LOCUS       c00004_gnlPro..        14755 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|NPDLGOJE_4.
ACCESSION   c00004_gnlPro..
VERSION     c00004_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-07 17:10:22
            Original ID  :: gnl|Prokka|NPDLGOJE_4
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 14755
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..14755
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[276:4755]"
                     /cutoff="10000"
                     /detection_rule="(minimum(2, [Aminotran_5, GCV_H, GCV_T,
                     GDC-P, SoxG]) and GCV_H and GCV_T_C)"
                     /neighbourhood="10000"
                     /product="Glycine_cleavage"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      277..4755
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(2, [Aminotran_5, GCV_H, GCV_T,
                     GDC-P, SoxG]) and GCV_H and GCV_T_C)"
                     /neighbourhood="10000"
                     /product="Glycine_cleavage"
                     /protocluster_number="1"
     cand_cluster    1..14755
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(minimum(2, [Aminotran_5, GCV_H, GCV_T,
                     GDC-P, SoxG]) and GCV_H and GCV_T_C)"
                     /kind="single"
                     /product="Glycine_cleavage"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..14755
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Glycine_cleavage"
                     /region_number="1"
                     /rules="(minimum(2, [Aminotran_5, GCV_H, GCV_T, GDC-P,
                     SoxG]) and GCV_H and GCV_T_C)"
                     /tool="gutsmash"
     CDS             complement(45..218)
                     /locus_tag="ctg4_1"
                     /transl_table=11
                     /translation="MFKNRISNPKSTLYFEYKWVIKMKGEEKQGRRNVPFSFLIHTAFM
                     LNCFLDAFVSSD"
     CDS             complement(277..3123)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Glycine_cleavage: GDC-P"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Beta_elim_lyase"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg4_2"
                     /sec_met_domain="Beta_elim_lyase (E-value: 2e-09, bitscore:
                     30.6, seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="GDC-P (E-value: 1.4e-177, bitscore: 584.3,
                     seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNTHSDFASRHIGPQGEERREMLDSLGYRTLDELIADIVPADIRM
                     KAPLDLPAAKSETEALKELRSILRKNKLLKTFIGQGYYGTITPSVILRNVLENPGWYTA
                     YTPYQPEIAQGRLEMLMNFQTMVSSLTGLPVANASLLDEGTAAAEAVTMCRNARPKANT
                     FFVADTCHPQTISVIRTRAAFQGVNIIVGDCSSFDPASIGADLAGVLVQYPDTLGCICD
                     YTDFFSRVHATGALCVVAADLMALTVIREPGAFGADICIGNTQRFGVPMGFGGPHAAYM
                     SCTDALKRRMPGRLIGMSIDTLGRPAYRLALQTREQHIRRDKATSNICTAQVLLAVLAA
                     FYTVYHGQEGLKRIGTEIHLKTKSLYKALTEAGIAIENKNFFDTLLLSVPGQADAMVQK
                     ALEAGYNIRRVDADHAAISLDETATCADIAALASALAGAETSATCDCDAPAWDPVHTRQ
                     TPFCTEKAFNSYHSETEMMRYIRRLESRDLALNEAMIPLGSCTMKLNAASEMIPITWPE
                     ANSLHPFVPADQSEGIREMLSVLSDRLAKITGFAAVSLQPNAGAAGEYAGLLAIRRYQK
                     HAGEGHRNVCLIPTSAHGTNPASSAMAGLKVVPVKCDERGNINMADLKSQAEAHKDNLS
                     CIMVTYPSTHGVYEQTIKELCDIVHANGGQVYMDGANMNAQVGLTCPGCIGADVCHLNL
                     HKTFAMPHGGGGPGIGPIGVAEHLVPFLPGHLTLGHEEGAVASAAWGSASIAAICWMYL
                     SMMGPDGLREATEMAILNANYIAKKLGHLFPVLYSGNKGLVAHECILDPRQLTHDAGLT
                     VDDIAKRLMDYGFHGPTMSFPVPGTLMVEPTESEPKKELDRFIEAMERIHAEITAIING
                     TADKEDNVLKNSPHTAEMVSADEWRHPYSRSEAAYPVSGLLIHKFWPYVGRVDNVYGDR
                     NLVCTCDTVEEFSKAVEL"
