LOCUS       c00018_gnlPro..        13655 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|OBCJJJFM_18.
ACCESSION   c00018_gnlPro..
VERSION     c00018_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-05 16:28:56
            Original ID  :: gnl|Prokka|OBCJJJFM_18
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 13655
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..13655
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[635:3655]"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      636..3655
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
     cand_cluster    1..13655
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /kind="single"
                     /product="Pyruvate2acetate-formate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..13655
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Pyruvate2acetate-formate"
                     /region_number="1"
                     /rules="((PFL_acetate1 or PFL_acetate2) and Radical_SAM)"
                     /tool="gutsmash"
     CDS             636..2858
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: PFL_acetate1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Gly_radical"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg18_1"
                     /sec_met_domain="Gly_radical (E-value: 4.6e-47, bitscore:
                     151.2, seeds: 99, tool: rule-based-clusters)"
                     /sec_met_domain="PFL_acetate1 (E-value: 0.0, bitscore:
                     1171.0, seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNKVFKDGLWSKEINVSDFVHTNITPYEGDASFLAGPTERTKKVW
                     NECLKALEEERANNGVRSLDNVTVSTITSHKAGYIDRENELIVGLQTDELLRRAIKPYG
                     GIKVVEKACHENGVEVDEKVKDIFTHYRKTHNDGVFDAYTEEIRSFRSLGFLTGLPDNY
                     ARGRIIGDYRRLALYGIDRLIEAKQEDLHNITSPMTDARIRLREEVAEQIKALKEIKIL
                     GEYYGLDLGRPATNAQEAVQWVYMAYLAAVKEQDGAAMSLGNVSSFLDIYIQYDLDHGK
                     IDESFAQELVDQFIIKLRMVRHLRMQSYNDIFAGDPTWVTESIGGRFNDGRTKVTKTSF
                     RFLQTLYNLGPSPEPNMTVLWSPELPEGFKEFCAQVSIDTSSIQYENDTLMREVRNCDD
                     YGIACCVSYQAIGKQIQFFGARCNLAKALLLAINGGRCENTGTVMVKDIPVLTGDLLNF
                     EEVWSNYKKVLMQIARVYNDAMNIIHYMHDKYYYEKAQMAFIDTDPRINLAYGVAGLSI
                     AIDSLSAIKYGKVRAKRNDIGLTEGFDIENAYPCFGNDDDRVDHLGVDLVYFFSEELKK
                     HPVYKNARPTLSLLTITSNVMYGKKTGATPDGRAKGVAFAPGANPMHGRDKNGAIASLS
                     SVAKLRYRDAQDGISNTFSIVPKSLGVDQETRIENLVTMMDGYFTKGAHHLNVNVLNRE
                     MLEDAMEHPEKYPQLTIRVSGYAVNFIKLSREHQLEVISRSFHERM"
     CDS             2927..3655
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: Radical_SAM"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1015:4Fe-4S single cluster domain (Score: 77.8;
                     E-value: 3.2e-24)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg18_2"
                     /sec_met_domain="Radical_SAM (E-value: 1.3e-27, bitscore:
                     89.4, seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIRVHSYESMGTFDGPGLRLVVFLQGCNFRCLYCANPDTIDTKGE
                     STETTIDEIVRMAVSQKAFFGKKGGVTFSGGEPTLQAKALIPLFQRLKEQSIHICIDTN
                     GSIWNEEVKELLQWTDLVLLDIKEFNNVRHRQLTERSNEQTIRTAGWLEKNGKPFWLRY
                     VLVPGYSSFEEDIRALGEHFKNYQMIQRVEILPYHTLGVHKYEAMGKEYKLNGIKENTL
