatc aatcagttcg cacatgaata
     5881 tgcatcctat tacgatgccg attataaagc tacgatcgaa aatatagcaa gtgccaaagc
     5941 aaaactgtcg tacatcgaga taaaagcaaa agaaaaaggg tatccgcttt atcttatcgt
     6001 agacgaatat gacaacttca caaacgtcat actgagtgaa cacggacaga aaatgtttca
     6061 cgacctaaca catgccagcg gtttctacag ggaatacttt aaacagttca aagggatgtt
     6121 cgaccggatt ttcctgatgg gggtcagtcc tatcactttg gatgatttat cgagcggtta
     6181 taacatcgac tggaatatct cgactgacga aacttttaac gcaatgatgg gattcgatga
     6241 aacagatgtt cgtgaaatgt ttcattatta ccggcaaaac gatatgctga caggagacat
     6301 agatacaatg atcgcagaaa tgaaaccgtg gtataataat tattgtttcg cacgaatggc
     6361 attggatagt gaccgggtgt tcaattgtga catgattttg tattatttac acaatcaggt
     6421 aaatttccac cgtgccccgg aagagatggt agacaaaaat atttgcataa attacagcaa
     6481 actaaaaaag ctaaccggta tcaaccataa aagtttacac gaagatagct gtatgaatac
     6541 tatcaaagat attgtcgcaa aaggagaagt gctagtcgac ttgcacacct ctttcccggc
     6601 tgaaaaagta atggatatcg ataatttccg aagtctactt tattactacg gactgcttac
     6661 tatgtgcggt acacacggaa aactattaaa aatgtgtatc cccaataatt gcgtacgtga
     6721 acaatacttt ggtttcctgc gcgattatta tcaacagttt catacaataa acctttctca
     6781 tctgaaagat ttaatagacg acttcgctta cgacggccaa tggaaaccgt ttttcgaatc
     6841 catcgccctt gcctatcgtg aaaactcttc cgtacgtgat gctatggaag gagaaagaaa
     6901 tctgcaaggt tttctgaagg catatctggc actcgcttct tattatctgg tagaaccgga
     6961 actggaaatg aattacggtt actgcgattt ctttttatta cctgacaaaa agcggtatcc
     7021 cgatatcgga cacagctaca tattggagtt aaagtacgct ggacgtacca ccaccgacac
     7081 ggaactcgaa acgcaagcag aagaaggacg ccgccaacta ttacaataca gtaaagacaa
     7141 aatcgcttta cagttggccc aagacacaac acttcatttg atactgcttc aattccgggg
     7201 ttgggatttg gttaagtgtg aagaaatagc ttcctgctaa caatcttcac cggatgatag
     7261 ctttcaaaac gctatcatcc caacacctta ttcttagcga ttgttgcctg aaattctttc
     7321 aggtagaacg gctcgaaata agcgacatcc tcaaaccgac ttccggcaaa tgctttttca
     7381 gacaaggtta tcatattaac agccagcggg tggatattat caataaagag cgcattcgga
     7441 gaagtaatca cctcccgaca tttggctgca ccgttcccaa agaaacaaac tttccctttt
     7501 tccagccagg aagcataagt ttctgcatct acaatatcag cagacgtttc gcgaaccgtc
     7561 ttcaaattaa catcatagat agctgcatac acctccatcc gacgggcatc gagcatggcg
     7621 caatacaaac agtcggacgc attattttgc tgttccaatg cggcaacagc caacacttcc
     7681 agcgtaggga tactgatcag aggtatgccg taaccgaaac acaaaccttt ggcgaccgat
     7741 acgccgatac gcaatccggt ataagatccc ggaccgctgc tgacagctac tgcatccagc
     7801 ttcaatcctt tttctttggt caccgcaata gcctcttcca cataaacacc caacaaagca
     7861 gcatgcgacg gaccttcaaa cgaactcttt tcaaaaagca cctcaccatc agccgataaa
     7921 gcgacggaac acaccgaggt cgatgtttca atatttaaaa tacaagacat aatagttgac
     7981 agttgacggt tgacaagtga cagatatttt tcaatagaac tccgctgttc atcaaccgga
     8041 ttaattggtc gcaaaagtac aaaaacgtct ttatacgaat gagaaaataa cgaacttttt