     CDS             complement(3219..3599)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Glycine_cleavage: GCV_H"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg4_3"
                     /sec_met_domain="GCV_H (E-value: 3e-47, bitscore: 153.0,
                     seeds: 13, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MHDVPENLLYSKDHEWIEIDGDIGTIGISDHAQAELSDVVFVDLP
                     EVGATVAAGDPVAVVESVKAASDVYTPVSGEILEVNEELSNDPSLINSDPYGAGWLYKI
                     RLDVPTETEDMMNATDYEEYCS"
     CDS             complement(3670..4755)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Glycine_cleavage: GCV_T_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Glycine_cleavage: GCV_T"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg4_4"
                     /sec_met_domain="GCV_T (E-value: 5.9e-87, bitscore: 284.7,
                     seeds: 72, tool: rule-based-clusters)"
                     /sec_met_domain="GCV_T_C (E-value: 5.7e-23, bitscore: 74.2,
                     seeds: 348, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTDTDVKSTPLAAKHVELGARMVPFAGWNMPVQYTGILDEHKAVR
                     ETCGIFDISHMGQFTVAGGSAAAWLNSMLTNDINKLNVGQGQYSVMLNDRAGVIDDLIL
                     YRMEPETFFVVVNASKIDEDFAWLSAHQPAGVTLENHSDEYVGLAVQGPECGKVFSRVI
                     PGVELPPRNGISRITAEGTDLIICRTGYTGEDGFEFFCPAKEGVKWFEAFLGAGAKPCG
                     LGARDSLRLEMCYPLNGSDLSPDKTPLEAGLGFFCALDTDFIGSDILREQKANGLSRRL
                     AAIEYTGKGAPPRAHYAVHVPGGEAIGELTSGVLSPSLMKGIALAYLPAAHAKVGTELE
                     IDVRGRKFPAVVVKKPFYKKG"
     CDS             complement(4831..5952)
                     /locus_tag="ctg4_5"
                     /transl_table=11
                     /translation="MLQAGIVGLPNVGKSTLFNAVTRTRKAQAANYPFCTIDPNVGMVT
                     VPDPRLQVLSDMSGSEKIIPTLIEFVDIAGLVKGASEGAGLGNQFLANIREVDAIVQVV
                     RCFDNDDIIHELGSVDPLRDIDIINSELILADIATMEKRLSSRERKARSGDKEAKAEVA
                     LITKLLPHLNEGNPALTLEPQLDDDERKLLHSFQLLSDKKSIFACNVNEDELADAISNP
                     DAHPYVSQVKKYVAEHHNAEAIVISARIEEELIDVSEEESREFLESLGVKDSGVSDLIR
                     AVYHLLGLRTYLTTGIKETRAWTIPSGAKAPQAAGVIHTDFERGFIAAEVVHYDDLVSC
                     GGKAGAREHGKLRIEGKEYVVKDGDVIEFRFNV"
     CDS             complement(6011..6934)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_S11"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg4_6"
                     /sec_met_domain="Peptidase_S11 (E-value: 2.7e-54, bitscore:
                     177.6, seeds: 11, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRLFALLAGFSLCLSSTSCQSYGDSSDYIPLATPVPPQLSQPVSH
                     ALPRPANFPTRPVAIPSSAPRTPRCASACVMDALTGNVLFSHNGLQRRQVASTQKLVTA
                     MVVMGHGSLDKKVVIQPSDTKADPTKLGFRAGEVYSRRELLNAMMIRSFNDVALALARD
                     TAGSVPRFAQLMNAKARQMGMYNSRFANPNGLPADQYSTAIDMARCAYYVYRNPELRNI
                     ICKRQYAFTRANGRTLLLRNTNKLLTQNPWVTGMKTGYTNAAGRCLVSSAGVNGRHVIV
                     VVLGCHPSRIWTESENLIRWALGTAA"
     CDS             complement(7494..8621)
                     /locus_tag="ctg4_7"
                     /transl_table=11
                     /translation="MTPREAAIALNLIPGLGPVRIMRLLQVFASPELILESPSSLLMEI
                     PGVGAQLACRISSWRSIVNPYRELELADNAGAAVTTVFDDSYPSALRALPDPPIVLYSW
                     GNWTGTDAERSIAVVGSRMATHYGRLCARNISHDLAEAGVTVISGLARGVDTEAHTGAM
                     DAEGRTIAVIGAGLNKLYPRENRNLAQRIADGHGAVVSEFPMDLPPSRTTFPMRNRIVS
                     GWSRATLVVEASGRSGALITARTAAEQGREVFCIPGPVDRHSSDGCHALIRDGAILATG
                     ASDILQDMNWAVPEQGLPLFSPCSPAGASTPPLPTLEEKEILHAIRLGFNTIDTLCTSL
                     GKAAHTITPLLARMQIAGQITPDAGGYFSINSREL"
     CDS             complement(8618..9730)
                     /locus_tag="ctg4_8"
                     /transl_table=11
