LOCUS       c00134_gnlPro..         6578 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|ALOPODML_134.
ACCESSION   c00134_gnlPro..
VERSION     c00134_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-07 17:15:35
            Original ID  :: gnl|Prokka|ALOPODML_134
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 6578
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..6578
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[2:6577]"
                     /cutoff="10000"
                     /detection_rule="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /neighbourhood="10000"
                     /product="succinate2propionate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      3..6577
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /neighbourhood="10000"
                     /product="succinate2propionate"
                     /protocluster_number="1"
     cand_cluster    1..6578
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /kind="single"
                     /product="succinate2propionate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..6578
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="succinate2propionate"
                     /region_number="1"
                     /rules="(minimum(4, [AcetylCoA_hyd_C, AcetylCoA_hydro,
                     B12-binding, Biotin_lipoyl, Glyoxalase_4, HMGL-like,
                     MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma, PYC_OADA]) and
                     minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /tool="gutsmash"
     CDS             complement(3..1130)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: AcetylCoA_hydro"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: AcetylCoA_hyd_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg134_1"
                     /sec_met_domain="AcetylCoA_hyd_C (E-value: 3e-14, bitscore:
                     42.2, seeds: 181, tool: rule-based-clusters)"
                     /sec_met_domain="AcetylCoA_hydro (E-value: 1.4e-44,
                     bitscore: 141.3, seeds: 5, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSYKVLTPEEAASLIKHGHHIGLSGFTPAGTAKAVTAALAKIAEA
                     EHEKGNPFQVSVFTGASTGDSCDGILSRAKAIRYRAPYTTNVDFRKAVNNGEIAYNDIH
                     LSQMAQEVRYGFMGNVDIAIIEACEVTADGKIYLTAAGGIAPTICRLADKIIVELNAAH
                     SKSAMGLHDVYEPLDPPYRREISIFKPSDRIGKPYIQVDPKKIVGVVETNWPDEARSFA
                     AADPLTDKIGQNVADFLAADMKRGIIPSTFLPLQSGVGNIANAVLGALGRDKTIPAFEM
                     YTEVIQNSVIGLIREGRVKFGSACSLTVTNDCLEGIYRDMDFFRDKLVLRPSEISNSPE
                     VIRRLGVISINTAIEADIYGNVNSTHIGGTKMMNGI"
     CDS             complement(1191..1970)
                     /locus_tag="ctg134_2"
                     /transl_table=11
                     /translation="MNSAASFSTPPEEEGPCGDWTYHEWAEAFSTNDLARTLPPGHIAV
                     CRVQTGGRGRFNRKWIGEEGGLWASFTVPLSAPEDTAADVHWGHLPLVAGLALFNMLRG
                     MGLDSVRLRWPNDLLAGKSKLAGILVERPAENMAVIGIGINVFNDVSSIAGEIKDPPAR
                     LADLVRDCPSLHAVMASLGSHLNQVLSVFSHGGVPALQEGLSRAWAGERPVSILTDDET
