LOCUS       c00033_gnlPro..        15750 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|HDHPLAAC_33.
ACCESSION   c00033_gnlPro..
VERSION     c00033_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-05 16:59:58
            Original ID  :: gnl|Prokka|HDHPLAAC_33
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 12163
            Orig. end    :: 27913
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..15750
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[22163:24359]"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..12196
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
     cand_cluster    1..15750
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /kind="single"
                     /product="Fumarate2succinate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..15750
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Fumarate2succinate"
                     /region_number="1"
                     /rules="(Succ_DH_flav_C and FAD_binding_2 and (Fer2_3 or
                     Fer4_7 or SucD_FumR))"
                     /tool="gutsmash"
     CDS             complement(968..2566)
                     /locus_tag="ctg33_12"
                     /transl_table=11
                     /translation="MNNETFEMVAKTLYGLEEILAGELLAIGANDIEIGRRMVSFTGDK
                     EVLYRANFCCRTALRILKPIYHFKAKDADTVYKEVKKVVWENYMSLDKTFAIDSVIYSE
                     DFNHSKFVAYRTKDAIVDYFMEKHNKRPSVRVNNPDLYINIHISHNDCTLSIDSSGESL
                     HKRGYRVEQTEAPLNEVLAAGMILKTGWKGESNFVDPMCGSGTLLIEAAMIALNIAPGI
                     HRKEFAFEKWIDFDQELFDRIYNDESQEREFTFKCYGSDINPAAIEIAQKNIRSAGLAK
                     YVELKTMPFQQYTEAPQPGILVTNPPYGERISSRDLLGLYNMIGERVKHVFTGYKVWIL
                     SYKDECFDKIGLRPSERMKLINGSLDCEYRCYEIFEGKNKDYKKALNEEGAERTEDSAS
                     RPRPSFPEKRYDTRPAGRPNFKTDRMDRPDRRFAAAHSEDENERTSAAPGKRFFGEERG
                     DGRPARKQFGGERGERPVRPILHKAGEKRPVKMRYKDEDDRFSKNRKNFGDRKRGEGRP
                     FKKPFRREDNDDFED"
     CDS             complement(2592..3491)
                     /locus_tag="ctg33_13"
                     /transl_table=11
                     /translation="MGLQKHSKVLNETVEKLSDECSYKQLFHAYRDEEALPSGEVLEEI
                     IDLCRAILFPGYYGNARISTQTIRFHTGVNIEKLHELLSRQIYAGLCLADTSCTSCAEE
                     LIFSQAEKLSEAFISTLPEMRCLLATDAEAAYNGDPAAQNINEVIFCYPGFRAIGNYRI
                     AHQLYKLGVPFIPRMITEMAHSETGIDIHPGAQIGHYFSIDHGTGTVIGETSVIGNNVR
                     IFQGVSLAGEKLPPDENGNAIRGVPRHPILEDNVTVYSNATLLGKIRVGKGATICGNVW
                     ITGDVPPGAVITQNKVTK"
     CDS             complement(3550..4020)
                     /locus_tag="ctg33_14"
                     /transl_table=11
                     /translation="MKNLLAIFLMVFLFASCEGPMGPPGRDGEDGGITYWIFDKDIQVK
                     SSDWELVDNGNNEPFYMYEYRIADKDFDIYQDAYKEGLITCYMYLDHGEDKEAQTALPN
                     PVNRIDKENNIWTETYAAEYTKDGFIIFKVTFSDFFTDQRPPETHFKAVITY"
     CDS             complement(4041..4406)
                     /locus_tag="ctg33_15"
                     /transl_table=11
                     /translation="MNFGYRNGVIYLHSAQEGRSISILERNPKVCITFSTDHDLVFQHP
                     EVACSYRMRSKSVIAWGKVRFEEDFDKKTEALDIIMKQYSDKEFRYSDPAVKNVKIWLV
                     DLDEVTCKEFGAPHKKY"
     CDS             complement(4718..4933)
                     /locus_tag="ctg33_16"
                     /transl_table=11
                     /translation="MKNLLILSKKVILNRPWDLKSHAKQHILSPERVNIQTKPEQHIHI
                     FQMYFTTFINNYHTSSNIKPHLLINN"
     CDS             5248..7071
                     /locus_tag="ctg33_17"
                     /transl_table=11
                     /translation="MNKTILLVVFCFSLFVSGYSQGIRFDSYPSHPRLLVKKGEEQKIK