                     /translation="MKIVHLVPSMESGGVEQVVMELGSGLSSRGVENIVVSGGGRLVPR
                     LEKEGSRHILMPIGKKSISTLFRIGALRALLQAVRPDILHLHSRVPAWAGYLAWKKLPP
                     EDRPGLVTSVHGFYSVNRYSAIMSRGERVIAVSDCIRDYILDHYPSTPPDHIRIIPNAI
                     SPDQYHPAYSPSREWLTGWFMSYPELKGKFTLCLPGRITRLKGHLDLIPVVRQLLEQGI
                     PAHAVIVGEAKKGKEEYKNEVLRAIERSGVSQSFTWTGHRQDLREILSTCSVTLSLTKS
                     PEAFGKSTLEALALGKPVAGYAHGGVKEQLDAFLPEGNVAVGDTAAMADLLARWHAQPP
                     PLPRQIPSPYNMQDMIQAHLDVYQELTPYS"
     CDS             complement(9727..10743)
                     /locus_tag="ctg4_9"
                     /transl_table=11
                     /translation="MNKSMPPTKNFLLSGGNWIACTPPPLHNAAYMNIRILSDGKQGHL
                     NQSLGLAQALISKAGGTVETVDLQGLSLLGKIRKVVTGSDIPRPDLFISAGHATHIPLI
                     CARHHFKTRAVLCMKPTLPCSFFDLCLIPRHDLDSGRDYTDTDIFPTQGALHPMRPDPS
                     VPKDTTLILIGGPSKDFDWDDESMLNQLASISIHTPGHLVLTTSRRTPDGFAEKIRTAV
                     PELTVVPVEETRPGWVARHLAHASAAWVSQDSVSMVYEALGSGAPVGILSVPRRHGSRK
                     SRILSGLETLEKEGMVTGYSDWKKQNFRLTAPGSPLLEADRAADYILSRFFPQLRAL"
     CDS             10753..11814
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_16"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1019:4Fe-4S dicluster domain (Score: 66.5; E-value:
                     1e-20)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg4_10"
                     /sec_met_domain="Fer4_16 (E-value: 3e-20, bitscore: 66.5,
                     seeds: 227, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VLTPDSSVIKDSLCAVSRQLGFSGCRVARAEKSPHAEKLFQWLER
                     GWHAGMEWMARSPERRTDPAEVLPGCRSVICLSYDYDSPGRRPEGEGSICLYAHGKDYH
                     GILEEKLADLQELLSIYGGKQRGYVDSGPVMERDHAEACGLGWRGKSGLIVRRKGGSRF
                     FIATLLTTLELEPDAPVSNGCGSCRRCAALCPTGAIMENGQVDAGRCLSYWTIEHRGAI
                     PEEIRPLIGTRLYGCDTCVTVCPWNGKPLPDVDERFRMSRLLASIPLRGLLSLDAGGFA
                     ALFRNSPLKRLKREGLLRNGCIVLGNAGTPDDIDFLKALYGESPLVKEHASWAVERILR
                     RHGRHASSSGARD"
     CDS             11932..12309
                     /locus_tag="ctg4_11"
                     /transl_table=11
                     /translation="MARLFGTEIPNEKRIEASLPYIYGIGRSTSKRILEQAGINPDIRT
                     GQLTDEQLTKIVQVITTDGILIEGDLRREKQSILKRLTSINCYRGQRHRRGLPVRGQRT
                     RTNARTRKGKKKTVGAQAKKK"
     CDS             12343..12894
                     /locus_tag="ctg4_12"
                     /transl_table=11
                     /translation="MASEEITNETAEQPVEAAASAPVAETPAAAVSAPEEIKKPEPRKD
                     IFAELGLGGDDDKPKILKAKGSKNVSTGVVHVSSTFNNTVVTVTDQRGNVIGWSSAGKM
                     GFKGSRKSTAYAGQVVCQDACRQAMGHGLREVEVRVKGPGSGRESAVRAVQTIGIEITS
                     IKDVTPIPHNGCRPPKARRV"
     CDS             12930..13541
                     /locus_tag="ctg4_13"
                     /transl_table=11
                     /translation="MARYTGPRDKVSRRFGVALFGSTKALEKRPFPPGQHGMRAGRKKK
                     SDYGVMLAEKQKLRFQYGVLEGQFRKYYAEAARRRGITGDILLQLLELRLDNVVYRLGF
                     SNTRAGARQLVSHGHITVNGKKTNIASYSCRPGDVIAVGGKASSQQLVTRFLDLTQATV
                     VPDWLECDRDKLTGKIARVPSKEEIAPIVNEQLIVEFYSR"
     CDS             13672..14439
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HAD"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg4_14"
                     /sec_met_domain="HAD (E-value: 1.1e-35, bitscore: 117.2,
                     seeds: 107, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTDDWRKRGVALFDMDGTLLPWDTQYVFSCFVVRRHPWRRLLIFL
                     FLACIPLYILKIWDENRMKRAYLMYLWGLPAETVREYGRKFAEMAQEWIYPELKERLAG
                     YRKKGYLCLMVSASPSFYVKPLGELLGFDEVLGTDVLLEERMPAMPELPNGNNKGAVKV