                     KQLETAKTLFGEYFNTVYLN"
     CDS             3757..4506
                     /locus_tag="ctg18_3"
                     /transl_table=11
                     /translation="MKRLLLLCLTYIMCVGNHQMAAQDSSESPGIFNSLAVGVSASTTG
                     IGIDVASPIGSYLAVRAGVSFMPNFTYSTDVDVDIEGSYEGNIPTSIDVEGGMGRTAGE
                     ILLNVYPFKSSSFFVCGGAYFGGGKLIKIKGHSDELAELIKEGQEVGIEIGNYRIPVDQ
                     NGNISGGLKVSSFRPYLGLGFGRAIPKKRIGFMFEMGVQFHNTPKVYTNNGDLSDLTAE
                     ADNDFTDIIDKLTVYPVLKFRLCGKIF"
     CDS             complement(4585..5172)
                     /locus_tag="ctg18_4"
                     /transl_table=11
                     /translation="MSSREDILQSIRRATHVKYEKPDLKPLEDMALTYPSKVEQFYLIM
                     KQVGGEAILLEKEEDVNDFIKKAYPGAKRIASNLKTITCATFNPDDVEDPAELNGTDLA
                     VIDGKIGVAENGAVWIEQDVKQRAIYFIAEKLVILLNKNKIVNNMHEAYKLIDTGEYGF
                     GTFISGPSKTADIEQALVMGAHGARDVMVVLI"
     CDS             complement(5175..6542)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_8"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg18_5"
                     /sec_met_domain="Fer4_8 (E-value: 1e-11, bitscore: 37.4,
                     seeds: 153, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 2.7e-05, bitscore: 16.8,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSTKHSKAAAEFLKNKKQAAWHDETLWLVRAKRDRLSKEVPEWEE
                     LRNMACATKLYSNSHLDELLVEFENNARANGAHVYWAKDADEYCNIVYNILNQHGVKHF
                     IKSKSMLAEECELNPFLENKGIEVVESDLGERILQLMHLKPSHIVLPAIHIKREQVGEL
                     FEREMGTEKGNFDPTYLTHAARKNLRQKFIHAEAAMTGANFAVASTGEIVVCTNEGNAD
                     MGTSQPKLQIAAFGMEKIVPDRESLGVFTRLLARSATGQPITTYTSHYRKPREGGELHI
                     IIVDNGRSKILADQKHIKTLNCIRCGACMNTCPVYRRSGGYSYTYFIPGPIGINLGMLK
                     APLHYYDNVSACSLCYSCSFVCPAKVDLAEQIYLWRQDLDKLGKADRMKRVMSGGMEFM
                     MNRPLIFNMALKWAPLVNGMPRFLIYNGLNDWGKGREMPKFAKESFNEMWKKGKVK"
     CDS             complement(6539..7285)
                     /locus_tag="ctg18_6"
                     /transl_table=11
                     /translation="MTMKVGLFIPCYINAVYPQVGIASYKLLKSLGVDVDYPLNQTCCG
                     QPMANAGFENKAVDLARHFDEQFKNYDYIVGPSASCVVFVRDNYSRLLKEDKHRCASEG
                     KIYDICEFIHDIVRPSSLKAKFPHKVSLQNSCHGVRLMKLSSASELNIPYFSKLRDLLS
                     LVEGVEVVEPERKDECCGFGGMFAVEEDAVSVQMGHDKVMRHIATGAEYIVGADSSCLM
                     HQNGIIARDKLPIKTLHIVEILAAGL"
     CDS             complement(7591..8202)
                     /locus_tag="ctg18_7"
                     /transl_table=11
                     /translation="MKRTEPVHVAVAETSVIVRSGLVAVLKRMPDLTIQPVEITSLEGL
                     QNCMQGHQPDILIINPTFGGWFNVDEFKSNYPQASTKCVSLLCSVTDTNLLKGYDESIA
                     LYDDIEVLNKKLVDLMNLGVDETDGEQETLSQREKEIICCVVRGMTNKETAEKLFLSIH
                     TVITHRRNIARKLQIHSPAGLTIYAIVNKLVELSEVKMNL"
     CDS             complement(8199..8894)
                     /locus_tag="ctg18_8"
                     /transl_table=11
                     /translation="MYKTSKYTPTDKMSYLICDNYTLLQVMSRFDLSLGFGDKTVQEVC
                     RENGVDCRTFLAVVNFMIEDSDRMEDDVKDISMPSLMNYLKQAHHYFLDFCLPTIRRKL
                     IEAIDCSTENEVAFLILKFFDQYAGEVRKHMDYEDMNVFTYVENLMAGRETGGFRISQF