                     VRGIFTGIDDQGNPVLSLPAGTVRTIPAHLINRLLEE"
     CDS             complement(2008..3633)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: OAD_beta"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg134_3"
                     /sec_met_domain="OAD_beta (E-value: 7.9e-160, bitscore:
                     520.3, seeds: 229, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGVFSLSWQMVGMWGIAILLLYLGVAKQYEPLLMVPIAFGALIAN
                     IPDNGMLITQLNQQVISSNEQGEVTATSLNNVGYLRVHVAPLQQAPSKVPANLTTPESR
                     AQYQEIMQQPMQVYPGSQLTVSKIKSVRESQEKAKADAARLGDDSLTVDPNLKDFQNVT
                     EDNGNEPVFLLTNGEGTTVVRQQGVNYFDTSGNRIPVDLKTQKLEPLVVSAAGKYVAVG
                     QHTQELLVTSIHGGLYDWIGLGIKAEIFPPIIFLGVGALTDFGPLLAAPRTLLLGAAAQ
                     VGVAATFFMALFMGFTPNESASIGIIGGADGPTSIFLTMKLAPHLLGAVAVAAYTYMSL
                     VPLIQPPIMALLTTKKERLIRMKSLRTVSKSEKLFFAVLVTIVTILLIPDASPLIGMLM
                     LGNFLRECKVTERLVQASQNEIINIVTIFLGTSVGLTMQGDRFLQSETLLIILLGIVAF
                     GVATAGGVIAAKIMNLIWRKNPVNPLIGSAGVSAVPMAARVSHNVGQKYDPSNYLLMHA
                     MGPNVAGVIGTAVIAGYYIATLAK"
     CDS             complement(3751..4152)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: Biotin_lipoyl"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1024:Biotin-requiring enzyme (Score: 58.8; E-value:
                     1.2e-18)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg134_4"
                     /sec_met_domain="Biotin_lipoyl (E-value: 1.4e-19, bitscore:
                     58.8, seeds: 40, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKLRITVDGKVFDVSVELLDQVSSTTAAPAPAPVAAPAPAASAP
                     VAAPAPAPAPAPAPAAAGAGDVPSPLAGKVVSLDVAAGAPVKAGDQILTLEAMKMNTII
                     YAPASGTLTAFCVNPGDTVQEGQALAKIG"
     CDS             complement(4225..4677)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: OAD_gamma"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg134_5"
                     /sec_met_domain="OAD_gamma (E-value: 2.9e-10, bitscore:
                     29.7, seeds: 234, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLLTTLAFAFAQGIANVMNNLNYQVVGIMVVMLCLGGMAVILTVS
                     GSIAAAIQNRAKAKTAAPVAVSAAAPAAAGKPGMTPEMLAILSAAVDSAMTELTPEMVA
                     VISAAVDAGLDGMSHRIVEIKQSPGSGYAAAGRAEIFASHRIRPSR"
     CDS             complement(4699..6264)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: CT_Vparvula"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg134_6"
                     /sec_met_domain="CT_Vparvula (E-value: 6.4e-217, bitscore:
                     709.8, seeds: 132, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAIDPKLIDDLNSRRKKVILSGGQEKIDKRHEKGEMTARDRMGYL
                     FEEGTFSEIGMHVRHNCHNFGMGKKEIPGDGVVSGFGLVDGRPVACAASDFLAQGGSLG
                     YMHAMKIADAQKYALKAGIPMVTVNDSGGARLQEGVAALSGYAQVFYNNVLASGVVPQI
                     SMILGPCAGGAAYSPALTDFIIMRNSGNAGMYITGPKVIEQVTYEKCTMDDIGSAAIHA
                     TVSGNVHFVADSDAHAMDILKRLLSFLPSNNTEEPPHKLDTPLDLSADEGMSDLIPGDN