                     SDLALNPEMLRLHNYLLKQCDDLITTPVLAYKKEGKRLLAVSREALRRIFYLSYAYRMT
                     GEDKYRLRAEQEMIAVCSFADWNPSHFLDTGEMTMAVAIGYDWLFDRLSPDARRLVQEA
                     ILNKGFAPSRDKRYNWFLRATNNWNQVCNAGLVYGALAVLEDHPEEAREIIERALSTVG
                     LTLKGYGPDGAYPEGYNYWGYGTTFQVLLNAALESALGTDGGLSSAEGFLASARFMQFM
                     TGTTGKCFNFSDSRESVFALPAMYWFADKLQDPTLLWNEKDMLSRAELSFSDEESRFLP
                     LIPIYGSQYKMNELVPPAMKLWAANGQTPVVLVRTGWENGEGFYLGIKGGTASTSHAHM
                     DAGSFVFDALGVRWVQDLGMQEYYSLEKENVDLWNMSQNGQRWNVFRYNNLAHNTLTVN
                     GKYHDVNGFVPVTNIYSEAHKLGASLNMTDLFGGELENAVREVALINEKYLSVIDRVKA
                     GSQPATVRWTIVTGAIPRVLDSHMVELTKDGKCMQLIVDSPSVTSVSVLDNVSKNSYDA
                     SNEGTCRIVFDVSLESGQESDIKVRLVPAAD"
     CDS             complement(7075..8322)
                     /locus_tag="ctg33_18"
                     /transl_table=11
                     /translation="MLRVPVPLFAISAITYGQGDKFRTLRNTHTPNFHYRYDDFLQYTP
                     LLAVYGMKLGGVESRSSWPRMIVSNAFSATIMAATVNSMKYTIKRERPDGSKNNSFPSG
                     HTATAFMAATIMHREYGLTRSPLYSIGGYTVATATAFSRQLNNRHWLSDVLAGAGIGIL
                     STELGYFLADLIFKDKGLNLPDKLRESAPKGGRPSFLEFAVGYSIINGSIEVGKNIRLS
                     SPGATNVSVKGGYFFNPYFGIGGEITALASPMAFDMSLYTGTTPSTKYDITRVHADPTG
                     VFTFTAGPYFSLPVASKLLLGTKFQAGYSYLVKNEVEMDLQEKPPSYGTINNIVFMKGN
                     GSSNYVLRTGISATGIVSRNLGIRMFVDYDYTFLKAPYEILTSLRDSQPVYGESHLSKH
                     KIHYFTIGATVTALFW"
     CDS             complement(9107..9688)
                     /locus_tag="ctg33_19"
                     /transl_table=11
                     /translation="VCATGRILDTEVQYVESHFCQRGSSRSTGQTSTNYNHVQTTFVRG
                     VHQFLMIFIIFPLLSQRALRDFRIYLSHNDLFSILLHLKLMSCTNSYIVTTYTIQVEND
                     SNDSKHYANNGCYNLGNADPTVHPDRVTPTDSLNSAPEPVSQVEPQSYVPYQIQHCIQD
                     ITLEIVVDKRCTVLRRYGCCSVAKCYHVIA"
     CDS             10001..11413
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Succ_DH_flav_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: FAD_binding_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1027:FAD binding domain (Score: 111.5; E-value:
                     1.7e-34)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg33_20"
                     /sec_met_domain="FAD_binding_2 (E-value: 6.8e-35, bitscore:
                     111.5, seeds: 62, tool: rule-based-clusters)"
                     /sec_met_domain="Succ_DH_flav_C (E-value: 1.1e-38,
                     bitscore: 122.9, seeds: 739, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIGLNKVKMYTRHEMLDVVKVDGRARGIIARNLITGQIERFSAHA
                     VVVATGGYVNTFFLSTNAMASNGSAAWQCYKKGAYFANPCMVQIHPTCVPVKGDYQSKL
                     TLMSESLRNDGRIWVPKKLEDAKALQAGTKKGKDIPEADRDYYLERRYPAFGNLVPRDV
                     ASRAAKERCDAGFGVNNTGLAVFLDFSDAINRLGKDVVKAKYGNLFDMYEEITNDDPYE
                     TPMMIYPALHYSMGGLWVDYELMTSIPGLFAIGEANFSDHGANRLGASALMQGLADGYF
                     VLPYTIQNYLSDQIQVPRFSTDLPEFAEAEKGIKDRIKKLMSIKGKESVDSIHKKLGHI
                     MWEHVGMARDAKGLQEAIQMLKELKKEFWSNVYIPGEADNLNVELDKALRLADFIEIGT
                     LMAHDALDRAESCGGHFRTEHQTEEGEALRHDDKFMYVSCWEYQGEDKDPVMLKEDLNY
                     QFVVPQTRNYKK"
     CDS             11441..12196
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Fer2_3"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_8"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg33_21"
                     /sec_met_domain="Fer2_3 (E-value: 1.7e-26, bitscore: 83.2,
                     seeds: 38, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_8 (E-value: 5.6e-12, bitscore: 36.8,