                     ERLRERNVLPEHGVLENAVAYSDSAADLPMLLSCRRRVLVNPSPALKEDRLLDGAECLY
                     PARPWKGRFGKIWRIGFFVMGLVDVNNVKSMTC"
ORIGIN
        1 aagggcagag aaaaagctca tctgagacgt agctcaacgg atttctaatc cgaagaaaca
       61 aacgcatcca gaaaacaatt aagcataaaa gcagtatgta ttaaaaaaga aaaaggcaca
      121 tttctcctac cctgcttttc ctcccctttc attttgatga cccatttgta ctcaaaatag
      181 agtgttgact tcggattaga aatccgattc ttgaacataa gaaaaaggct gctccaaatg
      241 aatggaacag cctttttgaa aggaaggatg agatttttat aactctacgg ccttggagaa
      301 ttcctccacc gtgtcgcagg tgcagaccag attgcggtct ccgtacacat tatccacccg
      361 gcctacatac ggccagaatt tgtgaataag gagaccggag accggataag ccgcttcact
      421 gcgggagtag ggatgccgcc attcgtcggc agagaccatt tctgcggtat ggggcgagtt
      481 tttcaggacg ttgtcttcct tgtctgccgt accgttgata atggccgtga tttccgcatg
      541 aatgcgttcc atggcttcaa tgaagcggtc cagttctttt ttgggttccg attccgtcgg
      601 ctccaccatc agggtgcccg gaacggggaa ggacatggtg gggccgtgga agccgtagtc
      661 catgagcctt ttggcaatgt catccaccgt gaggccggcg tcatgagtga gctgacgcgg
      721 atccagaatg cattcatgcg ccaccaaccc cttgttgccg gagtagagaa ccgggaagag
      781 atgtccgagt ttcttggcaa tgtagttggc gttaaggatg gccatttccg tggcttccct
      841 gaggccgtcc ggccccatca tggagaggta catccagcag atggcggcga tggaggcgct
      901 tccccacgcc gcagacgcta cggccccttc ttcatggccc agcgtgaggt gcccgggcag
      961 gaagggtacg aggtgttccg ctacgccgat gggcccgatg ccgggaccgc cgccgccgtg
     1021 cggcatggca aaggttttat gcaggttcag gtggcagacg tccgcgccaa tgcagccggg
     1081 gcaagtcaga cctacctggg cattcatgtt ggcgccgtcc atgtacacct ggccgccatt
     1141 ggcatggacg atgtcgcaga gttccttgat tgtctgttca tataccccgt gcgtggaggg
     1201 gtacgtgacc atgatgcagg agagattgtc cttatgggct tccgcctggg atttcaggtc
     1261 tgccatgttg atgttgcctc tttcgtcgca tttgacgggt accaccttga ggccggccat
     1321 ggcagaggag gcgggatttg ttccgtgggc ggaggtggga atgaggcaga cattgcggtg
     1381 gccttctccg gcgtgcttct ggtagcggcg gatggccagt agcccggcat attcccctgc
     1441 ggcgcccgcg ttgggctgga gggaaacggc ggcaaagccg gtgattttcg ccagacggtc
     1501 ggacaggacg gagagcattt cccggatgcc ttccgactgg tccgccggaa caaagggatg
     1561 cagggagttg gcttccggcc acgtgatggg aatcatttca gaggcggcgt tcagcttcat
     1621 cgtgcaggag cccagaggga tcatggcttc atttagagcc aggtcccggg attccaggcg
     1681 gcggatgtag cgcatcattt ccgtttcgga atggtaggag ttgaaagcct tttccgtgca
     1741 gaaaggcgtc tggcgcgtgt ggacgggatc ccaggcagga gcgtcgcaat cgcaggtggc
     1801 ggatgtttcc gcacctgcaa gggcggaggc cagtgccgct atatccgcac aggttgcggt
     1861 ttcatccaga gagatggctg cgtggtcggc atccaccctg cggatgttat acccggcttc
     1921 cagggctttt tgcaccatag cgtccgcttg tccgggaacg gacagcagca gggtgtcaaa
     1981 gaagtttttg ttttcaatgg caatgccggc ttccgtgagc gccttgtaca ggcttttggt
     2041 tttcaagtgg atttccgtgc cgatgcgttt gaggccttcc tggccgtggt atacggtgta
     2101 aaaggcggca agcacggcca ggagcacttg ggcggtgcat atgttggagg tcgccttgtc
     2161 gcggcgaata tgctgttccc tcgtttgcag ggccaggcgg taggccgggc ggcccagggt
     2221 atctatggac atgccgataa ggcggccggg catgcggcgt ttgagagcgt ccgtgcagga
     2281 catataggcg gcatgggggc cgccgaagcc cattgggacg ccgaagcgct gcgtgttgcc
     2341 gatgcagata tcggctccga aggcgccggg ttcccggatg acggtaaggg ccatgagatc
     2401 cgccgccacg acgcagagcg cgcccgtggc atgcacgcgg gaaaagaagt ccgtgtagtc
     2461 gcagatgcag ccgagcgtgt ccggatattg gacaagcact ccggccagat ccgcaccgat
     2521 ggatgcgggg tcaaaggagg agcaatctcc cacgatgatg ttaacgccct ggaaggcggc
     2581 gcgggtacgg atgacgctga tggtctgggg gtggcaggtg tccgccacaa agaaggtgtt
     2641 tgctttgggg cgcgcattcc ggcacatggt gactgcttct gctgctgcgg tgccttcatc
     2701 cagcagggag gcgttcgcta ccggcagccc tgtcagggaa gagaccatgg tctggaaatt
     2761 catgagcatt tccagccgtc cctgggcgat ttccggttga taaggggtgt aggccgtgta
     2821 ccagccgggg ttctccagta cattgcggag gatgacggag ggagtgatgg tgccgtaata