                     ARRHDQIDATLTELKNIIIKYYPAKGNNHLLNAVLFDIFSCEQDLASHCRVEDYLFVPA
                     VLRLEKEGK"
     CDS             complement(9021..9485)
                     /locus_tag="ctg18_9"
                     /transl_table=11
                     /translation="MKKIIPILIAILICFGVGCTASYFQSEAILNWYPTLDKPSLTPPD
                     MAFPIAWSLIYLCMGISIGLIWHMWTIRRQMIIRLFGFQLLFNFTWSIFFFYLRSPLLG
                     FANILVLDVLVVYYMIESYPVKKSSAYLFVPYLLWLILATYLNGYILMYN"
     CDS             complement(9770..10495)
                     /locus_tag="ctg18_10"
                     /transl_table=11
                     /translation="MILNCAIVDDEPLALELLRSYVEKTSFLRLVGRYSSAVQAMTEIP
                     LREEVHVLFLDIQMPELNGLEFSRMVSPETRIIFTTAFGQYALDSYKVNALDYLLKPIS
                     YVDFLQSVNKAVQWYELKQKADNGVDADEADDCIYVKSDYKLLRIALDRILYIEGLKDY
                     IKIHVEDEPKAILSLVSMKAMEEKLPSSRFIRVHRSFIVQKSKIKVVDRGRIVFGKEYI
                     PISDSYKQELQMYLNSHSV"
     CDS             complement(10492..11547)
                     /locus_tag="ctg18_11"
                     /transl_table=11
                     /translation="MKQLFSQRRFLELSIHIVSWLLIFGFPLVFMDRGSGFNLAQFLRH
                     SCVPLCYFVIFYVNYLWLVPRYMFTDEMRKYILSNAVLILCLSVLLHVFLESISTPPPP
                     EFARHIPPRWIFYARDMGMMIFVAGLGAAIRTSLRWRQAEERLIEAERQKTEAELKNLK
                     NQLNPHFLLNTLNNIYALIAFNSDKAQEAVQELSKLLRHVLYDNQQTFVPLEKELDFIR
                     NYVALMRIRLPQQVEVSVNLEVDSGGALQIAPLIFISLIENAFKHGISPTVDSFISISI
                     FGHTDGTVRCEILNSNHPKSGQDKSGSGVGLEQVSKRLELIYPGHYEWIKGISENGQVY
                     SSILTIQTKSL"
     CDS             complement(11769..12989)
                     /locus_tag="ctg18_12"
                     /transl_table=11
                     /translation="MNGTNLFKIALRALANNKLRAFLTMLGIIIGVASVIAMLAIGQGS
                     KKSIQQQISEMGSNMIMIHPGAEMRGGVRQDPSAMQTLKLENYEKLSEECTYLSGISPN
                     VSSSGQLVAGANNYPSSVSGVSMDYLTIRQLTVEQGEMFTENDIRTSAKVCVIGKTIVD
                     NLFPDGSDPIGKVIRCNQIPFRVIGVLKSKGYNSMGMDQDDVVLAPYSTVMKRLLAQTY
                     LSGIFASALTEEMTEEAVDEITTILRREHKLKETDADDFTIRTQQELSSMLNTTTDLMT
                     TLLACIAGISLVVGGIGIMNIMYVSVTERTREIGLRMSVGARGVDILSQFLIEAILISI
                     TGGLIGVIIGCGASFMIKAIAHWPVFIQPWSVLLSFLVCTVTGVFFGWYPAKKAADLDP
                     IDALRYE"
ORIGIN
        1 aaggaagttt gggtgagtgg ctgaaaccac cagtttgcta aactgacgta cgggtaaccg
       61 taccgggggt tcgaatcccc cagcttccgc gaataagtcg taaattaatt ttacgactta
      121 ttttttatat tcatttttca acagtttgct gtcaaggctt tcgggaggaa gagtaaaggt
      181 gctttttaga ctttcaattt tactacataa aacatatgat acttcttcat agaaattaaa
      241 ttccgattta taatagtaat agcataaaaa aaatcatttt ttattttgca gattaaaaac
      301 aaacttctaa ctttgcaccg tcttagaaaa agaattaaga ctaactgatg gcggtatcgt
      361 ctagtggcct aggacgcagc cctctcacgg ctgaaactcg ggttcgattc ccggttccgc
      421 tacttttaga agctaattgg tttattgtca ccaattagct ttatttttta tggaattgtt
      481 ataaagagtc cttattgttt tttcatttat tgaccacttt atacttaaaa atgcacaagt
      541 attcgcatta tacctactaa tagtgatgca tagctcacaa aaaaggagta cctttgcagc
      601 cctaaatctc ttaataatgg aataacagta tggaaatgaa caaagttttt aaggatggat
      661 tgtggagtaa ggaaattaat gtttcagact tcgtacatac caacattacc ccttatgagg