                     seeds: 153, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 6e-06, bitscore: 17.5,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDKDIKVTLKVWRQKSPKDKGQFETYQIDKINQSVSFLEMLDILN
                     ERLVSEGKEPIVFDHDCREGICGMCSLYVNGHPHGPATGATTCQLYMRRFNDGETITIE
                     PWRSAGFPVIRDLMVDRYAYDKIIQAGGFVSVNTGGVPDANSIAIPRADAEMAMDAAAC
                     IGCGACAAACKNGSAMLFVSAKVSQLALLPQGKVEAARRAKAMVAKMDELGFGNCTNTR
                     ACEMECPKNISVSNIARLNREFICAKLQD"
     CDS             complement(12495..13340)
                     /locus_tag="ctg33_22"
                     /transl_table=11
                     /translation="MEDNIPKFDLPVDFIVGNSITGEILNQYGRFPCKIKAGIFVLCVQ
                     GTVHATVNLTEFTIRKNDFITLPPGCFIQIHEVSDDVKLCFAGFSSVFVSHINYIKTIT
                     NYLPVIFDSPIMPLPEHISLLYQQAFDLLINAYSMPKTIENKEIIKAIFTIFMQGVIEL
                     YRNHTPYSNAPMTRNMEICREFVQLAMENYTKEHSVSYYAKRLNITLQHFCYVIKKVSG
                     RTALDILSNIIIMDAKAQLKSTDMPVKKIAFALGFDNLSFFNKYFRQHVGMTPQEYRES
                     "
     CDS             13432..13575
                     /locus_tag="ctg33_23"
                     /transl_table=11
                     /translation="MEIVLCCIIVEICECFQVLLIDLLGWYIFVYLLNKIWELILIEKS
                     NR"
     CDS             13686..14795
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Radical_SAM"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg33_24"
                     /sec_met_domain="Radical_SAM (E-value: 1.3e-09, bitscore:
                     29.4, seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MCFYAEDMDKKEKDLTFEEIKTISETAGQFNRLWVSGGEPTLREE
                     LPEIIEMFYKNNEIKDVNIPTNGLKPDRIVAWVKQIRQNCPELNINLSLSLDGFGDTHD
                     IQRGVPGNFYKAMGTLKLIEKNFADDGRVLKNLATVITKYNENEVEDLMIWMLGRFHLS
                     NHIIEAARGMTRDDGVKVLTEPTLRALQDKVVPIYNVYGERMAEETGGFRKPIARFFYL
                     GFIRTLYNVRATNIDHPTPWGMDCTAGETTLVIDYDGRFRACELREPLGNVKDYDCNIA
                     KIMESDAMKQEIAAIGHGDKANCWCTHGCWITSSLVFNPRKMITQVYKGYREMKKLNRP
                     LNISEELLQSIERKYALDEQKLVELGVRN"
     CDS             14973..15557
                     /locus_tag="ctg33_25"
                     /transl_table=11
                     /translation="MTTKLKDLFDTFLNIAASSQKLGINLIRVAILIIFVWIGGLKFYN
                     YEAEGIVPFVANSPFMSFFYAKSAPEYKEYKLKEGEFNEAKHQWHVENNTYIFSHGLGI
                     MIMAIGILTFLGIFSPKIGLIGSGLAIIMTLGTLSFLVTTPEVWVPDLGSGEHGFPLLT
                     GAGRLVIKDTAIIAGAIVVLSDCAQRILKKK"
ORIGIN
        1 gagtaccgaa tattgcggtt caacgtaatg ttcgttcgtt tctgtgaaaa ggacggcttc
       61 tttcttgccg gtcagggcag aatagcgaac caggttcatc tcattctgtt cgcggttcag
      121 ttcggcaata tagatactct tttcatccgg gctccaggcg atgttggtaa ggaacttttc
      181 tttcggggtt ccggtttcca gccagacggt ttcgcctgtc gagaggttgt acacaccgac
      241 tgttacctca tggctcttca tgccggccat cggatattta accggttcgg cttttgcctg
      301 gcgggcgtcg atattgacga taggatagtc tgtgaccatg ctctcgtcca tccggtagaa
      361 agccagggcg gaacctgccg gtgaccagaa cagtcctttg ctgatgccga attcacgttg
      421 atggactgcc tgtccgcaga cgattccatc ttttgtttca cgtgtaacaa tactcgtctg
      481 attctccggt gaaagaatct gtatgttgtt ccccaccgtg aatgccaggc agttattggc
      541 cggacagaag ttatagttcg atcctttgct gtccagctga taattgccaa ttatcttgtt
      601 ttcggcaaaa ttgtaatgca ggcggtggcc tttactggta aaagccagta ccggctggtc
      661 cttataggga accgaaaatc cgggcaggct gcctaccgtc ggaagtccgg ctgccgaaag
      721 cgcctcattg agtcggctgc gtgtaaaggc aacctgctct ttcttttcgg gtacgccgca
      781 tatcatactg tctcctttga catacaggta agtgtcccca caccattgta gctgtttgag
      841 actggccggg acgaacttat tgtgtgtctt ccctcccgga agcaggtcgt gtaatgtgag
      901 ttgtttgtcc tgtgccatca gcgtcatgga tgtagataaa gcgaacacgc aaagaaccag
      961 gaagtgttta atcttcaaag tcatcgttgt cttctcttct gaatggtttc ttgaatggac