     2881 gccctggcca atgaaggttt ttaggagctt gtttttccgc agaatggaac ggagttcctt
     2941 cagggcttcc gtttccgatt tggctgcggg caggtccagc ggggccttca tgcggatatc
     3001 tgcggggacg atgtccgcaa tgagttcgtc aagcgtccgg tagccgaggc tgtcaagcat
     3061 ttcccggcgt tcttccccct gggggccgat gtgccggctg gcaaaatctg agtgggtatt
     3121 catgtggtat ctctggctgg taatagcgtc cgaccgcgga acgggccaaa caaaatgccc
     3181 cgggatggaa tcaccggggc gggggaggga agaatggttc aggagcagta ttcctcgtaa
     3241 tccgtggcgt tcatcatatc ttccgtttcc gtgggaacgt ccaggcggat tttgtacagc
     3301 cagcctgcgc cgtaggggtc ggagttaatg agggacggat cattggaaag ctcttcgttc
     3361 acttccagga tttctcctga aacgggggtg tacacgtcgc tggcggcttt gacagattcc
     3421 acgacagcga cagggtcgcc agctgcgacg gtggcgccta cttcgggaag gtctacaaag
     3481 acgacatcgg agagttcggc ctgggcatgg tcggaaatgc cgatggtgcc gatgtccccg
     3541 tcaatttcaa tccattcgtg atctttggaa tacagcagat tttctggtac gtcgtgcata
     3601 agatgtaatt gtttgaagtg agagtgtagt aaaatgaggg gtttgtcagt ttatttttgc
     3661 gccgtagtgt cagccttttt tataaaaggg tttttttacg accacggctg ggaatttcct
     3721 tccccttacg tcaatttcca gctccgtgcc gaccttggca tgggcggcag gcaggtaggc
     3781 cagggcaatg cccttcatca gcgaaggaga gagcacgccg ctggtaagtt ctccgatggc
     3841 ttctccgccg gggacgtgca cggcatagtg ggcgcgggga ggagctccct tgccggtgta
     3901 ttcaatagcg gccagccgac ggctgaggcc gttggctttt tgttcccgga gaatatcgga
     3961 accgatgaag tccgtatcca gcgcgcagaa gaatccgagc ccggcttcca gaggcgtttt
     4021 gtccggagag aggtcggagc cgttcagagg atagcacatt tccagacgca ggctgtcgcg
     4081 ggcgcccagg ccgcagggtt tggctcctgc tccaagaaag gcttcaaacc atttgacgcc
     4141 ttccttagcc gggcagaaga attcaaaacc atcttccccg gtatagccgg tgcggcagat
     4201 aatgagatcc gtcccttccg ccgtgatgcg ggagattcca ttgcgggggg gaagttccac
     4261 gccggggatg acgcgggaga atacttttcc gcattcggga ccttgaacag ccagccccac
     4321 gtattcgtcg gagtggtttt ccagggttac gcctgcaggt tgatgggcgg aaagccatgc
     4381 gaagtcttca tcaatcttgg aggcattcac cactacgaag aaggtttccg gttccatccg
     4441 gtacagaatg aggtcgtcaa tgactccggc cctgtcattg agcatgacgg agtattgccc
     4501 ctgccctaca ttcagtttgt tgatgtcatt ggtcagcatg gagttcagcc atgccgcagc
     4561 ggaaccgccg gctaccgtga actgccccat gtgggagatg tcaaagatgc cgcaggtttc
     4621 gcgcactgct ttgtgttcgt ccagaatgcc ggtgtactgc accggcatat tccagccggc
     4681 gaaaggaacc attctggctc ccagttcaac gtgtttagct gccagggggg tggatttgac
     4741 gtctgtatca gtcatgaggc gatgtgaagg ttgtgagcaa tctgcccctt atatcagtaa
     4801 aagtcaatgg aattccggta acgcttccgt ctagacattg aagcggaatt cgatgacgtc
     4861 cccgtctttg acgacatatt cttttccttc gatgcgcagc ttgccgtgtt ccctcgctcc
     4921 ggccttgccg ccgcaggaaa ccaggtcgtc gtagtgcact acctccgcgg cgataaaacc
     4981 gcgttcaaag tccgtgtgga taacgccggc cgcctgaggt gcttttgccc cggacggaat
     5041 ggtccaggcc cgcgtttcct tgattcccgt ggtaaggtag gtgcgcaggc ccagaaggtg
     5101 gtacacggcg cggataaggt cggaaacgcc ggagtccttc acacccaggg attccaggaa
     5161 ttcgcgggat tcttcctccg agacgtcgat gagttcctct tcaatccggg cggagatgac
     5221 aatggcttcc gcgttatggt gttccgctac gtattttttc acctgggaga cgtagggatg
     5281 ggcgtccggg ttggagatgg cgtccgccag ttcgtcttca ttgacattgc aggcgaaaat
     5341 gcttttttta tccgaaagca gctggaagga atggagcagc ttgcgttcat cgtcgtccag
     5401 ctgcggttca agggtgaggg ccggattgcc ttcgttcagg tggggcagga gtttggtgat
     5461 gagggccact tcggccttgg cttccttgtc gccgctgcgt gccttgcgtt ctcgggaaga
     5521 gagtctcttt tccatggtgg cgatatccgc cagaatgagt tccgagttga tgatgtcaat
     5581 gtcgcgcaga ggatccacgg aaccgagttc gtgaatgata tcatcattgt caaagcagcg
     5641 gactacctgc acgatggcat ccacttcacg gatgttcgcc agaaactggt tgcccaggcc
     5701 ggctccttcc gaggctccct tgaccagacc ggcaatatcc acgaattcaa taagcgtggg
     5761 gatgattttt tcagaaccgg acatgtcgga aagaacctgc aggcggggat ccgggactgt