      721 gcgatgcctc atttctggca ggccccacag agcgaactaa aaaagtgtgg aacgaatgcc
      781 tcaaggcact agaagaagaa cgtgccaata acggagttcg ttcccttgat aatgtaacag
      841 tatctaccat cacctcacat aaagcaggat acattgaccg tgaaaacgaa ctgattgtag
      901 gtcttcaaac ggatgaactt ttgcgccgtg ccatcaaacc ttatggtggt atcaaagtcg
      961 tagaaaaagc ctgccatgaa aacggtgtgg aagtagatga aaaagtaaag gatatcttta
     1021 ctcattatcg caaaacccat aatgatggcg tatttgatgc ttacaccgaa gaaatccgct
     1081 ctttccgttc actcggtttc ctgaccggtc tgcccgataa ttatgcacgc gggcgtatca
     1141 tcggtgacta ccgccgtttg gcactgtatg gtatcgaccg actgattgaa gcaaaacaag
     1201 aagatttgca caatatcacc agtccgatga ccgatgcccg tatccgcctg cgcgaagaag
     1261 tagccgaaca aatcaaagca ctgaaagaaa taaagatatt gggtgaatat tacggactcg
     1321 acttgggtcg tcccgctact aatgcacaag aagctgttca gtgggtttat atggcatatc
     1381 ttgctgccgt gaaagaacaa gatggagcag ctatgtcatt gggcaacgtt tcttcattcc
     1441 tggatatcta tattcaatat gatttggatc atggtaaaat tgacgagtca tttgcgcagg
     1501 aactggtaga ccagttcatt atcaagttgc gtatggtccg tcatctgcgt atgcaatcat
     1561 acaacgatat ctttgcaggt gatcccacct gggtaaccga gtctatcggc ggacgcttca
     1621 acgacggacg taccaaggtt acaaaaactt ccttccgttt cttgcagaca ctatacaatc
     1681 tgggtccgtc acccgaacct aatatgactg tactgtggag tccggaattg ccggaaggtt
     1741 tcaaagaatt ctgtgcacaa gtttctatcg acacttcttc tatacaatac gaaaacgaca
     1801 cgctgatgcg cgaagtgcgt aactgtgatg attatggtat cgcctgctgc gtttcttatc
     1861 aggctatcgg caaacaaatc cagttcttcg gagcacgttg caatctggct aaagccctat
     1921 tgctggctat caatggcgga cgttgtgaga atacaggaac tgtaatggtg aaagatattc
     1981 ctgtattgac aggggacttg ctgaactttg aagaagtatg gtctaattat aagaaagtat
     2041 taatgcaaat tgcacgtgtg tataatgatg cgatgaatat cattcactat atgcacgata
     2101 aatattatta tgaaaaggct caaatggcat tcattgatac cgatccacgt atcaatctgg
     2161 catatggcgt agccggtctg tccattgcca ttgactcatt gtctgccatc aaatacggca
     2221 aagtacgtgc caaacgtaat gatataggtt tgaccgaagg ctttgatatt gaaaatgcat
     2281 atccttgctt cggtaatgat gatgaccgcg tagaccactt aggggtagat ttggtttatt
     2341 tcttcagtga agaattaaag aaacatccgg tatacaaaaa tgcccgccct accctgtcac
     2401 tgctgactat cacctccaat gtaatgtacg gcaagaaaac aggtgccact cctgatggtc
     2461 gtgccaaagg agtggctttc gctccgggtg ccaacccgat gcacggacgt gacaagaacg
     2521 gtgccatcgc ctcattgagt tctgtagcca aactacgcta tcgtgatgcc caggacggca
     2581 tcagtaacac gttctctatc gtaccaaaat cactaggggt agaccaggaa acccgtatag
     2641 agaacctggt aaccatgatg gacggttatt tcaccaaagg agcacatcat ctgaatgtaa
     2701 atgtgctgaa ccgtgaaatg ttggaagatg caatggaaca tcctgaaaaa tacccgcaac
     2761 taaccatccg cgtatcaggt tatgccgtaa acttcatcaa attgagccgt gaacatcagc
     2821 tggaagtaat cagccgttct ttccacgaaa gaatgtaaca tcacatatac attcatcgta
     2881 ggggcgggtt ttaaacctgc ccttaccagt ttaaagacaa accattatga tcagagtcca
     2941 ttcttacgag tcaatgggga cgtttgacgg tcccggttta cgcttagtcg tatttttaca
     3001 aggatgcaat ttccgatgcc tctattgtgc caaccccgac acaattgaca ccaaaggtga
     3061 aagtacggaa acaacaatag acgaaattgt gcgtatggcc gtcagccaaa aagctttttt
     3121 cggtaaaaaa ggaggtgtga ctttcagcgg cggcgagcct acattgcaag caaaagcact
     3181 gattccgtta ttccagcgat taaaagaaca aagcatccac atctgtatag ataccaacgg
     3241 cagtatatgg aatgaagaag taaaggaact gctacaatgg acagacctcg tattattaga