     1021 ggccttctcc gcgttttctg tctccgaagt tctttctgtt tttagagaac ctgtcgtctt
     1081 cgtctttgta acgcattttg acggggcgtt tttcaccggc tttgtgcaaa atcggacgaa
     1141 ccgggcgttc accacgttcg cctccgaact gtttgcgggc aggacggccg tcaccgcgtt
     1201 cttcaccgaa gaaacgtttt cccggtgctg cggatgtacg ttcgttttcg tcttcactgt
     1261 gagcagcggc gaaacgacgg tcggggcggt ccatgcggtc ggtcttgaag ttcgggcgac
     1321 ctgcaggacg ggtgtcatat cttttttcag ggaacgaggg ccttgggcgt gaggcggaat
     1381 cttccgttct ttccgcgcct tcctcgttca atgctttctt atagtctttg ttctttcctt
     1441 caaatatttc gtaacaacgg tattcgcagt cgagcgagcc gttgatcagc ttcatccgtt
     1501 cgctgggacg caggccgatc ttgtcgaaac attcgtcttt gtagctgagt atccatactt
     1561 tatatccggt aaacacatgt ttgacgcgtt cgccgatcat attataaagt cccagcaggt
     1621 cgcgggagga gatacgttcg ccataaggcg ggttggttac caggataccc ggttgcggtg
     1681 cttccgtata ttgctggaaa ggcatcgttt tcagttcgac gtatttggcc aggcctgcgc
     1741 tacggatatt cttctgggcg atctcgatag cggccgggtt gatatccgaa ccgtagcatt
     1801 tgaaagtgaa ttcgcgttcc tggctttcgt cgttatagat gcggtcgaac agttcctggt
     1861 cgaagtcgat ccatttctcg aaagcgaact ccttgcggtg gatacccggg gcgatgttca
     1921 gggcgatcat agccgcttcg atcagcagcg taccggaacc gcacatcggg tcgacgaaat
     1981 tggattcgcc tttccagcct gtcttcagga tcataccggc agccagcact tcgttcagcg
     2041 gcgcttcggt ctgttccaca cggtatccgc gtttgtgaag gctctcgccc gaactgtcga
     2101 tagacaaggt acaatcgttg tgcgagatat gtatattgat gtataagtcg ggattgttta
     2161 cacgtacgga aggacgtttg ttgtgcttct ccataaagta gtcaacgatc gcatcttttg
     2221 tacggtaagc cacgaattta gagtgattga aatcttctga atagatcacg gagtcgatcg
     2281 cgaacgtctt gtccagtgac atatagtttt cccatacgac ctttttcact tccttataaa
     2341 ccgtatcggc atcttttgcc ttgaaatgat agatcggttt caggatgcgt aaggcggtgc
     2401 ggcaacagaa gttggctctg taaagcactt ctttatctcc tgtgaaggat accatccggc
     2461 ggccaatttc tatatcgttg gcgcctatag ctaataactc accggccagt atttcttcta
     2521 acccgtacag ggttttggcc accatttcaa atgtctcgtt attcatttgc gtgcgttgta
     2581 agaaaagata tttatttagt tactttattt tgtgtaatga cagcaccggg gggaacatct
     2641 ccggtgatcc agacgttgcc gcatatcgtg gcacctttgc cgacccgtat tttccccaat
     2701 agcgtcgcgt tggagtagac ggtcacattg tcttccagga tgggatggcg ggggacaccg
     2761 cggatcgcgt tcccgttctc atcgggcggc agcttttctc cggcaaggct gacaccctgg
     2821 aagatgcgta cgttattccc gatcacactg gtttcgccga tcacggtacc cgtgccgtgg
     2881 tcgatagaga aataatgtcc tatctgagct cccggatgaa tgtcgatacc ggtttcggaa
     2941 tgagccattt cggtgatcat ccggggtata aaaggaacgc ccaacttata aagctggtgc
     3001 gctatacgat aattgcctat tgcccggaag cccgggtaac agaagataac ttcattgatg
     3061 ttttgtgctg ccggatcacc gttgtaggcg gcttcggcat cggtggcaag cagacagcgc
     3121 atttccggca gtgtggaaat gaacgcttcg gaaagttttt ctgcctggct gaagatcagc
     3181 tcttccgcac aggaagtaca gctggtgtcg gccaggcaaa ggcccgcata gatttgacgg
     3241 ctgagcagct cgtgcaactt ttcaatattg accccggtat ggaaacggat cgtctgtgta
     3301 ctgatccgcg cattcccgta atagccagga aacaggattg cacggcacaa gtcaatgatc
     3361 tcctccagta cttcacctga aggcaatgcc tcttcatcgc ggtaggcatg aaacagttgt
     3421 ttgtatgaac attcgtccga aagcttttct actgtttcat tcaatacctt gctatgcttt
     3481 tgcaatccca ttattttgaa agtcttattt tgggcaaaag tacattaaat atctgatata
     3541 tgtgtacttt taataggtta taactgcttt gaaatgcgtt tccggcggcc gttgatcagt
     3601 aaagaagtcg gagaatgtca ctttgaagat gatgaaaccg tctttggtgt attcggctgc
     3661 ataggtttcc gtccagatat tattctcttt atctattcga ttgacagggt tgggtaatgc
     3721 agtttgtgct tctttgtctt cgccgtgatc cagatacatg taacaggtaa ttaagccttc
     3781 tttataagca tcctgatata tgtcgaaatc tttatcggca attctgtact catacatgta
     3841 aaaaggttcg ttattaccat tgtcgactaa ttcccagtcg cttgacttaa cttgtatatc
     3901 cttgtcaaat atccagtagg ttataccgcc atcttccccg tctcgtcccg gagggcccat