                     RTPLDVQPIISRLVDNGDFLEVHKDFAKNVVVGFGRICGVVVGIIANQPNVKAGCLDID
                     SSDKAARFIRFCNAFNIPLVNLVDVPGFLPGKNQERGGIIRHGAKLIFAYSQATVPKVT
                     LIMRKAYGGAYIAMCCKDLGADAVFAWPGAEIAVMGAEGAVPVLYGRELKAVEDPAEKA
                     KRQGELLEEYREAFYNPYVAAGMGQITEVINPEETRAKIAFALRTLLNKKEVRPAKKHG
                     NIPL"
     CDS             complement(6296..6577)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: Glyoxalase_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg134_7"
                     /sec_met_domain="Glyoxalase_4 (E-value: 2.3e-15, bitscore:
                     45.8, seeds: 51, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VAGVHIELLEPTSPESAIAKAIEKKGEGIHHIAFKTNDIAGNISQ
                     AKEAGLTVLNDPPVPGAHNTQVTFLHPKCTFGVLTEFCQHPGGCECGK"
ORIGIN
        1 ccgatgccgt tcatcatctt cgtgccgcca atgtgcgtgg agttgacgtt cccgtaaatg
       61 tcggcttcaa tggcggtgtt gatggagatg acgccgagac ggcggataac ttccgggctg
      121 ttggatattt ccgagggacg gagcaccagt ttgtcgcgga aaaagtccat atccctgtaa
      181 atgccttcca ggcagtcgtt cgtcacggtc agggagcagg cgctgccgaa ttttacgcgg
      241 ccctcccgaa tcaggccgat gacggaattc tggatgactt ccgtgtacat ctcgaacgcg
      301 ggaattgtct tgtcgcggcc cagggcgccc agcaccgcgt ttgcgatgtt gcctacgccg
      361 gactggagag gcaggaacgt ggagggaatg atgccccgtt tcatgtcggc agccaggaaa
      421 tcggccacgt tctgcccgat tttatcggtc aggggatccg ctgcggcgaa ggaacgggct
      481 tcatccggcc agttggtttc cacaacgccc acaatctttt tcgggtcaac ctggatgtac
      541 ggcttgccga tgcggtcgct gggtttgaag atggagattt cgcggcggta gggaggatct
      601 aggggttcgt aaacgtcgtg caggcccatg gcgctcttgc tgtgggcggc gtttaattcc
      661 acgataattt tgtctgccag gcggcagatg gtgggagcga tcccgcccgc ggccgtcagg
      721 taaattttgc cgtcggccgt gacttcacag gcttcaataa tggcgatgtc cacgttgccc
      781 atgaacccgt agcgcacttc ctgggccatc tgggacaaat ggatgtcatt ataggcgatt
      841 tccccgttgt tcaccgcctt gcggaaatca acgttggtgg tgtagggagc gcggtagcgg
      901 attgccttgg cccgggaaag gattccatcg caggaatcgc cagtggaagc accggtgaag
      961 acgctcacct ggaaagggtt ccccttctca tgttccgctt ctgcgatttt tgccagcgca
     1021 gccgtaacgg ccttggccgt tccggcgggc gtgaatccgc tcagcccaat atggtggcca
     1081 tgcttgatca ggcttgctgc ttcttctggt gtcagtacct tgtaactcat gtcagtgatt
     1141 tttgttggat gaaaaaagaa agaaaccccg tgtaaaacgg agcggcaggc tcattcttcg
     1201 aggagcctgt tgatcaggtg cgccggaatg gtgcggacgg tgccggccgg aagggatagc
     1261 acaggattgc cctgatcgtc aatccctgta aaaatgcccc ggacggtttc gtcatccgta
     1321 agaatggaaa ccggcctttc tccggcccat gcccgggaca gaccctcctg aagggcgggg
     1381 acgccaccgt gggaaaagac ggaaagaacc tggttcaaat gactgcccag ggaagccatg
     1441 acggcgtgca gggaagggca gtcccgaaca agatccgcca gccttgccgg agggtccttg
     1501 atttccccgg cgatggagga tacatcattg aaaacattga tgccgatgcc gatgacggcc
     1561 atgttctccg ccgggcgttc caccagtatt cccgccagtt tggatttgcc cgccagcagg
     1621 tcgttcggcc agcgcaggcg cacggaatcc agccccatgc cgcggagcat gttgaacagg
     1681 gccagccccg caaccagagg caaatggccc cagtgcacgt cggccgctgt atcctcagga