     5821 taccataccc acgttcgggt caatggtgca gaagggatag ttggccgcct gggccttgcg
     5881 cgtccgggtg accgcattga atagagtgga tttgccgacg ttggggagac ctacaatacc
     5941 tgcctgtaac ataggcagga ctgatagcgg gtcacgccgt gaaagtcaaa taccaattgc
     6001 cgacgggcat ttatgcggcg gttcccagag cccatctgat caggttttcc gattccgtcc
     6061 agatacggga cggatggcag ccgaggacga cgacgatgac atggcgcccg ttgacgccgg
     6121 ctgaggaaac caggcagcgt ccggcggcgt tcgtgtatcc ggttttcatt ccggtaaccc
     6181 aggggttctg ggtgagcagc ttgttggtgt ttctcagcag aagcgttctg ccgttggcgc
     6241 gggtaaaggc atattggcgt ttgcagataa tattgcgcag ttccgggttg cggtacacgt
     6301 aataggcgca gcgggccatg tcaatggcag tggaatattg atccgccggg aggccgttgg
     6361 gattggcgaa gcgtgagttg tacatgccca tctgccgggc tttggcattc atcaactggg
     6421 cgaaacgggg aacggaacca gccgtatcgc gggccagagc cagggctacg tcgttgaaac
     6481 tgcggatcat catggcattg agcagttcgc ggcgtgaata gacttccccc gcccggaatc
     6541 ccagtttggt ggggtccgcc ttggtatcgg aaggctggat gaccactttt ttgtccagac
     6601 tgccgtgtcc catcacgacc atggccgtca cgagtttctg cgtgctggct acctggcggc
     6661 gctggaggcc gttgtgggaa aagagcacgt tgccggtaag ggcgtccata acgcaggcac
     6721 tggcgcagcg gggcgtgcgc ggggcgcttg aggggatggc tacgggacgt gtggggaaat
     6781 tggccggtcg ggggagggca tgggaaaccg gctgggagag ttgtggggga acgggcgttg
     6841 cgagggggat gtagtcactt gaatccccgt acgattggca gcttgtggag ctcaggcaaa
     6901 gggagaatcc tgcaagaagg gcgaataaac gcatgtcttg ttgctacagt aagaagtttc
     6961 gttcatcaag cccaaactcc gcatttgaaa gagagccgga cgaaaaaggc cgcggatcgg
     7021 acaatccgcg gccttttttc tctattaact acctatggaa ccaaaaacca ccctgaacgg
     7081 attttgaatt gctttttcca tccgtcggac agatcttgtg aaggatgaga ctacaggaag
     7141 gaggtatgtg ttcaaaatat gttcgtcaac agttctttta agaggtgttg ccgtatgcgc
     7201 ccgagcctgc gtccagtaaa tatggcagag attttttccg aacatatttt gtttttcgcg
     7261 ggcatgtaaa ttttgccgca ggcatttaaa atgccgggga tgtcctgccg atatatttaa
     7321 tttttggaat aaaattattg aaggaaagga tttggcgact gttttaagac gtttttttgc
     7381 atccggatgg aaaggttttt atacgggaga tggacggcgc tcccttccgg ttccatggtc
     7441 agggagagga ggcccggact tggcgttttc cccggcggaa aagcggaatc tgcctaaagt
     7501 tccctgctgt taatggagaa ataccctccg gcgtccggag taatttgccc tgcaatttgc
     7561 attctggcca aaagcggggt gatggtatgc gccgcttttc ccagagaggt gcagagggta
     7621 tcaatagtat tgaaacccag tctgatggcg tggagaatct ccttttcttc caaagtggga
     7681 agcggtgggg ttgaggctcc ggcaggggag catggcgaga agagaggcag tccctgttcc
     7741 ggaacggccc agttcatgtc ctgcagaata tcggaggctc cggtagctag gatggctccg
     7801 tcccggatga gggcatggca tccgtcggaa gaatgccggt caaccggtcc gggaatgcag
     7861 aaaacctctc ggccctgttc ggccgccgtt cgggccgtga tcagggcccc gctgcgtccg
     7921 gacgcctcca ccaccagcgt ggcgcggctc cagccgctca cgatgcggtt gcgcatggga
     7981 aaagtggtgc gggagggggg caggtccatc gggaactcgg agactaccgc tccatgcccg
     8041 tccgcaatgc gctgcgccaa gtttctgttt tcccgaggat acagtttgtt gagtcctgcc
     8101 ccgataacgg cgatggtgcg cccctccgcg tccatggccc cggtatgggc ttccgtgtcc
     8161 acgccgcgcg ccagtccgga aatgacggtg actccggctt ccgccaggtc atgggagatg
     8221 tttctggcgc agagcctgcc gtaatgggtg gccatccgtg agccgacgac ggcaatggag
     8281 cgttcggcat ccgttccggt ccagtttccc caggagtaga ggacaatggg cgggtctggg
     8341 agagcacgca gggcggatgg gtaggagtcg tcaaaaaccg tggttaccgc ggcccccgcg
     8401 ttatccgcca gttccagttc cctgtacggg ttgacgatgc tccgccaaga ggaaatgcgg
     8461 caagccagct gcgcccccac gccgggaatt tccatcaaca gggaggaagg ggattccaga
     8521 atcagttccg gagaggcgaa tacctgcagg agacgcatga ttctgacagg gcccaggccc
     8581 ggtatcaggt tcagggctat ggctgcttcc cggggtgtca tgaataaggg gtcagttcct
     8641 ggtaaacgtc cagatgggct tgaatcatat cctgcatatt gtaaggggaa ggaatttgcc
     8701 ggggcagggg ggggggctgg gcatgccagc gggccagcag gtccgccatg gcggcggtat
     8761 ctcctacggc gacgttccct tcaggaagga aggcgtccag ctgttccttg actccgccgt