     3301 catcaaggaa tttaataatg tgcgccatcg gcaactgaca gaacgcagca acgaacaaac
     3361 catacgtacc gccggatggc ttgaaaaaaa cggaaagcct ttttggttgc gctatgtatt
     3421 agttccaggc tatagttcct ttgaggaaga tatacgggca ttaggagagc acttcaagaa
     3481 ttatcaaatg attcaaagag tagaaatact accttatcat acattaggcg tacacaaata
     3541 tgaagccatg ggaaaagaat acaaactaaa cggaataaaa gaaaatactc taaaacaatt
     3601 ggaaacagcc aaaacgttat ttggtgaata tttcaatacc gtatatttaa attaaaaata
     3661 tactgaagac aagatgttgc tataaatcaa tggaaatatt tcatcatttc aataaaatta
     3721 tctaatttcg catctaaaac ataaattatt ataaatatga aaagactact attactctgc
     3781 ctaacttaca ttatgtgtgt aggcaaccat cagatggctg ctcaagactc ttctgaaagt
     3841 cctggtattt ttaattcatt agctgtaggc gtcagtgcaa gtaccacagg tataggtatt
     3901 gatgtagcca gtcctatagg aagttacttg gctgtacgtg caggagtttc ttttatgccg
     3961 aactttactt attctacaga tgtggatgta gatattgaag gttcttatga aggaaatata
     4021 cctaccagca tagatgtaga aggaggaatg ggacgtactg ccggtgaaat attgctgaat
     4081 gtatatcctt tcaaatcatc cagttttttt gtatgcggtg gtgcttattt cggaggagga
     4141 aaactcatca agattaaagg gcacagcgat gagttggcag aactgattaa agaaggacaa
     4201 gaagtaggta ttgaaatcgg aaactatcgt atacctgtag atcagaacgg aaatatatct
     4261 ggtggtttga aggtttcttc attccgtcct tatcttggac taggtttcgg aagagcgatt
     4321 cctaagaaac gaattggctt catgttcgaa atgggtgtgc aattccataa cactcccaaa
     4381 gtatatacca ataacggaga tttgtctgat ttaacagcag aagctgataa tgatttcact
     4441 gatatcatag acaaacttac tgtctatccg gtacttaagt tccgtttgtg tggcaaaata
     4501 ttctaataat attctataaa ataaaaggag atgagcccta taattttcgc ctcatctcct
     4561 ttttatatat aagaaacaat acacttatat cagcaccacc atcacatcac gtgccccatg
     4621 agcacccatt accaaagcct gctcaatatc agccgtcttt gacggaccgg aaataaaggt
     4681 tccgaagcca tattcgcctg tatcaatcag tttatatgct tcatgcatat tgttcacaat
     4741 cttattcttg tttagaagaa taaccaattt ttcggcaata aaataaatgg cacgctgctt
     4801 tacatcctgt tctatccata ccgcaccatt ctccgcaacc ccaatctttc catctataac
     4861 ggccaaatcc gtcccattca gttctgcagg gtcttccaca tcatcgggat taaatgtcgc
     4921 acatgtaata gtcttcagat tagaagcgat gcgtttggct ccaggataag cctttttaat
     4981 gaaatcattc acgtcctcct ctttctccaa aagaatggct tcccctccta cctgcttcat
     5041 gatgagataa aactgttcca ccttactggg ataagttaat gccatatctt ccaatggctt
     5101 taaatccggt ttctcatatt ttacatgtgt agcacgccgg atgctctgca atatatcttc
     5161 tctgctgctc ataattactt cactttacct ttcttccaca tttcattgaa actctcctta
     5221 gcaaatttcg gcatctcacg cccttttccc cagtcattca atccgttata gataagaaaa
     5281 cgtggcattc cgtttaccaa tggcgcccat tttaatgcca tattgaatat caaagggcga
     5341 ttcatcatga attccatgcc accggacatt acccttttca tccggtctgc cttacccaat
     5401 ttatccaaat cctgacgcca cagatagatc tgctccgcca aatccacctt agccggacac
     5461 acaaacgaac aggaataaca caaagaacaa gccgacacat tgtcataata atgcaacggc
     5521 gccttcaaca ttcccaggtt aatcccgata gggccgggaa taaaataagt ataagagtac
     5581 cccccactac gtctatatac aggacatgta ttcatacagg ctccacaacg gatacaattc
     5641 aaagttttga tatgcttttg gtcggccaat atcttactac gtccgttatc tacaataata
     5701 atgtgaagct ccccaccctc tctaggcttt cggtaatgag aagtatatgt agtaatgggt
     5761 tgtcctgtag ccgaacgggc caacaagcgg gtgaacactc ctaaagattc acggtccggc
     5821 acaatttttt ccataccaaa agctgcaatc tgtaatttag gctgggaagt acccatatcc