     1741 gcggacaggg ggacggtgaa ggatgcccac aggccgcctt cctcccctat ccatttgcgg
     1801 ttgaacctgc cgcggcctcc tgtctgaaca cggcagacgg caatatgccc cggggggagg
     1861 gtgcgggcca gatcattggt ggaaaaagcc tcagcccatt catgataagt ccagtcgccg
     1921 catggtcctt cctcctccgg aggggtggaa aatgaggctg cggaattcat gggacgggcc
     1981 gaggccggga gtaattttca attctggtta tttcgccaga gtggcgatgt agtagcccgc
     2041 gatgactgcg gtgccgatca cgcctgcaac gttcgggccc atggcgtgca tgagcaggta
     2101 gttggagggg tcgtacttct ggcccacatt gtgggagacg cgggctgcca tcgggacggc
     2161 ggagacgcct gcggacccga tcagggggtt gaccggattc ttgcgccaga tgaggttcat
     2221 aatcttggcg gcaatcactc cgcccgctgt tgccacgccg aaggcgacga tacccagaag
     2281 gatgatcagc agcgtttccg actgcaggaa gcggtcgccc tgcatcgtga gccccacgga
     2341 ggttcccagg aagatggtga cgatgttgat gatttcattc tgggaggcct gaaccaggcg
     2401 ttccgtcacc ttgcattcgc gcaggaagtt gccaagcatc agcatgccga tcagcgggga
     2461 tgcgtccgga atcagcaaaa tggtgacaat ggttaccagc acggcgaaaa acagtttttc
     2521 gctcttgctg accgttcgca gggatttcat gcggatgagg cgttccttct tggtcgtcag
     2581 caacgccatg atgggcggct gtatcagcgg aaccagggac atgtacgtgt atgcggccac
     2641 ggccacggcg cccagcaggt gcggggccag cttcatcgtc aagaagatgg aggtggggcc
     2701 gtcagcgccg ccaatgatgc cgatggacgc ggattcattc ggggtgaacc ccatgaacag
     2761 ggccatgaag aacgtggcgg cgacgcccac ctgggccgct gcgcccagaa gcagggtgcg
     2821 cggagcggca agcagcgggc cgaagtccgt cagggctcct acgcccagaa agatgatggg
     2881 cgggaaaatt tcagccttga tgcccagccc gatccagtca tacaggcccc cgtggatgga
     2941 ggtgaccagc agttcctggg tatgctggcc tacggccacg tatttgcctg cggcggaaac
     3001 caccaggggc tccagcttct gggttttcag atccaccgga atccggttgc cgctggtgtc
     3061 aaagtaattg acgccctgct ggcggacgac ggtggtccct tctccgttcg tgagcaggaa
     3121 gaccggttca ttgccgttgt cttccgtcac gttctggaaa tccttcaggt tggggtccac
     3181 cgtcaggctg tcgtcgccca ggcgggccgc gtcagctttt gctttttcct gggattcccg
     3241 cacggacttg atcttggaaa cggtcagctg gctgccgggg taaacctgca tgggctgctg
     3301 catgatttcc tgatactggg cacgggattc aggcgtggtc aggttggccg gcaccttgga
     3361 gggagcctgc tgaagcggag ccacgtgaac gcgcaggtac cccacgttgt tcagagacgt
     3421 ggcggttact tccccctgtt cattggagga gatgacctgc tggttcagct gggtgatgag
     3481 cattccgtta tccggaatgt tggcaatgag ggcgccgaaa gcaatgggaa ccatcaggag
     3541 cggttcgtat tgcttggcta cacccagata caggaggaga atggcaatgc cccacatccc
     3601 taccatctgc catgataggg agaagacgcc catcccctgt aaaaaggtga ttaatgaatc
     3661 aaaaagactc atagggaata tttttgtagc ggtttattat ctgagccgga gcccgggact
     3721 gttggcgttt ccgggctgcc gccgccggga ttaaccaatt ttggccagtg cctgtccttc
     3781 ctgaaccgtg tcgcccgggt tcacgcagaa agcggtgagc gtgccggagg cgggagcgta
     3841 gatgatggtg ttcatcttca tggcttccag cgtcagaatc tggtcaccgg ccttcacggg
     3901 tgcgcctgct gccacgtcca gggagacgac cttcccggca agcgggctgg gaacgtctcc
     3961 tgcgccggcg gcggccggag ccggcgcagg tgcgggagcc ggggccgggg cggccacggg
     4021 ggcggaagcc gcaggagcgg gagcggccac aggtgcgggg gccggcgccg cagtggtgga
     4081 ggacacctgg tccagaagtt ctacggatac gtcaaatact ttgccgtcta cggtgatgcg
     4141 aagtttcttc ataatagtgt gtggtatggg atattaagtt aaatgattcc gcctgggcgg