     8821 gggcgtatcc ggccacgggt ttgcccaggg cgagcgcctc cagggttgat ttgccgaagg
     8881 cttccgggct tttggtcagg gagagggtga cggaacatgt ggaaaggatt tccctcagat
     8941 cctggcgatg tcctgtccag gtgaaggact gggagacgcc ggaacgttct attgcccgca
     9001 ggacctcgtt tttatattct tcttttccct tctttgcttc tcctacaatg acggcgtggg
     9061 ccgggattcc ctgttccaga agctgcctga cgaccggaat cagatccaga tgccctttca
     9121 ggcgcgtgat gcggcccggc aggcacaggg tgaatttccc cttcagttca ggataggaca
     9181 tgaaccagcc cgtgagccat tcccgggagg gggagtaggc cgggtgatat tggtccgggg
     9241 aaatagcatt gggtatgatt ctgatatggt ccggaggggt ggacggataa tggtcaagga
     9301 tgtagtccct gatgcagtcg gagacggcga tcaccctctc tccccggctc atgatggcgg
     9361 agtaccggtt gacggagtag aagccgtgaa cgctggtgac gaggccgggg cggtcttccg
     9421 gcgggagctt tttccatgcc aggtagcctg cccacgcagg aacgcgggaa tggagatgca
     9481 ggatatccgg cctgacggcc tgaagcaggg cgcggagggc cccgatgcgg aagagagtgg
     9541 agatgctttt tttgcctatc ggcatcagga tgtggcggga gccttccttt tccagacggg
     9601 gcaccaggcg tccgcctccg gaaacgacga tattttccac gccccgggaa gaaaggccgc
     9661 tgcccagttc cataacgact tgttccacgc ctccggattc catggagggg acgagatgta
     9721 ctattttcat aaggcgcgga gctgagggaa aaatctggag aggatgtagt ctgctgcacg
     9781 gtccgcttcc agaagcgggg aaccgggagc cgtcaggcgg aagttctgtt ttttccagtc
     9841 actgtatcca gtaaccatgc cttccttttc cagtgtctcc aggccggaca ggatgcggga
     9901 tttgcggctg ccgtgtcggc gcggtacgga aaggatgcct acaggcgcgc cggagccaag
     9961 agcctcatat accatggaga cgctgtcctg gctgacccag gcggcggagg cgtgcgccag
    10021 atgccgggct acccaccccg gccgggtttc ctccacggga acgacggtta gttccggaac
    10081 ggccgtccgg attttttccg caaagccgtc cggcgtccgg cgcgaggtgg ttagaacaag
    10141 gtgtccgggg gtgtggatgc tgatggacgc gagctggttg agcatgcttt cgtcatccca
    10201 gtcaaaatct ttgctgggcc ctcctatgag aatcagtgtg gtatcctttg gtacggaggg
    10261 atccggcctc atggggtgga gagctccctg ggtggggaag atatccgtat ccgtgtaatc
    10321 gcggccggaa tccaggtcat ggcggggaat aaggcagagg tcgaaaaagg agcagggaag
    10381 cgtaggcttc atgcagagga cggcccgggt tttgaaatgg tgccgtgcgc agatgagcgg
    10441 gatatgcgtt gcatgtccgg cggaaatgaa cagatccggc cgtggaatgt cgctgcctgt
    10501 gacgaccttc cggattttcc ccaaaaggga aagcccctgc aggtctaccg tttccacggt
    10561 tccccccgct ttggagatca gagcctgcgc cagccccagg gactggttga ggtggccctg
    10621 tttcccatcg ctcagaatcc ggatgttcat atatgcggca ttatgaagcg gcggcggggt
    10681 gcaggcaatc caatttccac cggacagaag aaaattcttg gtgggaggca tgctcttgtt
    10741 catgattccg gcgtgctgac tccggattcc tctgttatta aagattcctt gtgcgccgtg
    10801 tcccggcagc ttggtttttc cggctgccgg gtggcccgtg cggaaaaaag cccgcatgcg
    10861 gaaaaattgt ttcaatggct ggagcgcgga tggcacgccg ggatggagtg gatggcgcgt
    10921 tccccggagc ggcgcacgga tcctgcggaa gtgcttcccg gatgccgttc cgtcatttgc
    10981 ctgtcctatg attatgacag ccccggtagg cgcccggagg gggagggtag catttgcctt
    11041 tacgcccatg gaaaggatta ccacggaatt ctggaggaaa aactggcgga tttgcaggag
    11101 ctgctttcca tttacggcgg gaagcagagg gggtatgtgg actccggccc tgttatggaa
    11161 cgggatcatg cggaggcctg cggcctgggc tggcgcggga aaagcggttt gatcgtgcgc
    11221 aggaaagggg gctcccgctt ttttatcgct accctgctga ctacgctgga actggaaccg
    11281 gacgctccgg tttcaaacgg atgcggcagt tgccgccgtt gtgcggccct gtgtccgacg
    11341 ggcgcaatta tggaaaacgg tcaggttgat gccggacgct gcctttccta ctggacgatt
    11401 gaacaccggg gggctattcc ggaagaaatc cgtcccctga taggcacgcg cctgtacggg
    11461 tgcgatacct gcgtgacggt ctgtccctgg aatggtaagc ctttgccgga cgttgacgaa
    11521 cggttccgca tgtcccgtct gctggcttcc attcccctgc gcggtcttct ttccctggat
    11581 gccggcggtt ttgcggccct gttccggaat tccccgttga aaaggctcaa gagggaaggg
    11641 ctgctgcgta acggctgcat tgtgctgggg aatgcgggga ctccggatga cattgatttt
    11701 ctgaaggcgc tttacgggga gtctcctctg gtgaaggaac acgcttcctg ggctgtggag