     3961 cggtccttcg catgaagcga acaggaacac cattaaaaat attgctaaca gatttttcat
     4021 atattcactc tcttaaatgt ttagtatttc ttgtgcggtg ccccgaactc tttgcatgtt
     4081 acttcatcga ggtctaccag ccatattttt acgtttttca cagccgggtc ggaataacgg
     4141 aattccttgt ccgaatactg tttcataatt atatccagcg cttccgtttt cttgtcgaag
     4201 tcttcttcaa accgcacttt accccatgcg ataacgcttt tggaacgcat acggtagctg
     4261 caagccactt cgggatgctg gaataccaga tcatggtcgg tgctgaaggt gatgcaaacc
     4321 ttcgggttac gttccaggat tgagatactt cggccttcct gcgctgaatg taaatagata
     4381 acaccgttcc gatagccaaa gttcatggga ataacgtaag gcgtaccatc cgtatcagcc
     4441 agtccgacga aacagacatc gcaactacgg ataatctcct cgatatgttc tttctctgtg
     4501 tgtaccagtg tcttcattac tatttttaat tatgcttttg caaacatagt aaaaaagttc
     4561 aacttctcgg acttactttt gcgactttat tatatatgta ctgttttcgt caatgtgtca
     4621 aaatgtcaaa tagcccttct gtcagtgagc tgtacgtgtc ctaaatcagg tttgttgttt
     4681 ttattcgctc tacgggatga ttgcgaatgt ctttatttta attgttgatt aataaatgtg
     4741 gctttatgtt tgatgatgtg tggtagttgt tgataaatgt cgtaaagtac atttgaaata
     4801 tatgaatgtg ctgttcgggt ttggtttgga tatttactcg ttctggagat aaaatgtgtt
     4861 gtttagcatg tgatttgagg tcccaaggcc tgtttaaaat aacttttttg gacagaatta
     4921 acaaattttt catctgcaat aaatctccat ctcatttaaa atgaaaaaaa attcgtttta
     4981 aacgagatta caatttgttt aaaatgaaga gtgaaaatct atatgaatac gctaagtgtt
     5041 aaatattgtg ttttcggatc ttctatttct actgttttgt gaaatatagc agatacgtat
     5101 atgcggaaaa aatatacaaa atgatcttta atcgttgtaa attgtagcaa aatggtattt
     5161 tattgtctgt taaaaggatt ccggataaga aaacacttta tcaagcgatt tcctatattt
     5221 gtaactccaa ttaaatataa tacctgtatg aataaaacta tcctgcttgt tgtgttttgc
     5281 ttttccctgt tcgtttcggg gtattcacag ggaatacgct ttgattctta cccttctcat
     5341 ccccggttgc tggtaaagaa aggagaggag caaaagatta aatccgatct ggctcttaat
     5401 ccggaaatgc tccggttgca taactatctt ctcaagcaat gcgacgatct gatcacgacg
     5461 cctgtgctgg catataaaaa agaagggaaa cggttgctgg ccgtatcgcg tgaagccttg
     5521 cggcgtatct tctatctttc atatgcttac cggatgacag gagaggataa gtatcgtttg
     5581 cgggcagagc aggaaatgat tgccgtgtgt tcgtttgccg attggaaccc gtcccatttt
     5641 ctggatacgg gcgaaatgac tatggcggtt gcaatcggtt atgactggtt gttcgatcgg
     5701 ttatctccgg atgcccggag gctggtgcag gaggcgattc tgaataaagg ttttgccccg
     5761 tcgagggata aaagatataa ctggtttctg agagcgacca ataactggaa ccaggtctgt
     5821 aatgccggac tggtttacgg tgcacttgcc gttttagaag atcatccgga agaggcccgt
     5881 gaaatcattg aacgtgcttt atctacagtc ggcctgactt tgaaaggcta tggtcccgat
     5941 ggcgcttatc ccgaaggata taattattgg ggatacggga ctaccttcca ggttcttttg
     6001 aatgccgcgt tggaatccgc cctggggact gacggcggtc tctcttcggc tgaaggtttt
     6061 ctggcttctg cccgttttat gcagtttatg accggaacga ccggtaaatg ctttaacttc
     6121 agcgattccc gtgagagtgt ctttgctttg ccggctatgt actggtttgc cgacaagctg
     6181 caagacccta cactgctttg gaatgaaaag gatatgttga gtcgggcgga gttgtctttt
     6241 tcggatgagg agagccgttt ccttccgttg attccgattt atggttcaca atataaaatg
     6301 aatgaactgg tacctcctgc catgaaattg tgggcggcta acggacagac gcctgtcgtg
     6361 ctggtccgta cgggttggga gaatggagaa ggtttctatc tgggaataaa aggaggaacg
     6421 gcttcgacca gccatgccca tatggatgcc ggatcgtttg tgttcgatgc tttgggtgtt
     6481 cgctgggtgc aggacctggg gatgcaggaa tattattcgc tggaaaagga aaatgtagat
     6541 ttatggaata tgtcgcagaa cgggcagcgc tggaatgtgt tccgttataa taacctggcg
     6601 cataatacac tgactgtaaa cggtaaatac catgatgtaa acggttttgt acctgtgaca
     6661 aatatctatt cggaagcgca taaactcgga gcttctctga atatgacgga cttgttcggc
     6721 ggagaattgg aaaatgccgt ccgtgaagtt gctctgatca atgaaaaata tctgtcggtg
     6781 attgatcgtg taaaagctgg cagtcagccg gcaactgtca gatggacgat tgtaaccggg
     6841 gccattcccc gtgtattgga cagtcatatg gtggaactga caaaagacgg caaatgtatg