     5881 gcatttcctt cattggtaca taccacaatc tcaccagtag aagctacagc aaagttagca
     5941 cctgtcatag ccgcctcagc atgaataaat ttctgacgga gattcttccg ggctgcatgt
     6001 gtaaggtaag tagggtcaaa atttcctttc tccgtaccca tctctcgctc gaaaagctca
     6061 cctacctgtt cacgtttgat atgaatagcg ggtaatacaa tatggcttgg cttcagatgc
     6121 atcaattgca agatacgctc tcccaagtca ctttctacca cttcaattcc tttgttttcc
     6181 aaaaaagggt tgagttcgca ttcctcggcc aacatggatt tgctttttat aaaatgcttc
     6241 actccgtgct ggttcagaat attgtagaca atattacaat actcatccgc gtcctttgcc
     6301 caatagacat gggctccatt agcacgcgca ttgttttcaa actccaccaa taattcatcc
     6361 aaatggctgt tactatatag tttagtagca catgccatat tacgcaattc ctcccattcg
     6421 ggaacttctt tactcagtct gtcacgcttt gccctaacca gccaaagtgt ttcgtcatgc
     6481 catgcggcct gtttcttgtt tttcagaaac tccgcagccg cttttgaatg tttcgtactc
     6541 ataatcctgc cgctaagatt tcaacaatgt gcaatgtctt gataggaagt ttgtcacggg
     6601 caatgatgcc attctgatgc atcaggcacg aactgtcggc ccccacaatg tattcagcac
     6661 cggtagcgat atgacgcatc accttgtcat gccccatctg cacggaaacc gcatcttcct
     6721 ctacggcaaa cataccgccg aaaccgcaac attcgtcttt acgttccggt tccacaactt
     6781 ccactccttc taccaaagag agcaaatcac gcagtttgct gaaataagga atattaagtt
     6841 cgctggcaga agaaagtttc atcaatctca ctccatgaca actgttttgc agactcactt
     6901 tatgtggaaa cttggctttc aacgaagaag gtctgacgat atcatgaata aactcacaga
     6961 tatcatatat cttaccttcg ctggcgcacc gatgtttgtc ttctttcaac aaacgactgt
     7021 agttatcacg cacaaaaacg acgcaactgg ccgaaggacc tactatataa tcgtaattct
     7081 taaactgttc gtcaaaatgg cgggctaaat ctaccgcttt attctcgaaa cctgcattcg
     7141 ccatcggttg accgcaacaa gtctggttga gaggataatc cacgtccact cccagacttt
     7201 tcagcagctt gtacgaggct atccccacct gcggatatac cgcattgata taacaaggaa
     7261 taaataaacc tactttcatt gtcattagtt aatatgtgtc ctatactgaa taacaaagtt
     7321 agaggatatt tgttaagaaa acaacgagat ttctaacgaa taatgaagcg gaataggtaa
     7381 aaaaacataa tattgtgggt aaaagcctta ctaataaaaa agcactcccc gcgaatcact
     7441 tcgcagggag tgcttttaac taataactaa ctttgtggtt tacgtaattt ctatatgact
     7501 aacttatagt gcaaagatag aggttagagg ccacatccac aatcacttca tttaggtatt
     7561 ctatcttatt ccactcacta tttataggta ttataagttc atcttcacct cgcttagttc
     7621 aaccagttta tttacgatag cgtaaatagt caatccggca ggtgaatgta tctgtagctt
     7681 gcgcgcaata ttccggcggt gagttatcac cgtatgaatg gagaggaaca gtttttccgc
     7741 cgtttcctta tttgtcattc cacgtaccac gcaacaaata atttctttct cacgctggct
     7801 caacgtttcc tgttcgccat ccgtctcatc cacaccaaga ttcatcagat ctactaactt
     7861 tttatttaaa acttcgatgt catcatacag cgctatactc tcatcgtaac ccttcaacaa
     7921 atttgtatct gtgactgaac acagcaaaga aacgcacttg gtagatgcct gtggatagtt
     7981 cgatttaaac tcgtccacgt taaaccatcc tccgaaagta ggatttataa ttagaatatc
     8041 cggctgatgt ccctgcatac aattctgcag tccttcaaga gaagttattt ccaccggctg
     8101 tattgtaaga tcaggcatgc gcttcagcac agccacaagt ccgctacgca caatgactga
     8161 cgtttcggcc accgcaacgt gcacaggttc tgtccgtttc atttcccctc cttttctagc
     8221 ctaagtacag caggcacaaa caagtagtcc tctacgcggc aatgggatgc caaatcttgt
     8281 tcacaactga atatgtcgaa taatacggcg ttcaacaaat ggttatttcc ttttgccgga
     8341 taatatttaa taatgatgtt ttttagctca gtcagtgtcg catctatctg atcatgcctg
     8401 cgggcaaact gtgagatacg gaatcctccc gtttctcgtc ctgccatcag attctctacg