     8101 ctctatcagg acgaagaatt atcaactgtc aactgtcaac tatcaactga ataagctatc
     8161 tttgcacaaa tttttagaac aatgatacaa tcaatgactg gattcggtaa ggttacagcc
     8221 gaacttcctt caaaaaaggt aaccgtagaa ataaaagcac tcaacagcaa acaactggat
     8281 ttatcaaccc gcatcccttc tatctacaaa gataaggaaa tgcaaatccg tagccagctg
     8341 cttcagtcgc ttgaacgggg taaggtcgat ttcagcattt atatcgaata tataggaaaa
     8401 gatactccta cccagatcaa ccttaccgct tttgaaagtt attacagcca ggttaaggat
     8461 attgcagaaa aactgaatat tgcacttccg gctgactggt tccagacatt actaaaaatg
     8521 ccggacgtta tcaaatctga aattgtagaa gtagacgaaa gcgaatggga agttgttttc
     8581 aatgcggtaa agggagccat caaacatctt tgtgacttcc gcatccagga aggcgccatg
     8641 ctgcaaaagt tatttgaaga caaaatcggt aatatcgccc gcctgctgac cgaagtggaa
     8701 gaatatgaag gcgaacgcat cgaaaagatc aaagcccgta tcatggataa cctcgaaaag
     8761 gtagccaacc aggattacga caagaaccgc ttcgagcagg aaatgatcta ttacatcgaa
     8821 aaactggatg tgaacgaaga aaagaaccgc ctcgacaacc atctgaaata tttcatcagc
     8881 acgatgaaag acggacacgg acaaggcaaa aagctcggtt tcatcgctca ggaaatgggc
     8941 cgcgaaatca acacgctcgg ttcgaaaagc aaccatgcgg aaatgcagaa aattgtcgtt
     9001 cagatgaaag acgaactgga acaaatcaag gaacaggtac taaacgtatt ataatatggc
     9061 tggtaaatta attatattct ccgccccgtc aggctcaggt aaatcaacca tcatcaacca
     9121 tctgctaaaa cagaacctga acctgcattt ctctatctcg gcaacaagcc gtgcaccgcg
     9181 cggaacagaa cagaacggtg tggaatatta tttcctgact cccgacgaat tccgggcccg
     9241 tatcgctgcc ggtgattttc tggaatatga ggaagtatat accgataaat actacggcac
     9301 attgaaaagt gaagtggaac gccaactgaa cgaaggcaac aacgttatat tcgatgtgga
     9361 cgttgtcggc ggatgcaaca tcaaaaagtt ttatggtgac cgtgctcttt cagtatttat
     9421 ccagccgccc agcatcgccc atctgcgtga acgtctggaa ggtcgtggta cggatgctcc
     9481 cgaagtgatc gacagccgta tcgcaaaagc ggaattcgaa ctgggattta ttcctcattt
     9541 cgatgtctgc atcgtaaacg acgaccttgc gacagcacag gccgaagcag tggaagttat
     9601 aaaagatttt ctgtctaaag aatgaataac aacagacaat tatcacgtaa atggggatat
     9661 attttcgcac tgaccggaat cgcggcattg ggaacctgca ttgcaggcct catttataaa
     9721 gaatatctca ttgcatttgc aaccggactc gtattcggcg tacaggcatt caactttata
     9781 atgtggaaga aacaacggta aaggaaaaca acaaactgaa aaccggaatc ttttccggtt
     9841 ctttcaaccc ggttcacatc ggtcatttgg ccctggccaa ctggctgtgt gagtttgcgg
     9901 ggttggacga actgtggttt gttatcacgc ctcataaccc gctaaagaaa cgcgacgacc
     9961 tgatggatga ccggctccgg ctcgaactgg tcgaagctgc cgttgccgga tatgctaaat
    10021 tccgtaccag cgatatcgag tttacgcttc cccaaccgac ttacacgata gacaccttac
    10081 gtaccctcga ccgtacatat cccgaccgcg aatttcattt tataatggga gccgacaact
    10141 ggtcgtcaat caatcgctgg aaagaatcgg aaacgttaat taccagctac cctatcctga
    10201 tttatccgcg taaaggatac gaaatcaaca tccccgacaa ccttcccgac atccgtaaag
    10261 tcgatgctcc gctgatggaa atatcctcca cttttatacg cgaatcactg gcagccggca
    10321 aagatatacg tttcttctta ccggaagcaa tacgtaacca taagtgcttt tctaatata
//