     6901 caactgatcg ttgatagtcc gtccgtaact tctgtgtccg tccttgataa tgtatcgaag
     6961 aatagctatg atgcttccaa tgagggaacc tgccgtatcg ttttcgatgt gagtctggaa
     7021 agcgggcagg agagcgatat caaagtccgg ctggttcctg ctgctgactg ataattacca
     7081 gaacagtgcc gttacggttg cgccaatcgt aaagtagtgt attttgtgct tgcttaaatg
     7141 gctctcgccg tagactggtt ggctgtctct gaggctggtt aagatttcgt aaggtgcttt
     7201 caggaacgta taatcgtaat ctacgaacat acggataccc aggttgcggc tgacgatccc
     7261 ggtcgctgaa atgcctgtgc gtaaaacata gttgctgcta ccgttgcctt tcataaaaac
     7321 aatattattt atggttccgt atgagggggg cttttcctgt aagtccattt ccacttcatt
     7381 tttcaccagg taggaatatc cggcctggaa ctttgttcct aaaagcagct tgcttgctac
     7441 tggtaacgaa aaataaggcc ctgccgtaaa agtaaaaaca ccggtcggat cggcatggac
     7501 gcgggtgatg tcatatttgg ttgaaggggt tgttcctgta taaagcgaca tgtcgaatgc
     7561 catcgggctt gccagcgctg ttatttcgcc gccgataccg aaataaggat tgaagaagta
     7621 accgcctttt acgctgacat tggttgctcc cggcgagctc aggcgtatat ttttacctac
     7681 ctcgatactt ccgttgatga tactgtatcc tacggcgaac tccaggaaag aagggcgccc
     7741 tcctttgggg gcagactccc tgagcttgtc agggagattc aagcctttgt ccttgaagat
     7801 caggtctgcc agaaaatacc ctaactctgt ggataagatg ccgataccgg ccccggccag
     7861 tacgtcgctc agccagtggc ggttgttcag ttgccggctg aaagcggtgg ctgtggcgac
     7921 tgtatatccc ccgatactat ataacgggct gcgggtcaga ccatattccc ggtgcatgat
     7981 ggtagcagcc atgaaagcgg ttgccgtgtg tcccgaaggg aatgagttgt tctttgagcc
     8041 gtcggggcgt tcgcgtttga tcgtatattt catgctgttg acggtagcgg ccatgatcgt
     8101 tgccgaaaaa gcgttcgata cgatcatccg gggccatgaa ctacgacttt ccacaccgcc
     8161 gagcttcatc ccgtaaacag caagcaacgg agtatattgc agaaaatcat cgtatctgta
     8221 atggaagttg ggcgtatgcg tattgcgcaa tgtccggaat ttatcaccct gcccatatgt
     8281 tatggctgaa atggcgaaaa gaggaacagg gacacgtagc atctggtata ccttattctc
     8341 tgatattttg ttgtaagtgg tttcaaattc atgttcttta tttatgaatc tcgtactatc
     8401 ttttcactga gcacgaacag acggtataaa aatcatcata aataagaagc tcagcatttt
     8461 acgttgtaac atacgatccc ctgattatgc cacgaagata taaaaatgcc ggttagtact
     8521 ggttacattt ttgttaattt atttattgaa taggatttac cgtttgtccc tcctgaaatg
     8581 tataggtttg attgacgaaa tatttcttta atcgtttgcg tgatacgtgt atttagcata
     8641 cctttgcctg ataattgagt atattgatat gaatttctaa aaacaattaa ataacttaaa
     8701 ttattatctt atgtggttac ttaattcttc tatcgggaag aagctgataa tgagtgtatc
     8761 aggccttttt cttgttttgt tcttattgtt ccacttgtca atgaatgtgg cggctgcttt
     8821 ctcgggagaa gcctataaca tgatttgttc attgttggga gcaaattggt atgccgtggc
     8881 agcaacattg gtgctggcag caggcgttgt gattcacttt gtgtatgctg ttctccttac
     8941 actgcaaaac cgtaaggctc gcggtaacga ccgttatgca attaacgctc gtccgaaagg
     9001 tgtggaatgg gcatctcaga acatgctggt actgggtatt atcattatcc tgttcatggt
     9061 gttgcacttc agccagttct ggtataagat gatgttcgcc gaactcctag gcaatcacat
     9121 ggtaacactt tgcgacggaa caacaaccgt atctcctcag gacggtgcag cgtttatcaa
     9181 ctactatttc cagggtaata tcctgaatac agtgctgtat ctggtatggt acgtagcttt
     9241 gtggttccac ctgactcacg ggttctggag cgctattcag actatcggtt ggagtaacac
     9301 gatctggatg aaccgttgga tctgcatttc caagattgta gcaaccgtta tttgcgtagt
     9361 gtttgctatc attactatcg ttttctacct gaatggtgta ggtggtgact atgtagctgt
     9421 ttgtgcagga cattaattta aggtgtaaca atattgaaaa taaatcatta tgactcaaat
     9481 agattctaaa atccctcagg gcccgttggc tgagaagtgg aaaaattata aagatcatca
     9541 gaaactggtg aaccccgcga acaaacgtcg tctggacgtg attgtagttg gtactggtct
     9601 ggccggtgct tctgctgctg cctctctggc agaaatggga ttcaacgtat tgaacttctg
     9661 tatccaggat tctccccgtc gcgcacactc aatcgccgca cagggtggta tcaatgctgc
     9721 aaagaattat cagaatgatg gtgactctgt ttaccgtctg ttctacgata caatcaaagg
     9781 tggtgactat cgtgcccgcg aagcaaacgt ttatcggctg gctgaagttt ccaactctat