    11761 cgcatcctcc gccgccacgg gcggcatgca tcttcaagcg gtgcaagaga ttaaaaataa
    11821 aaaaatgatg ttttggtctt gtcaaaacct caatttatgg tatccatctt gccccaagca
    11881 atagctctgc gcgaggcaga gaaaaataac agctagcaaa tccaatccat tatggcacgc
    11941 cttttcggta cagaaatacc caacgagaag cgcatcgagg cttcccttcc gtatatttac
    12001 ggaattggtc gctcgacttc taagagaatc ctggaacaag caggcatcaa tcccgacatc
    12061 cgcacgggac agcttaccga cgaacagctc acgaagattg ttcaagtaat caccaccgac
    12121 ggcattttga ttgaaggtga ccttcgtcgt gaaaagcaat ccattctcaa gcgtctgacc
    12181 tccatcaact gctatcgtgg tcagcgccac cgccgcggcc ttccggtacg cggtcagcgt
    12241 acccgcacga atgcccgcac ccgtaaaggc aagaagaaga ccgttggcgc gcaggccaag
    12301 aagaagtaat ccgccaacct gaatttttaa tatagcttta ctatggctag cgaagaaatc
    12361 accaacgaaa ccgccgaaca gcctgtggaa gcggcagctt ccgctcccgt cgctgaaact
    12421 ccggccgccg ctgtttccgc tcctgaagaa atcaagaagc ccgaaccccg caaggatatc
    12481 tttgcggaac ttggtctggg cggcgatgat gacaagccca aaatcctgaa ggccaagggc
    12541 agcaaaaacg tttccacggg cgtggttcac gtttcctcca cgttcaataa caccgtcgta
    12601 actgtgactg accagcgcgg caatgtcatc ggctggtcct ccgccggcaa gatgggcttt
    12661 aagggttccc gcaagagcac ggcctatgcc gggcaggtgg tgtgccagga cgcctgccgc
    12721 caggccatgg gtcacggctt gcgtgaagtg gaagtgcgcg taaaggggcc cggttccggt
    12781 cgtgaatccg ccgtacgtgc cgtgcagacg atcggtattg aaatcacctc catcaaggac
    12841 gtgaccccca tcccccacaa cggctgccgt cctccgaagg cccgccgcgt ctaattgaga
    12901 atcttttacc tatatagatc taatatatca tggctcgtta taccggtccc cgcgataaag
    12961 tgtcccgccg ttttggcgtt gcccttttcg gttccaccaa ggctcttgaa aagcgcccct
    13021 tccctcccgg ccagcatggc atgcgcgccg gccgcaagaa gaaatccgac tatggcgtga
    13081 tgcttgctga aaaacaaaaa ctgcgtttcc aatacggtgt gcttgaaggt cagttccgca
    13141 agtattatgc agaagccgcc cgccgacgcg gcattaccgg cgatattctg cttcagctcc
    13201 ttgagcttcg tctggacaat gttgtgtacc gcctcggctt cagcaatacc cgtgccggcg
    13261 cccgtcagct tgtttcccac ggccacatca ccgtgaacgg caagaagacg aatatcgcgt
    13321 cctactcctg ccgtccgggc gacgtcattg ccgtaggcgg caaggcttct tcccagcagc
    13381 tggttacccg tttccttgac ctgactcagg ctactgtggt tcctgactgg ctggaatgcg
    13441 accgtgacaa gctcacgggc aagattgccc gcgtgccttc caaggaagag attgctccca
    13501 tcgtcaacga gcagctcatc gtggaatttt actcccgtta atcttatttc cttctggatt
    13561 tgcttcaaaa ccccggttgc ctttcggtgg ccggggtttt gggcattcag ggggagggcc
    13621 atggaagagt tggatgttga gagttaaggg aagcggttat aggatgaaag catgacggac
    13681 gattggagaa aaagaggcgt agcgctgttt gatatggacg gcacgctcct tccctgggat
    13741 acgcaatatg ttttttcctg ttttgtggtg aggcgccatc cttggagacg cttgctgatt
    13801 tttcttttcc tggcttgtat cccgctctat attttgaaaa tatgggatga gaaccggatg
    13861 aagagggctt atctcatgta tttgtggggg cttcccgctg aaacggtgcg ggaatatgga
    13921 cggaagtttg ccgagatggc gcaggaatgg atttatccgg agctgaagga gcggctggca
    13981 gggtatcgga agaagggtta tttgtgtctc atggtttccg cttctccatc attttacgtg
    14041 aagcctctgg gcgaactgct gggatttgac gaagttctgg gaacggatgt gcttctggag
    14101 gaacgcatgc cggcaatgcc ggaactgccg aacggtaata ataagggggc ggtgaaggtg
    14161 gagcgtctgc gggagcggaa tgtactgccg gaacatggtg ttctggaaaa cgccgttgcc
    14221 tacagcgaca gtgccgcgga tctgcccatg ctgctttcct gcaggcggag ggttctggtg
    14281 aatccttctc ctgccctgaa agaagacagg cttctggatg gtgcggagtg tctgtatccg
    14341 gccaggcctt ggaagggaag gtttggcaag atatggagaa ttggattttt tgtcatgggg
    14401 ctggtggatg taaataatgt gaaatcaatg acttgctgat ttatcaagag aaaattcttt
    14461 acttttgtga cgaaaatgtt tcacttttct taacaagggg ggaaaaagca tttttctttc
    14521 catgttagca aatcaacaat taatacccta accaagtaat agtcatgcaa accaagaaca
    14581 tcatcagtgt tgcggcagtt gtagcatcct ttgccggagc tgctcttgcg ggtactcccg
    14641 tcaagattgt tgctccgact ccggttcccg ctcctgtggc gacttccagc ccgctgtccg
    14701 gcgatattta cgccggctac gcttccaatt acacctgccg cggcattgtg gcttc
//