     8461 taggtaaaca cattcatatc ttcataatcc atgtgtttac gcacttctcc ggcatactga
     8521 tcaaaaaatt tcaaaatgag aaatgcaacc tcattttccg tggaacaatc tatagcttct
     8581 atcagtttac gacgtatagt aggcagacag aaatcaagga aataatgatg tgcctgtttt
     8641 aaataattca tcaatgaagg catagaaatg tccttcacat cgtcctccat ccggtcgcta
     8701 tcttcaatca tgaagttcac caccgcaagg aaagtacgac aatccactcc attttcacgg
     8761 cacacctcct gtacagtctt gtctccaaac cccaacgaaa gatcaaaacg gctcattacc
     8821 tgtagcaatg tatagttatc acagataaga taactcattt tgtccgtcgg agtatattta
     8881 cttgttttat acatagttat gtttttggtt tctctttatg gccgcaaagt tacggaaaat
     8941 cactagggtt atcaatcact ataaataggt attttttctt gtaccccata attcccgttc
     9001 aactagccaa tgacagtctt ctaattatac attaatatat agccgttaag ataagtggca
     9061 agaatcaacc acaaaagata aggaacaaaa aggtatgccg aagatttctt caccggataa
     9121 ctttctatca tataataaac aacaagcaca tccagcacca aaatgtttgc aaaacctagc
     9181 aacggactcc ggagataaaa gaagaaaatg ctccatgtaa aattaaacaa gagctggaac
     9241 ccgaataatc tgataatcat ttgtcgtctt attgtccaca tatgccaaat caacccgata
     9301 gaaattccca tgcacagata gataaggctc caagcaatgg gaaaagccat atcaggtggt
     9361 gtaagagaag gtttgtccaa tgtaggatac cagttgagta tggcctccga ctgaaaataa
     9421 gaagcagtac agcctacacc aaaacagatg agtatggcaa tcagtatggg gattattttt
     9481 ttcataagga gaattatttc tatttatact atgattaaca aaccaatctc tggatttgtt
     9541 gcagaaacag aacacttctc ccatacaggt atctaaaaaa cgtgctccca ttcgttcgct
     9601 tacgatggga gcacttacaa cacaaaaact aaactagact taactaaact attctattaa
     9661 gaagtttcac aacttccctt gtctatgccg caaatataaa aagattattt ctttttagca
     9721 aaaggatatc gacaaaatat caacttttat cgttcaaata tcaacttttt caaacagaat
     9781 gactatttaa gtacatctgt aactcctgtt tataactatc ggaaatcgga atatactcct
     9841 taccgaaaac aatccgcccc cggtcaacca ccttgatttt actcttttgc actataaacg
     9901 agcgatgtac gcgaatgaaa cgactagaag gaagcttctc ttccatagct ttcatactga
     9961 caagtgacaa gatagctttc ggctcatcct ccacatgtat tttaatataa tccttcaacc
    10021 cttctatata tagtattcgg tctaaagcaa ttcggagcaa tttataatca ctttttacat
    10081 atatacaatc atccgcctca tcagcatcaa caccattatc tgccttctgt ttcagttcat
    10141 accattgcac cgctttattc accgattgca aaaaatcgac atagctgata ggtttcaaca
    10201 aatagtccaa ggcattgact ttataactat ccaaggcata ctgtccgaat gcagtagtaa
    10261 aaataatcct tgtttcggga ctgaccatgc gtgaaaactc caaaccgttc aactcgggca
    10321 tttgaatatc aaggaacaag acatgtacct cctcgcggag aggaatttct gtcatagctt
    10381 gcaccgcgct ggaatacctc cctaccaacc ggagaaaaga agttttttcc acatagcttc
    10441 tcagcaattc taaagccagc ggctcatcat ctacaatagc acaattcagt atcataagct
    10501 tttagtctgt atagttaata tagaagaata tacctgtccg ttctcactga tcccttttat
    10561 ccattcgtaa tgtcccggat aaatcagttc caaccgtttg cttacctgtt ccagccccac
    10621 cccgcttcca cttttatctt gcccagactt cggatgattg ctgttaagga tctcacatct
    10681 caccgtacca tccgtatgcc cgaagataga aatactgata aaactgtcta ccgtggggct
    10741 gatgccatgc ttgaacgcat tttctatcag tgatatgaaa ataaggggag cgatctgcaa
    10801 cgcacctccg gagtctacct ccaaattcac acttacttct acctgctgtg gcagacggat
    10861 acgcatcaaa gctacataat tacggataaa gtccaattct ttttcaagtg ggacaaaagt
    10921 ctgctgattg tcatagagca catgccgcaa caatttgctc agttcctgta ccgcctcctg
    10981 cgccttgtca ctgttaaaag caatcaaggc ataaatatta tttaatgtat tgagcagaaa
    11041 atgaggattc agctggttct tcaagttttt cagctccgct tccgtctttt gcctctcagc