     9841 tatcgaccag tgcgtagcac agggtgttcc tttcgctcgc gaatacggtg gtctgctgga
     9901 taaccgttca ttcggtggtg ctcaggtatc ccgtacgttc tatgcccgcg gtcagaccgg
     9961 acagcagttg ttgctgggtg cttactctgc tttgagccgt atgatcggtt tgaacaaagt
    10021 aaagatgtat acccgccacg aaatgctgga cgttgtgaag gtggatggcc gtgcccgcgg
    10081 tatcatcgca cgtaacctga tcacaggtca gatcgaacgt ttctctgctc acgcagtagt
    10141 ggtggcaaca ggtggttatg taaatacttt cttcctgtct actaacgcaa tggcttccaa
    10201 cggttctgct gcatggcagt gctacaagaa aggtgcttac ttcgctaacc cttgtatggt
    10261 gcagatccac ccgacttgtg taccggtgaa aggtgactac cagtctaagc tgactttgat
    10321 gtctgaatca ttgcgtaacg acggtcgtat ctgggttccg aagaaactgg aagatgcaaa
    10381 agcattacag gccggaacta agaaagggaa agacattcct gaagcagacc gcgactacta
    10441 tctggaacgc cgttatccgg cattcggtaa cctggttccg cgtgacgtgg cttcacgtgc
    10501 cgctaaagaa cgttgcgacg ccggcttcgg tgtgaacaac acaggtctgg ccgtgttcct
    10561 cgacttctcc gacgccatca accgtctggg taaagatgtt gtaaaagcta aatatggtaa
    10621 cttgttcgac atgtacgaag aaattaccaa cgacgatcca tacgaaactc cgatgatgat
    10681 ttatcctgca ttgcactact cgatgggtgg tctgtgggtt gactatgaat tgatgacttc
    10741 tattccgggt ctgttcgcta tcggtgaagc taacttctct gaccacggag ctaaccgtct
    10801 gggtgcttct gcgttgatgc agggattggc cgatggctac tttgtattgc cttatacaat
    10861 ccagaactat ctgtcagacc agatccaggt tccgcgtttc agtaccgacc tgcctgagtt
    10921 tgcagaagct gaaaagggga tcaaagaccg catcaagaaa ttgatgagta tcaagggtaa
    10981 agagtcggta gattctatcc ataagaaact gggtcatatc atgtgggaac atgtaggtat
    11041 ggcacgtgat gcaaaaggtt tgcaggaagc gatccagatg ttgaaagagc tgaagaaaga
    11101 gttctggagt aatgtatata ttccgggtga agccgataac ctgaacgtag agttggataa
    11161 ggcattgcgt ttggctgact ttattgagat tggtacattg atggcacacg atgcattgga
    11221 ccgtgccgaa tcttgtggag gacacttccg tacagagcac cagaccgagg aaggcgaagc
    11281 cctgcgtcat gacgataagt tcatgtacgt atcttgttgg gaataccagg gtgaagacaa
    11341 agatccggtt atgctgaagg aagatttgaa ctatcagttc gttgttcctc aaacacgtaa
    11401 ctacaagaag taataatcat caatcacaaa aattagaatc atggataaag atataaaagt
    11461 aacacttaaa gtttggcgtc agaaaagtcc gaaagataaa ggacaatttg agacttacca
    11521 aatagacaaa atcaatcaga gtgtttcttt cctggaaatg ttagacattt tgaatgaacg
    11581 tttggtcagt gaaggtaaag agccgatcgt attcgatcac gactgtcgtg aaggtatctg
    11641 cggtatgtgt tctttgtatg taaacggaca tccgcacgga cctgcaaccg gcgcaactac
    11701 ttgccagctt tatatgcgtc gcttcaatga tggcgaaact attacaatcg aaccgtggcg
    11761 ttctgccggt ttcccggtaa tccgcgactt gatggtagac cgttatgctt acgataaaat
    11821 tatccaggca ggtggtttcg tatcagtgaa cacaggtggt gtacctgatg ccaattcaat
    11881 cgctattcct cgtgcagatg ctgaaatggc tatggatgct gctgcatgta tcggttgcgg
    11941 tgcttgtgct gctgcttgta agaacggttc ggctatgttg ttcgtttctg caaaggttag
    12001 ccagttggct ctgttgcctc agggtaaggt agaagctgct cgtcgtgcga aagcaatggt
    12061 tgccaagatg gacgaactgg gcttcggtaa ctgtaccaac acgcgtgctt gcgaaatgga
    12121 atgtccgaag aacatctctg tcagcaacat cgctcgtttg aaccgcgagt tcatttgtgc
    12181 taaattgcaa gactaatata cattatatat gtatgtccgg agaggcgttg cttatggcgg
    12241 cgcctcttct tttttgcccc tattttaaca tttctgaagt catagataaa tatcttgaat
    12301 gttgttagtg tttcttatat gctatacaac actaattagc attttaacta ttgacaagtt
    12361 ggagaatacc tgtatctttg tactatggtt ttttcataat agtattagat ttaaggttaa
    12421 caaagttggt tagggcttgt cgtgagacag gctttaattg tttatagggg tttgcgtccg
    12481 gcatatccct ttttttagct ctccctgtat tcctgcggag tcattcctac atgttgccgg
    12541 aaatatttgt tgaagaacga aaggttgtcg aagcccaggg cgaatgcaat tttcttgacc
    12601 ggcatatcgg tcgatttaag ctgcgctttg gcatccataa tgatgatatt gctcaggata
    12661 tccaatgcag tccgtccgct gacctttttt atcacataac agaaatgctg caaggtgatg
    12721 ttgagccttt tggcgtaata agacacgcta tgctctttcg tgtagttttc catcgccagc
    12781 tgtacgaact cccggcatat ttccatatta cgcgtcatgg gagcattgct atatggcgta