     4201 ggtaagggtg aataatgcag tagttcagcg ggaaggccgg atgcggtggg aggcgaaaat
     4261 ttccgccctg cccgcagccg catagccgga acccggggat tgcttgattt ccacgatgcg
     4321 gtggctcatg ccgtccaggc ctgcgtccac ggcggcggag atgacggcca ccatttccgg
     4381 cgtaagctcc gtcatggcgg aatccacggc ggcggaaagg atggcgagca tttccggagt
     4441 catgcccggt ttgcccgccg cagcgggagc ggcggcagac acggctacgg gagcggctgt
     4501 tttggctttg gccctgttct gaatggcggc ggcgatggag ccgctgacgg tcagaatgac
     4561 ggccatgcct cccaggcaca gcataaccac catgatgccg acaacctgat agttcagatt
     4621 gttcataacg ttggcgatgc cctgtgcgaa ggcaaaagcg agtgttgtaa gtaacatatg
     4681 aatccgttgg gatggatgtt agagcggaat gttgccgtgt ttcttggccg ggcgcacttc
     4741 cttcttgttc agcagggtgc gcagggcgaa ggcgattttg gcgcgggttt cttccggatt
     4801 gatgacttcc gtaatctgtc ccatgccggc cgccacatac gggttgtaaa aggcttcccg
     4861 gtattcttcc agaagttctc cctggcgctt ggctttttcc gccgggtctt ccacagcctt
     4921 cagttcgcgg ccgtagagta ccgggacggc gccttccgca cccataacgg caatttccgc
     4981 accaggccag gcgaagacgg cgtcagcgcc caggtccttg cagcacatgg cgatgtaggc
     5041 gccgccgtag gctttccgca tgatcagggt gactttgggc accgtggcct gggaataggc
     5101 gaagataagt ttggcgccgt ggcggataat gccgccccgt tcctggttct tgccgggcag
     5161 gaagccgggc acgtccacca ggttcaccaa cggaatattg aacgcgttgc agaaacggat
     5221 gaagcgcgcg gccttgtcgg aggagtcgat atccaggcag ccggctttca cattgggctg
     5281 gttggcgatg atgccgacca ccacgccgca gatgcggccg aatccgacga cgacattttt
     5341 ggcgaagtcc ttgtgtactt ccaggaagtc cccgttgtcc accagacggc tgatgatggg
     5401 ctggacgtcc agcggcgtgc ggttgtcgcc gggaatcagg tcgctcatgc cttcgtcagc
     5461 gctcaggtcc agcggagtgt ccagtttgtg gggcggttct tccgtgttgt tggaaggaag
     5521 gaaggaaaga agcctcttca ggatgtccat ggcgtgcgcg tcgctgtccg ctacgaaatg
     5581 gacgttgccg gacacggtgg cgtgaatggc ggcggagccg atgtcgtcca tcgtgcattt
     5641 ttcatacgtg acctgttcaa tcactttggg accggtgatg tacatgcccg cgttgccaga
     5701 attgcgcatg atgatgaagt ccgtcagggc gggggagtag gccgcgccgc ccgcgcaggg
     5761 gcccaggatc atggagattt gcggaaccac gccggaggca agcacgttgt tgtaaaacac
     5821 ctgggcgtat ccggaaaggg ccgccactcc ttcctggagg cgcgcgccgc cggagtcgtt
     5881 cacggtcacc atcgggatgc cggctttcag cgcatacttc tgggcatccg caattttcat
     5941 ggcgtgcatg tagccgaggg aaccgccctg ggccaggaaa tcggaggccg cgcaggctac
     6001 cgggcggccg tccaccaggc cgaaaccgga aacgacgccg tcgccgggga tttccttctt
     6061 acccatgccg aagttgtggc agttgtggcg cacatgcatg ccgatttccg agaaggtgcc
     6121 ttcctcaaag aggtacccca tgcggtcgcg ggctgtcatt tcgccctttt catgtctctt
     6181 gtcgatcttt tcctgaccgc cgctgaggat gactttcttg cggcggctgt tcagatcgtc
     6241 aatcaatttg ggatcaatag ccattggtct agtggtatgg tgaataggga gaatgttact
     6301 tgccgcattc gcagccgccg gggtgctggc agaattcggt caggacgccg aaggtgcatt
     6361 tgggatgcag gaaggtgacc tgcgtgttgt gagcgccggg gacgggcggg tcgttcagca
     6421 cggtaaggcc tgcttccttg gcctgggaga tatttccggc gatgtcattg gtcttgaaag
     6481 cgatgtggtg gatgccttcc ccttttttct caatagcctt ggcgatagcg ctttccggag
     6541 aggtgggttc gagcagttcg atgtggactc cggcaacg
//