    11101 ttctatcaaa cgctcttccg cctgacgcca acgcagactg gtacgaatgg ccgcacccaa
    11161 cccggcgaca aatatcatca tccccatatc ccgcgcatag aatatccatc gaggtggaat
    11221 atgacgcgca aattcaggag gcggaggcgt acttatactt tccagaaata catgaagaag
    11281 cacactcagg cagagtatca gcacggcatt gctcagaata tacttacgca tttcatccgt
    11341 gaacatatag cggggaacca gccacaagta attgacatag aagataacga aatagcacag
    11401 aggaacacaa ctgtgccgca agaattgggc caggttaaag ccgcttcccc ggtccataaa
    11461 gaccaacggg aagccaaata tgagcagcca actgacgata tggatgctca gttccaaaaa
    11521 acgtcgctgt gaaaataatt gtttcatata ggcaaagata agaaagatta ggttagaaat
    11581 aagatttcta cggctcttat tctgttattc atacgttcaa gtttggcttc ccacagctat
    11641 gggccgcgct cttcacagtt atggagagcg caacccatag ttatgaggag cgctctccac
    11701 aaccgtgggg aggcaaaccc gaacgtatgt tccggcattt ctctccatac agaaaacctt
    11761 ttccgccctt attcataacg caaagcgtct atcgggtcaa ggtctgcggc cttctttgcc
    11821 ggataccatc cgaagaacac accagtaacg gtacatacca gaaaggagag caacacgctc
    11881 caaggttgga taaacacagg ccaatgcgct attgccttaa tcataaagct ggctccgcaa
    11941 cctataatca ctcctatcaa gccacccgtg atactgatca ggatagcctc tatcaaaaac
    12001 tggctcagaa tatcgacccc tcgtgccccg accgacatgc gcagaccgat ttcacgggta
    12061 cgttctgtta cagacacata cataatattc atgataccaa tacctccgac taccagagag
    12121 atgccggcaa tacaagccag caaagtggtc atcaggtccg ttgtggtgtt gagcatactg
    12181 ctcagttcct gctgggtgcg gatggtaaag tcgtcagcgt ccgtttcttt cagcttatgt
    12241 tcacggcgca ggatggtcgt tatctcatct actgcttcct cggtcatttc ttctgtcaga
    12301 gccgaagcaa aaattccact taggtaagtc tgtgccagca gtcgtttcat caccgtgcta
    12361 taaggagcca gtaccacatc gtcctggtcc atgcccatcg agttataccc ttttgatttc
    12421 agcacaccga ttacccggaa aggaatctgg ttacaacgaa tcactttccc tatcggatcc
    12481 gatccgtcgg gaaaaagatt atcgacaatg gtcttgccga tgacacagac cttggctgac
    12541 gtacggatgt cattctcggt aaacatctcc ccctgttcca cggtgagctg gcgtatggta
    12601 agataatcca tacttacacc actcaccgaa gacgggtaat tgttggcccc cgcaacaagt
    12661 tgccccgaag aagaaacgtt gggactgatg ccggagagat aagtacactc ttcgctcaac
    12721 ttttcataat tttccagttt cagtgtctgc atggccgaag ggtcttggcg gacccctcca
    12781 cgcatctctg ctcccggatg aatcataatc atgtttgacc ccatctccga gatttgttgc
    12841 tggatgctct ttttcgagcc ctgaccgatg gcaagcatag caatgactga tgccacaccg
    12901 atgatgatcc ccaacatggt gaggaaagcg cggagcttgt tgttggcaag ggcccggaga
    12961 gctattttaa atagatttgt tccgttcata atgattcttt tttatggtta gtcctcgtca
    13021 ttcttgggca aggcagccag tgcggcagcg gccgaaagga tctgaggatt gacggtgtct
    13081 tccactacat gcccgtcacg caagcggata ttacggctgc tatactgggc tatttcggga
    13141 ttgtgagtga caaaaataag cgtacggcct tcggcgtgca acttttggaa aagcaccaga
    13201 atctcgaaag aggtacgggt atccagatta ccggtcgcct catcagccaa aataacggca
    13261 ggattattca ccaaggcacg ggcaatggcc acacgttgca tctgtccgcc ggacatctga
    13321 ttggatttat gttccagacg gtcacccagt cccacagcta tcagtgattc aatggcacgt
    13381 ttccgtcttt cggaagccga tacggacgag ttatacatca agggcaactc cacattctct
    13441 acggcagtcg tcttaggcaa cagattatag ttctgaaata cgaaacctat tttacgattg
    13501 cgcaacacag ccctctgagg tttgctcatg gtacgcacgg acacaccatc caacaggtat
    13561 tcaccactgg taggggtatc aagacatccc aaagtattca gcagagtgga cttgccggaa
    13621 ccggaagtac ccatgatcgt aacaaactct ccctc
//