    12841 tgattcctgt ataattcaat aaccccttgc atgaagatag taaagatagc cttgataatc
    12901 tccttgtttt cgatggtttt aggcatggaa taagcattga tcagcaagtc gaaagcctgt
    12961 tggtagagta aggatatatg ctccggcaaa ggcatgatcg gactgtcgaa tatgacaggc
    13021 agatagttcg taatcgtctt tatataattg atatggctga cgaatacgga agaaaagcct
    13081 gcaaaacaca gttttacatc atcggaaacc tcatgtatct gaatgaagca acccgggggc
    13141 aaggtgataa agtcgttttt ccggatggta aactcagtta agtttacagt cgcatggact
    13201 gtcccttgta cgcaaagcac gaatatgcct gccttgatct tgcacgggaa acgtccgtat
    13261 tggttcagta tttcacctgt aatactgttt cctacaataa aatctacggg gaggtcgaat
    13321 ttaggaatat tgtcttccat acttttatat acacttaatt gaatgtacaa agatagtttt
    13381 tttgagacaa gttagtcgat aatcttaaat atagaacatc gaatcccaca aatggagatt
    13441 gttttgtgct gtataatagt tgaaatttgc gaatgttttc aagtcttgct gatagatttg
    13501 ttgggatggt atatatttgt ctatctgcta aataagatat gggagctaat actaatagag
    13561 aaatctaatc gataataaca atgagtacga aaagaacaaa gagctctttc aggacaatga
    13621 gcacaaacag aaaattagaa tctgttttcc tgtttgtcac aggacggtgt aatgctaaat
    13681 gtaaaatgtg tttctatgca gaagacatgg ataaaaagga gaaagacctg acttttgaag
    13741 aaatcaagac aatctccgaa acagccgggc agttcaaccg tttgtgggta tccggcggtg
    13801 aaccgacact gcgtgaggag ttacctgaaa ttatagagat gttctacaag aataacgaga
    13861 taaaggacgt gaatatccct accaacggat tgaagcctga ccggatcgtc gcctgggtaa
    13921 aacagatccg ccagaattgt ccggaactga atatcaacct gagcctttct ttggacggtt
    13981 tcggtgatac gcatgatata cagcgcggcg ttcccggcaa tttctacaaa gcgatgggga
    14041 cactgaagct gattgaaaaa aactttgctg acgacggcag ggtgttgaaa aacctggcca
    14101 ccgtaatcac caaatataac gagaatgagg tcgaggatct gatgatatgg atgctgggac
    14161 gtttccatct ttccaatcat attatcgaag ctgcacgcgg catgacccgc gacgacggag
    14221 tgaaggttct taccgagcct actttacgcg ccttgcagga taaggttgtt cctatttata
    14281 atgtatatgg agagcgtatg gcggaggaaa ccggtgggtt cagaaaacct atcgcccgtt
    14341 tcttctacct gggtttcata cgtacattat ataatgtacg tgcgaccaat atcgatcatc
    14401 cgaccccctg gggtatggat tgtacggccg gcgaaacaac actggtaata gactatgacg
    14461 gtcgtttccg tgcctgcgaa cttcgcgaac cgctcggtaa tgtaaaggat tatgattgca
    14521 atatcgcaaa gattatggag agcgatgcca tgaaacagga gattgccgct atcggtcatg
    14581 gtgacaaggc taactgctgg tgtacgcatg ggtgttggat cacttcatcg cttgttttca
    14641 atccccgcaa gatgatcacg caggtctata aaggataccg ggagatgaag aagctgaacc
    14701 gtcctctgaa tatcagtgaa gagcttttgc agagcatcga acgcaaatat gccttggacg
    14761 aacagaaact ggtggagctg ggggttcgta attaaaatag ttccgataac ggatcattta
    14821 taaagccggt tgacgggaaa tatacctctg ttaaccggct ttattgtgtt taagggaata
    14881 attgtcaaat tatctggtag aattgccatt tcccataggg gaaaaatgtc ggatctttgc
    14941 atcataagtt aaactgataa acaaagaaag acatgactac taaattaaaa gatttattcg
    15001 acacatttct gaacattgca gcttcttcac agaaactggg tattaacctg atccgcgtag
    15061 ctatcctgat tatattcgta tggatcggcg ggctgaaatt ctataattat gaagcggaag
    15121 ggatcgttcc ttttgtggca aacagtccgt ttatgagctt tttctatgca aagagtgcac
    15181 cggaatacaa agaatataag ttgaaagaag gtgaattcaa tgaagccaag catcagtggc
    15241 atgtagaaaa caatacctat attttttcac atggactagg cattatgatc atggcgatcg
    15301 gtatcctgac tttcctgggt atcttttctc cgaaaattgg cttgataggt tccggactgg
    15361 cgatcataat gacattgggt acgctttcat tcctggtgac aacacctgaa gtatgggtgc
    15421 ccgatttggg aagcggagaa catggtttcc ccttactgac cggagcaggt cggctggtaa
    15481 taaaagatac ggcaatcata gccggagcga tcgtggtatt gtccgactgt gcacaacgta
    15541 tattaaagaa gaaataggaa caaaaagtgt ttattttaac actttggaag caaaaaacaa
    15601 acatattgaa ccttgttagc ttttcttata gtgtatgaaa caccatttag cataaaacct
    15661 cttgacaggt ttggattaag cagtatattt acatcgtggt tttttcataa tagtattaga
    15721 tttaaggtta acaaagttgg ttagggcttg
//
